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Search of human proteins with 238231392
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
(2099 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 4169 0.0
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 2325 0.0
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 2054 0.0
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 588 e-167
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 545 e-154
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 515 e-145
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 515 e-145
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] 273 1e-72
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] 273 1e-72
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 74 2e-12
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 71 1e-11
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 67 1e-10
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 64 2e-09
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 58 9e-08
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 37 0.27
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 35 0.77
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 35 0.77
gi|156104862 ankyrin repeat domain 38 [Homo sapiens] 35 1.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 34 1.3
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 33 2.9
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 33 2.9
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 33 2.9
gi|52630429 nuclear factor, interleukin 3 regulated [Homo sapiens] 32 5.0
gi|45827731 scribble isoform a [Homo sapiens] 32 5.0
gi|7662454 vasohibin 1 [Homo sapiens] 32 6.5
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens] 32 6.5
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens] 32 6.5
gi|112421108 capicua homolog [Homo sapiens] 32 6.5
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ... 32 8.5
gi|122937211 KIAA0368 protein [Homo sapiens] 32 8.5
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 4169 bits (10811), Expect = 0.0
Identities = 2099/2099 (100%), Positives = 2099/2099 (100%)
Query: 1 MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVE 60
MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVE
Sbjct: 1 MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVE 60
Query: 61 PVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRD 120
PVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRD
Sbjct: 61 PVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRD 120
Query: 121 CVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPR 180
CVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPR
Sbjct: 121 CVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPR 180
Query: 181 HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFA 240
HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFA
Sbjct: 181 HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFA 240
Query: 241 LYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKIS 300
LYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKIS
Sbjct: 241 LYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKIS 300
Query: 301 ENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGD 360
ENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGD
Sbjct: 301 ENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGD 360
Query: 361 CAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLERE 420
CAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLERE
Sbjct: 361 CAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLERE 420
Query: 421 VTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLS 480
VTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLS
Sbjct: 421 VTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLS 480
Query: 481 DEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRP 540
DEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRP
Sbjct: 481 DEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRP 540
Query: 541 HKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPV 600
HKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPV
Sbjct: 541 HKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPV 600
Query: 601 IFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGA 660
IFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGA
Sbjct: 601 IFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGA 660
Query: 661 SVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKG 720
SVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKG
Sbjct: 661 SVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKG 720
Query: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL
Sbjct: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
Query: 781 NSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKD 840
NSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKD
Sbjct: 781 NSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKD 840
Query: 841 QHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARV 900
QHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARV
Sbjct: 841 QHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARV 900
Query: 901 MSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHF 960
MSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHF
Sbjct: 901 MSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHF 960
Query: 961 HEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDI 1020
HEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDI
Sbjct: 961 HEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDI 1020
Query: 1021 TTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLS 1080
TTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLS
Sbjct: 1021 TTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLS 1080
Query: 1081 AKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQD 1140
AKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQD
Sbjct: 1081 AKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQD 1140
Query: 1141 QKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDP 1200
QKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDP
Sbjct: 1141 QKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDP 1200
Query: 1201 RCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVA 1260
RCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVA
Sbjct: 1201 RCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVA 1260
Query: 1261 LAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLP 1320
LAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLP
Sbjct: 1261 LAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLP 1320
Query: 1321 STQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMR 1380
STQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMR
Sbjct: 1321 STQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMR 1380
Query: 1381 RRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDM 1440
RRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDM
Sbjct: 1381 RRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDM 1440
Query: 1441 QENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEE 1500
QENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEE
Sbjct: 1441 QENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEE 1500
Query: 1501 VEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVG 1560
VEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVG
Sbjct: 1501 VEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVG 1560
Query: 1561 RAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDP 1620
RAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDP
Sbjct: 1561 RAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDP 1620
Query: 1621 EMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLE 1680
EMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLE
Sbjct: 1621 EMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLE 1680
Query: 1681 DHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFS 1740
DHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFS
Sbjct: 1681 DHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFS 1740
Query: 1741 TGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFF 1800
TGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFF
Sbjct: 1741 TGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFF 1800
Query: 1801 GSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNK 1860
GSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNK
Sbjct: 1801 GSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNK 1860
Query: 1861 AYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLT 1920
AYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLT
Sbjct: 1861 AYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLT 1920
Query: 1921 TMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGS 1980
TMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGS
Sbjct: 1921 TMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGS 1980
Query: 1981 VGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQR 2040
VGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQR
Sbjct: 1981 VGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQR 2040
Query: 2041 EYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS 2099
EYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS
Sbjct: 2041 EYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS 2099
>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
Length = 2109
Score = 2325 bits (6025), Expect = 0.0
Identities = 1208/2133 (56%), Positives = 1570/2133 (73%), Gaps = 73/2133 (3%)
Query: 7 AERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSL-------------QLP 53
AERRAFA KI+R +AE+RKQ + GQY SG P L
Sbjct: 2 AERRAFAQKISRTVAAEVRKQIS-----GQY-------SGSPQLLKNLNIVGNISHHTTV 49
Query: 54 QFYDPVEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVE 113
+ V+PVD E L+TH ++D ++L +F DD++VV++P++CRTL ++PEE E
Sbjct: 50 PLTEAVDPVDLEDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVPEES-E 108
Query: 114 LDPHVRDCVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLEC--S 171
+DPHVRDC+++Y +W IV RK +K+ K LPKQ FES+ S
Sbjct: 109 MDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNS 168
Query: 172 EPAAQAGPRHLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARR 231
Q + ++ D + +G FDL++ PD L NLL + E+ ++QN++ R+
Sbjct: 169 YQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRK 228
Query: 232 TNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALY 291
+NR ELFAL+PS DEE+ +E VP+ PKEH G R+LVK L+LKFEIEIEP+FAS+ALY
Sbjct: 229 SNRHKELFALHPSPDEEEPIERLSVPDIPKEHFGQRLLVKCLSLKFEIEIEPIFASLALY 288
Query: 292 DVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEK 351
DVKE+KKISENF+ DLNS+Q KG LR H P A ++ ARSA+FS+TYPS D++LV+K+EK
Sbjct: 289 DVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEK 348
Query: 352 VLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSF 411
VLQQG+IG+CAEPY + KE+D K+KEK+EKLK QA+ FCQRLGKYRMPFAW I L +
Sbjct: 349 VLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNI 408
Query: 412 FN-VSTLEREVTDVDSVVG--RSSVGERRTLA-QSRRLSERALSLEENGVGSNFKTSTLS 467
+ +LER+ T+V+ G + S ERR + RR ER S ++ ++F+ +TL+
Sbjct: 409 VSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLT 468
Query: 468 VSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEM 527
V++FFKQEGDRLSDEDL+KFLAD +R SS+ RR++ I L+++IS APE + CLTPE+
Sbjct: 469 VTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPEL 528
Query: 528 LPVKPFPENRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQ 587
L VK +P++R RP +EILEFP R+VYVP+T YRNLLY+YPQ LNF N+ SARNIT+K+Q
Sbjct: 529 LQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQ 588
Query: 588 FMCGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLF 647
FM GED SNAMPVIFGKSS EF +E YTAV YHN+SPDF+EE+K+KLPA LT +HHLLF
Sbjct: 589 FMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLF 648
Query: 648 TFYHISCQQKQGASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPL 707
TFYH+SCQQKQ +ET +GY+W+P+L N RL+TG +CLPV+LEK P YS+ S E VPL
Sbjct: 649 TFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPE-VPL 707
Query: 708 QNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEM 767
P +KW + HKGVFN+EV AVSS+HTQD +L+KFF L ++L+ + FP+R+ D +I E
Sbjct: 708 --PGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHL-FPVRIGDMRIMEN 764
Query: 768 ALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAI 827
LE+ELK SI LNSS+LEP+V FLHL+LDKL L ++P VIAGQ N Q +FE++ +I
Sbjct: 765 NLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQASFEAMASI 824
Query: 828 ANSLHNSKDLSKDQHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTS 887
N LH + + + DQHGRN LLASY+HYVFRLP + G P L Y T R++
Sbjct: 825 INRLHKNLEGNHDQHGRNSLLASYIHYVFRLPNTYPNSSSPG-PGGLGGSVHYATMARSA 883
Query: 888 AAAVSSKLLQARVMSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPS 947
S L ++R +S+SNPD++GT ++ D+EV++I+ SK DR+C+RMS + SS +
Sbjct: 884 VRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMDRSCNRMSSHTETSSFLQT 943
Query: 948 SPAAPRPASKKHFHEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSF 1007
R +KK FHEELALQ VV +G VRE+ + AWFFFEL+VKSM H++ DK ++
Sbjct: 944 LTG--RLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLEAP 1001
Query: 1008 RRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGF 1067
R++RF +RFMDDI +V+ + S+I + QK+ E E++N SLAFFL DLLS+MDRGF
Sbjct: 1002 RKSRFPERFMDDIAALVSTIASDIVSRF---QKDTEMVERLNTSLAFFLNDLLSVMDRGF 1058
Query: 1068 VFNLIRHYCSQLSAKLSNLPT---LISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPC 1124
VF+LI+ Q+S+KL +LP L+S+RL+FLRI+CSHEHY+ LNL + T P SP
Sbjct: 1059 VFSLIKSCYKQVSSKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLP-CSLLTPPASPS 1117
Query: 1125 PSISS---QNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKV 1181
PS+SS Q+S ++ QDQKIA+MF+L+ +RQQH+L GL+ TELA LD + EG+ +
Sbjct: 1118 PSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGL 1177
Query: 1182 QRKAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYR 1241
+K ++ +H+LLSSHD DPR P++K ++A LYLPL+GII++ +PQL DFT +R R
Sbjct: 1178 HKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTETHNQRGR 1237
Query: 1242 T---SGSDEEQEGAGAINQNVALAIAGNNFNLKT--SGIVLSSLPYKQYNMLNADTTRNL 1296
+ D E E I+Q VA+AIAG + T +L+S +Q+ +A+++R+L
Sbjct: 1238 PICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSL 1297
Query: 1297 MICFLWIMKNADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQK 1356
+IC LW++KNAD+++++KW DL QLNR+LDLL++CV CFEYKGK+ +++++ +K
Sbjct: 1298 LICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKK 1357
Query: 1357 SRDVKARLEEALLRGEGARGEMMRR---------------RAPGNDRFPGLNENLRWKKE 1401
S+D++A+LEEA+L GAR EM+RR R+P F G ENLRW+K+
Sbjct: 1358 SKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTIASPPERSPSGSAF-GSQENLRWRKD 1416
Query: 1402 QTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENIIQASSALDCKDSLLGGV 1461
THWRQ EKLDK++AE++ EALI GNLATEA+LIILD E ++Q S + K+S+LGGV
Sbjct: 1417 MTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGV 1476
Query: 1462 LRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDV 1521
L+VL++S+ C+QS YL HCFAT RAL++KF +LLFEEE EQC DLC ++L HCSSS+
Sbjct: 1477 LKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSIGT 1536
Query: 1522 TRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYS 1581
RS A A+LYLLMR +F +NFARVKMQVTMSL+SLVG + +FNEE LRRSL+TIL Y+
Sbjct: 1537 IRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYA 1596
Query: 1582 EEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLR 1641
EED ++ T FP QV++L+ NL+ IL DTVKM+E QEDPEML+DLMYRIAK YQ SPDLR
Sbjct: 1597 EEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLR 1656
Query: 1642 LTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLE 1701
LTWLQNMA KH+++ + EAA CLVH+AALVAEYLSMLED YLPVG V+FQNISSNVLE
Sbjct: 1657 LTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLE 1716
Query: 1702 ESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEA 1761
ES VS+D +SPDE+G+C+G+YFTESGLVGLLEQAA FS G+YE VNEVYK++IPI EA
Sbjct: 1717 ESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEA 1776
Query: 1762 HREFRKLTLTHSKLQRAFDSIVNKD--HKRMFGTYFRVGFFGSKFGDLDEQEFVYKEPAI 1819
+R+ +KL+ H KLQ AF IV++ +RMFGTYFRVGF+G+KFGDLDEQEFVYKEPAI
Sbjct: 1777 NRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAI 1836
Query: 1820 TKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKD 1879
TKL EISHRLE FYG+ FG + VEVIKDS PVDK KLDPNKAYIQIT+VEPYFD YEMKD
Sbjct: 1837 TKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKD 1896
Query: 1880 RVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEE 1939
R+TYF+KN+NLRRFMY TPFTL+GR GELHEQ++R T+LTT HAFPYIKTR++V KEE
Sbjct: 1897 RITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEE 1956
Query: 1940 FVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAE 1999
+LTPIEVAIEDM+KKT +LA A +Q+P D KMLQMVLQGSVG TVNQGPLEVAQVFL+E
Sbjct: 1957 IILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSE 2016
Query: 2000 IPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRP 2059
IP+DPKL+RHHNKLRLCFK+F RC +A+ KNK LI DQ+EYQ+EL++NY++LKE L+P
Sbjct: 2017 IPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQP 2076
Query: 2060 MIERKIPELYKPIFRVESQKRDSFHRSSFRKCE 2092
+I RKIP+LYK + V RDSF R S RK +
Sbjct: 2077 LINRKIPQLYKAVLPVTCH-RDSFSRMSLRKMD 2108
>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
Length = 2047
Score = 2054 bits (5322), Expect = 0.0
Identities = 1094/2112 (51%), Positives = 1468/2112 (69%), Gaps = 89/2112 (4%)
Query: 4 LPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYH--RQSISTSGFPSLQLPQFYDPVEP 61
+ ++ERRAFA KINR +AE+RKQ + + G H R+ S+ G P ++ VEP
Sbjct: 1 MAASERRAFAHKINRTVAAEVRKQVSRERS-GSPHSSRRCSSSLGVPLTEV------VEP 53
Query: 62 VDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRDC 121
+DFE +L++ + ++L +F DDL+++ P+ECRT +P +P++ +LD VR
Sbjct: 54 LDFEDVLLSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDE-KLDAQVRAA 112
Query: 122 VQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETL--ECSEPAAQAGP 179
V+ YI +W+IV+R+ Q T ++++ K LP+Q FE + E S P
Sbjct: 113 VEMYIEDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDS 172
Query: 180 RHLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELF 239
R + + + + + FDLR+L D L +LL++ + ED +++NE RR +R L
Sbjct: 173 RRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALL 232
Query: 240 ALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKI 299
LYP+ DE++AVE PE P+EH G RILVK L+LKFEIEIEP+F +ALYDV+E+KKI
Sbjct: 233 TLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGILALYDVREKKKI 292
Query: 300 SENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIG 359
SENF+ DLNSD KG LRAH A S+ ARSA+FSVTYPS DI+LV+K+EKVLQQG+I
Sbjct: 293 SENFYFDLNSDSMKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDIS 352
Query: 360 DCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLER 419
+C EPY V+KE D K+KEK+EKL+L AE FC RLG+YRMPFAW + L++ VS+ +
Sbjct: 353 ECCEPYMVLKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANI--VSSAGQ 410
Query: 420 EVTDVDSVVGRSSVGERRTLAQSRRL---SERALSLEENGVGSNFKTSTLSVSSFFKQEG 476
D DS GERR RR +RA S ++ S F+ +TL+V++FFKQE
Sbjct: 411 LDRDSDSE------GERRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFFKQEA 464
Query: 477 DRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPEN 536
+RLSDEDLFKFLAD +R SSL RR++ + L+++IS APE + CL+PE+L +KP+P+
Sbjct: 465 ERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKPYPDP 524
Query: 537 RTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASN 596
R RP KEILEFP REVY PHT YRNLLYVYP LNF ++ S RN+ +++Q+M GED S
Sbjct: 525 RGRPTKEILEFPAREVYAPHTSYRNLLYVYPHSLNFSSRQGSVRNLAVRVQYMTGEDPSQ 584
Query: 597 AMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQ 656
A+PVIFGKSS EF +E +T V YHNKSP+FYEE K+ LPA +T NHHLLFTFYH+SCQ
Sbjct: 585 ALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQP 644
Query: 657 KQGASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAE 716
+ G ++ET +G++W+P+L + RL+TG +CLPV++++ PP+YS+ + + + P ++W +
Sbjct: 645 RPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPD---VALPGMRWVD 701
Query: 717 GHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLS 776
GHKGVF++E+ AVSSVH QD +L+KFFTL H LE + FP R+ D +SE +E EL+ S
Sbjct: 702 GHKGVFSVELTAVSSVHPQDPYLDKFFTLVHVLE-EGAFPFRLKDTVLSEGNVEQELRAS 760
Query: 777 IICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKD 836
+ L + EPLV F H VLDKL +L ++P +I+GQ N + AFE++ + + +H S +
Sbjct: 761 LAALRLASPEPLVAFSHHVLDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLE 820
Query: 837 LSKDQHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLL 896
++D G LA+YVHY FRLP + +P GAP + T R S S L
Sbjct: 821 AAQDARGHCPQLAAYVHYAFRLPGTEPSLP-DGAPPVTVQAA---TLARGSGRPASLYLA 876
Query: 897 QARVMSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPAS 956
+++ +SSSNPDLA + D+EV I++SK+
Sbjct: 877 RSKSISSSNPDLAVAPGSVDDEVSRILASKL----------------------------- 907
Query: 957 KKHFHEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRF 1016
HEELALQ VVS+ VRE + ++AWFFF+L+VKSMA H+ + D+ R+ RF RF
Sbjct: 908 ---LHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRFPGRF 964
Query: 1017 MDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYC 1076
+DDIT +V V E+ + + K+ E AE +N SLAFFL DLLSL+DRGFVF+L+R +
Sbjct: 965 LDDITALVGSVGLEV---ITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAHY 1021
Query: 1077 SQLSAKLSNLPT---LISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISS---Q 1130
Q++ +L + P L+++R+EF RILCSHEHY+ LNL + P SP PS+SS Q
Sbjct: 1022 KQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPL-SPPASPSPSVSSTTSQ 1080
Query: 1131 NSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIH 1190
+S+ S D K+ SMF+L+ +RQQHFL GLL TELA AL+ E EG + +KA+SA+H
Sbjct: 1081 SSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVH 1140
Query: 1191 SLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSG---SDE 1247
SLL HD DPR + VK ++A LYLPL+ I D LP+L DF +R R + SD
Sbjct: 1141 SLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLHDFAEGPGQRSRLASMLDSDT 1200
Query: 1248 EQEG--AGAINQNVALAIAGNNFNLKTSGIVLSSLPYKQYN--MLNADTTRNLMICFLWI 1303
E EG AG IN +VA+AIAG + + P L+A+++R L+ C LW+
Sbjct: 1201 EGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCALSAESSRTLLACVLWV 1260
Query: 1304 MKNADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKAR 1363
+KN + +L+++W DL QL R+LDLL++C+ FEYKGK++ +++++ +KS D+KAR
Sbjct: 1261 LKNTEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKAR 1320
Query: 1364 LEEALLRGEGARGEMMRRRAPGNDRFP-GLNENLRWKKEQTHWRQANEKLDKTKAELDQE 1422
LEEA+L GAR EM+RR +R P G EN+RW+K THW+Q ++++DKTK E++ E
Sbjct: 1321 LEEAILGTIGARQEMVRR---SRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHE 1377
Query: 1423 ALISGNLATEAHLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCF 1482
AL+ GNLATEA L++LD E I+Q + ++S+LG VL+V++ SL QS +L H
Sbjct: 1378 ALVEGNLATEASLVVLDTLEIIVQTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGL 1437
Query: 1483 ATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATS 1542
AT RAL++KF +LLFEE+ E C DLC ++L HC S + R+ A A+LYLLMR +F
Sbjct: 1438 ATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGH 1497
Query: 1543 NFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCN 1602
NFARVKMQVTMSL+SLVG +F+EEHLRRSL+TIL Y+EED ++ + F QV++L+ N
Sbjct: 1498 NFARVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFN 1557
Query: 1603 LNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAA 1662
L+ IL DTVKM+E QEDPEML+DLMYRIA+ YQ SPDLRLTWLQNMA KH + + EAA
Sbjct: 1558 LHMILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAA 1617
Query: 1663 MCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQY 1722
C+VHAAALVAEYL++LEDH +LPVG VSFQNISSNVLEES +S+D LSPDE+G C+G++
Sbjct: 1618 QCMVHAAALVAEYLALLEDHRHLPVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKH 1677
Query: 1723 FTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSI 1782
FTE GLVGLLEQAA F+ GGLYE VNEVYK +IPILEAHR+++KL H KLQ AF I
Sbjct: 1678 FTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKI 1737
Query: 1783 VNKDH--KRMFGTYFRVGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAE 1840
+++ +R+FGTYFRVGF+G+ FGDLDEQEFVYKEP+ITKL EISHRLE FY + FG +
Sbjct: 1738 MHQSSGWERVFGTYFRVGFYGAHFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDD 1797
Query: 1841 FVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFT 1900
VE+IKDS PVDK+KLD KAYIQIT+VEPYFD YE+KDRVTYF++N+ LR F++ TPFT
Sbjct: 1798 VVEIIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFT 1857
Query: 1901 LEGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLA 1960
+GR GEL EQ++R T+L+T HAFPYIKTRI V +EE VLTP+EVAIEDM+KKT +LA
Sbjct: 1858 PDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELA 1917
Query: 1961 VAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEF 2020
A Q+PPDAKMLQMVLQGSVG TVNQGPLEVAQVFLAEIP DPKL+RHHNKLRLCFK+F
Sbjct: 1918 FATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDF 1977
Query: 2021 IMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKR 2080
+C +A+ KNK LI DQ+EY +EL++NY +L+E L+P++ +++P+L P R
Sbjct: 1978 CKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLPQLMAP---TPPGLR 2034
Query: 2081 DSFHRSSFRKCE 2092
+S +R+SFRK +
Sbjct: 2035 NSLNRASFRKAD 2046
>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
Length = 2073
Score = 588 bits (1517), Expect = e-167
Identities = 392/1173 (33%), Positives = 601/1173 (51%), Gaps = 112/1173 (9%)
Query: 946 PSSPAAPRPASKKHFHEELALQMVVSTGMVRE-----TVFKYAWFFFELLVKSMAQHVHN 1000
P P+AP+ + HE LA M+ + + KY+WFFFE++ KSMA ++
Sbjct: 922 PEKPSAPQA---QLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLE 978
Query: 1001 MDKRDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLL 1060
+K R RF + + + +++ + + ++ + +++ +N SLA FL L
Sbjct: 979 ENKIKLPRGQRFPETYHHVLHSLLLAIIPHVT---IRYAEIPDESRNVNYSLASFLKRCL 1035
Query: 1061 SLMDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAP 1120
+LMDRGF+FNLI Y S S K + L + EFL+ +C+HEHY+ LNL A
Sbjct: 1036 TLMDRGFIFNLINDYISGFSPK--DPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAK--- 1090
Query: 1121 TSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISK 1180
P + S+ + L+ EY + HFL GLL E + AL E
Sbjct: 1091 ----PKLQRVQDSNLE----------YSLSDEYCKHHFLVGLLLRETSIALQDNYE---- 1132
Query: 1181 VQRKAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL----------- 1229
++ A+S I +LL H D R + KIA LYLP VG++L+ + +L
Sbjct: 1133 IRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAA 1192
Query: 1230 -----------CDFTVADTRRYRTSGSD--------------EEQEGAGAINQNVALAIA 1264
C FT R ++ D E+ G+
Sbjct: 1193 MPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQ 1252
Query: 1265 GNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKN-ADQSLIRKWIADLPSTQ 1323
GN SS+ QYN L+ R+L++C+L+I+K ++ +L+ W P
Sbjct: 1253 GNTGENTRQSSTRSSV--SQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQEL 1310
Query: 1324 LNRILDLLFICVLCFEYKGKQSSDKVSTQVLQK--SRDVKARLEEALLRGEGARGEMMRR 1381
+N IL LL +C+ F Y GK++ +V L K D K++ AL G ++
Sbjct: 1311 IN-ILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQH 1369
Query: 1382 RAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQ 1441
+ F N T+A++ +AL+ GN ATE L +LD
Sbjct: 1370 LSSLESSFT-----------------LNHSSTTTEADIFHQALLEGNTATEVSLTVLDTI 1412
Query: 1442 ENIIQASSAL----DCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLF 1497
Q D + L+ V + + L QS L H FA+LRA I+KF F
Sbjct: 1413 SFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFF 1472
Query: 1498 EEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSN--FARVKMQVTMSL 1555
+ V C C++VL C+S + TR++A A LYLLMR +F T F R +Q+ +++
Sbjct: 1473 KGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAV 1532
Query: 1556 ASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMRE 1615
+ L+ + SL I ++ D M+ T FP +V++L + ++L T +M+E
Sbjct: 1533 SQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKE 1592
Query: 1616 FQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEY 1675
++DPEML+DL Y +AKSY ++P+LR TWL +MA+ H K ++EAAMC VH AALVAE+
Sbjct: 1593 HEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEF 1652
Query: 1676 LSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQA 1735
L + P G +F+ I+ N+ EE + ED D +++E L+ LLEQ
Sbjct: 1653 LHRKK---LFPNGCSAFKKITPNIDEEGAMKEDAGMMDV-------HYSEEVLLELLEQC 1702
Query: 1736 AELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDH--KRMFGT 1793
+ YE ++E+ KL++PI E REF KLT + L A+ I+ H KR+ GT
Sbjct: 1703 VDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGT 1762
Query: 1794 YFRVGFFG-SKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVD 1852
+FRV F+G S F + D +E++YKEP +T L EIS RL YG+ FG E V++I+DS V+
Sbjct: 1763 FFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVN 1822
Query: 1853 KTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQ 1912
+LDP A+IQ+T+V+PYFD+ E+ +R T FE+N N+ RF++ P+TL G+ +G + EQ
Sbjct: 1823 AKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQ 1882
Query: 1913 YRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKM 1972
+R T+LTT ++FPY+K RI + +++ L PI+VA +++K KT +L + D
Sbjct: 1883 CKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQ 1942
Query: 1973 LQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNK 2032
LQ+ LQG V VN GPL A+ FL + A + ++L+ F++FI C A+E N+
Sbjct: 1943 LQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNE 2002
Query: 2033 RLITADQREYQQELKKNYNKLKENLRPMIERKI 2065
RLI DQ EY + LK N+ + + L +I +I
Sbjct: 2003 RLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQI 2035
Score = 286 bits (733), Expect = 1e-76
Identities = 220/699 (31%), Positives = 337/699 (48%), Gaps = 135/699 (19%)
Query: 223 EKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEI--- 279
E+ N+ +R RQ LF+ V D I P + +E R LV L F I
Sbjct: 323 EQLNKLSRGDGRQ-NLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQ 381
Query: 280 ----------EIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVA----- 324
+EP F ++AL+DVK KIS +FH DLN + L + +A
Sbjct: 382 IGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSP 441
Query: 325 ------------ASSQAR---SAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIK 369
A SQ R +FSVT P +I+LV +IEKVLQ G I CAEPY IK
Sbjct: 442 KGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQ-GNITHCAEPY--IK 498
Query: 370 ESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVG 429
SD K+ +K+ + A+ C RLG+YRMPFAWA +
Sbjct: 499 NSDPVKTAQKVHRT---AKQVCSRLGQYRMPFAWAARPI--------------------- 534
Query: 430 RSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLA 489
+ SL+ +G S +KQ+ +LS ED+ K L+
Sbjct: 535 ---------------FKDTQGSLDLDG----------RFSPLYKQDSSKLSSEDILKLLS 569
Query: 490 DYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRPHKEILEF-P 548
+YK+ + ++ IPG L + + P ++ C+T +P+KPF +N E+ EF P
Sbjct: 570 EYKKPEKTKLQI--IPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVP 627
Query: 549 TREVYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFMCGEDA-SNAMPVIFGK 604
Y P T+Y+N LYVYP +L + ++ A ARNI + ++F +++ ++A+ I+GK
Sbjct: 628 EMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGK 687
Query: 605 SSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ------QKQ 658
+G F Y V++HN++P+FY+E+KI+LP L HHLLFTFYH+SC+ K+
Sbjct: 688 PAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKK 747
Query: 659 GASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNY-SMHSAEKVPLQNPPIKWAEG 717
+VET +G++W+P+L + R+ T LPV+ LPP Y +++ AE N IKW +G
Sbjct: 748 QDTVETPVGFAWVPLLKDGRIITFEQQLPVS-ANLPPGYLNLNDAESRRQCNVDIKWVDG 806
Query: 718 HKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSI 777
K + I+ S+++TQD H+ KFF C ++S + EL +
Sbjct: 807 AKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQS-------------GSKEVPGELIKYL 853
Query: 778 ICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDL 837
CL++ ++ ++ FL ++L +LF++ + E V I ++ +
Sbjct: 854 KCLHAMEIQVMIQFLPVILMQLFRV-------------LTNMTHEDDVPINCTMVLLHIV 900
Query: 838 SK-DQHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALL 875
SK + G + L S++ Y FR PE K AP A L
Sbjct: 901 SKCHEEGLDSYLRSFIKYSFR-PE------KPSAPQAQL 932
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/119 (28%), Positives = 62/119 (52%), Gaps = 7/119 (5%)
Query: 22 AEIRKQFTL---PPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVQ 78
AE+RK FT P RQS+S + S+ L + VEP+D+E ++ +
Sbjct: 2 AEVRK-FTKRLSKPGTAAELRQSVSEAVRGSVVLEKA-KVVEPLDYENVIAQRKTQIYSD 59
Query: 79 LAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVE--LDPHVRDCVQTYIREWLIVNRK 135
++L F +D+ + ++ RT+Q ++PE+ + V++C++TY +W +VN K
Sbjct: 60 PLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYK 118
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 545 bits (1405), Expect = e-154
Identities = 373/1231 (30%), Positives = 611/1231 (49%), Gaps = 155/1231 (12%)
Query: 953 RPASKKHFHEELALQMVVSTGMVRET-------VFKYAWFFFELLVKSMAQHVHNMDKRD 1005
R ++ HEELA + TG+++ V K++WFFF +++KSMAQH+ + +K
Sbjct: 956 RACKERTVHEELAKNV---TGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQ 1012
Query: 1006 SFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDR 1065
R RF + + +++ +V V++ + + K + E+ + N S+A FL + MDR
Sbjct: 1013 LPRPQRFPESYQNELDNLVMVLSDHV---IWKYKDALEETRRANHSVARFLKRCFTFMDR 1069
Query: 1066 GFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTA-PTSPC 1124
G+VF ++ +Y S S+ +L TL + +FL+ +C HEH++ L L +A+ P +P
Sbjct: 1070 GYVFKMVNNYISMFSS--GDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPS 1127
Query: 1125 PSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRK 1184
S ++S + +T+E+ ++HFL G+L E+ AL + + V+
Sbjct: 1128 ESTQELHASDMPEYS---------VTNEFCRKHFLIGILLREVGFALQEDQD----VRHL 1174
Query: 1185 AVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQ-----LCDFTVADTRR 1239
A++ + +L++ H D R +P + +IA+LY+PL G++LD +P+ L FTV + +
Sbjct: 1175 ALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQ 1234
Query: 1240 YRTSGSDEEQEGAGAINQNVAL----------------------AIAGNNFNLKTSGIVL 1277
GS ++ G A+ +IA + N S L
Sbjct: 1235 ----GSRDDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASL 1290
Query: 1278 SSLPYK----------------------------QYNMLNADTTRNLMICFLWIMKNADQ 1309
+SL +++ L+ TR+L++CFL IMK
Sbjct: 1291 ASLDSNPSTNEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISY 1350
Query: 1310 SLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALL 1369
+ + PS +++ +L +C+ F Y GK++ + ++ + V++ L
Sbjct: 1351 ETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRN---IIRKIAAAFKFVQSTQNNGTL 1407
Query: 1370 RGE-------GARGEMMRRRAPGNDRFPGLNENL---RWKKEQTHWRQANEKLDKTKAEL 1419
+G G + M + ++ L R K ++ + + LD T
Sbjct: 1408 KGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQTLPIIRGKNALSNPKLL-QMLDNTMTSN 1466
Query: 1420 DQEALI------SGNLATEAHLIILDMQENIIQASSA----LDCKDSLLGGVLRVLVNSL 1469
E I N+ATE L ILD+ Q DC++SL+ V +
Sbjct: 1467 SNEIDIVHHVDTEANIATEVCLTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFF 1526
Query: 1470 NCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACAT 1529
+QS T L H FA+LR + KF F+ + C C++VL C+ T+++A A
Sbjct: 1527 QVNQSATALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASAL 1586
Query: 1530 LYLLMR--FSFGATSNFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAM 1587
LY MR F F + R +Q+ +++ L+ A + SL ++ D M
Sbjct: 1587 LYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIADA-GIGGSRFQHSLAITNNFANGDKQM 1645
Query: 1588 QMTPFPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQN 1647
+ + FP +V++L + ++L T +M+E ++DPEML+DL Y +A SY ++P+LR TWL++
Sbjct: 1646 KNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLES 1705
Query: 1648 MAEKHTKKKCYTEAAMCLVHAAALVAEYL--------------SMLEDHSY--------- 1684
MA+ H + +EAAMC +H AAL+AEYL S+L + ++
Sbjct: 1706 MAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLT 1765
Query: 1685 -------LPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAE 1737
+G +F +I+ N+ EE + ED+ D + E+ LV L E
Sbjct: 1766 TPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTP-------YNENILVEQLYMCVE 1818
Query: 1738 LFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSI--VNKDHKRMFGTYF 1795
YE + +V K +I + E R+F+KL+ + + R++ + V KR+FG Y+
Sbjct: 1819 FLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYY 1878
Query: 1796 RVGFFGSKFGDLDE-QEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKT 1854
RV F+G F + +E +E++YKEP +T L EIS RL Y FGA+ V++I+DS V+
Sbjct: 1879 RVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPK 1938
Query: 1855 KLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYR 1914
LDP AYIQ+T+V P+F+E E++DR T FE + N+ RF++ TPFTL G+ G + EQ +
Sbjct: 1939 DLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCK 1998
Query: 1915 RNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQ 1974
R T+LTT H FPY+K RI VI + L PIEVAI++M KK +L E D LQ
Sbjct: 1999 RRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQ 2058
Query: 1975 MVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRL 2034
+ LQGSV VN GP+ A+ FL E A L+ F++F CG+A++ N+RL
Sbjct: 2059 LKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERL 2118
Query: 2035 ITADQREYQQELKKNYNKLKENLRPMIERKI 2065
I DQ EYQ+EL+ +Y + L ++ +I
Sbjct: 2119 IKEDQLEYQEELRSHYKDMLSELSTVMNEQI 2149
Score = 285 bits (730), Expect = 3e-76
Identities = 214/696 (30%), Positives = 338/696 (48%), Gaps = 137/696 (19%)
Query: 182 LNVLCDVSGKGPVTA------CDFDLRSLQPDKRLENLLQQVSAE------DFEK---QN 226
LN + +S +GP+ D L SL E ++ + DF K +
Sbjct: 285 LNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTET 344
Query: 227 EEARRTNRQAE---LFALYPSVD-----EEDAVEIRPVPECPKEHLGNRILVKLLTLKFE 278
E+ +T R E LF+L P +D ++D +E V + +E RI++ L
Sbjct: 345 EDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSN 404
Query: 279 IE-------------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFL--------- 316
++ IEP F S+ALYD+++ +KIS +FH DLN + L
Sbjct: 405 LQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALEN 464
Query: 317 ---------RAHTPSVAASSQA-----RSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCA 362
++ P + + + AVFSV+ P S+I LV KIEKVL G I A
Sbjct: 465 GNIDTITPRQSEEPHIKGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLM-GNIASGA 523
Query: 363 EPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVT 422
EPY IK D K +KI K Q FC +LGKYRMPFAWA S+ N ++R+
Sbjct: 524 EPY--IKNPDSNKYAQKILKSNRQ---FCSKLGKYRMPFAWAVRSVFKD-NQGNVDRD-- 575
Query: 423 DVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDE 482
S F S F+QE ++S E
Sbjct: 576 ------------------------------------SRF-------SPLFRQESSKISTE 592
Query: 483 DLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPEN-RTRPH 541
DL K ++DY+R+ + + +++IPG L + + P C+T +PVKPF +T P
Sbjct: 593 DLVKLVSDYRRADRISK-MQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPT 651
Query: 542 KEILEF--PTREVYVPHTVYRNLLYVYPQRLNFVNKLA--SARNITIKIQFM-CGEDASN 596
E+ EF + + P+ VY+N +Y+YP+ L + ++ ARNIT+ I+F E+++
Sbjct: 652 VEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAK 711
Query: 597 AMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISC-- 654
+ I+GK GP F YTAV +H+++PDF +EVKI+LP +L HH+LF+FYH++C
Sbjct: 712 PLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDI 771
Query: 655 ----QQKQGASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNY-SMHSAEKVPLQN 709
K+ ++ET +GY+WLP++ ++++ + Y +P+A LPPNY S +
Sbjct: 772 NAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIA-TSLPPNYLSFQDSASGKHGG 830
Query: 710 PPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMAL 769
IKW +G K +F + VS+V+TQD H+ FF C E + +S+
Sbjct: 831 SDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKRE-----------KDMSQSPT 879
Query: 770 EHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQ 805
+ ++ LN ++ ++ FL ++L++LF++ VQ
Sbjct: 880 SNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQ 915
Score = 32.7 bits (73), Expect = 3.8
Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 6/109 (5%)
Query: 59 VEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPH- 117
+EP+D+E ++ + Q+L F DD + RTL ++PE+ +
Sbjct: 48 LEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENL 107
Query: 118 -VRDCVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFH-KTLPKQTFE 164
V++ + Y +W +VN K + + G + R ++ + LP +FE
Sbjct: 108 LVKEACKFYSSQWHVVNYKYE---QYSGDIRQLPRAEYKPEKLPSHSFE 153
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 515 bits (1327), Expect = e-145
Identities = 384/1230 (31%), Positives = 583/1230 (47%), Gaps = 196/1230 (15%)
Query: 950 AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003
A P AS+ K HEEL M + + + KY+WFFF++L+KSMAQH+ K
Sbjct: 920 AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 979
Query: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEK-MNISLAFFLYDLLSL 1062
R RF + + T+VN++ I ++N +A K N SLA F+ +
Sbjct: 980 VKLLRNQRFPASYHHAVETVVNMLMPHITQKF----RDNPEASKNANHSLAVFIKRCFTF 1035
Query: 1063 MDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTS 1122
MDRGFVF I +Y S + + TL + EFLR++C+HEHY+ LNL
Sbjct: 1036 MDRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL----------- 1082
Query: 1123 PCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQ 1182
P P +QD ++ + LT E+ + HFL GLL E+ AL + +V+
Sbjct: 1083 PMPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVR 1132
Query: 1183 RKAVSAIHSL------------------------------------LSSHDLDPRCVKPE 1206
A+S + +L ++ D+ P V
Sbjct: 1133 LIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAG 1192
Query: 1207 VKVKIAALYLPLVGIIL--------------DALPQLCDFTVADTRRYRTSGSDEEQEGA 1252
+ VK +L LP V ++ D L + T S +
Sbjct: 1193 MTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSR 1252
Query: 1253 GAINQNVALAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTR----------NLMICFLW 1302
G++ + GN+ + S S ++Q + L R +L++CFL+
Sbjct: 1253 GSLISTDS----GNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLY 1308
Query: 1303 IMKN-ADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVK 1361
I+K+ +D +L W +++L + +C+ F+Y GK+
Sbjct: 1309 ILKSMSDDALFTYW-NKASTSELMDFFTISEVCLHQFQYMGKRYI--------------- 1352
Query: 1362 ARLEEALLRGEGARGEMMRRRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQ 1421
AR MM R + L+ +L + H + A++
Sbjct: 1353 ------------ARTGMMHARL---QQLGSLDNSLTFNHSYGH----------SDADVLH 1387
Query: 1422 EALISGNLATEAHLIILDMQENIIQASSALDCKDS----LLGGVLRVLVNSLNCDQSTTY 1477
++L+ N+ATE L LD A D L+ V V + L QS T
Sbjct: 1388 QSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETA 1447
Query: 1478 LTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFS 1537
L + F LR+LI KF +E + C LC+++L C+S + R++A LY LMR +
Sbjct: 1448 LKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNN 1507
Query: 1538 FGATS--NFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQ 1595
F T +F R +QV +S++ L+ ++SL I + D ++ T F +
Sbjct: 1508 FDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSD 1567
Query: 1596 VEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKK 1655
V++L + ++L T +M+E + DPEML+DL Y +AKSY ++P+LR TWL +MA H K
Sbjct: 1568 VKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKN 1627
Query: 1656 KCYTEAAMCLVHAAALVAEYLSMLEDHSYLPV--------------------GSVSFQNI 1695
+EAAMC VH ALVAEYL+ E + P G +F+ I
Sbjct: 1628 GDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVI 1687
Query: 1696 SSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLV 1755
+ N+ EE+ + ED D +F E L+ LLEQ A+ YE + ++YKL+
Sbjct: 1688 TPNIDEEASMMEDVGMQDV-------HFNEDVLMELLEQCADGLWKAERYELIADIYKLI 1740
Query: 1756 IPILEAHREFRKLTLTHSKLQRAFDSIVNKDH--KRMFGTYFRVGFFGSK---------- 1803
IPI E R+F +L + L RA+ + H +R+ GTYFRV FFG
Sbjct: 1741 IPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSET 1800
Query: 1804 -----FGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDP 1858
F D D +E++YKEP +T L EIS RL Y FG+E V++I+DS V+ LD
Sbjct: 1801 DVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDS 1860
Query: 1859 NKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTV 1918
AYIQ+T V P+FDE E+++R T FE++ N+RRFM+ PFT G+ +G + EQ +R T+
Sbjct: 1861 KYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTI 1920
Query: 1919 LTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQ 1978
LT +H FPY+K RI V+ + L PIEVAI++M KK +L + D LQ+ LQ
Sbjct: 1921 LTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQ 1980
Query: 1979 GSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRL---CFKEFIMRCGEAVEKNKRLI 2035
GSV VN GPL A+ FL + + K Y NK++L F++F+ CG+A+ N+RLI
Sbjct: 1981 GSVSVQVNAGPLAYARAFLDD--TNTKRY-PDNKVKLLKEVFRQFVEACGQALAVNERLI 2037
Query: 2036 TADQREYQQELKKNYNKLKENLRPMIERKI 2065
DQ EYQ+E+K NY ++ + L ++ ++
Sbjct: 2038 KEDQLEYQEEMKANYREMAKELSEIMHEQL 2067
Score = 273 bits (698), Expect = 1e-72
Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)
Query: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280
++ E ++ + +LF L P + D P + +E G RILVK L F ++
Sbjct: 323 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 382
Query: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323
+EP F +++L+D+K +KIS +FH DLN + L +P++
Sbjct: 383 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 442
Query: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373
AA + +FSVT P DI+LV +IEKVLQ G I CAEPY +K SD
Sbjct: 443 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 499
Query: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433
K +K+ K QA CQRLG+YRMPFAWA
Sbjct: 500 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 528
Query: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493
RTL + + +L++N S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 529 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 570
Query: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551
+ + + I G L + I + +P K F ++T E+ EF P
Sbjct: 571 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 629
Query: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607
+ P+T+Y N LYVYP+ L + ++ A ARNI I I+F E+ S + I+G+ G
Sbjct: 630 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 689
Query: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661
P F + + AV +H+++P+FY+E+KI+LP +L HHLL TF+H+SC S
Sbjct: 690 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 749
Query: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720
VET +GYSWLP+L + R+ T +PV+ LP Y + + P IKW +G K
Sbjct: 750 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 808
Query: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
+ I VS+V+TQD HL FF C ES AL +EL + L
Sbjct: 809 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 855
Query: 781 NSSRLEPLVLFLHLVLDKLFQL 802
++ ++ FL +L++LF++
Sbjct: 856 HAMEGHVMIAFLPTILNQLFRV 877
Score = 37.0 bits (84), Expect = 0.20
Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 11/126 (8%)
Query: 59 VEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVEL 114
+EP+D+E +++ + +E+ F DD ++ C T+ EE L
Sbjct: 48 IEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL 107
Query: 115 DPHVRDCVQTYIREWLIVNRKNQG-SPEICGFKKTGSRKDFHKTLPKQTFE-SETLECSE 172
V +C++TY +W +VN K + S E F++ ++ LP +E E ++ E
Sbjct: 108 --FVTECIKTYNSDWHLVNYKYEDYSGE---FRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
Query: 173 PAAQAG 178
AA G
Sbjct: 163 DAASLG 168
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 515 bits (1327), Expect = e-145
Identities = 384/1230 (31%), Positives = 583/1230 (47%), Gaps = 196/1230 (15%)
Query: 950 AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003
A P AS+ K HEEL M + + + KY+WFFF++L+KSMAQH+ K
Sbjct: 921 AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 980
Query: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEK-MNISLAFFLYDLLSL 1062
R RF + + T+VN++ I ++N +A K N SLA F+ +
Sbjct: 981 VKLLRNQRFPASYHHAVETVVNMLMPHITQKF----RDNPEASKNANHSLAVFIKRCFTF 1036
Query: 1063 MDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTS 1122
MDRGFVF I +Y S + + TL + EFLR++C+HEHY+ LNL
Sbjct: 1037 MDRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL----------- 1083
Query: 1123 PCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQ 1182
P P +QD ++ + LT E+ + HFL GLL E+ AL + +V+
Sbjct: 1084 PMPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVR 1133
Query: 1183 RKAVSAIHSL------------------------------------LSSHDLDPRCVKPE 1206
A+S + +L ++ D+ P V
Sbjct: 1134 LIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAG 1193
Query: 1207 VKVKIAALYLPLVGIIL--------------DALPQLCDFTVADTRRYRTSGSDEEQEGA 1252
+ VK +L LP V ++ D L + T S +
Sbjct: 1194 MTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSR 1253
Query: 1253 GAINQNVALAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTR----------NLMICFLW 1302
G++ + GN+ + S S ++Q + L R +L++CFL+
Sbjct: 1254 GSLISTDS----GNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLY 1309
Query: 1303 IMKN-ADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVK 1361
I+K+ +D +L W +++L + +C+ F+Y GK+
Sbjct: 1310 ILKSMSDDALFTYW-NKASTSELMDFFTISEVCLHQFQYMGKRYI--------------- 1353
Query: 1362 ARLEEALLRGEGARGEMMRRRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQ 1421
AR MM R + L+ +L + H + A++
Sbjct: 1354 ------------ARTGMMHARL---QQLGSLDNSLTFNHSYGH----------SDADVLH 1388
Query: 1422 EALISGNLATEAHLIILDMQENIIQASSALDCKDS----LLGGVLRVLVNSLNCDQSTTY 1477
++L+ N+ATE L LD A D L+ V V + L QS T
Sbjct: 1389 QSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETA 1448
Query: 1478 LTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFS 1537
L + F LR+LI KF +E + C LC+++L C+S + R++A LY LMR +
Sbjct: 1449 LKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNN 1508
Query: 1538 FGATS--NFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQ 1595
F T +F R +QV +S++ L+ ++SL I + D ++ T F +
Sbjct: 1509 FDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSD 1568
Query: 1596 VEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKK 1655
V++L + ++L T +M+E + DPEML+DL Y +AKSY ++P+LR TWL +MA H K
Sbjct: 1569 VKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKN 1628
Query: 1656 KCYTEAAMCLVHAAALVAEYLSMLEDHSYLPV--------------------GSVSFQNI 1695
+EAAMC VH ALVAEYL+ E + P G +F+ I
Sbjct: 1629 GDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVI 1688
Query: 1696 SSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLV 1755
+ N+ EE+ + ED D +F E L+ LLEQ A+ YE + ++YKL+
Sbjct: 1689 TPNIDEEASMMEDVGMQDV-------HFNEDVLMELLEQCADGLWKAERYELIADIYKLI 1741
Query: 1756 IPILEAHREFRKLTLTHSKLQRAFDSIVNKDH--KRMFGTYFRVGFFGSK---------- 1803
IPI E R+F +L + L RA+ + H +R+ GTYFRV FFG
Sbjct: 1742 IPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSET 1801
Query: 1804 -----FGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDP 1858
F D D +E++YKEP +T L EIS RL Y FG+E V++I+DS V+ LD
Sbjct: 1802 DVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDS 1861
Query: 1859 NKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTV 1918
AYIQ+T V P+FDE E+++R T FE++ N+RRFM+ PFT G+ +G + EQ +R T+
Sbjct: 1862 KYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTI 1921
Query: 1919 LTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQ 1978
LT +H FPY+K RI V+ + L PIEVAI++M KK +L + D LQ+ LQ
Sbjct: 1922 LTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQ 1981
Query: 1979 GSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRL---CFKEFIMRCGEAVEKNKRLI 2035
GSV VN GPL A+ FL + + K Y NK++L F++F+ CG+A+ N+RLI
Sbjct: 1982 GSVSVQVNAGPLAYARAFLDD--TNTKRY-PDNKVKLLKEVFRQFVEACGQALAVNERLI 2038
Query: 2036 TADQREYQQELKKNYNKLKENLRPMIERKI 2065
DQ EYQ+E+K NY ++ + L ++ ++
Sbjct: 2039 KEDQLEYQEEMKANYREMAKELSEIMHEQL 2068
Score = 273 bits (698), Expect = 1e-72
Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)
Query: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280
++ E ++ + +LF L P + D P + +E G RILVK L F ++
Sbjct: 324 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 383
Query: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323
+EP F +++L+D+K +KIS +FH DLN + L +P++
Sbjct: 384 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 443
Query: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373
AA + +FSVT P DI+LV +IEKVLQ G I CAEPY +K SD
Sbjct: 444 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 500
Query: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433
K +K+ K QA CQRLG+YRMPFAWA
Sbjct: 501 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 529
Query: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493
RTL + + +L++N S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 530 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 571
Query: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551
+ + + I G L + I + +P K F ++T E+ EF P
Sbjct: 572 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 630
Query: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607
+ P+T+Y N LYVYP+ L + ++ A ARNI I I+F E+ S + I+G+ G
Sbjct: 631 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 690
Query: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661
P F + + AV +H+++P+FY+E+KI+LP +L HHLL TF+H+SC S
Sbjct: 691 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 750
Query: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720
VET +GYSWLP+L + R+ T +PV+ LP Y + + P IKW +G K
Sbjct: 751 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 809
Query: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
+ I VS+V+TQD HL FF C ES AL +EL + L
Sbjct: 810 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 856
Query: 781 NSSRLEPLVLFLHLVLDKLFQL 802
++ ++ FL +L++LF++
Sbjct: 857 HAMEGHVMIAFLPTILNQLFRV 878
Score = 39.7 bits (91), Expect = 0.031
Identities = 47/170 (27%), Positives = 75/170 (44%), Gaps = 20/170 (11%)
Query: 20 SSAEIRKQFTLP---PNLGQYHRQSIS--TSGFPSLQLPQFYDPVEPVDFEGLLMTHLNS 74
+SAE RK FT P RQS+S G L P+ +EP+D+E +++
Sbjct: 9 ASAETRK-FTRALSKPGTAAELRQSVSEVVRGSVLLAKPKL---IEPLDYENVIVQKKTQ 64
Query: 75 LDVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVELDPHVRDCVQTYIREWL 130
+ +E+ F DD ++ C T+ EE L V +C++TY +W
Sbjct: 65 ILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL--FVTECIKTYNSDWH 122
Query: 131 IVNRKNQG-SPEICGFKKTGSRKDFHKTLPKQTFE-SETLECSEPAAQAG 178
+VN K + S E F++ ++ LP +E E ++ E AA G
Sbjct: 123 LVNYKYEDYSGE---FRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLG 169
>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
Length = 1253
Score = 273 bits (698), Expect = 1e-72
Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)
Query: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280
++ E ++ + +LF L P + D P + +E G RILVK L F ++
Sbjct: 323 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 382
Query: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323
+EP F +++L+D+K +KIS +FH DLN + L +P++
Sbjct: 383 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 442
Query: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373
AA + +FSVT P DI+LV +IEKVLQ G I CAEPY +K SD
Sbjct: 443 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 499
Query: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433
K +K+ K QA CQRLG+YRMPFAWA
Sbjct: 500 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 528
Query: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493
RTL + + +L++N S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 529 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 570
Query: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551
+ + + I G L + I + +P K F ++T E+ EF P
Sbjct: 571 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 629
Query: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607
+ P+T+Y N LYVYP+ L + ++ A ARNI I I+F E+ S + I+G+ G
Sbjct: 630 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 689
Query: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661
P F + + AV +H+++P+FY+E+KI+LP +L HHLL TF+H+SC S
Sbjct: 690 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 749
Query: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720
VET +GYSWLP+L + R+ T +PV+ LP Y + + P IKW +G K
Sbjct: 750 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 808
Query: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
+ I VS+V+TQD HL FF C ES AL +EL + L
Sbjct: 809 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 855
Query: 781 NSSRLEPLVLFLHLVLDKLFQL 802
++ ++ FL +L++LF++
Sbjct: 856 HAMEGHVMIAFLPTILNQLFRV 877
Score = 138 bits (348), Expect = 5e-32
Identities = 94/286 (32%), Positives = 143/286 (50%), Gaps = 32/286 (11%)
Query: 950 AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003
A P AS+ K HEEL M + + + KY+WFFF++L+KSMAQH+ K
Sbjct: 920 AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 979
Query: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLM 1063
R RF + + T+VN++ I K + E ++ N SLA F+ + M
Sbjct: 980 VKLLRNQRFPASYHHAVETVVNMLMPHITQ---KFRDNPEASKNANHSLAVFIKRCFTFM 1036
Query: 1064 DRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSP 1123
DRGFVF I +Y S + + TL + EFLR++C+HEHY+ LNL P
Sbjct: 1037 DRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL-----------P 1083
Query: 1124 CPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQR 1183
P +QD ++ + LT E+ + HFL GLL E+ AL + +V+
Sbjct: 1084 MPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVRL 1133
Query: 1184 KAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL 1229
A+S + +LL H D R + +IA LYLPL G++++ + ++
Sbjct: 1134 IAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRI 1179
Score = 37.0 bits (84), Expect = 0.20
Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 11/126 (8%)
Query: 59 VEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVEL 114
+EP+D+E +++ + +E+ F DD ++ C T+ EE L
Sbjct: 48 IEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL 107
Query: 115 DPHVRDCVQTYIREWLIVNRKNQG-SPEICGFKKTGSRKDFHKTLPKQTFE-SETLECSE 172
V +C++TY +W +VN K + S E F++ ++ LP +E E ++ E
Sbjct: 108 --FVTECIKTYNSDWHLVNYKYEDYSGE---FRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
Query: 173 PAAQAG 178
AA G
Sbjct: 163 DAASLG 168
>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
Length = 1254
Score = 273 bits (698), Expect = 1e-72
Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)
Query: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280
++ E ++ + +LF L P + D P + +E G RILVK L F ++
Sbjct: 324 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 383
Query: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323
+EP F +++L+D+K +KIS +FH DLN + L +P++
Sbjct: 384 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 443
Query: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373
AA + +FSVT P DI+LV +IEKVLQ G I CAEPY +K SD
Sbjct: 444 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 500
Query: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433
K +K+ K QA CQRLG+YRMPFAWA
Sbjct: 501 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 529
Query: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493
RTL + + +L++N S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 530 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 571
Query: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551
+ + + I G L + I + +P K F ++T E+ EF P
Sbjct: 572 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 630
Query: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607
+ P+T+Y N LYVYP+ L + ++ A ARNI I I+F E+ S + I+G+ G
Sbjct: 631 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 690
Query: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661
P F + + AV +H+++P+FY+E+KI+LP +L HHLL TF+H+SC S
Sbjct: 691 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 750
Query: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720
VET +GYSWLP+L + R+ T +PV+ LP Y + + P IKW +G K
Sbjct: 751 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 809
Query: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
+ I VS+V+TQD HL FF C ES AL +EL + L
Sbjct: 810 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 856
Query: 781 NSSRLEPLVLFLHLVLDKLFQL 802
++ ++ FL +L++LF++
Sbjct: 857 HAMEGHVMIAFLPTILNQLFRV 878
Score = 138 bits (348), Expect = 5e-32
Identities = 94/286 (32%), Positives = 143/286 (50%), Gaps = 32/286 (11%)
Query: 950 AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003
A P AS+ K HEEL M + + + KY+WFFF++L+KSMAQH+ K
Sbjct: 921 AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 980
Query: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLM 1063
R RF + + T+VN++ I K + E ++ N SLA F+ + M
Sbjct: 981 VKLLRNQRFPASYHHAVETVVNMLMPHITQ---KFRDNPEASKNANHSLAVFIKRCFTFM 1037
Query: 1064 DRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSP 1123
DRGFVF I +Y S + + TL + EFLR++C+HEHY+ LNL P
Sbjct: 1038 DRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL-----------P 1084
Query: 1124 CPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQR 1183
P +QD ++ + LT E+ + HFL GLL E+ AL + +V+
Sbjct: 1085 MPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVRL 1134
Query: 1184 KAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL 1229
A+S + +LL H D R + +IA LYLPL G++++ + ++
Sbjct: 1135 IAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRI 1180
Score = 39.7 bits (91), Expect = 0.031
Identities = 47/170 (27%), Positives = 75/170 (44%), Gaps = 20/170 (11%)
Query: 20 SSAEIRKQFTLP---PNLGQYHRQSIS--TSGFPSLQLPQFYDPVEPVDFEGLLMTHLNS 74
+SAE RK FT P RQS+S G L P+ +EP+D+E +++
Sbjct: 9 ASAETRK-FTRALSKPGTAAELRQSVSEVVRGSVLLAKPKL---IEPLDYENVIVQKKTQ 64
Query: 75 LDVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVELDPHVRDCVQTYIREWL 130
+ +E+ F DD ++ C T+ EE L V +C++TY +W
Sbjct: 65 ILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL--FVTECIKTYNSDWH 122
Query: 131 IVNRKNQG-SPEICGFKKTGSRKDFHKTLPKQTFE-SETLECSEPAAQAG 178
+VN K + S E F++ ++ LP +E E ++ E AA G
Sbjct: 123 LVNYKYEDYSGE---FRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLG 169
>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
Length = 2030
Score = 73.9 bits (180), Expect = 2e-12
Identities = 82/344 (23%), Positives = 146/344 (42%), Gaps = 25/344 (7%)
Query: 1730 GLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKR 1789
GL + F+ G +E + + + E+ +++ L+ +D+I+ + +R
Sbjct: 1292 GLCRKIIHYFNKGKSWEFGIPLCRELACQYESLYDYQSLSWIRKMEASYYDNIM--EQQR 1349
Query: 1790 MFGTYFRVGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDST 1849
+ +FRVGF+G KF F + RLEAF Q +EF + +
Sbjct: 1350 LEPEFFRVGFYGRKF------PFFLRNKEYVCRGHDYERLEAFQ-QRMLSEFPQAVAMQH 1402
Query: 1850 P--VDKTKLDPNKAYIQITFVEP---YFDEYEM---KDRVTYFEKNFNLRRFMYTTPFTL 1901
P D L + Y+QI V P Y D +M DRV F + N+R+F Y PF
Sbjct: 1403 PNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHK 1462
Query: 1902 EGRPR-GELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLA 1960
+ + E + T LT H+ P I V ++E ++P+E AI+ ++ K +L
Sbjct: 1463 GPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELR 1522
Query: 1961 VAINQEP-----PDAKMLQMVLQGSVGATVNQGPLEVAQVFLAE--IPADPKLYRHHNKL 2013
I+Q + +L M L G + A VN G + F + I P +L
Sbjct: 1523 SLISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYINKHPGDAEKITQL 1582
Query: 2014 RLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENL 2057
+ +E + G + +++ + + R ++L + ++ +L
Sbjct: 1583 KELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASL 1626
Score = 45.4 bits (106), Expect = 6e-04
Identities = 69/294 (23%), Positives = 124/294 (42%), Gaps = 27/294 (9%)
Query: 545 LEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARN---ITIKIQFMCGEDASNAMPVI 601
L FP +V +P + RN LY+ ++ +F S + +T+ + + GE + + +
Sbjct: 409 LGFP--DVIMPGDI-RNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISL- 464
Query: 602 FGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS 661
SG ++ V YH+ SP + E +K+ +P HL F F H S + K
Sbjct: 465 ---GSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDK---G 518
Query: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGV 721
+ L G+++ ++ ++ + + K N S + + L P K E + G
Sbjct: 519 EKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDEN-STFNNHALYLGLPCCK--EDYNGC 575
Query: 722 FNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLN 781
NI SS+ Q + E FF +++T + +L + A + + L
Sbjct: 576 PNIP----SSLIFQRSTKESFFISTQLSSTKLTQNVDLL-ALLKWKAFPDRIMDVLGRLR 630
Query: 782 SSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSK 835
E +V FL +LD LF +++ T + F+S+V I N L + K
Sbjct: 631 HVSGEEIVKFLQDILDTLF------VILDDNTEKYGLLVFQSLVFIINLLRDIK 678
>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
Length = 1966
Score = 71.2 bits (173), Expect = 1e-11
Identities = 85/337 (25%), Positives = 144/337 (42%), Gaps = 30/337 (8%)
Query: 1739 FSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVG 1798
F G +E + + + E++ ++R L+ +D I+ D +R+ +FRVG
Sbjct: 1263 FDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIM--DQQRLEPEFFRVG 1320
Query: 1799 FFGSKFGD-LDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVI--KDSTPVDKTK 1855
F+G KF L +EFV + RLEAF + EF I + + D+T
Sbjct: 1321 FYGKKFPFFLRNKEFVCRGHDY-------ERLEAFQQRMLN-EFPHAIAMQHANQPDETI 1372
Query: 1856 LDPNKAYIQITFVEPYFDEYEM------KDRVTYFEKNFNLRRFMYTTPFTLEGRPR-GE 1908
Y+QI V P + E+ D + F K ++ +F Y PF + + E
Sbjct: 1373 FQAEAQYLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENE 1432
Query: 1909 LHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQ--- 1965
+ T L + + P I V ++E ++P+E AIE ++ K QL I+Q
Sbjct: 1433 FKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQT 1492
Query: 1966 -EPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAE--IPADPKLYRHHNKLRLCFKE--F 2020
+ + L M L G + A VN G + F + I + P+ +LR E
Sbjct: 1493 RQMQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQ 1552
Query: 2021 IMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENL 2057
I+ G AV +++ + D R ++L + +K +L
Sbjct: 1553 ILEFGLAV--HEKFVPQDMRPLHKKLVDQFFVMKSSL 1587
Score = 46.6 bits (109), Expect = 3e-04
Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Query: 560 RNLLYVYPQRLNFVNKLAS-ARNITIKIQFMCGEDASNAMPVIFGKSSGPEFLQEVYTAV 618
RN LY+ +R F S ARN+ + + + + + FG P E ++ V
Sbjct: 401 RNDLYITIERGEFEKGGKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPA--SEYHSFV 458
Query: 619 TYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASVETLLGYSWLPIL 674
YHN SP + E +K+ +P H+ F F H S ++K + L G+S++P++
Sbjct: 459 LYHNNSPRWSELLKLPIPVDKFRGAHIRFEFRHCSTKEK---GEKKLFGFSFVPLM 511
Score = 35.4 bits (80), Expect = 0.59
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Query: 846 CLLASYVHYVFRLPEVQRD-VPKSGAPTALL-----DPRSYHTYGRTSAAAVSSKLLQAR 899
C+ AS VH+ P V R+ P S +P P SY R S++++SS+
Sbjct: 1595 CMQASPVHFPNGSPRVCRNSAPASVSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQA---- 1650
Query: 900 VMSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKH 959
S+ ++ G ++DE V N+ S S S + +S APSS A S KH
Sbjct: 1651 --SAEVSNITGQSESSDE-VFNMQPSPSTSSLSSTHSASPNVTSSAPSSARASPLLSDKH 1707
Query: 960 FH 961
H
Sbjct: 1708 KH 1709
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 67.4 bits (163), Expect = 1e-10
Identities = 113/488 (23%), Positives = 185/488 (37%), Gaps = 75/488 (15%)
Query: 1592 FPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASP--DLRLTWLQNMA 1649
F V LL NL + Y T+ M++ E E M + Y+ D+ + +L +
Sbjct: 1193 FALLVSSLLENL--LDYRTIIMQD--ESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLR 1248
Query: 1650 EKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDT 1709
+ H + YTEAA L+ A L+ D +P
Sbjct: 1249 DLHRDCENYTEAAYTLLLHAELL-----QWSDKPCVP---------------------HL 1282
Query: 1710 LSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHR-EFRKL 1768
L D V Q E L ++ F G ++E ++ K + E+ ++ L
Sbjct: 1283 LQKDSYYVYTQQELKEK----LYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGL 1338
Query: 1769 TLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFFGSKFGD-LDEQEFVYKEPAITKLPEISH 1827
K +++I+ R YF VG++G F L + F+Y+ + + S
Sbjct: 1339 GNLLKKRASFYENIIKA--MRPQPEYFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSL 1396
Query: 1828 RLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEP-------YFDEYEMKDR 1880
RL + E + +TP + K Y+Q V+P Y D+ +
Sbjct: 1397 RLLTQFPNA------EKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQI 1450
Query: 1881 VTYFEKNFNLRRFMYTTPFTL-EGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEE 1939
+ Y+ N +++F Y+ PF E P E + T TT + FP I V Q
Sbjct: 1451 LNYYRAN-EVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQIST 1509
Query: 1940 FVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKM----LQMVLQGSVGATVNQGPLEVAQV 1995
++P+E AIE M+ +++ + Q D + L M+L G V V G +
Sbjct: 1510 EEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKA 1569
Query: 1996 FLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKE 2055
F E K + H + + E VE KRLI + ++ + KL E
Sbjct: 1570 FFTE-----KYLQEHPEDQ-----------EKVELLKRLIALQMPLLTEGIRIHGEKLTE 1613
Query: 2056 NLRPMIER 2063
L+P+ ER
Sbjct: 1614 QLKPLHER 1621
Score = 41.6 bits (96), Expect = 0.008
Identities = 64/260 (24%), Positives = 116/260 (44%), Gaps = 32/260 (12%)
Query: 606 SGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASVETL 665
+G E + E + V Y K P +YE VK+ + + H+ FTF H S Q+ + S E
Sbjct: 488 AGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETRDKS-ERA 546
Query: 666 LGYSWLPILLNE--RLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFN 723
G +++ ++ + LQ G + L V N M A K L P K K
Sbjct: 547 FGVAFVKLMNPDGTTLQDGRHDLVV---YKGDNKKMEDA-KFYLTLPGTKMEMEEK---- 598
Query: 724 IEVQA----VSSVHTQDNHLEKF---FTLCHSLESQVTFPIRVLDQKISEMALEHELKLS 776
E+QA V+ ++D+ + F +C + +Q + +L+ + + ++H LK
Sbjct: 599 -ELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLK-K 656
Query: 777 IICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKD 836
++ ++ +V FL LD LF + M+ + + F+++V I + + +
Sbjct: 657 LMEVDGGE---IVKFLQDTLDALFNI----MMEMSDSETYDFLVFDALVFIISLIGD--- 706
Query: 837 LSKDQHGRNCLLASYVHYVF 856
K QH N +L +Y++ F
Sbjct: 707 -IKFQH-FNPVLETYIYKHF 724
>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
Length = 1830
Score = 63.5 bits (153), Expect = 2e-09
Identities = 68/280 (24%), Positives = 117/280 (41%), Gaps = 30/280 (10%)
Query: 1794 YFRVGFFGSKFGD-LDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVD 1852
YF VG++G F L + F+Y+ + + +L Q AE + S P D
Sbjct: 1342 YFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT---QFPNAEKMNTT--SAPGD 1396
Query: 1853 KTKLDPNKAYIQITFVEPYFDEYE------MKDRVTYFEKNFNLRRFMYTTPF---TLEG 1903
K P + YIQ V+P DE+ + D++ F K+ ++RF Y+ P T++
Sbjct: 1397 DVKNAPGQ-YIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVD- 1454
Query: 1904 RPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAI 1963
P E + T T + P I V+ + ++P+E AIE M ++ + I
Sbjct: 1455 -PENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMI 1513
Query: 1964 NQEPPDAKM----LQMVLQGSVGATVNQGPLEVAQVFLAE-----IPADPKLYRHHNKLR 2014
NQ D + L M+L G V V G + + F E P D H L
Sbjct: 1514 NQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLI 1573
Query: 2015 LCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLK 2054
F+ G ++ +++ ++ + R + +++ + LK
Sbjct: 1574 AWQIPFL---GAGIKIHEKRVSDNLRPFHDRMEECFKNLK 1610
Score = 40.0 bits (92), Expect = 0.024
Identities = 81/340 (23%), Positives = 136/340 (40%), Gaps = 48/340 (14%)
Query: 532 PFPENRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNF--VNKLASARNITIKIQFM 589
P +RT L FP E+ +P V RN +Y+ + +F NK + RN+ + I +
Sbjct: 398 PHLVDRTTVVARKLGFP--EIIMPGDV-RNDIYITLLQGDFDKYNK-TTQRNVEV-IMCV 452
Query: 590 CGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTF 649
C ED +P +G + + E + V Y K P + E VK+ +P + HL F F
Sbjct: 453 CAEDGKT-LPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMF 511
Query: 650 YH-ISCQQKQGASVETLLGYSWLPILLNERLQTGSYCLPVA---LEKLP--------PNY 697
H S + K + Y L L G + L V +K+ P+Y
Sbjct: 512 RHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSY 571
Query: 698 SMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPI 757
H K + + G ++ + V S+ T +C + +Q +
Sbjct: 572 RHHVENK----GATLSRSSSSVGGLSVSSRDVFSIST---------LVCSTKLTQNVGLL 618
Query: 758 RVLDQKISEMALEHEL-KLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANF 816
+L ++ L+ L KL I+ E +V FL LD LF + M+ Q+ +
Sbjct: 619 GLLKWRMKPQLLQENLEKLKIV-----DGEEVVKFLQDTLDALFNI----MMEHSQSDEY 669
Query: 817 SQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVF 856
F++++ I + + K QH N +L +Y+ F
Sbjct: 670 DILVFDALIYIIGLIAD----RKFQH-FNTVLEAYIQQHF 704
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 58.2 bits (139), Expect = 9e-08
Identities = 101/475 (21%), Positives = 188/475 (39%), Gaps = 60/475 (12%)
Query: 1598 ELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQA--SPDLRLTWLQNMAEKHTKK 1655
E L + +I++D E+ E M + Y+ ++ + +L + + H +
Sbjct: 1179 ERLLDYRTIMHD--------ENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKEC 1230
Query: 1656 KCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDED 1715
YTEAA L+ A L+ + H G +Q + L+E + E D+
Sbjct: 1231 DNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDG---YQATTQGQLKEQLYQEIIHYFDK- 1286
Query: 1716 GVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKL 1775
G+ + E+ + L ++ AE + NE++ ++ +L+ K
Sbjct: 1287 ----GKMWEEA--IALGKELAEQYE--------NEMF-----------DYEQLSELLKKQ 1321
Query: 1776 QRAFDSIVNKDHKRMFGTYFRVGFFGSKFGD-LDEQEFVYKEPAITKLPEISHRLEAFYG 1834
+ +++IV + YF VG++G F L + F+Y+ + + RL
Sbjct: 1322 AQFYENIVKVIRPKP--DYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLT--- 1376
Query: 1835 QCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFD-----EYEMKDRVTYFEKNFN 1889
Q AE ++ S P D K P + YIQ V+P D + +++ F +
Sbjct: 1377 QFPNAEKMKTT--SPPGDDIKNSPGQ-YIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNE 1433
Query: 1890 LRRFMYTTPFTL-EGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVA 1948
++RF Y+ P E P E + T+ TT + P I V ++P+E A
Sbjct: 1434 VQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENA 1493
Query: 1949 IEDMKKKTLQLAVAINQEPPDAKM----LQMVLQGSVGATVNQGPLEVAQVFLAE--IPA 2002
IE M+ ++ + Q D + L M+L G V V G + F + +
Sbjct: 1494 IETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQE 1553
Query: 2003 DPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENL 2057
P+ + KL+ I E + + +T R + + ++ + +LKE +
Sbjct: 1554 HPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKV 1608
Score = 49.3 bits (116), Expect = 4e-05
Identities = 70/310 (22%), Positives = 133/310 (42%), Gaps = 21/310 (6%)
Query: 531 KPFPE--NRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNF-VNKLASARNITIKIQ 587
K FP +RT FP E+ +P V RN +YV + +F +A+N+ + +
Sbjct: 397 KEFPHLVDRTTAVARKTGFP--EIIMPGDV-RNDIYVTLVQGDFDKGSKTTAKNVEVTVS 453
Query: 588 FMCGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLF 647
+ ED VIF +G E + E + + Y K P ++E VK+ +P + HL F
Sbjct: 454 -VYDEDGKRLEHVIF-PGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRF 511
Query: 648 TFYHISCQQKQGASVETLLGYSWLPILLNE--RLQTGSYCLPVALEKLPPNYSMHSAEKV 705
TF H S Q + S E + +++ ++ + L+ G + L V K +A +
Sbjct: 512 TFRHRSSQDSKDKS-EKIFALAFVKLMRYDGTTLRDGEHDLIV--YKAEAKKLEDAATYL 568
Query: 706 PLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKIS 765
L + + E +Q++ S + + +C + +Q + +L + +
Sbjct: 569 SLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSN 628
Query: 766 EMALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVV 825
L+ L+ ++ ++ +V FL LD LF + M+ ++ F F+++V
Sbjct: 629 TSLLQQNLR-QLMKVDGGE---VVKFLQDTLDALFNI----MMENSESETFDTLVFDALV 680
Query: 826 AIANSLHNSK 835
I + + K
Sbjct: 681 FIIGLIADRK 690
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 36.6 bits (83), Expect = 0.27
Identities = 41/164 (25%), Positives = 72/164 (43%), Gaps = 24/164 (14%)
Query: 1851 VDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPF----------T 1900
++ +LD N +++ + YF E K + Y+ K LRR Y TP T
Sbjct: 2608 LEDVELDDN-IRVEVVSMCKYFQESVKKLSLDYYNK---LRRHNYVTPTSYLELILTFKT 2663
Query: 1901 LEGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLA 1960
L R E+ RN LT + + ++++V+Q+E L P + + +T ++
Sbjct: 2664 LLNSKRQEV--AMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSE---ETAKMM 2718
Query: 1961 VAINQEPPDAKMLQMVLQ-----GSVGATVNQGPLEVAQVFLAE 1999
V I E +A ++++Q +V A + QG + LAE
Sbjct: 2719 VKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAE 2762
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 35.0 bits (79), Expect = 0.77
Identities = 31/143 (21%), Positives = 69/143 (48%), Gaps = 16/143 (11%)
Query: 1342 GKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGE------MMRRRAPGN--DRFPG-- 1391
G D + + L+ + V+ L + R +G RG ++RR+ DR P
Sbjct: 262 GSADLDDMKSHRLEDNPGVRRHLVKKPSRTQGGRGSPSGLAPILRRKKKKKKLDRRPHEV 321
Query: 1392 ---LNENLRWKKEQTHWRQANEKLDKTKAELDQEALISG--NLATEAHLIILDMQENIIQ 1446
LNE + + ++ HWR+ + K + ++++E G ++A+ + +L+++ I
Sbjct: 322 FVELNELMLDRSQEPHWRETARWI-KFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 380
Query: 1447 ASSALDCKDSLLGGVLRVLVNSL 1469
++ LD + + L G+ ++V ++
Sbjct: 381 GAALLDLEQTTLPGIAHLVVETM 403
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 35.0 bits (79), Expect = 0.77
Identities = 31/143 (21%), Positives = 69/143 (48%), Gaps = 16/143 (11%)
Query: 1342 GKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGE------MMRRRAPGN--DRFPG-- 1391
G D + + L+ + V+ L + R +G RG ++RR+ DR P
Sbjct: 289 GSADLDDMKSHRLEDNPGVRRHLVKKPSRTQGGRGSPSGLAPILRRKKKKKKLDRRPHEV 348
Query: 1392 ---LNENLRWKKEQTHWRQANEKLDKTKAELDQEALISG--NLATEAHLIILDMQENIIQ 1446
LNE + + ++ HWR+ + K + ++++E G ++A+ + +L+++ I
Sbjct: 349 FVELNELMLDRSQEPHWRETARWI-KFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 407
Query: 1447 ASSALDCKDSLLGGVLRVLVNSL 1469
++ LD + + L G+ ++V ++
Sbjct: 408 GAALLDLEQTTLPGIAHLVVETM 430
>gi|156104862 ankyrin repeat domain 38 [Homo sapiens]
Length = 995
Score = 34.7 bits (78), Expect = 1.0
Identities = 15/43 (34%), Positives = 21/43 (48%)
Query: 100 CRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSPEI 142
CR L LPE G D +R + T +EW V+ + SP +
Sbjct: 755 CRALSQHLPETGTTTDQLLRQSLNTISQEWFRVSSRKSSSPAV 797
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 34.3 bits (77), Expect = 1.3
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 39 RQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPK 98
RQ ++ + SL L F+ VE L++ N QL +++ D + +D V +
Sbjct: 677 RQGLTVLTWSSLTLESFFQEVE------LVLDMFN----QLLKKISDLCEMHIDTVLK-E 725
Query: 99 ECRTLQPSLPEEGVELDPHVRDCVQTYIREWL-IVNRKNQ 137
+T+ SLPE G + +TY +EW I+N K++
Sbjct: 726 IAKTVLISLPESGATKVEDMLTLNETYTKEWADILNHKSK 765
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 33.1 bits (74), Expect = 2.9
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Query: 1119 APTSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDA----- 1173
A +P P I + C D + + + LT+ H L LAAAL A
Sbjct: 373 AACAPEPGIPGETRGPCFLAGDGRASEVPSLTA----LHTLWLREHNRLAAALKALNAHW 428
Query: 1174 EGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPE 1206
+ + + RK V A+H +++ D PR + PE
Sbjct: 429 SADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 33.1 bits (74), Expect = 2.9
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Query: 1119 APTSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDA----- 1173
A +P P I + C D + + + LT+ H L LAAAL A
Sbjct: 373 AACAPEPGIPGETRGPCFLAGDGRASEVPSLTA----LHTLWLREHNRLAAALKALNAHW 428
Query: 1174 EGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPE 1206
+ + + RK V A+H +++ D PR + PE
Sbjct: 429 SADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 33.1 bits (74), Expect = 2.9
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Query: 1119 APTSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDA----- 1173
A +P P I + C D + + + LT+ H L LAAAL A
Sbjct: 373 AACAPEPGIPGETRGPCFLAGDGRASEVPSLTA----LHTLWLREHNRLAAALKALNAHW 428
Query: 1174 EGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPE 1206
+ + + RK V A+H +++ D PR + PE
Sbjct: 429 SADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
>gi|52630429 nuclear factor, interleukin 3 regulated [Homo sapiens]
Length = 462
Score = 32.3 bits (72), Expect = 5.0
Identities = 60/263 (22%), Positives = 97/263 (36%), Gaps = 43/263 (16%)
Query: 190 GKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEED 249
GK +AC R PD++ + + E K NE A+R+ + L D
Sbjct: 53 GKNKSSACRRK-REFIPDEKKDAMYW----EKRRKNNEAAKRSREKRRL---------ND 98
Query: 250 AVEIRPVPECPKEHLGNRILVKLLTLKFEI--------EIEPLFASIALY--DVKERKKI 299
V + +E+ + + L LKF + EI+ L S A+Y D + K
Sbjct: 99 LVLENKLIALGEENATLKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSKS- 157
Query: 300 SENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIG 359
F+ H PS+ +SS S SD+ V +E + G
Sbjct: 158 -----------NVSSFVDEHEPSMVSSSCISVIKHSPQSSLSDVSEVSSVEHTQESSVQG 206
Query: 360 DCAEP---YTVIK----ESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFF 412
C P + +IK E + + + ++ A + +G ++ +P L
Sbjct: 207 SCRSPENKFQIIKQEPMELESYTREPRDDRGSYTASIYQNYMGNSFSGYSHSPPLLQVNR 266
Query: 413 NVSTLEREVTDVDSVVGRSSVGE 435
+ S R D VVG+SS GE
Sbjct: 267 SSSNSPRTSETDDGVVGKSSDGE 289
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 32.3 bits (72), Expect = 5.0
Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 17/122 (13%)
Query: 1939 EFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLA 1998
E L+P E+ + +K+ L A + DA QMVL S +GPLE LA
Sbjct: 1482 ERALSPAELRALEAEKRALWRAARMKSLEQDALRAQMVLSRSQEGRGTRGPLE----RLA 1537
Query: 1999 EIPA-------------DPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQE 2045
E P+ P+ +L L K+F R A+ ++ + ++ +E
Sbjct: 1538 EAPSPAPTPSPTPVEDLGPQTSTSPGRLPLSGKKFDYRAFAALPSSRPVYDIQSPDFAEE 1597
Query: 2046 LK 2047
L+
Sbjct: 1598 LR 1599
>gi|7662454 vasohibin 1 [Homo sapiens]
Length = 365
Score = 32.0 bits (71), Expect = 6.5
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 1743 GLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFR-----V 1797
GL + E+ K +PI + LT+S I K + G YFR V
Sbjct: 152 GLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTY--FSGNYFRHIVLGV 209
Query: 1798 GFFGSKFGDLD---EQEFVYKEPAITKLPEISHRLEAFYGQCF 1837
F G ++G L ++ +YK PA L E+ EA YG+C+
Sbjct: 210 NFAG-RYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCW 251
>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
Length = 490
Score = 32.0 bits (71), Expect = 6.5
Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 13/98 (13%)
Query: 866 PKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGTHSAADEEVKNIMSS 925
P G+P DP+ H Y S+K AR S ++ ++ + S+AD+
Sbjct: 320 PSCGSPVVSGDPKEDHNYS-------SAKSSNARSTSPTSDSISSSSSSADDHY------ 366
Query: 926 KIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHFHEE 963
+ A + S GS + SP+ +KH +E
Sbjct: 367 EFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKE 404
>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
Length = 468
Score = 32.0 bits (71), Expect = 6.5
Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 13/98 (13%)
Query: 866 PKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGTHSAADEEVKNIMSS 925
P G+P DP+ H Y S+K AR S ++ ++ + S+AD+
Sbjct: 298 PSCGSPVVSGDPKEDHNYS-------SAKSSNARSTSPTSDSISSSSSSADDHY------ 344
Query: 926 KIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHFHEE 963
+ A + S GS + SP+ +KH +E
Sbjct: 345 EFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKE 382
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 32.0 bits (71), Expect = 6.5
Identities = 34/173 (19%), Positives = 72/173 (41%), Gaps = 20/173 (11%)
Query: 1560 GRAPDFNE-EHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQE 1618
GR+P+ E +H+RR + + +S+ A+ P Q + + + + +E Q+
Sbjct: 189 GRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQK 248
Query: 1619 DPEMLMDLMYRIAKS-YQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLS 1677
DL +++ ++ ++A PD + W +K + + T + H
Sbjct: 249 ----YHDLAFQVKEAHFKAHPDWK--WCNKDRKKSSSEAKPTSLGLAGGHKET------- 295
Query: 1678 MLEDHSYLPVGSVSFQNISSNVLE---ESVVSEDTLSPDEDGVCAGQYFTESG 1727
+ S G+ + +SS +L ++++S DT +P A + T G
Sbjct: 296 --RERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGG 346
>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
sapiens]
Length = 3258
Score = 31.6 bits (70), Expect = 8.5
Identities = 28/119 (23%), Positives = 50/119 (42%), Gaps = 7/119 (5%)
Query: 405 PISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRLS-ERALSLEENGVGSNFKT 463
PI ++ S+L V+ ++ SSV + QS ++ A+ L E G GS +
Sbjct: 1082 PIGKRNWLKRSSLSGLADGVEDLLDISSVDRLSFIRQSSKVKFTSAVKLSEGGPGSGMEN 1141
Query: 464 STLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCC 522
+FFK+ G D+ L + + V ++ G +R + ++NCC
Sbjct: 1142 GRDEEENFFKRLGCHSFDDHL-----SPNQDGGKSKNVVNL-GAIRQGMKRFQFLLNCC 1194
>gi|122937211 KIAA0368 protein [Homo sapiens]
Length = 2017
Score = 31.6 bits (70), Expect = 8.5
Identities = 23/100 (23%), Positives = 50/100 (50%), Gaps = 16/100 (16%)
Query: 2004 PKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYN----KLKENL-- 2057
P+LYR+ L ++ + A+ +K ++ +E Q+L KN +++E+
Sbjct: 1297 PRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCL 1356
Query: 2058 --------RPM--IERKIPELYKPIFRVESQKRDSFHRSS 2087
RP+ I K+PE+++ +FRV+ ++S +++
Sbjct: 1357 ALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAA 1396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,558,396
Number of Sequences: 37866
Number of extensions: 3352976
Number of successful extensions: 9669
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 9454
Number of HSP's gapped (non-prelim): 101
length of query: 2099
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1981
effective length of database: 13,779,330
effective search space: 27296852730
effective search space used: 27296852730
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.