Guide to the Human Genome
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Search of human proteins with 239745596

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
         (1731 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]           3497   0.0  
gi|31559825 polycystin 1-like 3 [Homo sapiens]                       3493   0.0  
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo...  3491   0.0  
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo...  3482   0.0  
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]             537   e-152
gi|5174633 receptor for egg jelly-like protein precursor [Homo s...   182   2e-45
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]          179   2e-44
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]          179   3e-44
gi|19923084 polycystin-1L1 [Homo sapiens]                             122   4e-27
gi|4505835 polycystin 2 [Homo sapiens]                                 84   9e-16
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    81   8e-15
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap...    79   4e-14
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap...    79   4e-14
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]          75   6e-13
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]         67   2e-10
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]           58   7e-08
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ...    58   7e-08
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ...    58   7e-08
gi|229093087 G protein-coupled receptor 97 [Homo sapiens]              47   2e-04
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]                  46   3e-04
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi...    45   5e-04
gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi...    45   5e-04
gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi...    45   5e-04
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    44   0.001
gi|44889475 RAB6 interacting protein 1 [Homo sapiens]                  44   0.002
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]             44   0.002
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    42   0.004
gi|224809323 G protein-coupled receptor 56 isoform b precursor [...    42   0.004
gi|224809320 G protein-coupled receptor 56 isoform c precursor [...    42   0.004
gi|224809318 G protein-coupled receptor 56 isoform b precursor [...    42   0.004

>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
          Length = 1731

 Score = 3497 bits (9069), Expect = 0.0
 Identities = 1731/1731 (100%), Positives = 1731/1731 (100%)

Query: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
            MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60

Query: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
            IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120

Query: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
            RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180

Query: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
            GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240

Query: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
            VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300

Query: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
            QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360

Query: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
            LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420

Query: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
            LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480

Query: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
            RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540

Query: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
            LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ
Sbjct: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600

Query: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
            HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660

Query: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
            TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720

Query: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
            KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780

Query: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
            DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840

Query: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
            LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900

Query: 901  TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
            TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901  TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960

Query: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
            NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020

Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
            SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080

Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
            QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140

Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
            GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200

Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260
            ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAPA
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260

Query: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320
            INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ
Sbjct: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320

Query: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380
            FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG
Sbjct: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380

Query: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440
            QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR
Sbjct: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440

Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
            GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN
Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500

Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
            ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL
Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560

Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
            LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR
Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620

Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
            TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE
Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680

Query: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
            RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731


>gi|31559825 polycystin 1-like 3 [Homo sapiens]
          Length = 1732

 Score = 3493 bits (9057), Expect = 0.0
 Identities = 1730/1732 (99%), Positives = 1730/1732 (99%), Gaps = 1/1732 (0%)

Query: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
            MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60

Query: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
            IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120

Query: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
            RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180

Query: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
            GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240

Query: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
            VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300

Query: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
            QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360

Query: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
            LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420

Query: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
            LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480

Query: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
            RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540

Query: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
            LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ
Sbjct: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600

Query: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
            HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660

Query: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
            TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720

Query: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
            KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780

Query: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
            DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840

Query: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
            LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900

Query: 901  TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
            TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901  TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960

Query: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
            NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020

Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
            SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080

Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
            QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140

Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
            GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200

Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENE-XTKRILALLAKCSSSVPGSRDKNNPVYVAP 1259
            ISQPVKVVFFTFLYSLMMSRMPRLNKENE  TKRILALLAKCSSSVPGSRDKNNPVYVAP
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAP 1260

Query: 1260 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1319
            AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH
Sbjct: 1261 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1320

Query: 1320 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1379
            QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE
Sbjct: 1321 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1380

Query: 1380 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1439
            GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM
Sbjct: 1381 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1440

Query: 1440 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1499
            RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR
Sbjct: 1441 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1500

Query: 1500 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1559
            NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV
Sbjct: 1501 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1560

Query: 1560 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1619
            LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY
Sbjct: 1561 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1620

Query: 1620 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1679
            RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK
Sbjct: 1621 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1680

Query: 1680 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
            ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1732


>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
            sapiens]
          Length = 1731

 Score = 3491 bits (9052), Expect = 0.0
 Identities = 1727/1731 (99%), Positives = 1729/1731 (99%)

Query: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
            MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60

Query: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
            IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120

Query: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
            RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180

Query: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
            GHLPTTCHYPLPAHLSKTLCHPISQFPSVL SITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240

Query: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
            VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300

Query: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
            QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360

Query: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
            LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420

Query: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
            LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480

Query: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
            RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540

Query: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
            LEKSLIVSIDPDSPLLMTLYLGFQYQPNCT FHLNITLPKDKVWQKDEEYTW+LNPEHLQ
Sbjct: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600

Query: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
            HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660

Query: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
            TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720

Query: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
            KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780

Query: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
            DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840

Query: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
            LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900

Query: 901  TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
            TR+QRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901  TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960

Query: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
            NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020

Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
            SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080

Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
            QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140

Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
            GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200

Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260
            ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAPA
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260

Query: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320
            INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ
Sbjct: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320

Query: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380
            FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG
Sbjct: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380

Query: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440
            QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR
Sbjct: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440

Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
            GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN
Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500

Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
            ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL
Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560

Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
            LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR
Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620

Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
            TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE
Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680

Query: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
            RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731


>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
            sapiens]
          Length = 1732

 Score = 3482 bits (9030), Expect = 0.0
 Identities = 1724/1732 (99%), Positives = 1727/1732 (99%), Gaps = 1/1732 (0%)

Query: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
            MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1    MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60

Query: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
            IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61   IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120

Query: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
            RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121  RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180

Query: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
            GHLPTTCHYPLPAHLSKTLCHPISQFPSVL SITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181  GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240

Query: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
            VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQ+ASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241  VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQEASGQVIDEIAGNFSRAVHGLQALNKL 300

Query: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
            QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301  QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360

Query: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
            LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361  LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420

Query: 421  LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
            LLSRQNIS+LPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421  LLSRQNISSLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480

Query: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
            RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481  RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540

Query: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
            LEKSLIVSIDPDSPLLMTLYLGFQYQPNCT FHLNITLPKDKVWQKDEEYTWVLNPEHLQ
Sbjct: 541  LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600

Query: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
            HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601  HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660

Query: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
            TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661  TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720

Query: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
            KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721  KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780

Query: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
            DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781  DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840

Query: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
            LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841  LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900

Query: 901  TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
            TR+QRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901  TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960

Query: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
            NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961  NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020

Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
            SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080

Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
            QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140

Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
            GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALY LELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYRLELSKDQATSWMISIILSVLQNIF 1200

Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENE-XTKRILALLAKCSSSVPGSRDKNNPVYVAP 1259
            ISQPVKVVFFTFLYSLMMSRMPRLNKENE  TKRILALLAKCSSSVPGSRDKNNPVYVAP
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAP 1260

Query: 1260 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1319
            AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH
Sbjct: 1261 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1320

Query: 1320 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1379
            QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE
Sbjct: 1321 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1380

Query: 1380 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1439
            GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM
Sbjct: 1381 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1440

Query: 1440 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1499
            RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR
Sbjct: 1441 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1500

Query: 1500 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1559
            NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV
Sbjct: 1501 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1560

Query: 1560 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1619
            LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY
Sbjct: 1561 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1620

Query: 1620 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1679
            RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK
Sbjct: 1621 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1680

Query: 1680 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
            ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1732


>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
          Length = 2459

 Score =  537 bits (1383), Expect = e-152
 Identities = 355/1139 (31%), Positives = 583/1139 (51%), Gaps = 67/1139 (5%)

Query: 248  LAETTSSPKEEGHPNTFTSY-LQVSLQKASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306
            LA+  SS   + H +  +   L + +++   +V + + G+ S    GL+ + ++QE  E 
Sbjct: 898  LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954

Query: 307  LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366
            L+++T  +   +  AQ     +L + SE LL +  +       +   T   F ++ +V +
Sbjct: 955  LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014

Query: 367  AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425
            A   +  E        +    + L+      +  L   + P      L + + ++  +R 
Sbjct: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074

Query: 426  NISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485
               +   SS             P+A +L  L      V+++I     +PF    + ++ G
Sbjct: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134

Query: 486  SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544
            ++G + + S + +L+ V +L E+IEI+L R+    + PT LN+++ +  + VNVTS E +
Sbjct: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193

Query: 545  LIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQHGIG 604
            L + +     + +TL LG+ Y PN + +     L    +   DE  TW+L+P+ L+ G G
Sbjct: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251

Query: 605  TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664
             YY+T V     E A      V + T ++ C +W+   +TW  +GCQVGP+++  +T CL
Sbjct: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311

Query: 665  CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724
            CNHLTFF S F V+   +N+  T +LF    +NPV V+ +  L   YV+ V+WAR+KD  
Sbjct: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371

Query: 725  DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
            D  KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G  EPHHL DP  
Sbjct: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431

Query: 785  TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
             VFERG +D FLL+T   LG L SLRLWHDNSG  PSWYVS+V+V D+ + RKW+FLCN 
Sbjct: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491

Query: 845  WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
            WL++++GDC LD+VF   ++++   F HLF       F   ++W SI +R   + FTRVQ
Sbjct: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551

Query: 905  RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964
            R+SCC +LLLC M+ ++MFW +    A++   +      W E+++ + +++++FPINL+I
Sbjct: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611

Query: 965  GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015
             ++F     Q T P     Q +   D        S +P+   ++  E   K+  R +   
Sbjct: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666

Query: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060
               L        W S    DI  L+ L+  ++   +  GQ   ++ ++            
Sbjct: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726

Query: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106
                         AR  P  ++ +  C YL   L+ ++  L  +G     Q      A  
Sbjct: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784

Query: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166
            QLQ L+  L   + P    P       A  S+ +  KP   GL  W   V WLL+  TS 
Sbjct: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834

Query: 1167 ASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226
             +AFFT LY L   +  +  W+IS+ +S ++++F++QP+KV+ F   ++L++ R+   ++
Sbjct: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD--DE 1892

Query: 1227 ENEXTKRILALLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTGDIL 1285
            E+        LL     ++    R+ +  VY  P   +  K     LK++K F L  +IL
Sbjct: 1893 EDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREIL 1952

Query: 1286 VQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYG 1344
              + FL +L+   Y  ++ + ++L++ +  +F+  FS +   ++F+ WAN  L+ +LYG
Sbjct: 1953 AYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYG 2011



 Score =  203 bits (517), Expect = 1e-51
 Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%)

Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
            G FFT   L+S      +     + + +++IY+L + YY  +QG ++ ++ W +F  K N
Sbjct: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221

Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
            +L+ +IIL S+  L + +K   L ++++ R R+ ++  ISF E    ++A  +++ F VL
Sbjct: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281

Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
            L+TV+LW+LLR +P++ +I+  L RAW ++ GF+++IL +L  Y+IA NL+FG  +  Y+
Sbjct: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341

Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
            T F +A T+V L +GI + EEV    PVLG+FLI + ++ M  VV+NLF+S IL+AF +E
Sbjct: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401

Query: 1681 RK--SLKKEAALIDTLLQKLSNLLGI 1704
            +K   L +E  ++D LL K+ + LGI
Sbjct: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 15/50 (30%), Positives = 28/50 (56%)

Query: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83
          CY+      +F +AQ +C  Q G L  I ++  Q  ++ ++ + ++WWIG
Sbjct: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88


>gi|5174633 receptor for egg jelly-like protein precursor [Homo
            sapiens]
          Length = 2253

 Score =  182 bits (462), Expect = 2e-45
 Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%)

Query: 625  LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666
            LV +     QC         W    C +G +++     C+C                   
Sbjct: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153

Query: 667  -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725
             H  +  +   V+P  V++   + +   +  NPV +  +  ++  YV    WA  +D+ D
Sbjct: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211

Query: 726  MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
               +  V VL DNDP     YL+ ++TG R  + T A V + L G+   S+ H L  P  
Sbjct: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271

Query: 785  TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
            T   RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++  +  W F+C  
Sbjct: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331

Query: 845  WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
            WL+V   D  LDR F      E  + +  F   +     ++++W SI        F R+Q
Sbjct: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388

Query: 905  RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961
            RLSCC+ +LL +++ N+MF+ +N    T ++  + MR        +++ I + +I  P+ 
Sbjct: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441

Query: 962  LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992
            L+I  LF   +  PQ  L    P +   +S+AS
Sbjct: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 70/267 (26%), Positives = 115/267 (43%), Gaps = 24/267 (8%)

Query: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSK 1181
            +EQ PS++         ++ KK     L  W   V W L+  TS  S+FF   Y L    
Sbjct: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604

Query: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK------ENEXTKRIL 1235
            D++  W+ +   S  Q++ + QP K++    L S   +  P+  K      + + T+  L
Sbjct: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660

Query: 1236 ALLAKCSSSVPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFK-----LTGDILVQILF 1290
              +      +    D+   +         T+   R  K+KK  K         IL   +F
Sbjct: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720

Query: 1291 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1350
            L LL+  I   ++++ FY +Q I   FS   + +  L+D Y W N +LLP L+ D     
Sbjct: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779

Query: 1351 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1377
             + E S    G+ L+ Q+ R K+ EK+
Sbjct: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%)

Query: 1435 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1492
            F     G   TS+ L SF+     +K    ++  ++ +I++L    Y   +GC + Q++ 
Sbjct: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991

Query: 1493 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1552
             +     N+L+ ++  I  +L+ L ++   L    +  Y  + + FI F+   +V+    
Sbjct: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051

Query: 1553 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1612
             ++GF + L  ++     R    +R+  R +  A   +     ++ +    Y     L+F
Sbjct: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111

Query: 1613 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1672
            G    +Y     S  TV    +  + Q   F+ + +LG   + + +++M+ V+INLF + 
Sbjct: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170

Query: 1673 ILMAFGKERKSLKKE 1687
            IL A+ + ++ + +E
Sbjct: 2171 ILSAYEEMKQPVYEE 2185


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score =  179 bits (454), Expect = 2e-44
 Identities = 206/850 (24%), Positives = 361/850 (42%), Gaps = 68/850 (8%)

Query: 532  LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590
            L + +N T L+   + S +P+  L   +YL  + +PN  +   +  +  + +   D   Y
Sbjct: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976

Query: 591  TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
            T+ ++P   +   G+Y++      R    Q     VSV    + C Y+   +  W + G 
Sbjct: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030

Query: 651  QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
                +++  +  CL  HLT F +  FV P   R V  E T  +      N + +   A  
Sbjct: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084

Query: 708  LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
            L  Y++      K DQ D  + +           +F Y I V TG+ R + TTA V I L
Sbjct: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142

Query: 768  YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
            YG + RS   HL   +   F R  LD+F + T  SLG++  +R+WHDN G+SP+W++  V
Sbjct: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200

Query: 828  IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
            IV D+   R   FL N WL+V  +     +++  +  S   L  FR L  + +   F   
Sbjct: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260

Query: 886  YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
            ++WLSI  R P ++FTR+QR +CC+ L+   +  N V +  +  +        R   ++ 
Sbjct: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320

Query: 945  SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991
              + V + ++V+++P+ L I  LF            P    Q+ L +   + +S L  + 
Sbjct: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380

Query: 992  -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050
             +   L A   V ++K  + FL    + +     +   S  D+     ++ S +     G
Sbjct: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439

Query: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105
            Q  H  G  E  ++   P +    F      ++Q+ L   + +   TQ  H   D L + 
Sbjct: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499

Query: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159
            S    +  E L    L     PS  +      ++   +  +  GL K     W  S+   
Sbjct: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559

Query: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219
            L       +   +           + +W++S   S L +    +P+KV+     +SL+  
Sbjct: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619

Query: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278
               RL+ + + T      +   S+ VP  R  +   +++A          E   K K+L 
Sbjct: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667

Query: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335
             +   +LV +LFL + + A Y  ++ + + + L  AI  +  S  F  I   ++ +PW  
Sbjct: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727

Query: 1336 HILLPSLYGD 1345
            H+LLP ++G+
Sbjct: 3728 HVLLPYVHGN 3737



 Score = 38.1 bits (87), Expect = 0.075
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596
            RF SF +  +++SAA  L    + L  V+    LR   +  V  +TL RA  E++G  L 
Sbjct: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031

Query: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649
            +++L   YA +A  L+  C  S +    +  V   G  +      E + L P+L
Sbjct: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score =  179 bits (453), Expect = 3e-44
 Identities = 210/855 (24%), Positives = 363/855 (42%), Gaps = 77/855 (9%)

Query: 532  LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590
            L + +N T L+   + S +P+  L   +YL  + +PN  +   +  +  + +   D   Y
Sbjct: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976

Query: 591  TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
            T+ ++P   +   G+Y++      R    Q     VSV    + C Y+   +  W + G 
Sbjct: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030

Query: 651  QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
                +++  +  CL  HLT F +  FV P   R V  E T  +      N + +   A  
Sbjct: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084

Query: 708  LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
            L  Y++      K DQ D  + +           +F Y I V TG+ R + TTA V I L
Sbjct: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142

Query: 768  YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
            YG + RS   HL   +   F R  LD+F + T  SLG++  +R+WHDN G+SP+W++  V
Sbjct: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200

Query: 828  IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
            IV D+   R   FL N WL+V  +     +++  +  S   L  FR L  + +   F   
Sbjct: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260

Query: 886  YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
            ++WLSI  R P ++FTR+QR +CC+ L+   +  N V +  +  +        R   ++ 
Sbjct: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320

Query: 945  SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDAS 992
              + V + ++V+++P+ L I  LF            P    Q+ L +      SCL  + 
Sbjct: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDI-----DSCLDSSV 3375

Query: 993  VEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDIT-KLVKLLS--SLVSSHL- 1048
            ++    T      ++     ++ + +L        W S + T     LLS  S+V S+L 
Sbjct: 3376 LDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLR 3435

Query: 1049 ---EGQGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCD 1100
                GQ  H  G  E  ++   P +    F      ++Q+ L   + +   TQ  H   D
Sbjct: 3436 QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETD 3495

Query: 1101 FLDAASQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLT 1154
             L + S    +  E L    L     PS  +      ++   +  +  GL K     W  
Sbjct: 3496 LLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCA 3555

Query: 1155 SVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLY 1214
            S+   L       +   +           + +W++S   S L +    +P+KV+     +
Sbjct: 3556 SLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYF 3615

Query: 1215 SLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLK 1273
            SL+     RL+ + + T      +   S+ VP  R  +   +++A          E   K
Sbjct: 3616 SLVAK---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARK 3663

Query: 1274 KKKLFKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDF 1330
             K+L  +   +LV +LFL + + A Y  ++ + + + L  AI  +  S  F  I   ++ 
Sbjct: 3664 VKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEEL 3723

Query: 1331 YPWANHILLPSLYGD 1345
            +PW  H+LLP ++G+
Sbjct: 3724 WPWMAHVLLPYVHGN 3738



 Score = 38.1 bits (87), Expect = 0.075
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596
            RF SF +  +++SAA  L    + L  V+    LR   +  V  +TL RA  E++G  L 
Sbjct: 3973 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4032

Query: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649
            +++L   YA +A  L+  C  S +    +  V   G  +      E + L P+L
Sbjct: 4033 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4086


>gi|19923084 polycystin-1L1 [Homo sapiens]
          Length = 2849

 Score =  122 bits (305), Expect = 4e-27
 Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%)

Query: 634  QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693
            +C +W+   + W S      P ++  +  C  + L  FA     +  +  V D  KL   
Sbjct: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747

Query: 694  VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753
              N    + ++ S++  Y   V  +R+ D  + +K     L +        Y + + TG+
Sbjct: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806

Query: 754  RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813
            R  A  T+KV I L G  G SE   L  P+K +FER     F+L+    LG L  +RLWH
Sbjct: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866

Query: 814  DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873
            D+ G SP W++S V+V ++   + W F   CWL+    D  ++R    +       FR L
Sbjct: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924

Query: 874  FSSMIVEKFTQDYLWLSIATRHPWNQFTRVQRLSCCMTLL 913
            F     E     ++WLS+ +R   +++    RL+   +LL
Sbjct: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 28/235 (11%)

Query: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSV 1195
            S  EG  P  S  L  W +S  W + G  SLA +  T   +    ++Q   W+  + LSV
Sbjct: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175

Query: 1196 LQNIFISQPVKVVFFTFLYSLMMSRMPRLNKEN--EXTKRILALLAK---------CSSS 1244
            +  IFI+QP+ V      ++           E+  E T+ + + LA+          S S
Sbjct: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCS 2235

Query: 1245 VPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILFLT 1292
            +P    +   V  A   A +    HP          +R  ++ +      DI + IL L 
Sbjct: 2236 IPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLL 2295

Query: 1293 LLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1343
            LL+  IY   + + + L+QAI K F+         ++ + D++ W+   LL  LY
Sbjct: 2296 LLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350


>gi|4505835 polycystin 2 [Homo sapiens]
          Length = 968

 Score = 84.3 bits (207), Expect = 9e-16
 Identities = 47/221 (21%), Positives = 107/221 (48%), Gaps = 1/221 (0%)

Query: 1469 QVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNM 1528
            ++I+   + YY   +  +++  K  +F    N LD  I+++S + +G+++   S + + +
Sbjct: 477  EIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTS-NVEVL 535

Query: 1529 ARYRDDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWD 1588
             ++ +DQ+ F +F           ++    V    ++L+  +  +  +  +S T+SR   
Sbjct: 536  LQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAK 595

Query: 1589 EVVGFLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPV 1648
            ++ GF ++  I+   YA    L+FG  + D+ TF     T   +++G  +  E+   + V
Sbjct: 596  DLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRV 655

Query: 1649 LGTFLILTSVILMVLVVINLFVSAILMAFGKERKSLKKEAA 1689
            LG     T V  M  +++N+F++ I   + + +  L ++ A
Sbjct: 656  LGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKA 696



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 1271 TLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFY---------LHQAIWKTFSHQF 1321
            T ++K L  +  +++  +LFL +L    Y   +SN +Y         L   + KT    F
Sbjct: 211  TNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNF 270

Query: 1322 SEIKLLQDFYPWANHILLPSLYGDYRGKN 1350
              +  ++DF+ +    LL  LY   +  N
Sbjct: 271  KTLSSMEDFWKFTEGSLLDGLYWKMQPSN 299


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
           sapiens]
          Length = 2211

 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 46/111 (41%), Positives = 66/111 (59%), Gaps = 6/111 (5%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
           Y +   TG  R A T A V ITL+G  G S    L    K+ FE+G +DVF + T  ++G
Sbjct: 45  YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NNVG 103

Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKR---KWHFLCNCWLAVDLGD 852
            ++ +R+ HDN+G++ SWY+  VIV DM  KR   +++F CN WL+   GD
Sbjct: 104 LIYKVRIEHDNTGLNASWYLDHVIVTDM--KRPHLRYYFNCNNWLSKVEGD 152



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803
            Y + V T     A T A V I ++G  G S    L        FER   D F      SL
Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884

Query: 804  GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863
            G+L  LR+WHDN G+ P W++S V V D +    +HF C+CWL+   GD +  R F   +
Sbjct: 1885 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 1944

Query: 864  KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894
             +           +++E      T++ +WL +  R
Sbjct: 1945 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 1979



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 2/113 (1%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
           Y ++VYTG    A T A V I ++G  G +    L + +K  FE+G  D F+L     LG
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRL-ENEKDNFEKGAEDRFILDA-PDLG 231

Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
            L  + + H+N G S  W++SQ+++ D+  KRK+ F  N WLA+D  D ++ R
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDEDDGKIQR 284



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802
            Y +Q++TG    A T AKV IT+YG  G +   +L   + +   FERG  D F++     
Sbjct: 1462 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 1520

Query: 803  LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859
            LG ++ ++L HDNS     WYV +V + +   + ++ FLC  WL++   D  L+R+F
Sbjct: 1521 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLERLF 1577



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 3/122 (2%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSE-GRSEPHHLCDPQKT-VFERGGLDVFLLTTWTS 802
            Y +QV TG    A T A V +T+YG E G +    L    K+  FE+G  D F +     
Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-ID 1082

Query: 803  LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPV 862
            LG L  +R+ HDN+G    W++ ++ + DM  +  ++F C  WLAV+  D +L R  +PV
Sbjct: 1083 LGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEEDDGQLSRELLPV 1142

Query: 863  SK 864
             +
Sbjct: 1143 DE 1144



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 1/108 (0%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
            Y + V TGY   A T A V +T++G+ G +    L    + +FERG  D F L T   LG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 2152

Query: 805  NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGD 852
             L  +RL HD+SG    W V +V V + +      F C  WL    GD
Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 2200



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 5/156 (3%)

Query: 721 KDQADMQKVKVTVLADNDPSAQ-FHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL 779
           KD+ D Q V+  + +D+  + + F Y I + TG    A+T ++V I LYG +  +    L
Sbjct: 661 KDKDDGQLVRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVL 720

Query: 780 C---DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKR 836
               +  K  FERG +D F L T  ++GN++ L + HD++G+  SW++  V +      +
Sbjct: 721 LVSDNNLKDYFERGRVDEFTLET-LNIGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGK 779

Query: 837 KWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRH 872
           ++ F  N WL  +  D  L+    P    E+    H
Sbjct: 780 QYTFPANRWLDKNQADGRLEVELYPSEVVEIQKLVH 815



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 7/127 (5%)

Query: 734  LADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT---VFERG 790
            L   D S  F   I+  TG +++A T A V ITL+G++  +    L    KT    FER 
Sbjct: 1168 LEQKDKSTTFSVTIK--TGVKKNAGTDANVFITLFGTQDDTGMT-LLKSSKTNSDKFERD 1224

Query: 791  GLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDL 850
             +++F + T   LG+L  +RL HDN+G +P W+V  V V   ++ +   F C  WLA + 
Sbjct: 1225 SIEIFTVET-LDLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNE 1283

Query: 851  GDCELDR 857
             D  + R
Sbjct: 1284 DDGSIIR 1290



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 2/92 (2%)

Query: 744 HYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSL 803
           HY ++++TG    A T+A+V + +YG +G++E   L    K VFER   D F L     +
Sbjct: 815 HYEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSK-VFERASKDTFQLEA-ADV 872

Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVK 835
           G ++ LRL H   G  PSW+V  V +  + V+
Sbjct: 873 GEVYKLRLGHTGEGFGPSWFVDTVWLRHLVVR 904



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 2/116 (1%)

Query: 742 QFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWT 801
           +F + + V+T   + A T + + I +YG +GR++   L +P    F+ G ++ F +    
Sbjct: 424 KFPWSLWVWTTDLKKAGTNSPIFIQIYGQKGRTD-EILLNPNNKWFKPGIIEKFRIEL-P 481

Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
            LG  + +R+WHD       W++ ++ + +   K K++F CN WL  +  D E+ R
Sbjct: 482 DLGRFYKIRVWHDKRSSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDDNEIVR 537



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%)

Query: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
           D  K++  +L     +    Y++ V+TG  R A T +K+ + +YG+ G      +   + 
Sbjct: 278 DDGKIQRDILVGGAETTAITYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIF-LEG 336

Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
            VF+RG  D+F +     L  L  + + H N GV+  W+  +V++       +  F C+ 
Sbjct: 337 GVFDRGRTDIFHIELAVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSN 396

Query: 845 WLAVDLGDCELDR 857
           WL     D  ++R
Sbjct: 397 WLDEKKADGLIER 409



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802
           Y + V TG    A T A V + L+G  G +    L  C     +FE+G  D F + + T 
Sbjct: 555 YHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIESVT- 613

Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCD--MAVKRKWHFLCNCWLAVDLGDCELDRVFI 860
           + N+  +R+ HD  G    WY+ +V+V +          F C  WL  D  D +L R  +
Sbjct: 614 MRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKDDGQLVRELL 673

Query: 861 PV-SKRELFSFRHLFS 875
           P  S   L +FR+  S
Sbjct: 674 PSDSSATLKNFRYHIS 689



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSEGR-SEPHHLCD---PQKTVFERGGLDVFLLTTW 800
            Y I +YT    +A T A + I +YG +   ++  +LC     QK  FER     F++   
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 1367

Query: 801  TSLGNLHSLRLWHDNSGVSPSWYVSQV----IVCDMAVKRKWHFLCNCWLAVDLGDCELD 856
                 +  +R+ H+N+G++P W+ S V    ++ D        F C+ WLA    D +  
Sbjct: 1368 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 1427

Query: 857  RVFIP 861
            R  +P
Sbjct: 1428 RELVP 1432



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
            Y + V+TG      T + + +TLYG  G +E   L D +K  FER   D F++     + 
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIA 1755

Query: 805  NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847
                +R+  D  G  P W++ ++++ +M       F    WL+
Sbjct: 1756 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798


>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
           sapiens]
          Length = 1114

 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803
           Y + V T     A T A V I ++G  G S    L        FER   D F      SL
Sbjct: 776 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835

Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863
           G+L  LR+WHDN G+ P W++S V V D +    +HF C+CWL+   GD +  R F   +
Sbjct: 836 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 895

Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894
            +           +++E      T++ +WL +  R
Sbjct: 896 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 930



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802
           Y +Q++TG    A T AKV IT+YG  G +   +L   + +   FERG  D F++     
Sbjct: 351 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 409

Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859
           LG ++ ++L HDNS     WYV +V + +   + ++ FLC  WL++   D  L+R+F
Sbjct: 410 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLERLF 466



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 7/127 (5%)

Query: 734 LADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT---VFERG 790
           L   D S  F   I+  TG +++A T A V ITL+G++  +    L    KT    FER 
Sbjct: 57  LEQKDKSTTFSVTIK--TGVKKNAGTDANVFITLFGTQDDTGMT-LLKSSKTNSDKFERD 113

Query: 791 GLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDL 850
            +++F + T   LG+L  +RL HDN+G +P W+V  V V   ++ +   F C  WLA + 
Sbjct: 114 SIEIFTVET-LDLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNE 172

Query: 851 GDCELDR 857
            D  + R
Sbjct: 173 DDGSIIR 179



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 3/117 (2%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEG-RSEPHHLCDPQ-KTVFERGGLDVFLLTTWTS 802
           Y + V TG  + AAT ++  I L G +  RS+   L  P+ K  F RG ++ F +     
Sbjct: 518 YYVSVTTGKHKDAATDSRAFIFLIGEDDERSKRIWLDYPRGKRGFSRGSVEEFYVAG-LD 576

Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859
           +G +  + L HD +     W V ++ +       K+   CNCWLA D GD    RVF
Sbjct: 577 VGIIKKIELGHDGASPESCWLVEELCLAVPTQGTKYMLNCNCWLAKDRGDGITSRVF 633



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGR-SEPHHLCD---PQKTVFERGGLDVFLLTTW 800
           Y I +YT    +A T A + I +YG +   ++  +LC     QK  FER     F++   
Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 256

Query: 801 TSLGNLHSLRLWHDNSGVSPSWYVSQV----IVCDMAVKRKWHFLCNCWLAVDLGDCELD 856
                +  +R+ H+N+G++P W+ S V    ++ D        F C+ WLA    D +  
Sbjct: 257 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 316

Query: 857 RVFIP 861
           R  +P
Sbjct: 317 RELVP 321



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
           Y + V+TG      T + + +TLYG  G +E   L D +K  FER   D F++     + 
Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIA 706

Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847
               +R+  D  G  P W++ ++++ +M       F    WL+
Sbjct: 707 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 21/55 (38%), Positives = 29/55 (52%)

Query: 745  YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTT 799
            Y + V TGY   A T A V +T++G+ G +    L    + +FERG  D F L T
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET 1099


>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo
           sapiens]
          Length = 512

 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803
           Y + V T     A T A V I ++G  G S    L        FER   D F      SL
Sbjct: 126 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185

Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863
           G+L  LR+WHDN G+ P W++S V V D +    +HF C+CWL+   GD +  R F   +
Sbjct: 186 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 245

Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894
            +           +++E      T++ +WL +  R
Sbjct: 246 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 280



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 1/108 (0%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
           Y + V TGY   A T A V +T++G+ G +    L    + +FERG  D F L T   LG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 453

Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGD 852
            L  +RL HD+SG    W V +V V + +      F C  WL    GD
Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 501



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 749 VYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHS 808
           V+TG      T + + +TLYG  G +E   L D +K  FER   D F++     +     
Sbjct: 3   VWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIAPFTK 60

Query: 809 LRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847
           +R+  D  G  P W++ ++++ +M       F    WL+
Sbjct: 61  MRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99


>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
          Length = 805

 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 54/242 (22%), Positives = 112/242 (46%), Gaps = 13/242 (5%)

Query: 1469 QVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNM 1528
            +VI+ + + YY   +  +L   + R+ +   NILD  +IL+S + +G  +       + M
Sbjct: 356  EVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLM 415

Query: 1529 ARYRDDQD-----RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTL 1583
             +     +      F++F++    N  A +L       A ++++  +  +  +  +S TL
Sbjct: 416  GKLLQQPNTYADFEFLAFWQTQYNNMNAVNL-----FFAWIKIFKYISFNKTMTQLSSTL 470

Query: 1584 SRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVF 1643
            +R   +++GF ++  I+   YA    LLFG  + ++ TF     T   +++G      + 
Sbjct: 471  ARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAID 530

Query: 1644 ALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKERKSL---KKEAALIDTLLQKLSN 1700
              + +LG    +T V  +  V++N+F++ I   + + ++ L   K E  L D L Q  + 
Sbjct: 531  NANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNK 590

Query: 1701 LL 1702
             L
Sbjct: 591  TL 592



 Score = 34.7 bits (78), Expect = 0.83
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 9/84 (10%)

Query: 1269 ERTLKKKKLFKLTG--DILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH------- 1319
            E T + ++L+  T   ++LV I+FL  +    Y   +S+ +Y  + + + F H       
Sbjct: 87   ENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGV 146

Query: 1320 QFSEIKLLQDFYPWANHILLPSLY 1343
             F  I  + DF+ +A   LL SLY
Sbjct: 147  SFQAISSMADFWDFAQGPLLDSLY 170


>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
          Length = 613

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 4/201 (1%)

Query: 1477 CYYAFIQGCQ----LKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYR 1532
            C + F+   Q    +K+ K  +F    N L+  ++L+ F+ +  +          + +  
Sbjct: 290  CIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLL 349

Query: 1533 DDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVG 1592
               +++  FY     +    +++   +  A ++++  +  +  +  +S TLSR   ++VG
Sbjct: 350  KSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVG 409

Query: 1593 FLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTF 1652
            F ++  I+   YA    L+FG  + D+ TF +S      +++G  +   +   +P+LG  
Sbjct: 410  FAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPI 469

Query: 1653 LILTSVILMVLVVINLFVSAI 1673
              +T +  +  V++N+F++ I
Sbjct: 470  YFITFIFFVFFVLLNMFLAII 490


>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
          Length = 1029

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%)

Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767
           FYV    W AR ++  ++ + +  +L+   P      Y + V TG   +A T A V I++
Sbjct: 7   FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65

Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826
           +G +G +    L   + +  F RG  D F L     LG+L  + + HD  G    W++  
Sbjct: 66  HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124

Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
           V++ D     ++ F C+ WL     DC++ R
Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774
           VW   + QAD   V ++ V+          Y + VYTG  + A T ++V + L+G  G S
Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665

Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833
               L      V F+RG +D F +    SLG L  + L  + S  S  WY  QVIV +  
Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724

Query: 834 VKRKWHFLC 842
              +  F C
Sbjct: 725 TTSESIFTC 733


>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
           sapiens]
          Length = 1029

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%)

Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767
           FYV    W AR ++  ++ + +  +L+   P      Y + V TG   +A T A V I++
Sbjct: 7   FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65

Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826
           +G +G +    L   + +  F RG  D F L     LG+L  + + HD  G    W++  
Sbjct: 66  HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124

Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
           V++ D     ++ F C+ WL     DC++ R
Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774
           VW   + QAD   V ++ V+          Y + VYTG  + A T ++V + L+G  G S
Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665

Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833
               L      V F+RG +D F +    SLG L  + L  + S  S  WY  QVIV +  
Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724

Query: 834 VKRKWHFLC 842
              +  F C
Sbjct: 725 TTSESIFTC 733


>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
           sapiens]
          Length = 1029

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%)

Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767
           FYV    W AR ++  ++ + +  +L+   P      Y + V TG   +A T A V I++
Sbjct: 7   FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65

Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826
           +G +G +    L   + +  F RG  D F L     LG+L  + + HD  G    W++  
Sbjct: 66  HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124

Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
           V++ D     ++ F C+ WL     DC++ R
Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774
           VW   + QAD   V ++ V+          Y + VYTG  + A T ++V + L+G  G S
Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665

Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833
               L      V F+RG +D F +    SLG L  + L  + S  S  WY  QVIV +  
Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724

Query: 834 VKRKWHFLC 842
              +  F C
Sbjct: 725 TTSESIFTC 733


>gi|229093087 G protein-coupled receptor 97 [Homo sapiens]
          Length = 549

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 15/90 (16%)

Query: 635 CYYWEIHNQT---WSSAGC--QVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIK 689
           C +W++   T   WSS GC  +V P+ T+    C C+HLTFFA    ++ R    + T+ 
Sbjct: 215 CVFWDVTKGTTGDWSSEGCSTEVRPEGTV----CCCDHLTFFA----LLLRPTLDQSTVH 266

Query: 690 LFLRVTNNPVGVSLLASLLGFYVITVVWAR 719
           +  R++    GVS++   L F +I   + R
Sbjct: 267 ILTRISQAGCGVSMI--FLAFTIILYAFLR 294


>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
          Length = 674

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 26/83 (31%), Positives = 41/83 (49%)

Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
           Y + V TG +  A T   + ++L GS G SE H L  P    FERG +D + +T    LG
Sbjct: 4   YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63

Query: 805 NLHSLRLWHDNSGVSPSWYVSQV 827
            +  +R+      ++  WY+  +
Sbjct: 64  EIQLVRIEKRKYWLNDDWYLKYI 86


>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo
           sapiens]
          Length = 1079

 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%)

Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690
           C +W+         WS  GCQ    S     QCLC HLT F+    + P TV  E  + L
Sbjct: 715 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 772

Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717
             +V    +G S+LA L+   V  +VW
Sbjct: 773 LTQV---GLGASILALLVCLGVYWLVW 796


>gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo
           sapiens]
          Length = 997

 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%)

Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690
           C +W+         WS  GCQ    S     QCLC HLT F+    + P TV  E  + L
Sbjct: 646 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 703

Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717
             +V    +G S+LA L+   V  +VW
Sbjct: 704 LTQV---GLGASILALLVCLGVYWLVW 727


>gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo
           sapiens]
          Length = 873

 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%)

Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690
           C +W+         WS  GCQ    S     QCLC HLT F+    + P TV  E  + L
Sbjct: 516 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 573

Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717
             +V    +G S+LA L+   V  +VW
Sbjct: 574 LTQV---GLGASILALLVCLGVYWLVW 597


>gi|27436974 potassium voltage-gated channel, Shab-related subfamily,
            member 2 [Homo sapiens]
          Length = 911

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 46/209 (22%), Positives = 90/209 (43%), Gaps = 35/209 (16%)

Query: 1491 KWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSA 1550
            KW+FF G  N++D   IL  ++ + L   + S+ +    R      R +  +  +++   
Sbjct: 258  KWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVR------RVVQIFRIMRI--- 308

Query: 1551 ATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNL 1610
                         +++  L RHS  L+ +  TL R+++E+    L+IL L  G  I  +L
Sbjct: 309  -------------LRILKLARHSTGLQSLGFTLRRSYNELG---LLILFLAMGIMIFSSL 352

Query: 1611 LFGCSISDYRTFFSSA------VTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVL- 1663
            +F     +  T F+S        T+    +G         L  ++G    +  V+++ L 
Sbjct: 353  VFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALP 412

Query: 1664 --VVINLFVSAILMAFGKERKSLKKEAAL 1690
              +++N F S       ++ K++K+  AL
Sbjct: 413  IPIIVNNF-SEFYKEQKRQEKAIKRREAL 440


>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
          Length = 1287

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 19/59 (32%), Positives = 32/59 (54%)

Query: 802  SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFI 860
            +LG L ++++ HDNSG+   W V  V+V +      + F C  WL   + D  L+R+ +
Sbjct: 1004 NLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILV 1062


>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
          Length = 1274

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 20/59 (33%), Positives = 32/59 (54%)

Query: 802  SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFI 860
            +LG L ++++ HDNSG+   W V  V+V +      + F C  WL   + D  L+R+ I
Sbjct: 986  NLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILI 1044


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
            member 1 [Homo sapiens]
          Length = 858

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 35/210 (16%)

Query: 1490 QKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNS 1549
            +KW+FF G  N +D   IL  ++ + L   + S+ +    R      R +  +  +++  
Sbjct: 253  KKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVR------RVVQIFRIMRI-- 304

Query: 1550 AATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFN 1609
                          +++  L RHS  L+ +  TL R+++E+    L+IL L  G  I  +
Sbjct: 305  --------------LRILKLARHSTGLQSLGFTLRRSYNELG---LLILFLAMGIMIFSS 347

Query: 1610 LLFGCSISDYRTFFSSA------VTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVL 1663
            L+F     +  T F S        T+    +G         L  ++G    +  V+++ L
Sbjct: 348  LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIAL 407

Query: 1664 ---VVINLFVSAILMAFGKERKSLKKEAAL 1690
               +++N F S       ++ K++K+  AL
Sbjct: 408  PIPIIVNNF-SEFYKEQKRQEKAIKRREAL 436


>gi|224809323 G protein-coupled receptor 56 isoform b precursor
           [Homo sapiens]
          Length = 687

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%)

Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687
           QC +W + + T      WSSAGC+   + T  +T C CNHLT+FA    ++  +V V+  
Sbjct: 345 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 398

Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734
            K +L + +  VG  VS LA L+   +   + +R+K +    KV + +L
Sbjct: 399 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 444


>gi|224809320 G protein-coupled receptor 56 isoform c precursor
           [Homo sapiens]
          Length = 692

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%)

Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687
           QC +W + + T      WSSAGC+   + T  +T C CNHLT+FA    ++  +V V+  
Sbjct: 350 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 403

Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734
            K +L + +  VG  VS LA L+   +   + +R+K +    KV + +L
Sbjct: 404 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 449


>gi|224809318 G protein-coupled receptor 56 isoform b precursor
           [Homo sapiens]
          Length = 687

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%)

Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687
           QC +W + + T      WSSAGC+   + T  +T C CNHLT+FA    ++  +V V+  
Sbjct: 345 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 398

Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734
            K +L + +  VG  VS LA L+   +   + +R+K +    KV + +L
Sbjct: 399 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 444


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,671,425
Number of Sequences: 37866
Number of extensions: 2960370
Number of successful extensions: 7964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 7708
Number of HSP's gapped (non-prelim): 288
length of query: 1731
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1615
effective length of database: 13,855,062
effective search space: 22375925130
effective search space used: 22375925130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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