Search of human proteins with 23510451

Search of human proteins with 23510451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]
         (732 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]         1501   0.0  
gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]                      72   2e-12
gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]            56   1e-07
gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]            56   1e-07
gi|16933540 fibroblast activation protein, alpha subunit [Homo s...    53   1e-06
gi|86792863 dipeptidyl-peptidase 6 isoform 3 [Homo sapiens]            52   3e-06
gi|86792778 dipeptidyl-peptidase 6 isoform 2 [Homo sapiens]            52   3e-06
gi|86792774 dipeptidyl-peptidase 6 isoform 1 [Homo sapiens]            52   3e-06
gi|18765694 dipeptidylpeptidase IV [Homo sapiens]                      37   0.065
gi|28629871 hypothetical protein LOC140701 [Homo sapiens]              35   0.25 
gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]       35   0.32 
gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]        35   0.32 
gi|41349456 prolyl endopeptidase [Homo sapiens]                        35   0.32 
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s...    34   0.42 
gi|33563374 carboxylesterase 3 [Homo sapiens]                          34   0.55 
gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a ...    33   0.94 
gi|119372302 pepsinogen 4, group I [Homo sapiens]                      32   1.6  
gi|119372298 pepsinogen 3, group I [Homo sapiens]                      32   1.6  
gi|23943854 pepsinogen 5, group I [Homo sapiens]                       32   2.1  
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    32   2.1  
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...    32   2.7  
gi|239753870 PREDICTED: hypothetical protein [Homo sapiens]            32   2.7  
gi|239748431 PREDICTED: hypothetical protein XP_002346666 [Homo ...    32   2.7  
gi|239742365 PREDICTED: hypothetical protein XP_002342523 [Homo ...    32   2.7  
gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]           31   3.6  
gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]           31   3.6  
gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]                   30   6.1  

>gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]
          Length = 732

 Score = 1501 bits (3885), Expect = 0.0
 Identities = 732/732 (100%), Positives = 732/732 (100%)

Query: 1   MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLERMEN 60
           MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLERMEN
Sbjct: 1   MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLERMEN 60

Query: 61  IRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGPGEEKQF 120
           IRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGPGEEKQF
Sbjct: 61  IRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGPGEEKQF 120

Query: 121 LEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTK 180
           LEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTK
Sbjct: 121 LEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTK 180

Query: 181 ALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLCVLDVESGNISVLEGV 240
           ALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLCVLDVESGNISVLEGV
Sbjct: 181 ALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLCVLDVESGNISVLEGV 240

Query: 241 PENVSPGQAFWAPGDAGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLIGGKCELLSDDSL 300
           PENVSPGQAFWAPGDAGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLIGGKCELLSDDSL
Sbjct: 241 PENVSPGQAFWAPGDAGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLIGGKCELLSDDSL 300

Query: 301 AVSSPRLSPDQCRIVYLQYPSLIPHHQCSQLCLYDWYTKVTSVVVDVVPRQLGENFSGIY 360
           AVSSPRLSPDQCRIVYLQYPSLIPHHQCSQLCLYDWYTKVTSVVVDVVPRQLGENFSGIY
Sbjct: 301 AVSSPRLSPDQCRIVYLQYPSLIPHHQCSQLCLYDWYTKVTSVVVDVVPRQLGENFSGIY 360

Query: 361 CSLLPLGCWSADSQRVVFDSAQRSRQDLFAVDTQVGTVTSLTAGGSGGSWKLLTIDQDLM 420
           CSLLPLGCWSADSQRVVFDSAQRSRQDLFAVDTQVGTVTSLTAGGSGGSWKLLTIDQDLM
Sbjct: 361 CSLLPLGCWSADSQRVVFDSAQRSRQDLFAVDTQVGTVTSLTAGGSGGSWKLLTIDQDLM 420

Query: 421 VAQFSTPSLPPTLKVGFLPSAGKEQSVLWVSLEEAEPIPDIHWGIRVLQPPPEQENVQYA 480
           VAQFSTPSLPPTLKVGFLPSAGKEQSVLWVSLEEAEPIPDIHWGIRVLQPPPEQENVQYA
Sbjct: 421 VAQFSTPSLPPTLKVGFLPSAGKEQSVLWVSLEEAEPIPDIHWGIRVLQPPPEQENVQYA 480

Query: 481 GLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
           GLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS
Sbjct: 481 GLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540

Query: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQY 600
           TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQY
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQY 600

Query: 601 PETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYI 660
           PETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYI
Sbjct: 601 PETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYI 660

Query: 661 PQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALSEVEVESDSFM 720
           PQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALSEVEVESDSFM
Sbjct: 661 PQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALSEVEVESDSFM 720

Query: 721 NAVLWLRTHLGS 732
           NAVLWLRTHLGS
Sbjct: 721 NAVLWLRTHLGS 732


>gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]
          Length = 892

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 86/335 (25%), Positives = 147/335 (43%), Gaps = 49/335 (14%)

Query: 396 GTVTSLTAGGSGGSWKLLTIDQDLMVAQFSTPSLPPTLKVGFLPSAGKE----QSVLWVS 451
           G +  LT  G   S  + + + D+ V+ +S+ S PP + V  L     +    Q   W S
Sbjct: 565 GEIVRLTTPGFSHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWAS 623

Query: 452 LEEAEPIPDIHWGIRVLQPPPE------QENVQYAGLDFEAILLQPGSPPDKTQVPMVVM 505
           + EA   P  +        PPE      + +V+  G+ ++   LQPG      + P V+ 
Sbjct: 624 MMEAASCPPDY-------VPPEIFHFHTRSDVRLYGMIYKPHALQPGK-----KHPTVLF 671

Query: 506 PHGGP-----HSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDV 560
            +GGP     ++SF     L    L  +G+AV++++ RGS   G     +L   +G  ++
Sbjct: 672 VYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEI 731

Query: 561 KDVQFAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQYPETYRACVARNPV-INIAS 618
           +D    ++ V ++  F D S VA+ G S+GGF+S   +   P+ ++  +A  PV + +A 
Sbjct: 732 EDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAY 791

Query: 619 MLGST----DIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYIPQVKTPLLLMLGQE 674
             G T    D+P+    + G+   S     +++  E L   P R        LL++ G  
Sbjct: 792 DTGYTERYMDVPE--NNQHGYEAGS-----VALHVEKLPNEPNR--------LLILHGFL 836

Query: 675 DRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHAL 709
           D  V F         L     P +L +YP   H++
Sbjct: 837 DENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSI 871


>gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]
          Length = 898

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 76/351 (21%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 396 GTVTSLTAGGSGGSWKLLTIDQDLMVAQFSTPSLPPTLKVGFLPSAGKEQSV----LWVS 451
           G VT LT  G   S   ++   D  ++++S    P  + +  L S   + +      W +
Sbjct: 561 GEVTRLTDRGYSHSC-CISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWAT 619

Query: 452 -LEEAEPIPDIHWGIRVLQPPPEQENVQYA-GLDFEAILLQPGSPPDKTQVPMVVMPHGG 509
            L+ A P+PD          PPE  + +   G     +L +P       + P V+  +GG
Sbjct: 620 ILDSAGPLPDY--------TPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGG 671

Query: 510 P-----HSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQ 564
           P     ++ F          L  +G+ V++++ RGS   G     +    +G  ++ D  
Sbjct: 672 PQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQV 731

Query: 565 FAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGST 623
             ++ +     F D   V + G S+GG++S   + Q  + +R  +A  PV          
Sbjct: 732 EGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTL-------- 783

Query: 624 DIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIR--YIPQVKTPLLLMLGQEDRRVPFK 681
               W   + G+       PD +     L    ++    P     LLL+ G  D  V F 
Sbjct: 784 ----WIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFA 839

Query: 682 QGMEYYRALKTRNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLRTHLGS 732
                   L     P  L +YP+  H++   E      ++ + +L+ +LGS
Sbjct: 840 HTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGS 890


>gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]
          Length = 882

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 76/351 (21%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 396 GTVTSLTAGGSGGSWKLLTIDQDLMVAQFSTPSLPPTLKVGFLPSAGKEQSV----LWVS 451
           G VT LT  G   S   ++   D  ++++S    P  + +  L S   + +      W +
Sbjct: 545 GEVTRLTDRGYSHSC-CISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWAT 603

Query: 452 -LEEAEPIPDIHWGIRVLQPPPEQENVQYA-GLDFEAILLQPGSPPDKTQVPMVVMPHGG 509
            L+ A P+PD          PPE  + +   G     +L +P       + P V+  +GG
Sbjct: 604 ILDSAGPLPDY--------TPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGG 655

Query: 510 P-----HSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQ 564
           P     ++ F          L  +G+ V++++ RGS   G     +    +G  ++ D  
Sbjct: 656 PQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQV 715

Query: 565 FAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGST 623
             ++ +     F D   V + G S+GG++S   + Q  + +R  +A  PV          
Sbjct: 716 EGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTL-------- 767

Query: 624 DIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIR--YIPQVKTPLLLMLGQEDRRVPFK 681
               W   + G+       PD +     L    ++    P     LLL+ G  D  V F 
Sbjct: 768 ----WIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFA 823

Query: 682 QGMEYYRALKTRNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLRTHLGS 732
                   L     P  L +YP+  H++   E      ++ + +L+ +LGS
Sbjct: 824 HTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGS 874


>gi|16933540 fibroblast activation protein, alpha subunit [Homo
           sapiens]
          Length = 760

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 63/281 (22%), Positives = 110/281 (39%), Gaps = 42/281 (14%)

Query: 457 PIPDIHWG-----IRVLQPPPEQENV---------QYAGLDFEAI-----LLQPGSPPDK 497
           PI  +H G     I++L+   E EN          +   L+ + I     ++ P      
Sbjct: 472 PISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRS 531

Query: 498 TQVPMVVMPHGGP-----HSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLP 552
            + P+++  +GGP      S F   W+ + A   K G  + LV+ RG+   G   + ++ 
Sbjct: 532 KKYPLLIQVYGGPCSQSVRSVFAVNWISYLAS--KEGMVIALVDGRGTAFQGDKLLYAVY 589

Query: 553 GNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQYPETYRACVARNP 612
             +G  +V+D   AV + ++    D   +A+ G S+GG++S   +      ++  +A  P
Sbjct: 590 RKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAP 649

Query: 613 VIN---IASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYIPQVKTPLLL 669
           V +    AS+     +        G P   D L        M      R +       LL
Sbjct: 650 VSSWEYYASVYTERFM--------GLPTKDDNLEHYKNSTVMARAEYFRNV-----DYLL 696

Query: 670 MLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
           + G  D  V F+   +  +AL    V  + + Y    H LS
Sbjct: 697 IHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLS 737


>gi|86792863 dipeptidyl-peptidase 6 isoform 3 [Homo sapiens]
          Length = 801

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 53/259 (20%), Positives = 104/259 (40%), Gaps = 15/259 (5%)

Query: 470 PPPEQENVQYAGLDFEAILLQPGSPPDKTQVPMVVMPHGGPHS-----SFVTAWMLFPAM 524
           P  E  +++    +    +L+P +  D T  P++++  G P S      F  +W     M
Sbjct: 528 PKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWE--TVM 585

Query: 525 LCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALM 584
           +   G  V+  + RGS   G   +  +   +G  + KD   AV  +L+E++ D + VA+ 
Sbjct: 586 VSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVF 645

Query: 585 GGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPD 644
           G  +GG++S +++    E       +       S L  + I D+ +  + F      L  
Sbjct: 646 GKDYGGYLSTYILPAKGEN------QGQTFTCGSAL--SPITDFKLYASAFSERYLGLHG 697

Query: 645 LSVWAEMLDKSPIRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPK 704
           L   A  + K   R     +   L++    D ++ F+   E    L        L +YP 
Sbjct: 698 LDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPD 757

Query: 705 STHALSEVEVESDSFMNAV 723
            +H  +   ++   + + +
Sbjct: 758 ESHYFTSSSLKQHLYRSII 776


>gi|86792778 dipeptidyl-peptidase 6 isoform 2 [Homo sapiens]
          Length = 803

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 53/259 (20%), Positives = 104/259 (40%), Gaps = 15/259 (5%)

Query: 470 PPPEQENVQYAGLDFEAILLQPGSPPDKTQVPMVVMPHGGPHS-----SFVTAWMLFPAM 524
           P  E  +++    +    +L+P +  D T  P++++  G P S      F  +W     M
Sbjct: 530 PKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWE--TVM 587

Query: 525 LCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALM 584
           +   G  V+  + RGS   G   +  +   +G  + KD   AV  +L+E++ D + VA+ 
Sbjct: 588 VSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVF 647

Query: 585 GGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPD 644
           G  +GG++S +++    E       +       S L  + I D+ +  + F      L  
Sbjct: 648 GKDYGGYLSTYILPAKGEN------QGQTFTCGSAL--SPITDFKLYASAFSERYLGLHG 699

Query: 645 LSVWAEMLDKSPIRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPK 704
           L   A  + K   R     +   L++    D ++ F+   E    L        L +YP 
Sbjct: 700 LDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPD 759

Query: 705 STHALSEVEVESDSFMNAV 723
            +H  +   ++   + + +
Sbjct: 760 ESHYFTSSSLKQHLYRSII 778


>gi|86792774 dipeptidyl-peptidase 6 isoform 1 [Homo sapiens]
          Length = 865

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 53/259 (20%), Positives = 104/259 (40%), Gaps = 15/259 (5%)

Query: 470 PPPEQENVQYAGLDFEAILLQPGSPPDKTQVPMVVMPHGGPHS-----SFVTAWMLFPAM 524
           P  E  +++    +    +L+P +  D T  P++++  G P S      F  +W     M
Sbjct: 592 PKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWE--TVM 649

Query: 525 LCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALM 584
           +   G  V+  + RGS   G   +  +   +G  + KD   AV  +L+E++ D + VA+ 
Sbjct: 650 VSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVF 709

Query: 585 GGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPD 644
           G  +GG++S +++    E       +       S L  + I D+ +  + F      L  
Sbjct: 710 GKDYGGYLSTYILPAKGEN------QGQTFTCGSAL--SPITDFKLYASAFSERYLGLHG 761

Query: 645 LSVWAEMLDKSPIRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPK 704
           L   A  + K   R     +   L++    D ++ F+   E    L        L +YP 
Sbjct: 762 LDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPD 821

Query: 705 STHALSEVEVESDSFMNAV 723
            +H  +   ++   + + +
Sbjct: 822 ESHYFTSSSLKQHLYRSII 840


>gi|18765694 dipeptidylpeptidase IV [Homo sapiens]
          Length = 766

 Score = 37.0 bits (84), Expect = 0.065
 Identities = 60/266 (22%), Positives = 109/266 (40%), Gaps = 31/266 (11%)

Query: 464 GIRVLQPPPEQE----NVQYAGLDFEAILLQPGS-------PP--DKTQ-VPMVVMPHGG 509
           G+RVL+     +    NVQ      + I+L           PP  DK++  P+++  + G
Sbjct: 490 GLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAG 549

Query: 510 PHSSFV-TAWMLFPAMLCKMGFAVLLVNYRG-STGFGQDSIL-SLPGNVGHQDVKDVQFA 566
           P S    T + L  A        +++ ++ G  +G+  D I+ ++   +G  +V+D   A
Sbjct: 550 PCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEA 609

Query: 567 VEQVLQEEHFDASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGSTDIP 626
             Q  +    D   +A+ G S+GG+++  ++G     ++  +A  PV          +  
Sbjct: 610 ARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV-------SRWEYY 662

Query: 627 DWCVVE--AGFPFSSDCLPDLSVWAEMLDKSPIRYIPQVKTPLLLMLGQEDRRVPFKQGM 684
           D    E   G P   D   +L  +      S      QV+   LL+ G  D  V F+Q  
Sbjct: 663 DSVYTERYMGLPTPED---NLDHYRNSTVMSRAENFKQVE--YLLIHGTADDNVHFQQSA 717

Query: 685 EYYRALKTRNVPVRLLLYPKSTHALS 710
           +  +AL    V  + + Y    H ++
Sbjct: 718 QISKALVDVGVDFQAMWYTDEDHGIA 743


>gi|28629871 hypothetical protein LOC140701 [Homo sapiens]
          Length = 469

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 529 GFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSH 588
           G++VL  N+    GFG  + +  P      D   +   VE  L   HF  +H+ + G S 
Sbjct: 196 GYSVLGWNH---PGFGSSTGVPFP----QHDANAMDVVVEYALHRLHFPPAHLVVYGWSV 248

Query: 589 GGFISCHLIGQYPE 602
           GGF +      YPE
Sbjct: 249 GGFTATWATMTYPE 262


>gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]
          Length = 789

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 34/175 (19%), Positives = 73/175 (41%), Gaps = 14/175 (8%)

Query: 538 RGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLI 597
           RGS   G   +  +   +G  +VKD   AV+ +L+  + D+  +++ G  +GG+I+  ++
Sbjct: 595 RGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMIL 654

Query: 598 GQYPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPI 657
               + ++      P+ ++     +     +     G P   +     +        S +
Sbjct: 655 KSDEKLFKCGSVVAPITDLKLYASA-----FSERYLGMPSKEESTYQAA--------SVL 701

Query: 658 RYIPQVKTP-LLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALSE 711
             +  +K   +L++ G  D +V F+   E  + L    V   + +YP   H +SE
Sbjct: 702 HNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSE 756


>gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]
          Length = 796

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 34/175 (19%), Positives = 73/175 (41%), Gaps = 14/175 (8%)

Query: 538 RGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLI 597
           RGS   G   +  +   +G  +VKD   AV+ +L+  + D+  +++ G  +GG+I+  ++
Sbjct: 602 RGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMIL 661

Query: 598 GQYPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPI 657
               + ++      P+ ++     +     +     G P   +     +        S +
Sbjct: 662 KSDEKLFKCGSVVAPITDLKLYASA-----FSERYLGMPSKEESTYQAA--------SVL 708

Query: 658 RYIPQVKTP-LLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALSE 711
             +  +K   +L++ G  D +V F+   E  + L    V   + +YP   H +SE
Sbjct: 709 HNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSE 763


>gi|41349456 prolyl endopeptidase [Homo sapiens]
          Length = 710

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 37/165 (22%), Positives = 67/165 (40%), Gaps = 26/165 (15%)

Query: 528 MGFAVLLVNYRGSTGFGQD----SILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVAL 583
           MG  + + N RG   +G+      IL+   N       D Q A E +++E +     + +
Sbjct: 495 MGGILAVANIRGGGEYGETWHKGGILANKQNC----FDDFQCAAEYLIKEGYTSPKRLTI 550

Query: 584 MGGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSD--C 641
            GGS+GG +      Q P+ +   +A+         +G  D+  +     G  +++D  C
Sbjct: 551 NGGSNGGLLVAACANQRPDLFGCVIAQ---------VGVMDMLKFHKYTIGHAWTTDYGC 601

Query: 642 LPDLSVWAEMLDKSPIRYIP-------QVKTPLLLMLGQEDRRVP 679
                 +  ++  SP+  +        Q  + LLL    +DR VP
Sbjct: 602 SDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVP 646


>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
            sapiens]
          Length = 2506

 Score = 34.3 bits (77), Expect = 0.42
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 9/87 (10%)

Query: 42   QYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPA----GNSVETRGELLSRES 97
            Q R  H     RD     +    R+++    G S V   PA    G S   RG     ++
Sbjct: 2230 QERPDHGRARARDQRWSRSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQT 2289

Query: 98   PSG-----TMKAVLRKAGGTGPGEEKQ 119
            PS      +   V+RKAGG+GP +++Q
Sbjct: 2290 PSTPRPHVSYSPVIRKAGGSGPPQQQQ 2316


>gi|33563374 carboxylesterase 3 [Homo sapiens]
          Length = 571

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 1/108 (0%)

Query: 491 PGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYR-GSTGFGQDSIL 549
           P   P  +  P++V  HGG   +         A+       V+ V YR G  GF      
Sbjct: 132 PAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDE 191

Query: 550 SLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLI 597
             PGN G  DV      V++ +     D + V + GGS GG I   L+
Sbjct: 192 HAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLV 239


>gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a
           [Homo sapiens]
          Length = 1701

 Score = 33.1 bits (74), Expect = 0.94
 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%)

Query: 201 IKGDQFVFYEDWGENMVSKSIPVLCVLDVESGNISVLEGVPENVSPGQAFWAPGDAGVVF 260
           +KG   +FYE +G+N + +S    C L  E    S+++ VPE+      F      G V+
Sbjct: 542 LKGCTLLFYETYGKNSMDQSSAPRCALFAED---SIVQSVPEHPKKENVFCLSNSFGDVY 598

Query: 261 V 261
           +
Sbjct: 599 L 599


>gi|119372302 pepsinogen 4, group I [Homo sapiens]
          Length = 388

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 189 DEIARLKKPDQAIKGDQFVFYEDWGENMVSKSI-PVLCVLDVESGNISVLEGVPENVSPG 247
           D I  L  P  +  G   VF   W + +VS+ +  V    D +SG++ +  G+  +   G
Sbjct: 180 DGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTG 239

Query: 248 QAFWAPGDAGVVFVGWW 264
              W P    V   G+W
Sbjct: 240 SLNWVP----VTVEGYW 252


>gi|119372298 pepsinogen 3, group I [Homo sapiens]
          Length = 388

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 189 DEIARLKKPDQAIKGDQFVFYEDWGENMVSKSI-PVLCVLDVESGNISVLEGVPENVSPG 247
           D I  L  P  +  G   VF   W + +VS+ +  V    D +SG++ +  G+  +   G
Sbjct: 180 DGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTG 239

Query: 248 QAFWAPGDAGVVFVGWW 264
              W P    V   G+W
Sbjct: 240 SLNWVP----VTVEGYW 252


>gi|23943854 pepsinogen 5, group I [Homo sapiens]
          Length = 388

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 189 DEIARLKKPDQAIKGDQFVFYEDWGENMVSKSI-PVLCVLDVESGNISVLEGVPENVSPG 247
           D I  L  P  +  G   VF   W + +VS+ +  V    D +SG++ +  G+  +   G
Sbjct: 180 DGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDKSGSVVIFGGIDSSYYTG 239

Query: 248 QAFWAPGDAGVVFVGWW 264
              W P    V   G+W
Sbjct: 240 SLNWVP----VTVEGYW 252


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 55/213 (25%), Positives = 75/213 (35%), Gaps = 61/213 (28%)

Query: 137 ALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKA-ESFFQTKALDVSASDDEIARLK 195
           AL   G VY   C  CL    SE   L      RPK  E    T+ +DVS  D     L 
Sbjct: 628 ALTSTGQVYAWGCGACLGCGSSEATAL------RPKLIEELAATRIVDVSIGDSHCLALS 681

Query: 196 KPDQAIKGDQFVFYEDWGENMVSKSIPVLCVLDVESG------NISVLEGVP-ENVSPGQ 248
             ++            WG N + +     C     +G       +S L+G+  + +S G 
Sbjct: 682 HDNEVYA---------WGNNSMGQ-----CGQGNSTGPITKPKKVSGLDGIAIQQISAGT 727

Query: 249 AF---WA--PGDAGVVFVGWWHEPFRLGIRFCT--NRRSALY-YVDLIGGKCELLSDDSL 300
           +    W   P D  VV    WH P+ + +   T  + RS L  Y D I  +         
Sbjct: 728 SHSLAWTALPRDRQVVA---WHRPYCVDLEESTFSHLRSFLERYCDKINSE--------- 775

Query: 301 AVSSPRLSPDQCRIVYLQYPSLIPHHQCSQLCL 333
                        I  L +PS   HH   +LCL
Sbjct: 776 -------------IPPLPFPSSREHHSFLKLCL 795


>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 12/76 (15%)

Query: 365 PLGCWSADSQRVVFDSAQ----RSRQDLFAVDTQVGTVTSLTAGGSGGSWKLLTIDQDLM 420
           P   WSA   R    S        R+D + V TQ     +L  GG  GSW+ L  +    
Sbjct: 273 PWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWN---- 328

Query: 421 VAQFSTPSLPPTLKVG 436
               S P LP  L VG
Sbjct: 329 ----SMPRLPTDLDVG 340


>gi|239753870 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 140

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 19  GLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLER 57
           G+++ P  S  C  PEV  +  G+   V T  T R LER
Sbjct: 64  GVAKPPTASVPCFRPEVGARVTGRAEVVATSLTSRPLER 102


>gi|239748431 PREDICTED: hypothetical protein XP_002346666 [Homo
           sapiens]
          Length = 140

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 19  GLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLER 57
           G+++ P  S  C  PEV  +  G+   V T  T R LER
Sbjct: 64  GVAKPPTASVPCFRPEVGARVTGRAEVVATSLTSRPLER 102


>gi|239742365 PREDICTED: hypothetical protein XP_002342523 [Homo
           sapiens]
          Length = 140

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 19  GLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLER 57
           G+++ P  S  C  PEV  +  G+   V T  T R LER
Sbjct: 64  GVAKPPTASVPCFRPEVGARVTGRAEVVATSLTSRPLER 102


>gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]
          Length = 458

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 32/189 (16%)

Query: 73  GDSVVFAGP----AGNSVET--RGELLSRESPSGTMKAVLRKAGGTGPGEEKQFLEVWEK 126
           GDSV  +G     +G +V T  +G LL R S SG  + + +K G  G G       VW  
Sbjct: 63  GDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKG-------VWGT 115

Query: 127 NRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKK-----RPKAESFFQ--- 178
             ++  +++  ++   P Y+DD   C+     ET +L + E+       P  + +F+   
Sbjct: 116 PGQV--YDVEEVDVKDPNYDDDQENCV----YETVVLPLDERAFEKTLTPIIQEYFEHGD 169

Query: 179 TKALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLC-----VLDVESGN 233
           T  +     D  +  +K     +     +  +     M SK +  LC       DVE   
Sbjct: 170 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF 229

Query: 234 ISVLEGVPE 242
             +L+ +PE
Sbjct: 230 DKLLKDLPE 238


>gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]
          Length = 469

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 32/189 (16%)

Query: 73  GDSVVFAGP----AGNSVET--RGELLSRESPSGTMKAVLRKAGGTGPGEEKQFLEVWEK 126
           GDSV  +G     +G +V T  +G LL R S SG  + + +K G  G G       VW  
Sbjct: 74  GDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKG-------VWGT 126

Query: 127 NRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKK-----RPKAESFFQ--- 178
             ++  +++  ++   P Y+DD   C+     ET +L + E+       P  + +F+   
Sbjct: 127 PGQV--YDVEEVDVKDPNYDDDQENCV----YETVVLPLDERAFEKTLTPIIQEYFEHGD 180

Query: 179 TKALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLC-----VLDVESGN 233
           T  +     D  +  +K     +     +  +     M SK +  LC       DVE   
Sbjct: 181 TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF 240

Query: 234 ISVLEGVPE 242
             +L+ +PE
Sbjct: 241 DKLLKDLPE 249


>gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]
          Length = 417

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 113 GPGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPK 172
           G G++    ++  +  K+++F  S L K G VY +D FG    +HS      V      K
Sbjct: 130 GKGQDPSGKKIKAEPDKIEAFRAS-LSKLGDVYVNDAFGTAHRAHSS----MVGVNLPHK 184

Query: 173 AESFFQTKALDVSA 186
           A  F   K LD  A
Sbjct: 185 ASGFLMKKELDYFA 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,247,703
Number of Sequences: 37866
Number of extensions: 1516964
Number of successful extensions: 3135
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3119
Number of HSP's gapped (non-prelim): 30
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.