Guide to the Human Genome
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Search of human proteins with 239744574

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744574 PREDICTED: hypothetical protein [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169204626 PREDICTED: hypothetical protein [Homo sapiens]           988   0.0  
gi|239750266 PREDICTED: hypothetical protein [Homo sapiens]           988   0.0  
gi|239744574 PREDICTED: hypothetical protein [Homo sapiens]           988   0.0  
gi|117320513 coiled-coil domain containing 155 [Homo sapiens]         124   3e-28
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    49   8e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    44   3e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    44   3e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        44   3e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        44   3e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         44   3e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         44   3e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         44   3e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         44   3e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         44   3e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         44   3e-04
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       44   4e-04
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               43   8e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    42   0.001
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    42   0.001
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    42   0.001
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       42   0.001
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       42   0.001
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    42   0.002
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    41   0.002
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    41   0.003
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                41   0.003
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    41   0.003
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    41   0.003
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    41   0.003
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    41   0.003

>gi|169204626 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 501

 Score =  988 bits (2555), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV 60
           MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV
Sbjct: 1   MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV 60

Query: 61  LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV 120
           LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV
Sbjct: 61  LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV 120

Query: 121 SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD 180
           SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD
Sbjct: 121 SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD 180

Query: 181 SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS 240
           SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS
Sbjct: 181 SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS 240

Query: 241 VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE 300
           VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE
Sbjct: 241 VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE 300

Query: 301 GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY 360
           GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY
Sbjct: 301 GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY 360

Query: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL 420
           VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL
Sbjct: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL 420

Query: 421 EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
           EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG
Sbjct: 421 EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480

Query: 481 RLKALHHEIALQLLTYIRKRI 501
           RLKALHHEIALQLLTYIRKRI
Sbjct: 481 RLKALHHEIALQLLTYIRKRI 501


>gi|239750266 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 501

 Score =  988 bits (2555), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV 60
           MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV
Sbjct: 1   MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV 60

Query: 61  LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV 120
           LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV
Sbjct: 61  LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV 120

Query: 121 SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD 180
           SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD
Sbjct: 121 SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD 180

Query: 181 SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS 240
           SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS
Sbjct: 181 SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS 240

Query: 241 VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE 300
           VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE
Sbjct: 241 VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE 300

Query: 301 GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY 360
           GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY
Sbjct: 301 GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY 360

Query: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL 420
           VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL
Sbjct: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL 420

Query: 421 EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
           EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG
Sbjct: 421 EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480

Query: 481 RLKALHHEIALQLLTYIRKRI 501
           RLKALHHEIALQLLTYIRKRI
Sbjct: 481 RLKALHHEIALQLLTYIRKRI 501


>gi|239744574 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 501

 Score =  988 bits (2555), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV 60
           MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV
Sbjct: 1   MASPRKVTEKRHNPVESICRKIRAIHKREAISNPIQQIIKYQSSSFDSPQTNTKKYFEEV 60

Query: 61  LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV 120
           LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV
Sbjct: 61  LRKMTAACVPTPGSHWSSSEEVDAFISSPQIISPRTPSTSHLSSPETATYSVILTSSENV 120

Query: 121 SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD 180
           SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD
Sbjct: 121 SKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQSLKCFDPQD 180

Query: 181 SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS 240
           SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS
Sbjct: 181 SVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIFNACDIKRKELICSSFSKGS 240

Query: 241 VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE 300
           VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE
Sbjct: 241 VGVAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWE 300

Query: 301 GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY 360
           GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY
Sbjct: 301 GVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAY 360

Query: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL 420
           VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL
Sbjct: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL 420

Query: 421 EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
           EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG
Sbjct: 421 EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480

Query: 481 RLKALHHEIALQLLTYIRKRI 501
           RLKALHHEIALQLLTYIRKRI
Sbjct: 481 RLKALHHEIALQLLTYIRKRI 501


>gi|117320513 coiled-coil domain containing 155 [Homo sapiens]
          Length = 562

 Score =  124 bits (310), Expect = 3e-28
 Identities = 81/252 (32%), Positives = 133/252 (52%), Gaps = 21/252 (8%)

Query: 213 KEEALTSIFNACDIKRKELICSSFSKGSVGVAKIINFLRQTTSQNSEDSGLEQLWNMLDP 272
           +E+ L S F ACD +R          G+V VA+++ +L   T Q  +D+ L+ L N LDP
Sbjct: 33  EEQILNSTFEACDPQRT---------GTVAVAQVLAYLEAVTGQGPQDARLQTLANSLDP 83

Query: 273 EKRDPH--VDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKSDGTMKMST 330
               P   VDL+TF  +M+DW+A C     G+       +++    Q  + S        
Sbjct: 84  NGEGPKATVDLDTFLVVMRDWIAAC-QLHGGLE------LEEETAFQGALTSRQLPSGCP 136

Query: 331 DITDSTLGSFEALGGETSKGVLE-VSDLIAYVADLHFNKRKLEEENNKFKLALETLEETN 389
           +  +    + E+ GGE  +  L+  +DL++ + DL  + R+L  EN K + ++ET EE +
Sbjct: 137 EAEEP--ANLESFGGEDPRPELQATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGS 194

Query: 390 SQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENR 449
           ++L E+   LR Q+ S  QA+     + EELE+LK    + EEQ   ++AQ++Q E E +
Sbjct: 195 ARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQ 254

Query: 450 ALILKIRILQEE 461
            L+ ++  LQEE
Sbjct: 255 HLVAEMETLQEE 266



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 10/106 (9%)

Query: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL---EELKL 425
           R+ E+E       +ETL+E N +L  +   ++   K + +  M  + LK +L   E L  
Sbjct: 247 RQAEKEQQHLVAEMETLQEENGKLLAERDGVK---KRSQELAMEKDTLKRQLFECEHLIC 303

Query: 426 SMNASEEQKSMIVAQSKQLETENRA----LILKIRILQEEMSDTYQ 467
             +    +++  V    Q   E R     L L+I  L+E++S TY+
Sbjct: 304 QRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE 349


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 87/395 (22%), Positives = 158/395 (40%), Gaps = 44/395 (11%)

Query: 106  ETATYSVILTSSENVSKPKSQSNK----NYTSLMSQIRKAEFFSNKDLNNYCSENNFSTL 161
            ETAT S+    + NVS+ K    K         +SQI   +  + +DL+N   E+N    
Sbjct: 929  ETATRSI----TNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNT 984

Query: 162  TLDFDSTFVQSLKCFDPQDSVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIF 221
             LD               D +V K        +   ++     I +I   CKE    S  
Sbjct: 985  QLDLLGN-----------DYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSK 1033

Query: 222  NACDIKRKELICSSFSKGSVGVAKIINFLRQTTSQNSED--SGLEQLWNMLDPEKRDPHV 279
             +  I+  E           G     N L++   +N +D     E L   L  E ++ +V
Sbjct: 1034 KSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNV 1093

Query: 280  DLETFQAMMKDWMAYCGNTWEGVNHRLSSIID-DSVCEQDGIKSDGTMKMSTDITDSTLG 338
             L+     + +         +GV    + I + +++ E   ++   + K+  DI +    
Sbjct: 1094 TLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEK--- 1150

Query: 339  SFEALGGETSKGVLE----VSDLIAYVADLHFNKRKLEEE-----NN----KFKLAL-ET 384
              E++  +  + + E    + D +    DL+  + KL+EE     NN    K  L L E 
Sbjct: 1151 --ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEE 1208

Query: 385  LEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELE--ELKLSMNASEEQKSMIVAQSK 442
             EETN Q +E   E  L   SA    ++ +L ++E +  +LK  +  +++Q   +  +  
Sbjct: 1209 EEETNRQETEKLKE-ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 1267

Query: 443  QLETENRALILKIRILQEEMSDTYQRIVPNQFRIE 477
             +  E++ L +KI  L+++ +   Q +   Q  I+
Sbjct: 1268 VMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQ 1302



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 33/137 (24%), Positives = 63/137 (45%), Gaps = 22/137 (16%)

Query: 346 ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKS 405
           E  K   EV   IA + D+    R L+E N   +  L T+E       E+  EL  Q+  
Sbjct: 819 EDQKKSEEVRPNIAEIEDI----RVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVH 874

Query: 406 AHQAIM---RTNL-LKEELE-----------ELKLSMNASEEQKSMIVAQSKQLETENRA 450
             Q +    + NL L +E++           EL +  + ++EQ+  I+  S ++ET  R+
Sbjct: 875 FQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRS 934

Query: 451 L---ILKIRILQEEMSD 464
           +   + +I+++  ++ +
Sbjct: 935 ITNNVSQIKLMHTKIDE 951


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 34/114 (29%), Positives = 60/114 (52%), Gaps = 6/114 (5%)

Query: 362 ADLHFNKRKLEEENNKFK---LALETLEETNSQLSEDCTELRLQVKSAHQAIMR---TNL 415
           ++L    RKL++  + FK     LE+LE+ NSQL E+  ELR  V+S   A M+     L
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQL 725

Query: 416 LKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRI 469
             +ELE  K  +    E       ++++LE   + L ++ + LQ+ + ++ ++I
Sbjct: 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 33/136 (24%), Positives = 63/136 (46%), Gaps = 8/136 (5%)

Query: 364 LHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEEL 423
           L  + + L+ EN + +  LE   +   QL  +  +L ++ ++  + +    +  + LE+L
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813

Query: 424 KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRI-EIEGRL 482
           +    + E++ S +    KQLE EN+ L       Q E+ DT   +  N  +I  +E   
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRL-----RQQAEIKDT--TLEENNVKIGNLEKEN 866

Query: 483 KALHHEIALQLLTYIR 498
           K L  EI +   + +R
Sbjct: 867 KTLSKEIGIYKESCVR 882



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 31/176 (17%)

Query: 331 DITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLE---- 386
           ++T S L   E      +K V E+   +  V        K+E+EN +    +E LE    
Sbjct: 456 ELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIV 515

Query: 387 ------ETNSQLSEDCTELRLQVKSAHQAIMRTN-----LLKEELEELKLSMNASEEQKS 435
                 +    LS+D  + + Q++   + +   +     +L++E E L  ++ +S  Q+S
Sbjct: 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTV-SSLRQRS 574

Query: 436 MIVAQS--KQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEGR--LKALHH 487
            I A++  K +E EN       +IL E + +T  ++     +IE E R   K L H
Sbjct: 575 QISAEARVKDIEKEN-------KILHESIKETSSKL----SKIEFEKRQIKKELEH 619



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 6/125 (4%)

Query: 370 KLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM-- 427
           KLE EN      +E L  T   +  + +++    K   +   +  +L+ E+ + K S+  
Sbjct: 464 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN 523

Query: 428 --NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRI--VPNQFRIEIEGRLK 483
             N S++         K +ET       +I+IL++E     Q +  +  + +I  E R+K
Sbjct: 524 CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVK 583

Query: 484 ALHHE 488
            +  E
Sbjct: 584 DIEKE 588



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 38/202 (18%), Positives = 87/202 (43%), Gaps = 30/202 (14%)

Query: 279  VDLETFQAMMKDWMA------YCGNTWEGVNHRLSSI-------------IDDSVCEQDG 319
            +D++T   + +D ++         N  E + H L  I              DDS  +   
Sbjct: 899  IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE 958

Query: 320  IKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFK 379
             K + T+K S +I +  + + EA   E++    ++   +  V   +   ++ ++E     
Sbjct: 959  SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE----- 1013

Query: 380  LALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVA 439
               E + +++  +S +  +   + +   + +++   +K+ L E++ +    + +K  +  
Sbjct: 1014 ---ERMVQSSPPISGEDNKWERESQETTRELLK---VKDRLIEVERNNATLQAEKQALKT 1067

Query: 440  QSKQLETENRALILKIRILQEE 461
            Q KQLET+N  L  +I  LQ +
Sbjct: 1068 QLKQLETQNNNLQAQILALQRQ 1089



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 12/102 (11%)

Query: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSE--------DCTELRLQVKSAHQAIMR 412
           +A L    ++LE E  + K  LE L+ +  +           D    RLQ K+   +  +
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ-KTLENSNKK 778

Query: 413 TNLLKEELEELKLSMNASEEQKSMIVAQSK---QLETENRAL 451
              L+ EL++L++     ++    +   SK   QLE EN++L
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 11/99 (11%)

Query: 353 EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMR 412
           EVS     + D+ F K ++EE           L+E N  L E  T L  Q++       +
Sbjct: 328 EVSRYKERLHDIEFYKARVEE-----------LKEDNQVLLETKTMLEDQLEGTRARSDK 376

Query: 413 TNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL 451
            + L++E  +LK  ++  E ++ M   + ++L  EN  L
Sbjct: 377 LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL 415



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 11/110 (10%)

Query: 382 LETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEE---LEELKLSMNASEEQ---KS 435
           +E LE+ NS+L  +  +L+  + S      +   L++E   L+E  L +  + E     S
Sbjct: 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCAS 717

Query: 436 MIVAQ----SKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEGR 481
           M +AQ    +K+LE+E   L   + +L+     T +R+  +   ++IE +
Sbjct: 718 MKMAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQ 766


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 34/114 (29%), Positives = 60/114 (52%), Gaps = 6/114 (5%)

Query: 362 ADLHFNKRKLEEENNKFK---LALETLEETNSQLSEDCTELRLQVKSAHQAIMR---TNL 415
           ++L    RKL++  + FK     LE+LE+ NSQL E+  ELR  V+S   A M+     L
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQL 725

Query: 416 LKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRI 469
             +ELE  K  +    E       ++++LE   + L ++ + LQ+ + ++ ++I
Sbjct: 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 33/136 (24%), Positives = 63/136 (46%), Gaps = 8/136 (5%)

Query: 364 LHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEEL 423
           L  + + L+ EN + +  LE   +   QL  +  +L ++ ++  + +    +  + LE+L
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813

Query: 424 KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRI-EIEGRL 482
           +    + E++ S +    KQLE EN+ L       Q E+ DT   +  N  +I  +E   
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRL-----RQQAEIKDT--TLEENNVKIGNLEKEN 866

Query: 483 KALHHEIALQLLTYIR 498
           K L  EI +   + +R
Sbjct: 867 KTLSKEIGIYKESCVR 882



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 31/176 (17%)

Query: 331 DITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLE---- 386
           ++T S L   E      +K V E+   +  V        K+E+EN +    +E LE    
Sbjct: 456 ELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIV 515

Query: 387 ------ETNSQLSEDCTELRLQVKSAHQAIMRTN-----LLKEELEELKLSMNASEEQKS 435
                 +    LS+D  + + Q++   + +   +     +L++E E L  ++ +S  Q+S
Sbjct: 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTV-SSLRQRS 574

Query: 436 MIVAQS--KQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEGR--LKALHH 487
            I A++  K +E EN       +IL E + +T  ++     +IE E R   K L H
Sbjct: 575 QISAEARVKDIEKEN-------KILHESIKETSSKL----SKIEFEKRQIKKELEH 619



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 6/125 (4%)

Query: 370 KLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM-- 427
           KLE EN      +E L  T   +  + +++    K   +   +  +L+ E+ + K S+  
Sbjct: 464 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN 523

Query: 428 --NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRI--VPNQFRIEIEGRLK 483
             N S++         K +ET       +I+IL++E     Q +  +  + +I  E R+K
Sbjct: 524 CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVK 583

Query: 484 ALHHE 488
            +  E
Sbjct: 584 DIEKE 588



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 12/102 (11%)

Query: 361 VADLHFNKRKLEEENNKFKLALETLEETNSQLSE--------DCTELRLQVKSAHQAIMR 412
           +A L    ++LE E  + K  LE L+ +  +           D    RLQ K+   +  +
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ-KTLENSNKK 778

Query: 413 TNLLKEELEELKLSMNASEEQKSMIVAQSK---QLETENRAL 451
              L+ EL++L++     ++    +   SK   QLE EN++L
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 27/141 (19%), Positives = 67/141 (47%), Gaps = 11/141 (7%)

Query: 321  KSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKL 380
            K + T+K S +I +  + + EA   E++    ++   +  V   +   ++ ++E      
Sbjct: 959  KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE------ 1012

Query: 381  ALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQ 440
              E + +++  +S +  +   + +   + +++   +K+ L E++ +    + +K  +  Q
Sbjct: 1013 --ERMVQSSPPISGEDNKWERESQETTRELLK---VKDRLIEVERNNATLQAEKQALKTQ 1067

Query: 441  SKQLETENRALILKIRILQEE 461
             KQLET+N  L  +I  LQ +
Sbjct: 1068 LKQLETQNNNLQAQILALQRQ 1088



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 11/99 (11%)

Query: 353 EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMR 412
           EVS     + D+ F K ++EE           L+E N  L E  T L  Q++       +
Sbjct: 328 EVSRYKERLHDIEFYKARVEE-----------LKEDNQVLLETKTMLEDQLEGTRARSDK 376

Query: 413 TNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL 451
            + L++E  +LK  ++  E ++ M   + ++L  EN  L
Sbjct: 377 LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL 415



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 11/110 (10%)

Query: 382 LETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEE---LEELKLSMNASEEQ---KS 435
           +E LE+ NS+L  +  +L+  + S      +   L++E   L+E  L +  + E     S
Sbjct: 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCAS 717

Query: 436 MIVAQ----SKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEGR 481
           M +AQ    +K+LE+E   L   + +L+     T +R+  +   ++IE +
Sbjct: 718 MKMAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQ 766


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2216

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2217 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2275

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2276 VAEEAARLSVAAQEAARLRQLA 2297



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1773



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2271 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2330

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2331 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2390

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2391 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2164 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2220

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2221 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2279

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2280 VAEEAARLSVAAQEAARLRQLA 2301



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1665 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1724

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1725 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1777



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2275 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2334

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2335 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2394

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2395 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2429


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2216

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2217 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2275

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2276 VAEEAARLSVAAQEAARLRQLA 2297



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1773



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2271 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2330

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2331 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2390

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2391 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2128 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2184

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2185 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2243

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2244 VAEEAARLSVAAQEAARLRQLA 2265



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1629 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1688

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1689 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1741



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2239 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2298

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2299 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2358

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2359 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2393


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2297 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2353

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2354 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2412

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2413 VAEEAARLSVAAQEAARLRQLA 2434



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1798 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1857

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1858 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1910



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2408 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2467

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2468 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2527

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2528 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2562


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2138 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2194

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2195 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2253

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2254 VAEEAARLSVAAQEAARLRQLA 2275



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1639 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1698

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1699 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1751



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2249 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2308

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2309 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2368

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2369 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2403


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2146 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2202

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2203 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2261

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2262 VAEEAARLSVAAQEAARLRQLA 2283



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1647 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1706

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1707 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1759



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2257 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2316

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2317 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2376

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2377 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2411


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 23/142 (16%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K+  + E  K K   E      +Q+ ++ T LRLQ++       + NLL EEL+ LK   
Sbjct: 2187 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH---QKNLLDEELQRLKAEA 2243

Query: 428  NASEEQKSMIVAQ--------------SKQLETENRALILK-----IRILQEEMSDTYQR 468
              +  Q+S +  +                ++E ENRALIL+      R LQEE ++  ++
Sbjct: 2244 TEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMKQ 2302

Query: 469  IVPNQFRIEIEGRLKALHHEIA 490
            +     R+ +  +  A   ++A
Sbjct: 2303 VAEEAARLSVAAQEAARLRQLA 2324



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
            E   Q  E   E R + K+  QA+ +  L ++ELE+ +     + +Q+     +  +L  
Sbjct: 1688 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1747

Query: 447  ENRALILKIRILQEEMSDTY-QRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
            E      + ++L+EE++    +     Q R E+E  L  +  E+ + L +  R
Sbjct: 1748 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1800



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 346  ETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLAL-ETLEETNSQLSEDCTELRLQVK 404
            E  K V E +  ++  A      R+L EE+   + AL E + +   Q  ++ T L+ + +
Sbjct: 2298 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAE 2357

Query: 405  SAHQ----AIMRTNLLKEELEEL--KLSMNASEEQKSMIVAQSKQLETENRALILKIRIL 458
               Q    A  +   L+E+ E++  +L+      Q+++   + +QLE    A  LK+R+ 
Sbjct: 2358 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2417

Query: 459  QEEMSDTYQRIVPNQFRIEIEGRLKALHH-EIALQ 492
            +   +         +FR + E   + LH  E+A Q
Sbjct: 2418 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2452


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/172 (23%), Positives = 84/172 (48%), Gaps = 20/172 (11%)

Query: 327  KMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLE 386
            KM  D+ ++TL           K    V++L   + +L   K+KLE+E ++FKL L+ + 
Sbjct: 1175 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1234

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
                Q+        ++ K+  + + RT  L+++  E ++ +  ++   +    Q  +L+T
Sbjct: 1235 SNMEQI--------IKAKANLEKVSRT--LEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284

Query: 447  ENRALILKI--------RILQEEMSDTYQRIVPNQFRIEIEGRLK-ALHHEI 489
            EN  L  ++        ++ + ++S T Q++   + ++E EG+ K AL H +
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYT-QQMEDLKRQLEEEGKAKNALAHAL 1335



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 58/269 (21%), Positives = 113/269 (42%), Gaps = 16/269 (5%)

Query: 193  WKQEADDGKEDVIYSINRACK-EEALTSIFNACDIKRKELICSSFSKGSVGVAKIINFLR 251
            WKQ+ ++ + ++  S   A      L  + NA +   + L   +F + +  + + I+ L 
Sbjct: 1458 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL--ETFKRENKNLQEEISDLT 1515

Query: 252  QTTSQNSED-SGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSII 310
            +   +  ++   LE++   L+ EK +    LE  +A ++             N ++ + I
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN-QIKAEI 1574

Query: 311  DDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVS-----DLIAYVADLH 365
            +  + E+D  + +   +    + DS   S +A     ++ VL V      DL      L 
Sbjct: 1575 ERKLAEKDE-EMEQAKRNHQRVVDSLQTSLDAETRSRNE-VLRVKKKMEGDLNEMEIQLS 1632

Query: 366  FNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAI-MRTNLLKEELEELK 424
               R   E   + K     L++T  QL +D       +K     +  R NLL+ ELEEL+
Sbjct: 1633 HANRMAAEAQKQVKSLQSLLKDTQIQL-DDAVRANDDLKENIAIVERRNNLLQAELEELR 1691

Query: 425  LSMNASEEQKSMIVAQSKQLETENRALIL 453
              +  +E  + +  A+ + +ET  R  +L
Sbjct: 1692 AVVEQTERSRKL--AEQELIETSERVQLL 1718



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 63/329 (19%), Positives = 137/329 (41%), Gaps = 21/329 (6%)

Query: 113  ILTSSENVSKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQS 172
            + ++ E + K K+   K   +L  Q   A  +  K      S N+F+T      +   + 
Sbjct: 1233 VTSNMEQIIKAKANLEKVSRTLEDQ---ANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289

Query: 173  LKCFDPQDSVVKKLSLNEDGWKQEADDGKEDVIYSIN-RACKEEALTSIFNACDIKRKEL 231
             +  + +++++ +L+  +  + Q+ +D K  +      +     AL S  + CD+ R++ 
Sbjct: 1290 ARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQ- 1348

Query: 232  ICSSFSKGSVGVAKIINFLRQTTSQNSE-----DSGLEQLWNMLDPEKRDPHVDLETFQA 286
                + + +   A++   L +  S+ ++     ++   Q    L+  K+     L+  + 
Sbjct: 1349 ----YEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404

Query: 287  MMKDWMAYCGNTWEGVNHRLSSIIDDSVC--EQDGIKSDGTMKMSTDITDSTLGSFEALG 344
             ++   A C +  E   HRL + I+D +   E+    +    K   +  D  L  ++   
Sbjct: 1405 AVEAVNAKCSSL-EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF-DKILAEWKQKY 1462

Query: 345  GETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVK 404
             E S+  LE S   A    L     KL+    +    LET +  N  L E+ ++L  Q+ 
Sbjct: 1463 -EESQSELESSQKEA--RSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1519

Query: 405  SAHQAIMRTNLLKEELEELKLSMNASEEQ 433
               + +     ++++LE  KL + ++ E+
Sbjct: 1520 EGGKNVHELEKVRKQLEVEKLELQSALEE 1548



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 26/132 (19%), Positives = 64/132 (48%), Gaps = 6/132 (4%)

Query: 362  ADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELE 421
            A+L   KRKLE+E ++ K  ++ LE T +++ ++      +VK+  + +   + +  +L 
Sbjct: 936  AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995

Query: 422  ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQ--FRIEIE 479
            + K ++  + +Q         Q+E +    + K ++  E+  D  +  +  +   R+++E
Sbjct: 996  KEKKALQEAHQQ----ALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLE 1051

Query: 480  GRLKALHHEIAL 491
               + L  ++ L
Sbjct: 1052 RAKRKLEGDLKL 1063


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 42/227 (18%), Positives = 104/227 (45%), Gaps = 22/227 (9%)

Query: 243  VAKIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGV 302
            ++ + N +R+ T   +E   +E++  +++ EK +  V LE  +  ++       N  + +
Sbjct: 1521 ISNLTNQVREGTKNLTE---MEKVKKLIEEEKTEVQVTLEETEGALER------NESKIL 1571

Query: 303  NHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVA 362
            + +L  +   +  E+   + D  ++        T+ S ++     +K  +EV+ L     
Sbjct: 1572 HFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRL----- 1626

Query: 363  DLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEE 422
                 K+K+EE+ N+ +L L       S+ ++   +L++Q+K     +  +  L  +L+E
Sbjct: 1627 -----KKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKE 1681

Query: 423  LKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRI 469
                +  +E + S++ ++ + L +         R+ +EE+ +  +RI
Sbjct: 1682 ---QVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERI 1725



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 21/75 (28%), Positives = 42/75 (56%), Gaps = 1/75 (1%)

Query: 416 LKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIV-PNQF 474
           LKEE  +L+ ++  SE Q+  + A+   L  E   LIL+++  QE +++  ++     + 
Sbjct: 864 LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKS 923

Query: 475 RIEIEGRLKALHHEI 489
           +I++E R+K L   +
Sbjct: 924 KIQLEARVKELSERV 938



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 363 DLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEE 422
           +L   +  L +E N   L L+  +ET + + E C  L   +KS  Q   R   L E +EE
Sbjct: 884 ELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWL---IKSKIQLEARVKELSERVEE 940

Query: 423 LKLSMNASEEQKSMIVAQSKQLETE 447
                   EE  S + A+ ++LE E
Sbjct: 941 -------EEEINSELTARGRKLEDE 958



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 31/139 (22%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 300  EGVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGG-----ETSKGVLEV 354
            E   H+L   + D++ +   ++S      +  +    L S +AL       E S+ +L+ 
Sbjct: 1427 ERARHQLQLELGDALSDLGKVRS-----AAARLDQKQLQSGKALADWKQKHEESQALLDA 1481

Query: 355  SDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTN 414
            S     V  L     KL+    +  +  ETL   N  L E+ + L  QV+   + +    
Sbjct: 1482 SQ--KEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539

Query: 415  LLKEELEELKLSMNASEEQ 433
             +K+ +EE K  +  + E+
Sbjct: 1540 KVKKLIEEEKTEVQVTLEE 1558


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 35/158 (22%), Positives = 70/158 (44%), Gaps = 17/158 (10%)

Query: 353 EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIM- 411
           ++S+  A + DL  +   L     K    L+TLE    Q  E+C ++  Q+K AH+A + 
Sbjct: 667 DLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE 726

Query: 412 ---------RTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEM 462
                    R   L+ E+   K   + ++ +   ++   K++E E      KI  L+ ++
Sbjct: 727 ARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 786

Query: 463 SDTYQRIVPNQFRIEIEGRLKALHHEIALQLLTYIRKR 500
            D  +++   + + ++E +  A       Q+L   R+R
Sbjct: 787 KDQNKKVANLKHKEQVEKKKSA-------QMLEEARRR 817



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 20/130 (15%)

Query: 351 VLEVSDLIAYVADLHFNKRKLEEENNKFKL--ALETLEETNSQLSEDCTELRLQVKSAHQ 408
           V+E+ D  + ++ +    R LEEE    K   AL T EE   ++ +      ++V  +H 
Sbjct: 383 VIEMKD--SKISSMERGLRDLEEEIQMLKSNGALST-EEREEEMKQ------MEVYRSHS 433

Query: 409 AIMRTNL--LKEEL-------EELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQ 459
             M+  +  LKEEL       EELK      + +   +  +  + +TE  AL  K+  L 
Sbjct: 434 KFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLT 493

Query: 460 EEMSDTYQRI 469
            + SD+ Q I
Sbjct: 494 NQFSDSKQHI 503



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 15/119 (12%)

Query: 370 KLEEE----NNKFKLALETLEETNSQLSE--DCTELRLQVKSAHQAIMRTNLLKEELEEL 423
           +LEE+    N K K   +  EE  +Q  E  D  ++ L VK       + N+L++++E L
Sbjct: 530 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM-LDVKER-----KVNVLQKKIENL 583

Query: 424 KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD---TYQRIVPNQFRIEIE 479
           +  +   E+Q S +  + K L+ +       +  L+E +++   T +R+   + R E E
Sbjct: 584 QEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 642


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 35/158 (22%), Positives = 70/158 (44%), Gaps = 17/158 (10%)

Query: 353 EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIM- 411
           ++S+  A + DL  +   L     K    L+TLE    Q  E+C ++  Q+K AH+A + 
Sbjct: 639 DLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE 698

Query: 412 ---------RTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEM 462
                    R   L+ E+   K   + ++ +   ++   K++E E      KI  L+ ++
Sbjct: 699 ARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 758

Query: 463 SDTYQRIVPNQFRIEIEGRLKALHHEIALQLLTYIRKR 500
            D  +++   + + ++E +  A       Q+L   R+R
Sbjct: 759 KDQNKKVANLKHKEQVEKKKSA-------QMLEEARRR 789



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 15/119 (12%)

Query: 370 KLEEE----NNKFKLALETLEETNSQLSE--DCTELRLQVKSAHQAIMRTNLLKEELEEL 423
           +LEE+    N K K   +  EE  +Q  E  D  ++ L VK       + N+L++++E L
Sbjct: 502 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM-LDVKER-----KVNVLQKKIENL 555

Query: 424 KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD---TYQRIVPNQFRIEIE 479
           +  +   E+Q S +  + K L+ +       +  L+E +++   T +R+   + R E E
Sbjct: 556 QEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 614


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 46/186 (24%), Positives = 84/186 (45%), Gaps = 33/186 (17%)

Query: 326  MKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKL----- 380
            +K+  D+ ++TL     +     K    V++L   + +L   K+KLE+E ++FKL     
Sbjct: 1173 LKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDL 1232

Query: 381  --ALETLEETNSQLSEDCTELRLQVKSA---HQAIMRTNLLKEELEELKLSMNASE---- 431
              ++E++ ++ + L + C  L  Q+  A   ++ I R +L +   ++ +L   A E    
Sbjct: 1233 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR-SLSELTTQKSRLQTEAGELSRQ 1291

Query: 432  -EQKSMIVAQ---------------SKQLETENRALILKIRILQEEMSDTYQRIVPNQFR 475
             E+K  IV+Q                +QLE EN+A       LQ    D    ++  Q+ 
Sbjct: 1292 LEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDC--DLLREQYE 1349

Query: 476  IEIEGR 481
             E EG+
Sbjct: 1350 EEQEGK 1355



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 10/122 (8%)

Query: 362  ADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELE 421
            A+L   KRKLE+E ++ K  ++ LE T +++           K  H    +   L EEL 
Sbjct: 935  AELTAKKRKLEDECSELKKDIDDLELTLAKVE----------KEKHATENKVKNLTEELS 984

Query: 422  ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEGR 481
             L  ++     +K  +    +Q   + +A   K+  L +  S   Q++   +  +E E +
Sbjct: 985  GLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKK 1044

Query: 482  LK 483
            L+
Sbjct: 1045 LR 1046



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 25/116 (21%), Positives = 58/116 (50%), Gaps = 3/116 (2%)

Query: 349 KGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQ 408
           K +L+ ++    +A +    +K ++E  K +   + LEE    L ++  +L+LQV++  +
Sbjct: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE 897

Query: 409 AIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            ++      ++L + K  + A  ++   +  +++  E  N  L  K R L++E S+
Sbjct: 898 NLLDAEERCDQLIKAKFQLEAKIKE---VTERAEDEEEINAELTAKKRKLEDECSE 950



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 48/218 (22%), Positives = 88/218 (40%), Gaps = 18/218 (8%)

Query: 245  KIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNH 304
            +I +   Q          LE+    ++ EK D  + LE  +A ++   A        +  
Sbjct: 1509 EIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT- 1567

Query: 305  RLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADL 364
            ++ S ID  + E+D  +    +K +   T  T+ S  AL  E       +        DL
Sbjct: 1568 QVKSEIDRKIAEKD--EEIEQLKRNYQRTVETMQS--ALDAEVRSRNEAIRLKKKMEGDL 1623

Query: 365  HFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIM---------RTNL 415
            +  + +L   N +    L+ L     QL +  T+L L      Q  +         R NL
Sbjct: 1624 NEIEIQLSHANRQAAETLKHLRSVQGQLKD--TQLHLDDALRGQEDLKEQLAIVERRANL 1681

Query: 416  LKEELEELKLSMNASEEQKSMIVAQSKQLETENRALIL 453
            L+ E+EEL+ ++  +E  + +  A+ + L++  R  +L
Sbjct: 1682 LQAEVEELRATLEQTERARKL--AEQELLDSNERVQLL 1717


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 21/94 (22%), Positives = 47/94 (50%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            +R +E+E NK+K+ ++   +T  Q+    T    +++           L+ E E L++ +
Sbjct: 1131 QRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMEL 1190

Query: 428  NASEEQKSMIVAQSKQLETENRALILKIRILQEE 461
              +E ++S  V + ++L+ +    + K+R  Q E
Sbjct: 1191 EKAEMERSTYVTEVRELKAQLNETLTKLRTEQNE 1224


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 21/94 (22%), Positives = 47/94 (50%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            +R +E+E NK+K+ ++   +T  Q+    T    +++           L+ E E L++ +
Sbjct: 1125 QRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMEL 1184

Query: 428  NASEEQKSMIVAQSKQLETENRALILKIRILQEE 461
              +E ++S  V + ++L+ +    + K+R  Q E
Sbjct: 1185 EKAEMERSTYVTEVRELKAQLNETLTKLRTEQNE 1218



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 32/156 (20%), Positives = 65/156 (41%), Gaps = 11/156 (7%)

Query: 312 DSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKL 371
           + + E + +K     K   D+        E +G    +   ++S + + V +L    +  
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS-ITSKVQELQNLLKGK 872

Query: 372 EEENNKFKLALETLEETNSQ-------LSEDCTELRLQVKSAHQAIMRTNLLKEELEELK 424
           EE+ N  K  LE  E+  +        L E+   L+  V+   Q  ++      + EEL+
Sbjct: 873 EEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 932

Query: 425 LSMNASEEQKSMIVAQSKQLETENRALILKIRILQE 460
           + +   E +   + A  K+ E++   L  K ++LQ+
Sbjct: 933 IVLKEKENELKRLEAMLKERESD---LSSKTQLLQD 965


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
           sapiens]
          Length = 1478

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 73/377 (19%), Positives = 155/377 (41%), Gaps = 35/377 (9%)

Query: 105 PETATYSVILTSSENVSKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSEN---NFSTL 161
           P  A  ++   SS  + KP S+S+   + + S ++  E  SN DLN+  +      F  +
Sbjct: 176 PTFARRTLTTGSSAYLWKPPSRSSSMSSLVSSYLQTQEMVSNFDLNSPLNNEALEGFDEM 235

Query: 162 TLDFDSTFVQSLKCFDPQDSVVKKLSLNEDGWKQEADDGKEDVIYSINRACKEEALTSIF 221
            L+ D   V+  +  +    + ++         Q+ +  + +      R   E+ +    
Sbjct: 236 RLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTE--RERGRTAAEDNVRLTC 293

Query: 222 NACDIKRKELICSSFSKGSVGVAKIINFLRQTTSQNSED--SGLEQLWNMLDPEKRDPHV 279
              +++++  +  +       +   +  L    ++  ED  + L +L +ML P  ++   
Sbjct: 294 LVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEA 353

Query: 280 DLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKSDGTMKMSTDITDSTLGS 339
             ++     +   ++ G  W  +  + +    D+   Q+ I SD   +M        LG 
Sbjct: 354 TRDSLDKKNQHLASFPG--WLAMAQQKADTASDTKGRQEPIPSDAAQEMQE------LGE 405

Query: 340 -FEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENN----KFKLALETLEETNSQLSE 394
             +AL  E +K V EV+   +   +    + +L+E+      +    +  L+E  S   +
Sbjct: 406 KLQALERERTK-VEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQ 464

Query: 395 DCTEL--RLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALI 452
           +  +L  RLQ   AH     T+  +EEL EL+      +E+K +       LE E R+L 
Sbjct: 465 EADQLWRRLQELLAH-----TSSWEEELAELRREKKQQQEEKEL-------LEQEVRSLT 512

Query: 453 LKIRILQEEMSDTYQRI 469
            +++ L+ +++   Q +
Sbjct: 513 RQLQFLETQLAQVSQHV 529



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 6/109 (5%)

Query: 361  VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAI--MRTNLLKE 418
            VA L   K  L+E+    K A  +L    +QL++     +   ++AHQ +  ++  L  E
Sbjct: 951  VAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAE 1010

Query: 419  ELEELKLSMNASEEQKSM---IVAQSKQLETENRALILKIRILQEEMSD 464
             ++      NA EE KS+   +  Q +QL+    A + K++  Q +M +
Sbjct: 1011 IMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEA-VEKLKATQADMGE 1058


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 60/264 (22%), Positives = 119/264 (45%), Gaps = 29/264 (10%)

Query: 253  TTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDD 312
            T + NS+ + LE+    L  E  D   DLE              N ++ V       +D+
Sbjct: 1408 TETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRN-FDKVLAEWKQKLDE 1466

Query: 313  SVCEQDGIKSDGTMKMSTDIT------DSTLGSFEALGGETSKGVLEVSDLIAYVADLHF 366
            S  E +  + + +  +ST++       +  +   E L  E      E+SDL   +A+   
Sbjct: 1467 SQAELEAAQKE-SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGK 1525

Query: 367  N-------KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLK-E 418
            N       K+ +E+E +  ++ALE +E +          ++L++      + R  + K E
Sbjct: 1526 NLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDE 1585

Query: 419  ELEELKL-SMNASEEQKSMIVAQSKQLETENRALILKIRI------LQEEMSDTYQRIVP 471
            E+E+LK  S  A+E  +S++ A   ++ + N AL LK ++      ++ ++  + +++  
Sbjct: 1586 EIEQLKRNSQRAAEALQSVLDA---EIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAE 1642

Query: 472  NQFRIE-IEGRLK--ALHHEIALQ 492
             Q  +  ++G+LK   LH + AL+
Sbjct: 1643 TQKHLRTVQGQLKDSQLHLDDALR 1666



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 33/152 (21%), Positives = 68/152 (44%), Gaps = 17/152 (11%)

Query: 327  KMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLA----- 381
            KM  D+ ++TL           K    V++L   + +L   K+KLE+E ++ K+      
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMA 1236

Query: 382  --LETLEETNSQLSEDC-------TELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEE 432
              +E L ++ S +   C       +E++ + +   Q I   N+ K  L+     ++   E
Sbjct: 1237 SNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVE 1296

Query: 433  QKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            +K  +++   QL    +AL  ++  L+ +M +
Sbjct: 1297 EKESLIS---QLTKSKQALTQQLEELKRQMEE 1325



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 27/114 (23%), Positives = 56/114 (49%), Gaps = 11/114 (9%)

Query: 349 KGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQ 408
           K +L+ ++    +A +  +  + +EE  + +   + LEE    L ++  +L+LQV+S  +
Sbjct: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900

Query: 409 AIMRTN-----------LLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL 451
            +M              LL+ +++EL   +   EE  S +VA+ + LE +  +L
Sbjct: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSL 954



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 40/163 (24%), Positives = 73/163 (44%), Gaps = 22/163 (13%)

Query: 310  IDDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKR 369
            +DD   E+D  K +G +K++  +   T         +  +G LE    +   ADL   KR
Sbjct: 1011 LDDLQVEED--KVNGLIKINAKLEQQT---------DDLEGSLEQEKKLR--ADLERAKR 1057

Query: 370  KLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNA 429
            KLE +    + ++  LE    Q+ E     +L+ K    + ++  +  E++  L+     
Sbjct: 1058 KLEGDLKMSQESIMDLENDKQQIEE-----KLKKKEFELSQLQAKIDDEQVHSLQFQKKI 1112

Query: 430  SEEQKSMIVAQSKQLETEN--RALILKIRI-LQEEMSDTYQRI 469
             E Q + I    +++E E+  RA I K R  L  E+ +  +R+
Sbjct: 1113 KELQ-ARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERL 1154


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 327  KMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLE 386
            KM  D+ ++TL           K    V++L   + +L   K+KLE+E ++FKL L+ + 
Sbjct: 1173 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232

Query: 387  ETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLET 446
                Q+        ++ K+  + + RT  L++++ E +     ++   + + +Q  +L+T
Sbjct: 1233 SNMEQI--------IKAKANLEKMCRT--LEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282

Query: 447  ENRAL 451
            EN  L
Sbjct: 1283 ENGEL 1287



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 73/394 (18%), Positives = 161/394 (40%), Gaps = 40/394 (10%)

Query: 113  ILTSSENVSKPKSQSNKNYTSLMSQIRKAEFFSNKDLNNYCSENNFSTLTLDFDSTFVQS 172
            + ++ E + K K+   K   +L  Q+ +     +K      S N+ ++      +   + 
Sbjct: 1231 VTSNMEQIIKAKANLEKMCRTLEDQMNEHR---SKAEETQRSVNDLTSQRAKLQTENGEL 1287

Query: 173  LKCFDPQDSVVKKLSLNEDGWKQEADDGKEDVIYSIN-RACKEEALTSIFNACDIKRKEL 231
             +  D +++++ +L+  +  + Q+ +D K  +   +  +     AL S  + CD+ R++ 
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQ- 1346

Query: 232  ICSSFSKGSVGVAKIINFLRQTTSQNSE-----DSGLEQLWNMLDPEKRDPHVDLETFQA 286
                + + +   A++   L +  S+ ++     ++   Q    L+  K+     L+  + 
Sbjct: 1347 ----YEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402

Query: 287  MMKDWMAYCGNTWEGVNHRLSSIIDDSVC--EQDGIKSDGTMKMSTDITDSTLGSFEALG 344
             ++   A C +  E   HRL + I+D +   E+    +    K   +  D  L  ++   
Sbjct: 1403 AVEAVNAKCSSL-EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF-DKILAEWKQKY 1460

Query: 345  GETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVK 404
             E S+  LE S   A    L     KL+    +    LET +  N  L E+ ++L  Q+ 
Sbjct: 1461 -EESQSELESSQKEA--RSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517

Query: 405  SAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            S+ + I     ++++LE  K+ + ++ E+     A++     E + L  ++         
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEE-----AEASLEHEEGKILRAQLEF------- 1565

Query: 465  TYQRIVPNQFRIEIEGRLKALHHEIALQLLTYIR 498
                   NQ + EIE +L     E+      ++R
Sbjct: 1566 -------NQIKAEIERKLAEKDEEMEQAKRNHLR 1592



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 57/268 (21%), Positives = 109/268 (40%), Gaps = 14/268 (5%)

Query: 193  WKQEADDGKEDVIYSINRACK-EEALTSIFNACDIKRKELICSSFSKGSVGVAKIINFL- 250
            WKQ+ ++ + ++  S   A      L  + NA +   + L   +F + +  + + I+ L 
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL--ETFKRENKNLQEEISDLT 1513

Query: 251  RQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSII 310
             Q  S       LE++   L+ EK +    LE  +A ++             N ++ + I
Sbjct: 1514 EQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFN-QIKAEI 1572

Query: 311  DDSVCEQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVS----DLIAYVADLHF 366
            +  + E+D  + +   +    + DS   S +A     ++ +        DL      L  
Sbjct: 1573 ERKLAEKDE-EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631

Query: 367  NKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAI-MRTNLLKEELEELKL 425
              R   E   + K     L++T  QL +D       +K     +  R NLL+ ELEEL+ 
Sbjct: 1632 ANRMAAEAQKQVKSLQSLLKDTQIQL-DDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690

Query: 426  SMNASEEQKSMIVAQSKQLETENRALIL 453
             +  +E  + +  A+ + +ET  R  +L
Sbjct: 1691 VVEQTERSRKL--AEQELIETSERVQLL 1716



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 26/132 (19%), Positives = 63/132 (47%), Gaps = 6/132 (4%)

Query: 362  ADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELE 421
            A+L   KRKLE+E ++ K  ++ LE T +++ ++      +VK+  + +   + +  +L 
Sbjct: 934  AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993

Query: 422  ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQ--FRIEIE 479
            + K ++  + +Q         Q E +    + K ++  E+  D  +  +  +   R+++E
Sbjct: 994  KEKKALQEAHQQ----ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 480  GRLKALHHEIAL 491
               + L  ++ L
Sbjct: 1050 RAKRKLEGDLKL 1061


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 17/117 (14%)

Query: 368 KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
           K  L +E+    + L   E     LSE+ T LRL                 E E L+ S+
Sbjct: 871 KEALAKEHAGLAVQLVAAEREGRTLSEEATRLRL-----------------EKEALEGSL 913

Query: 428 NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQFRIEIEGRLKA 484
              + Q + + A+ +QLE E +AL+L    L  E++   Q+I+  Q +  ++  L A
Sbjct: 914 FEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMA 970



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 25/131 (19%), Positives = 58/131 (44%), Gaps = 7/131 (5%)

Query: 321 KSDGTMKMSTDI---TDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNK 377
           K+DG M+   D          + E L  E S     +        +L   + KL+    +
Sbjct: 576 KTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEE 635

Query: 378 FKLALETLEETNSQLSEDCTELRLQVKSAHQAIM----RTNLLKEELEELKLSMNASEEQ 433
            +   + LEE      +D   +R +++ +H+ +     + ++L +EL E++ +++ +  Q
Sbjct: 636 LRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQ 695

Query: 434 KSMIVAQSKQL 444
           + M+ A+  ++
Sbjct: 696 RDMLQAEKAEV 706


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 11/129 (8%)

Query: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKS-------AHQAIMRTNLLKEELE 421
           +K +E   K +  L+ LE+ +SQL+E+   L+ Q+++       A +  +R    K+ELE
Sbjct: 862 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921

Query: 422 ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQF-RIEIEG 480
           E+   M A  E++     + +QL+ E + +  ++  L+E++ +        Q  ++  E 
Sbjct: 922 EILHEMEARLEEEE---DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978

Query: 481 RLKALHHEI 489
           ++K L  EI
Sbjct: 979 KIKKLEDEI 987



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 5/136 (3%)

Query: 316  EQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEEN 375
            +Q  + +    K+  D+ D  L +  A+ G   + + ++  L A + D            
Sbjct: 1610 KQRALAAAAKKKLEGDLKDLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASR 1668

Query: 376  NKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL-EELKLSM---NASE 431
            ++     +  E+    L  D  +L+  + +A +A  + +L KEEL EEL  S+   NA +
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728

Query: 432  EQKSMIVAQSKQLETE 447
            ++K  + A+  QLE E
Sbjct: 1729 DEKRRLEARIAQLEEE 1744



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 17/139 (12%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K++LEE  ++ +  LE  E+   QL  +  ++  Q+            L+E+LEE + + 
Sbjct: 917  KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD----------LEEQLEEEEAAR 966

Query: 428  NASEEQKSMIVAQSKQLETE-------NRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
               + +K    A+ K+LE E       N  L  + ++L+E +SD    +   + + +   
Sbjct: 967  QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026

Query: 481  RLKALHHEIALQLLTYIRK 499
            +LK  H  +  +L   ++K
Sbjct: 1027 KLKNKHESMISELEVRLKK 1045



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 58/264 (21%), Positives = 109/264 (41%), Gaps = 44/264 (16%)

Query: 245  KIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNH 304
            +I N  +Q   + +    LE+  N L  E  D  VDL+  + ++ + +      ++ +  
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN-LEKKQRKFDQLLA 1458

Query: 305  RLSSIIDDSVCEQDGIKSDGTMKMSTDIT-----DSTLGSFEALGGETSKGVLEVSDLIA 359
               +I      E+D  +++   K +  ++     +  L + E L         E+ DL++
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518

Query: 360  Y-------VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSA------ 406
                    V +L  +KR LE +  + K  LE LE+   Q +ED  +LRL+V         
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATED-AKLRLEVNMQALKGQF 1576

Query: 407  --------HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL------- 451
                     Q   +   L+ +L E +  +    +Q+++  A  K+LE + + L       
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636

Query: 452  -------ILKIRILQEEMSDTYQR 468
                   I ++R LQ +M D +QR
Sbjct: 1637 IKGREEAIKQLRKLQAQMKD-FQR 1659



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 10/105 (9%)

Query: 343  LGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQ 402
            L G+ S    +++DL A +A+L     K EEE          L+   ++L ++  +    
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEE----------LQAALARLDDEIAQKNNA 1109

Query: 403  VKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
            +K   +     + L+E+L+  + + N +E+QK  +  + + L+TE
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 20/100 (20%), Positives = 49/100 (49%)

Query: 364  LHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEEL 423
            LH  + +LE+E  +  LA    ++    L +   +    +K   +AI +   L+ ++++ 
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 1657

Query: 424  KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMS 463
            +  +  +   +  I A +K+ E + ++L   +  LQE+++
Sbjct: 1658 QRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1697



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 341  EALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELR 400
            E  G   SK    ++ L A +A L   + ++E+E  + + A ++L++ + +L E   ++ 
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQL---EEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 1859

Query: 401  LQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
             + K A Q   +       +++LK  +  +EE+   I A  ++L+ E
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 13/101 (12%)

Query: 369  RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM- 427
            R+LEEE N  +  L+   E    L    + L +Q+  + + +       E LEE K    
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398

Query: 428  ----NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
                N +++ +    A  K  +T+NR        LQ+E+ D
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNR--------LQQELDD 1431



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 27/207 (13%)

Query: 263  LEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKS 322
            LE+L   L+ +  D H  +   QA + +         E +   L+ + D+   + + +K 
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1112

Query: 323  DGTMKMSTDITDSTLGSFEA-----------LGGETSKGVLEVSDLIAYVADLHFNKRKL 371
               ++         L S  A           LG E      E+ D +   A     + K 
Sbjct: 1113 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1172

Query: 372  EEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASE 431
            E+E    K AL+  EET S  ++   E+R +   A +       L E+LE+ K +     
Sbjct: 1173 EQEVTVLKKALD--EETRSHEAQ-VQEMRQKHAQAVEE------LTEQLEQFKRA----- 1218

Query: 432  EQKSMIVAQSKQLETENRALILKIRIL 458
              K+ +    + LE EN  L  ++R+L
Sbjct: 1219 --KANLDKNKQTLEKENADLAGELRVL 1243



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 10/118 (8%)

Query: 354  VSDLIAYVADLHFNKRKLEEENNKFKLALETLE-------ETNSQLSEDCTELRLQVKSA 406
            +SDL   +A+     + L +  NK +  +  LE       ++  +L +   +L       
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067

Query: 407  HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            H+ I     L+ ++ ELK+ +   EE+    +A+      +    + KIR L+  +SD
Sbjct: 1068 HEQIAD---LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1122


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 11/129 (8%)

Query: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKS-------AHQAIMRTNLLKEELE 421
           +K +E   K +  L+ LE+ +SQL+E+   L+ Q+++       A +  +R    K+ELE
Sbjct: 869 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928

Query: 422 ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQF-RIEIEG 480
           E+   M A  E++     + +QL+ E + +  ++  L+E++ +        Q  ++  E 
Sbjct: 929 EILHEMEARLEEEE---DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 985

Query: 481 RLKALHHEI 489
           ++K L  EI
Sbjct: 986 KIKKLEDEI 994



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 5/136 (3%)

Query: 316  EQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEEN 375
            +Q  + +    K+  D+ D  L +  A+ G   + + ++  L A + D            
Sbjct: 1617 KQRALAAAAKKKLEGDLKDLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASR 1675

Query: 376  NKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL-EELKLSM---NASE 431
            ++     +  E+    L  D  +L+  + +A +A  + +L KEEL EEL  S+   NA +
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1735

Query: 432  EQKSMIVAQSKQLETE 447
            ++K  + A+  QLE E
Sbjct: 1736 DEKRRLEARIAQLEEE 1751



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 17/139 (12%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K++LEE  ++ +  LE  E+   QL  +  ++  Q+            L+E+LEE + + 
Sbjct: 924  KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD----------LEEQLEEEEAAR 973

Query: 428  NASEEQKSMIVAQSKQLETE-------NRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
               + +K    A+ K+LE E       N  L  + ++L+E +SD    +   + + +   
Sbjct: 974  QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033

Query: 481  RLKALHHEIALQLLTYIRK 499
            +LK  H  +  +L   ++K
Sbjct: 1034 KLKNKHESMISELEVRLKK 1052



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 58/264 (21%), Positives = 109/264 (41%), Gaps = 44/264 (16%)

Query: 245  KIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNH 304
            +I N  +Q   + +    LE+  N L  E  D  VDL+  + ++ + +      ++ +  
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN-LEKKQRKFDQLLA 1465

Query: 305  RLSSIIDDSVCEQDGIKSDGTMKMSTDIT-----DSTLGSFEALGGETSKGVLEVSDLIA 359
               +I      E+D  +++   K +  ++     +  L + E L         E+ DL++
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525

Query: 360  Y-------VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSA------ 406
                    V +L  +KR LE +  + K  LE LE+   Q +ED  +LRL+V         
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATED-AKLRLEVNMQALKGQF 1583

Query: 407  --------HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL------- 451
                     Q   +   L+ +L E +  +    +Q+++  A  K+LE + + L       
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643

Query: 452  -------ILKIRILQEEMSDTYQR 468
                   I ++R LQ +M D +QR
Sbjct: 1644 IKGREEAIKQLRKLQAQMKD-FQR 1666



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 10/105 (9%)

Query: 343  LGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQ 402
            L G+ S    +++DL A +A+L     K EEE          L+   ++L ++  +    
Sbjct: 1067 LEGDASDFHEQIADLQAQIAELKMQLAKKEEE----------LQAALARLDDEIAQKNNA 1116

Query: 403  VKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
            +K   +     + L+E+L+  + + N +E+QK  +  + + L+TE
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1161



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 20/100 (20%), Positives = 49/100 (49%)

Query: 364  LHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEEL 423
            LH  + +LE+E  +  LA    ++    L +   +    +K   +AI +   L+ ++++ 
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 1664

Query: 424  KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMS 463
            +  +  +   +  I A +K+ E + ++L   +  LQE+++
Sbjct: 1665 QRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1704



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 341  EALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELR 400
            E  G   SK    ++ L A +A L   + ++E+E  + + A ++L++ + +L E   ++ 
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQL---EEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 1866

Query: 401  LQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
             + K A Q   +       +++LK  +  +EE+   I A  ++L+ E
Sbjct: 1867 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 13/101 (12%)

Query: 369  RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM- 427
            R+LEEE N  +  L+   E    L    + L +Q+  + + +       E LEE K    
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405

Query: 428  ----NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
                N +++ +    A  K  +T+NR        LQ+E+ D
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNR--------LQQELDD 1438



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 27/207 (13%)

Query: 263  LEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKS 322
            LE+L   L+ +  D H  +   QA + +         E +   L+ + D+   + + +K 
Sbjct: 1060 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1119

Query: 323  DGTMKMSTDITDSTLGSFEA-----------LGGETSKGVLEVSDLIAYVADLHFNKRKL 371
               ++         L S  A           LG E      E+ D +   A     + K 
Sbjct: 1120 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1179

Query: 372  EEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASE 431
            E+E    K AL+  EET S  ++   E+R +   A +       L E+LE+ K +     
Sbjct: 1180 EQEVTVLKKALD--EETRSHEAQ-VQEMRQKHAQAVEE------LTEQLEQFKRA----- 1225

Query: 432  EQKSMIVAQSKQLETENRALILKIRIL 458
              K+ +    + LE EN  L  ++R+L
Sbjct: 1226 --KANLDKNKQTLEKENADLAGELRVL 1250



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 10/118 (8%)

Query: 354  VSDLIAYVADLHFNKRKLEEENNKFKLALETLE-------ETNSQLSEDCTELRLQVKSA 406
            +SDL   +A+     + L +  NK +  +  LE       ++  +L +   +L       
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074

Query: 407  HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            H+ I     L+ ++ ELK+ +   EE+    +A+      +    + KIR L+  +SD
Sbjct: 1075 HEQIAD---LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1129


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 11/129 (8%)

Query: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKS-------AHQAIMRTNLLKEELE 421
           +K +E   K +  L+ LE+ +SQL+E+   L+ Q+++       A +  +R    K+ELE
Sbjct: 869 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928

Query: 422 ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQF-RIEIEG 480
           E+   M A  E++     + +QL+ E + +  ++  L+E++ +        Q  ++  E 
Sbjct: 929 EILHEMEARLEEEE---DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 985

Query: 481 RLKALHHEI 489
           ++K L  EI
Sbjct: 986 KIKKLEDEI 994



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 5/136 (3%)

Query: 316  EQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEEN 375
            +Q  + +    K+  D+ D  L +  A+ G   + + ++  L A + D            
Sbjct: 1617 KQRALAAAAKKKLEGDLKDLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASR 1675

Query: 376  NKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL-EELKLSM---NASE 431
            ++     +  E+    L  D  +L+  + +A +A  + +L KEEL EEL  S+   NA +
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1735

Query: 432  EQKSMIVAQSKQLETE 447
            ++K  + A+  QLE E
Sbjct: 1736 DEKRRLEARIAQLEEE 1751



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 17/139 (12%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K++LEE  ++ +  LE  E+   QL  +  ++  Q+            L+E+LEE + + 
Sbjct: 924  KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD----------LEEQLEEEEAAR 973

Query: 428  NASEEQKSMIVAQSKQLETE-------NRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
               + +K    A+ K+LE E       N  L  + ++L+E +SD    +   + + +   
Sbjct: 974  QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033

Query: 481  RLKALHHEIALQLLTYIRK 499
            +LK  H  +  +L   ++K
Sbjct: 1034 KLKNKHESMISELEVRLKK 1052



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 58/264 (21%), Positives = 109/264 (41%), Gaps = 44/264 (16%)

Query: 245  KIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNH 304
            +I N  +Q   + +    LE+  N L  E  D  VDL+  + ++ + +      ++ +  
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN-LEKKQRKFDQLLA 1465

Query: 305  RLSSIIDDSVCEQDGIKSDGTMKMSTDIT-----DSTLGSFEALGGETSKGVLEVSDLIA 359
               +I      E+D  +++   K +  ++     +  L + E L         E+ DL++
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525

Query: 360  Y-------VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSA------ 406
                    V +L  +KR LE +  + K  LE LE+   Q +ED  +LRL+V         
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATED-AKLRLEVNMQALKGQF 1583

Query: 407  --------HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL------- 451
                     Q   +   L+ +L E +  +    +Q+++  A  K+LE + + L       
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643

Query: 452  -------ILKIRILQEEMSDTYQR 468
                   I ++R LQ +M D +QR
Sbjct: 1644 IKGREEAIKQLRKLQAQMKD-FQR 1666



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 10/105 (9%)

Query: 343  LGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQ 402
            L G+ S    +++DL A +A+L     K EEE          L+   ++L ++  +    
Sbjct: 1067 LEGDASDFHEQIADLQAQIAELKMQLAKKEEE----------LQAALARLDDEIAQKNNA 1116

Query: 403  VKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
            +K   +     + L+E+L+  + + N +E+QK  +  + + L+TE
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1161



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 20/100 (20%), Positives = 49/100 (49%)

Query: 364  LHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEEL 423
            LH  + +LE+E  +  LA    ++    L +   +    +K   +AI +   L+ ++++ 
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 1664

Query: 424  KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMS 463
            +  +  +   +  I A +K+ E + ++L   +  LQE+++
Sbjct: 1665 QRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1704



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 341  EALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELR 400
            E  G   SK    ++ L A +A L   + ++E+E  + + A ++L++ + +L E   ++ 
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQL---EEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 1866

Query: 401  LQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
             + K A Q   +       +++LK  +  +EE+   I A  ++L+ E
Sbjct: 1867 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 13/101 (12%)

Query: 369  RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM- 427
            R+LEEE N  +  L+   E    L    + L +Q+  + + +       E LEE K    
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405

Query: 428  ----NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
                N +++ +    A  K  +T+NR        LQ+E+ D
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNR--------LQQELDD 1438



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 27/207 (13%)

Query: 263  LEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKS 322
            LE+L   L+ +  D H  +   QA + +         E +   L+ + D+   + + +K 
Sbjct: 1060 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1119

Query: 323  DGTMKMSTDITDSTLGSFEA-----------LGGETSKGVLEVSDLIAYVADLHFNKRKL 371
               ++         L S  A           LG E      E+ D +   A     + K 
Sbjct: 1120 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1179

Query: 372  EEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASE 431
            E+E    K AL+  EET S  ++   E+R +   A +       L E+LE+ K +     
Sbjct: 1180 EQEVTVLKKALD--EETRSHEAQ-VQEMRQKHAQAVEE------LTEQLEQFKRA----- 1225

Query: 432  EQKSMIVAQSKQLETENRALILKIRIL 458
              K+ +    + LE EN  L  ++R+L
Sbjct: 1226 --KANLDKNKQTLEKENADLAGELRVL 1250



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 10/118 (8%)

Query: 354  VSDLIAYVADLHFNKRKLEEENNKFKLALETLE-------ETNSQLSEDCTELRLQVKSA 406
            +SDL   +A+     + L +  NK +  +  LE       ++  +L +   +L       
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074

Query: 407  HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            H+ I     L+ ++ ELK+ +   EE+    +A+      +    + KIR L+  +SD
Sbjct: 1075 HEQIAD---LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1129


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 11/129 (8%)

Query: 369 RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKS-------AHQAIMRTNLLKEELE 421
           +K +E   K +  L+ LE+ +SQL+E+   L+ Q+++       A +  +R    K+ELE
Sbjct: 862 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921

Query: 422 ELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSDTYQRIVPNQF-RIEIEG 480
           E+   M A  E++     + +QL+ E + +  ++  L+E++ +        Q  ++  E 
Sbjct: 922 EILHEMEARLEEEE---DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978

Query: 481 RLKALHHEI 489
           ++K L  EI
Sbjct: 979 KIKKLEDEI 987



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 5/136 (3%)

Query: 316  EQDGIKSDGTMKMSTDITDSTLGSFEALGGETSKGVLEVSDLIAYVADLHFNKRKLEEEN 375
            +Q  + +    K+  D+ D  L +  A+ G   + + ++  L A + D            
Sbjct: 1610 KQRALAAAAKKKLEGDLKDLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASR 1668

Query: 376  NKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEEL-EELKLSM---NASE 431
            ++     +  E+    L  D  +L+  + +A +A  + +L KEEL EEL  S+   NA +
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728

Query: 432  EQKSMIVAQSKQLETE 447
            ++K  + A+  QLE E
Sbjct: 1729 DEKRRLEARIAQLEEE 1744



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 17/139 (12%)

Query: 368  KRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM 427
            K++LEE  ++ +  LE  E+   QL  +  ++  Q+            L+E+LEE + + 
Sbjct: 917  KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD----------LEEQLEEEEAAR 966

Query: 428  NASEEQKSMIVAQSKQLETE-------NRALILKIRILQEEMSDTYQRIVPNQFRIEIEG 480
               + +K    A+ K+LE E       N  L  + ++L+E +SD    +   + + +   
Sbjct: 967  QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026

Query: 481  RLKALHHEIALQLLTYIRK 499
            +LK  H  +  +L   ++K
Sbjct: 1027 KLKNKHESMISELEVRLKK 1045



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 58/264 (21%), Positives = 109/264 (41%), Gaps = 44/264 (16%)

Query: 245  KIINFLRQTTSQNSEDSGLEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNH 304
            +I N  +Q   + +    LE+  N L  E  D  VDL+  + ++ + +      ++ +  
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN-LEKKQRKFDQLLA 1458

Query: 305  RLSSIIDDSVCEQDGIKSDGTMKMSTDIT-----DSTLGSFEALGGETSKGVLEVSDLIA 359
               +I      E+D  +++   K +  ++     +  L + E L         E+ DL++
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518

Query: 360  Y-------VADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSA------ 406
                    V +L  +KR LE +  + K  LE LE+   Q +ED  +LRL+V         
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATED-AKLRLEVNMQALKGQF 1576

Query: 407  --------HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRAL------- 451
                     Q   +   L+ +L E +  +    +Q+++  A  K+LE + + L       
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636

Query: 452  -------ILKIRILQEEMSDTYQR 468
                   I ++R LQ +M D +QR
Sbjct: 1637 IKGREEAIKQLRKLQAQMKD-FQR 1659



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 10/105 (9%)

Query: 343  LGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQ 402
            L G+ S    +++DL A +A+L     K EEE          L+   ++L ++  +    
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEE----------LQAALARLDDEIAQKNNA 1109

Query: 403  VKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
            +K   +     + L+E+L+  + + N +E+QK  +  + + L+TE
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 20/100 (20%), Positives = 49/100 (49%)

Query: 364  LHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEEL 423
            LH  + +LE+E  +  LA    ++    L +   +    +K   +AI +   L+ ++++ 
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 1657

Query: 424  KLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMS 463
            +  +  +   +  I A +K+ E + ++L   +  LQE+++
Sbjct: 1658 QRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1697



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 341  EALGGETSKGVLEVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELR 400
            E  G   SK    ++ L A +A L   + ++E+E  + + A ++L++ + +L E   ++ 
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQL---EEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 1859

Query: 401  LQVKSAHQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETE 447
             + K A Q   +       +++LK  +  +EE+   I A  ++L+ E
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 13/101 (12%)

Query: 369  RKLEEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSM- 427
            R+LEEE N  +  L+   E    L    + L +Q+  + + +       E LEE K    
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398

Query: 428  ----NASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
                N +++ +    A  K  +T+NR        LQ+E+ D
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNR--------LQQELDD 1431



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 27/207 (13%)

Query: 263  LEQLWNMLDPEKRDPHVDLETFQAMMKDWMAYCGNTWEGVNHRLSSIIDDSVCEQDGIKS 322
            LE+L   L+ +  D H  +   QA + +         E +   L+ + D+   + + +K 
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK 1112

Query: 323  DGTMKMSTDITDSTLGSFEA-----------LGGETSKGVLEVSDLIAYVADLHFNKRKL 371
               ++         L S  A           LG E      E+ D +   A     + K 
Sbjct: 1113 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1172

Query: 372  EEENNKFKLALETLEETNSQLSEDCTELRLQVKSAHQAIMRTNLLKEELEELKLSMNASE 431
            E+E    K AL+  EET S  ++   E+R +   A +       L E+LE+ K +     
Sbjct: 1173 EQEVTVLKKALD--EETRSHEAQ-VQEMRQKHAQAVEE------LTEQLEQFKRA----- 1218

Query: 432  EQKSMIVAQSKQLETENRALILKIRIL 458
              K+ +    + LE EN  L  ++R+L
Sbjct: 1219 --KANLDKNKQTLEKENADLAGELRVL 1243



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 10/118 (8%)

Query: 354  VSDLIAYVADLHFNKRKLEEENNKFKLALETLE-------ETNSQLSEDCTELRLQVKSA 406
            +SDL   +A+     + L +  NK +  +  LE       ++  +L +   +L       
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067

Query: 407  HQAIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQLETENRALILKIRILQEEMSD 464
            H+ I     L+ ++ ELK+ +   EE+    +A+      +    + KIR L+  +SD
Sbjct: 1068 HEQIAD---LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,054,577
Number of Sequences: 37866
Number of extensions: 793650
Number of successful extensions: 4231
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 337
Number of HSP's that attempted gapping in prelim test: 3225
Number of HSP's gapped (non-prelim): 1268
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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