Guide to the Human Genome
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Search of human proteins with 10835047

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835047 sarcoglycan, epsilon isoform 2 [Homo sapiens]
         (437 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835047 sarcoglycan, epsilon isoform 2 [Homo sapiens]             907   0.0  
gi|150378454 sarcoglycan, epsilon isoform 1 [Homo sapiens]            893   0.0  
gi|150378535 sarcoglycan, epsilon isoform 3 [Homo sapiens]            868   0.0  
gi|4506911 sarcoglycan, alpha isoform 1 precursor [Homo sapiens]      318   8e-87
gi|208973226 sarcoglycan, alpha isoform 2 precursor [Homo sapiens]    151   1e-36
gi|22035548 amyloid beta A4 precursor protein-binding, family A,...    32   1.1  
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     31   2.5  
gi|194353992 amyloid beta A4 precursor protein-binding, family A...    30   5.6  
gi|22035550 amyloid beta A4 precursor protein-binding, family A,...    30   5.6  
gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo ...    30   5.6  
gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo sap...    29   7.4  

>gi|10835047 sarcoglycan, epsilon isoform 2 [Homo sapiens]
          Length = 437

 Score =  907 bits (2343), Expect = 0.0
 Identities = 437/437 (100%), Positives = 437/437 (100%)

Query: 1   MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH 60
           MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH
Sbjct: 1   MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH 60

Query: 61  VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA 120
           VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
Sbjct: 61  VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA 120

Query: 121 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL 180
           ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
Sbjct: 121 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL 180

Query: 181 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE 240
           GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
Sbjct: 181 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE 240

Query: 241 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE 300
           NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
Sbjct: 241 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE 300

Query: 301 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH 360
           YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
Sbjct: 301 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH 360

Query: 361 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL 420
           HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL
Sbjct: 361 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL 420

Query: 421 PHQTQIPQQQTTGKWYP 437
           PHQTQIPQQQTTGKWYP
Sbjct: 421 PHQTQIPQQQTTGKWYP 437


>gi|150378454 sarcoglycan, epsilon isoform 1 [Homo sapiens]
          Length = 462

 Score =  893 bits (2307), Expect = 0.0
 Identities = 437/462 (94%), Positives = 437/462 (94%), Gaps = 25/462 (5%)

Query: 1   MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH 60
           MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH
Sbjct: 1   MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH 60

Query: 61  VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA 120
           VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
Sbjct: 61  VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA 120

Query: 121 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL 180
           ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
Sbjct: 121 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL 180

Query: 181 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE 240
           GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
Sbjct: 181 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE 240

Query: 241 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE 300
           NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
Sbjct: 241 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE 300

Query: 301 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH 360
           YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
Sbjct: 301 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH 360

Query: 361 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQ-- 418
           HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQ  
Sbjct: 361 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQWS 420

Query: 419 -----------------------NLPHQTQIPQQQTTGKWYP 437
                                  NLPHQTQIPQQQTTGKWYP
Sbjct: 421 FAPVAQAGVQWSDLGSLQPPPPRNLPHQTQIPQQQTTGKWYP 462


>gi|150378535 sarcoglycan, epsilon isoform 3 [Homo sapiens]
          Length = 451

 Score =  868 bits (2244), Expect = 0.0
 Identities = 424/433 (97%), Positives = 424/433 (97%), Gaps = 9/433 (2%)

Query: 1   MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH 60
           MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH
Sbjct: 1   MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH 60

Query: 61  VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA 120
           VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
Sbjct: 61  VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA 120

Query: 121 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL 180
           ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
Sbjct: 121 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL 180

Query: 181 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE 240
           GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
Sbjct: 181 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE 240

Query: 241 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE 300
           NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
Sbjct: 241 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE 300

Query: 301 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH 360
           YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGV         IQLVH
Sbjct: 301 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGV---------IQLVH 351

Query: 361 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL 420
           HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL
Sbjct: 352 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL 411

Query: 421 PHQTQIPQQQTTG 433
           PHQTQIPQQQTTG
Sbjct: 412 PHQTQIPQQQTTG 424


>gi|4506911 sarcoglycan, alpha isoform 1 precursor [Homo sapiens]
          Length = 387

 Score =  318 bits (814), Expect = 8e-87
 Identities = 167/371 (45%), Positives = 234/371 (63%), Gaps = 15/371 (4%)

Query: 50  VYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDP---ITFNTNLMGYPDRPGWLRYIQR 106
           ++P  G +FVH L+ E F         P  ++  P   IT++ +L G+PD P WLRY QR
Sbjct: 28  LHPLVGRVFVHTLDHETFLS------LPEHVAVPPAVHITYHAHLQGHPDLPRWLRYTQR 81

Query: 107 TPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFI 166
           +P+  G LYGS T E+ G   +IE+TAYNR +F+T R  L++ I   E   LPYQAEF +
Sbjct: 82  SPHHPGFLYGSATPEDRGLQ-VIEVTAYNRDSFDTTRQRLVLEIGDPEGPLLPYQAEFLV 140

Query: 167 KNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMV 226
           ++ + EE+L S     FL A+  +W+P  L  +N+TSALDRGGRVPLPI   KEGVY+ V
Sbjct: 141 RSHDAEEVLPSTPASRFLSALGGLWEPGELQLLNVTSALDRGGRVPLPIEGRKEGVYIKV 200

Query: 227 GADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQ 286
           G+  PFS+CL+ V +P +  RC+Q   P+++C       F +DWC ++LVDK+      +
Sbjct: 201 GSASPFSTCLKMVASPDSHARCAQGQPPLLSCYDTLAPHFRVDWCNVTLVDKSVPEPADE 260

Query: 287 EVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGV 346
               G+GIL     + PP+++   RD+  D L+TL VP  VAL+L L+LAY+MCCRREG 
Sbjct: 261 VPTPGDGILEHDPFFCPPTEA-PDRDFLVDALVTLLVPLLVALLLTLLLAYVMCCRREGR 319

Query: 347 EKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNY 406
            KR++ T DIQ+VHH  I  +T+ELR M+ +RE+  PLSTLP+F+  TGE +PP      
Sbjct: 320 LKRDLATSDIQMVHHCTIHGNTEELRQMAASREVPRPLSTLPMFNVHTGERLPP----RV 375

Query: 407 DSTNMPLMQTQ 417
           DS  +PL+  Q
Sbjct: 376 DSAQVPLILDQ 386


>gi|208973226 sarcoglycan, alpha isoform 2 precursor [Homo sapiens]
          Length = 263

 Score =  151 bits (382), Expect = 1e-36
 Identities = 80/176 (45%), Positives = 110/176 (62%), Gaps = 10/176 (5%)

Query: 50  VYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDP---ITFNTNLMGYPDRPGWLRYIQR 106
           ++P  G +FVH L+ E F         P  ++  P   IT++ +L G+PD P WLRY QR
Sbjct: 28  LHPLVGRVFVHTLDHETFLS------LPEHVAVPPAVHITYHAHLQGHPDLPRWLRYTQR 81

Query: 107 TPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFI 166
           +P+  G LYGS T E+ G   +IE+TAYNR +F+T R  L++ I   E   LPYQAEF +
Sbjct: 82  SPHHPGFLYGSATPEDRGLQ-VIEVTAYNRDSFDTTRQRLVLEIGDPEGPLLPYQAEFLV 140

Query: 167 KNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGV 222
           ++ + EE+L S     FL A+  +W+P  L  +N+TSALDRGGRVPLPI   KEG+
Sbjct: 141 RSHDAEEVLPSTPASRFLSALGGLWEPGELQLLNVTSALDRGGRVPLPIEGRKEGL 196



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 37/76 (48%), Positives = 52/76 (68%), Gaps = 5/76 (6%)

Query: 342 RREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPL 401
           R+EG+ KR++ T DIQ+VHH  I  +T+ELR M+ +RE+  PLSTLP+F+  TGE +PP 
Sbjct: 192 RKEGL-KRDLATSDIQMVHHCTIHGNTEELRQMAASREVPRPLSTLPMFNVHTGERLPP- 249

Query: 402 HTDNYDSTNMPLMQTQ 417
                DS  +PL+  Q
Sbjct: 250 ---RVDSAQVPLILDQ 262


>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
           member 1 [Homo sapiens]
          Length = 837

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/35 (45%), Positives = 20/35 (57%)

Query: 285 YQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLI 319
           YQE +R  GI P+    K  SD L ++D Y D LI
Sbjct: 612 YQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLI 646


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 18/83 (21%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 297 DGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDI 356
           +G ++   + +++S        + +AV    AL++  I+ Y  CCR    +  N +  + 
Sbjct: 217 EGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIYCCCCRG---KDDNTEDKED 273

Query: 357 QLVHHSAIQKSTKELRDMSKNRE 379
              +  A ++  ++LR++S+ RE
Sbjct: 274 ARPNREAYEEPPEQLRELSRERE 296


>gi|194353992 amyloid beta A4 precursor protein-binding, family A,
           member 2 isoform b [Homo sapiens]
          Length = 737

 Score = 29.6 bits (65), Expect = 5.6
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 285 YQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLI 319
           YQE +R  GI P+    K  SD + +++ Y D LI
Sbjct: 512 YQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLI 546


>gi|22035550 amyloid beta A4 precursor protein-binding, family A,
           member 2 isoform a [Homo sapiens]
          Length = 749

 Score = 29.6 bits (65), Expect = 5.6
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 285 YQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLI 319
           YQE +R  GI P+    K  SD + +++ Y D LI
Sbjct: 524 YQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLI 558


>gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo
           sapiens]
          Length = 740

 Score = 29.6 bits (65), Expect = 5.6
 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 7/98 (7%)

Query: 23  RRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGV-LFVHVLEREYFKGEFPPYPK----P 77
           R M    TG  ++  Y    + +  +N   +  + + ++    +YF  E  PYPK    P
Sbjct: 180 REMGINCTGKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLP 239

Query: 78  GEISNDPITFNTNLMGYPDRPGW--LRYIQRTPYSDGV 113
           G  +      N N  G P  PG+    Y  R    +GV
Sbjct: 240 GTAAQRGNVLNLNGAGDPLTPGYPAKEYTFRLDVEEGV 277


>gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo
           sapiens]
          Length = 342

 Score = 29.3 bits (64), Expect = 7.4
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 209 GRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVIT-CDKKFRT 264
           G  P PI     G++   G +  FS  +  V N + Q +  Q ++ ++T C K F T
Sbjct: 275 GNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPT 331


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,993,554
Number of Sequences: 37866
Number of extensions: 854503
Number of successful extensions: 1792
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1776
Number of HSP's gapped (non-prelim): 12
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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