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Search of human proteins with 236462984
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens]
(194 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens] 387 e-108
gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens] 375 e-104
gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens] 375 e-104
gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens] 375 e-104
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens] 375 e-104
gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens] 375 e-104
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens] 375 e-104
gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens] 375 e-104
gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens] 375 e-104
gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens] 345 2e-95
gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens] 345 2e-95
gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens] 322 1e-88
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 310 4e-85
gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens] 280 4e-76
gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens] 280 7e-76
gi|236461846 neuregulin 1 isoform ndf43c [Homo sapiens] 97 1e-20
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens] 96 2e-20
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens] 96 2e-20
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens] 96 2e-20
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens] 96 2e-20
gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens] 95 3e-20
gi|93102361 palladin [Homo sapiens] 54 1e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 52 3e-07
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 52 4e-07
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 51 5e-07
gi|45594240 limbic system-associated membrane protein [Homo sapi... 51 7e-07
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 50 9e-07
gi|110349717 titin isoform novex-2 [Homo sapiens] 50 9e-07
gi|110349713 titin isoform novex-1 [Homo sapiens] 50 9e-07
gi|110349715 titin isoform N2-B [Homo sapiens] 50 9e-07
>gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens]
Length = 194
Score = 387 bits (995), Expect = e-108
Identities = 194/194 (100%), Positives = 194/194 (100%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECF 180
DSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECF
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECF 180
Query: 181 MVKDLSNPSRYLCK 194
MVKDLSNPSRYLCK
Sbjct: 181 MVKDLSNPSRYLCK 194
>gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens]
Length = 459
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens]
Length = 211
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens]
Length = 420
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
Length = 241
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens]
Length = 637
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
Length = 645
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens]
Length = 640
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens]
Length = 462
Score = 375 bits (964), Expect = e-104
Identities = 193/211 (91%), Positives = 194/211 (91%), Gaps = 17/211 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYV-----------------SSATSTSTTGTSHLV 163
DSASANITIVESNEIITGMPASTEGAYV SS+TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 164 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens]
Length = 177
Score = 345 bits (884), Expect = 2e-95
Identities = 177/194 (91%), Positives = 177/194 (91%), Gaps = 17/194 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECF 180
DSASANITIVESN ATSTSTTGTSHLVKCAEKEKTFCVNGGECF
Sbjct: 121 DSASANITIVESN-----------------ATSTSTTGTSHLVKCAEKEKTFCVNGGECF 163
Query: 181 MVKDLSNPSRYLCK 194
MVKDLSNPSRYLCK
Sbjct: 164 MVKDLSNPSRYLCK 177
>gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
Length = 207
Score = 345 bits (884), Expect = 2e-95
Identities = 177/194 (91%), Positives = 177/194 (91%), Gaps = 17/194 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECF 180
DSASANITIVESN ATSTSTTGTSHLVKCAEKEKTFCVNGGECF
Sbjct: 121 DSASANITIVESN-----------------ATSTSTTGTSHLVKCAEKEKTFCVNGGECF 163
Query: 181 MVKDLSNPSRYLCK 194
MVKDLSNPSRYLCK
Sbjct: 164 MVKDLSNPSRYLCK 177
>gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]
Length = 607
Score = 322 bits (826), Expect = 1e-88
Identities = 161/161 (100%), Positives = 161/161 (100%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
Sbjct: 13 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 72
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATS 153
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATS
Sbjct: 73 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATS 132
Query: 154 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 133 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 173
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 310 bits (795), Expect = 4e-85
Identities = 160/178 (89%), Positives = 161/178 (90%), Gaps = 17/178 (9%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
Sbjct: 13 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 72
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYV----- 148
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYV
Sbjct: 73 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESP 132
Query: 149 ------------SSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
SS+TSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 133 IRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 190
>gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]
Length = 422
Score = 280 bits (717), Expect = 4e-76
Identities = 147/173 (84%), Positives = 148/173 (85%), Gaps = 17/173 (9%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
KK S + ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN
Sbjct: 237 KKEVSRVLCKRCALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 296
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPA 141
KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN
Sbjct: 297 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN-------- 348
Query: 142 STEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
ATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 349 ---------ATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 392
>gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]
Length = 590
Score = 280 bits (715), Expect = 7e-76
Identities = 144/161 (89%), Positives = 144/161 (89%), Gaps = 17/161 (10%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
Sbjct: 13 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 72
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATS 153
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN ATS
Sbjct: 73 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN-----------------ATS 115
Query: 154 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 116 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 156
>gi|236461846 neuregulin 1 isoform ndf43c [Homo sapiens]
Length = 308
Score = 96.7 bits (239), Expect = 1e-20
Identities = 44/45 (97%), Positives = 45/45 (100%)
Query: 150 SATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
+ATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 13 TATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 57
>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
Length = 844
Score = 95.5 bits (236), Expect = 2e-20
Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 31/181 (17%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRL- 326
Query: 129 IVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNP 188
YV+S ++T ++ + H KC E K++CVNGG C+ ++ ++
Sbjct: 327 ------------------YVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQL 368
Query: 189 S 189
S
Sbjct: 369 S 369
>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
Length = 852
Score = 95.5 bits (236), Expect = 2e-20
Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 31/181 (17%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRL- 326
Query: 129 IVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNP 188
YV+S ++T ++ + H KC E K++CVNGG C+ ++ ++
Sbjct: 327 ------------------YVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQL 368
Query: 189 S 189
S
Sbjct: 369 S 369
>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
Length = 858
Score = 95.5 bits (236), Expect = 2e-20
Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 31/181 (17%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRL- 326
Query: 129 IVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNP 188
YV+S ++T ++ + H KC E K++CVNGG C+ ++ ++
Sbjct: 327 ------------------YVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQL 368
Query: 189 S 189
S
Sbjct: 369 S 369
>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
Length = 850
Score = 95.5 bits (236), Expect = 2e-20
Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 31/181 (17%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRL- 326
Query: 129 IVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNP 188
YV+S ++T ++ + H KC E K++CVNGG C+ ++ ++
Sbjct: 327 ------------------YVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQL 368
Query: 189 S 189
S
Sbjct: 369 S 369
>gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens]
Length = 296
Score = 95.1 bits (235), Expect = 3e-20
Identities = 43/44 (97%), Positives = 44/44 (100%)
Query: 151 ATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 194
+TSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 223 STSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 266
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 53.5 bits (127), Expect = 1e-07
Identities = 50/182 (27%), Positives = 85/182 (46%), Gaps = 11/182 (6%)
Query: 18 RGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNEL 77
R S +P SA PA P +++++SQE A GS++ L C + + R +WF G EL
Sbjct: 255 RKSHPQPHSAL--HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGN-PTPRVRWFCEGKEL 311
Query: 78 NRKNKPQNIKIQKKPGK-SELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
+ N P +I+I + G L I +A D+G Y C + G+D+ SA + I ++
Sbjct: 312 H--NTP-DIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 368
Query: 137 TGMPA----STEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYL 192
+ + S GA + T++ + + T V V+ + +P+ YL
Sbjct: 369 SDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYL 428
Query: 193 CK 194
C+
Sbjct: 429 CR 430
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.0 bits (123), Expect = 3e-07
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
A P ++++ E A G CE S ++RF+WFK G E+ +K I+
Sbjct: 3454 AAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIYESDK---CSIRSSKY 3509
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
S L I + + D GEY CK ++ G+ S +A +T+ E+
Sbjct: 3510 ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA 3548
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 11/129 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + + +SQ G ++ CE S E S +WFKN ++ + N+ I +
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISS---NVSISRSRNVY 33189
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIV-----ESNEII--TGMPASTEGAYV 148
L I AS++DSG+Y K + G SA+A++ ++ S E++ T S +G++
Sbjct: 33190 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 33249
Query: 149 SSATSTSTT 157
S + S +
Sbjct: 33250 SQSVQMSAS 33258
Score = 48.1 bits (113), Expect = 5e-06
Identities = 38/158 (24%), Positives = 72/158 (45%), Gaps = 8/158 (5%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +++ +S L C+ + +R WFK+G E+ ++ +I G + L I
Sbjct: 4117 KPLRNVDSVVNGTCRLDCKIAGSLP-MRVSWFKDGKEIAASDR---YRIAFVEGTASLEI 4172
Query: 100 NKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTST-TG 158
+ + D+G + C+ + +G+ +S + + E +T P S + S+ ST G
Sbjct: 4173 IRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT-KPGSKDVLPGSAVCLKSTFQG 4231
Query: 159 TSHLVKCAEKEKTFCVNGGECFMVKDL--SNPSRYLCK 194
++ L K V+GG C++ K+ S+ YL K
Sbjct: 4232 STPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVK 4269
Score = 47.4 bits (111), Expect = 8e-06
Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 35 LPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP K++ + GS + + C+ S + +WFK+G E++ K + + ++
Sbjct: 5235 IPPSFTKKLTKMDKVLGSSIHMECKVSGSLP-ISAQWFKDGKEISTSAKYRLVCHERSVS 5293
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L +N L D+ Y CKV + G+D+ S +T+ E
Sbjct: 5294 ---LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE 5328
Score = 46.6 bits (109), Expect = 1e-05
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Query: 35 LPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP K++K +S GS + L C + + + +WFK+ E++ K K
Sbjct: 4673 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHP-ISIQWFKDDQEISASEK---YKFSFHDN 4728
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+ L I++ DSG Y C +K G++ S ++T+ E
Sbjct: 4729 TAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 4766
Score = 46.2 bits (108), Expect = 2e-05
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +++K +GS +V+ C+ + WF GNE++ K Q
Sbjct: 7682 PSFTRKLKETNGLSGSSVVMECKVYGS-PPISVSWFHEGNEISSGRKYQTTLTDNT---C 7737
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L +N +DSG+Y C + G+D SA +T+ E
Sbjct: 7738 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE 7773
Score = 45.8 bits (107), Expect = 2e-05
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +KE++ +SA K+ L C+ + + W K+G +L ++ KI + +
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDED-RKVTVTWSKDGQKLP---PGKDYKICFEDKIA 3699
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L I A L DSG Y+C ++ G+ S SA +T+ E
Sbjct: 3700 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 3735
Score = 45.1 bits (105), Expect = 4e-05
Identities = 35/125 (28%), Positives = 52/125 (41%), Gaps = 5/125 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P ++E+K E S + L CE + W KN E+ K + +
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGT-PPFEVTWLKNNREIRSSKK---YTLTDRVSVF 5010
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTS 155
L I K +D+GEY C V ++ G+ S S + + E I + +T SSAT S
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKI-ENTTTVLKSSATFQS 5069
Query: 156 TTGTS 160
T S
Sbjct: 5070 TVAGS 5074
Score = 45.1 bits (105), Expect = 4e-05
Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Query: 36 PPR-LKEMKSQESAA-GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
PP+ +K++++ + A G + L C+ S ++ WF+N +EL+ K I
Sbjct: 6363 PPKFVKKLEASKVAKQGESIQLECKISGS-PEIKVSWFRNDSELHESWKYNMSFINSV-- 6419
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPA 141
+ L IN+AS DSG+Y+C+ + +G+ S S +T V++ + T P+
Sbjct: 6420 -ALLTINEASAEDSGDYICEAHNGVGDASCSTALT-VKAPPVFTQKPS 6465
Score = 44.7 bits (104), Expect = 5e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
Query: 52 KLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYM 111
++ L+CE S + + KWFK+G E+ K I+ + L+I KA L D GEY+
Sbjct: 11679 EITLKCEVSKD---VPVKWFKDGEEIVPSPK---YSIKADGLRRILKIKKADLKDKGEYV 11732
Query: 112 CKVISKLGNDSASANITI 129
C G D AN+T+
Sbjct: 11733 C----DCGTDKTKANVTV 11746
Score = 43.9 bits (102), Expect = 9e-05
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
++ WFKN EL+ N +++ ++ L I + DSG Y C+ ++ +G+DS S
Sbjct: 3767 IQVTWFKNNKELSESN---TVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCST 3823
Query: 126 NITIVESNEII 136
I I E I
Sbjct: 3824 EIVIKEPPSFI 3834
Score = 43.5 bits (101), Expect = 1e-04
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 17 ERGSGKKPESAAGSQSPALPPRLKEMKSQESAA-GSKLVLRCETSSEYSSLRFKWFKNGN 75
E +G S + + + PP + S A GS ++L+CE S W K+
Sbjct: 6438 EAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGT-PPFEVVWVKDRK 6496
Query: 76 ELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
++ K KI K + L I +D GEY CK +++G+D+ S ++ E
Sbjct: 6497 QVRNSKK---FKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE 6549
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
Query: 44 SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKAS 103
SQ G L C+ + ++ WF N E+ +K + ++ + LR+
Sbjct: 4308 SQLLKKGDATQLACKVTGT-PPIKITWFANDREIKESSKHRMSFVEST---AVLRLTDVG 4363
Query: 104 LADSGEYMCKVISKLGNDSASANITIVES 132
+ DSGEYMC+ ++ G+D S+ + + ES
Sbjct: 4364 IEDSGEYMCEAQNEAGSDHCSSIVIVKES 4392
Score = 42.0 bits (97), Expect = 3e-04
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 13/113 (11%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P ++++K + G+ +VL C S + + WF++GNE+ K Q+
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGS-APISVGWFQDGNEIVSGPKCQS---SFSENVC 6796
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE---------SNEIITGM 139
L ++ +D+G Y C + G+D SA +T+ E S E++ GM
Sbjct: 6797 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGM 6849
Score = 41.6 bits (96), Expect = 4e-04
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 10/154 (6%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+ PP ++ +K+ E + L CE S W+K+ +L K KI K
Sbjct: 5521 SFPPIVETLKNAEVS------LECELSGT-PPFEVVWYKDKRQLRSSKK---YKIASKNF 5570
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATS 153
+ + I +D GEY CK +++G+D+ + + E ++ + + T A +
Sbjct: 5571 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQ 5630
Query: 154 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSN 187
S G + KEK + E + + N
Sbjct: 5631 ASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN 5664
Score = 41.6 bits (96), Expect = 4e-04
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 31 QSPALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQ 89
Q LPP +++K E G + L C + + ++ W+++G L +N++
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS-APIQVCWYRDGVLLR---DDENLQTS 6224
Query: 90 KKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+ L+I + L+ SG+Y C + LG S+SA +T E
Sbjct: 6225 FVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 6266
Score = 41.6 bits (96), Expect = 4e-04
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P ++ ++ E+ G L+C+ +R W+K +L ++ P K+Q K +
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGT-PEIRISWYKEHTKL--RSAPA-YKMQFKNNVA 7075
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITI 129
L INK +D GEY CK + +G ++SA + I
Sbjct: 7076 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 7109
Score = 41.6 bits (96), Expect = 4e-04
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
+++ +S + G L C T + L KWFK+G EL NK + K G L+
Sbjct: 7589 VEKPESIKVTTGDTCTLEC-TVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG---LK 7644
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITI 129
I + +DSG Y +V + +G DS +A++ +
Sbjct: 7645 IINVAPSDSGVYSFEVQNPVGKDSCTASLQV 7675
Score = 41.2 bits (95), Expect = 6e-04
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
++ GS + PPR + S S K V T + WFK+ E+ R++
Sbjct: 7480 DTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRES--D 7537
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
NI I + L+ ++ A++G+Y C++ + G A ++++E I+
Sbjct: 7538 NIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 7589
Score = 41.2 bits (95), Expect = 6e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 9/117 (7%)
Query: 17 ERGSGKKPESAAGSQSPALPPR--LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNG 74
E SGK SA Q L P +K+++ + + G L+C+ + + W+K
Sbjct: 7943 ENASGKDSCSA---QILILEPPYFVKQLEPVKVSVGDSASLQCQLAGT-PEIGVSWYKGD 7998
Query: 75 NELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+L K+ + + L N+ + DSGEY+CK + +G SAS +T+ E
Sbjct: 7999 TKLRPTT---TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE 8052
Score = 41.2 bits (95), Expect = 6e-04
Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 8/117 (6%)
Query: 31 QSPALPPRLKEMKSQESAA-GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQ 89
+ P PP + + + + G + L C +R +W K G E+ ++
Sbjct: 8340 KEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGS-EPIRIQWLKAGREIKPSDR---CSFS 8395
Query: 90 KKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGA 146
G + L + + ADSG+Y+CK + G+D+ + +TI + + PA+ + A
Sbjct: 8396 FASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV---APATKKAA 8449
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
E AG PA P + + Q+ G +V C+ + W K+G L +
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVY-WKKSGVPLTTGYR-Y 1128
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
+ K+ G+ +L I+ D+GEY V +K G SASA++ E++ M + E
Sbjct: 1129 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL--MKSQQE 1186
Query: 145 GAYVSSATS 153
Y + T+
Sbjct: 1187 MLYQTQVTA 1195
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/128 (24%), Positives = 57/128 (44%), Gaps = 4/128 (3%)
Query: 36 PPR-LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGK 94
PPR +K++ + G + LR + + W K+ E+ R++ +N +I
Sbjct: 6550 PPRFVKKLSDTSTLIGDAVELRAIVEG-FQPISVVWLKDRGEVIRES--ENTRISFIDNI 6606
Query: 95 SELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATST 154
+ L++ ++SG+Y+C++ + G SA +T++E II T A
Sbjct: 6607 ATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALEC 6666
Query: 155 STTGTSHL 162
TGT L
Sbjct: 6667 VVTGTPEL 6674
Score = 40.4 bits (93), Expect = 0.001
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 11/111 (9%)
Query: 26 SAAGSQSPALPPRLKEMK-------SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELN 78
+AAGS S + ++KE E+ G+ + L CE W+K+ EL
Sbjct: 7382 NAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGT-PPFHVSWYKDKRELR 7440
Query: 79 RKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
K KI + + + I AD GEY CK + +G+D+ +I +
Sbjct: 7441 SGKK---YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIAL 7488
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 33 PALPPRLKE-MKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKK 91
P PP L +K+ G + L C S Y S W++ ++ + +I +
Sbjct: 939 PVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQIESSI---DFQITFQ 994
Query: 92 PGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
G + L I +A DSG + C +++ G S S + + S E A TE
Sbjct: 995 SGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE 1047
Score = 40.0 bits (92), Expect = 0.001
Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 30 SQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQ 89
++ P +L+ K ++ S+L + S E +R WF+N +EL +K + I
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPE---IRVVWFRNEHELPASDKYRMTFID 5476
Query: 90 KKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
+ +++N S DSG+++C+ + G+ S S + IV+ + + P E
Sbjct: 5477 SV---AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV-IVKEPPVFSSFPPIVE 5527
Score = 40.0 bits (92), Expect = 0.001
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSG 108
AG C + +R W K+ E+ N I LRI K DSG
Sbjct: 6284 AGESADFECHVTGA-QPMRITWSKDNKEIRPGG---NYTITCVGNTPHLRILKVGKGDSG 6339
Query: 109 EYMCKVISKLGNDSASANITIVESNEIITGMPAS 142
+Y C+ + +G D SA +++ E + + + AS
Sbjct: 6340 QYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEAS 6373
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
CE S E + + KWFK+G E+ + K I K L INK L D EY C+V +
Sbjct: 12395 CELSRE--NAKVKWFKDGAEIKKGKK---YDIISKGAVRILVINKCLLDDEAEYSCEVRT 12449
Query: 117 KLGNDSASANITIVESNEIITGMPASTE 144
S +T++E + T A+ E
Sbjct: 12450 A----RTSGMLTVLEEEAVFTKNLANIE 12473
Score = 38.9 bits (89), Expect = 0.003
Identities = 20/86 (23%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 46 ESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLA 105
++ G C + ++ W K+ E+ K Q ++ + L+++K
Sbjct: 8163 DAVVGESADFECHVTGT-QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKG--- 8218
Query: 106 DSGEYMCKVISKLGNDSASANITIVE 131
DSG+Y C ++++G DS +A + I E
Sbjct: 8219 DSGQYTCYAVNEVGKDSCTAQLNIKE 8244
Score = 38.5 bits (88), Expect = 0.004
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Query: 44 SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKAS 103
S++ GS + L+ T + L +WFK EL + I K+ +S L +
Sbjct: 4214 SKDVLPGSAVCLK-STFQGSTPLTIRWFKGNKELVSGG---SCYITKEALESSLELYLVK 4269
Query: 104 LADSGEYMCKVISKLGNDSASANITIVE 131
+DSG Y CKV + G SAN+ + E
Sbjct: 4270 TSDSGTYTCKVSNVAGGVECSANLFVKE 4297
Score = 38.5 bits (88), Expect = 0.004
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KWFK+G EL +K KI S L+I DSGEY +V + +G S A I
Sbjct: 4611 KWFKDGQELTLGSK---YKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARIN 4667
Query: 129 IVE 131
+++
Sbjct: 4668 VLD 4670
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 6/99 (6%)
Query: 33 PALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKP 92
P+ RL E + KL R S + W+KN E+ + N +I K
Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQP---ITVAWYKNNIEIQPTS---NCEITFKN 8302
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L++ KA + D+G Y CKV + G+ +++I I E
Sbjct: 8303 NTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 8341
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + E++ E+A G + L+C+ + + W+K +L + +
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGT-PEITVSWYKGDTKLR---PTPEYRTYFTNNVA 6134
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L NK ++ DSGEY CK + +G S+ I E
Sbjct: 6135 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQE 6170
Score = 37.4 bits (85), Expect = 0.008
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
KE K E ++L E + WFK+ N + R + IQ L+I
Sbjct: 4397 KEFKPIEVLKEYDVMLLAEVAGT-PPFEITWFKD-NTILRSGRKYKTFIQDH--LVSLQI 4452
Query: 100 NKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
K AD+GEY C+V +++G+ SA +T+ E I
Sbjct: 4453 LKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFI 4489
Score = 37.4 bits (85), Expect = 0.008
Identities = 16/60 (26%), Positives = 28/60 (46%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W+K+G ++ + + + G +L IN + D EY +K G DS A +T+
Sbjct: 31723 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 37.4 bits (85), Expect = 0.008
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK---WFKNGNELNRKNKPQNIKIQKKP 92
PP++ + E+ SK + + E S LR K W+K+G +L Q
Sbjct: 32717 PPKITQFLKAEA---SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFH--YSAD 32771
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSAS 124
G EL+IN + +D GEY+C++ + G +
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTN 32803
Score = 36.6 bits (83), Expect = 0.014
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 8/120 (6%)
Query: 23 KPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLR------FKWFKNGNE 76
K ++ GS + +LKE S S V+ E + +S+ +W K E
Sbjct: 5590 KAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649
Query: 77 LNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
+ R++ +NI+I + L+ KA A++G+Y+C++ + G A + ++E I+
Sbjct: 5650 VIRES--ENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIV 5707
Score = 36.6 bits (83), Expect = 0.014
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 14 KKKERGSG--KKPESAAGS-QSPALPPR-LKEMK----SQESAAGSKLVLRCETSSEYSS 65
+K GSG K P+ A + Q A+P + +KE+K ++ GS + C S S+
Sbjct: 11089 RKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP--ST 11146
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
W K+G+ + K + I K +L I L+D+GEY C + +LGN ++
Sbjct: 11147 AITTWMKDGSNIRESPKHRFIADGKD---RKLHIIDVQLSDAGEYTC--VLRLGNKEKTS 11201
Query: 126 NITIV 130
+V
Sbjct: 11202 TAKLV 11206
Score = 36.2 bits (82), Expect = 0.018
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G + + K K+ + G L I+K +DSG Y C V + G+ S+S +TI
Sbjct: 32885 WTKDGKAITQGGK---YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 32941
Score = 35.4 bits (80), Expect = 0.031
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 50 GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGE 109
G+ L C + L KWFK+G EL+ +K I K + L+I A ++D G
Sbjct: 6659 GNPFALECVVTGT-PELSAKWFKDGRELSADSKHHITFINK---VASLKIPCAEMSDKGL 6714
Query: 110 YMCKVISKLGNDSASANITI 129
Y +V + +G + + ++ +
Sbjct: 6715 YSFEVKNSVGKSNCTVSVHV 6734
Score = 35.4 bits (80), Expect = 0.031
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNK 82
K ++ Q G+ VL CE S E + + KWFKNG E+ + K
Sbjct: 12289 KPLEDQTVEEGATAVLECEVSRE--NAKVKWFKNGTEILKSKK 12329
Score = 35.0 bits (79), Expect = 0.040
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +K ++ + G+ +L+CE S WFK+ ++ R +K + QK
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGT-GPFEISWFKDKKQI-RSSKKYRLFSQKS--LV 3886
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L I + AD GEY C V +++G A + E
Sbjct: 3887 CLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE 3922
Score = 35.0 bits (79), Expect = 0.040
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
+K + G L+L T + + W KNG + Q I + L
Sbjct: 7871 VKRLNDYSIEKGKPLILE-GTFTGTPPISVTWKKNGINVTPS---QRCNITTTEKSAILE 7926
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVE 131
I +++ D+G+Y C + + G DS SA I I+E
Sbjct: 7927 IPSSTVEDAGQYNCYIENASGKDSCSAQILILE 7959
Score = 34.7 bits (78), Expect = 0.052
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 34 ALPPR-LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKP 92
A PP L KS + G C T + + W K+G L+ N +I
Sbjct: 3548 AYPPTFLSRPKSLTTFVGKAAKFIC-TVTGTPVIETIWQKDGAALSPS---PNWRISDAE 3603
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
K L ++ ++ D G Y CK +K G D A + I++ I
Sbjct: 3604 NKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFI 3647
Score = 34.7 bits (78), Expect = 0.052
Identities = 22/101 (21%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +++ +SQ+ +++ L+ + + KWFK+ EL+ + K +
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGT-APMTIKWFKDNKELHSGAARS---VWKDDTST 4823
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
L + A DSG Y+C++ + +G ++ A + + E + I
Sbjct: 4824 SLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFI 4864
Score = 34.7 bits (78), Expect = 0.052
Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 4/99 (4%)
Query: 44 SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKAS 103
S + A G +C + + ++ W K+ E+ N K+ + L + K
Sbjct: 7220 SVDLALGESGTFKCHVTGT-APIKITWAKDNREIRPGG---NYKMTLVENTATLTVLKVG 7275
Query: 104 LADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAS 142
D+G+Y C + G DS SA + + E I + S
Sbjct: 7276 KGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPS 7314
Score = 34.7 bits (78), Expect = 0.052
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G E+ ++ + ++ + L + K+ AD+G Y + +KLG+ +AS N+ +
Sbjct: 14420 WHKDGKEVKASDR---LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Query: 130 VESNEIITGMPASTEGAYVSSATSTS 155
+ G+P + S T +S
Sbjct: 14477 I-------GLPGPCKDIKASDITKSS 14495
Score = 34.7 bits (78), Expect = 0.052
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNI-KIQKKPGKSELRINKASLADS 107
AG +VL + + W K G ++ +P +I +I P S L I A+ D+
Sbjct: 20392 AGDTIVLNAISILGKPLPKSSWSKAGKDI----RPSDITQITSTPTSSMLTIKYATRKDA 20447
Query: 108 GEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTST 156
GEY + G +T+++ + G P E + VS+ +T T
Sbjct: 20448 GEYTITATNPFGTKVEHVKVTVLD----VPGPPGPVEISNVSAEKATLT 20492
Score = 34.3 bits (77), Expect = 0.068
Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 4/110 (3%)
Query: 50 GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGE 109
G C+ + +R W+ +GNE+ K I G + +I+ A + +SG
Sbjct: 4876 GQSTTFECQITGT-PKIRVSWYLDGNEITAIQKHG---ISFIDGLATFQISGARVENSGT 4931
Query: 110 YMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGT 159
Y+C+ + G S S + + E I + Y TGT
Sbjct: 4932 YVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGT 4981
Score = 34.3 bits (77), Expect = 0.068
Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 34 ALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKP 92
A+PP + +K+ G+ +L C+ + S + WF ++ K Q
Sbjct: 5797 AVPPSFTRRLKNTGGVLGASCILECKVAGS-SPISVAWFHEKTKIVSGAKYQTTF---SD 5852
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L++N +D G Y C + G+D A +T+ E
Sbjct: 5853 NVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 5891
Score = 34.3 bits (77), Expect = 0.068
Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
C+ + S + W+ +L K +I + G + L + + D G Y CKV++
Sbjct: 31589 CKIENYDQSTQVTWYFGVRQLENSEK---YEITYEDGVAILYVKDITKLDDGTYRCKVVN 31645
Query: 117 KLGNDSASANITIVESNEI 135
G DS+ A + + E+
Sbjct: 31646 DYGEDSSYAELFVKGVREV 31664
Score = 33.5 bits (75), Expect = 0.12
Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 67 RFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASAN 126
+ KWFK+ EL K I + S L + + +G+Y C V + +G+DS +
Sbjct: 5360 KIKWFKDDVELVSGPK---CFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTM 5416
Query: 127 ITIVESNEIITGMPAS 142
+ + E + + + AS
Sbjct: 5417 LLVTEPPKFVKKLEAS 5432
Score = 33.5 bits (75), Expect = 0.12
Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 13/112 (11%)
Query: 67 RFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASAN 126
+ KWFK EL ++ I + +EL + + +SG+Y C V + G+ S + +
Sbjct: 6864 KVKWFKGSRELV---PGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 6920
Query: 127 ITIVESNEII---------TGMPASTEGAYVSS-ATSTSTTGTSHLVKCAEK 168
+ + E + TG P E Y + S S +L+ +E+
Sbjct: 6921 LFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSER 6972
Score = 32.7 bits (73), Expect = 0.20
Identities = 15/66 (22%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
++ W+K+ E+ +K ++ + L ++ S+ DSG+Y C+ + G+ S+S
Sbjct: 7335 IKVLWYKDETEIQESSK---FRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Query: 126 NITIVE 131
++ + E
Sbjct: 7392 SLKVKE 7397
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK+ + +E ++V CE ++E + KWF+N + +K I +K LR
Sbjct: 12646 LKDTRVKEQ---QEVVFNCEVNTE--GAKAKWFRNEEAIFDSSK---YIILQKDLVYTLR 12697
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEI 135
I A L D Y + + G + SA IVE ++
Sbjct: 12698 IRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDL 12734
Score = 32.7 bits (73), Expect = 0.20
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
++ ++ Q V C+ S E +++ KW++NG E+ K K +K L
Sbjct: 12826 VEHLEDQTVTEFDDAVFSCQLSREKANV--KWYRNGREIKEGKK---YKFEKDGSIHRLI 12880
Query: 99 INKASLADSGEYMCKV 114
I L D EY C V
Sbjct: 12881 IKDCRLDDECEYACGV 12896
Score = 32.3 bits (72), Expect = 0.26
Identities = 24/124 (19%), Positives = 48/124 (38%), Gaps = 4/124 (3%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK + G ++L T + + W K+G + K + +K L
Sbjct: 5989 LKRLSDHSVEPGKSIILE-STYTGTLPISVTWKKDGFNITTSEKCNIVTTEKT---CILE 6044
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTSTTG 158
I ++ D+G+Y C++ ++ G D A ++ +E +T + S + G
Sbjct: 6045 ILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAG 6104
Query: 159 TSHL 162
T +
Sbjct: 6105 TPEI 6108
Score = 32.0 bits (71), Expect = 0.34
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K + Q A + V CE ++ S + +W ++G L N NI+ + K L I
Sbjct: 2624 KPLTDQTVAESQEAVFECEVANPDS--KGEWLRDGKHLPLTN---NIRSESDGHKRRLII 2678
Query: 100 NKASLADSGEYMCKV 114
L D GEY KV
Sbjct: 2679 AATKLDDIGEYTYKV 2693
Score = 31.6 bits (70), Expect = 0.44
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E K + E + Y + +KW KNG E+ +K Q ++ K L
Sbjct: 2975 LKDINAEE-----KDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQ---MRTKKLTHSLN 3026
Query: 99 INKASLADSGEY 110
I D+ +Y
Sbjct: 3027 IRNVHFGDAADY 3038
Score = 30.4 bits (67), Expect = 0.99
Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 3/68 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+W +G L N+ +++ + G L A DSG C+ +K G D SA +
Sbjct: 1737 EWLHDGKPLEAANR---LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Query: 129 IVESNEII 136
+ + ++
Sbjct: 1794 VKDEKSLV 1801
Score = 30.0 bits (66), Expect = 1.3
Identities = 16/65 (24%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASAN 126
+ WF+ EL + ++ I + +EL + ++ SGEY C V + G S +
Sbjct: 5923 KVNWFRGARELVKGDR---CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTR 5979
Query: 127 ITIVE 131
+ + E
Sbjct: 5980 LFVKE 5984
Score = 30.0 bits (66), Expect = 1.3
Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 12/90 (13%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WFK +EL ++ + + +EL + + SGEY C V ++ G S + ++ I
Sbjct: 7808 WFKGSSELVPGDR---CNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI 7864
Query: 130 ---------VESNEIITGMPASTEGAYVSS 150
+ I G P EG + +
Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGT 7894
Score = 30.0 bits (66), Expect = 1.3
Identities = 22/100 (22%), Positives = 47/100 (47%), Gaps = 12/100 (12%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E + V E S + ++R KWFKN L + +++ +Q + +
Sbjct: 11935 LKDVTAKEKESA---VFTVELS--HDNIRVKWFKNDQRL---HTTRSVSMQDEGKTHSIT 11986
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG 138
S+ D+ + + + S+ A +T++E + TG
Sbjct: 11987 FKDLSIDDTSQIRVEAMGM----SSEAKLTVLEGDPYFTG 12022
Score = 29.6 bits (65), Expect = 1.7
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Query: 50 GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGE 109
G L C+ + L +W+K+G L K + K S LRI D+G
Sbjct: 5718 GETCTLECKVAGT-PELSVEWYKDGKLLTSSQKHKFSFYNKI---SSLRILSVERQDAGT 5773
Query: 110 YMCKVISKLGNDSASANITI 129
Y +V + +G S +A + +
Sbjct: 5774 YTFQVQNNVGKSSCTAVVDV 5793
Score = 29.6 bits (65), Expect = 1.7
Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW K + + N+ + I +K +++L I + DSG Y C ++ G ++ N+
Sbjct: 8486 KWTKG--KWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 8543
Query: 129 IVE 131
+ E
Sbjct: 8544 VDE 8546
Score = 29.6 bits (65), Expect = 1.7
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+ + + P+ +KI + S+ + KA +D G+Y+ + G+ A A + +
Sbjct: 18235 WTKDKDATDLTRSPR-VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Query: 130 VE 131
++
Sbjct: 18294 LD 18295
Score = 29.6 bits (65), Expect = 1.7
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 35 LPPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP+++ + S S G L + C + E + W G +++ + + + I+
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGRKIHSQEQGR-FHIENTDD 33384
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L I D G Y + ++ G+DSA+ NI I
Sbjct: 33385 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 29.3 bits (64), Expect = 2.2
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +K + + + CE S + +W K+ EL ++ IKIQK+ L I
Sbjct: 3062 KHIKDIKVLEKKRAMFECEVSEP--DITVQWMKDDQELQITDR---IKIQKEKYVHRLLI 3116
Query: 100 NKASLADSGEY 110
++D+G+Y
Sbjct: 3117 PSTRMSDAGKY 3127
Score = 28.5 bits (62), Expect = 3.7
Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 9/116 (7%)
Query: 24 PESAAGSQS-PALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
PE + Q P PP + ++ ++ G +C S + L+ W+ ++K
Sbjct: 3331 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKVSWYSK----DKKI 3384
Query: 82 KPQNI-KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
KP ++ + +L I +A D G Y + +G S++AN+++ I+
Sbjct: 3385 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESIL 3440
Score = 28.5 bits (62), Expect = 3.7
Identities = 18/96 (18%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +K+++S S G + + W K+ +E+ + NI++ + +
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLP-ITVTWLKDSDEITEDD---NIRMTFENNVA 4541
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L ++ + G+Y+C+ + G SA +++ E
Sbjct: 4542 SLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 4577
Score = 28.5 bits (62), Expect = 3.7
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSP--ALPP----------RLKEMKSQESAAGSKLVLRC 57
KG + KE + E+AAG P A PP ++ S E G ++ L
Sbjct: 14642 KGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 14701
Query: 58 ETS-SEYSSLRFKWFKNGN-----ELNRKNKP--------------------QNIKIQK- 90
S S Y ++ W K+ N E+ ++ P Q + I
Sbjct: 14702 SISGSPYPTIT--WIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNS 14759
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
K G+S+LR+ + D G YM KV + G A ++++++
Sbjct: 14760 KKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT 14801
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNI---KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSA 123
+ +W KN + + I ++ + K+EL I KA D G Y ++LG+
Sbjct: 15429 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 15488
Query: 124 SANITIVE 131
+ ++ + +
Sbjct: 15489 NVHVEVYD 15496
Score = 28.5 bits (62), Expect = 3.7
Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
++ E ++ LPP++ + AG KL + + KW K +E+ +
Sbjct: 18885 REAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPT-CKWKKGEDEVVTSS 18943
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
++ + K S L I + DSG Y + G D+ + ++++
Sbjct: 18944 ---HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 18991
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/69 (21%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF G++L + + ++ ++L I + ++ D+GEY ++ + G S + + I
Sbjct: 29772 WFFAGSKLRESER---VTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 29828
Query: 130 VESNEIITG 138
++ TG
Sbjct: 29829 LDKPGPPTG 29837
Score = 28.1 bits (61), Expect = 4.9
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF +G ++ N + + K+ G L I A+ +DSGE+ ++ G S S +T+
Sbjct: 1490 WFHDGQQI--VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW +G+E+ ++ ++ S L I D+GEY V + G+ + + ++T
Sbjct: 17543 KWTTDGSEIKTD---EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 17599
Query: 129 IVE 131
+++
Sbjct: 17600 VLD 17602
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W + E K ++I+K ++L I+ D+G+Y+ K+ + G+ SA + +
Sbjct: 24058 WSREEGEFTDK-----VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 24112
Query: 130 VES 132
+++
Sbjct: 24113 LDT 24115
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVI 115
CETS + ++ KW+K+G E++ +K + +K S L I+ +D+ +Y C ++
Sbjct: 2196 CETSEPF--VKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTID---TSDAEDYSCVLV 2249
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K EL++ + I KSEL I A D G Y+ + G+ A+A + +
Sbjct: 15138 WTKEEGELDK----DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 15193
Query: 130 VE 131
+
Sbjct: 15194 FD 15195
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 51.6 bits (122), Expect = 4e-07
Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E K G K L+CE S+ S F+W+K+ L K +K++ +P S
Sbjct: 222 PPYISEAKGTGVPVGQKGTLQCEASA-VPSAEFQWYKDDKRLIEGKK--GVKVENRPFLS 278
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTS 155
+L S D G Y C +KLG+ +AS + V++ + P G A S
Sbjct: 279 KLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFEVKTTAL---TPWKGPG-----AVSEV 330
Query: 156 TTGTSHLVKC 165
+ GTS C
Sbjct: 331 SNGTSRRAGC 340
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 51.2 bits (121), Expect = 5e-07
Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 15/147 (10%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP E S A G L L+C + + + W K G L +++
Sbjct: 2827 PPIRIEPSSSRVAEGQTLDLKCVVPGQ-AHAQVTWHKRGGNLPARHQVHG---------P 2876
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTS 155
LR+N+ S ADSGEY C+V G AS +TI S+ P + Y+ +++S
Sbjct: 2877 LLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHV 2936
Query: 156 TTGTSHLVKC-----AEKEKTFCVNGG 177
T G + + C A + T+ GG
Sbjct: 2937 TEGQTLDLNCVVPGQAHAQVTWYKRGG 2963
Score = 48.1 bits (113), Expect = 5e-06
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 30 SQSPALPPRLK-EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKI 88
S S A PP +K E S G L L C + + + W++ G L P + ++
Sbjct: 2044 SASDASPPPVKIESSSPSVTEGQTLDLNCVVAGS-AHAQVTWYRRGGSL-----PPHTQV 2097
Query: 89 QKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIV---ESNEIITGMPASTEG 145
S LR+ + S ADSGEY+C+V + G AS ++++ S T +P ST
Sbjct: 2098 HG----SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRP 2153
Query: 146 AYVSSATSTSTTGTSHLVKC 165
+ ++S G + + C
Sbjct: 2154 IRIEPSSSHVAEGQTLDLNC 2173
Score = 46.6 bits (109), Expect = 1e-05
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 13/140 (9%)
Query: 26 SAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQN 85
S + SQ A P R+ E S A G L L C +S+ + W+K G L +++
Sbjct: 2525 SGSHSQGVAYPVRI-ESSSASLANGHTLDLNCLVASQ-APHTITWYKRGGSLPSRHQIVG 2582
Query: 86 IKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEG 145
S LRI + + ADSGEY+C V + G+ S +TI S + +P+ +
Sbjct: 2583 ---------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS--SHVPSVSPP 2631
Query: 146 AYVSSATSTSTTGTSHLVKC 165
+ S++ T G + + C
Sbjct: 2632 IRIESSSPTVVEGQTLDLNC 2651
Score = 46.6 bits (109), Expect = 1e-05
Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 14/118 (11%)
Query: 27 AAGSQSP---ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKP 83
+AGS S ++P R+ E S A G L L C + + + W K G L ++
Sbjct: 2716 SAGSPSAPGSSMPIRI-ESSSSHVAEGETLDLNCVVPGQ-AHAQVTWHKRGGSLPSHHQT 2773
Query: 84 QNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPA 141
+ S LR++ S ADSGEY+C+V+ G AS +TI S +PA
Sbjct: 2774 RG---------SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 2822
Score = 45.4 bits (106), Expect = 3e-05
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 21/142 (14%)
Query: 25 ESAAGSQSPALPPRLK-EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKP 83
+ + S P++ P ++ E S G L L C + + ++ W+K G L +++
Sbjct: 2618 QGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAI-ITWYKRGGSLPSRHQT 2676
Query: 84 QNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMP-AS 142
S LR+++ S+ADSGEY+C+ A+ NI +E++ +I+ P A
Sbjct: 2677 HG---------SHLRLHQMSVADSGEYVCR---------ANNNIDALEASIVISVSPSAG 2718
Query: 143 TEGAYVSSATSTSTTGTSHLVK 164
+ A SS + +SH+ +
Sbjct: 2719 SPSAPGSSMPIRIESSSSHVAE 2740
Score = 44.3 bits (103), Expect = 7e-05
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 41 EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRIN 100
E S + A G L L C + + + + W K G L +++ S LR+
Sbjct: 2442 ESSSSQVAEGQTLDLNCLVAGQ-AHAQVTWHKRGGSLPARHQVHG---------SRLRLL 2491
Query: 101 KASLADSGEYMCKVISKLGNDSASANITI 129
+ + ADSGEY+C+V+ G AS +TI
Sbjct: 2492 QVTPADSGEYVCRVVGSSGTQEASVLVTI 2520
Score = 42.7 bits (99), Expect = 2e-04
Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 20/142 (14%)
Query: 41 EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRIN 100
E S A G L L C + + + W K G L +++ S LR++
Sbjct: 2157 EPSSSHVAEGQTLDLNCVVPGQ-AHAQVTWHKRGGSLPARHQTHG---------SLLRLH 2206
Query: 101 KASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTS 160
+ + ADSGEY+C V+ G AS +TI S +P + S++ST G +
Sbjct: 2207 QVTPADSGEYVCHVVGTSGPLEASVLVTIEAS-----VIPGPIPPVRIESSSSTVAEGQT 2261
Query: 161 HLVKC-----AEKEKTFCVNGG 177
+ C A + T+ GG
Sbjct: 2262 LDLSCVVAGQAHAQVTWYKRGG 2283
Score = 40.8 bits (94), Expect = 7e-04
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 12/112 (10%)
Query: 23 KPESAAGSQSPALP-PRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
+P S +P L P E S G L L C + + + W+K G L ++
Sbjct: 2911 EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQ-AHAQVTWYKRGGSLPARH 2969
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLG-NDSASANITIVES 132
+ S+LR++ S ADSGEY+C+ S G AS +T+ S
Sbjct: 2970 QTHG---------SQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPS 3012
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 14/132 (10%)
Query: 35 LPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGK 94
+PP E S A G L L C + + + + W+K G L +++ +
Sbjct: 2244 IPPVRIESSSSTVAEGQTLDLSCVVAGQ-AHAQVTWYKRGGSLPARHQVRG--------- 2293
Query: 95 SELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPA-STEGAYVSSATS 153
S L I +AS AD+G+Y+C+ + + AS +T+ + PA ST+ + ++S
Sbjct: 2294 SRLYIFQASPADAGQYVCRASNGM---EASITVTVTGTQGANLAYPAGSTQPIRIEPSSS 2350
Query: 154 TSTTGTSHLVKC 165
G + + C
Sbjct: 2351 QVAEGQTLDLNC 2362
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 10/95 (10%)
Query: 41 EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRIN 100
E S + A G L L C + S + W K G L +++ S LR+
Sbjct: 2346 EPSSSQVAEGQTLDLNCVVPGQ-SHAQVTWHKRGGSLPVRHQTHG---------SLLRLY 2395
Query: 101 KASLADSGEYMCKVISKLGNDSASANITIVESNEI 135
+AS ADSGEY+C+V+ AS +TI + +
Sbjct: 2396 QASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSV 2430
Score = 37.7 bits (86), Expect = 0.006
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 15/139 (10%)
Query: 31 QSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQK 90
+SP + E S + AG + L+C L F+W + G+ L + +N
Sbjct: 3296 ESPPYATTVPEHASVQ--AGETVQLQCLAHGT-PPLTFQWSRVGSSLPGRATARN----- 3347
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI--VESNEIITGMPA-STEGAY 147
L +A+ DSG Y C+V +K+G+ A A + + + T +PA ST
Sbjct: 3348 ----ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ 3403
Query: 148 VSSATSTSTTGTSHLVKCA 166
V+ T + G S CA
Sbjct: 3404 VTPQLETKSIGASVEFHCA 3422
Score = 33.1 bits (74), Expect = 0.15
Identities = 23/107 (21%), Positives = 42/107 (39%), Gaps = 10/107 (9%)
Query: 45 QESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASL 104
+ + G+ + C S+ + + +WFK G +L + Q+ LRI
Sbjct: 3409 ETKSIGASVEFHCAVPSDRGT-QLRWFKEGGQLPPGHSVQD---------GVLRIQNLDQ 3458
Query: 105 ADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSA 151
+ G Y+C+ G ASA + I ++ + S + V A
Sbjct: 3459 SCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3505
Score = 30.4 bits (67), Expect = 0.99
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 13/117 (11%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSG 108
AG + L C + S W K G L + + + I + L I + AD+G
Sbjct: 1969 AGRTVRLYCRAAG-VPSATITWRKEGGSLPPQARSERTDI------ATLLIPAITTADAG 2021
Query: 109 EYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKC 165
Y+C S G +A A I +V +++ AS + S++ + T G + + C
Sbjct: 2022 FYLCVATSPAG--TAQARIQVV----VLSASDASPPPVKIESSSPSVTEGQTLDLNC 2072
Score = 29.3 bits (64), Expect = 2.2
Identities = 28/112 (25%), Positives = 44/112 (39%), Gaps = 11/112 (9%)
Query: 29 GSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKI 88
G+ +P P E AG LRC + + W K + L +++ +
Sbjct: 3205 GAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPT-IHWSKLRSPLPWQHRLEG--- 3260
Query: 89 QKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMP 140
L I + + DSG+Y+C S G+ A+ I VES T +P
Sbjct: 3261 ------DTLIIPRVAQQDSGQYICNATSPAGHAEATI-ILHVESPPYATTVP 3305
Score = 27.3 bits (59), Expect = 8.4
Identities = 23/110 (20%), Positives = 43/110 (39%), Gaps = 14/110 (12%)
Query: 30 SQSPALP--PRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFK--NGNELNRKNKPQN 85
+++P+ P ++E +SQ G+ + C S+ + W + NG R
Sbjct: 1764 TEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNG 1823
Query: 86 IKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEI 135
I L I L+D+G Y+C + D +A + + S +
Sbjct: 1824 I----------LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTL 1863
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 50.8 bits (120), Expect = 7e-07
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 4/89 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E KS E+ G + L+CE S+ + F+W+++ +N N ++I+ G+S
Sbjct: 218 PPTITESKSNEATTGRQASLKCEASA-VPAPDFEWYRDDTRINSAN---GLEIKSTEGQS 273
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSAS 124
L + + G Y C +KLG +AS
Sbjct: 274 SLTVTNVTEEHYGNYTCVAANKLGVTNAS 302
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 50.4 bits (119), Expect = 9e-07
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E K G K L+CE S+ S F+W+K+ L K +K++ +P S
Sbjct: 222 PPYISEAKGTGVPVGQKGTLQCEASA-VPSAEFQWYKDDKRLIEGKK--GVKVENRPFLS 278
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSAS 124
+L S D G Y C +KLG+ +AS
Sbjct: 279 KLIFFNVSEHDYGNYTCVASNKLGHTNAS 307
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 50.4 bits (119), Expect = 9e-07
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 20 SGKKPESAAGSQSPALPPRLK-EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELN 78
SGK SA + P +K +++ E A G CE S ++RF+WFK G E+
Sbjct: 4512 SGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIY 4570
Query: 79 RKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+K I+ S L I + + D GEY CK ++ G+ S +A +T+
Sbjct: 4571 ESDK---CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 11/129 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + + +SQ G ++ CE S E S +WFKN ++ + N+ I +
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISS---NVSISRSRNVY 26884
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIV-----ESNEII--TGMPASTEGAYV 148
L I AS++DSG+Y K + G SA+A++ ++ S E++ T S +G++
Sbjct: 26885 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 26944
Query: 149 SSATSTSTT 157
S + S +
Sbjct: 26945 SQSVQMSAS 26953
Score = 44.7 bits (104), Expect = 5e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
Query: 52 KLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYM 111
++ L+CE S + + KWFK+G E+ K I+ + L+I KA L D GEY+
Sbjct: 5374 EITLKCEVSKD---VPVKWFKDGEEIVPSPK---YSIKADGLRRILKIKKADLKDKGEYV 5427
Query: 112 CKVISKLGNDSASANITI 129
C G D AN+T+
Sbjct: 5428 C----DCGTDKTKANVTV 5441
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
E AG PA P + + Q+ G +V C+ + W K+G L +
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVY-WKKSGVPLTTGYR-Y 1082
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
+ K+ G+ +L I+ D+GEY V +K G SASA++ E++ M + E
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL--MKSQQE 1140
Query: 145 GAYVSSATS 153
Y + T+
Sbjct: 1141 MLYQTQVTA 1149
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 33 PALPPRLKE-MKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKK 91
P PP L +K+ G + L C S Y S W++ ++ + +I +
Sbjct: 893 PVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQIESSI---DFQITFQ 948
Query: 92 PGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
G + L I +A DSG + C +++ G S S + + S E A TE
Sbjct: 949 SGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE 1001
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/135 (23%), Positives = 49/135 (36%), Gaps = 3/135 (2%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK 69
KG+G K +S P P LKE+K A G + E +
Sbjct: 3741 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT-VT 3799
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WFK +L I G +N DSG Y+CK + LG + +A + +
Sbjct: 3800 WFKENKQLC--TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Query: 130 VESNEIITGMPASTE 144
+ + +T P +
Sbjct: 3858 LLEDTDMTDTPCKAK 3872
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
CE S E + + KWFK+G E+ + K I K L INK L D EY C+V +
Sbjct: 6090 CELSRE--NAKVKWFKDGAEIKKGKK---YDIISKGAVRILVINKCLLDDEAEYSCEVRT 6144
Query: 117 KLGNDSASANITIVESNEIITGMPASTE 144
S +T++E + T A+ E
Sbjct: 6145 A----RTSGMLTVLEEEAVFTKNLANIE 6168
Score = 37.4 bits (85), Expect = 0.008
Identities = 16/60 (26%), Positives = 28/60 (46%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W+K+G ++ + + + G +L IN + D EY +K G DS A +T+
Sbjct: 25418 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 37.4 bits (85), Expect = 0.008
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK---WFKNGNELNRKNKPQNIKIQKKP 92
PP++ + E+ SK + + E S LR K W+K+G +L Q
Sbjct: 26412 PPKITQFLKAEA---SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFH--YSAD 26466
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSAS 124
G EL+IN + +D GEY+C++ + G +
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTN 26498
Score = 36.6 bits (83), Expect = 0.014
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 14 KKKERGSG--KKPESAAGS-QSPALPPR-LKEMK----SQESAAGSKLVLRCETSSEYSS 65
+K GSG K P+ A + Q A+P + +KE+K ++ GS + C S S+
Sbjct: 4784 RKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP--ST 4841
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
W K+G+ + K + I K +L I L+D+GEY C + +LGN ++
Sbjct: 4842 AITTWMKDGSNIRESPKHRFIADGKD---RKLHIIDVQLSDAGEYTC--VLRLGNKEKTS 4896
Query: 126 NITIV 130
+V
Sbjct: 4897 TAKLV 4901
Score = 36.2 bits (82), Expect = 0.018
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G + + K K+ + G L I+K +DSG Y C V + G+ S+S +TI
Sbjct: 26580 WTKDGKAITQGGK---YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26636
Score = 35.4 bits (80), Expect = 0.031
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNK 82
K ++ Q G+ VL CE S E + + KWFKNG E+ + K
Sbjct: 5984 KPLEDQTVEEGATAVLECEVSRE--NAKVKWFKNGTEILKSKK 6024
Score = 34.7 bits (78), Expect = 0.052
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G E+ ++ + ++ + L + K+ AD+G Y + +KLG+ +AS N+ +
Sbjct: 8115 WHKDGKEVKASDR---LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Query: 130 VESNEIITGMPASTEGAYVSSATSTS 155
+ G+P + S T +S
Sbjct: 8172 I-------GLPGPCKDIKASDITKSS 8190
Score = 34.7 bits (78), Expect = 0.052
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNI-KIQKKPGKSELRINKASLADS 107
AG +VL + + W K G ++ +P +I +I P S L I A+ D+
Sbjct: 14087 AGDTIVLNAISILGKPLPKSSWSKAGKDI----RPSDITQITSTPTSSMLTIKYATRKDA 14142
Query: 108 GEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTST 156
GEY + G +T+++ + G P E + VS+ +T T
Sbjct: 14143 GEYTITATNPFGTKVEHVKVTVLD----VPGPPGPVEISNVSAEKATLT 14187
Score = 34.3 bits (77), Expect = 0.068
Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
C+ + S + W+ +L K +I + G + L + + D G Y CKV++
Sbjct: 25284 CKIENYDQSTQVTWYFGVRQLENSEK---YEITYEDGVAILYVKDITKLDDGTYRCKVVN 25340
Query: 117 KLGNDSASANITIVESNEI 135
G DS+ A + + E+
Sbjct: 25341 DYGEDSSYAELFVKGVREV 25359
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK+ + +E ++V CE ++E + KWF+N + +K I +K LR
Sbjct: 6341 LKDTRVKEQ---QEVVFNCEVNTE--GAKAKWFRNEEAIFDSSK---YIILQKDLVYTLR 6392
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEI 135
I A L D Y + + G + SA IVE ++
Sbjct: 6393 IRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDL 6429
Score = 32.7 bits (73), Expect = 0.20
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
++ ++ Q V C+ S E +++ KW++NG E+ K K +K L
Sbjct: 6521 VEHLEDQTVTEFDDAVFSCQLSREKANV--KWYRNGREIKEGKK---YKFEKDGSIHRLI 6575
Query: 99 INKASLADSGEYMCKV 114
I L D EY C V
Sbjct: 6576 IKDCRLDDECEYACGV 6591
Score = 32.0 bits (71), Expect = 0.34
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K + Q A + V CE ++ S + +W ++G L N NI+ + K L I
Sbjct: 2578 KPLTDQTVAESQEAVFECEVANPDS--KGEWLRDGKHLPLTN---NIRSESDGHKRRLII 2632
Query: 100 NKASLADSGEYMCKV 114
L D GEY KV
Sbjct: 2633 AATKLDDIGEYTYKV 2647
Score = 31.6 bits (70), Expect = 0.44
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E K + E + Y + +KW KNG E+ +K Q ++ K L
Sbjct: 2929 LKDINAEE-----KDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQ---MRTKKLTHSLN 2980
Query: 99 INKASLADSGEY 110
I D+ +Y
Sbjct: 2981 IRNVHFGDAADY 2992
Score = 30.4 bits (67), Expect = 0.99
Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 3/68 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+W +G L N+ +++ + G L A DSG C+ +K G D SA +
Sbjct: 1691 EWLHDGKPLEAANR---LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Query: 129 IVESNEII 136
+ + ++
Sbjct: 1748 VKDEKSLV 1755
Score = 30.0 bits (66), Expect = 1.3
Identities = 22/100 (22%), Positives = 47/100 (47%), Gaps = 12/100 (12%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E + V E S + ++R KWFKN L + +++ +Q + +
Sbjct: 5630 LKDVTAKEKESA---VFTVELS--HDNIRVKWFKNDQRL---HTTRSVSMQDEGKTHSIT 5681
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG 138
S+ D+ + + + S+ A +T++E + TG
Sbjct: 5682 FKDLSIDDTSQIRVEAMGM----SSEAKLTVLEGDPYFTG 5717
Score = 29.6 bits (65), Expect = 1.7
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+ + + P+ +KI + S+ + KA +D G+Y+ + G+ A A + +
Sbjct: 11930 WTKDKDATDLTRSPR-VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Query: 130 VE 131
++
Sbjct: 11989 LD 11990
Score = 29.6 bits (65), Expect = 1.7
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 35 LPPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP+++ + S S G L + C + E + W G +++ + + + I+
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGRKIHSQEQGR-FHIENTDD 27079
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L I D G Y + ++ G+DSA+ NI I
Sbjct: 27080 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 29.3 bits (64), Expect = 2.2
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +K + + + CE S + +W K+ EL ++ IKIQK+ L I
Sbjct: 3016 KHIKDIKVLEKKRAMFECEVSEP--DITVQWMKDDQELQITDR---IKIQKEKYVHRLLI 3070
Query: 100 NKASLADSGEY 110
++D+G+Y
Sbjct: 3071 PSTRMSDAGKY 3081
Score = 28.5 bits (62), Expect = 3.7
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 97 LRINKASLAD-SGEYMCKVISKLGNDSASANITIVE 131
L I+K + D GEY+C+ ++ G + SA +T+V+
Sbjct: 4490 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4525
Score = 28.5 bits (62), Expect = 3.7
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSP--ALPP----------RLKEMKSQESAAGSKLVLRC 57
KG + KE + E+AAG P A PP ++ S E G ++ L
Sbjct: 8337 KGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8396
Query: 58 ETS-SEYSSLRFKWFKNGN-----ELNRKNKP--------------------QNIKIQK- 90
S S Y ++ W K+ N E+ ++ P Q + I
Sbjct: 8397 SISGSPYPTIT--WIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNS 8454
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
K G+S+LR+ + D G YM KV + G A ++++++
Sbjct: 8455 KKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT 8496
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNI---KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSA 123
+ +W KN + + I ++ + K+EL I KA D G Y ++LG+
Sbjct: 9124 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 9183
Query: 124 SANITIVE 131
+ ++ + +
Sbjct: 9184 NVHVEVYD 9191
Score = 28.5 bits (62), Expect = 3.7
Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
++ E ++ LPP++ + AG KL + + KW K +E+ +
Sbjct: 12580 REAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPT-CKWKKGEDEVVTSS 12638
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
++ + K S L I + DSG Y + G D+ + ++++
Sbjct: 12639 ---HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12686
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/69 (21%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF G++L + + ++ ++L I + ++ D+GEY ++ + G S + + I
Sbjct: 23467 WFFAGSKLRESER---VTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23523
Query: 130 VESNEIITG 138
++ TG
Sbjct: 23524 LDKPGPPTG 23532
Score = 28.1 bits (61), Expect = 4.9
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF +G ++ N + + K+ G L I A+ +DSGE+ ++ G S S +T+
Sbjct: 1444 WFHDGQQI--VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW +G+E+ ++ ++ S L I D+GEY V + G+ + + ++T
Sbjct: 11238 KWTTDGSEIKTD---EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11294
Query: 129 IVE 131
+++
Sbjct: 11295 VLD 11297
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W + E K ++I+K ++L I+ D+G+Y+ K+ + G+ SA + +
Sbjct: 17753 WSREEGEFTDK-----VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17807
Query: 130 VES 132
+++
Sbjct: 17808 LDT 17810
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVI 115
CETS + ++ KW+K+G E++ +K + +K S L I+ +D+ +Y C ++
Sbjct: 2150 CETSEPF--VKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTID---TSDAEDYSCVLV 2203
Score = 27.7 bits (60), Expect = 6.4
Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 9/109 (8%)
Query: 24 PESAAGSQS-PALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
PE + Q P PP + ++ ++ G +C S + L+ W+ ++K
Sbjct: 3285 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKVSWYSK----DKKI 3338
Query: 82 KPQNI-KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
KP ++ + +L I +A D G Y + +G S++AN+++
Sbjct: 3339 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K EL++ + I KSEL I A D G Y+ + G+ A+A + +
Sbjct: 8833 WTKEEGELDK----DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8888
Query: 130 VE 131
+
Sbjct: 8889 FD 8890
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 50.4 bits (119), Expect = 9e-07
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 20 SGKKPESAAGSQSPALPPRLK-EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELN 78
SGK SA + P +K +++ E A G CE S ++RF+WFK G E+
Sbjct: 4445 SGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIY 4503
Query: 79 RKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+K I+ S L I + + D GEY CK ++ G+ S +A +T+
Sbjct: 4504 ESDK---CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 11/129 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + + +SQ G ++ CE S E S +WFKN ++ + N+ I +
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISS---NVSISRSRNVY 26817
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIV-----ESNEII--TGMPASTEGAYV 148
L I AS++DSG+Y K + G SA+A++ ++ S E++ T S +G++
Sbjct: 26818 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 26877
Query: 149 SSATSTSTT 157
S + S +
Sbjct: 26878 SQSVQMSAS 26886
Score = 44.7 bits (104), Expect = 5e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
Query: 52 KLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYM 111
++ L+CE S + + KWFK+G E+ K I+ + L+I KA L D GEY+
Sbjct: 5307 EITLKCEVSKD---VPVKWFKDGEEIVPSPK---YSIKADGLRRILKIKKADLKDKGEYV 5360
Query: 112 CKVISKLGNDSASANITI 129
C G D AN+T+
Sbjct: 5361 C----DCGTDKTKANVTV 5374
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
E AG PA P + + Q+ G +V C+ + W K+G L +
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVY-WKKSGVPLTTGYR-Y 1082
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
+ K+ G+ +L I+ D+GEY V +K G SASA++ E++ M + E
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL--MKSQQE 1140
Query: 145 GAYVSSATS 153
Y + T+
Sbjct: 1141 MLYQTQVTA 1149
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 33 PALPPRLKE-MKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKK 91
P PP L +K+ G + L C S Y S W++ ++ + +I +
Sbjct: 893 PVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQIESSI---DFQITFQ 948
Query: 92 PGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
G + L I +A DSG + C +++ G S S + + S E A TE
Sbjct: 949 SGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE 1001
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/135 (23%), Positives = 49/135 (36%), Gaps = 3/135 (2%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK 69
KG+G K +S P P LKE+K A G + E +
Sbjct: 3674 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT-VT 3732
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WFK +L I G +N DSG Y+CK + LG + +A + +
Sbjct: 3733 WFKENKQLC--TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Query: 130 VESNEIITGMPASTE 144
+ + +T P +
Sbjct: 3791 LLEDTDMTDTPCKAK 3805
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
CE S E + + KWFK+G E+ + K I K L INK L D EY C+V +
Sbjct: 6023 CELSRE--NAKVKWFKDGAEIKKGKK---YDIISKGAVRILVINKCLLDDEAEYSCEVRT 6077
Query: 117 KLGNDSASANITIVESNEIITGMPASTE 144
S +T++E + T A+ E
Sbjct: 6078 A----RTSGMLTVLEEEAVFTKNLANIE 6101
Score = 37.4 bits (85), Expect = 0.008
Identities = 16/60 (26%), Positives = 28/60 (46%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W+K+G ++ + + + G +L IN + D EY +K G DS A +T+
Sbjct: 25351 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 37.4 bits (85), Expect = 0.008
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK---WFKNGNELNRKNKPQNIKIQKKP 92
PP++ + E+ SK + + E S LR K W+K+G +L Q
Sbjct: 26345 PPKITQFLKAEA---SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFH--YSAD 26399
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSAS 124
G EL+IN + +D GEY+C++ + G +
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTN 26431
Score = 36.6 bits (83), Expect = 0.014
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 14 KKKERGSG--KKPESAAGS-QSPALPPR-LKEMK----SQESAAGSKLVLRCETSSEYSS 65
+K GSG K P+ A + Q A+P + +KE+K ++ GS + C S S+
Sbjct: 4717 RKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP--ST 4774
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
W K+G+ + K + I K +L I L+D+GEY C + +LGN ++
Sbjct: 4775 AITTWMKDGSNIRESPKHRFIADGKD---RKLHIIDVQLSDAGEYTC--VLRLGNKEKTS 4829
Query: 126 NITIV 130
+V
Sbjct: 4830 TAKLV 4834
Score = 36.2 bits (82), Expect = 0.018
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G + + K K+ + G L I+K +DSG Y C V + G+ S+S +TI
Sbjct: 26513 WTKDGKAITQGGK---YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26569
Score = 35.4 bits (80), Expect = 0.031
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNK 82
K ++ Q G+ VL CE S E + + KWFKNG E+ + K
Sbjct: 5917 KPLEDQTVEEGATAVLECEVSRE--NAKVKWFKNGTEILKSKK 5957
Score = 34.7 bits (78), Expect = 0.052
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G E+ ++ + ++ + L + K+ AD+G Y + +KLG+ +AS N+ +
Sbjct: 8048 WHKDGKEVKASDR---LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Query: 130 VESNEIITGMPASTEGAYVSSATSTS 155
+ G+P + S T +S
Sbjct: 8105 I-------GLPGPCKDIKASDITKSS 8123
Score = 34.7 bits (78), Expect = 0.052
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNI-KIQKKPGKSELRINKASLADS 107
AG +VL + + W K G ++ +P +I +I P S L I A+ D+
Sbjct: 14020 AGDTIVLNAISILGKPLPKSSWSKAGKDI----RPSDITQITSTPTSSMLTIKYATRKDA 14075
Query: 108 GEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTST 156
GEY + G +T+++ + G P E + VS+ +T T
Sbjct: 14076 GEYTITATNPFGTKVEHVKVTVLD----VPGPPGPVEISNVSAEKATLT 14120
Score = 34.3 bits (77), Expect = 0.068
Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
C+ + S + W+ +L K +I + G + L + + D G Y CKV++
Sbjct: 25217 CKIENYDQSTQVTWYFGVRQLENSEK---YEITYEDGVAILYVKDITKLDDGTYRCKVVN 25273
Query: 117 KLGNDSASANITIVESNEI 135
G DS+ A + + E+
Sbjct: 25274 DYGEDSSYAELFVKGVREV 25292
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK+ + +E ++V CE ++E + KWF+N + +K I +K LR
Sbjct: 6274 LKDTRVKEQ---QEVVFNCEVNTE--GAKAKWFRNEEAIFDSSK---YIILQKDLVYTLR 6325
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEI 135
I A L D Y + + G + SA IVE ++
Sbjct: 6326 IRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDL 6362
Score = 32.7 bits (73), Expect = 0.20
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
++ ++ Q V C+ S E +++ KW++NG E+ K K +K L
Sbjct: 6454 VEHLEDQTVTEFDDAVFSCQLSREKANV--KWYRNGREIKEGKK---YKFEKDGSIHRLI 6508
Query: 99 INKASLADSGEYMCKV 114
I L D EY C V
Sbjct: 6509 IKDCRLDDECEYACGV 6524
Score = 32.0 bits (71), Expect = 0.34
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K + Q A + V CE ++ S + +W ++G L N NI+ + K L I
Sbjct: 2578 KPLTDQTVAESQEAVFECEVANPDS--KGEWLRDGKHLPLTN---NIRSESDGHKRRLII 2632
Query: 100 NKASLADSGEYMCKV 114
L D GEY KV
Sbjct: 2633 AATKLDDIGEYTYKV 2647
Score = 31.6 bits (70), Expect = 0.44
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E K + E + Y + +KW KNG E+ +K Q ++ K L
Sbjct: 2929 LKDINAEE-----KDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQ---MRTKKLTHSLN 2980
Query: 99 INKASLADSGEY 110
I D+ +Y
Sbjct: 2981 IRNVHFGDAADY 2992
Score = 30.4 bits (67), Expect = 0.99
Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 3/68 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+W +G L N+ +++ + G L A DSG C+ +K G D SA +
Sbjct: 1691 EWLHDGKPLEAANR---LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Query: 129 IVESNEII 136
+ + ++
Sbjct: 1748 VKDEKSLV 1755
Score = 30.0 bits (66), Expect = 1.3
Identities = 22/100 (22%), Positives = 47/100 (47%), Gaps = 12/100 (12%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E + V E S + ++R KWFKN L + +++ +Q + +
Sbjct: 5563 LKDVTAKEKESA---VFTVELS--HDNIRVKWFKNDQRL---HTTRSVSMQDEGKTHSIT 5614
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG 138
S+ D+ + + + S+ A +T++E + TG
Sbjct: 5615 FKDLSIDDTSQIRVEAMGM----SSEAKLTVLEGDPYFTG 5650
Score = 29.6 bits (65), Expect = 1.7
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+ + + P+ +KI + S+ + KA +D G+Y+ + G+ A A + +
Sbjct: 11863 WTKDKDATDLTRSPR-VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Query: 130 VE 131
++
Sbjct: 11922 LD 11923
Score = 29.6 bits (65), Expect = 1.7
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 35 LPPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP+++ + S S G L + C + E + W G +++ + + + I+
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGRKIHSQEQGR-FHIENTDD 27012
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L I D G Y + ++ G+DSA+ NI I
Sbjct: 27013 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 29.3 bits (64), Expect = 2.2
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +K + + + CE S + +W K+ EL ++ IKIQK+ L I
Sbjct: 3016 KHIKDIKVLEKKRAMFECEVSEP--DITVQWMKDDQELQITDR---IKIQKEKYVHRLLI 3070
Query: 100 NKASLADSGEY 110
++D+G+Y
Sbjct: 3071 PSTRMSDAGKY 3081
Score = 28.5 bits (62), Expect = 3.7
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 97 LRINKASLAD-SGEYMCKVISKLGNDSASANITIVE 131
L I+K + D GEY+C+ ++ G + SA +T+V+
Sbjct: 4423 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4458
Score = 28.5 bits (62), Expect = 3.7
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSP--ALPP----------RLKEMKSQESAAGSKLVLRC 57
KG + KE + E+AAG P A PP ++ S E G ++ L
Sbjct: 8270 KGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8329
Query: 58 ETS-SEYSSLRFKWFKNGN-----ELNRKNKP--------------------QNIKIQK- 90
S S Y ++ W K+ N E+ ++ P Q + I
Sbjct: 8330 SISGSPYPTIT--WIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNS 8387
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
K G+S+LR+ + D G YM KV + G A ++++++
Sbjct: 8388 KKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT 8429
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNI---KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSA 123
+ +W KN + + I ++ + K+EL I KA D G Y ++LG+
Sbjct: 9057 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 9116
Query: 124 SANITIVE 131
+ ++ + +
Sbjct: 9117 NVHVEVYD 9124
Score = 28.5 bits (62), Expect = 3.7
Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
++ E ++ LPP++ + AG KL + + KW K +E+ +
Sbjct: 12513 REAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPT-CKWKKGEDEVVTSS 12571
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
++ + K S L I + DSG Y + G D+ + ++++
Sbjct: 12572 ---HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12619
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/69 (21%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF G++L + + ++ ++L I + ++ D+GEY ++ + G S + + I
Sbjct: 23400 WFFAGSKLRESER---VTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23456
Query: 130 VESNEIITG 138
++ TG
Sbjct: 23457 LDKPGPPTG 23465
Score = 28.1 bits (61), Expect = 4.9
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF +G ++ N + + K+ G L I A+ +DSGE+ ++ G S S +T+
Sbjct: 1444 WFHDGQQI--VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW +G+E+ ++ ++ S L I D+GEY V + G+ + + ++T
Sbjct: 11171 KWTTDGSEIKTD---EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11227
Query: 129 IVE 131
+++
Sbjct: 11228 VLD 11230
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W + E K ++I+K ++L I+ D+G+Y+ K+ + G+ SA + +
Sbjct: 17686 WSREEGEFTDK-----VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17740
Query: 130 VES 132
+++
Sbjct: 17741 LDT 17743
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVI 115
CETS + ++ KW+K+G E++ +K + +K S L I+ +D+ +Y C ++
Sbjct: 2150 CETSEPF--VKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTID---TSDAEDYSCVLV 2203
Score = 27.7 bits (60), Expect = 6.4
Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 9/109 (8%)
Query: 24 PESAAGSQS-PALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
PE + Q P PP + ++ ++ G +C S + L+ W+ ++K
Sbjct: 3285 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKVSWYSK----DKKI 3338
Query: 82 KPQNI-KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
KP ++ + +L I +A D G Y + +G S++AN+++
Sbjct: 3339 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 27.7 bits (60), Expect = 6.4
Identities = 15/61 (24%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+WF N +L K ++ G + + I A +G+Y CK + G + +A +T
Sbjct: 3451 QWFHN-QQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLT 3509
Query: 129 I 129
+
Sbjct: 3510 V 3510
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K EL++ + I KSEL I A D G Y+ + G+ A+A + +
Sbjct: 8766 WTKEEGELDK----DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8821
Query: 130 VE 131
+
Sbjct: 8822 FD 8823
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 50.4 bits (119), Expect = 9e-07
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 20 SGKKPESAAGSQSPALPPRLK-EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELN 78
SGK SA + P +K +++ E A G CE S ++RF+WFK G E+
Sbjct: 4320 SGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIY 4378
Query: 79 RKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+K I+ S L I + + D GEY CK ++ G+ S +A +T+
Sbjct: 4379 ESDK---CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 11/129 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + + +SQ G ++ CE S E S +WFKN ++ + N+ I +
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISS---NVSISRSRNVY 26692
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIV-----ESNEII--TGMPASTEGAYV 148
L I AS++DSG+Y K + G SA+A++ ++ S E++ T S +G++
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 26752
Query: 149 SSATSTSTT 157
S + S +
Sbjct: 26753 SQSVQMSAS 26761
Score = 44.7 bits (104), Expect = 5e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
Query: 52 KLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYM 111
++ L+CE S + + KWFK+G E+ K I+ + L+I KA L D GEY+
Sbjct: 5182 EITLKCEVSKD---VPVKWFKDGEEIVPSPK---YSIKADGLRRILKIKKADLKDKGEYV 5235
Query: 112 CKVISKLGNDSASANITI 129
C G D AN+T+
Sbjct: 5236 C----DCGTDKTKANVTV 5249
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
E AG PA P + + Q+ G +V C+ + W K+G L +
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVY-WKKSGVPLTTGYR-Y 1082
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
+ K+ G+ +L I+ D+GEY V +K G SASA++ E++ M + E
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL--MKSQQE 1140
Query: 145 GAYVSSATS 153
Y + T+
Sbjct: 1141 MLYQTQVTA 1149
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 33 PALPPRLKE-MKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKK 91
P PP L +K+ G + L C S Y S W++ ++ + +I +
Sbjct: 893 PVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQIESSI---DFQITFQ 948
Query: 92 PGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTE 144
G + L I +A DSG + C +++ G S S + + S E A TE
Sbjct: 949 SGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE 1001
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/135 (23%), Positives = 49/135 (36%), Gaps = 3/135 (2%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK 69
KG+G K +S P P LKE+K A G + E +
Sbjct: 3549 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT-VT 3607
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WFK +L I G +N DSG Y+CK + LG + +A + +
Sbjct: 3608 WFKENKQLC--TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Query: 130 VESNEIITGMPASTE 144
+ + +T P +
Sbjct: 3666 LLEDTDMTDTPCKAK 3680
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
CE S E + + KWFK+G E+ + K I K L INK L D EY C+V +
Sbjct: 5898 CELSRE--NAKVKWFKDGAEIKKGKK---YDIISKGAVRILVINKCLLDDEAEYSCEVRT 5952
Query: 117 KLGNDSASANITIVESNEIITGMPASTE 144
S +T++E + T A+ E
Sbjct: 5953 A----RTSGMLTVLEEEAVFTKNLANIE 5976
Score = 37.4 bits (85), Expect = 0.008
Identities = 16/60 (26%), Positives = 28/60 (46%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W+K+G ++ + + + G +L IN + D EY +K G DS A +T+
Sbjct: 25226 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 37.4 bits (85), Expect = 0.008
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK---WFKNGNELNRKNKPQNIKIQKKP 92
PP++ + E+ SK + + E S LR K W+K+G +L Q
Sbjct: 26220 PPKITQFLKAEA---SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFH--YSAD 26274
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSAS 124
G EL+IN + +D GEY+C++ + G +
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTN 26306
Score = 36.6 bits (83), Expect = 0.014
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 14 KKKERGSG--KKPESAAGS-QSPALPPR-LKEMK----SQESAAGSKLVLRCETSSEYSS 65
+K GSG K P+ A + Q A+P + +KE+K ++ GS + C S S+
Sbjct: 4592 RKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP--ST 4649
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
W K+G+ + K + I K +L I L+D+GEY C + +LGN ++
Sbjct: 4650 AITTWMKDGSNIRESPKHRFIADGKD---RKLHIIDVQLSDAGEYTC--VLRLGNKEKTS 4704
Query: 126 NITIV 130
+V
Sbjct: 4705 TAKLV 4709
Score = 36.2 bits (82), Expect = 0.018
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G + + K K+ + G L I+K +DSG Y C V + G+ S+S +TI
Sbjct: 26388 WTKDGKAITQGGK---YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 35.4 bits (80), Expect = 0.031
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNK 82
K ++ Q G+ VL CE S E + + KWFKNG E+ + K
Sbjct: 5792 KPLEDQTVEEGATAVLECEVSRE--NAKVKWFKNGTEILKSKK 5832
Score = 34.7 bits (78), Expect = 0.052
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G E+ ++ + ++ + L + K+ AD+G Y + +KLG+ +AS N+ +
Sbjct: 7923 WHKDGKEVKASDR---LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Query: 130 VESNEIITGMPASTEGAYVSSATSTS 155
+ G+P + S T +S
Sbjct: 7980 I-------GLPGPCKDIKASDITKSS 7998
Score = 34.7 bits (78), Expect = 0.052
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNI-KIQKKPGKSELRINKASLADS 107
AG +VL + + W K G ++ +P +I +I P S L I A+ D+
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDI----RPSDITQITSTPTSSMLTIKYATRKDA 13950
Query: 108 GEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATSTST 156
GEY + G +T+++ + G P E + VS+ +T T
Sbjct: 13951 GEYTITATNPFGTKVEHVKVTVLD----VPGPPGPVEISNVSAEKATLT 13995
Score = 34.3 bits (77), Expect = 0.068
Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
C+ + S + W+ +L K +I + G + L + + D G Y CKV++
Sbjct: 25092 CKIENYDQSTQVTWYFGVRQLENSEK---YEITYEDGVAILYVKDITKLDDGTYRCKVVN 25148
Query: 117 KLGNDSASANITIVESNEI 135
G DS+ A + + E+
Sbjct: 25149 DYGEDSSYAELFVKGVREV 25167
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK+ + +E ++V CE ++E + KWF+N + +K I +K LR
Sbjct: 6149 LKDTRVKEQ---QEVVFNCEVNTE--GAKAKWFRNEEAIFDSSK---YIILQKDLVYTLR 6200
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEI 135
I A L D Y + + G + SA IVE ++
Sbjct: 6201 IRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDL 6237
Score = 32.7 bits (73), Expect = 0.20
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
++ ++ Q V C+ S E +++ KW++NG E+ K K +K L
Sbjct: 6329 VEHLEDQTVTEFDDAVFSCQLSREKANV--KWYRNGREIKEGKK---YKFEKDGSIHRLI 6383
Query: 99 INKASLADSGEYMCKV 114
I L D EY C V
Sbjct: 6384 IKDCRLDDECEYACGV 6399
Score = 32.0 bits (71), Expect = 0.34
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K + Q A + V CE ++ S + +W ++G L N NI+ + K L I
Sbjct: 2578 KPLTDQTVAESQEAVFECEVANPDS--KGEWLRDGKHLPLTN---NIRSESDGHKRRLII 2632
Query: 100 NKASLADSGEYMCKV 114
L D GEY KV
Sbjct: 2633 AATKLDDIGEYTYKV 2647
Score = 31.6 bits (70), Expect = 0.44
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E K + E + Y + +KW KNG E+ +K Q ++ K L
Sbjct: 2929 LKDINAEE-----KDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQ---MRTKKLTHSLN 2980
Query: 99 INKASLADSGEY 110
I D+ +Y
Sbjct: 2981 IRNVHFGDAADY 2992
Score = 30.4 bits (67), Expect = 0.99
Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 3/68 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+W +G L N+ +++ + G L A DSG C+ +K G D SA +
Sbjct: 1691 EWLHDGKPLEAANR---LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Query: 129 IVESNEII 136
+ + ++
Sbjct: 1748 VKDEKSLV 1755
Score = 30.0 bits (66), Expect = 1.3
Identities = 22/100 (22%), Positives = 47/100 (47%), Gaps = 12/100 (12%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E + V E S + ++R KWFKN L + +++ +Q + +
Sbjct: 5438 LKDVTAKEKESA---VFTVELS--HDNIRVKWFKNDQRL---HTTRSVSMQDEGKTHSIT 5489
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG 138
S+ D+ + + + S+ A +T++E + TG
Sbjct: 5490 FKDLSIDDTSQIRVEAMGM----SSEAKLTVLEGDPYFTG 5525
Score = 29.6 bits (65), Expect = 1.7
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+ + + P+ +KI + S+ + KA +D G+Y+ + G+ A A + +
Sbjct: 11738 WTKDKDATDLTRSPR-VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Query: 130 VE 131
++
Sbjct: 11797 LD 11798
Score = 29.6 bits (65), Expect = 1.7
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 35 LPPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP+++ + S S G L + C + E + W G +++ + + + I+
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGRKIHSQEQGR-FHIENTDD 26887
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L I D G Y + ++ G+DSA+ NI I
Sbjct: 26888 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 29.3 bits (64), Expect = 2.2
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +K + + + CE S + +W K+ EL ++ IKIQK+ L I
Sbjct: 3016 KHIKDIKVLEKKRAMFECEVSEP--DITVQWMKDDQELQITDR---IKIQKEKYVHRLLI 3070
Query: 100 NKASLADSGEY 110
++D+G+Y
Sbjct: 3071 PSTRMSDAGKY 3081
Score = 28.5 bits (62), Expect = 3.7
Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 9/116 (7%)
Query: 24 PESAAGSQS-PALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
PE + Q P PP + ++ ++ G +C S + L+ W+ ++K
Sbjct: 3285 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKVSWYSK----DKKI 3338
Query: 82 KPQNI-KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEII 136
KP ++ + +L I +A D G Y + +G S++AN+++ I+
Sbjct: 3339 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESIL 3394
Score = 28.5 bits (62), Expect = 3.7
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 97 LRINKASLAD-SGEYMCKVISKLGNDSASANITIVE 131
L I+K + D GEY+C+ ++ G + SA +T+V+
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4333
Score = 28.5 bits (62), Expect = 3.7
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSP--ALPP----------RLKEMKSQESAAGSKLVLRC 57
KG + KE + E+AAG P A PP ++ S E G ++ L
Sbjct: 8145 KGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8204
Query: 58 ETS-SEYSSLRFKWFKNGN-----ELNRKNKP--------------------QNIKIQK- 90
S S Y ++ W K+ N E+ ++ P Q + I
Sbjct: 8205 SISGSPYPTIT--WIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNS 8262
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
K G+S+LR+ + D G YM KV + G A ++++++
Sbjct: 8263 KKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT 8304
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNI---KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSA 123
+ +W KN + + I ++ + K+EL I KA D G Y ++LG+
Sbjct: 8932 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 8991
Query: 124 SANITIVE 131
+ ++ + +
Sbjct: 8992 NVHVEVYD 8999
Score = 28.5 bits (62), Expect = 3.7
Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
++ E ++ LPP++ + AG KL + + KW K +E+ +
Sbjct: 12388 REAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPT-CKWKKGEDEVVTSS 12446
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
++ + K S L I + DSG Y + G D+ + ++++
Sbjct: 12447 ---HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12494
Score = 28.5 bits (62), Expect = 3.7
Identities = 15/69 (21%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF G++L + + ++ ++L I + ++ D+GEY ++ + G S + + I
Sbjct: 23275 WFFAGSKLRESER---VTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23331
Query: 130 VESNEIITG 138
++ TG
Sbjct: 23332 LDKPGPPTG 23340
Score = 28.1 bits (61), Expect = 4.9
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF +G ++ N + + K+ G L I A+ +DSGE+ ++ G S S +T+
Sbjct: 1444 WFHDGQQI--VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW +G+E+ ++ ++ S L I D+GEY V + G+ + + ++T
Sbjct: 11046 KWTTDGSEIKTD---EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11102
Query: 129 IVE 131
+++
Sbjct: 11103 VLD 11105
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W + E K ++I+K ++L I+ D+G+Y+ K+ + G+ SA + +
Sbjct: 17561 WSREEGEFTDK-----VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17615
Query: 130 VES 132
+++
Sbjct: 17616 LDT 17618
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVI 115
CETS + ++ KW+K+G E++ +K + +K S L I+ +D+ +Y C ++
Sbjct: 2150 CETSEPF--VKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTID---TSDAEDYSCVLV 2203
Score = 27.7 bits (60), Expect = 6.4
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K EL++ + I KSEL I A D G Y+ + G+ A+A + +
Sbjct: 8641 WTKEEGELDK----DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Query: 130 VE 131
+
Sbjct: 8697 FD 8698
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,597,134
Number of Sequences: 37866
Number of extensions: 331072
Number of successful extensions: 3389
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 200
Number of HSP's that attempted gapping in prelim test: 2277
Number of HSP's gapped (non-prelim): 1218
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.