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Search of human proteins with 10835015
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform
a precursor [Homo sapiens]
(961 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ... 1959 0.0
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform... 1632 0.0
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ... 1623 0.0
gi|40255245 G protein-coupled receptor 51 [Homo sapiens] 473 e-133
gi|23308585 G protein-coupled receptor 156 [Homo sapiens] 119 2e-26
gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens] 65 2e-10
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens] 65 3e-10
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur... 60 1e-08
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur... 60 1e-08
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens] 59 2e-08
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs... 55 2e-07
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso... 55 2e-07
gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens] 55 2e-07
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens] 55 2e-07
gi|168693643 decay accelerating factor for complement isoform 2 ... 54 7e-07
gi|10835143 decay accelerating factor for complement isoform 1 p... 54 7e-07
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 54 9e-07
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 54 9e-07
gi|167830411 natriuretic peptide receptor 1 [Homo sapiens] 54 9e-07
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ... 53 2e-06
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ... 52 3e-06
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs... 52 3e-06
gi|148886654 polydom [Homo sapiens] 52 3e-06
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 52 3e-06
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 52 3e-06
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 52 3e-06
gi|37577159 calcium-sensing receptor [Homo sapiens] 50 8e-06
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 50 1e-05
gi|4505441 natriuretic peptide receptor C/guanylate cyclase C (a... 49 2e-05
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre... 49 2e-05
>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
precursor [Homo sapiens]
Length = 961
Score = 1959 bits (5076), Expect = 0.0
Identities = 961/961 (100%), Positives = 961/961 (100%)
Query: 1 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD 60
MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
Sbjct: 1 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD 60
Query: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP 120
YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
Sbjct: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP 120
Query: 121 ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG 180
ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
Sbjct: 121 ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG 180
Query: 181 GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI 240
GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
Sbjct: 181 GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI 240
Query: 241 ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL 300
ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
Sbjct: 241 ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL 300
Query: 301 FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR 360
FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
Sbjct: 301 FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR 360
Query: 361 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE 420
IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
Sbjct: 361 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE 420
Query: 421 GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA 480
GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
Sbjct: 421 GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA 480
Query: 481 LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE 540
LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
Sbjct: 481 LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE 540
Query: 541 QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS 600
QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
Sbjct: 541 QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS 600
Query: 601 LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP 660
LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
Sbjct: 601 LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP 660
Query: 661 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM 720
FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
Sbjct: 661 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM 720
Query: 721 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL 780
DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
Sbjct: 721 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL 780
Query: 781 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA 840
LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
Sbjct: 781 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA 840
Query: 841 IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK 900
IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
Sbjct: 841 IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK 900
Query: 901 IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY 960
IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
Sbjct: 901 IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY 960
Query: 961 K 961
K
Sbjct: 961 K 961
>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
precursor [Homo sapiens]
Length = 899
Score = 1632 bits (4225), Expect = 0.0
Identities = 810/837 (96%), Positives = 817/837 (97%), Gaps = 2/837 (0%)
Query: 127 VDFRCDPDFHLVGSS-RSICSQGQWST-PKPHCQVNRTPHSERRAVYIGALFPMSGGWPG 184
+++ C + +VG R + G W+ P VNRTPHSERRAVYIGALFPMSGGWPG
Sbjct: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVNRTPHSERRAVYIGALFPMSGGWPG 122
Query: 185 GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMP 244
GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMP
Sbjct: 123 GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMP 182
Query: 245 GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW 304
GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW
Sbjct: 183 GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW 242
Query: 305 GWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVG 364
GWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVG
Sbjct: 243 GWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVG 302
Query: 365 LFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT 424
LFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT
Sbjct: 303 LFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT 362
Query: 425 TEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKT 484
TEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKT
Sbjct: 363 TEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKT 422
Query: 485 SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQG 544
SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQG
Sbjct: 423 SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQG 482
Query: 545 GSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIV 604
GSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIV
Sbjct: 483 GSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIV 542
Query: 605 LAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQ 664
LAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQ
Sbjct: 543 LAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQ 602
Query: 665 ARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLT 724
ARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLT
Sbjct: 603 ARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLT 662
Query: 725 LAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLG 784
LAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLG
Sbjct: 663 LAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLG 722
Query: 785 IFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFS 844
IFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFS
Sbjct: 723 IFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFS 782
Query: 845 SYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAE 904
SYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAE
Sbjct: 783 SYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAE 842
Query: 905 KEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK 961
KEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
Sbjct: 843 KEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK 899
Score = 207 bits (527), Expect = 4e-53
Identities = 97/97 (100%), Positives = 97/97 (100%)
Query: 1 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD 60
MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
Sbjct: 1 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD 60
Query: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCV 97
YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCV
Sbjct: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCV 97
>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
precursor [Homo sapiens]
Length = 844
Score = 1623 bits (4204), Expect = 0.0
Identities = 802/809 (99%), Positives = 804/809 (99%)
Query: 153 PKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELK 212
P+PH +V P SERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELK
Sbjct: 36 PRPHSRVPPHPSSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELK 95
Query: 213 LIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSP 272
LIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSP
Sbjct: 96 LIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSP 155
Query: 273 ALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE 332
ALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE
Sbjct: 156 ALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE 215
Query: 333 AGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFL 392
AGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFL
Sbjct: 216 AGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFL 275
Query: 393 IGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTK 452
IGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTK
Sbjct: 276 IGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTK 335
Query: 453 RLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRA 512
RLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRA
Sbjct: 336 RLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRA 395
Query: 513 MNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGS 572
MNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGS
Sbjct: 396 MNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGS 455
Query: 573 PPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNL 632
PPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNL
Sbjct: 456 PPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNL 515
Query: 633 TAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVF 692
TAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVF
Sbjct: 516 TAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVF 575
Query: 693 TKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDV 752
TKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDV
Sbjct: 576 TKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDV 635
Query: 753 SILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNV 812
SILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNV
Sbjct: 636 SILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNV 695
Query: 813 AVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD 872
AVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD
Sbjct: 696 AVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD 755
Query: 873 TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPP 932
TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPP
Sbjct: 756 TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPP 815
Query: 933 EPSGGLPRGPPEPPDRLSCDGSRVHLLYK 961
EPSGGLPRGPPEPPDRLSCDGSRVHLLYK
Sbjct: 816 EPSGGLPRGPPEPPDRLSCDGSRVHLLYK 844
>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
Length = 941
Score = 473 bits (1216), Expect = e-133
Identities = 269/754 (35%), Positives = 425/754 (56%), Gaps = 31/754 (4%)
Query: 185 GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMP 244
G+ PAVE+A+E + + +L Y L L +D++CD + K Y+ + P +++
Sbjct: 74 GRGVLPAVELAIEQIRNE-SLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFG 132
Query: 245 G-CSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEK 303
G C SV++++AE+ + WNL+ LS+ +++P L++++++P FFRT PS NP +KL +
Sbjct: 133 GVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKH 192
Query: 304 WGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIV 363
+ WK++ T+ Q + F+ +DL + IEI+ +SF +DP VK LK D RII+
Sbjct: 193 YQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIIL 252
Query: 364 GLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSIN---CTVDEMTEAVE 420
G F + A KVFC Y+E ++G KY W + GWY +W++ N C + A+E
Sbjct: 253 GQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAME 312
Query: 421 GHITTEIVMLNPANTRSISNMTSQEFVEKLT-KRLKRHPEETGGFQEAPLAYDAIWALAL 479
G+I + L+ ++IS T Q++ + KR P + G+ AYD IW +A
Sbjct: 313 GYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGY-----AYDGIWVIAK 367
Query: 480 ALNKTSGGGGRSG--VRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWT 537
L + S R++DFNY + T+ I AMN ++F GV+G VVF +G RM
Sbjct: 368 TLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVF-RNGERMGTI 426
Query: 538 LIEQLQGGSYKKIGYYDSTKDDLSW-SKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVS 596
Q Q K+G Y++ D L + T ++ G PP D+T++++ R +S L+ +S
Sbjct: 427 KFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILS 486
Query: 597 VLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGR 656
L+ LG+++A L FNI N + + I+ S P +NNL +G L+ A++F GLDG +
Sbjct: 487 ALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSE 546
Query: 657 NQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGL 716
F +C R W+L +G++ +G+MF K W VH +F + KK K ++ KL VG
Sbjct: 547 KTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKK---KIIKDQKLLVIVGG 603
Query: 717 LVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 776
++ +D+ L WQ VDPL RT+E ++ E D+SI P LEHC + M WLGI Y Y
Sbjct: 604 MLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAY 663
Query: 777 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAF 836
KGLL+L G FLA+ET++VS +ND + +GM++YNV ++C+I A V+ + Q + F
Sbjct: 664 KGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCI 723
Query: 837 ASLAIVFSSYITLVVLFVPKMRRLITRGE----------WQSEAQDTMKTGSS-TNNNEE 885
+L I+F S ITL ++FVPK+ L T + Q++ ++ KT +S T+ N+
Sbjct: 724 VALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQA 783
Query: 886 EKSRL--LEKENRELEKIIAEKEERVSELRHQLQ 917
SRL L+ EN L I E ++ + E+ QLQ
Sbjct: 784 STSRLEGLQSENHRLRMKITELDKDLEEVTMQLQ 817
>gi|23308585 G protein-coupled receptor 156 [Homo sapiens]
Length = 814
Score = 119 bits (297), Expect = 2e-26
Identities = 100/386 (25%), Positives = 176/386 (45%), Gaps = 14/386 (3%)
Query: 582 KTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLAL 641
KT LS L V S G++L + L+F I+ R ++ S PNLN +T +G L
Sbjct: 40 KTISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTY 99
Query: 642 AAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEW 701
++ + G+ +G + + Q RL +L +G SL +G + K W ++ VFT++ K
Sbjct: 100 SSAYLFGIQDVLVGSSMETLI-QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDK-- 156
Query: 702 RKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEH- 760
R ++ +L V L+ DV+ L W + DP+ + ++ + DVS H
Sbjct: 157 RVIIKDLQLLGLVAALLMADVILLMTWVLTDPI-QCLQILSVSMTVTGKDVSCTSTSTHF 215
Query: 761 CSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITA 820
C+SR + W+ + +G KGLLLL G +LA T VS+ +N + + + + + +
Sbjct: 216 CASRYSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLF 275
Query: 821 PVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 880
VT L S + F S I + +F+P++++ E + K S+
Sbjct: 276 VVTRYLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTP 335
Query: 881 NNN-----EEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQ--LRSRRHPPTPPE 933
N + EE++ E +E+++ EK + L+ Q+ + ++ +R T
Sbjct: 336 NKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDL 395
Query: 934 PSGGLPRGPPEPPDRLSCDGSRVHLL 959
P G P P P++ + VH L
Sbjct: 396 PEGAAP--PASSPNKDVQAVASVHTL 419
>gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]
Length = 1047
Score = 65.5 bits (158), Expect = 2e-10
Identities = 94/421 (22%), Positives = 164/421 (38%), Gaps = 66/421 (15%)
Query: 190 PAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYEL------LYNDPIKIILM 243
PAV +A+E + + +L+ + + + G ++YL L LY+DP ++L
Sbjct: 47 PAVALAVEALGRALPV----DLRFVSSELE---GACSEYLAPLSAVDLKLYHDP-DLLLG 98
Query: 244 PGCSSVSTLVAEAARMWNLIVLSYGSSSPALS-NRQRFPTFFRTHPSATLHNPTRVKLFE 302
PGC + VA A W L +L+ G+ + S + T RT PSA V L
Sbjct: 99 PGCVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHG 158
Query: 303 KWGWKKIATI-----QQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVP--VKNLK 355
+ W A + + T++ + E ++ + + + Q + +P P +
Sbjct: 159 HFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQ-HQVYAREPGGPEQATHFI 217
Query: 356 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADN-----WFKIYDPSINC 410
R + RI+ ++ + +E L YV+F + + ++ P +
Sbjct: 218 RANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDN 277
Query: 411 TVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAP-- 468
E +A+ T +V+ R N QEF +L R + E G + P
Sbjct: 278 RTREQAQALREAFQTVLVI----TYREPPNPEYQEFQNRLLIRAR----EDFGVELGPSL 329
Query: 469 ------LAYDAIWALALALNKT--SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEG 520
YD I A LN+T GG G+R I M + G
Sbjct: 330 MNLIAGCFYDGILLYAEVLNETIQEGGTREDGLR--------------IVEKMQGRRYHG 375
Query: 521 VSGHVVFDASGSR----MAWTLIEQLQGGSYKKIGYYDSTKDDLSWS-KTDKWIGGSPPA 575
V+G VV D + R + W + L G ++ +Y + + W+ + W+ G+PP+
Sbjct: 376 VTGLVVMDKNNDRETDFVLWAM-GDLDSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPS 434
Query: 576 D 576
D
Sbjct: 435 D 435
>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
Length = 912
Score = 65.1 bits (157), Expect = 3e-10
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 10/198 (5%)
Query: 663 CQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDV 722
C R LGLG S+ Y ++ TK ++ +F + + + + P A L+ + +
Sbjct: 652 CSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQL 711
Query: 723 LTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLL 782
L + +W +VDP H ++ + + +D + C ++ L GY LL++
Sbjct: 712 LGICVWFVVDPSHSVVDF----QDQRTLDPRFARGVLKCDISDLS--LICLLGYSMLLMV 765
Query: 783 LGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF---AFASL 839
A +T+ V E N+ + +G +Y ++ L P+ S D + ++
Sbjct: 766 TCTVYAIKTRGV-PETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTV 824
Query: 840 AIVFSSYITLVVLFVPKM 857
++ S+ ++L +L++PK+
Sbjct: 825 SVSLSASVSLGMLYMPKV 842
Score = 52.0 bits (123), Expect = 3e-06
Identities = 63/295 (21%), Positives = 122/295 (41%), Gaps = 50/295 (16%)
Query: 170 VYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDYEL--KLIHH 216
+ +G LFP+ G G+ C A+ AL+ +N+ D+LP+ L +++
Sbjct: 49 ITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDT 108
Query: 217 DSKCDPG--QATKYLYELLYND----------------PIKIILMPGCS--SVSTLVAEA 256
S+ Q+ ++ L+ D P +++ + G S SVS +VA
Sbjct: 109 CSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANI 168
Query: 257 ARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTT 316
R++ + +SY S++P LS+ R+ F R PS T V + W ++T+
Sbjct: 169 LRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEG 228
Query: 317 EVFTSTLDDLEERVKEAG-------IEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYET 369
S ++ ++ +E G ++I + + L+ +AR ++ E
Sbjct: 229 SYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANED 288
Query: 370 EARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT 424
+ R+V + G +F +G +D+W P ++ + E EG +T
Sbjct: 289 DIRRVLEAARRANQTGH---FFWMG--SDSWGSKIAPVLH-----LEEVAEGAVT 333
>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
[Homo sapiens]
Length = 908
Score = 59.7 bits (143), Expect = 1e-08
Identities = 51/242 (21%), Positives = 103/242 (42%), Gaps = 22/242 (9%)
Query: 662 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 721
+C R LGLG Y ++ TK +H +F + ++ K + P L+ +
Sbjct: 647 ICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQ 706
Query: 722 VLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 776
+L + +W +VDP H I+ T E+ + + I CS GY
Sbjct: 707 LLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICS-----------LGY 755
Query: 777 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF-- 834
LL++ A +T+ V E N+ + +G +Y ++ L P+ + + +
Sbjct: 756 SILLMVTCTVYAIKTRGV-PETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQ 814
Query: 835 -AFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEK 893
++++ S+ ++L +L++PK+ +I E Q ++ + +S+L++K
Sbjct: 815 TTTLTVSMSLSASVSLGMLYMPKVYIIIFHPE--QNVQKRKRSFKAVVTAATMQSKLIQK 872
Query: 894 EN 895
N
Sbjct: 873 GN 874
Score = 49.7 bits (117), Expect = 1e-05
Identities = 47/196 (23%), Positives = 85/196 (43%), Gaps = 17/196 (8%)
Query: 236 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP 295
D I ++ SSVS +VA R++ + +SY S++P LS+ R+ F R P +
Sbjct: 145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ 204
Query: 296 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE-AGIEITFRQSFFSDP------A 348
V + GW ++T+ S ++ + +E G+ I Q +P
Sbjct: 205 AMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEK 264
Query: 349 VPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSI 408
+ + L+ +AR ++ E + R++ E K+ ++W IG +D+W P
Sbjct: 265 IIKRLLETPNARAVIMFANEDDIRRIL-EAAKKLNQSGHFLW--IG--SDSWGSKIAP-- 317
Query: 409 NCTVDEMTEAVEGHIT 424
V + E EG +T
Sbjct: 318 ---VYQQEEIAEGAVT 330
>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
[Homo sapiens]
Length = 908
Score = 59.7 bits (143), Expect = 1e-08
Identities = 51/242 (21%), Positives = 103/242 (42%), Gaps = 22/242 (9%)
Query: 662 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 721
+C R LGLG Y ++ TK +H +F + ++ K + P L+ +
Sbjct: 647 ICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQ 706
Query: 722 VLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 776
+L + +W +VDP H I+ T E+ + + I CS GY
Sbjct: 707 LLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICS-----------LGY 755
Query: 777 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF-- 834
LL++ A +T+ V E N+ + +G +Y ++ L P+ + + +
Sbjct: 756 SILLMVTCTVYAIKTRGV-PETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQ 814
Query: 835 -AFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEK 893
++++ S+ ++L +L++PK+ +I E Q ++ + +S+L++K
Sbjct: 815 TTTLTVSMSLSASVSLGMLYMPKVYIIIFHPE--QNVQKRKRSFKAVVTAATMQSKLIQK 872
Query: 894 EN 895
N
Sbjct: 873 GN 874
Score = 49.7 bits (117), Expect = 1e-05
Identities = 47/196 (23%), Positives = 85/196 (43%), Gaps = 17/196 (8%)
Query: 236 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP 295
D I ++ SSVS +VA R++ + +SY S++P LS+ R+ F R P +
Sbjct: 145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ 204
Query: 296 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE-AGIEITFRQSFFSDP------A 348
V + GW ++T+ S ++ + +E G+ I Q +P
Sbjct: 205 AMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEK 264
Query: 349 VPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSI 408
+ + L+ +AR ++ E + R++ E K+ ++W IG +D+W P
Sbjct: 265 IIKRLLETPNARAVIMFANEDDIRRIL-EAAKKLNQSGHFLW--IG--SDSWGSKIAP-- 317
Query: 409 NCTVDEMTEAVEGHIT 424
V + E EG +T
Sbjct: 318 ---VYQQEEIAEGAVT 330
>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
Length = 852
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 191 AVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK----------------YLYELLY 234
A++MA+E++N++ D+LP L D+ +P A K Y Y
Sbjct: 75 AMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQY 134
Query: 235 NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHN 294
+ ++ P S ++ + + + + +SYG+S LS R+ FP+FFRT PS +
Sbjct: 135 QPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQL 194
Query: 295 PTRVKLFEKWGWKKIATIQQTTE 317
+L +++GW +A + E
Sbjct: 195 TAAAELLQEFGWNWVAALGSDDE 217
>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
[Homo sapiens]
Length = 922
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/208 (25%), Positives = 88/208 (42%), Gaps = 37/208 (17%)
Query: 163 PHSERRA--VYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 209
PHS R V +G LFP+ P G C A+ AL+ +NS ++LP+
Sbjct: 40 PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99
Query: 210 ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 247
L D+ C Q+ ++ L+ D P K++ + G S
Sbjct: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158
Query: 248 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 306
SVS +VA R++ + +SY S++P LS+ +R+ F R P + V + + GW
Sbjct: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218
Query: 307 KKIATIQQTTEVFTSTLDDLEERVKEAG 334
++T+ ++ + KEAG
Sbjct: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)
Query: 598 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 657
L+ LGI+ + ++ I + ++ S L+ + G L F + I +
Sbjct: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650
Query: 658 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 717
VC R LGLG + Y ++ TK ++ +F + ++ + + P A L
Sbjct: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709
Query: 718 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 772
+ + +L + IW VDP + I+ T E+ + + I CS
Sbjct: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759
Query: 773 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 832
GY LL++ A +T+ V E N+ + +G +Y ++ L P+ + +
Sbjct: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817
Query: 833 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 865
+ ++++ S+ + L +L++PK+ +I E
Sbjct: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853
>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
[Homo sapiens]
Length = 915
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/208 (25%), Positives = 88/208 (42%), Gaps = 37/208 (17%)
Query: 163 PHSERRA--VYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 209
PHS R V +G LFP+ P G C A+ AL+ +NS ++LP+
Sbjct: 40 PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99
Query: 210 ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 247
L D+ C Q+ ++ L+ D P K++ + G S
Sbjct: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158
Query: 248 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 306
SVS +VA R++ + +SY S++P LS+ +R+ F R P + V + + GW
Sbjct: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218
Query: 307 KKIATIQQTTEVFTSTLDDLEERVKEAG 334
++T+ ++ + KEAG
Sbjct: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)
Query: 598 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 657
L+ LGI+ + ++ I + ++ S L+ + G L F + I +
Sbjct: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650
Query: 658 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 717
VC R LGLG + Y ++ TK ++ +F + ++ + + P A L
Sbjct: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709
Query: 718 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 772
+ + +L + IW VDP + I+ T E+ + + I CS
Sbjct: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759
Query: 773 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 832
GY LL++ A +T+ V E N+ + +G +Y ++ L P+ + +
Sbjct: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817
Query: 833 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 865
+ ++++ S+ + L +L++PK+ +I E
Sbjct: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853
>gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]
Length = 841
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 24/222 (10%)
Query: 191 AVEMALEDVNSRRDILPDYELKLIHHDSKCD-------------PGQATKYLY-ELLYND 236
A+ + +E++N+ +LP+ L +D D PGQ L +LL+
Sbjct: 78 AMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYS 137
Query: 237 PIKIILMPGCSSVSTLVAEAARMWNLIV--LSYGSSSPALSNRQRFPTFFRTHPSATLHN 294
P ++ + G S + AA + +V +SY +SS LS ++++P+F RT P+
Sbjct: 138 PT-VLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQV 196
Query: 295 PTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVP---- 350
T V L +K+GW I+ + + + + LE + GI I F+ V
Sbjct: 197 ETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERM 256
Query: 351 ---VKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYV 389
+++L + A ++V AR F V L GK +V
Sbjct: 257 QCLMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWV 298
>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
Length = 480
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 24/222 (10%)
Query: 191 AVEMALEDVNSRRDILPDYELKLIHHDSKCD-------------PGQATKYLY-ELLYND 236
A+ + +E++N+ +LP+ L +D D PGQ L +LL+
Sbjct: 78 AMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYS 137
Query: 237 PIKIILMPGCSSVSTLVAEAARMWNLIV--LSYGSSSPALSNRQRFPTFFRTHPSATLHN 294
P ++ + G S + AA + +V +SY +SS LS ++++P+F RT P+
Sbjct: 138 PT-VLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQV 196
Query: 295 PTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVP---- 350
T V L +K+GW I+ + + + + LE + GI I F+ V
Sbjct: 197 ETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERM 256
Query: 351 ---VKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYV 389
+++L + A ++V AR F V L GK +V
Sbjct: 257 QCLMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWV 298
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 53.9 bits (128), Expect = 7e-07
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 21/115 (18%)
Query: 55 NFLPVDYEIEYVCR-GEREV--VGPKVRKCLANGSWTDMDTPSRCVRICSKSYLT----L 107
N+ PV +EY CR G R + PK+ CL N W S V C K +
Sbjct: 117 NYFPVGTVVEYECRPGYRREPSLSPKLT-CLQNLKW------STAVEFCKKKSCPNPGEI 169
Query: 108 ENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSIC----SQGQWSTPKPHCQ 158
NG++ + GG L GA + F C+ + L GS+ S C S QWS P P C+
Sbjct: 170 RNGQIDVPGG---ILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 221
Score = 31.6 bits (70), Expect = 3.7
Identities = 25/109 (22%), Positives = 41/109 (37%), Gaps = 23/109 (21%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTP-SRCVRICSKSYLTLENGKVFLTGGDLPA 121
I + C ++ G CL +GS P C I + ++NG
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG----------I 235
Query: 122 LDGAR--------VDFRCDPDFHLVGSSRSICS----QGQWSTPKPHCQ 158
+ G R V + C+ F ++G C+ +G+WS P P C+
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 53.9 bits (128), Expect = 7e-07
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 21/115 (18%)
Query: 55 NFLPVDYEIEYVCR-GEREV--VGPKVRKCLANGSWTDMDTPSRCVRICSKSYLT----L 107
N+ PV +EY CR G R + PK+ CL N W S V C K +
Sbjct: 117 NYFPVGTVVEYECRPGYRREPSLSPKLT-CLQNLKW------STAVEFCKKKSCPNPGEI 169
Query: 108 ENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSIC----SQGQWSTPKPHCQ 158
NG++ + GG L GA + F C+ + L GS+ S C S QWS P P C+
Sbjct: 170 RNGQIDVPGG---ILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 221
Score = 31.6 bits (70), Expect = 3.7
Identities = 25/109 (22%), Positives = 41/109 (37%), Gaps = 23/109 (21%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTP-SRCVRICSKSYLTLENGKVFLTGGDLPA 121
I + C ++ G CL +GS P C I + ++NG
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG----------I 235
Query: 122 LDGAR--------VDFRCDPDFHLVGSSRSICS----QGQWSTPKPHCQ 158
+ G R V + C+ F ++G C+ +G+WS P P C+
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 53.5 bits (127), Expect = 9e-07
Identities = 144/738 (19%), Positives = 280/738 (37%), Gaps = 136/738 (18%)
Query: 237 PIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPT 296
PI ++ PG SSV+ V +++N+ ++Y ++S LS++ F F R PS
Sbjct: 142 PIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARA 201
Query: 297 RVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNL 354
V + +++ W ++ + S ++ ++ + GI I +S+ K L
Sbjct: 202 MVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL 261
Query: 355 KRQDARIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYD 405
K+ + + +AR V FCE + R G + L+G +D W YD
Sbjct: 262 KKLTSHL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD 312
Query: 406 PSINCTVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTK 452
D G IT ++ + L P N QEF + +
Sbjct: 313 -----VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQC 365
Query: 453 RLKRHPEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGV 493
RL+ P+E + Q++ + + +AI+++A L+ + S G +G+
Sbjct: 366 RLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGL 425
Query: 494 RLEDFNYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----Y 547
+ + + + + + ++F GVSG ++FD +G S + ++ + G Y
Sbjct: 426 CDAMKPIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDY 481
Query: 548 KKIGYYDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFR 585
+G +D+ + DD WSK I S P ++ + K
Sbjct: 482 INVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE 541
Query: 586 FLSQKLFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVR 620
++ + L S +V A + L ++ + V
Sbjct: 542 YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVF 601
Query: 621 YIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGS 680
I P + + + C + LA + L + + C + +GL ++ Y +
Sbjct: 602 IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA 661
Query: 681 MFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIET 740
+ TK + + ++K +K P + A L++ ++ + + IV
Sbjct: 662 LVTKTNRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------AL 711
Query: 741 FAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEK 798
F E P D P + T LG+ GY GLL+L F A++T++V
Sbjct: 712 FIMEPPDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-N 767
Query: 799 INDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMR 858
N+ + + +Y ++ L P+ S+ + F ++ S+ + L +FVPK+
Sbjct: 768 FNEAKYIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVY 823
Query: 859 RLITRGEWQSEAQDTMKT 876
++ + E + T T
Sbjct: 824 IILAKPERNVRSAFTTST 841
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 53.5 bits (127), Expect = 9e-07
Identities = 144/738 (19%), Positives = 280/738 (37%), Gaps = 136/738 (18%)
Query: 237 PIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPT 296
PI ++ PG SSV+ V +++N+ ++Y ++S LS++ F F R PS
Sbjct: 142 PIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARA 201
Query: 297 RVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNL 354
V + +++ W ++ + S ++ ++ + GI I +S+ K L
Sbjct: 202 MVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL 261
Query: 355 KRQDARIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYD 405
K+ + + +AR V FCE + R G + L+G +D W YD
Sbjct: 262 KKLTSHL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD 312
Query: 406 PSINCTVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTK 452
D G IT ++ + L P N QEF + +
Sbjct: 313 -----VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQC 365
Query: 453 RLKRHPEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGV 493
RL+ P+E + Q++ + + +AI+++A L+ + S G +G+
Sbjct: 366 RLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGL 425
Query: 494 RLEDFNYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----Y 547
+ + + + + + ++F GVSG ++FD +G S + ++ + G Y
Sbjct: 426 CDAMKPIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDY 481
Query: 548 KKIGYYDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFR 585
+G +D+ + DD WSK I S P ++ + K
Sbjct: 482 INVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE 541
Query: 586 FLSQKLFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVR 620
++ + L S +V A + L ++ + V
Sbjct: 542 YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVF 601
Query: 621 YIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGS 680
I P + + + C + LA + L + + C + +GL ++ Y +
Sbjct: 602 IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA 661
Query: 681 MFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIET 740
+ TK + + ++K +K P + A L++ ++ + + IV
Sbjct: 662 LVTKTNRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------AL 711
Query: 741 FAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEK 798
F E P D P + T LG+ GY GLL+L F A++T++V
Sbjct: 712 FIMEPPDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-N 767
Query: 799 INDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMR 858
N+ + + +Y ++ L P+ S+ + F ++ S+ + L +FVPK+
Sbjct: 768 FNEAKYIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVY 823
Query: 859 RLITRGEWQSEAQDTMKT 876
++ + E + T T
Sbjct: 824 IILAKPERNVRSAFTTST 841
>gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]
Length = 1061
Score = 53.5 bits (127), Expect = 9e-07
Identities = 89/416 (21%), Positives = 155/416 (37%), Gaps = 50/416 (12%)
Query: 190 PAVEMALEDVNSRRDILPDYELKLIHHDSK-----CDPGQATKYLYELLYNDPIKIILMP 244
PAVE+AL V +R D+LP + ++ + S+ C A +L + + L P
Sbjct: 57 PAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGP 116
Query: 245 GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW 304
GC + V W + +L+ G+ + + + R PS L +
Sbjct: 117 GCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRL 176
Query: 305 GWKKIATIQQT-----TEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKR--- 356
GW++ A + E ++ L RV++ F D L R
Sbjct: 177 GWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMP 236
Query: 357 QDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMT 416
+ R+I R + + L G+ YV+F + + + P+
Sbjct: 237 RKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPR----RPW 292
Query: 417 EAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK-------RHPEETGGFQEAPL 469
E +G + A + + + E++E L K+LK E G P
Sbjct: 293 ERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFL-KQLKHLAYEQFNFTMEDGLVNTIPA 351
Query: 470 AY-DAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITD--QIYRAMNSSSFEGVSGHVV 526
++ D + A+ +T GG T+TD I + M + SF+GV+G++
Sbjct: 352 SFHDGLLLYIQAVTETLAHGG--------------TVTDGENITQRMWNRSFQGVTGYLK 397
Query: 527 FDASGSR----MAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDK--WIGGSPPAD 576
D+SG R W + + G+++ + Y+ T +L K W G PP D
Sbjct: 398 IDSSGDRETDFSLWDM--DPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPD 451
>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
sapiens]
Length = 877
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/287 (19%), Positives = 116/287 (40%), Gaps = 17/287 (5%)
Query: 597 VLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGR 656
+L+ LGIV ++ + ++ ++ S L+ + G L A F + +
Sbjct: 591 LLAVLGIVATTTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAE------ 644
Query: 657 NQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGL 716
VC AR LGLG +L Y ++ TK ++ +F + + + P
Sbjct: 645 -PGAAVCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFS 703
Query: 717 LVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 776
L + V+ + W P H I+ E + +D + C ++ +G GY
Sbjct: 704 LTSLQVVGMIAWLGARPPHSVID----YEEQRTVDPEQARGVLKCDMSDLSL-IGCL-GY 757
Query: 777 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF-- 834
LL++ A + + V E N+ + +G +Y ++ L P+ + + +
Sbjct: 758 SLLLMVTCTVYAIKARGV-PETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQ 816
Query: 835 -AFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 880
++++ S+ ++L +L+VPK ++ E + + +ST
Sbjct: 817 TTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKATST 863
Score = 47.0 bits (110), Expect = 9e-05
Identities = 47/201 (23%), Positives = 83/201 (41%), Gaps = 38/201 (18%)
Query: 172 IGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDYEL--KLIHHDS 218
+G LFP+ G+AC A+ AL+ VN+ ++LP L +L+ S
Sbjct: 41 LGGLFPVHARGAAGRACGQLKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCS 100
Query: 219 KCDPG--QATKYLYELLYN---------------------DPIKIILMPGCS--SVSTLV 253
+ QA ++ L+ P +++ + G S SVS +V
Sbjct: 101 RDTYALEQALSFVQALIRGRGDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMV 160
Query: 254 AEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQ 313
A R++ + +SY S++P LS+ R+ F R P + V + GW ++T+
Sbjct: 161 ANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLA 220
Query: 314 QTTEVFTSTLDDLEERVKEAG 334
S ++ + +EAG
Sbjct: 221 SEGNYGESGVEAFVQISREAG 241
>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
sapiens]
Length = 254
Score = 52.0 bits (123), Expect = 3e-06
Identities = 47/200 (23%), Positives = 82/200 (41%), Gaps = 12/200 (6%)
Query: 662 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 721
VC R LG FS+ Y ++ TK + +F E + + + P A L+
Sbjct: 13 VCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQ 72
Query: 722 VLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLL 781
+L + W +V+ KE E +V L C+ R + LG Y LL+
Sbjct: 73 LLIVVAWLVVE-----APGTGKETAPERREVVTL----RCNHRDA-SMLGSL-AYNVLLI 121
Query: 782 LLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAI 841
L A++T+ E N+ + +G +Y ++ L P+ + SS +++
Sbjct: 122 ALCTLYAFKTRK-CPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSV 180
Query: 842 VFSSYITLVVLFVPKMRRLI 861
S + L LF PK+ ++
Sbjct: 181 SLSGSVVLGCLFAPKLHIIL 200
>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
[Homo sapiens]
Length = 872
Score = 52.0 bits (123), Expect = 3e-06
Identities = 47/200 (23%), Positives = 82/200 (41%), Gaps = 12/200 (6%)
Query: 662 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 721
VC R LG FS+ Y ++ TK + +F E + + + P A L+
Sbjct: 631 VCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQ 690
Query: 722 VLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLL 781
+L + W +V+ KE E +V L C+ R + LG Y LL+
Sbjct: 691 LLIVVAWLVVE-----APGTGKETAPERREVVTL----RCNHRDA-SMLGSL-AYNVLLI 739
Query: 782 LLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAI 841
L A++T+ E N+ + +G +Y ++ L P+ + SS +++
Sbjct: 740 ALCTLYAFKTRK-CPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSV 798
Query: 842 VFSSYITLVVLFVPKMRRLI 861
S + L LF PK+ ++
Sbjct: 799 SLSGSVVLGCLFAPKLHIIL 818
Score = 39.7 bits (91), Expect = 0.014
Identities = 42/187 (22%), Positives = 78/187 (41%), Gaps = 18/187 (9%)
Query: 247 SSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 306
S VS VA R++ + +SY S+S LS++ R+ F RT P ++ + W
Sbjct: 145 SDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNW 204
Query: 307 KKIATIQQTTEVFTSTLD--DLEERVKEAGI----EITFRQSFFSDPAVPVKNLKRQDAR 360
++T+ + + ++ +LE R + + ++ S + V L++ AR
Sbjct: 205 TYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSAR 264
Query: 361 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE 420
+ V +AR++ +RL + W +D W ++ V A E
Sbjct: 265 VAVLFTRSEDARELLAA--SQRL-NASFTWVA----SDGW-----GALESVVAGSEGAAE 312
Query: 421 GHITTEI 427
G IT E+
Sbjct: 313 GAITIEL 319
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C + GP CL G W D+D PS C I S +ENG F+ G D
Sbjct: 2520 VTYSCNRGFRLEGPSALTCLETGDW-DVDAPS-CNAIHCDSPQPIENG--FVEGADYSY- 2574
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHC 157
GA + + C P F + G + C + WS+ P C
Sbjct: 2575 -GAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTC 2608
Score = 50.1 bits (118), Expect = 1e-05
Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 8/97 (8%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
I+Y C ++ G R+CL+NGSW+ +PS C+ C S +E G V G D
Sbjct: 2971 IQYQCFPGYKLHGNSSRRCLSNGSWSG-SSPS-CLP-CRCSTPVIEYGTV--NGTDFDCG 3025
Query: 123 DGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQ 158
AR+ +C F L+G S C + GQWS+ PHC+
Sbjct: 3026 KAARI--QCFKGFKLLGLSEITCEADGQWSSGFPHCE 3060
Score = 46.6 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
++ C ++VG V+ CL G WT C RI LENG F + D A
Sbjct: 1653 KVNLFCDPGFQLVGNPVQYCLNQGQWTQ--PLPHCERISCGVPPPLENG--FHSADDFYA 1708
Query: 122 LDGARVDFRCDPDFHLVGSSRSICS-QGQWSTPKPHC 157
G+ V ++C+ ++L+G SR C+ G W+ P C
Sbjct: 1709 --GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1743
Score = 46.2 bits (108), Expect = 1e-04
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 12/71 (16%)
Query: 97 VRICSKSYLTLENGKVFLTGGDLPAL--------DGARVDFRCDPDFHLVGSSRSIC-SQ 147
V+I SKS + ++ GG +P L G++V+ CDP F LVG+ C +Q
Sbjct: 1619 VKIDSKSIFCSDCPRL---GGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQ 1675
Query: 148 GQWSTPKPHCQ 158
GQW+ P PHC+
Sbjct: 1676 GQWTQPLPHCE 1686
Score = 44.3 bits (103), Expect = 6e-04
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
E+ Y C + VG V C AN W ++P CV + ++NG F+ G +
Sbjct: 2226 EVRYQCNPGYKSVGSPVFVCQANRHW-HSESPLMCVPLDCGKPPPIQNG--FMKGENFEV 2282
Query: 122 LDGARVDFRCDPDFHLVGSSRSICSQ-GQWS-TPKPHCQVNRTP 163
G++V F C+ + LVG S C + G+W+ P C + P
Sbjct: 2283 --GSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCP 2324
Score = 43.9 bits (102), Expect = 7e-04
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
++ Y C + G K CLAN SW+ +P C + S + NGK L+G L
Sbjct: 1868 KVTYRCNKGYTLAGDKESSCLANSSWS--HSPPVCEPVKCSSPENINNGKYILSG--LTY 1923
Query: 122 LDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQV 159
L A + CD + L G S C + G W P C +
Sbjct: 1924 LSTA--SYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1960
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/149 (22%), Positives = 56/149 (37%), Gaps = 18/149 (12%)
Query: 10 LFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRG 69
L + G P+ S C + P G +R+ + ++Y C+
Sbjct: 2697 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSA-----------VQYSCKP 2745
Query: 70 EREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDF 129
+ G +R CL N W+ RC I K + NG + G + L + + +
Sbjct: 2746 GHILAGSDLRLCLENRKWS--GASPRCEAISCKKPNPVMNGSI--KGSNYTYL--STLYY 2799
Query: 130 RCDPDFHLVGSSRSICSQGQ-WSTPKPHC 157
CDP + L G+ R C + W +P C
Sbjct: 2800 ECDPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/98 (34%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
EIEY C + G + R CLANGSW+ TP CV + + L NG G D
Sbjct: 2854 EIEYTCNEGFLLEGARSRVCLANGSWSGA-TPD-CVPVRCATPPQLANG--VTEGLDYGF 2909
Query: 122 LDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQ 158
+ V F C + L G+ + C S G W P C+
Sbjct: 2910 M--KEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK 2945
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 80 KCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVG 139
+C+ G W +C+ + ++ NG + +G + GA V + C+ F++ G
Sbjct: 2125 ECMRGGQWNPSPMSIQCIPVRCGEPPSIMNG--YASGSNYSF--GAMVAYSCNKGFYIKG 2180
Query: 140 SSRSIC-SQGQWSTPKPHC 157
+S C + GQWS+P P C
Sbjct: 2181 EKKSTCEATGQWSSPIPTC 2199
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 12/108 (11%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ + C+ + GP V KCL + W D P + +C+ L G +P+
Sbjct: 2345 VTFSCKEGHVLQGPSVLKCLPSQQWND-SFPVCKIVLCTPPPL-------ISFGVPIPSS 2396
Query: 123 D---GARVDFRCDPDFHLVGSSRSICS-QGQWSTPKPHCQVNRTPHSE 166
G+ V + C F L G+S ++C G WS+P P C P E
Sbjct: 2397 ALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPE 2444
Score = 41.6 bits (96), Expect = 0.004
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 7/97 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C E++G V C +G+W PS C+ I ENG + T +
Sbjct: 2681 VSYTCNPGYELLGNPVLICQEDGTWNG-SAPS-CISIECDLPTAPENGFLRFTETSM--- 2735
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQG-QWSTPKPHCQ 158
G+ V + C P L GS +C + +WS P C+
Sbjct: 2736 -GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCE 2771
Score = 40.8 bits (94), Expect = 0.006
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Query: 59 VDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGD 118
V E+ + C+ +++G CL +G W + + V C K + ENG + +
Sbjct: 1807 VGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS-CGKPAIP-ENGCI----EE 1860
Query: 119 LPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQ 158
L G++V +RC+ + L G S C + WS P C+
Sbjct: 1861 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCE 1901
Score = 40.0 bits (92), Expect = 0.010
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 15/106 (14%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSY----LTLENGKVFLTGGD 118
I Y C E+ G + R C N W S V IC ++ L NGK +
Sbjct: 3263 IIYQCEPGYELEGNRERVCQENRQW------SGGVAICKETRCETPLEFLNGKADIEN-- 3314
Query: 119 LPALDGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHCQVNRTP 163
G V + C+ + L G S + C++ G WS P P C+ N P
Sbjct: 3315 --RTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCP 3358
Score = 37.7 bits (86), Expect = 0.052
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 7/97 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
++Y C G + G C +G+W+ CV + + NG + + G L L
Sbjct: 2404 VKYSCVGGFFLRGNSTTLCQPDGTWSS--PLPECVPVECPQPEEIPNGIIDVQG--LAYL 2459
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHCQ 158
A + C P F LVG++ ++C + G W KP C+
Sbjct: 2460 STAL--YTCKPGFELVGNTTTLCGENGHWLGGKPTCK 2494
Score = 37.0 bits (84), Expect = 0.089
Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 130 RCDPDFHLVGSSRSIC-SQGQWSTPKPHCQVNRTPH 164
RC P F LVGSS +C G WS + +C+V PH
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPH 440
Score = 35.4 bits (80), Expect = 0.26
Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 5/92 (5%)
Query: 67 CRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGAR 126
C ++VG + CL NG W+ ++ R VR C ++G + + ++ L
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCR-VRTC-PHLRQPKHGHISCSTREM--LYKTT 461
Query: 127 VDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
CD + L GS + C QW P+P C
Sbjct: 462 CLVACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 32.3 bits (72), Expect = 2.2
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 7/97 (7%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
E+ + C + G C ++G+W D + P C + L +G F G
Sbjct: 2912 EVTFHCHEGYILHGAPKLTCQSDGNW-DAEIPL-CKPVNCGPPEDLAHG--FPNGFSF-- 2965
Query: 122 LDGARVDFRCDPDFHLVG-SSRSICSQGQWSTPKPHC 157
+ G + ++C P + L G SSR S G WS P C
Sbjct: 2966 IHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC 3002
Score = 31.2 bits (69), Expect = 4.9
Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 11/100 (11%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C+ + G +CLA+G W+ D +C+ + +++ + L
Sbjct: 1985 VTYTCKEGYTLAGLDTIECLADGKWSRSD--QQCLAVSCDEPPIVDHA----SPETAHRL 2038
Query: 123 DGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPK----PHC 157
G + C + L +S+ +C +QG+W P+ P C
Sbjct: 2039 FGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2078
Score = 31.2 bits (69), Expect = 4.9
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C + G K C A G W+ P+ C + +ENG + T G +
Sbjct: 2168 VAYSCNKGFYIKGEKKSTCEATGQWSS-PIPT-CHPVSCGEPPKVENGFLEHTTG---RI 2222
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQGQ-WSTPKP 155
+ V ++C+P + VGS +C + W + P
Sbjct: 2223 FESEVRYQCNPGYKSVGSPVFVCQANRHWHSESP 2256
Score = 31.2 bits (69), Expect = 4.9
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 14/104 (13%)
Query: 59 VDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENG---KVFLT 115
VD + CR + G + C + +WT T ++C +I +EN V
Sbjct: 3376 VDQNVSIKCREGFLLQGHGIITCNPDETWTQ--TSAKCEKISCGPPAHVENAIARGVHYQ 3433
Query: 116 GGDLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQ 158
GD+ + + C + L G RS+C G W++P P C+
Sbjct: 3434 YGDM-------ITYSCYSGYMLEGFLRSVCLENGTWTSP-PICR 3469
Score = 30.8 bits (68), Expect = 6.4
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 122 LDGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHC 157
L G V + C+P + L+G+ IC + G W+ P C
Sbjct: 2676 LYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 2712
Score = 30.8 bits (68), Expect = 6.4
Identities = 21/104 (20%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 59 VDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGD 118
V+ ++ C G + C +G+W + C + + E+G F+ G
Sbjct: 3199 VNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHG--FVVGSK 3256
Query: 119 LPALDGARVDFRCDPDFHLVGSSRSICSQG-QWSTPKPHCQVNR 161
+ + ++C+P + L G+ +C + QWS C+ R
Sbjct: 3257 YTF--ESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETR 3298
Score = 30.4 bits (67), Expect = 8.3
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 7/110 (6%)
Query: 51 VKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENG 110
+K NF V ++++ C E+VG C +G W P C + L LEN
Sbjct: 2275 MKGENF-EVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPL-LENQ 2332
Query: 111 KVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQV 159
V +L G V F C L G S C QW+ P C++
Sbjct: 2333 LVL---KELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2378
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 51.6 bits (122), Expect = 3e-06
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 13/101 (12%)
Query: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLE---NGKVFLTGG 117
+ I Y+C E+ P V C+ NG+W+ + P + C + + GK F+
Sbjct: 3213 FSISYICSPGYELSFPAVLTCVGNGTWSG-EVPQCLPKFCGDPGIPAQGKREGKSFIYQS 3271
Query: 118 DLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
+ V F C+ F LVGSS IC + G WS PHC
Sbjct: 3272 E--------VSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3304
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 73 VVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCD 132
+VG VR+CL++G W++ +T RC+ + NG+V G + D V ++C+
Sbjct: 2751 LVGSAVRECLSSGLWSESET--RCLAGHCGIPELIVNGQVI--GENYGYRD--TVVYQCN 2804
Query: 133 PDFHLVGSSRSICSQG-QWSTPKPHC 157
P F L+GSS IC Q WS P C
Sbjct: 2805 PGFRLIGSSVRICQQDHNWSGQLPSC 2830
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 19/150 (12%)
Query: 17 AGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGP 76
A A P + C I P GGI LT D + V + Y C +
Sbjct: 2579 AWDAPVPACQAISCGIPKAPTNGGI----LTTDYL-------VGTRVTYFCNDGYRLSSK 2627
Query: 77 KVRK--CLANGSWTDMDTPSRCVRICSKSY--LTLENGKVFLTGGDLPALDGARVDFRCD 132
++ C ++G+W++ + RCV + S LE+G+ + G +V F CD
Sbjct: 2628 ELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYK-TKVVFSCD 2686
Query: 133 PDFHLVGSSRSIC-SQGQWS--TPKPHCQV 159
P +H +G + C G WS +P+CQ+
Sbjct: 2687 PGYHGLGPASIECLPNGTWSWRNERPYCQI 2716
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C + G + R CLANGSWT + V+ + T NGKVF G
Sbjct: 3038 VRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG--TTANGKVFRIDG---TT 3092
Query: 123 DGARVDFRCDPDFHLVGSS-RSICSQGQWSTPKPHCQV 159
+ V + C + L G S R + G WS P+C +
Sbjct: 3093 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3130
Score = 40.0 bits (92), Expect = 0.010
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
++ + C +GP +CL NG+W+ + C I T NG T
Sbjct: 2680 KVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY-- 2737
Query: 122 LDGARVDFRCDPDFHLVGSS-RSICSQGQWSTPKPHC 157
G+ F CD F LVGS+ R S G WS + C
Sbjct: 2738 --GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772
Score = 37.7 bits (86), Expect = 0.052
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 75 GPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPD 134
GP +C AN W+ + V + + G+ G V + C+P
Sbjct: 2869 GPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--GTVVFYDCNPG 2926
Query: 135 FHLVGSSRSICS-QGQWSTPKPHC 157
+ L GSS IC GQW P P C
Sbjct: 2927 YFLFGSSVLICQPNGQWDKPLPEC 2950
Score = 37.4 bits (85), Expect = 0.068
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
Query: 59 VDYEIEYVCRG--EREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTG 116
V + Y+C+ E+ G ++R C NG+W+ + R V + ++ NG++ T
Sbjct: 3151 VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS--NGRLEGTN 3208
Query: 117 GDLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
D G + + C P + L + C G WS P C
Sbjct: 3209 FDW----GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3246
Score = 33.9 bits (76), Expect = 0.75
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 113 FLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQG---QWSTPKPHCQ 158
F+ G D G + F C P + L+G+S C G W+ P P C+
Sbjct: 2194 FVIGNDFTV--GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
Score = 33.5 bits (75), Expect = 0.98
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 9/49 (18%)
Query: 115 TGGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQ-----WSTPKPHCQ 158
TGG L ++ V + CD F LVG S ++C + W P P CQ
Sbjct: 2544 TGGQLNSV----VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Score = 31.6 bits (70), Expect = 3.7
Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 7/99 (7%)
Query: 65 YVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDG 124
Y C + G V C NG W D P + C + L+G G
Sbjct: 2921 YDCNPGYFLFGSSVLICQPNGQW-DKPLPECIMIDCGHPGVP---PNAVLSGEKYTF--G 2974
Query: 125 ARVDFRCDPDFHLVGSSRSICS-QGQWSTPKPHCQVNRT 162
+ V + C L+G S C G WS +PHC + T
Sbjct: 2975 STVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDAT 3013
Score = 30.8 bits (68), Expect = 6.4
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 9/57 (15%)
Query: 108 ENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQ-----GQWSTPKPHCQV 159
ENGK G D G+ V F CD D+ L G+ C + WS +P C+V
Sbjct: 453 ENGKRI--GSDFSL--GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Score = 30.8 bits (68), Expect = 6.4
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C ++G VR C + +W+ PS CV + + G+ G + +
Sbjct: 2799 VVYQCNPGFRLIGSSVRICQQDHNWSGQ-LPS-CVPVSCGHPGSPIYGRTSGNGFNFNDV 2856
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQG-QWSTPKPHCQV 159
V F C+ + + G +++ C QWS P P C+V
Sbjct: 2857 ----VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2890
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 51.6 bits (122), Expect = 3e-06
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 13/101 (12%)
Query: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLE---NGKVFLTGG 117
+ I Y+C E+ P V C+ NG+W+ + P + C + + GK F+
Sbjct: 3084 FSISYICSPGYELSFPAVLTCVGNGTWSG-EVPQCLPKFCGDPGIPAQGKREGKSFIYQS 3142
Query: 118 DLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
+ V F C+ F LVGSS IC + G WS PHC
Sbjct: 3143 E--------VSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3175
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 73 VVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCD 132
+VG VR+CL++G W++ +T RC+ + NG+V G + D V ++C+
Sbjct: 2622 LVGSAVRECLSSGLWSESET--RCLAGHCGIPELIVNGQVI--GENYGYRD--TVVYQCN 2675
Query: 133 PDFHLVGSSRSICSQG-QWSTPKPHC 157
P F L+GSS IC Q WS P C
Sbjct: 2676 PGFRLIGSSVRICQQDHNWSGQLPSC 2701
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C + G + R CLANGSWT + V+ + T NGKVF G
Sbjct: 2909 VRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG--TTANGKVFRIDG---TT 2963
Query: 123 DGARVDFRCDPDFHLVGSS-RSICSQGQWSTPKPHCQV 159
+ V + C + L G S R + G WS P+C +
Sbjct: 2964 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3001
Score = 44.3 bits (103), Expect = 6e-04
Identities = 41/144 (28%), Positives = 56/144 (38%), Gaps = 18/144 (12%)
Query: 17 AGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGP 76
A A P + C I P GGI LT D + V + Y C +
Sbjct: 2515 AWDAPVPACQAISCGIPKAPTNGGI----LTTDYL-------VGTRVTYFCNDGYRLSSK 2563
Query: 77 KVRK--CLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPD 134
++ C ++G+W++ + RCV I T NG T G+ F CD
Sbjct: 2564 ELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSY----GSTAIFTCDLG 2619
Query: 135 FHLVGSS-RSICSQGQWSTPKPHC 157
F LVGS+ R S G WS + C
Sbjct: 2620 FMLVGSAVRECLSSGLWSESETRC 2643
Score = 37.7 bits (86), Expect = 0.052
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 75 GPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPD 134
GP +C AN W+ + V + + G+ G V + C+P
Sbjct: 2740 GPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--GTVVFYDCNPG 2797
Query: 135 FHLVGSSRSICS-QGQWSTPKPHC 157
+ L GSS IC GQW P P C
Sbjct: 2798 YFLFGSSVLICQPNGQWDKPLPEC 2821
Score = 37.4 bits (85), Expect = 0.068
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
Query: 59 VDYEIEYVCRG--EREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTG 116
V + Y+C+ E+ G ++R C NG+W+ + R V + ++ NG++ T
Sbjct: 3022 VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS--NGRLEGTN 3079
Query: 117 GDLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
D G + + C P + L + C G WS P C
Sbjct: 3080 FDW----GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117
Score = 33.9 bits (76), Expect = 0.75
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 113 FLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQG---QWSTPKPHCQ 158
F+ G D G + F C P + L+G+S C G W+ P P C+
Sbjct: 2130 FVIGNDFTV--GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
Score = 33.5 bits (75), Expect = 0.98
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 9/49 (18%)
Query: 115 TGGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQ-----WSTPKPHCQ 158
TGG L ++ V + CD F LVG S ++C + W P P CQ
Sbjct: 2480 TGGQLNSV----VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Score = 31.6 bits (70), Expect = 3.7
Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 7/99 (7%)
Query: 65 YVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDG 124
Y C + G V C NG W D P + C + L+G G
Sbjct: 2792 YDCNPGYFLFGSSVLICQPNGQW-DKPLPECIMIDCGHPGVP---PNAVLSGEKYTF--G 2845
Query: 125 ARVDFRCDPDFHLVGSSRSICS-QGQWSTPKPHCQVNRT 162
+ V + C L+G S C G WS +PHC + T
Sbjct: 2846 STVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDAT 2884
Score = 30.8 bits (68), Expect = 6.4
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 9/57 (15%)
Query: 108 ENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQ-----GQWSTPKPHCQV 159
ENGK G D G+ V F CD D+ L G+ C + WS +P C+V
Sbjct: 389 ENGKRI--GSDFSL--GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 441
Score = 30.8 bits (68), Expect = 6.4
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C ++G VR C + +W+ PS CV + + G+ G + +
Sbjct: 2670 VVYQCNPGFRLIGSSVRICQQDHNWSGQ-LPS-CVPVSCGHPGSPIYGRTSGNGFNFNDV 2727
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQG-QWSTPKPHCQV 159
V F C+ + + G +++ C QWS P P C+V
Sbjct: 2728 ----VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2761
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 51.6 bits (122), Expect = 3e-06
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 13/101 (12%)
Query: 61 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLE---NGKVFLTGG 117
+ I Y+C E+ P V C+ NG+W+ + P + C + + GK F+
Sbjct: 3253 FSISYICSPGYELSFPAVLTCVGNGTWSG-EVPQCLPKFCGDPGIPAQGKREGKSFIYQS 3311
Query: 118 DLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
+ V F C+ F LVGSS IC + G WS PHC
Sbjct: 3312 E--------VSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3344
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 73 VVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCD 132
+VG VR+CL++G W++ +T RC+ + NG+V G + D V ++C+
Sbjct: 2791 LVGSAVRECLSSGLWSESET--RCLAGHCGIPELIVNGQVI--GENYGYRD--TVVYQCN 2844
Query: 133 PDFHLVGSSRSICSQG-QWSTPKPHC 157
P F L+GSS IC Q WS P C
Sbjct: 2845 PGFRLIGSSVRICQQDHNWSGQLPSC 2870
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 19/150 (12%)
Query: 17 AGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGP 76
A A P + C I P GGI LT D + V + Y C +
Sbjct: 2619 AWDAPVPACQAISCGIPKAPTNGGI----LTTDYL-------VGTRVTYFCNDGYRLSSK 2667
Query: 77 KVRK--CLANGSWTDMDTPSRCVRICSKSY--LTLENGKVFLTGGDLPALDGARVDFRCD 132
++ C ++G+W++ + RCV + S LE+G+ + G +V F CD
Sbjct: 2668 ELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYK-TKVVFSCD 2726
Query: 133 PDFHLVGSSRSIC-SQGQWS--TPKPHCQV 159
P +H +G + C G WS +P+CQ+
Sbjct: 2727 PGYHGLGPASIECLPNGTWSWRNERPYCQI 2756
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C + G + R CLANGSWT + V+ + T NGKVF G
Sbjct: 3078 VRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG--TTANGKVFRIDG---TT 3132
Query: 123 DGARVDFRCDPDFHLVGSS-RSICSQGQWSTPKPHCQV 159
+ V + C + L G S R + G WS P+C +
Sbjct: 3133 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3170
Score = 40.0 bits (92), Expect = 0.010
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA 121
++ + C +GP +CL NG+W+ + C I T NG T
Sbjct: 2720 KVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY-- 2777
Query: 122 LDGARVDFRCDPDFHLVGSS-RSICSQGQWSTPKPHC 157
G+ F CD F LVGS+ R S G WS + C
Sbjct: 2778 --GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2812
Score = 37.7 bits (86), Expect = 0.052
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 75 GPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPD 134
GP +C AN W+ + V + + G+ G V + C+P
Sbjct: 2909 GPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--GTVVFYDCNPG 2966
Query: 135 FHLVGSSRSICS-QGQWSTPKPHC 157
+ L GSS IC GQW P P C
Sbjct: 2967 YFLFGSSVLICQPNGQWDKPLPEC 2990
Score = 37.4 bits (85), Expect = 0.068
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
Query: 59 VDYEIEYVCRG--EREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTG 116
V + Y+C+ E+ G ++R C NG+W+ + R V + ++ NG++ T
Sbjct: 3191 VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS--NGRLEGTN 3248
Query: 117 GDLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
D G + + C P + L + C G WS P C
Sbjct: 3249 FDW----GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3286
Score = 33.9 bits (76), Expect = 0.75
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 113 FLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQG---QWSTPKPHCQ 158
F+ G D G + F C P + L+G+S C G W+ P P C+
Sbjct: 2234 FVIGNDFTV--GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2280
Score = 33.5 bits (75), Expect = 0.98
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 9/49 (18%)
Query: 115 TGGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQ-----WSTPKPHCQ 158
TGG L ++ V + CD F LVG S ++C + W P P CQ
Sbjct: 2584 TGGQLNSV----VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Score = 31.6 bits (70), Expect = 3.7
Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 7/99 (7%)
Query: 65 YVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDG 124
Y C + G V C NG W D P + C + L+G G
Sbjct: 2961 YDCNPGYFLFGSSVLICQPNGQW-DKPLPECIMIDCGHPGVP---PNAVLSGEKYTF--G 3014
Query: 125 ARVDFRCDPDFHLVGSSRSICS-QGQWSTPKPHCQVNRT 162
+ V + C L+G S C G WS +PHC + T
Sbjct: 3015 STVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDAT 3053
Score = 30.8 bits (68), Expect = 6.4
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 9/57 (15%)
Query: 108 ENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQ-----GQWSTPKPHCQV 159
ENGK G D G+ V F CD D+ L G+ C + WS +P C+V
Sbjct: 493 ENGKRI--GSDFSL--GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Score = 30.8 bits (68), Expect = 6.4
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C ++G VR C + +W+ PS CV + + G+ G + +
Sbjct: 2839 VVYQCNPGFRLIGSSVRICQQDHNWSGQ-LPS-CVPVSCGHPGSPIYGRTSGNGFNFNDV 2896
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQG-QWSTPKPHCQV 159
V F C+ + + G +++ C QWS P P C+V
Sbjct: 2897 ----VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2930
>gi|37577159 calcium-sensing receptor [Homo sapiens]
Length = 1078
Score = 50.4 bits (119), Expect = 8e-06
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 7/149 (4%)
Query: 247 SSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 306
S VST VA ++ + +SY SSS LSN+ +F +F RT P+ + E + W
Sbjct: 147 SGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRW 206
Query: 307 KKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQ--SFFSDPAV---PVKNLKRQDARI 361
+ TI + ++ E +E I I F + S +SD V+ ++ A++
Sbjct: 207 NWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKV 266
Query: 362 IVGLFYETEARKVFCEVYKERLFGKKYVW 390
IV + + E+ + + GK +W
Sbjct: 267 IVVFSSGPDLEPLIKEIVRRNITGK--IW 293
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 50.1 bits (118), Expect = 1e-05
Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 65 YVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDG 124
+ C +VG VR+CLANG W+ +T RC+ S + NG + +G D
Sbjct: 2647 FTCNTGYTLVGSHVRECLANGLWSGSET--RCLAGHCGSPDPIVNGHI--SGDGFSYRD- 2701
Query: 125 ARVDFRCDPDFHLVGSSRSICSQG-QWSTPKPHC 157
V ++C+P F LVG+S IC Q +WS P C
Sbjct: 2702 -TVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2734
Score = 45.1 bits (105), Expect = 3e-04
Identities = 35/98 (35%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ Y C +VG VR CL + W+ TP CV I +G F G +
Sbjct: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQ-TPV-CVPITCGHPGNPAHG--FTNGSEFNLN 2758
Query: 123 DGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQV 159
D V+F C+ + L G SR+ C S GQWS+P P C+V
Sbjct: 2759 DV--VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRV 2794
Score = 36.2 bits (82), Expect = 0.15
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 7/99 (7%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
I Y C+ ++G C+ANG W D P C + LTG
Sbjct: 2824 ILYHCKKGFYLLGSSALTCMANGLW-DRSLPKCLAISCGHPGVP---ANAVLTGELFTY- 2878
Query: 123 DGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHCQVN 160
GA V + C L+G+ +C + WS PHC N
Sbjct: 2879 -GAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGN 2916
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 67 CRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGAR 126
CR + G R CLAN +W+ + T C+ + T + V DLP G
Sbjct: 3244 CRKGYHIQGSTTRTCLANLTWSGIQT--ECIPHACRQPETPAHADV--RAIDLPTF-GYT 3298
Query: 127 VDFRCDPDFHLVGSS--RSICSQGQWSTPKPHCQ 158
+ + C P F L G S R+ + +W+ P C+
Sbjct: 3299 LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
Score = 35.0 bits (79), Expect = 0.34
Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 13/99 (13%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLE---NGKVFLTGGDL 119
I Y C ++ + C G W + P C + E +GK F +
Sbjct: 3120 ISYSCMDGYQLSHSAILSCEGRGVWKG-EIPQCLPVFCGDPGIPAEGRLSGKSFTYKSE- 3177
Query: 120 PALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHC 157
V F+C F LVGSSR +C + G WS +P C
Sbjct: 3178 -------VFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3209
Score = 34.7 bits (78), Expect = 0.44
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
Query: 75 GPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPD 134
G ++ +C ANG+W D C I S NG T + GA F C+
Sbjct: 2597 GWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGT----LTVYGATAIFTCNTG 2652
Query: 135 FHLVGSS-RSICSQGQWSTPKPHC 157
+ LVGS R + G WS + C
Sbjct: 2653 YTLVGSHVRECLANGLWSGSETRC 2676
Score = 33.5 bits (75), Expect = 0.98
Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 39/131 (29%)
Query: 62 EIEYVCRGEREVVGPKVRKCLANGSWT---------------DMDTPSRCVRICSKSYLT 106
E+ + C+ +VG R C A+G+W+ D TP ++ S+ Y
Sbjct: 3177 EVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEV 3236
Query: 107 LENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSIC-SQGQWSTPK----PH-CQVN 160
G+ V FRC +H+ GS+ C + WS + PH C+
Sbjct: 3237 -----------------GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQP 3279
Query: 161 RTP-HSERRAV 170
TP H++ RA+
Sbjct: 3280 ETPAHADVRAI 3290
Score = 32.7 bits (73), Expect = 1.7
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 6/98 (6%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ + C ++ G R CL NGSW+ + C + + T NG + + G L
Sbjct: 2943 LRFSCEMGHQLRGSPERTCLLNGSWSGLQPV--CEAVSCGNPGTPTNGMIVSSDG---IL 2997
Query: 123 DGARVDFRCDPDFHLVG-SSRSICSQGQWSTPKPHCQV 159
+ V + C + G +R + G W+ P C +
Sbjct: 2998 FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTI 3035
Score = 31.6 bits (70), Expect = 3.7
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 9/64 (14%)
Query: 100 CSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQG-----QWSTPK 154
CS ++ G + T G + G++V + C P + +VG S + C + QW +
Sbjct: 2433 CSLTHPLKNGGILNRTAGAV----GSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLT 2488
Query: 155 PHCQ 158
P CQ
Sbjct: 2489 PLCQ 2492
Score = 31.2 bits (69), Expect = 4.9
Identities = 28/118 (23%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
Query: 63 IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 122
+ + C + G +C +NG W+ R V ++ EN +
Sbjct: 2761 VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFV--ENAIRHGQQNFPESF 2818
Query: 123 D-GARVDFRCDPDFHLVGSSRSIC-SQGQWSTPKPHCQVNRTPHS--ERRAVYIGALF 176
+ G + + C F+L+GSS C + G W P C H AV G LF
Sbjct: 2819 EYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELF 2876
Score = 30.8 bits (68), Expect = 6.4
Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Query: 122 LDGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHC 157
L G + F C F LVG C Q QWS KP C
Sbjct: 545 LHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 30.4 bits (67), Expect = 8.3
Identities = 28/116 (24%), Positives = 44/116 (37%), Gaps = 24/116 (20%)
Query: 124 GARVDFRCDPDFHLVGSSRSICSQGQ----WSTPKPHCQV----NRTPHSERRAVYIGAL 175
G V F+CDP + L G ++ C Q W P C N T + V +
Sbjct: 1411 GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPA---GVILSPN 1467
Query: 176 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYE 231
+P +P G+ C V+ + PD+ + LI +P ++YE
Sbjct: 1468 YPQP--YPPGKECDWRVK-----------VNPDFVIALIFKSFNMEPSYDFLHIYE 1510
>gi|4505441 natriuretic peptide receptor C/guanylate cyclase C
(atrionatriuretic peptide receptor C) [Homo sapiens]
Length = 540
Score = 49.3 bits (116), Expect = 2e-05
Identities = 82/387 (21%), Positives = 154/387 (39%), Gaps = 46/387 (11%)
Query: 189 QPAVEMALEDVNS----RRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIK--IIL 242
+PA+E AL V RR + P ++ + DS C + + K +IL
Sbjct: 73 RPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLIL 132
Query: 243 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNR-QRFPTFFRTHPSATLHNPTRVKLF 301
P C + VA A W+L +LS G+ + ++ + R P+ + LF
Sbjct: 133 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALF 192
Query: 302 EKWGWKKIATIQQTTEVFTS---TLDDLEERVKEAGIE---ITFRQSFFSDPAVPVKNLK 355
W + A + ++ + TL+ + E +E G+ +F ++ D V+N++
Sbjct: 193 RHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ 252
Query: 356 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM 415
+ R+++ R + ++ + Y +F I + N D S
Sbjct: 253 ASE-RVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELF--NSSSYGDGSWKRGDKHD 309
Query: 416 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPL------ 469
EA + + + + V ++ EF EK + +K E+ G E +
Sbjct: 310 FEAKQAYSSLQTV--------TLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEG 360
Query: 470 AYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDA 529
+DAI LAL++ R+G +D +I + + +FEG++G V DA
Sbjct: 361 FHDAILLYVLALHEVL----RAGYSKKD--------GGKIIQQTWNRTFEGIAGQVSIDA 408
Query: 530 SGSR---MAWTLIEQLQGGSYKKIGYY 553
+G R + + ++ G+ + IG Y
Sbjct: 409 NGDRYGDFSVIAMTDVEAGTQEVIGDY 435
>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
precursor [Homo sapiens]
Length = 906
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/165 (21%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 182 WPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKII 241
W A + ++E + + S RD D + + PG+ K PI +
Sbjct: 110 WHSSVALEQSIEFIRDSLISIRDE-KDGINRCLPDGQSLPPGRTKK---------PIAGV 159
Query: 242 LMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLF 301
+ PG SSV+ V +++++ ++Y ++S LS++ + F R PS TL + +
Sbjct: 160 IGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIV 219
Query: 302 EKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSD 346
+++ W ++ + S +D +E + G+ I +S+
Sbjct: 220 KRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSN 264
Score = 41.6 bits (96), Expect = 0.004
Identities = 56/312 (17%), Positives = 122/312 (39%), Gaps = 39/312 (12%)
Query: 559 DLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAV-VCLSFNIYNS 617
DL W W + + ++ + + + I+++ S LGI++ + V L F +Y
Sbjct: 566 DLGW-----WPNADLTGCEPIPVRYLEWSNIESIIAIA-FSCLGILVTLFVTLIFVLYRD 619
Query: 618 HVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLG 677
P + + + C + LA +F + + + C + L+GL ++
Sbjct: 620 --------TPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMC 671
Query: 678 YGSMFTKIWWVHTVFTKKEEKKEWRKT--LEPWKLYATVGLLVGMDVLTLAIWQIVDPLH 735
Y ++ TK + + ++K RK + W +L+ + + + I++P
Sbjct: 672 YSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEP-- 729
Query: 736 RTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKS 793
+ + P ++ + LG+ GY GLL++ + A++T++
Sbjct: 730 -------------PMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRN 776
Query: 794 VSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLF 853
V N+ + + +Y ++ L P+ + A+ S + L +F
Sbjct: 777 VPA-NFNEAKYIAFTMYTTCIIWLAFVPIYF----GSNYKIITTCFAVSLSVTVALGCMF 831
Query: 854 VPKMRRLITRGE 865
PKM +I + E
Sbjct: 832 TPKMYIIIAKPE 843
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,727,424
Number of Sequences: 37866
Number of extensions: 1920702
Number of successful extensions: 13261
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 167
Number of HSP's that attempted gapping in prelim test: 11846
Number of HSP's gapped (non-prelim): 1398
length of query: 961
length of database: 18,247,518
effective HSP length: 112
effective length of query: 849
effective length of database: 14,006,526
effective search space: 11891540574
effective search space used: 11891540574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.