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Search of human proteins with 239745596
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
(1731 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 3497 0.0
gi|31559825 polycystin 1-like 3 [Homo sapiens] 3493 0.0
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 3491 0.0
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 3482 0.0
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 537 e-152
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 182 2e-45
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 179 2e-44
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 179 3e-44
gi|19923084 polycystin-1L1 [Homo sapiens] 122 4e-27
gi|4505835 polycystin 2 [Homo sapiens] 84 9e-16
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 81 8e-15
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 79 4e-14
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 79 4e-14
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 75 6e-13
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 67 2e-10
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 58 7e-08
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 58 7e-08
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 58 7e-08
gi|229093087 G protein-coupled receptor 97 [Homo sapiens] 47 2e-04
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 46 3e-04
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 45 5e-04
gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi... 45 5e-04
gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi... 45 5e-04
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 44 0.001
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 44 0.002
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 44 0.002
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 42 0.004
gi|224809323 G protein-coupled receptor 56 isoform b precursor [... 42 0.004
gi|224809320 G protein-coupled receptor 56 isoform c precursor [... 42 0.004
gi|224809318 G protein-coupled receptor 56 isoform b precursor [... 42 0.004
>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
Length = 1731
Score = 3497 bits (9069), Expect = 0.0
Identities = 1731/1731 (100%), Positives = 1731/1731 (100%)
Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ
Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
Query: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260
ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAPA
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260
Query: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320
INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ
Sbjct: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320
Query: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380
FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG
Sbjct: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380
Query: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440
QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR
Sbjct: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440
Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN
Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL
Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR
Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE
Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
Query: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
>gi|31559825 polycystin 1-like 3 [Homo sapiens]
Length = 1732
Score = 3493 bits (9057), Expect = 0.0
Identities = 1730/1732 (99%), Positives = 1730/1732 (99%), Gaps = 1/1732 (0%)
Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ
Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
Query: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENE-XTKRILALLAKCSSSVPGSRDKNNPVYVAP 1259
ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAP
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAP 1260
Query: 1260 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1319
AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH
Sbjct: 1261 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1320
Query: 1320 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1379
QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE
Sbjct: 1321 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1380
Query: 1380 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1439
GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM
Sbjct: 1381 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1440
Query: 1440 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1499
RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR
Sbjct: 1441 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1500
Query: 1500 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1559
NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV
Sbjct: 1501 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1560
Query: 1560 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1619
LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY
Sbjct: 1561 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1620
Query: 1620 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1679
RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK
Sbjct: 1621 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1680
Query: 1680 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1732
>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1731
Score = 3491 bits (9052), Expect = 0.0
Identities = 1727/1731 (99%), Positives = 1729/1731 (99%)
Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
GHLPTTCHYPLPAHLSKTLCHPISQFPSVL SITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240
Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
LEKSLIVSIDPDSPLLMTLYLGFQYQPNCT FHLNITLPKDKVWQKDEEYTW+LNPEHLQ
Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600
Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
Query: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
TR+QRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260
ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAPA
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260
Query: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320
INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ
Sbjct: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320
Query: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380
FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG
Sbjct: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380
Query: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440
QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR
Sbjct: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440
Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN
Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL
Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR
Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE
Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
Query: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1732
Score = 3482 bits (9030), Expect = 0.0
Identities = 1724/1732 (99%), Positives = 1727/1732 (99%), Gaps = 1/1732 (0%)
Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH
Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60
Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI
Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120
Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP
Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180
Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240
GHLPTTCHYPLPAHLSKTLCHPISQFPSVL SITSQVTSAASEPSSQPLPVITQLTMPVS
Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240
Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300
VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQ+ASGQVIDEIAGNFSRAVHGLQALNKL
Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQEASGQVIDEIAGNFSRAVHGLQALNKL 300
Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS
Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360
Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL
Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420
Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
LLSRQNIS+LPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN
Sbjct: 421 LLSRQNISSLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480
Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS
Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540
Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
LEKSLIVSIDPDSPLLMTLYLGFQYQPNCT FHLNITLPKDKVWQKDEEYTWVLNPEHLQ
Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600
Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR
Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660
Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK
Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720
Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC
Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780
Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF
Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840
Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF
Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900
Query: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
TR+QRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI
Sbjct: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960
Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL
Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020
Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL
Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080
Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE
Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140
Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200
GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALY LELSKDQATSWMISIILSVLQNIF
Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYRLELSKDQATSWMISIILSVLQNIF 1200
Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENE-XTKRILALLAKCSSSVPGSRDKNNPVYVAP 1259
ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAP
Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAP 1260
Query: 1260 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1319
AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH
Sbjct: 1261 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1320
Query: 1320 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1379
QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE
Sbjct: 1321 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1380
Query: 1380 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1439
GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM
Sbjct: 1381 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1440
Query: 1440 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1499
RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR
Sbjct: 1441 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1500
Query: 1500 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1559
NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV
Sbjct: 1501 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1560
Query: 1560 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1619
LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY
Sbjct: 1561 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1620
Query: 1620 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1679
RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK
Sbjct: 1621 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1680
Query: 1680 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731
ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP
Sbjct: 1681 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1732
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 537 bits (1383), Expect = e-152
Identities = 355/1139 (31%), Positives = 583/1139 (51%), Gaps = 67/1139 (5%)
Query: 248 LAETTSSPKEEGHPNTFTSY-LQVSLQKASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306
LA+ SS + H + + L + +++ +V + + G+ S GL+ + ++QE E
Sbjct: 898 LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954
Query: 307 LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366
L+++T + + AQ +L + SE LL + + + T F ++ +V +
Sbjct: 955 LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014
Query: 367 AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425
A + E + + L+ + L + P L + + ++ +R
Sbjct: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074
Query: 426 NISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485
+ SS P+A +L L V+++I +PF + ++ G
Sbjct: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134
Query: 486 SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544
++G + + S + +L+ V +L E+IEI+L R+ + PT LN+++ + + VNVTS E +
Sbjct: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193
Query: 545 LIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQHGIG 604
L + + + +TL LG+ Y PN + + L + DE TW+L+P+ L+ G G
Sbjct: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251
Query: 605 TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664
YY+T V E A V + T ++ C +W+ +TW +GCQVGP+++ +T CL
Sbjct: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311
Query: 665 CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724
CNHLTFF S F V+ +N+ T +LF +NPV V+ + L YV+ V+WAR+KD
Sbjct: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371
Query: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
D KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G EPHHL DP
Sbjct: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
VFERG +D FLL+T LG L SLRLWHDNSG PSWYVS+V+V D+ + RKW+FLCN
Sbjct: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
Query: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
WL++++GDC LD+VF ++++ F HLF F ++W SI +R + FTRVQ
Sbjct: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
Query: 905 RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964
R+SCC +LLLC M+ ++MFW + A++ + W E+++ + +++++FPINL+I
Sbjct: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
Query: 965 GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015
++F Q T P Q + D S +P+ ++ E K+ R +
Sbjct: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666
Query: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060
L W S DI L+ L+ ++ + GQ ++ ++
Sbjct: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726
Query: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106
AR P ++ + C YL L+ ++ L +G Q A
Sbjct: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784
Query: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166
QLQ L+ L + P P A S+ + KP GL W V WLL+ TS
Sbjct: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834
Query: 1167 ASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226
+AFFT LY L + + W+IS+ +S ++++F++QP+KV+ F ++L++ R+ ++
Sbjct: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD--DE 1892
Query: 1227 ENEXTKRILALLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTGDIL 1285
E+ LL ++ R+ + VY P + K LK++K F L +IL
Sbjct: 1893 EDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREIL 1952
Query: 1286 VQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYG 1344
+ FL +L+ Y ++ + ++L++ + +F+ FS + ++F+ WAN L+ +LYG
Sbjct: 1953 AYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYG 2011
Score = 203 bits (517), Expect = 1e-51
Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%)
Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
G FFT L+S + + + +++IY+L + YY +QG ++ ++ W +F K N
Sbjct: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221
Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
+L+ +IIL S+ L + +K L ++++ R R+ ++ ISF E ++A +++ F VL
Sbjct: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281
Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
L+TV+LW+LLR +P++ +I+ L RAW ++ GF+++IL +L Y+IA NL+FG + Y+
Sbjct: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341
Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
T F +A T+V L +GI + EEV PVLG+FLI + ++ M VV+NLF+S IL+AF +E
Sbjct: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401
Query: 1681 RK--SLKKEAALIDTLLQKLSNLLGI 1704
+K L +E ++D LL K+ + LGI
Sbjct: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427
Score = 38.9 bits (89), Expect = 0.044
Identities = 15/50 (30%), Positives = 28/50 (56%)
Query: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83
CY+ +F +AQ +C Q G L I ++ Q ++ ++ + ++WWIG
Sbjct: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 182 bits (462), Expect = 2e-45
Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%)
Query: 625 LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666
LV + QC W C +G +++ C+C
Sbjct: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153
Query: 667 -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725
H + + V+P V++ + + + NPV + + ++ YV WA +D+ D
Sbjct: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
Query: 726 MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
+ V VL DNDP YL+ ++TG R + T A V + L G+ S+ H L P
Sbjct: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
T RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++ + W F+C
Sbjct: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
Query: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
WL+V D LDR F E + + F + ++++W SI F R+Q
Sbjct: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
Query: 905 RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961
RLSCC+ +LL +++ N+MF+ +N T ++ + MR +++ I + +I P+
Sbjct: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441
Query: 962 LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992
L+I LF + PQ L P + +S+AS
Sbjct: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474
Score = 76.6 bits (187), Expect = 2e-13
Identities = 70/267 (26%), Positives = 115/267 (43%), Gaps = 24/267 (8%)
Query: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSK 1181
+EQ PS++ ++ KK L W V W L+ TS S+FF Y L
Sbjct: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604
Query: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK------ENEXTKRIL 1235
D++ W+ + S Q++ + QP K++ L S + P+ K + + T+ L
Sbjct: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660
Query: 1236 ALLAKCSSSVPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFK-----LTGDILVQILF 1290
+ + D+ + T+ R K+KK K IL +F
Sbjct: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720
Query: 1291 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1350
L LL+ I ++++ FY +Q I FS + + L+D Y W N +LLP L+ D
Sbjct: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779
Query: 1351 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1377
+ E S G+ L+ Q+ R K+ EK+
Sbjct: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805
Score = 68.6 bits (166), Expect = 5e-11
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%)
Query: 1435 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1492
F G TS+ L SF+ +K ++ ++ +I++L Y +GC + Q++
Sbjct: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991
Query: 1493 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1552
+ N+L+ ++ I +L+ L ++ L + Y + + FI F+ +V+
Sbjct: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051
Query: 1553 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1612
++GF + L ++ R +R+ R + A + ++ + Y L+F
Sbjct: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111
Query: 1613 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1672
G +Y S TV + + Q F+ + +LG + + +++M+ V+INLF +
Sbjct: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170
Query: 1673 ILMAFGKERKSLKKE 1687
IL A+ + ++ + +E
Sbjct: 2171 ILSAYEEMKQPVYEE 2185
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 179 bits (454), Expect = 2e-44
Identities = 206/850 (24%), Positives = 361/850 (42%), Gaps = 68/850 (8%)
Query: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590
L + +N T L+ + S +P+ L +YL + +PN + + + + + D Y
Sbjct: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
Query: 591 TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
T+ ++P + G+Y++ R Q VSV + C Y+ + W + G
Sbjct: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
Query: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
+++ + CL HLT F + FV P R V E T + N + + A
Sbjct: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
Query: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L
Sbjct: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
Query: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V
Sbjct: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
Query: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
IV D+ R FL N WL+V + +++ + S L FR L + + F
Sbjct: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
Query: 886 YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
++WLSI R P ++FTR+QR +CC+ L+ + N V + + + R ++
Sbjct: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
Query: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991
+ V + ++V+++P+ L I LF P Q+ L + + +S L +
Sbjct: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
Query: 992 -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050
+ L A V ++K + FL + + + S D+ ++ S + G
Sbjct: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
Query: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105
Q H G E ++ P + F ++Q+ L + + TQ H D L +
Sbjct: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
Query: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159
S + E L L PS + ++ + + GL K W S+
Sbjct: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
Query: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219
L + + + +W++S S L + +P+KV+ +SL+
Sbjct: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
Query: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278
RL+ + + T + S+ VP R + +++A E K K+L
Sbjct: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667
Query: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335
+ +LV +LFL + + A Y ++ + + + L AI + S F I ++ +PW
Sbjct: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727
Query: 1336 HILLPSLYGD 1345
H+LLP ++G+
Sbjct: 3728 HVLLPYVHGN 3737
Score = 38.1 bits (87), Expect = 0.075
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596
RF SF + +++SAA L + L V+ LR + V +TL RA E++G L
Sbjct: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
Query: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649
+++L YA +A L+ C S + + V G + E + L P+L
Sbjct: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 179 bits (453), Expect = 3e-44
Identities = 210/855 (24%), Positives = 363/855 (42%), Gaps = 77/855 (9%)
Query: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590
L + +N T L+ + S +P+ L +YL + +PN + + + + + D Y
Sbjct: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
Query: 591 TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
T+ ++P + G+Y++ R Q VSV + C Y+ + W + G
Sbjct: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
Query: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
+++ + CL HLT F + FV P R V E T + N + + A
Sbjct: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
Query: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L
Sbjct: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
Query: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V
Sbjct: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
Query: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
IV D+ R FL N WL+V + +++ + S L FR L + + F
Sbjct: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
Query: 886 YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
++WLSI R P ++FTR+QR +CC+ L+ + N V + + + R ++
Sbjct: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
Query: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDAS 992
+ V + ++V+++P+ L I LF P Q+ L + SCL +
Sbjct: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDI-----DSCLDSSV 3375
Query: 993 VEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDIT-KLVKLLS--SLVSSHL- 1048
++ T ++ ++ + +L W S + T LLS S+V S+L
Sbjct: 3376 LDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLR 3435
Query: 1049 ---EGQGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCD 1100
GQ H G E ++ P + F ++Q+ L + + TQ H D
Sbjct: 3436 QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETD 3495
Query: 1101 FLDAASQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLT 1154
L + S + E L L PS + ++ + + GL K W
Sbjct: 3496 LLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCA 3555
Query: 1155 SVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLY 1214
S+ L + + + +W++S S L + +P+KV+ +
Sbjct: 3556 SLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYF 3615
Query: 1215 SLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLK 1273
SL+ RL+ + + T + S+ VP R + +++A E K
Sbjct: 3616 SLVAK---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARK 3663
Query: 1274 KKKLFKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDF 1330
K+L + +LV +LFL + + A Y ++ + + + L AI + S F I ++
Sbjct: 3664 VKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEEL 3723
Query: 1331 YPWANHILLPSLYGD 1345
+PW H+LLP ++G+
Sbjct: 3724 WPWMAHVLLPYVHGN 3738
Score = 38.1 bits (87), Expect = 0.075
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596
RF SF + +++SAA L + L V+ LR + V +TL RA E++G L
Sbjct: 3973 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4032
Query: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649
+++L YA +A L+ C S + + V G + E + L P+L
Sbjct: 4033 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4086
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 122 bits (305), Expect = 4e-27
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%)
Query: 634 QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693
+C +W+ + W S P ++ + C + L FA + + V D KL
Sbjct: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747
Query: 694 VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753
N + ++ S++ Y V +R+ D + +K L + Y + + TG+
Sbjct: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806
Query: 754 RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813
R A T+KV I L G G SE L P+K +FER F+L+ LG L +RLWH
Sbjct: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866
Query: 814 DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873
D+ G SP W++S V+V ++ + W F CWL+ D ++R + FR L
Sbjct: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924
Query: 874 FSSMIVEKFTQDYLWLSIATRHPWNQFTRVQRLSCCMTLL 913
F E ++WLS+ +R +++ RL+ +LL
Sbjct: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964
Score = 61.2 bits (147), Expect = 8e-09
Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 28/235 (11%)
Query: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSV 1195
S EG P S L W +S W + G SLA + T + ++Q W+ + LSV
Sbjct: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175
Query: 1196 LQNIFISQPVKVVFFTFLYSLMMSRMPRLNKEN--EXTKRILALLAK---------CSSS 1244
+ IFI+QP+ V ++ E+ E T+ + + LA+ S S
Sbjct: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCS 2235
Query: 1245 VPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILFLT 1292
+P + V A A + HP +R ++ + DI + IL L
Sbjct: 2236 IPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLL 2295
Query: 1293 LLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1343
LL+ IY + + + L+QAI K F+ ++ + D++ W+ LL LY
Sbjct: 2296 LLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 84.3 bits (207), Expect = 9e-16
Identities = 47/221 (21%), Positives = 107/221 (48%), Gaps = 1/221 (0%)
Query: 1469 QVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNM 1528
++I+ + YY + +++ K +F N LD I+++S + +G+++ S + + +
Sbjct: 477 EIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTS-NVEVL 535
Query: 1529 ARYRDDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWD 1588
++ +DQ+ F +F ++ V ++L+ + + + +S T+SR
Sbjct: 536 LQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAK 595
Query: 1589 EVVGFLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPV 1648
++ GF ++ I+ YA L+FG + D+ TF T +++G + E+ + V
Sbjct: 596 DLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRV 655
Query: 1649 LGTFLILTSVILMVLVVINLFVSAILMAFGKERKSLKKEAA 1689
LG T V M +++N+F++ I + + + L ++ A
Sbjct: 656 LGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKA 696
Score = 33.1 bits (74), Expect = 2.4
Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 1271 TLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFY---------LHQAIWKTFSHQF 1321
T ++K L + +++ +LFL +L Y +SN +Y L + KT F
Sbjct: 211 TNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNF 270
Query: 1322 SEIKLLQDFYPWANHILLPSLYGDYRGKN 1350
+ ++DF+ + LL LY + N
Sbjct: 271 KTLSSMEDFWKFTEGSLLDGLYWKMQPSN 299
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
sapiens]
Length = 2211
Score = 81.3 bits (199), Expect = 8e-15
Identities = 46/111 (41%), Positives = 66/111 (59%), Gaps = 6/111 (5%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y + TG R A T A V ITL+G G S L K+ FE+G +DVF + T ++G
Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NNVG 103
Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKR---KWHFLCNCWLAVDLGD 852
++ +R+ HDN+G++ SWY+ VIV DM KR +++F CN WL+ GD
Sbjct: 104 LIYKVRIEHDNTGLNASWYLDHVIVTDM--KRPHLRYYFNCNNWLSKVEGD 152
Score = 79.0 bits (193), Expect = 4e-14
Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803
Y + V T A T A V I ++G G S L FER D F SL
Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884
Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863
G+L LR+WHDN G+ P W++S V V D + +HF C+CWL+ GD + R F +
Sbjct: 1885 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 1944
Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894
+ +++E T++ +WL + R
Sbjct: 1945 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 1979
Score = 75.1 bits (183), Expect = 6e-13
Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y ++VYTG A T A V I ++G G + L + +K FE+G D F+L LG
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRL-ENEKDNFEKGAEDRFILDA-PDLG 231
Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
L + + H+N G S W++SQ+++ D+ KRK+ F N WLA+D D ++ R
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDEDDGKIQR 284
Score = 73.2 bits (178), Expect = 2e-12
Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802
Y +Q++TG A T AKV IT+YG G + +L + + FERG D F++
Sbjct: 1462 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 1520
Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859
LG ++ ++L HDNS WYV +V + + + ++ FLC WL++ D L+R+F
Sbjct: 1521 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLERLF 1577
Score = 70.9 bits (172), Expect = 1e-11
Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 3/122 (2%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSE-GRSEPHHLCDPQKT-VFERGGLDVFLLTTWTS 802
Y +QV TG A T A V +T+YG E G + L K+ FE+G D F +
Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-ID 1082
Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPV 862
LG L +R+ HDN+G W++ ++ + DM + ++F C WLAV+ D +L R +PV
Sbjct: 1083 LGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEEDDGQLSRELLPV 1142
Query: 863 SK 864
+
Sbjct: 1143 DE 1144
Score = 69.3 bits (168), Expect = 3e-11
Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y + V TGY A T A V +T++G+ G + L + +FERG D F L T LG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 2152
Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGD 852
L +RL HD+SG W V +V V + + F C WL GD
Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 2200
Score = 63.2 bits (152), Expect = 2e-09
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 5/156 (3%)
Query: 721 KDQADMQKVKVTVLADNDPSAQ-FHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL 779
KD+ D Q V+ + +D+ + + F Y I + TG A+T ++V I LYG + + L
Sbjct: 661 KDKDDGQLVRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVL 720
Query: 780 C---DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKR 836
+ K FERG +D F L T ++GN++ L + HD++G+ SW++ V + +
Sbjct: 721 LVSDNNLKDYFERGRVDEFTLET-LNIGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGK 779
Query: 837 KWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRH 872
++ F N WL + D L+ P E+ H
Sbjct: 780 QYTFPANRWLDKNQADGRLEVELYPSEVVEIQKLVH 815
Score = 62.0 bits (149), Expect = 5e-09
Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Query: 734 LADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT---VFERG 790
L D S F I+ TG +++A T A V ITL+G++ + L KT FER
Sbjct: 1168 LEQKDKSTTFSVTIK--TGVKKNAGTDANVFITLFGTQDDTGMT-LLKSSKTNSDKFERD 1224
Query: 791 GLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDL 850
+++F + T LG+L +RL HDN+G +P W+V V V ++ + F C WLA +
Sbjct: 1225 SIEIFTVET-LDLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNE 1283
Query: 851 GDCELDR 857
D + R
Sbjct: 1284 DDGSIIR 1290
Score = 61.6 bits (148), Expect = 6e-09
Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 2/92 (2%)
Query: 744 HYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSL 803
HY ++++TG A T+A+V + +YG +G++E L K VFER D F L +
Sbjct: 815 HYEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSK-VFERASKDTFQLEA-ADV 872
Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVK 835
G ++ LRL H G PSW+V V + + V+
Sbjct: 873 GEVYKLRLGHTGEGFGPSWFVDTVWLRHLVVR 904
Score = 61.2 bits (147), Expect = 8e-09
Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 742 QFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWT 801
+F + + V+T + A T + + I +YG +GR++ L +P F+ G ++ F +
Sbjct: 424 KFPWSLWVWTTDLKKAGTNSPIFIQIYGQKGRTD-EILLNPNNKWFKPGIIEKFRIEL-P 481
Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
LG + +R+WHD W++ ++ + + K K++F CN WL + D E+ R
Sbjct: 482 DLGRFYKIRVWHDKRSSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDDNEIVR 537
Score = 58.2 bits (139), Expect = 7e-08
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
D K++ +L + Y++ V+TG R A T +K+ + +YG+ G + +
Sbjct: 278 DDGKIQRDILVGGAETTAITYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIF-LEG 336
Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
VF+RG D+F + L L + + H N GV+ W+ +V++ + F C+
Sbjct: 337 GVFDRGRTDIFHIELAVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSN 396
Query: 845 WLAVDLGDCELDR 857
WL D ++R
Sbjct: 397 WLDEKKADGLIER 409
Score = 55.8 bits (133), Expect = 3e-07
Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802
Y + V TG A T A V + L+G G + L C +FE+G D F + + T
Sbjct: 555 YHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIESVT- 613
Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCD--MAVKRKWHFLCNCWLAVDLGDCELDRVFI 860
+ N+ +R+ HD G WY+ +V+V + F C WL D D +L R +
Sbjct: 614 MRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKDDGQLVRELL 673
Query: 861 PV-SKRELFSFRHLFS 875
P S L +FR+ S
Sbjct: 674 PSDSSATLKNFRYHIS 689
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGR-SEPHHLCD---PQKTVFERGGLDVFLLTTW 800
Y I +YT +A T A + I +YG + ++ +LC QK FER F++
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 1367
Query: 801 TSLGNLHSLRLWHDNSGVSPSWYVSQV----IVCDMAVKRKWHFLCNCWLAVDLGDCELD 856
+ +R+ H+N+G++P W+ S V ++ D F C+ WLA D +
Sbjct: 1368 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 1427
Query: 857 RVFIP 861
R +P
Sbjct: 1428 RELVP 1432
Score = 43.9 bits (102), Expect = 0.001
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y + V+TG T + + +TLYG G +E L D +K FER D F++ +
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIA 1755
Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847
+R+ D G P W++ ++++ +M F WL+
Sbjct: 1756 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
sapiens]
Length = 1114
Score = 79.0 bits (193), Expect = 4e-14
Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803
Y + V T A T A V I ++G G S L FER D F SL
Sbjct: 776 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835
Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863
G+L LR+WHDN G+ P W++S V V D + +HF C+CWL+ GD + R F +
Sbjct: 836 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 895
Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894
+ +++E T++ +WL + R
Sbjct: 896 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 930
Score = 73.2 bits (178), Expect = 2e-12
Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802
Y +Q++TG A T AKV IT+YG G + +L + + FERG D F++
Sbjct: 351 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 409
Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859
LG ++ ++L HDNS WYV +V + + + ++ FLC WL++ D L+R+F
Sbjct: 410 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLERLF 466
Score = 62.0 bits (149), Expect = 5e-09
Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Query: 734 LADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT---VFERG 790
L D S F I+ TG +++A T A V ITL+G++ + L KT FER
Sbjct: 57 LEQKDKSTTFSVTIK--TGVKKNAGTDANVFITLFGTQDDTGMT-LLKSSKTNSDKFERD 113
Query: 791 GLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDL 850
+++F + T LG+L +RL HDN+G +P W+V V V ++ + F C WLA +
Sbjct: 114 SIEIFTVET-LDLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNE 172
Query: 851 GDCELDR 857
D + R
Sbjct: 173 DDGSIIR 179
Score = 57.4 bits (137), Expect = 1e-07
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 3/117 (2%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEG-RSEPHHLCDPQ-KTVFERGGLDVFLLTTWTS 802
Y + V TG + AAT ++ I L G + RS+ L P+ K F RG ++ F +
Sbjct: 518 YYVSVTTGKHKDAATDSRAFIFLIGEDDERSKRIWLDYPRGKRGFSRGSVEEFYVAG-LD 576
Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859
+G + + L HD + W V ++ + K+ CNCWLA D GD RVF
Sbjct: 577 VGIIKKIELGHDGASPESCWLVEELCLAVPTQGTKYMLNCNCWLAKDRGDGITSRVF 633
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGR-SEPHHLCD---PQKTVFERGGLDVFLLTTW 800
Y I +YT +A T A + I +YG + ++ +LC QK FER F++
Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 256
Query: 801 TSLGNLHSLRLWHDNSGVSPSWYVSQV----IVCDMAVKRKWHFLCNCWLAVDLGDCELD 856
+ +R+ H+N+G++P W+ S V ++ D F C+ WLA D +
Sbjct: 257 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 316
Query: 857 RVFIP 861
R +P
Sbjct: 317 RELVP 321
Score = 43.9 bits (102), Expect = 0.001
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y + V+TG T + + +TLYG G +E L D +K FER D F++ +
Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIA 706
Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847
+R+ D G P W++ ++++ +M F WL+
Sbjct: 707 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTT 799
Y + V TGY A T A V +T++G+ G + L + +FERG D F L T
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET 1099
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo
sapiens]
Length = 512
Score = 79.0 bits (193), Expect = 4e-14
Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803
Y + V T A T A V I ++G G S L FER D F SL
Sbjct: 126 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185
Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863
G+L LR+WHDN G+ P W++S V V D + +HF C+CWL+ GD + R F +
Sbjct: 186 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 245
Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894
+ +++E T++ +WL + R
Sbjct: 246 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 280
Score = 69.3 bits (168), Expect = 3e-11
Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y + V TGY A T A V +T++G+ G + L + +FERG D F L T LG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 453
Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGD 852
L +RL HD+SG W V +V V + + F C WL GD
Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 501
Score = 42.4 bits (98), Expect = 0.004
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 749 VYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHS 808
V+TG T + + +TLYG G +E L D +K FER D F++ +
Sbjct: 3 VWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIAPFTK 60
Query: 809 LRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847
+R+ D G P W++ ++++ +M F WL+
Sbjct: 61 MRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 75.1 bits (183), Expect = 6e-13
Identities = 54/242 (22%), Positives = 112/242 (46%), Gaps = 13/242 (5%)
Query: 1469 QVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNM 1528
+VI+ + + YY + +L + R+ + NILD +IL+S + +G + + M
Sbjct: 356 EVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLM 415
Query: 1529 ARYRDDQD-----RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTL 1583
+ + F++F++ N A +L A ++++ + + + +S TL
Sbjct: 416 GKLLQQPNTYADFEFLAFWQTQYNNMNAVNL-----FFAWIKIFKYISFNKTMTQLSSTL 470
Query: 1584 SRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVF 1643
+R +++GF ++ I+ YA LLFG + ++ TF T +++G +
Sbjct: 471 ARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAID 530
Query: 1644 ALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKERKSL---KKEAALIDTLLQKLSN 1700
+ +LG +T V + V++N+F++ I + + ++ L K E L D L Q +
Sbjct: 531 NANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNK 590
Query: 1701 LL 1702
L
Sbjct: 591 TL 592
Score = 34.7 bits (78), Expect = 0.83
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
Query: 1269 ERTLKKKKLFKLTG--DILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH------- 1319
E T + ++L+ T ++LV I+FL + Y +S+ +Y + + + F H
Sbjct: 87 ENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGV 146
Query: 1320 QFSEIKLLQDFYPWANHILLPSLY 1343
F I + DF+ +A LL SLY
Sbjct: 147 SFQAISSMADFWDFAQGPLLDSLY 170
>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
Length = 613
Score = 67.0 bits (162), Expect = 2e-10
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 4/201 (1%)
Query: 1477 CYYAFIQGCQ----LKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYR 1532
C + F+ Q +K+ K +F N L+ ++L+ F+ + + + +
Sbjct: 290 CIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLL 349
Query: 1533 DDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVG 1592
+++ FY + +++ + A ++++ + + + +S TLSR ++VG
Sbjct: 350 KSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVG 409
Query: 1593 FLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTF 1652
F ++ I+ YA L+FG + D+ TF +S +++G + + +P+LG
Sbjct: 410 FAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPI 469
Query: 1653 LILTSVILMVLVVINLFVSAI 1673
+T + + V++N+F++ I
Sbjct: 470 YFITFIFFVFFVLLNMFLAII 490
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%)
Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767
FYV W AR ++ ++ + + +L+ P Y + V TG +A T A V I++
Sbjct: 7 FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65
Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826
+G +G + L + + F RG D F L LG+L + + HD G W++
Sbjct: 66 HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124
Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
V++ D ++ F C+ WL DC++ R
Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%)
Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774
VW + QAD V ++ V+ Y + VYTG + A T ++V + L+G G S
Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665
Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833
L V F+RG +D F + SLG L + L + S S WY QVIV +
Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724
Query: 834 VKRKWHFLC 842
+ F C
Sbjct: 725 TTSESIFTC 733
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%)
Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767
FYV W AR ++ ++ + + +L+ P Y + V TG +A T A V I++
Sbjct: 7 FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65
Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826
+G +G + L + + F RG D F L LG+L + + HD G W++
Sbjct: 66 HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124
Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
V++ D ++ F C+ WL DC++ R
Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%)
Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774
VW + QAD V ++ V+ Y + VYTG + A T ++V + L+G G S
Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665
Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833
L V F+RG +D F + SLG L + L + S S WY QVIV +
Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724
Query: 834 VKRKWHFLC 842
+ F C
Sbjct: 725 TTSESIFTC 733
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%)
Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767
FYV W AR ++ ++ + + +L+ P Y + V TG +A T A V I++
Sbjct: 7 FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65
Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826
+G +G + L + + F RG D F L LG+L + + HD G W++
Sbjct: 66 HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124
Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857
V++ D ++ F C+ WL DC++ R
Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%)
Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774
VW + QAD V ++ V+ Y + VYTG + A T ++V + L+G G S
Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665
Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833
L V F+RG +D F + SLG L + L + S S WY QVIV +
Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724
Query: 834 VKRKWHFLC 842
+ F C
Sbjct: 725 TTSESIFTC 733
>gi|229093087 G protein-coupled receptor 97 [Homo sapiens]
Length = 549
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 15/90 (16%)
Query: 635 CYYWEIHNQT---WSSAGC--QVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIK 689
C +W++ T WSS GC +V P+ T+ C C+HLTFFA ++ R + T+
Sbjct: 215 CVFWDVTKGTTGDWSSEGCSTEVRPEGTV----CCCDHLTFFA----LLLRPTLDQSTVH 266
Query: 690 LFLRVTNNPVGVSLLASLLGFYVITVVWAR 719
+ R++ GVS++ L F +I + R
Sbjct: 267 ILTRISQAGCGVSMI--FLAFTIILYAFLR 294
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 46.2 bits (108), Expect = 3e-04
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Y + V TG + A T + ++L GS G SE H L P FERG +D + +T LG
Sbjct: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Query: 805 NLHSLRLWHDNSGVSPSWYVSQV 827
+ +R+ ++ WY+ +
Sbjct: 64 EIQLVRIEKRKYWLNDDWYLKYI 86
>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo
sapiens]
Length = 1079
Score = 45.4 bits (106), Expect = 5e-04
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690
C +W+ WS GCQ S QCLC HLT F+ + P TV E + L
Sbjct: 715 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 772
Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717
+V +G S+LA L+ V +VW
Sbjct: 773 LTQV---GLGASILALLVCLGVYWLVW 796
>gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo
sapiens]
Length = 997
Score = 45.4 bits (106), Expect = 5e-04
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690
C +W+ WS GCQ S QCLC HLT F+ + P TV E + L
Sbjct: 646 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 703
Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717
+V +G S+LA L+ V +VW
Sbjct: 704 LTQV---GLGASILALLVCLGVYWLVW 727
>gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo
sapiens]
Length = 873
Score = 45.4 bits (106), Expect = 5e-04
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690
C +W+ WS GCQ S QCLC HLT F+ + P TV E + L
Sbjct: 516 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 573
Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717
+V +G S+LA L+ V +VW
Sbjct: 574 LTQV---GLGASILALLVCLGVYWLVW 597
>gi|27436974 potassium voltage-gated channel, Shab-related subfamily,
member 2 [Homo sapiens]
Length = 911
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/209 (22%), Positives = 90/209 (43%), Gaps = 35/209 (16%)
Query: 1491 KWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSA 1550
KW+FF G N++D IL ++ + L + S+ + R R + + +++
Sbjct: 258 KWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVR------RVVQIFRIMRI--- 308
Query: 1551 ATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNL 1610
+++ L RHS L+ + TL R+++E+ L+IL L G I +L
Sbjct: 309 -------------LRILKLARHSTGLQSLGFTLRRSYNELG---LLILFLAMGIMIFSSL 352
Query: 1611 LFGCSISDYRTFFSSA------VTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVL- 1663
+F + T F+S T+ +G L ++G + V+++ L
Sbjct: 353 VFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALP 412
Query: 1664 --VVINLFVSAILMAFGKERKSLKKEAAL 1690
+++N F S ++ K++K+ AL
Sbjct: 413 IPIIVNNF-SEFYKEQKRQEKAIKRREAL 440
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 43.5 bits (101), Expect = 0.002
Identities = 19/59 (32%), Positives = 32/59 (54%)
Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFI 860
+LG L ++++ HDNSG+ W V V+V + + F C WL + D L+R+ +
Sbjct: 1004 NLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILV 1062
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 43.5 bits (101), Expect = 0.002
Identities = 20/59 (33%), Positives = 32/59 (54%)
Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFI 860
+LG L ++++ HDNSG+ W V V+V + + F C WL + D L+R+ I
Sbjct: 986 NLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILI 1044
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 42.4 bits (98), Expect = 0.004
Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 35/210 (16%)
Query: 1490 QKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNS 1549
+KW+FF G N +D IL ++ + L + S+ + R R + + +++
Sbjct: 253 KKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVR------RVVQIFRIMRI-- 304
Query: 1550 AATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFN 1609
+++ L RHS L+ + TL R+++E+ L+IL L G I +
Sbjct: 305 --------------LRILKLARHSTGLQSLGFTLRRSYNELG---LLILFLAMGIMIFSS 347
Query: 1610 LLFGCSISDYRTFFSSA------VTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVL 1663
L+F + T F S T+ +G L ++G + V+++ L
Sbjct: 348 LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIAL 407
Query: 1664 ---VVINLFVSAILMAFGKERKSLKKEAAL 1690
+++N F S ++ K++K+ AL
Sbjct: 408 PIPIIVNNF-SEFYKEQKRQEKAIKRREAL 436
>gi|224809323 G protein-coupled receptor 56 isoform b precursor
[Homo sapiens]
Length = 687
Score = 42.4 bits (98), Expect = 0.004
Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%)
Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687
QC +W + + T WSSAGC+ + T +T C CNHLT+FA ++ +V V+
Sbjct: 345 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 398
Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734
K +L + + VG VS LA L+ + + +R+K + KV + +L
Sbjct: 399 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 444
>gi|224809320 G protein-coupled receptor 56 isoform c precursor
[Homo sapiens]
Length = 692
Score = 42.4 bits (98), Expect = 0.004
Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%)
Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687
QC +W + + T WSSAGC+ + T +T C CNHLT+FA ++ +V V+
Sbjct: 350 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 403
Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734
K +L + + VG VS LA L+ + + +R+K + KV + +L
Sbjct: 404 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 449
>gi|224809318 G protein-coupled receptor 56 isoform b precursor
[Homo sapiens]
Length = 687
Score = 42.4 bits (98), Expect = 0.004
Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%)
Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687
QC +W + + T WSSAGC+ + T +T C CNHLT+FA ++ +V V+
Sbjct: 345 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 398
Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734
K +L + + VG VS LA L+ + + +R+K + KV + +L
Sbjct: 399 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 444
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,671,425
Number of Sequences: 37866
Number of extensions: 2960370
Number of successful extensions: 7964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 7708
Number of HSP's gapped (non-prelim): 288
length of query: 1731
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1615
effective length of database: 13,855,062
effective search space: 22375925130
effective search space used: 22375925130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.