BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] (1914 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 3862 0.0 gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 3736 0.0 gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 3539 0.0 gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 3413 0.0 gi|110349719 titin isoform N2-A [Homo sapiens] 366 e-100 gi|110349717 titin isoform novex-2 [Homo sapiens] 366 e-100 gi|110349713 titin isoform novex-1 [Homo sapiens] 366 e-100 gi|110349715 titin isoform N2-B [Homo sapiens] 366 e-100 gi|146219832 myosin light chain kinase 3 [Homo sapiens] 317 9e-86 gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens] 313 1e-84 gi|14993776 skeletal myosin light chain kinase [Homo sapiens] 312 2e-84 gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens] 306 1e-82 gi|167466233 myosin light chain kinase family, member 4 [Homo sa... 297 8e-80 gi|89363047 death-associated protein kinase 1 [Homo sapiens] 277 6e-74 gi|14670383 death-associated kinase 2 [Homo sapiens] 268 4e-71 gi|4557511 death-associated protein kinase 3 [Homo sapiens] 259 2e-68 gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 246 1e-64 gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 246 1e-64 gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 224 8e-58 gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 223 1e-57 gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 223 1e-57 gi|109255245 serine/threonine kinase 17a [Homo sapiens] 207 1e-52 gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 202 3e-51 gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 202 3e-51 gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 202 3e-51 gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 201 7e-51 gi|157785645 SPEG complex locus [Homo sapiens] 200 1e-50 gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 198 5e-50 gi|4758194 serine/threonine kinase 17B [Homo sapiens] 197 6e-50 gi|27901803 protein serine kinase H1 [Homo sapiens] 191 6e-48 >gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] Length = 1914 Score = 3862 bits (10015), Expect = 0.0 Identities = 1914/1914 (100%), Positives = 1914/1914 (100%) Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG Sbjct: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ Sbjct: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840 Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL Sbjct: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK Sbjct: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960 Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS Sbjct: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020 Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080 Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140 Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260 Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500 Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560 Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620 Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680 Query: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM Sbjct: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740 Query: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV Sbjct: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800 Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD Sbjct: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 Query: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Sbjct: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 >gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] Length = 1863 Score = 3736 bits (9687), Expect = 0.0 Identities = 1863/1914 (97%), Positives = 1863/1914 (97%), Gaps = 51/1914 (2%) Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG Sbjct: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ Sbjct: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840 Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL Sbjct: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK Sbjct: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960 Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS Sbjct: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020 Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080 Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140 Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260 Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500 Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560 Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620 Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1654 Query: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740 NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM Sbjct: 1655 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1689 Query: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV Sbjct: 1690 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749 Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD Sbjct: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809 Query: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Sbjct: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863 >gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] Length = 1845 Score = 3539 bits (9177), Expect = 0.0 Identities = 1790/1914 (93%), Positives = 1800/1914 (94%), Gaps = 69/1914 (3%) Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358 Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420 PGLG V+S + R R + FP + Sbjct: 359 --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 SQ+V ++ R + G F E P S EV E+ + C Sbjct: 390 GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT Sbjct: 436 ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471 Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV Sbjct: 472 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG Sbjct: 532 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ Sbjct: 592 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771 Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL Sbjct: 772 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831 Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK Sbjct: 832 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891 Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS Sbjct: 892 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951 Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG Sbjct: 952 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011 Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT Sbjct: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071 Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131 Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK Sbjct: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191 Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ Sbjct: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE Sbjct: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311 Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD Sbjct: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431 Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER Sbjct: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491 Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV Sbjct: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551 Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF Sbjct: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1611 Query: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM Sbjct: 1612 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1671 Query: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV Sbjct: 1672 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1731 Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD Sbjct: 1732 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1791 Query: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Sbjct: 1792 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1845 >gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] Length = 1794 Score = 3413 bits (8849), Expect = 0.0 Identities = 1739/1914 (90%), Positives = 1749/1914 (91%), Gaps = 120/1914 (6%) Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180 Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358 Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420 PGLG V+S + R R + FP + Sbjct: 359 --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 SQ+V ++ R + G F E P S EV E+ + C Sbjct: 390 GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT Sbjct: 436 ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471 Query: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV Sbjct: 472 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG Sbjct: 532 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ Sbjct: 592 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771 Query: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL Sbjct: 772 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831 Query: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK Sbjct: 832 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891 Query: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS Sbjct: 892 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951 Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG Sbjct: 952 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011 Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT Sbjct: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071 Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131 Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK Sbjct: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191 Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ Sbjct: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE Sbjct: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311 Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD Sbjct: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431 Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER Sbjct: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491 Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV Sbjct: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551 Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL Sbjct: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1585 Query: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740 NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM Sbjct: 1586 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1620 Query: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV Sbjct: 1621 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680 Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD Sbjct: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740 Query: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Sbjct: 1741 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 366 bits (939), Expect = e-100 Identities = 238/812 (29%), Positives = 389/812 (47%), Gaps = 79/812 (9%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154 AP FK++L++++V L C+V+ P + W GK + K+ I +G Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + I +D +Y+ A N G + + V+ Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 31020 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 P K +P + +R GE V + +G TW K Sbjct: 31021 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 31064 Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 + I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP Sbjct: 31065 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 31124 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393 P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V + Sbjct: 31125 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 31183 Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453 L Y+FRV A N +G S+PS+ SE T E + E D+ EV + Sbjct: 31184 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 31240 Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513 ++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+ Sbjct: 31241 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 31299 Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573 N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E + Sbjct: 31300 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 31359 Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633 +++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV Sbjct: 31360 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 31419 Query: 1634 NYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAK 1693 ++ + ATDMWS+G + Y+L+SG++PF+ + + + + N+ +A + FD+EAF EIS +A Sbjct: 31420 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 31479 Query: 1694 DFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1753 DF+ LL K+ K+R+ ++ LQHPWL + + + K + + ++Y +K N V Sbjct: 31480 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 31538 Query: 1754 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1813 + R+S I +S G + + +E VS + AV EE HVK Sbjct: 31539 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 31586 Query: 1814 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 + CKIE Y +V W+ + + S ++I Y EDG L + D+ Sbjct: 31587 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 31631 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 DD Y CK VN GE + AEL V+ + E Sbjct: 31632 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 31663 Score = 217 bits (553), Expect = 8e-56 Identities = 286/1264 (22%), Positives = 491/1264 (38%), Gaps = 198/1264 (15%) Query: 31 EAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89 +APA F+ + I++G EG G P VTW +NG +T R C I T Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQR----CNITTTE 7920 Query: 90 SLVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146 I + ED G+Y C N SG + ++ + Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE--------------------- 7959 Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206 PP F +L V V G C++ G P+ V+W KG+ L+P+ Sbjct: 7960 -------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTT 8006 Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266 + +N + L + V+ +D G Y C N G+ S S L++Q SF R+ + Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE-QKLPPSFSRQLR- 8064 Query: 267 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326 DV++ V + + + E + S W + +P K Sbjct: 8065 ---DVQETVGLPVVFDCAISGSEPISVS-------------WYKDGKP----------LK 8098 Query: 327 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386 DSP QT L T++ + R S +G+ P Sbjct: 8099 DSPNV--QTSFLDNTATLNIFKTDR-------------SLAGQYSCTATNP--------- 8134 Query: 387 PGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVA 446 +GS + ++ R I EG+ P F+ + + ++ F C V+G +V+ Sbjct: 8135 --IGS----ASSSARLILTEGKNP---PFFDIRLAPVDAVVGESADFECHVTGTQPIKVS 8185 Query: 447 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-E 505 W + +R G ++ S +L +LK DSG Y+C A N G+ SC+ L + E Sbjct: 8186 WAKDSREIR-SGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 8244 Query: 506 RLAVMEVAPSFSSVLKDCAV-IEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTC 561 RL + PSF+ L + EG F L+ V G+ + W N QP T Sbjct: 8245 RL----IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF 8300 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621 + L ++ A D G YTC N G C++ + + E P KP Sbjct: 8301 KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE--------------PKKP- 8345 Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 P+F Q L+ + V +G V ++ V G+ P + WL G EI+ S+ F L Sbjct: 8346 -PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLE 8404 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-----------DGTQPWFISKPRSV 730 +++V D+G Y C+A N AG T++ +T+++ DG + +F+S+P+S+ Sbjct: 8405 LRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDG-RLFFVSEPQSI 8463 Query: 731 TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790 + + GDP P V W + G + Q D L ++ +G Sbjct: 8464 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSG 8523 Query: 791 QYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPASCEDLCGGGVGADGGGSDRYGS 848 Y + N GE V+L + + G R + G G + D Sbjct: 8524 LYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEE-EEIDIMEL 8582 Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTK 908 L+ P + + D RG+L+ +Q EE + E+E+++ R +K + Sbjct: 8583 LKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIE-RSERDEKEFEE 8641 Query: 909 TLSEDDLKEIPAEQMDFRANLQRQVKPK---TVSEEERKVHSPQQVDFRSVLAKKGTSKT 965 +S + E + +++ Q K V E + K++ P+ + KGT K Sbjct: 8642 LVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPE----IKLSWYKGTEKL 8697 Query: 966 PVPEKVPPPKPATPDFRSVLGGKKKLPAEN----GSSSAETLNAKAVESSKPLSNAQPSG 1021 +P+ S+ G + L +N + + + S+K L+ +P+ Sbjct: 8698 ---------EPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAK-LTVIEPAW 8747 Query: 1022 P--LKPVGNAKPAETLK-----PMGNAKP-----AETLKPMGNAKP--DENLKSASKEEL 1067 L+ V K +T + N K LKP G K + + + ++ Sbjct: 8748 ERHLQDV-TLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 8806 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 + + + CK T E R E++ F +++Q++ V+E + +C+VS D A Sbjct: 8807 RAEDQGQYTCKYEDL-ETSAELRIEAEPI--QFTKRIQNIVVSEHQSATFECEVSFD-DA 8862 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAK-NDAGQAECSCQVT 1186 + W L ++ +G ++I P+D G+Y +A+ G+A + ++ Sbjct: 8863 IVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELY 8922 Query: 1187 VDDAPASENTKAPEM-KSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP-PQIIQFP 1244 + K P++ SR P ++P ++ P + PP A P P ++ P Sbjct: 8923 LTTKEIKLELKPPDIPDSRVPIPTMP----------IRAVPPEEIPPVVAPPIPLLLPTP 8972 Query: 1245 EDQK 1248 E++K Sbjct: 8973 EEKK 8976 Score = 189 bits (480), Expect = 2e-47 Identities = 207/837 (24%), Positives = 323/837 (38%), Gaps = 133/837 (15%) Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85 S+ + E P F P + +GA E ++G P V+W+++ + + SG ++ + + Sbjct: 7392 SLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI---M 7448 Query: 86 RGTFSLVIHAVHEE--DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 F IH ++ + D G+Y C+ATN G+ T GS A + Sbjct: 7449 SENFLTSIHILNVDAADIGEYQCKATNDVGSD------TCVGSIALK------------- 7489 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202 PP+F KL + G+ + I G V W K + + Sbjct: 7490 ---------------APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVR 7534 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA---------------- 246 S + +S + L+ V + G YTC + N +G A Sbjct: 7535 ESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPES 7594 Query: 247 -----------ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSK 295 E ++ G + + ++ K SD + +++ +K S L + A Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKIS-FFNKVSGLKIINVAPSD- 7652 Query: 296 NCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE 355 S ++ Q ++S S + S RT P + +K + L + V E Sbjct: 7653 ---------SGVYSFEVQNPVGKDSCTASLQVSDRTVPPS-FTRKLKETNGLSGSSVVME 7702 Query: 356 PRAPGLGVLSPS----GEE----RKRPAPPRPATFPTRQPGL---GSQDVVSKAANRRIP 404 + G +S S G E RK T L S D A N Sbjct: 7703 CKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN---- 7758 Query: 405 MEGQRDSAFP-------KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457 M G + + P F KP +V V F V G P V+WF + + Sbjct: 7759 MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPG 7818 Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517 + ED+ + L L T SG Y+C SN G+ SC+ L ++ A F Sbjct: 7819 DRCNVSLEDSVAE-LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA------KFV 7871 Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDAL 574 L D ++ +G+ +L+ + GTP +TW NG P Q T A L I + Sbjct: 7872 KRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSST 7931 Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634 ED G Y C ENA G+ SCSA + + E P F++ L +KV Sbjct: 7932 VEDAGQYNCYIENASGKDSCSAQILILEP-------------------PYFVKQLEPVKV 7972 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694 G ++ Q++G P V W +++ + + R +L +V D+G Y Sbjct: 7973 SVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYI 8032 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 754 C+A NS GEV LTVQE P F + R V ++G V+ CAI+G +V W Sbjct: 8033 CKAENSVGEVSASTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSW 8090 Query: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 +DGK L KD+ + + ++ TL + K AGQY N +G S L+L Sbjct: 8091 YKDGKPL-KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146 Score = 188 bits (478), Expect = 4e-47 Identities = 216/961 (22%), Positives = 369/961 (38%), Gaps = 152/961 (15%) Query: 414 PKFESKPQ-SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472 P+F K + S+ VK+++ ++ C++ G P+ +V W+ + T ++ + D+ + L Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVA-VL 7363 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 + DSG Y+C A NA G S S +L+V+ + P LK G D Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK------GADVH 7417 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENAL 589 L+C ++GTP ++W + + ++ + E + +HI + D G Y C A N + Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G +C + + AP P F++ LSD+ + G +V + + G Sbjct: 7478 GSDTCVGSIALK--------------AP-----PRFVKKLSDISTVVGKEVQLQTTIEGA 7518 Query: 650 PPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708 P V+W + EI +ES++ +L V P + G YTC+ N AG A Sbjct: 7519 EPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA 7578 Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 768 L+V EP + KP S+ + G + + C +AG P + W +DGK L D + Sbjct: 7579 TLSVLEPAT-----IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDN-KY 7632 Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPA 826 ++ V L + V P +G Y ++N VG+ SC SL + S R +P R+ Sbjct: 7633 KISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV---SDRTVPPSFTRKLK 7689 Query: 827 SCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEA 886 L G V + YGS P W E G ++ K + +T A Sbjct: 7690 ETNGLSGSSVVME---CKVYGS-----PPISVSWFHE--GNEISSGRKYQTTLTDNT-CA 7738 Query: 887 IRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVH 946 + +E+ D D ++T D+ P TV E V Sbjct: 7739 LTVNMLEESDSGDY--TCIATNMAGSDECS-----------------APLTVREPPSFVQ 7779 Query: 947 SPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVL--GGKKKLPAENGSSSAETLN 1004 P +D VL + T + + PP + S L G + + E+ + E + Sbjct: 7780 KPDPMD---VLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFD 7836 Query: 1005 AKAVES-------SKPLSNAQPSGPLKPVGNAKPAETL--------KPM-------GNAK 1042 +S S A + L AK + L KP+ G Sbjct: 7837 VDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPP 7896 Query: 1043 PAETLKPMG-NAKPDE--NLKSASKEELKKDVKNDV------NCKRGHAGTTDNEKRSES 1093 + T K G N P + N+ + K + + + V NC +A D+ Sbjct: 7897 ISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQIL 7956 Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153 P F ++L+ V V+ G LQCQ++ P + W L+ T + ++ Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 8016 Query: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213 ++ + D G Y C A+N G+ S +TV + Sbjct: 8017 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE------------------------ 8052 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +PP + D + G V ++G++PI+ +W K Sbjct: 8053 --------------------QKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYK 8092 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 K +++S +++ +N + L I + G Y+ N +GS + L + + +P Sbjct: 8093 DGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP 8152 Query: 1334 P 1334 P Sbjct: 8153 P 8153 Score = 183 bits (465), Expect = 1e-45 Identities = 200/829 (24%), Positives = 321/829 (38%), Gaps = 119/829 (14%) Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83 VD P+F +N GA+ E +V G V W I SG ++ Sbjct: 5791 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKY---- 5846 Query: 84 GIRGTFS-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + TFS L ++++ D G YTC A N +G+ + LTV+ Sbjct: 5847 --QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE------------- 5891 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 PP F + + V G+ F+ I G P +V W +G Sbjct: 5892 ---------------------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS--- 255 L R ++ ++ + LE+ ++ G YTC+V N +G+AS + L ++ + Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLK 5990 Query: 256 --------ANRSFVRETKATNS-----DVRKEVTNVISKES-KLDSLEAAAKSKNCSSPQ 301 +S + E+ T + +K+ N+ + E + + E + +S + Sbjct: 5991 RLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTK 6050 Query: 302 RGGSPPWAANSQPQPPRE--SKLESCKDSPRTAPQ-TPVLQKTSSSITLQAARVQPEPRA 358 R ++ + + R+ L S + P + P+ S++LQ Sbjct: 6051 RDAG-QYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQC----QVAGT 6105 Query: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGL--------GSQDVVSKA------ANRRIP 404 P + V G+ + RP P F L S + KA A+ + Sbjct: 6106 PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTV 6165 Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464 Q P F + + E V C ++G +V W+ +G +R E + Sbjct: 6166 FRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF 6225 Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524 D L +L+ SG YSC+ASN G S S L + +P F Sbjct: 6226 VD-NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE---PKKSPFFDIKPVSID 6281 Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTY 581 VI G+ +C V G RITW + + I+ + TC L I D G Y Sbjct: 6282 VIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQY 6341 Query: 582 TCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-MDGSQV 640 TC A N +G+ CSA ++V E P F++ L KV G + Sbjct: 6342 TCQATNDVGKDMCSAQLSVKE-------------------PPKFVKKLEASKVAKQGESI 6382 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 + ++SG+P +V W N +E+ ES ++ + L I E ED+G Y CEA N Sbjct: 6383 QLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNG 6442 Query: 701 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760 G+ LTV+ P P F KP V A G V++ C I+G P V W++D K Sbjct: 6443 VGDASCSTALTVKAP-----PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ 6497 Query: 761 LCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQV 807 + +++ F++ +L + ++ G+Y N VG CSC V Sbjct: 6498 V-RNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 6545 Score = 183 bits (464), Expect = 2e-45 Identities = 195/836 (23%), Positives = 324/836 (38%), Gaps = 132/836 (15%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 + + E P+F+ P L + G F +RG P +V W R + + G R C I Sbjct: 5887 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDR----CNIY 5942 Query: 87 ---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 L + + G+YTC +N +G T L F K+ Sbjct: 5943 FEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRL-----FVKE------------- 5984 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 P F +L V+ G+ TG VTW K + Sbjct: 5985 ----------------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6028 Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA--------------------- 242 S + ++ +LEI + D G Y+C + N +G+ Sbjct: 6029 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPL 6088 Query: 243 ------SMSAELSIQGLDSANRSFVR-ETKATNS-DVRKEVTN-----VISKESKLDSLE 289 S+S + + G S+ + +TK + + R TN V +K + DS E Sbjct: 6089 EAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGE 6148 Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ-KTSSSITLQ 348 K++N S + + PP S KD +T L + + S +Q Sbjct: 6149 YTCKAEN-SIGTASSKTVFRIQERQLPP--SFARQLKDIEQTVGLPVTLTCRLNGSAPIQ 6205 Query: 349 AARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP---- 404 + GVL E + AT Q L S +A+ + Sbjct: 6206 VCWYRD-------GVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASS 6258 Query: 405 ---MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461 + + P F+ KP S +V ++ F C V+G + W + +R G+ Sbjct: 6259 SARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIR-PGGNY 6317 Query: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521 + + +L +LK DSG Y+C A+N G+ CS L V+ P F L+ Sbjct: 6318 TITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE------PPKFVKKLE 6371 Query: 522 DCAVI-EGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPE 576 V +G+ L+C + G+P +++W N + +Y S + VA L I +A E Sbjct: 6372 ASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINS-VALLTINEASAE 6430 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 D G Y C A N +G SCS +TV AP P+F Q S + + Sbjct: 6431 DSGDYICEAHNGVGDASCSTALTVK--------------AP-----PVFTQKPSPVGALK 6471 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 GS V + ++SG PP EV+W+ + +++ S+ F + SL I + D G Y C+ Sbjct: 6472 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 6531 Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 A N G + +EP P F+ K + +G +V + + G +V WL+ Sbjct: 6532 ATNEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLK 6586 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG--ECSCQVSLM 810 D + +++ + + +++ TL L + ++G+Y +KN G ECS ++++ Sbjct: 6587 DRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL 6642 Score = 176 bits (446), Expect = 2e-43 Identities = 181/789 (22%), Positives = 290/789 (36%), Gaps = 142/789 (17%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 M + AP L + G AKF ++ P + W + G+ I + C IR Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIR 3505 Query: 87 GT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 + SL I D G+YTC+A+N G+ T LTV ++ Sbjct: 3506 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY---------------- 3549 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 PP F ++ + G+ +F C +TG P + W K L P Sbjct: 3550 ----------------PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP 3593 Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263 S +S+ +LE+ + D GVY+C N G AEL I +D + F++E Sbjct: 3594 SPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII--IDKPH--FIKE 3649 Query: 264 TKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLE 323 + S + K+V E ++D R + W+ + Q PP + + Sbjct: 3650 LEPVQSAINKKV----HLECQVDE-------------DRKVTVTWSKDGQKLPPGKD-YK 3691 Query: 324 SCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP 383 C + + P+ + S G V + S E AT Sbjct: 3692 ICFEDKIATLEIPLAKLKDS----------------GTYVCTASNEAGSSSC---SATVT 3732 Query: 384 TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESK-PQSQEVKENQTVKFRCEVSGIPK 442 R+P P F K S + ++ + C++ G P Sbjct: 3733 VREP--------------------------PSFVKKVDPSYLMLPGESARLHCKLKGSPV 3766 Query: 443 PEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502 +V WF + + ++ +Y L + + DSG+YSC A N G SCS + Sbjct: 3767 IQVTWFKNNKEL-SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825 Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RS 559 V++ PSF L+ ++ G + +LQC V GT I+W + + I+ + R Sbjct: 3826 ------VIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL 3879 Query: 560 TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSK 619 + + L I D G Y C+ N +G+ C A + E Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE----------------- 3922 Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P F++ + DL + G VT+ V G+ P V W+ I+E Sbjct: 3923 --PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 3980 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 L I +V G YTC A N AG + L V+EP I + + + G Sbjct: 3981 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAK-----IIERAELIQVTAGDPAT 4035 Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799 + +AG P W +DG+ L + + + +V L + +GQY + N Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPLVA-SKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNE 4094 Query: 800 VGECSCQVS 808 VG SC+ + Sbjct: 4095 VGSSSCETT 4103 Score = 172 bits (437), Expect = 2e-42 Identities = 123/402 (30%), Positives = 180/402 (44%), Gaps = 34/402 (8%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F KPQSQ+V N V+ + V G + WF + + + V++D S L Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELH-SGAARSVWKDDTSTSLE 4826 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 L A+ DSGTY C SN G + TL V+ PS VL++ GQ Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRN-----GQSTTF 4881 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590 +C + GTP R++W L+G I + + G+A I A E+ GTY C A N G Sbjct: 4882 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 4941 Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650 SCS + V E P F++ L ++V+ S V + +V+G P Sbjct: 4942 TASCSIELKVKEP-------------------PTFIRELKPVEVVKYSDVELECEVTGTP 4982 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710 P EV WL N EI+ S+ + R + +L I + P DTG Y C N G + Sbjct: 4983 PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 5042 Query: 711 TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770 ++EP P FI K + T L S +AG P ++ WL+D + L +D + + Sbjct: 5043 ALKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVY-I 5096 Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 + V TL ++ V H+G+Y KN G C L++Q Sbjct: 5097 SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138 Score = 165 bits (417), Expect = 5e-40 Identities = 182/788 (23%), Positives = 302/788 (38%), Gaps = 136/788 (17%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E P+FI N ++A F+ V G P +TW ++ Q + + + Sbjct: 5044 LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSV 5102 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 +L I +V G+YTC+A N SG + L V+ Sbjct: 5103 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE----------------------- 5139 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 P + K V V E C + G P+ +V WLK + PS S Sbjct: 5140 -----------PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFS 5188 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268 +S +N + I V + D G YT V N G +S A L + + SF + K T Sbjct: 5189 MSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD-QNIPPSFTK--KLTK 5245 Query: 269 SDVRKEVTNVISKESKLD-SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327 D K + + I E K+ SL +A+ W + + C + Sbjct: 5246 MD--KVLGSSIHMECKVSGSLPISAQ--------------WFKDGKEISTSAKYRLVCHE 5289 Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387 + + + +++ T + + V + G+ + PP P RQ Sbjct: 5290 RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK---------EPPSFLVKPGRQQ 5340 Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447 + V KA + P F+ K F+ +V + P+ Sbjct: 5341 AIPDSTVEFKAILK----------GTPPFKIK------------WFKDDVELVSGPKCFI 5378 Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507 LEG+ + +L L +G Y+C +N G SC+ L V Sbjct: 5379 GLEGS----------------TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE- 5421 Query: 508 AVMEVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 563 P F L+ +++ G L+C + G+P R+ W N + + R T Sbjct: 5422 -----PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFID 5476 Query: 564 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 623 VA + + + ED G + C A+N G SCS V V E PV S P P Sbjct: 5477 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP----------PVFSSFP--P 5524 Query: 624 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 683 I ++ + ++V++ ++SG PP EV+W + +++ S+ + + S+ I Sbjct: 5525 I-------VETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHIL 5577 Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 743 V D G Y C+A N G + ++EP P F+SK S+T G+ + + Sbjct: 5578 NVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFVSKLNSLTVVAGEPAELQAS 5632 Query: 744 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 803 I G V WL++ + + +++ + + E+V TL K +P +AG+Y +KN G Sbjct: 5633 IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMR 5692 Query: 804 SCQVSLML 811 +LM+ Sbjct: 5693 ENMATLMV 5700 Score = 164 bits (416), Expect = 6e-40 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%) Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122 +VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++ Sbjct: 32748 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 32807 Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171 + S K+ Q T+ + A E S P T L Sbjct: 32808 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 32862 Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y Sbjct: 32863 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 32922 Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285 TC V N +G S S +L+I+ + V K + + V++E++ + ++ Sbjct: 32923 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 32982 Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 EA ++ SK S + S + +K + RT + Sbjct: 32983 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 33042 Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388 T SI + R+ + G GV + EE + T +Q Sbjct: 33043 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 33100 Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440 + + +SK + + + S P F S+P+SQ + E Q V F CE+SG Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 33160 Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS Sbjct: 33161 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 33217 Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560 T + L ++E PS VL+ D LQ S + Q +Q + S Sbjct: 33218 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 33259 Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613 EA + A + ++ ++ ++S S+++ + S + Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 33319 Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671 A + P SD+ + +G +T+ +G P PEV W G +I QE FH Sbjct: 33320 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 33379 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 E +L I +V +D G YT N G Sbjct: 33380 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 33410 Score = 163 bits (413), Expect = 1e-39 Identities = 181/791 (22%), Positives = 289/791 (36%), Gaps = 144/791 (18%) Query: 31 EAPAFILPPRN-LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89 E P FI P L ++ G + FE ++ G P+ +V+W+ +G IT+ + + I G Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDGLA 4917 Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149 + I E+ G Y CEA N +G ++EL V+ Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKE------------------------ 4953 Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 PP F +L V V + C++TG P +VTWLK N ++ S + ++ Sbjct: 4954 ----------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL 5003 Query: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269 +++ + L I + D G Y C+V N G S S ++++ SF+++ + T Sbjct: 5004 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK----EPPSFIKKIENT-- 5057 Query: 270 DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESC 325 T V+ + S A GSPP W + Q ++ S Sbjct: 5058 ------TTVLKSSATFQSTVA-------------GSPPISITWLKDDQILDEDDNVYISF 5098 Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385 DS T V S T QA + SG ER A + Sbjct: 5099 VDSVATLQIRSVDNGHSGRYTCQAK--------------NESGVERCY------AFLLVQ 5138 Query: 386 QPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEV 445 +P +V KA +S +V E + C V+G P+ +V Sbjct: 5139 EPA----QIVEKA----------------------KSVDVTEKDPMTLECVVAGTPELKV 5172 Query: 446 AWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505 W +G + +E+ + + + +DSG Y+ N G SC L Sbjct: 5173 KWLKDGKQIVPSRYFSMSFENNVASFR-IQSVMKQDSGQYTFKVENDFGSSSCDAYL--- 5228 Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCE 562 R+ + PSF+ L + G ++C V G+ W +G+ I + R C Sbjct: 5229 RVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288 Query: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622 L + + ED YTC N G +CS +TV E Sbjct: 5289 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-------------------P 5329 Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682 P FL + + S V + G PP ++ W + E+ G+ L + Sbjct: 5330 PSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNL 5389 Query: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLIS 741 V TG YTC N G +L V EP P F+ K S G S + Sbjct: 5390 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLE 5444 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 C IAG P V W R+ L + + + + V + + + +G + +N G Sbjct: 5445 CKIAGSPEIRVVWFRNEHEL-PASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 5503 Query: 802 ECSCQVSLMLQ 812 SC ++++ Sbjct: 5504 STSCSTKVIVK 5514 Score = 159 bits (402), Expect = 2e-38 Identities = 114/408 (27%), Positives = 182/408 (44%), Gaps = 16/408 (3%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P+ + Q V+ + +F +SG P+P+++W+ E + + D + L Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3297 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526 L++A D+ Y+C A N G + S +L VE V+ P+ + L+D Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357 Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583 EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416 Query: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643 +A NA+GQVS +A +++ +S + AP+ + + L+V G T Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFT 3476 Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703 ++ P W G EI ES+ SL I D G YTC+A N G Sbjct: 3477 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 3536 Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763 V A LTV E + P F+S+P+S+T +G++ C + G P W +DG AL Sbjct: 3537 VSCTATLTVTEAY---PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAAL-S 3592 Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 + ++ + E+ L L + G Y N+ G CQ L++ Sbjct: 3593 PSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII 3640 Score = 156 bits (395), Expect = 2e-37 Identities = 172/788 (21%), Positives = 296/788 (37%), Gaps = 148/788 (18%) Query: 29 LTEAPAFILP-PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 +TE P F+ + +K G +++ E ++ G PE +V W RN + + ++ + I Sbjct: 5419 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDS 5477 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 + ++ + ED G + CEA N +G+ + ++ V+ Sbjct: 5478 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK----------------------- 5514 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 P ++ PP T +K ++ C+++G P +V W K L+ S + Sbjct: 5515 ----EPPVFSSFPPIVET------LKNAEVS-LECELSGTPPFEVVWYKDKRQLRSSKKY 5563 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267 ++ KN + I V+ D+G Y C N G + + + Sbjct: 5564 KIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL----------------- 5606 Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP---PWAANSQPQPPRESKLES 324 KE +SK + L + A + + G P W + K E Sbjct: 5607 -----KEPPRFVSKLNSLTVV--AGEPAELQASIEGAQPIFVQWL---------KEKEEV 5650 Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384 ++S + + TLQ A+ +P + + G R+ AT Sbjct: 5651 IRESENIR-----ITFVENVATLQFAKAEPANAGKYICQIKNDGGMRE-----NMATLMV 5700 Query: 385 RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPE 444 +P + +V KA PM V +T C+V+G P+ Sbjct: 5701 LEPAV----IVEKAG----PM------------------TVTVGETCTLECKVAGTPELS 5734 Query: 445 VAWFLEGTPV-RRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ 503 V W+ +G + Q+ Y S L +L +D+GTY+ N G+ SC+ + Sbjct: 5735 VEWYKDGKLLTSSQKHKFSFYNKISS--LRILSVERQDAGTYTFQVQNNVGKSSCTAVVD 5792 Query: 504 VERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW------LLNGQPIQYA 557 V A V PSF+ LK+ + G +L+C V G+ + W +++G Q Sbjct: 5793 VSDRA---VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQ-- 5847 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 +T V L + D G YTC+A N G C A +TV E Sbjct: 5848 -TTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE--------------- 5891 Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677 P F++ L+V+ G VT T + G PP +V W E+ + + + T Sbjct: 5892 ----PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTV 5947 Query: 678 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737 L + + +G YTC N+AG+ L V+EP F+ + + G+S Sbjct: 5948 AELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP-----AAFLKRLSDHSVEPGKS 6002 Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797 +++ G +V W +DG + + ++ E L + AGQY ++ Sbjct: 6003 IILESTYTGTLPISVTWKKDGFNI-TTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6061 Query: 798 NRVGECSC 805 N G C Sbjct: 6062 NEAGRDVC 6069 Score = 152 bits (384), Expect = 3e-36 Identities = 153/659 (23%), Positives = 252/659 (38%), Gaps = 74/659 (11%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PP+ +L V V+ G+ RF I+GRPQP+++W K L + L Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 + +D VYTC N G A+ SA LS++ V E + + ++ +I Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVSPDQEMPVYPPAII 3348 Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVL 338 + + E C W + + +P R ++ +D+ + Sbjct: 3349 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ-------- 3400 Query: 339 QKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKA 398 L+ A PE V S + + A P + ++ + Sbjct: 3401 --------LEIAEAYPEDEGTYTFVASNAVGQVSSTA-----NLSLEAP----ESILHER 3443 Query: 399 ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE 458 + I ME + A P + K + EV KF CE+ P WF G + + Sbjct: 3444 IEQEIEMEMK---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESD 3500 Query: 459 GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518 + L +L+ + D G Y+C ASN G +SC+ TL V P+F S Sbjct: 3501 -KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE----AYPPTFLS 3555 Query: 519 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI---QDALP 575 K G+ C+V GTPV W +G + + + + HI + Sbjct: 3556 RPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTI 3615 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 +D G Y+C A N G C A + + +K P F++ L ++ Sbjct: 3616 QDRGVYSCKASNKFGADICQAELIIIDK-------------------PHFIKELEPVQSA 3656 Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695 +V + QV + V W +G ++ +D+ +L I +D+GTY C Sbjct: 3657 INKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVC 3716 Query: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHW 754 A N AG A +TV+EP P F+ K S G+S + C + G P V W Sbjct: 3717 TASNEAGSSSCSATVTVREP-----PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTW 3771 Query: 755 LRDGKALCK-DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 ++ K L + +T + +E + + KV+ +G Y N VG SC ++++ Sbjct: 3772 FKNNKELSESNTVRMYFVNSEAILDITDVKVE--DSGSYSCEAVNDVGSDSCSTEIVIK 3828 Score = 150 bits (378), Expect = 2e-35 Identities = 184/788 (23%), Positives = 286/788 (36%), Gaps = 141/788 (17%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91 AP F P RN+ T + + ++ G +V+W ++G+ I + R+ + + GT SL Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRI-AFVEGTASL 4170 Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151 I V D G +TC ATN G++ + L V+ Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204 Query: 152 RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211 PP F TK G V G G + W KGN L +++ Sbjct: 4205 --------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITK 4256 Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271 + LE++ V D G YTC V N +G SA L ++ +FV + + + Sbjct: 4257 EALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK----EPATFVEKLEPSQLLK 4312 Query: 272 RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKD 327 + + T + K + G+PP W AN RE K ES K Sbjct: 4313 KGDATQLACKVT--------------------GTPPIKITWFAND-----REIK-ESSKH 4346 Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387 T VL+ T I SGE Q Sbjct: 4347 RMSFVESTAVLRLTDVGI-------------------EDSGE-----------YMCEAQN 4376 Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447 GS S + P F K E KP EV + V EV+G P E+ W Sbjct: 4377 EAGSDHCSSIVIVKESPY-------FTK-EFKP--IEVLKEYDVMLLAEVAGTPPFEITW 4426 Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507 F + T + R + + L +LK D+G Y C +N G CS R+ Sbjct: 4427 FKDNT-ILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS-----ARV 4480 Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAG 564 + E PSF ++ + + G Q +++G+ +TWL + I R T E Sbjct: 4481 TLRE-PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 4539 Query: 565 VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 VA L++ + G Y C A+N G CSA ++V K A I Sbjct: 4540 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV------------------KEPATI 4581 Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684 + +S + V G T+ V+ SG W +G E+ + T L I Sbjct: 4582 TEEAVS-IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIIS 4640 Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744 +D+G YT E N G +A + V + P F K + + + G + + C + Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDLI--IPPSFTKKLKKMDSIKGSFIDLECIV 4698 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 AG ++ W +D + + + + F L + +++ +G Y N+ G Sbjct: 4699 AGSHPISIQWFKDDQEISASEKYKFSFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQ 4757 Query: 805 CQVSLMLQ 812 C L ++ Sbjct: 4758 CSGHLTVK 4765 Score = 149 bits (375), Expect = 3e-35 Identities = 114/402 (28%), Positives = 173/402 (43%), Gaps = 34/402 (8%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P FE P S EV ++ F + G P +V WF + E ED + L Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTE-LE 6892 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 L + + +SG YSC +N G SC+ L V+ A +F L D +V G VL Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA------TFVKRLADFSVETGSPIVL 6946 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALPEDHGTYTCLAENAL 589 + + GTP ++W+ + I + C + E L I ++ ED+ Y+CL EN Sbjct: 6947 EATYTGTPPISVSWIKDEYLISQSER-CSITMTEKSTILEILESTIEDYAQYSCLIENEA 7005 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 GQ C A V+V E P F++ L ++ + G T+ +V G Sbjct: 7006 GQDICEALVSVLEP-------------------PYFIEPLEHVEAVIGEPATLQCKVDGT 7046 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P + W +++ + + + + SL I +V D G Y+C+A NS G V + AV Sbjct: 7047 PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAV 7106 Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 L ++ P+F K + V +LG V C I G V W +DG L KD + + Sbjct: 7107 LVIKARK--LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG-VLLKDDANLQ 7163 Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 +V TL + + H GQY N +G S L+L Sbjct: 7164 TSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL 7205 Score = 143 bits (360), Expect = 2e-33 Identities = 101/400 (25%), Positives = 178/400 (44%), Gaps = 35/400 (8%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F+ KP S ++ ++ F+C V+G ++ W + +R G+ ++ + L Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIR-PGGNYKMTLVENTATLT 7270 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV- 532 +LK D+G Y+C ASN G+ SCS L V+ P F L+ +++ +F Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE------PPRFIKKLEPSRIVKQDEFTR 7324 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 +C + G+P ++ W + IQ + R + VA L + + ED G YTC A NA Sbjct: 7325 YECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA 7384 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G S S + V E PIF + ++ + G+ V + ++ G Sbjct: 7385 GSASSSTSLKVKEP-------------------PIFRKKPHPIETLKGADVHLECELQGT 7425 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 PP V W + E++ + + S+ I V D G Y C+A N G Sbjct: 7426 PPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGS 7485 Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 + ++ P P F+ K ++ +G+ V + I G +V W +D + +++ + Sbjct: 7486 IALKAP-----PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIW 7540 Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 + +E++ TL +V+P +AG+Y +KN G C +L Sbjct: 7541 ISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATL 7580 Score = 141 bits (356), Expect = 5e-33 Identities = 118/449 (26%), Positives = 181/449 (40%), Gaps = 52/449 (11%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F S+P+S + KF C V+G P E W +G + + + + H L Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSP-NWRISDAENKHILE 3609 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 L +D G YSC ASN G C Q E + + + P F L+ + L Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADIC----QAELIIIDK--PHFIKELEPVQSAINKKVHL 3663 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590 +C V +TW +GQ + + E +A L I A +D GTY C A N G Sbjct: 3664 ECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAG 3723 Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650 SCSA VTV E S ++ V PS P G + ++ G+P Sbjct: 3724 SSSCSATVTVREPPS-----FVKKVDPSYLMLP-------------GESARLHCKLKGSP 3765 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710 +V W N E+ ES ++ L I +V ED+G+Y+CEA N G + Sbjct: 3766 VIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825 Query: 711 TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770 ++EP P FI G + L+ C ++G + W +D K + + + + + Sbjct: 3826 VIKEP-----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI-RSSKKYRL 3879 Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML------------------Q 812 + + L + G+YE ++ N VG+C C + +L Q Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQ 3939 Query: 813 NSSARALPRGREPASCEDLCGGGVGADGG 841 + +A RG EP S + G V + G Sbjct: 3940 TVTLQAAVRGSEPISVTWMKGQEVIREDG 3968 Score = 140 bits (353), Expect = 1e-32 Identities = 165/790 (20%), Positives = 277/790 (35%), Gaps = 139/790 (17%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 + + E P FI + + + + + + E V G P +VTW +N + I S ++ L + Sbjct: 4949 LKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV- 5007 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146 F+L I D G+Y C +N G+ + + ++ Sbjct: 5008 SVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE--------------------- 5046 Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206 PP F K+ F + G P +TWLK + L Sbjct: 5047 -------------PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 5093 Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266 V +S + + L+I V+ G YTC N SG A L +Q Sbjct: 5094 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ--------------- 5138 Query: 267 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326 E ++ K +D E + C G+P E K++ K Sbjct: 5139 -------EPAQIVEKAKSVDVTEKDPMTLECVV---AGTP------------ELKVKWLK 5176 Query: 327 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386 D + P +++ + R+Q + SG+ TF Sbjct: 5177 DGKQIVPSRYFSMSFENNVA--SFRIQSVMK-------QDSGQ----------YTFKVEN 5217 Query: 387 P-GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEV 445 G S D + ++ IP P F K + ++ C+VSG Sbjct: 5218 DFGSSSCDAYLRVLDQNIP---------PSFTKKLTKMDKVLGSSIHMECKVSGSLPISA 5268 Query: 446 AWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505 WF +G + V + S L + D+ Y+C SN G +CS L V+ Sbjct: 5269 QWFKDGKEISTSAKYRLVCHER-SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327 Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CE 562 V P + D V + ++GTP +I W + + E Sbjct: 5328 EPPSFLVKPGRQQAIPDSTV------EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLE 5381 Query: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622 + L++ G YTC N +G SC+ + V E Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE-------------------P 5422 Query: 623 PIFLQGLSDLKVMD-GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 P F++ L K++ G + +++G+P V+W N +E+ S+ + + + Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 + + ED+G + CEA N AG + V+EP P F S P V V + Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP-----PVFSSFPPIVETLKNAEVSLE 5537 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 C ++G P V W +D + L + + +++ ++ + V G+Y +N VG Sbjct: 5538 CELSGTPPFEVVWYKDKRQL-RSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 5596 Query: 802 E--CSCQVSL 809 C C V L Sbjct: 5597 SDTCVCTVKL 5606 Score = 137 bits (345), Expect = 1e-31 Identities = 113/395 (28%), Positives = 167/395 (42%), Gaps = 50/395 (12%) Query: 435 CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS---GTYSCTASN 491 C+V+G VAWF E T + S Y+ S +C L+ + DS G Y+C A+N Sbjct: 5821 CKVAGSSPISVAWFHEKTKIV----SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN 5876 Query: 492 AQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551 G C L V+ PSF + V+ G++ +RGTP ++ W Sbjct: 5877 VAGSDECRAVLTVQE------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930 Query: 552 QPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608 + + E VAEL + + G YTC+ N GQ SC+ + V E Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE------ 5984 Query: 609 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668 P A FL+ LSD V G + + +G P V W +G I SE Sbjct: 5985 -----------PAA--FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEK 6031 Query: 669 FHFEQRGTQHSLCIQEVF---PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725 + T CI E+ D G Y+CE N AG A+++ EP P+F++ Sbjct: 6032 CNIV---TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP-----PYFVT 6083 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785 + + A++G SV + C +AG P TV W + G + T + +V TLV KV Sbjct: 6084 ELEPLEAAVGDSVSLQCQVAGTPEITVSWYK-GDTKLRPTPEYRTYFTNNVATLVFNKVN 6142 Query: 786 PWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820 +G+Y +N +G S + +Q R LP Sbjct: 6143 INDSGEYTCKAENSIGTASSKTVFRIQE---RQLP 6174 Score = 136 bits (343), Expect = 2e-31 Identities = 107/403 (26%), Positives = 170/403 (42%), Gaps = 30/403 (7%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F ++ + E +V +C+V+G P+ V+W+ +G R Y L Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWY-KGDTKLRPTPEYRTYFTNNVATLV 6137 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 K DSG Y+C A N+ G S +++ ++ PSF+ LKD G L Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTASSKTVFRIQE---RQLPPSFARQLKDIEQTVGLPVTL 6194 Query: 534 QCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590 C + G+ ++ W +G + + +++ VA L I G Y+C A N LG Sbjct: 6195 TCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLG 6254 Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650 S SA +T E K S P KP + + V+ G V+G Sbjct: 6255 TASSSARLTAREPKKS-------PFFDIKPVS---------IDVIAGESADFECHVTGAQ 6298 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710 P + W + EI+ ++ G L I +V D+G YTC+A N G+ A L Sbjct: 6299 PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358 Query: 711 TVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 +V+EP P F+ K S A G+S+ + C I+G P V W R+ L ++ + Sbjct: 6359 SVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSEL-HESWKYN 6412 Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 + V L + + +G Y N VG+ SC +L ++ Sbjct: 6413 MSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455 Score = 136 bits (342), Expect = 2e-31 Identities = 119/403 (29%), Positives = 165/403 (40%), Gaps = 33/403 (8%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P+F K V+ R V G V W + V R+ + + L Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ 6610 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 L +SG Y C N G CS L V A + P + V G F L Sbjct: 6611 LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP------EPMTVTTGNPFAL 6664 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590 +C V GTP W +G+ + T VA L I A D G Y+ +N++G Sbjct: 6665 ECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724 Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650 + +C+ V+VH S+ ++P P F++ L D+ + G+ V + +VSG+ Sbjct: 6725 KSNCT--VSVHV------SDRIVP--------PSFIRKLKDVNAILGASVVLECRVSGSA 6768 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710 P V W +GNEI +L + + P DTG YTC A N AG AVL Sbjct: 6769 PISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 6828 Query: 711 TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770 TVQEP P F P SV G S+ + I G P V W + + L G Sbjct: 6829 TVQEP-----PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELV--PGESCN 6881 Query: 771 LQNEDVFT-LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 + ED T L L +VQP +G Y L+ N G SC L ++ Sbjct: 6882 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924 Score = 134 bits (336), Expect = 1e-30 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%) Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 S + P + S+ P + Q V + KF + +G P+P W +G + Sbjct: 32834 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 32893 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++ Sbjct: 32894 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 32942 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 +KD E Q Q + TP + ++ + Q A + E ++E Q+ L Sbjct: 32943 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 32994 Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631 ++ + ++E + S + VHE+ K+S+ SE + A K + + Sbjct: 32995 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 33047 Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G Sbjct: 33048 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 33105 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751 TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 33164 Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 + W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+ Sbjct: 33165 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223 Query: 812 QNSSARALPRGREPA 826 LP EP+ Sbjct: 33224 -------LPLVEEPS 33231 Score = 130 bits (327), Expect = 1e-29 Identities = 102/386 (26%), Positives = 168/386 (43%), Gaps = 33/386 (8%) Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490 V F C ++G +V+W+ +G + + + +++ L +L+ G Y+C+AS Sbjct: 7133 VAFECRINGSEPLQVSWYKDGV-LLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSAS 7191 Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 550 N G S S L L+ EV P F + G+ +C V GT +ITW + Sbjct: 7192 NPLGTASSSAKLI---LSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKD 7248 Query: 551 GQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607 + I+ + T A L + D G YTC A N G+ SCSA + V E Sbjct: 7249 NREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEP---- 7304 Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM-TVQVSGNPPPEVIWLHNGNEIQES 666 P F++ L +++ + T ++ G+P +V+W + EIQES Sbjct: 7305 ---------------PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES 7349 Query: 667 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 726 F + L + + ED+G YTCEA N+AG + L V+EP P F K Sbjct: 7350 SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP-----PIFRKK 7404 Query: 727 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQP 786 P + G V + C + G P V W +D + L + ++++ + ++ + V Sbjct: 7405 PHPIETLKGADVHLECELQGTPPFHVSWYKDKREL-RSGKKYKIMSENFLTSIHILNVDA 7463 Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQ 812 G+Y+ N VG +C S+ L+ Sbjct: 7464 ADIGEYQCKATNDVGSDTCVGSIALK 7489 Score = 129 bits (325), Expect = 2e-29 Identities = 105/407 (25%), Positives = 168/407 (41%), Gaps = 33/407 (8%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P+F SK S V + + + + G V W E V R+ +I + L Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQ 5669 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 KA ++G Y C N G TL V E ++E A + V G+ Sbjct: 5670 FAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMT-------VTVGETCT 5722 Query: 533 LQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 L+C V GTP + W +G+ + Q + + ++ L I +D GTYT +N + Sbjct: 5723 LECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 5782 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G+ SC+A V V ++ P F + L + + G+ + +V+G+ Sbjct: 5783 GKSSCTAVVDVSDRA----------------VPPSFTRRLKNTGGVLGASCILECKVAGS 5826 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P V W H +I + +L + + D G YTC A N AG +AV Sbjct: 5827 SPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886 Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 LTVQEP P F+ +P + G++V + I G P V+W R + L K Sbjct: 5887 LTVQEP-----PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCN 5940 Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 + + V L L + +G+Y ++ N G+ SC L ++ +A Sbjct: 5941 IYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA 5987 Score = 125 bits (314), Expect = 4e-28 Identities = 107/395 (27%), Positives = 171/395 (43%), Gaps = 37/395 (9%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKARTRDSG 483 V+ + +G P V+W + + + E SI + E S L +L++ D Sbjct: 6938 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEK--STILEILESTIEDYA 6995 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 YSC N GQ C E L + P F L+ + G+ LQC V GTP Sbjct: 6996 QYSCLIENEAGQDIC------EALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI 7049 Query: 544 RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 RI+W ++ A + + VA L I D G Y+C A+N++G V+ SA + + Sbjct: 7050 RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 7109 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 +K LP P F + L D+ G V +++G+ P +V W +G Sbjct: 7110 KARK--------LP--------PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG 7153 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPED---TGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 +++ + Q H++ ++ D G Y C A N G + A L + E H+ Sbjct: 7154 VLLKDDANL---QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSE-HE 7209 Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777 P+F KP SV +LG+S C + G + W +D + + + G++++ E+ Sbjct: 7210 -VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREI-RPGGNYKMTLVENTA 7267 Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 TL + KV AGQY N G+ SC L +Q Sbjct: 7268 TLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302 Score = 122 bits (306), Expect = 3e-27 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++ Sbjct: 30151 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 30207 Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848 +L+N+ G+ + + + + S P G P +D+ V AD GG+D G Sbjct: 30208 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 30263 Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906 + W + VRG +++ E R Q L + V+ Sbjct: 30264 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 30321 Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963 KT L+ + P E +D + + + +V + ++ + K + Sbjct: 30322 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 30380 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022 KT + + PD + ++ A+N +ET A + V P G Sbjct: 30381 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 30436 Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070 L+ + +K + TL KP K D K ++KE +K Sbjct: 30437 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 30496 Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120 +N+ R T + K + G AP +++++DV G+ L CQ Sbjct: 30497 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 30555 Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180 + P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E Sbjct: 30556 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 30615 Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240 S ++ + P P P K Sbjct: 30616 TSSKLLLQATPQFH---------------------------------PGYPLK------- 30635 Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299 E G ++ L G TW +K +Q SE++ +EN+E+ + L + Sbjct: 30636 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 30691 Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG Sbjct: 30692 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 30751 Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P + Sbjct: 30752 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 30811 Query: 1418 ESELTTVGEKPEEP 1431 S + + E+P Sbjct: 30812 VSSVVIIKSPFEKP 30825 Score = 121 bits (303), Expect = 7e-27 Identities = 105/406 (25%), Positives = 179/406 (44%), Gaps = 37/406 (9%) Query: 409 RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAG 468 RD A P F ++ + N T + C+++G V+WF +G + + + + G Sbjct: 4109 RDIA-PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-G 4166 Query: 469 SHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEG 528 + L +++ D+G ++C A+N+ G S L +++ PSF + V+ G Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL------IVQEPPSFVTKPGSKDVLPG 4220 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLA 585 L+ + +G+ I W + + S T EA + L + D GTYTC Sbjct: 4221 SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKV 4280 Query: 586 ENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQ 645 N G V CSA + V E + ++ + PS+ LK D +Q + + Sbjct: 4281 SNVAGGVECSANLFVKEPAT-----FVEKLEPSQL-----------LKKGDATQ--LACK 4322 Query: 646 VSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705 V+G PP ++ W N EI+ES + L + +V ED+G Y CEA N AG Sbjct: 4323 VTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDH 4382 Query: 706 TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765 +++ V+E P+F + + + V++ +AG P + W +D L Sbjct: 4383 CSSIVIVKE-----SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGR 4437 Query: 766 GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809 + +Q+ V +LK V AG+Y+ + N VG CS +V+L Sbjct: 4438 KYKTFIQDHLVSLQILKFVAA-DAGEYQCRVTNEVGSSICSARVTL 4482 Score = 118 bits (295), Expect = 6e-26 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%) Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680 T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000 Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714 I+E F ED+G +TC A N AG V T L VQ Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060 Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759 P + P+FI+KP G SV+ C + G+P P V+W + G Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120 Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ + Sbjct: 1121 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177 Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875 L + ++ + V + G PG+ + + E+E + + K Sbjct: 1178 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1232 Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932 V R + E+ QE F + L K++ KT E+ L+E E+M + Sbjct: 1233 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1288 Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981 V+ S + ++ + + ++ V S P+P +++ + DF Sbjct: 1289 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344 Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035 R+ L LP + G +A N K NA SG P P+G TL Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1396 Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095 +P+ + +L P ++ + A + + + S+ + Sbjct: 1397 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1453 Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152 P F K EG+ +V P W +G+ + T +++ ++G+ Sbjct: 1454 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1513 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212 S+ I A P D G + VA+N AG++ S +TV+ Sbjct: 1514 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1550 Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272 + + P ++ ++ ++ G +E+ + TG W+ Sbjct: 1551 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1590 Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327 K I ++ +++E ++ + L I + + YT NK G + + +VN+ V Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650 Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348 +P+P P GT A +I + L Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPEL 1677 Score = 117 bits (294), Expect = 8e-26 Identities = 105/405 (25%), Positives = 166/405 (40%), Gaps = 38/405 (9%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED-AGSHYL 472 P F K +S T F+ + G V W + + + +E+ S YL Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA-VMEVAPSFSSVLKDCAVIEGQDF 531 ++ + G Y C A N G CS L V+ A + E A S V +G Sbjct: 4546 SGIEVK--HDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSID-------VTQGDPA 4596 Query: 532 VLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587 LQ GT W +GQ + +Y S + V+ L I +D G YT +N Sbjct: 4597 TLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDT-VSILKIISTEKKDSGEYTFEVQN 4655 Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647 +G+ SC A + V + ++P P F + L + + GS + + V+ Sbjct: 4656 DVGRSSCKARINV--------LDLIIP--------PSFTKKLKKMDSIKGSFIDLECIVA 4699 Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707 G+ P + W + EI SE + F L I ++ D+GTYTC A N AG + Sbjct: 4700 GSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS 4759 Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 LTV+EP P+F+ KP+S + V + + G T+ W +D K L Sbjct: 4760 GHLTVKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 4814 Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 V +++ +L L + +G Y L N VG + + +L ++ Sbjct: 4815 -SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858 Score = 115 bits (289), Expect = 3e-25 Identities = 104/403 (25%), Positives = 159/403 (39%), Gaps = 34/403 (8%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F K QTV + V G V W ++G V R++G I++ G L Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFSNGVAVLI 3982 Query: 474 LLKARTRDSGTYSCTASNAQG-QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 + + G Y+C A N G Q S + E ++E A V G Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-------VTAGDPAT 4035 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 L+ +V GTP + W +G+P+ + R + + VA+L A D G YT N + Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 4095 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G SC TV ++ AP F + L ++ + + +++G+ Sbjct: 4096 GSSSCETTFTVLDRD----------------IAPFFTKPLRNVDSVVNGTCRLDCKIAGS 4139 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P V W +G EI S+ + SL I V D G +TC A NS G + Sbjct: 4140 LPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGA 4199 Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 L VQEP P F++KP S G +V + G T+ W + K L G Sbjct: 4200 LIVQEP-----PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSG-GSCY 4253 Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 + + +L L V+ +G Y + N G C +L ++ Sbjct: 4254 ITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296 Score = 115 bits (288), Expect = 4e-25 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483 + E Q + + ++G +V W L G + E Y +GS +K A RD G Sbjct: 33050 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 33105 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 +C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 33163 Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 I W N PI + + V L I++A D G YT A+N GQ S +A + V Sbjct: 33164 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 LP+ +P+ + L+ D + GS + +VQ+S + + Sbjct: 33224 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 33269 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 + + F Q +QE F E + + N ++ + ++ G Sbjct: 33270 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 33328 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779 P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL Sbjct: 33329 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 33388 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813 ++ VQ G Y + L N G S V++ +++ Sbjct: 33389 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 33422 Score = 115 bits (287), Expect = 5e-25 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%) Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222 F +++ + EG F CK++G P P++ W K R+ E+ M L+ Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1343 Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282 G+AS+ + + + +F K N I Sbjct: 1344 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1376 Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342 KL +E AA G+P + +P S++ S SPR+ ++P+ Sbjct: 1377 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1415 Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402 R+ P +P R PA PA PG ++ R Sbjct: 1416 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1454 Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 P F KP S + E QT +F +V G P PE WF +G + Sbjct: 1455 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1505 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522 V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+ Sbjct: 1506 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1564 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577 + EG ++ G P P I WL N P +Y + E G A L I + +D Sbjct: 1565 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1624 Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617 YT A N G+ C V V + + + ++P AP Sbjct: 1625 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1684 Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662 K P F + L+ L++ +++ G+P V WLH+G Sbjct: 1685 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714 ++ + SL + D+G TC A N G T A L V++ Sbjct: 1745 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1804 Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744 H+G +P + P V G++ C + Sbjct: 1805 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1864 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G Sbjct: 1865 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1922 Query: 805 CQVSLMLQNSS--ARALPRGREP 825 +V L +Q L R EP Sbjct: 1923 HKVKLEIQQREDFRSVLRRAPEP 1945 Score = 113 bits (282), Expect = 2e-24 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 +K S RK E L + AP + +V G + V P EV W HNG Sbjct: 32353 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 32412 Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682 E+QES D H + GT ++C Sbjct: 32413 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 32472 Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718 + VFPE T T EA +S EV++Q T + H Sbjct: 32473 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 32532 Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752 + ++KPRS+T G+S SC G+P PTV Sbjct: 32533 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q Sbjct: 32593 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651 Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848 + + ++ R + P +++ Sbjct: 32652 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 32711 Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 L P + +L+ E +++ VL+ + T + +++ Q + Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771 Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954 ++ L+E D + EI E + NLQ + K++ E+ K+ ++ D + Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831 Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983 S + +K K P P P P+P T D ++ Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891 Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015 + GGK KL + G SS+ L KA++ ++ Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 32951 Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067 + Q + + P A E + A +E +K M AK E L + ASK EE+ Sbjct: 32952 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 33008 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 KK + H T + SE T K + + EG++L+L+ ++ Sbjct: 33009 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 33066 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W LNG L ++ GS +++I++A D G+ C++K G +C +T+ Sbjct: 33067 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247 + E+ SDA P I P Q Sbjct: 33127 ----------SKEL----------------SDA-----------------PAFISQPRSQ 33143 Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 + G++V +++G W K I S ++ + S N L I A G Sbjct: 33144 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 33203 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S Sbjct: 33204 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 33263 Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423 + S++ + + + S + Q + E + + + G S +Q S++ Sbjct: 33264 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 33321 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447 G + PK E SD E +V Sbjct: 33322 AGIRGIPPKIEALPSDISIDEGKV 33345 Score = 112 bits (279), Expect = 5e-24 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99 +N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E Sbjct: 1298 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1357 Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155 D G YT A+N G + +L VE A LG P TL R +P +R I Sbjct: 1358 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1415 Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179 P F K EGQ R Sbjct: 1416 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1475 Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238 F K+ GRP P+ W G + V +++G Q L I D G +T + N Sbjct: 1476 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1535 Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297 +G++S+S L+++ ++ FV + K N I + S+L+ A + N Sbjct: 1536 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1584 Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339 W NS P + ++E K + V Q Sbjct: 1585 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1638 Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395 T + ++ +PEP ++ P G R K A P P Q D+ Sbjct: 1639 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453 K ++ P F+ K S +K F C ++ G P V W +G P Sbjct: 1696 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744 Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502 + + + + G L A +RDSG +C A+N G S TL Sbjct: 1745 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1803 Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536 ++E L M + + V D V+EG+ +C Sbjct: 1804 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1863 Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594 V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G + Sbjct: 1864 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1923 Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + + +++ R +L AP +P + G +V + T + E Sbjct: 1924 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1975 Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694 V+ L I +ESE+ F++R + S E + E Sbjct: 1976 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 2035 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738 E + E+ + + E T P F + +S T G Sbjct: 2036 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2095 Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798 + G P P W ++G + + + ++V LV++ V + + N Sbjct: 2096 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2155 Query: 799 RVGECSCQVSLMLQ 812 GE S L++Q Sbjct: 2156 IAGETSSHAFLLVQ 2169 Score = 111 bits (278), Expect = 6e-24 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 +PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L Sbjct: 18898 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 18956 Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355 I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+ Sbjct: 18957 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 19016 Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE Sbjct: 19017 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 19076 Query: 1415 PSQESELTTVGE--KPEEPKD 1433 P ++ P EPK+ Sbjct: 19077 PLTSPKMVAQFPFGVPSEPKN 19097 Score = 110 bits (275), Expect = 1e-23 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567 AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+ Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I + G Y+ A N GQ + +A + V K+E AP P F+Q Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168 Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713 ED+GTY+ A NS G + A L VQ Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 109 bits (272), Expect = 3e-23 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%) Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89 T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58 Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144 S L I AV + + G+Y+ +ATNGSG T EL V+ A Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PP F +L + V++G R ++TG P P V + + +Q S Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252 +S++ + L I +D G Y+ N G+A+ +AEL +QG Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207 Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + +A S R+T+ + + ++ + E +D AA + +P R PP + Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263 Query: 312 SQPQPP 317 P PP Sbjct: 264 RSPTPP 269 Score = 109 bits (272), Expect = 3e-23 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 13761 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y + Sbjct: 13762 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 13820 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426 E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T + Sbjct: 13821 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 13880 Query: 1427 KPEEPKDEVEVSD 1439 P P +E SD Sbjct: 13881 DPPGPPTRLEPSD 13893 Score = 105 bits (262), Expect = 4e-22 Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%) Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 +F + +V E + F CEVS P V W + ++ + I++ ++ H L + Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3116 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 R D+G Y+ A + +L V S+ K+ VIE Q V++ Sbjct: 3117 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3167 Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 V V W +G I + + E + + I + D G YT +A Sbjct: 3168 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3224 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 +R S L AP P LQ L + V G +SG Sbjct: 3225 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3265 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P P++ W + F G +++L + E FPED YTCEA N G T A Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325 Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 L+V+ P D P + I+ + S GQ C ++G + +D K Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3383 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 K + F + Q ED + L + + P G Y + N VG+ S +L L+ Sbjct: 3384 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434 Score = 102 bits (253), Expect = 5e-21 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 +++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A Sbjct: 26876 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 26935 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG Sbjct: 26936 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 26995 Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 + + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP Sbjct: 26996 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 27052 Query: 1417 QESEL 1421 + + Sbjct: 27053 ESDSV 27057 Score = 101 bits (252), Expect = 6e-21 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%) Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292 +PP + ++ E V+AG +V + G T W +I+ EH VE Sbjct: 17506 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 17565 Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352 S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 17625 Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411 DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G Sbjct: 17626 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 17685 Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469 P +S T K P P + V+D E V + + ++ +Y +E R Sbjct: 17686 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 17743 Query: 1470 LGSGKFGQV 1478 +GK+ +V Sbjct: 17744 EVTGKWVRV 17752 Score = 101 bits (252), Expect = 6e-21 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++ Sbjct: 22540 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 22596 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL Sbjct: 22597 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 22656 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 22716 Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432 YG EP + + P+ PK Sbjct: 22717 YGVGEPLESEPVVAKNPFVVPDAPK 22741 Score = 101 bits (251), Expect = 8e-21 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%) Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302 F + VRAG S+ LF G T W K + S + +++ S LT+ + Sbjct: 28363 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 28420 Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362 G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+ Sbjct: 28421 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 28479 Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421 + Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E Sbjct: 28480 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 28539 Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471 E+P P+ D V+ S +P+ D + QK SDF+ +E Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 28598 Query: 1472 SGKFGQVFRLVEK 1484 V RLVEK Sbjct: 28599 KQLTFTVERLVEK 28611 Score = 100 bits (250), Expect = 1e-20 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 ++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L + Sbjct: 21465 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 21524 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG Sbjct: 21525 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 21584 Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 + + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP + Sbjct: 21585 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 21644 Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471 + V P+ PK+ EV D P+ D + IN Y +E R Sbjct: 21645 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 21694 Query: 1472 SGKFGQVFRLVEKKT 1486 K GQ + KKT Sbjct: 21695 -DKAGQRWIKCNKKT 21708 Score = 100 bits (249), Expect = 1e-20 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y Sbjct: 22159 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 22218 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y + Sbjct: 22219 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 22278 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 E D++ TW+ + AT T+ L EY+FR+ A N YG S Sbjct: 22279 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 22324 Score = 100 bits (248), Expect = 2e-20 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%) Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567 V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A Sbjct: 1289 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1348 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623 L I LPED G YT A N G CS + V Y L PV+ + +P Sbjct: 1349 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1408 Query: 624 -------------------------------------------------IFLQGLSDLKV 634 +F+ K Sbjct: 1409 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1468 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 ++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1527 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 +T A N AG +LTV+ +P F+ K ++V G + + G+P P + Sbjct: 1528 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1587 Query: 753 HWLRD 757 WL++ Sbjct: 1588 VWLKN 1592 Score = 100 bits (248), Expect = 2e-20 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A++ S +L +V +PL FI P ++ + E AKFE V P+ Sbjct: 11818 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 11868 Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114 W + Q IT RF L+ G + + + A +E + + E + SG Sbjct: 11869 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 11927 Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144 + VT + F +L + KT F Sbjct: 11928 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 11987 Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190 +++ I E P F KL E C+I+ P Sbjct: 11988 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 12047 Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248 V W K ++PS + ++L + + D+G YTC G+ K S ++ Sbjct: 12048 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 12104 Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287 S++ +++ F ET+ + D+ + I +E K+ S Sbjct: 12105 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 12162 Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341 L NC Q GG AAN + K L KD TA +T Sbjct: 12163 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 12218 Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395 S L+ +++P + + P E + R + G + Sbjct: 12219 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 12268 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 +K + + +F + Q V+E T CEVS +V WF GT + Sbjct: 12269 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 12325 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 + + E+ D L + D TY+C A + + SC+ L V+ Sbjct: 12326 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 12375 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572 F L D V E + +C + ++ W +G I+ + + V L I Sbjct: 12376 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 12434 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632 L +D Y+C A S +TV E+++ +F + L+++ Sbjct: 12435 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 12472 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 +V + + + +VS P EVIW EI E+ + G + L IQ ED G Sbjct: 12473 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 12531 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 Y C +S RT + V E FISKP+++ G+ C+I+ + FP V Sbjct: 12532 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 12582 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796 W RD K L + ++V+ + LV+K G Y +++ Sbjct: 12583 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 12625 Score = 100 bits (248), Expect = 2e-20 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288 MPP I E +V G +V + K+ G T TW K ++ + H+ Sbjct: 16116 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 16174 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348 ++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + + Sbjct: 16175 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 16234 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407 TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A Sbjct: 16235 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 16294 Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 N YG EP + +PE ++ V + D V ++T+N E+ D Sbjct: 16295 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 16343 Score = 99.8 bits (247), Expect = 2e-20 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%) Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343 E + +K PQR S P +P P E+ +++ ++KT+ Sbjct: 739 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 796 Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403 T + V PR SP K P G + ++ +A + Sbjct: 797 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 842 Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463 E S+ K ++ VK ++T R P P+ F + + E +EV Sbjct: 843 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 898 Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523 ++ G + + R+ A+ + VE + P+ S LK+ Sbjct: 899 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 952 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580 VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G Sbjct: 953 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 1012 Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614 +TC A N G VS S ++ V EK+++ +E Sbjct: 1013 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072 Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671 P +P AP F+ K+++G V QV GNP P V W +G + + + Sbjct: 1073 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1132 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 ++ + L I F +D G YT N GE A L + ++ Sbjct: 1133 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1178 Score = 99.4 bits (246), Expect = 3e-20 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++ Sbjct: 23623 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 23679 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351 + L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+ Sbjct: 23680 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 23739 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410 W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y Sbjct: 23740 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 23799 Query: 1411 GTSEPSQES 1419 G EP + + Sbjct: 23800 GVGEPLESA 23808 Score = 97.8 bits (242), Expect = 9e-20 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%) Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +E VK+ C++ + +V W+ + E YED G L + D GT Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 31638 Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522 Y C N G+ S C T++ + + ++E P F+ L + Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 31698 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576 G++ ++ P P +TW +GQ I+ + + G+ +L I + Sbjct: 31699 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 31758 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 D YT +A N G+ SC A +TV L P P+F + L++ + + Sbjct: 31759 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 31808 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695 G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y Sbjct: 31809 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 31868 Query: 696 EAWNSAGEVRTQAVLTVQ 713 A N+AG QA L V+ Sbjct: 31869 TATNTAGSTSCQAHLQVE 31886 Score = 97.4 bits (241), Expect = 1e-19 Identities = 69/251 (27%), Positives = 116/251 (46%), Gaps = 39/251 (15%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G AS+ + S S +R+ + ++P F + P ++ + G +A FE V G Sbjct: 6243 GQYSCSASNPLGTASSS---ARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQP 6299 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 ++TW ++ + I GG + + C + T L I V + D G+YTC+ATN G + +L Sbjct: 6300 MRITWSKDNKEIRPGGNYTITC-VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMGRF 180 +V+ PPKF KL V K+G+ + Sbjct: 6359 SVKE----------------------------------PPKFVKKLEASKVAKQGESIQL 6384 Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 CKI+G P+ +V+W + + L S + ++S N + +L I+ + +D G Y C NG G Sbjct: 6385 ECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG 6444 Query: 241 KASMSAELSIQ 251 AS S L+++ Sbjct: 6445 DASCSTALTVK 6455 Score = 97.4 bits (241), Expect = 1e-19 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y Sbjct: 27575 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 27634 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T++++N + + + + P P G +I++ S+ LSW +GG + YSI Sbjct: 27635 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 27694 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P Sbjct: 27695 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 27742 Score = 97.4 bits (241), Expect = 1e-19 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 32433 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278 + DD G Y + N G+AS A L + G D + R + V E+T Sbjct: 32434 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 32493 Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 +S K +EA++ + S + + S + ++++S ++ + Sbjct: 32494 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 32550 Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396 +K +++ AAR+ +PR+ + GE + PT L V+S Sbjct: 32551 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 32602 Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450 +A ++ + + + S S E V EN K E + I K V Sbjct: 32603 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 32660 Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509 +P R + V +K+ R S S + + + + T +V+ L V Sbjct: 32661 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563 P + LK A + L C V + + +TW +G+ ++ + Sbjct: 32715 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771 Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609 G EL I + D G Y C G Q A+ ++HEK KS +K+ Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831 Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 ++P AP + + GL D V S V+ +G P P IW +G Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 I + + + L I + D+G YTC NSAG V + LT++ D Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 32946 Score = 96.7 bits (239), Expect = 2e-19 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y + Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 19425 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 + +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P Sbjct: 19426 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 19473 Score = 96.7 bits (239), Expect = 2e-19 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%) Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64 K + I+KTS + + R + E AF + I EG + + G + V Sbjct: 33018 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 33068 Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 W NG +T+ + G+ G+ +L I D G TC + G + +LT+ Sbjct: 33069 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126 Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183 SK L D APA ++P + EGQ F+C+ Sbjct: 33127 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 33156 Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243 I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S Sbjct: 33157 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 33216 Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301 +A L + L V + V+ + S SL+ +++S S+ + Sbjct: 33217 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 33259 Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361 + S ++S E K S ++ Q ++ +SSS + Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 33304 Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421 G+ + + E S + KA R IP PK E+ P Sbjct: 33305 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 33336 Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480 + E + + C +G P PEV W G + QE G + L ++ + + Sbjct: 33337 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 33396 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507 D G Y+ + N G S + + + + Sbjct: 33397 DGGLYTLSLGNEFGSDSATVNIHIRSI 33423 Score = 96.3 bits (238), Expect = 3e-19 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%) Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P T PP + + F + +R GE+ L G+ +G +W K + E + + Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346 + + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++ Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405 + +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+ Sbjct: 16928 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987 Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431 A N+YG S+P + V + P++P Sbjct: 16988 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 17018 Score = 95.9 bits (237), Expect = 3e-19 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%) Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +G + + + K P P I D V GE + + T +W K Sbjct: 14366 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 14482 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392 ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+ Sbjct: 14483 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 14541 Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449 DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + + Sbjct: 14542 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 14600 Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474 + + K+ + I E++ G+ Sbjct: 14601 KPPLYDGGSKIMGY--IIEKIAKGE 14623 Score = 95.9 bits (237), Expect = 3e-19 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%) Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561 ++A +E+ P ++ EG C + ++TW + ++ + T Sbjct: 31561 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 31619 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608 E GVA L+++D D GTY C N G+ S A + V KK R+ Sbjct: 31620 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 31679 Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667 ++ + L P + T P++ + G V V ++ +P P V W +G +I+ + Sbjct: 31680 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 31734 Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720 + + FE + L I V +D YT A N GE +A LTV P D T + Sbjct: 31735 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 31794 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F + GQSV ++G P PT+ W +DG+ L + + D + L Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 ++ P G Y + N G SCQ L ++ Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886 Score = 95.5 bits (236), Expect = 4e-19 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%) Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 ++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G Sbjct: 20390 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY Sbjct: 20450 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 20508 Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q + Sbjct: 20509 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 20565 Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 V P P ++ EVS+ V T T++ ++ V D Sbjct: 20566 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 20598 Score = 94.7 bits (234), Expect = 7e-19 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S+ +F + G TW K I +EN+E+ + L I + G + Sbjct: 20788 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 20845 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y + Sbjct: 20846 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 20904 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E Sbjct: 20905 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 20964 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478 P P D + + D + + + + K++ + +R GS ++ + Sbjct: 20965 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 21014 Score = 94.7 bits (234), Expect = 7e-19 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++ Sbjct: 25786 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 25842 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L Sbjct: 25843 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 25902 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 25962 Query: 1410 YGTSEP 1415 YG EP Sbjct: 25963 YGVGEP 25968 Score = 94.4 bits (233), Expect = 1e-18 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 29515 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y + Sbjct: 29516 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 29574 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E Sbjct: 29575 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 29634 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P P ++EV D V TVT+ E+ + D Sbjct: 29635 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 29661 Score = 94.0 bits (232), Expect = 1e-18 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 25465 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y + Sbjct: 25466 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 25524 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E Sbjct: 25525 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 25582 Query: 1428 PEEP 1431 P P Sbjct: 25583 PFSP 25586 Score = 93.2 bits (230), Expect = 2e-18 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%) Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301 +AG + + + G +W K +K +++ H ++E +EN S + I + Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + H G Y++ +NK G + A + V+D P PP SDI S LSW DGG Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 15941 Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 ++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + + Sbjct: 15942 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 16001 Query: 1421 LTTVGEK--PEEPKDEVEV 1437 TT + P +P ++++ Sbjct: 16002 RTTARDPIYPPDPPIKLKI 16020 Score = 92.8 bits (229), Expect = 3e-18 Identities = 60/220 (27%), Positives = 102/220 (46%), Gaps = 36/220 (16%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F L P ++ + G + F+ V G ++TW ++ + I GG + + + T +L Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLT 7270 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 + V + D G+YTC A+N +G + +L V+ Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE--------------------------- 7303 Query: 153 PSIWGECPPKFATKLGRV-VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211 PP+F KL +VK+ + R+ CKI G P+ +V W K +Q S++ +S Sbjct: 7304 -------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 7356 Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 + + VLE+H ++ +D G YTC N +G AS S L ++ Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396 Score = 92.4 bits (228), Expect = 4e-18 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 + P F +L +K A FE R+ G P V W +G+P+ + R + G Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1759 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146 SL + D G TC ATN G + L V E S ++ P K L Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1819 Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199 + ++ G + P V V EG+ RF C++TG PQP+V W Sbjct: 1820 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1879 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 ++ S R V +G+ L+I D G N G +L IQ + RS Sbjct: 1880 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1937 Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318 +R + + E K+D ++K +R + Sbjct: 1938 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1997 Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378 SK + + T V K+ ++ + EE+K A Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2057 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 T PT +P +I + ++ PK + QSQ V + FR V Sbjct: 2058 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2102 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 G P PE W+ G + R + + + L + DS + A N G+ S Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2162 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557 L V+ ++ +F+ L+D E P ++ W +G + Sbjct: 2163 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2218 Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 R + V L I D Y+C V V ++ ++ ++ Sbjct: 2219 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2264 Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672 A + F++ L D++V + + VS PE I W HN E++ + + Sbjct: 2265 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2315 Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694 R + +L +++V ED G Y+ Sbjct: 2316 SRRGRQNLTVKDVTKEDQGEYS 2337 Score = 92.4 bits (228), Expect = 4e-18 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290 P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++ Sbjct: 24705 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 24761 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L + + G Y L + N G++ + + V+D+P PP G + + + L Sbjct: 24762 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 24821 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N Sbjct: 24822 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 24881 Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438 YG EP + +T KP P EVS Sbjct: 24882 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 24911 Score = 92.4 bits (228), Expect = 4e-18 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 T + TV+ T + MP + I P AG VEL + G P +W Sbjct: 29723 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 29776 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 +++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP Sbjct: 29777 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 29836 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394 G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L Sbjct: 29837 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 29896 Query: 1395 LPDHEYKFRVRAINVYG 1411 +EY FRV A N +G Sbjct: 29897 TEGNEYVFRVAATNRFG 29913 Score = 92.0 bits (227), Expect = 5e-18 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 +P+T P + +N+ + EG + E + GYP P VTW+R I S F + Sbjct: 938 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 995 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143 G L+I ED G++TC A N +G + L V+ S + V++ T R Sbjct: 996 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1055 Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194 F S V T S+ E P F TK + EG F C++ G P+P V W Sbjct: 1056 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115 Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 K VPL R VS +++ G L I DD G YT +V N G+ S SA L Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171 Score = 92.0 bits (227), Expect = 5e-18 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AGE V++ G P T TW K K + +EN+++ S LTI + G Y Sbjct: 27284 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 27343 Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I Sbjct: 27344 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 27462 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474 P P ++ + D + + + + ++++ + ER G G+ Sbjct: 27463 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 27506 Score = 91.7 bits (226), Expect = 6e-18 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y + Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 23360 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 + D+ W + AT T+ V L EY+FR+ A N YG S Sbjct: 23361 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406 Score = 91.3 bits (225), Expect = 8e-18 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%) Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301 KV+AGE V + VTG W K I++ +V SE ++L+I A Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 +E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS Sbjct: 15469 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 15527 Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418 + Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ + Sbjct: 15528 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 15587 Query: 1419 SEL 1421 ++ Sbjct: 15588 DKV 15590 Score = 91.3 bits (225), Expect = 8e-18 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%) Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282 P P PP++I +Q ++ G+++ L + G TW K + Sbjct: 17204 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 17263 Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342 + V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+ Sbjct: 17264 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 17320 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401 IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y Sbjct: 17321 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 17380 Query: 1402 FRVRAINVYG 1411 FRV A N YG Sbjct: 17381 FRVAAENQYG 17390 Score = 91.3 bits (225), Expect = 8e-18 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%) Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PKA +PP+I + +KV RA ++ LF + G W R + + Sbjct: 21849 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 21906 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 +E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++ Sbjct: 21907 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 21965 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV Sbjct: 21966 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 22025 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A N YG P++ +E E+P P Sbjct: 22026 LAENEYGIGLPAETAESVKASERPLPP 22052 Score = 90.5 bits (223), Expect = 1e-17 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%) Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 V AG + + V+G P T TW M R QE+ +E + S + I ++ H G Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 16592 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 16651 Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425 IE +S + W + T + VQ L+ Y FR+ A N G + SE + Sbjct: 16652 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 16711 Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475 E PE P+D +EV EV TVT+ D Y +E RL G+ KF Sbjct: 16712 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 16763 Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524 K T + + KE + +S +N + K C Sbjct: 16764 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 16805 Score = 90.1 bits (222), Expect = 2e-17 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ LF + G W K +I+++ + V +S + L + + G Y Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 23011 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y + Sbjct: 23012 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 23070 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E Sbjct: 23071 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 23130 Query: 1428 PEEP 1431 P+ P Sbjct: 23131 PQPP 23134 Score = 90.1 bits (222), Expect = 2e-17 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%) Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278 P P +++++P+ D++ + G V G + T PI C W K + I Sbjct: 30118 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 30177 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G Sbjct: 30178 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 30235 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397 DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L + Sbjct: 30236 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 30295 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454 EY FRV A N +G S+P + E T PE P + EV D + + + Sbjct: 30296 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 30355 Query: 1455 NTEQKVSDFY 1464 + +V+ +Y Sbjct: 30356 DGGSRVTGYY 30365 Score = 89.4 bits (220), Expect = 3e-17 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679 AP F Q L + V++GS T +SG P PEV W +G I S + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122 Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799 + + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 800 VGECSCQVSLMLQ 812 VG + L++Q Sbjct: 182 VGRATSTAELLVQ 194 Score = 89.0 bits (219), Expect = 4e-17 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%) Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467 Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+ Sbjct: 1835 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1892 Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527 G HYL ++ ++ D+G TA N +G + L++++ F SVL+ Sbjct: 1893 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1946 Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V LQ V+ P + L + I + + E+ EL + Sbjct: 1947 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 2004 Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618 + G Y + E L + W E+K + E + + Sbjct: 2005 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2064 Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 KP AP + + V GS V+V G P PE W NG +I+ S+ Sbjct: 2065 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124 Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728 + + L I++V ED+ + +A N AGE + A L VQ T F + + Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2181 Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758 V A ++ +PF V W +DG Sbjct: 2182 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2211 Score = 87.8 bits (216), Expect = 9e-17 Identities = 69/286 (24%), Positives = 118/286 (41%), Gaps = 46/286 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F ++L+ V V + + L+C+V+ PP + W N + ++++K L+ S+ ++ I Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 5014 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA----SENTKAPEMKSRRPKSSL--- 1210 K P D G Y+C+ N+ G CS +V + + P+ ENT S +S++ Sbjct: 5015 TKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGS 5074 Query: 1211 PPVLGT-------------------ESDATVKKKPAPKTPP------------------- 1232 PP+ T +S AT++ + Sbjct: 5075 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF 5134 Query: 1233 -KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P QI++ + V + + L V GT + W+K KQI S + + N Sbjct: 5135 LLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337 + I + ++ G YT VEN GS L V+D+ PP+ T Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 5240 Score = 87.8 bits (216), Expect = 9e-17 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%) Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285 PK + P I + VRAG + LF V G TW K +++ + Sbjct: 18597 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 18653 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+ Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 18712 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV Sbjct: 18713 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 18772 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A+N YG P+ + + EP Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEP 18799 Score = 87.8 bits (216), Expect = 9e-17 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%) Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 P P P I+ PE + +RAG ++ L+ V G P TW K + Sbjct: 19675 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 19734 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 ++ + +++++ + L + G Y L +EN G ++ + + V+D P PP Sbjct: 19735 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 19793 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397 +I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L Sbjct: 19794 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 19853 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428 Y FRV A N YG +P + + + P Sbjct: 19854 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 19884 Score = 87.8 bits (216), Expect = 9e-17 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%) Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I + +KV RA ++ LF + G W K + ++ ++E + + + Sbjct: 25104 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 25161 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW Sbjct: 25162 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 25220 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG Sbjct: 25221 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280 Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P++ +E V E P P V +V T TI E+ SD Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 25322 Score = 87.0 bits (214), Expect = 2e-16 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S + G TW R++ + ++ +++E N ++L+I + G Y Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 24093 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I Sbjct: 24094 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 24152 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 + +S K + +++ C TSF V++L Y FRV A N +G P + + E Sbjct: 24153 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 24212 Query: 1428 PEEP 1431 P P Sbjct: 24213 PSPP 24216 Score = 87.0 bits (214), Expect = 2e-16 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 ++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y + Sbjct: 24383 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 24442 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E D+ TW + AT T+ + L EY+FR+ A N YG S P Sbjct: 24443 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 24490 Score = 86.7 bits (213), Expect = 2e-16 Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 60/269 (22%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F QK V +G ++LQC++S PP ++W + K ++ +K ++ + S+ I Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 6517 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 D G Y C A N+ G CSC V Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSV-------------------------------- 6545 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 K PP+ ++ D G++VEL V G QPI+ W+K R + Sbjct: 6546 ---------------KFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGE 6590 Query: 1278 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDK 1330 I+ESE+ ++ +N + L + + + G Y ++N G R+ LTV ++K Sbjct: 6591 VIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK 6650 Query: 1331 PDP---PAGTPCASD---IRSSSLTLSWY 1353 P+P G P A + + L+ W+ Sbjct: 6651 PEPMTVTTGNPFALECVVTGTPELSAKWF 6679 Score = 85.9 bits (211), Expect = 3e-16 Identities = 73/292 (25%), Positives = 125/292 (42%), Gaps = 41/292 (14%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ VA + S +L V+ E P + + + ++ G A+F + G P+ Sbjct: 3216 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3267 Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P+++W++ Q +++G + FL D ++L++ ED YTCEA N G + Sbjct: 3268 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3324 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 L+VE P V + PP T L V EGQ R Sbjct: 3325 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3363 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F C+++G +V+W + ++PS +++ LEI +D G YT + N Sbjct: 3364 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3422 Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291 G+ S +A LS++ A S + E ++ + VI + K++ LE A Sbjct: 3423 GQVSSTANLSLE----APESILHERIEQEIEMEMKAAPVIKR--KIEPLEVA 3468 Score = 85.5 bits (210), Expect = 5e-16 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472 P F QS V E T F +SG P PEV+WF +G + +++ G L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531 + +SG YS A+N GQ T E L E A P+F L+ V +G Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+ Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616 +G+ + +A + V E+ ++K++ ++ A Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211 Score = 85.5 bits (210), Expect = 5e-16 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+ Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I D G++T A N +G ++V LTVE AVE Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1551 Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210 + P F KL V +KEG + TG P P + WLK + + P ++ + Sbjct: 1552 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1607 Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 G L+I D YT +N +G+ + +++++ Sbjct: 1608 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648 Score = 84.0 bits (206), Expect = 1e-15 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%) Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 + G + +W K + + VE+S + L + ++ G YT+ ++N G+++ Sbjct: 20006 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 +++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W Sbjct: 20066 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 20125 Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 A+ + T+F V L EY FRV A N YG E Sbjct: 20126 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 20160 Score = 83.6 bits (205), Expect = 2e-15 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%) Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I FP VRAG ++++ ++G T + ++ + E + Sbjct: 26473 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 26532 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 + + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W Sbjct: 26533 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 26592 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G Sbjct: 26593 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 26652 Query: 1413 SE 1414 S+ Sbjct: 26653 SD 26654 Score = 83.2 bits (204), Expect = 2e-15 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%) Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 P I++F + +++GES+ + V G TW K +I++ +M++ + + Sbjct: 27955 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 28014 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W Sbjct: 28015 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 28074 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G Sbjct: 28075 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 28134 Query: 1413 SEP 1415 P Sbjct: 28135 GRP 28137 Score = 82.8 bits (203), Expect = 3e-15 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%) Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938 H EE+ QQ + +++ ++S ++E + PA + + + VKP+ + Sbjct: 722 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 772 Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997 SE K + + S + K T V P+ A+P F K +P Sbjct: 773 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 829 Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055 A + K LS + + + + A T+KP AE L A Sbjct: 830 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 886 Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095 + KS + E+KK+V + GTT E+R E Sbjct: 887 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 940 Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155 T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + + Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213 I +A ED G + C A N+AG SC V V + E T E + K + Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +D ++ ++ A P A P I P QK+ G SV +V G W K Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117 Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325 + KV N + G KL I + G YT++V NK G A +L Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171 Score = 82.4 bits (202), Expect = 4e-15 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%) Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457 ++G++ + K + +P Q+V E V+ +VS + E W +G V+ Sbjct: 2340 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2398 Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517 + + + D SH L + D+G YS T L S + +V +V + P Sbjct: 2399 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2450 Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574 LKD VIEG VL+C V V + W LN + I+ ++ + L I Sbjct: 2451 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2508 Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634 D G Y + +G+V + ++V + K ++GL DL Sbjct: 2509 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2544 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694 + V V++S + +V+W EI+ S + E G + L + + +D G YT Sbjct: 2545 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2603 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753 AGE T LTV ISKP T + Q + C +A +P Sbjct: 2604 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2651 Query: 754 WLRDGKAL 761 WLRDGK L Sbjct: 2652 WLRDGKHL 2659 Score = 82.4 bits (202), Expect = 4e-15 Identities = 61/234 (26%), Positives = 96/234 (41%), Gaps = 46/234 (19%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F ++L+ V A KK+ L+CQV D T+ W+ +G+ L K + E + ++ I Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 3703 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 A +D G Y C A N+AG + CS VTV + P Sbjct: 3704 PLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP-------------------------- 3737 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 + VKK + P + P GES L K+ G+ I TW K K+ Sbjct: 3738 --SFVKK-----------VDPSYLMLP-------GESARLHCKLKGSPVIQVTWFKNNKE 3777 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 + ES +++ + + L I + E G Y+ N +GS + + + P Sbjct: 3778 LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831 Score = 82.4 bits (202), Expect = 4e-15 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%) Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144 D E R++ + AP K QD+ V GK L + + P A W + L T Sbjct: 12987 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 13046 Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204 +++ S + +K D+G YK V +N G+AE + V D P Sbjct: 13047 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 13091 Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264 PV E T + + ++ + G S ++ G V Sbjct: 13092 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 13128 Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322 + I TW+ + + E + G + + + G + +N + +R Sbjct: 13129 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 13188 Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W Sbjct: 13189 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 13241 Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 T R+ S V D++ EY FRVRA N G +PS + V + E P V ++ Sbjct: 13242 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 13301 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493 D+ + V + + I ER GK + +LV + T KV K Sbjct: 13302 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 13361 Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516 + SA+ K + I+ L Sbjct: 13362 YLYRVSAENKAGVSDPSEILGPL 13384 Score = 82.4 bits (202), Expect = 4e-15 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG S + G W K ++ + V+ +++ + LTI A + G Y Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 26255 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I Sbjct: 26256 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 26314 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E +++ K W + C S+ V +L Y FRV N +G P++ E + EK Sbjct: 26315 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 26374 Query: 1428 PEEPK 1432 P P+ Sbjct: 26375 PSPPE 26379 Score = 82.4 bits (202), Expect = 4e-15 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G Sbjct: 30907 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 30966 Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 EI + + ++ +G H L I V +D Y A N G V A L V+ P Sbjct: 30967 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 31026 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L Sbjct: 31027 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 31085 Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801 V V+ AG Y + KNR G Sbjct: 31086 VFPNGVERKDAGFYVVCAKNRFG 31108 Score = 82.0 bits (201), Expect = 5e-15 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%) Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78 R D+M L E P F LP N G +F + +PEP VTW+++GQ I G + Sbjct: 31679 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 31738 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + + +G + L I++V +D +YT A N G +LTV L P Sbjct: 31739 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 31791 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 TL P F L +EGQ F +++G P P + W K Sbjct: 31792 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832 Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257 PL + + E L I +D G Y N +G S A L ++ L Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892 Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290 + F + + V+K++ + L E+ Sbjct: 31893 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 31924 Score = 81.6 bits (200), Expect = 7e-15 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306 V+AG+++ L V G W K + + S +K++ + SK ++ A++ G Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272 Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y Sbjct: 18273 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 18331 Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423 +E ++ W AT + V L+ +EY FRVRA N GT P++ + T Sbjct: 18332 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 18391 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464 +KP P D EV+ ++E V + + + ++ ++ Sbjct: 18392 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 18431 Score = 81.6 bits (200), Expect = 7e-15 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 + ED G YTC A N GEV T + L +Q P + K + A +G ++ + Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 30649 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800 G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N Sbjct: 30650 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708 Query: 801 GECSCQVSLMLQN 813 G + + +Q+ Sbjct: 30709 GTVDAILDVEIQD 30721 Score = 81.3 bits (199), Expect = 9e-15 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%) Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L + Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2233 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 L T D+ YSC + + + +L V F L+D V E L+ Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2287 Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 C V + W N ++ T G L ++D ED G Y+ + + Sbjct: 2288 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2342 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 KK++ K + KP LQGLSD KV +G V + V+VS Sbjct: 2343 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2384 Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707 E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V Sbjct: 2385 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2443 Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 +V I+ + V G ++ C ++ +V W + + + K Sbjct: 2444 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2490 Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 + + LV+ + G Y++++ RV E +C +S+ Sbjct: 2491 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2530 Score = 80.9 bits (198), Expect = 1e-14 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 + E ++ F E+S P W L+G + R + E+ + G +L L K + +G Sbjct: 11408 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 11465 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 A NA + L V E+ F+ LKD V E + +C + T Sbjct: 11466 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 11514 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601 + W I+ + + HI D+ +D G YT E + S +VT Sbjct: 11515 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 11572 Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 K F+ L D V +G T ++S + V+W N Sbjct: 11573 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 11611 Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721 ++ S G H L ++EV +D + E+ + A L V E P Sbjct: 11612 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 11663 Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781 +F K TA + + C ++ D V W +DG+ + + + + L + Sbjct: 11664 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 11720 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837 KK G+Y C C N + A L + +P ++ G Sbjct: 11721 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 11771 Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889 + D +G W +GQ D E + K + T + + +A Sbjct: 11772 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 11827 Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949 + L ++L + LS D+K ++ F + R+ PKT R + Q Sbjct: 11828 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 11877 Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007 ++ D R L K GT + V + A F + + +G E + K Sbjct: 11878 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 11931 Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067 + K ++ + + V + +K N + T + + + + + S + ++L Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 11990 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 D + + + G + K + +G P F KLQD E +++LQC++S A Sbjct: 11991 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 12046 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ + Sbjct: 12047 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 12102 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 +D E+K RP S+ V+ TE+ Sbjct: 12103 EDR---------EIKLVRPLHSV-EVMETET 12123 Score = 80.9 bits (198), Expect = 1e-14 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PPKA + ++ + +RAG + L V G W K K++ E + ++ + Sbjct: 29043 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + I + G YTL V+N G++ V + V+D P P G S + TL Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 29159 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N Sbjct: 29160 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 29219 Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433 YG SEP T+ P P++ Sbjct: 29220 YGPGVPVESEPIVARNSFTIPSPPGIPEE 29248 Score = 79.7 bits (195), Expect = 2e-14 Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 47/230 (20%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+F +KL+DV+ G ++L+C+VS P ++ W +G + + S ++C++++ Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 P D G+Y CVA N AG ECS +TV + P+ E T Sbjct: 6801 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT--------------------- 6839 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 P+ +V G S+ + GT P W K ++ Sbjct: 6840 --------------------------PDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE 6873 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 + E + + ++L + + G Y+ LV N GS +L V Sbjct: 6874 LVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 6923 Score = 79.7 bits (195), Expect = 2e-14 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AG+++++ V G T TW K + +++++ + E + + L I + G Y Sbjct: 21078 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 21137 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 L N +G + + V D P PP G ++ S +T SW DGG + +Y +E Sbjct: 21138 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 21197 Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411 + + + TW ELA T T++ L EY+FRV+A N YG Sbjct: 21198 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 21240 Score = 79.3 bits (194), Expect = 3e-14 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Query: 1789 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848 EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD + Sbjct: 1272 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1330 Query: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE Sbjct: 1331 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382 Score = 79.3 bits (194), Expect = 3e-14 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%) Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80 P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R Sbjct: 2066 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125 Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140 LVI V ED +A N +G L V+ AKQL Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2173 Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199 F +L VV KE M F C+ T P +V W K + Sbjct: 2174 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2212 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 + + + + L I ++ D Y+C++V +A+L ++G A Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2268 Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312 FV+E + E+ ++S E+ + +E + K + +RG + Sbjct: 2269 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2328 Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363 + E K +CK + P +LQ S + VQ E + GV Sbjct: 2329 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2387 Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420 G+E +P+ + L +D+ + A IP G S S Sbjct: 2388 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2446 Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 +K+ ++ C+VS V W+L + + + ++ L + Sbjct: 2447 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2505 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 + D G Y G++ + L VE++ ++ L+D E Q+ V + Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2554 Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592 + + + + W + I+ + + + +L + + + +D G YT A G+ Sbjct: 2555 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2609 Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652 S +TV A SKP L+D V + + +V+ NP Sbjct: 2610 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2648 Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + WL +G + + + E G + L I +D G YT + S +T A L V Sbjct: 2649 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2704 Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 + I K +++T + Q + + + V W+++G L Sbjct: 2705 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2747 Score = 79.0 bits (193), Expect = 4e-14 Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 48/265 (18%) Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133 + CK + +D S + P F +KL D+ GK++ LQ + P +++W Sbjct: 7468 EYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK 7527 Query: 1134 N-GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 + G+ ++ + I +S ++ ++ + P + G Y C KNDAG EC ++V + Sbjct: 7528 DKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE--- 7584 Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252 P I++ PE KV G Sbjct: 7585 --------------------------------------------PATIVEKPESIKVTTG 7600 Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312 ++ L V GT ++ W K K++ K+ S L I+ G Y+ V Sbjct: 7601 DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEV 7660 Query: 1313 ENKLGSRQAQVNLTVVDKPDPPAGT 1337 +N +G +L V D+ PP+ T Sbjct: 7661 QNPVGKDSCTASLQVSDRTVPPSFT 7685 Score = 79.0 bits (193), Expect = 4e-14 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471 P+F ++ + V+F ++ P+P V W+ G ++ + + D G + Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528 L + T D Y+ A N G+ SC L V + P F +L + EG Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 31809 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584 Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y Sbjct: 31810 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 31869 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611 A N G SC A + V E+ +K E+ Sbjct: 31870 ATNTAGSTSCQAHLQV-ERLRYKKQEF 31895 Score = 78.6 bits (192), Expect = 6e-14 Identities = 67/283 (23%), Positives = 111/283 (39%), Gaps = 60/283 (21%) Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151 + Q P+F ++L+DV G ++ C +S P ++ W +GK LK + + S + Sbjct: 8051 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 8110 Query: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP 1211 +++I K G Y C A N G A S ++ + +E P R L Sbjct: 8111 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL-----TEGKNPPFFDIR-----LA 8160 Query: 1212 PVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271 PV DA V GES + VTGTQPI +W Sbjct: 8161 PV-----DAVV-----------------------------GESADFECHVTGTQPIKVSW 8186 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 K ++I+ ++ EN + LT+L + G YT N++G L + ++ Sbjct: 8187 AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERL 8246 Query: 1332 DPPAGTPCASD----------------IRSSSLTLSWYGSSYD 1358 PP+ T S+ S +T++WY ++ + Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 8289 Score = 78.6 bits (192), Expect = 6e-14 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%) Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276 +P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K Sbjct: 14664 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 14721 Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310 ++QE E + ++NS+ G S+L + + + G Y + Sbjct: 14722 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 14781 Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370 VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E Sbjct: 14782 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 14840 Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 D + W + +T R ++V L+ EY FRVRA N +G P L V + Sbjct: 14841 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 14898 Query: 1428 PEEPKD 1433 P P D Sbjct: 14899 PFGPPD 14904 Score = 78.2 bits (191), Expect = 7e-14 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%) Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94 I P +++ + EG A E +V V W+ N + I R + ++GT LVI+ Sbjct: 2448 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2505 Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154 H D G Y G + L+VE Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2533 Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214 K L + E Q F +++ V W + ++PS++ + Sbjct: 2534 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2585 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272 + L + + +DD G YT +G+ S +L++ G + ++ +T A + + Sbjct: 2586 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2640 Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329 EV N SK L + + N S G A K+ + K S Sbjct: 2641 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2700 Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378 + + ++KT ++T+ + P G+ GV+ S E+ Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2760 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 + + + + V R + + K KP+ EN TV F VS Sbjct: 2761 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2819 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P V WF + ++ + + + H L L D+G Y+ GQL C Sbjct: 2820 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2873 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 L VE L + + +K+ V E + +C V VP + WL NG I+ + Sbjct: 2874 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2925 Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 + + +L I + ED YT + N QVS + VT Sbjct: 2926 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2967 Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674 PI + L D+ + +T V V+ WL NG EI+ ++ + Sbjct: 2968 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 3019 Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 HSL I+ V D YT AG+ + A L V+ H F + + Sbjct: 3020 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3071 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 + + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y + Sbjct: 3072 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129 Query: 795 LLKNRV 800 + V Sbjct: 3130 VAGGNV 3135 Score = 78.2 bits (191), Expect = 7e-14 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%) Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 P T A + P + F + +V + + TG T TW K ++ + +K Sbjct: 13383 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 13442 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 ++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI Sbjct: 13443 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 13501 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404 S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V Sbjct: 13502 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 13561 Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433 A N G EP+ E ++T P+ P++ Sbjct: 13562 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 13593 Score = 78.2 bits (191), Expect = 7e-14 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA ++L V ++ +L + D + I L K + F + + + ++ Sbjct: 28546 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 28605 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 E+ + + ++ AKNDAG +E P+ + V+ Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 28637 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +K+ T + Q+I +AG + ++G TW + Sbjct: 28638 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 28687 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337 ++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G Sbjct: 28688 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 28747 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396 S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L Sbjct: 28748 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 EY FRV + N +G S+P + + + + E P P Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 28840 Score = 77.4 bits (189), Expect = 1e-13 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%) Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118 Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509 G P+ + + G L + D+G Y+ N G+ S S +L +E Sbjct: 1119 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567 + S +L V FV + V G P + + + ++ +A+ Sbjct: 1178 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625 + ++ + + + E + ++ T E+ + + + + ++ S+ F Sbjct: 1234 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1293 Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683 + + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I Sbjct: 1294 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1352 Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732 V PED G YT A N G L V+ P +I PRSV+ Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412 Query: 733 S 733 S Sbjct: 1413 S 1413 Score = 77.4 bits (189), Expect = 1e-13 Identities = 62/218 (28%), Positives = 93/218 (42%), Gaps = 32/218 (14%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 E P FI P ++ G A + +V G PE +++W++ + S + + S Sbjct: 7018 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFK-NNVAS 7076 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 LVI+ V D G+Y+C+A N GA + L ++ A++L Sbjct: 7077 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK---ARKL------------------- 7114 Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210 PP FA KL V G F C+I G QV+W K V L+ A + S Sbjct: 7115 ---------PPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTS 7165 Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 + + L+I +Q +G Y C N G AS SA+L Sbjct: 7166 FVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203 Score = 77.0 bits (188), Expect = 2e-13 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI Sbjct: 23230 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 23289 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y N GQ S ++ D P + K P Sbjct: 23290 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 23332 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 D + + PP QI + ++ T W Sbjct: 23333 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 23376 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332 + + +KV + G++ + + EN+ G A + +V +P Sbjct: 23377 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 23424 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385 PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT Sbjct: 23425 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 23478 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 T F Q+L EY+FRV A N+ G + S+ SE + + P Sbjct: 23479 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 23524 Score = 76.6 bits (187), Expect = 2e-13 Identities = 66/242 (27%), Positives = 101/242 (41%), Gaps = 22/242 (9%) Query: 13 SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68 + SLSV+ V S MP+ PA I P ++ EG A+F+ RV G + +V+W+ Sbjct: 3322 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3379 Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128 + I RF T+ L I + ED G YT A+N G T L++E Sbjct: 3380 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP-- 3436 Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 L +R +E + + P K+ + V G + +F+C+I P Sbjct: 3437 --------ESILHER-----IEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 3483 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 + W K + S + S+ + LEI D G YTC N G S +A L Sbjct: 3484 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543 Query: 249 SI 250 ++ Sbjct: 3544 TV 3545 Score = 76.6 bits (187), Expect = 2e-13 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+ Sbjct: 12825 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 12883 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206 +D Y C ++ +A + + V+ +AP ++ E+ + Sbjct: 12884 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 12943 Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241 ++++ V G + + K + + A P+I Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 13003 Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301 +D V G+ + + W K + + ++ + + IL A+ Sbjct: 13004 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 13060 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS Sbjct: 13061 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 13119 Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418 + Y +E D KTW LAT R+ S F V L EY FRV A N GT EP + Sbjct: 13120 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 13178 Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441 K + P + V+ D Sbjct: 13179 DNPVEARSKYDVPGPPLNVTITD 13201 Score = 76.3 bits (186), Expect = 3e-13 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%) Query: 1772 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1830 S TG+ E L E V++ E P P ++++ V+EG + +C Sbjct: 905 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964 Query: 1831 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G Sbjct: 965 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023 Query: 1891 ATCTAELIVETMEEGEGE 1908 + + L V+ EE E E Sbjct: 1024 VSTSCYLAVQVSEEFEKE 1041 Score = 76.3 bits (186), Expect = 3e-13 Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 48/234 (20%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+F + L+ + G LLQC+VS P I W + K ++++K L + SL + I Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 3890 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 D G Y+CV N+ G +C C T Sbjct: 3891 FSFNSADVGEYECVVANEVG--KCGCMAT------------------------------- 3917 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +K+ PP ++ +D G++V L V G++PI+ TWMK ++ Sbjct: 3918 --HLLKE------------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 3963 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 I+E +K+ S + L I + G YT L EN+ GS Q V +V +P Sbjct: 3964 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS-QTSVGELIVKEP 4016 Score = 75.9 bits (185), Expect = 4e-13 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%) Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105 N++P ++LK +E + D + + + +A G ++ + SE+ P + Sbjct: 14335 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 14394 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165 D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D Sbjct: 14395 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 14454 Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225 G+Y +N G A S V V P ++K+ SD T Sbjct: 14455 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 14496 Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PP+ G PI ++ R++ ++ Sbjct: 14497 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 14528 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343 V + EN T+ + + NK+G + N + P P P ++ Sbjct: 14529 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 14588 Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395 + ++T++W YDGGS + Y IE + WK C ++ + L Sbjct: 14589 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 14645 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442 EY+FRVRA N G SEPS+ + T + + PK +EV DE Sbjct: 14646 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 14696 Score = 74.7 bits (182), Expect = 8e-13 Identities = 69/308 (22%), Positives = 120/308 (38%), Gaps = 73/308 (23%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F V + ++ L+C++S PP ++W + + L+++K ++ + S+ I Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 5576 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 D G Y C A+N+ G C C Sbjct: 5577 LNVDTSDIGEYHCKAQNEVGSDTCVC---------------------------------- 5602 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 TVK K PP+ + V AGE EL + G QPI W+K +++ Sbjct: 5603 ---TVKLKE----------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649 Query: 1278 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVDK 1330 I+ESE++++ EN + L A + G Y ++N G R+ L +V+K Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEK 5709 Query: 1331 PDP---PAGTPCASDIR---SSSLTLSWYG-------------SSYDGGSAVQSYSIEIW 1371 P G C + + + L++ WY S Y+ S+++ S+E Sbjct: 5710 AGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQ 5769 Query: 1372 DSANKTWK 1379 D+ T++ Sbjct: 5770 DAGTYTFQ 5777 Score = 74.3 bits (181), Expect = 1e-12 Identities = 59/236 (25%), Positives = 93/236 (39%), Gaps = 29/236 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA LQD +EG+ QC+VS + W K +K ++F ++Q + I Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 +A PED G Y VA N GQ + ++++ P+S L + E Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLE----------------APESILHERIEQE 3447 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 + +K P K E +V G + ++ + W K ++ Sbjct: 3448 IEMEMKAAPVIKRKI------------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 3495 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 I ES+ + +S+ S L IL + CG YT N+ GS LTV + P Sbjct: 3496 IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551 Score = 73.9 bits (180), Expect = 1e-12 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VKE Q V F CEV+ + WF + I + +D + L + A D Sbjct: 12651 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 12708 Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 Y+ + +N +G+ + + L VE + V P LKD +E + C V V Sbjct: 12709 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 12763 Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W NG+ + + H I+D D G Y VT Sbjct: 12764 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 12807 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 + KS +E L+ AP++ F++ L D V + + Q+S V W NG Sbjct: 12808 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 12859 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719 EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P + Sbjct: 12860 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 12915 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 +P P+ + + G V+ + D V WLR+ + + H +++ + L Sbjct: 12916 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 12968 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808 + ++P G+Y + K++ +++ Sbjct: 12969 QICDIKPRDQGEYRFIAKDKEARAKLELA 12997 Score = 73.9 bits (180), Expect = 1e-12 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V+V G L + +S P + + +G LK T ++++++++ D G Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224 Y+ A N +G + + V D P P V+ TE T+K Sbjct: 26546 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 26591 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P PK + + I+ ++ S ++ +V+ T + T MK K E+ Sbjct: 26592 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 26641 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344 +EN + + + S V L P PP+ TP +++ Sbjct: 26642 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 26682 Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402 S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F Sbjct: 26683 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 26742 Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 RV A N G +PS SE + E P++ V ++D + + ++ + K++ Sbjct: 26743 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 26801 Query: 1463 FYDIEER 1469 Y +E R Sbjct: 26802 -YIVERR 26807 Score = 73.2 bits (178), Expect = 2e-12 Identities = 87/395 (22%), Positives = 147/395 (37%), Gaps = 84/395 (21%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+F +KL+ + +G + L+C V+ P +I W + + + ++ S + + I Sbjct: 4675 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 4734 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + D G Y C A N AG +CS +TV + Sbjct: 4735 SQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------------------- 4766 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 PP ++ P+ Q V V+L V GT P+T W K K+ Sbjct: 4767 -------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE 4807 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDKP 1331 + V + + L + AA+ G Y + N +G+ ++ L V + KP Sbjct: 4808 LHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 4867 Query: 1332 DP------PAGTPCASDIRSS-SLTLSWYGSSYDGG--SAVQSYSIEIWDSANKTWKELA 1382 P T I + + +SWY DG +A+Q + I D LA Sbjct: 4868 SPVLVLRNGQSTTFECQITGTPKIRVSWY---LDGNEITAIQKHGISFIDG-------LA 4917 Query: 1383 TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL----TTVGE-KPEE--PKDEV 1435 T F + ++ + A N GT+ S E ++ T + E KP E +V Sbjct: 4918 T-----FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDV 4972 Query: 1436 EVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL 1470 E+ + P + + N E + S Y + +R+ Sbjct: 4973 ELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV 5007 Score = 73.2 bits (178), Expect = 2e-12 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328 R+++ ++ +++ G+ L + ++ + + EN+ G S + T + Sbjct: 30267 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 30326 Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386 + P+PP+ P D+ SS++LSW DGGS V Y IE +++ W + Sbjct: 30327 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 30386 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437 T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+ Sbjct: 30387 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 30439 Score = 72.4 bits (176), Expect = 4e-12 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%) Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++ Sbjct: 15098 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 15153 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347 N S+L I A ++ G Y + N GS+ A + V D P P R Sbjct: 15154 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213 Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407 L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A Sbjct: 15214 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 15272 Query: 1408 NVYGTSEPSQESELTTV 1424 N +G P + + V Sbjct: 15273 NKFGCGPPVEIGPILAV 15289 Score = 72.0 bits (175), Expect = 5e-12 Identities = 59/235 (25%), Positives = 95/235 (40%), Gaps = 48/235 (20%) Query: 1098 PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 P F +KL+ VA +G+ + L+C++S P + W N L + +S S+ ++ Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 6423 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 I +A ED G Y C A N G A CS +TV KAP + +++P Sbjct: 6424 INEASAEDSGDYICEAHNGVGDASCSTALTV---------KAPPVFTQKPS--------- 6465 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 P A+ G V L +++GT P W+K RK Sbjct: 6466 ---------------PVGAL--------------KGSDVILQCEISGTPPFEVVWVKDRK 6496 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 Q++ S+ K+ + + L IL G Y N++GS ++ + P Sbjct: 6497 QVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 6551 Score = 72.0 bits (175), Expect = 5e-12 Identities = 103/475 (21%), Positives = 169/475 (35%), Gaps = 98/475 (20%) Query: 993 AENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKP--MGNAKPAETL--K 1048 A NG A A V++ P+ +PS PVG K ++ + + P E + K Sbjct: 6439 AHNGVGDASCSTALTVKAP-PVFTQKPS----PVGALKGSDVILQCEISGTPPFEVVWVK 6493 Query: 1049 PMGNAKPDENLKSASKE--------ELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAF 1100 + + K SK L+ + +CK + +D S P F Sbjct: 6494 DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRF 6553 Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIEK 1159 +KL D G + L+ V P +++W + G+ ++ ++ +S ++ ++ + Sbjct: 6554 VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGS 6613 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219 + G Y C KNDAG ECS +TV + Sbjct: 6614 PEASNSGKYICQIKNDAGMRECSAVLTVLE------------------------------ 6643 Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279 P +II+ PE V G L VTGT ++ W K +++ Sbjct: 6644 -----------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELS 6686 Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339 + + L I A G Y+ V+N +G V++ V D+ PP+ Sbjct: 6687 ADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRK 6746 Query: 1340 ASDIR---------------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 D+ S+ +++ W+ DG V + S N C Sbjct: 6747 LKDVNAILGASVVLECRVSGSAPISVGWF---QDGNEIVSGPKCQSSFSEN-------VC 6796 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKP--EEPKDEVEV 1437 + N+ L P + A NV G+ E S + TV E P E+ D VEV Sbjct: 6797 ---TLNLSLLEPSDTGIYTCVAANVAGSDEC---SAVLTVQEPPSFEQTPDSVEV 6845 Score = 71.6 bits (174), Expect = 7e-12 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 +D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T Sbjct: 27164 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 27222 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+ Sbjct: 27223 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 27276 Score = 71.2 bits (173), Expect = 9e-12 Identities = 63/276 (22%), Positives = 108/276 (39%), Gaps = 48/276 (17%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGY 59 G AS+ K S S + + E P FI L P + +K+ ++E ++ G Sbjct: 7280 GQYTCYASNIAGKDSCSAQ------LGVQEPPRFIKKLEPSRI-VKQDEFTRYECKIGGS 7332 Query: 60 PEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 PE +V W+++ I +F + + L +H + ED G YTCEA N +G+ + Sbjct: 7333 PEIKVLWYKDETEIQESSKFRMSF-VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 L V+ PP F K + +G Sbjct: 7392 SLKVKE----------------------------------PPIFRKKPHPIETLKGADVH 7417 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 C++ G P V+W K L+ + + +N + + I V+ D+G Y C N Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477 Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275 G + ++++ A FV++ ++ V KEV Sbjct: 7478 GSDTCVGSIALK----APPRFVKKLSDISTVVGKEV 7509 Score = 71.2 bits (173), Expect = 9e-12 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%) Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324 P T W++ K + +V+ N K + +L EN G + + Sbjct: 13924 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 13972 Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 + + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W Sbjct: 13973 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 14032 Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437 +A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV Sbjct: 14033 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 14092 Score = 70.9 bits (172), Expect = 1e-11 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P Sbjct: 1526 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1584 Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P + W +N I + ++ G +G +L I + +D YT A N +G Sbjct: 1585 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643 Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161 ++ VE FA+ + + G +AP +E +G + P Sbjct: 1644 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1703 Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 F KL + +K F C++T G P V WL PL+ + R+ + + G L+ Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1763 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 D G+ TC N G SA L ++ +S V E++ Sbjct: 1764 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1805 Score = 70.9 bits (172), Expect = 1e-11 Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 46/249 (18%) Query: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 P+F ++L + V EG L+ +V+ P T+ W N ++ T ++ + + + Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQ 8308 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 + KA D GLY C NDAG A C+ + + Sbjct: 8309 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVI----------------------------- 8339 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 K P K PP Q V GE V+L V G++PI W+K + Sbjct: 8340 ------------KEPKK---PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 8384 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD-PPA 1335 +I+ S+ + + L + + G Y N GS + +T+ DKP PA Sbjct: 8385 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPA 8444 Query: 1336 GTPCASDIR 1344 A D R Sbjct: 8445 TKKAAVDGR 8453 Score = 70.9 bits (172), Expect = 1e-11 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 27632 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y + N C++ V P + T P K + P Sbjct: 27633 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 27663 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283 I+F E + +SV L V G ITC ++ R+ Q + Sbjct: 27664 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 27705 Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337 M + + K+ L E+ + + EN+ G Q V+ +V K P PP G Sbjct: 27706 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 27762 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395 P ++ S ++L+W YDGGS V + +E + + W+++ T + L+ Sbjct: 27763 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 27822 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455 +Y+FRV A N G S PS S+ T+ P +P + D V T+T+ Sbjct: 27823 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 27874 Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475 + D Y IE+R G+ ++ Sbjct: 27875 WNPPLRDGGSKIVGYSIEKRQGNERW 27900 Score = 70.5 bits (171), Expect = 2e-11 Identities = 51/205 (24%), Positives = 79/205 (38%), Gaps = 32/205 (15%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106 G FE R+ G QV+W+++G + L + +L I + G+Y C Sbjct: 7130 GFPVAFECRINGSEPLQVSWYKDGVLLKDDAN-LQTSFVHNVATLQILQTDQSHIGQYNC 7188 Query: 107 EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166 A+N G + +L + E PP F K Sbjct: 7189 SASNPLGTASSSAKLILSEH-------------------------------EVPPFFDLK 7217 Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226 V + G+ G F C +TG ++TW K N ++P ++ L + V + Sbjct: 7218 PVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKG 7277 Query: 227 DVGVYTCLVVNGSGKASMSAELSIQ 251 D G YTC N +GK S SA+L +Q Sbjct: 7278 DAGQYTCYASNIAGKDSCSAQLGVQ 7302 Score = 70.5 bits (171), Expect = 2e-11 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A + I+ L+V +D F +P +++ + E A+FE + E Sbjct: 11464 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 11512 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W + I S +F + + LVI+ +D G YT E Sbjct: 11513 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 11557 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 VEG K R + KF + L VKEG+ F Sbjct: 11558 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 11594 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C+++ + V W K + L S V +S + LE+ V DD+ V + Sbjct: 11595 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 11649 Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283 S +A+L + D + + A D V K+V K+ Sbjct: 11650 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 11709 Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337 K D L K K +G G+ AN + R K+E P + V Sbjct: 11710 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 11764 Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397 + I L V + + G + + E Q G+ + +V + Sbjct: 11765 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 11823 Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456 AAN + + P P S +V E KF CEVS PK W L+GT Sbjct: 11824 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 11880 Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516 + E+ +D H + + A D Y A + +L + + F Sbjct: 11881 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 11931 Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576 + LKD E + V + + R+ W N Q + RS + +QD Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 11982 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 T+ L+ + Q+ A SE L V P F L D ++ Sbjct: 11983 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 12031 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 +V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+ Sbjct: 12032 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 12090 Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 G +T L +++ + + SV ++ I+ D +W Sbjct: 12091 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 12141 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781 G+AL + T E+ + + +LVL Sbjct: 12142 KGEALLQ-TPDCEIKEEGKIHSLVL 12165 Score = 70.5 bits (171), Expect = 2e-11 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L + V G K+ L V+ P I WT LK K I + +V+I + Sbjct: 13697 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 13756 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y A N G+A +V V D P PP +D T + Sbjct: 13757 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 13798 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 PP+ +I + +++ E W K ++++ Sbjct: 13799 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 13842 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339 K T L +E+ + + EN G Q + +T + DPP G P Sbjct: 13843 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 13889 Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396 SDI ++TL+W DGGS + Y +E D W + T++ V+ L Sbjct: 13890 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 13949 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 +Y+FRV A N+ G +PS+ +E + + + P Sbjct: 13950 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 13984 Score = 70.1 bits (170), Expect = 2e-11 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1866 P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L I V + +Y+ KA N G+AT TAEL+V+ Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98 Score = 69.7 bits (169), Expect = 3e-11 Identities = 51/223 (22%), Positives = 89/223 (39%), Gaps = 38/223 (17%) Query: 26 SMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83 ++ + E P+F+ + P L + G +A+ +++G P QVTW +N + ++ + Sbjct: 3730 TVTVREPPSFVKKVDPSYLMLP-GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF 3788 Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 + L I V ED G Y+CEA N G+ + E+ ++ Sbjct: 3789 -VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------------------ 3829 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 PP F L + G C+++G +++W K ++ Sbjct: 3830 ----------------PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS 3873 Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246 S + + + + LEI N DVG Y C+V N GK A Sbjct: 3874 SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA 3916 Score = 69.3 bits (168), Expect = 3e-11 Identities = 61/269 (22%), Positives = 98/269 (36%), Gaps = 61/269 (22%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+F+Q V V G L + PP + W + L + +S E + + + Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELEL 6893 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + P + G Y C+ NDAG A C+ + V + Sbjct: 6894 FEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP--------------------------- 6926 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 AT K+ A D V G + L TGT PI+ +W+K Sbjct: 6927 --ATFVKRLA------------------DFSVETGSPIVLEATYTGTPPISVSWIKDEYL 6966 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------ 1331 I +SE + +E + L IL + E Y+ L+EN+ G + ++V++ P Sbjct: 6967 ISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPL 7026 Query: 1332 -------DPPAGTPCASDIRSSSLTLSWY 1353 PA C D + + +SWY Sbjct: 7027 EHVEAVIGEPATLQCKVD-GTPEIRISWY 7054 Score = 69.3 bits (168), Expect = 3e-11 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%) Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271 ESD V + P P TP A+ + + V G S + + + + W Sbjct: 23410 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 23469 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 K K I K +N E G + + + EN +G +A N Sbjct: 23470 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 23518 Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387 DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T Sbjct: 23519 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 23578 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438 F V L D Y+FRV A N G S+PS + T ++ E P +D + V+ Sbjct: 23579 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 23638 Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495 + E D + T + + +IEE F+ L+ K ++ G++ Sbjct: 23639 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 23698 Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554 +A + ++ + +++ P+ VQ EK ++ + GG + E Sbjct: 23699 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 23758 Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598 E + E + +++ EG EY+ + IM VNK G Sbjct: 23759 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 23800 Score = 69.3 bits (168), Expect = 3e-11 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357 GC Y + EN G ++ DP P P D +++T++W + Sbjct: 26050 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 26109 Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS Sbjct: 26110 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 26169 Query: 1417 QESELTTVGEKPEEPKDEVE 1436 S+ E+ EEP +++ Sbjct: 26170 DSSDPQIAKEREEEPLFDID 26189 Score = 69.3 bits (168), Expect = 3e-11 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%) Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310 E S ++EVT + E + + + A + + S+ + R SP + Sbjct: 32229 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 32288 Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368 S+PQP E + ++ + SP TP + PR+P SP Sbjct: 32289 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 32323 Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423 ER R A F +R + + K + R+ + Q+ P+ + +S Sbjct: 32324 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 32383 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 V Q +F V P EV W+ G ++ + I +G L +L T DSG Sbjct: 32384 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 32442 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542 TY +N +G+ S TL V G D+ S R V Sbjct: 32443 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 32480 Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596 PR + + YA S+ EA + ++ + E + + +A ++ +A Sbjct: 32481 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 32540 Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654 ++ EK ++RK + L A L + V +G + G P P V Sbjct: 32541 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592 Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714 WL G + S + + I V D G Y+ NS G+ + LT+Q+ Sbjct: 32593 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 32652 Score = 69.3 bits (168), Expect = 3e-11 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L AP L R+ + G +F V+ P +V W+ NG + + G Sbjct: 32370 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 32428 Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121 +L I H +D G Y T + T G R V EL Sbjct: 32429 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 32488 Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157 T ++A K+ + S ++ + + ETR S+ Sbjct: 32489 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 32547 Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 + TK + V EG+ RFSC G P P VTWL+ L SAR Sbjct: 32548 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 32607 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267 V+ EI V D G Y+ +V N GK L+IQ ++ V E KA Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 32660 Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327 S R V S E ++ S EA K SP+ P P + + E + Sbjct: 32661 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 32711 Query: 328 SPRTAP 333 P +AP Sbjct: 32712 LPVSAP 32717 Score = 68.9 bits (167), Expect = 4e-11 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%) Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 P KL V V G + L+ V P + WT + T+ + + Sbjct: 18201 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 18260 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213 S+ KA D G Y A N AG V V D P N K ++ S R Sbjct: 18261 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 18312 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 TV P P+ + I++ E +++ W Sbjct: 18313 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 18345 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330 + + G+ +T L E+ + + ENK+G+ + V+ K Sbjct: 18346 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 18393 Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 PDPP T + + +T+ W YDGG ++ Y +E + + W + + Sbjct: 18394 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 18449 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 VQ+LLPDHEY+FRV+A N G EPS S V + P EP Sbjct: 18450 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 18496 Score = 68.6 bits (166), Expect = 6e-11 Identities = 57/219 (26%), Positives = 88/219 (40%), Gaps = 35/219 (15%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P+FI +++ GA+ E RV G V W ++G I SG + +L Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFS-ENVCTLN 6799 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 + + D G YTC A N +G+ + + LTV+ Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE--------------------------- 6832 Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212 PP F V V G F+ I G P +V W KG+ L P ++S + Sbjct: 6833 -------PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLE 6885 Query: 213 NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 + + LE+ V + G Y+CLV N +G AS + L ++ Sbjct: 6886 DFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924 Score = 68.6 bits (166), Expect = 6e-11 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 25454 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++A ED G Y+ N AG + V D P PP Sbjct: 25455 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 25496 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 + + PP+ QI + ++K + + TW + Sbjct: 25497 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 25540 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333 + + +K+ GS+ + + EN+ G + VV + P Sbjct: 25541 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 25588 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386 P GTP S++ ++W DGGS V Y +E +W ANK Sbjct: 25589 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 25643 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446 T V L Y++RV A N+ G + S+ E P +P + EV++ K Sbjct: 25644 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 25702 Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475 + + + K++ + L G++ Sbjct: 25703 LKWSKPHYDGGAKITGYIVERRELPDGRW 25731 Score = 68.6 bits (166), Expect = 6e-11 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+ Sbjct: 33127 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 33186 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194 ++ S+ I A D G Y AKN GQ + + V + P+ E Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 33246 Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235 ++++ +M + + ++S + + + + K A + + Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 33306 Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 +PP+I P D + G+ + + TG TW Sbjct: 33307 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 33366 Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ + Sbjct: 33367 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420 Score = 68.2 bits (165), Expect = 7e-11 Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 45/235 (19%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 AP K+K++ + VA G C++ S P W G+ + + + + S+ Sbjct: 3455 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 3514 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 I + D G Y C A N+ G C+ +TV +A Sbjct: 3515 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA-------------------------- 3548 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 PP + P+ G++ + VTGT I W K Sbjct: 3549 -------------------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 3589 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 + S + ++ ++EN L + + G Y+ NK G+ Q L ++DKP Sbjct: 3590 ALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644 Score = 68.2 bits (165), Expect = 7e-11 Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 12/162 (7%) Query: 1744 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1798 KW K G + A I +++A + S +G T ++ E S + + L+ Sbjct: 4049 KWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 4108 Query: 1799 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1858 + P+F+K +R+++ V R DCKI G V WFKD + I S ++I Sbjct: 4109 R------DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIA 4162 Query: 1859 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + E G SL I V +D +TC+A NS+G + LIV+ Sbjct: 4163 FVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203 Score = 68.2 bits (165), Expect = 7e-11 Identities = 60/273 (21%), Positives = 101/273 (36%), Gaps = 63/273 (23%) Query: 1097 APA-FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155 APA F ++L D + +GK L+L+ + PP ++ W NG + ++ ++ + Sbjct: 7866 APAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAIL 7925 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215 I + ED G Y C +N +G+ CS Q+ + + Sbjct: 7926 EIPSSTVEDAGQYNCYIENASGKDSCSAQILILE-------------------------- 7959 Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 PP ++ E KV G+S L ++ GT I +W K Sbjct: 7960 ---------------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGD 7998 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 +++ + K+ N + L G Y EN +G A LTV ++ PP+ Sbjct: 7999 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPS 8058 Query: 1336 ------------GTPCASDIR---SSSLTLSWY 1353 G P D S +++SWY Sbjct: 8059 FSRQLRDVQETVGLPVVFDCAISGSEPISVSWY 8091 Score = 67.4 bits (163), Expect = 1e-10 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%) Query: 1788 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198 Score = 67.4 bits (163), Expect = 1e-10 Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154 P Q+LQ V V GK +S P I W + L T KF+ QE +L Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + +A PED +Y C AKND G A S ++V+ PE+ S P +P Sbjct: 3299 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3341 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP II +D G+ +V+GT + +W Sbjct: 3342 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3380 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 K+I+ S ++ E+ +L I A E G YT + N +G + NL++ Sbjct: 3381 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433 Score = 67.0 bits (162), Expect = 2e-10 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 ++ + V G + + P T WT +G +KT + + + ++I+ L Sbjct: 17517 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 17576 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y+ N AG + +TV D P P + + T T+ Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 17624 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P P I E Q R + +G V+ Sbjct: 17625 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 17655 Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336 +GS T L GC + + ENK+G + V K P P G Sbjct: 17656 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 17708 Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390 P +DI ++ T+SW DGGS + Y +E W NKT F Sbjct: 17709 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 17763 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 V L + Y+FRV A N+ G S+PS S+ Sbjct: 17764 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 17793 Score = 67.0 bits (162), Expect = 2e-10 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224 A+N +G + ++ V D P + K +M S R S P L G+E + Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 19426 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 K P A +V+ T PIT ++ K I+ E+ Sbjct: 19427 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 19459 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340 + + ENK G + K DPP P Sbjct: 19460 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 19496 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 S+I +T+SW + DGGS + Y +E ++ W ++ + L Sbjct: 19497 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 19556 Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420 EY+FRV AIN G +PS S+ Sbjct: 19557 EYEFRVTAINKAGPGKPSDASK 19578 Score = 66.6 bits (161), Expect = 2e-10 Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 48/235 (20%) Query: 1098 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 P F +K V V G+ +CQ++ P + W L+G + + +S L + Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 4920 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 I A E+ G Y C A+NDAG A CS ++ V + P T E+K Sbjct: 4921 ISGARVENSGTYVCEARNDAGTASCSIELKVKEPP----TFIRELK-------------- 4962 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 P +++++ + VEL +VTGT P TW+K + Sbjct: 4963 --------------------PVEVVKYSD---------VELECEVTGTPPFEVTWLKNNR 4993 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +I+ S+ + + + L I G Y +V N+ GS + + + P Sbjct: 4994 EIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP 5048 Score = 66.6 bits (161), Expect = 2e-10 Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 47/261 (18%) Query: 1074 DVNCKRGHAGTTDNEK---RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII 1130 + CK ++ T + K R + + P+F ++L+D+ G + L C+++ P + Sbjct: 6148 EYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVC 6207 Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190 W +G L+ + + S ++ ++ I + G Y C A N G A S ++T Sbjct: 6208 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT---- 6263 Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250 +R PK S P P V Sbjct: 6264 ------------AREPKKS----------------------------PFFDIKPVSIDVI 6283 Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310 AGES + VTG QP+ TW K K+I+ + + N L IL + G YT Sbjct: 6284 AGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTC 6343 Query: 1311 LVENKLGSRQAQVNLTVVDKP 1331 N +G L+V + P Sbjct: 6344 QATNDVGKDMCSAQLSVKEPP 6364 Score = 66.6 bits (161), Expect = 2e-10 Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 43/237 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F +L V G+ +C V+ P + W + + +++ +S + +++ Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTV 8212 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 K D G Y C A N+ G+ C+ Q+ + + +PP Sbjct: 8213 LKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER------------------LIPPSFTKR 8254 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 TV++ G S +L G+V G+QPIT W K + Sbjct: 8255 LSETVEETE-------------------------GNSFKLEGRVAGSQPITVAWYKNNIE 8289 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 IQ + + ++ N L + A G YT V N GS ++ + + PP Sbjct: 8290 IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 8346 Score = 66.6 bits (161), Expect = 2e-10 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%) Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134 G +D S+ Q ++ L D+ K L+++ S P ++W+ Sbjct: 26164 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 26223 Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 L+T ++ + S S++IE A D G Y +N A + V V D P Sbjct: 26224 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 26279 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254 PP T D T + A + + PE+ Sbjct: 26280 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 26304 Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312 G P+ ++ R + S+ V + N ++L+ + Y V Sbjct: 26305 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 26353 Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E Sbjct: 26354 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 26412 Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429 + K W + A +ST V L + EY FRV A N G S+P + + E+ E Sbjct: 26413 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 26472 Query: 1430 EPKDEVE 1436 P+ +++ Sbjct: 26473 PPEIDMK 26479 Score = 66.2 bits (160), Expect = 3e-10 Identities = 60/253 (23%), Positives = 98/253 (38%), Gaps = 44/253 (17%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 + + E P F+ P++ + + + V G + W ++ + + SG + Sbjct: 4762 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 4821 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146 T SL + A D G Y C+ +N G L F K+ Sbjct: 4822 ST-SLELFAAKATDSGTYICQLSNDVGTATSKATL-----FVKE---------------- 4859 Query: 147 PAVETRPSIWGECPPKFATKLGRVVV-KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205 PP+F K V+V + GQ F C+ITG P+ +V+W + Sbjct: 4860 -------------PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQ 4906 Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 + +S +G+ +I G ++ G Y C N +G AS S EL ++ +F+RE K Sbjct: 4907 KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK----EPPTFIRELK 4962 Query: 266 ATN----SDVRKE 274 SDV E Sbjct: 4963 PVEVVKYSDVELE 4975 Score = 65.9 bits (159), Expect = 4e-10 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 15/113 (13%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P+F + ++ V G +A F+C + G +V W KD + IR +QI Y E+ + L Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLT 8211 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL--------------IVETMEEGEG 1907 + V D +YTC AVN +G+ +CTA+L + ET+EE EG Sbjct: 8212 VLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEG 8264 Score = 65.9 bits (159), Expect = 4e-10 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 15172 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y A N G + +V V D P P L PV+ T + Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 15218 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P+ + + II+ +D K+ T QPI E+E K Sbjct: 15219 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 15254 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342 + +T L QE+ + ++ +NK G ++ + VD PP ++ Sbjct: 15255 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 15305 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400 S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y Sbjct: 15306 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 15365 Query: 1401 KFRVRAINVYGTSEPS 1416 +FRV+A+N G SEPS Sbjct: 15366 EFRVKAVNEIGESEPS 15381 Score = 65.9 bits (159), Expect = 4e-10 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 21535 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A N G A+ V V D P P V S+ V P Sbjct: 21536 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 21582 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I+Q E ++ W ++Q ++ Sbjct: 21583 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 21613 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346 K+T L E+ + ++ NK G + + V+ PDPP P + I Sbjct: 21614 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 21669 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+ Sbjct: 21670 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 21729 Query: 1405 RAINVYGTSEPSQES 1419 A N G S PS S Sbjct: 21730 MAENAAGISAPSPTS 21744 Score = 65.9 bits (159), Expect = 4e-10 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW + Sbjct: 22016 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 22074 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q Sbjct: 22075 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 22134 Query: 1418 ES 1419 S Sbjct: 22135 LS 22136 Score = 65.9 bits (159), Expect = 4e-10 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T Sbjct: 29342 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 29400 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K Sbjct: 29401 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 29454 Score = 65.5 bits (158), Expect = 5e-10 Identities = 54/234 (23%), Positives = 84/234 (35%), Gaps = 44/234 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F +KL+DVH G + +C+++ P + W +G LK + S ++ ++ I Sbjct: 7116 PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 7175 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + G Y C A N G A S ++ + + Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-------------------------- 7209 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +PP P + GES VTGT PI TW K ++ Sbjct: 7210 ------------------VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNRE 7251 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 I+ + K+ EN + LT+L + G YT N G L V + P Sbjct: 7252 IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305 Score = 65.5 bits (158), Expect = 5e-10 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89 +AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 30985 Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149 L+I +V ++D Y ATN G+ T L VE L Sbjct: 30986 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 31027 Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 PK +G V G++ +G+P P +TW KG + + V Sbjct: 31028 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 31076 Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268 L +GV + D G Y N G + EL + + R Sbjct: 31077 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 31130 Query: 269 SDVRKEVTNVISKESKLD 286 SDV ++ N+ E D Sbjct: 31131 SDVSRDSVNLTWTEPASD 31148 Score = 64.7 bits (156), Expect = 8e-10 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ K + G+ L ++ V P I W +G+ LK T + + + + + I Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 24371 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y A N AG A + V V + P PPV Sbjct: 24372 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 24413 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D + PP QI + +++ T TW Sbjct: 24414 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 24457 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331 + + +K+ + G++ + + EN+ G + V+ +P Sbjct: 24458 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 24505 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389 PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F Sbjct: 24506 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 24564 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 L EY+F+V A N+ G +PS+ SE + + P Sbjct: 24565 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 24606 Score = 64.7 bits (156), Expect = 8e-10 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%) Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68 S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R Sbjct: 32538 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 32596 Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126 GQ +++ R + + TF I +V D G Y+ N G ++ LT++ + Sbjct: 32597 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 32654 Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157 K + P K+ R +P ET+P+ + Sbjct: 32655 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214 PPK L KE + + +C + +VTW K L+ + +G Sbjct: 32715 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 32772 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 L+I+ + + D G Y C + G + + + Q S + + ++ SD + Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 32832 Query: 275 VTNVISK 281 + V K Sbjct: 32833 ESTVTRK 32839 Score = 64.3 bits (155), Expect = 1e-09 Identities = 52/224 (23%), Positives = 85/224 (37%), Gaps = 33/224 (14%) Query: 29 LTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 + + PA I+ L + G A E V G PE + W+++G+P+ + ++ + Sbjct: 4012 IVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFK-NN 4070 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 L ++ D G+YT E +N G+ T V+ + + F+ P Sbjct: 4071 VAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFT------------VLDRDIAPFFTKP 4118 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 + G C R CKI G +V+W K + S R Sbjct: 4119 LRNVDSVVNGTC-------------------RLDCKIAGSLPMRVSWFKDGKEIAASDRY 4159 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 ++ G LEI V+ +D G +TC N G S L +Q Sbjct: 4160 RIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203 Score = 64.3 bits (155), Expect = 1e-09 Identities = 69/307 (22%), Positives = 116/307 (37%), Gaps = 64/307 (20%) Query: 1054 KPDENLKS------ASKEELKKDVKND--VNCKRGHA-GTTDNEKR--SESQGTAPAFKQ 1102 + DENL++ A+ + L+ D+ + +C + GT + R + +P F Sbjct: 6216 RDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDI 6275 Query: 1103 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1162 K + V G+ +C V+ P I W+ + K ++ ++ G+ + I K Sbjct: 6276 KPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK 6335 Query: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATV 1222 D G Y C A ND G+ CS Q++V + Sbjct: 6336 GDSGQYTCQATNDVGKDMCSAQLSVKE--------------------------------- 6362 Query: 1223 KKKPAPKTPPKAAMPPQIIQFPEDQKV-RAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281 PP+ ++ E KV + GES++L K++G+ I +W + ++ ES Sbjct: 6363 --------------PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 6408 Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP-----DPPAG 1336 + + + LTI A E G Y N +G LTV P P G Sbjct: 6409 WKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVG 6468 Query: 1337 TPCASDI 1343 SD+ Sbjct: 6469 ALKGSDV 6475 Score = 64.3 bits (155), Expect = 1e-09 Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 7/114 (6%) Query: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 E+ +D+ +A + + PYF + + +E V G A CK++G P+ + W+K+ Sbjct: 7004 EAGQDICEALVSVLEP------PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEH 7057 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +R + +++ + ++ SL+I+ V D +Y+CKA NS+G +A L+++ Sbjct: 7058 TKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110 Score = 64.3 bits (155), Expect = 1e-09 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G+++ + +V G TW K K + + + + +L I A + G Y Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 17979 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +N G Q + V+D+P P +++ + T+SW +GGS + ++ + Sbjct: 17980 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 18038 Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425 E K W +A+ + +LL ++EY FRV A N G P+ E++ + Sbjct: 18039 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 18097 Query: 1426 -EKPEEPKD 1433 ++P EP++ Sbjct: 18098 IDRPGEPEN 18106 Score = 64.3 bits (155), Expect = 1e-09 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%) Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269 G +S+ V + P P PP PP I+ D SV L K TG PIT Sbjct: 20161 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 20209 Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++F R + K K+T L E+ + ++ N G + + Sbjct: 20210 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 20267 Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 V DP P G P +I +S+TL W YDGG + Y +E D +K+W + Sbjct: 20268 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 20327 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431 +F V DL+ +Y+FR+RA N G S PS+ +E ++ E P Sbjct: 20328 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376 Score = 63.9 bits (154), Expect = 1e-09 Identities = 67/331 (20%), Positives = 125/331 (37%), Gaps = 69/331 (20%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 +P F ++ + + V + ++L +V+ PP I W + L++ + + L S+ Sbjct: 4392 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQ 4451 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 I K + D G Y+C N+ G + CS +VT+ + Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARVTLRE--------------------------- 4484 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 PP I+ E G + + G+ PIT TW+K Sbjct: 4485 --------------------PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----- 1331 +I E +++++ N + L + +H G Y +N G ++ L+V + Sbjct: 4525 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 4584 Query: 1332 ----DPPAGTPCASDIRSS---SLTLSWY--GSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 D G P ++ S +T W+ G GS Y I + D+ + K ++ Sbjct: 4585 AVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS---KYKISVTDTVS-ILKIIS 4640 Query: 1383 TCRSTS----FNVQDLLPDHEYKFRVRAINV 1409 T + S F VQ+ + K R+ +++ Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDL 4671 Score = 63.9 bits (154), Expect = 1e-09 Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 14/163 (8%) Query: 1744 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1798 KW K G + I +++++ +S K +G T E + DV ++ + Sbjct: 4611 KWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT-------FEVQNDVGRSSCK 4663 Query: 1799 A-VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 A + + P F+K ++ ++ ++GS +C + G + WFKDDQ I S ++ Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + D L IS + G D YTC A N G C+ L V+ Sbjct: 4724 SF-HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765 Score = 63.9 bits (154), Expect = 1e-09 Identities = 53/230 (23%), Positives = 85/230 (36%), Gaps = 44/230 (19%) Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1161 +K + V V E + L+C V+ P + W +GK + +++ +S E ++ S I+ + Sbjct: 5145 EKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVM 5204 Query: 1162 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1221 +D G Y +ND G + C + V D ++PP T Sbjct: 5205 KQDSGQYTFKVENDFGSSSCDAYLRVLD------------------QNIPP------SFT 5240 Query: 1222 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281 K K G S+ + KV+G+ PI+ W K K+I S Sbjct: 5241 KKLTKMDKV--------------------LGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280 Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 ++ E L + E YT V N G LTV + P Sbjct: 5281 AKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPP 5330 Score = 63.9 bits (154), Expect = 1e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y + EN+ G Q + V + P PP G D+ +S++LSW + Sbjct: 23098 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 23156 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P Sbjct: 23157 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 23214 Score = 63.5 bits (153), Expect = 2e-09 Identities = 87/403 (21%), Positives = 150/403 (37%), Gaps = 89/403 (22%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ +LV HI+ L+V PA+ +++ +KEG T + P Sbjct: 8725 GNYRLVCGPHIASAKLTVIE-----------PAWERHLQDVTLKEGQTCTMTCQF-SVPN 8772 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 + W RNG+ + GR + + L I V ED+G+YTC+ + + + EL Sbjct: 8773 VKSEWFRNGRILKPQGRHKTEVEHK-VHKLTIADVRAEDQGQYTCKYED----LETSAEL 8827 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 +E P +F ++ +VV E Q F Sbjct: 8828 RIEAE---------------------------------PIQFTKRIQNIVVSEHQSATFE 8854 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV-VNGSG 240 C+++ VTW KG L S + + + IH V DD GVY+ + + G Sbjct: 8855 CEVS-FDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 8913 Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300 +A +AEL + T +++ E+ +S++ ++ Sbjct: 8914 EARSTAELYL----------------TTKEIKLELKPPDIPDSRVPIPTMPIRA------ 8951 Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360 PP PP L + ++ P ++ T ++ A +V +P+ Sbjct: 8952 ----VPPEEIPPVVAPPIPLLLPTPEEK---KPPPKRIEVTKKAVKKDAKKVVAKPKE-- 9002 Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403 ++P E K+P PP P + P + DV SKA +I Sbjct: 9003 ---MTPREEIVKKPPPP-TTLIPAKAPEI--IDVSSKAEEVKI 9039 Score = 63.5 bits (153), Expect = 2e-09 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%) Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271 S+ TV + P K P P + + +V+ E + G +V G + + W Sbjct: 22329 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 22387 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +K K K E G + + + G +G V P Sbjct: 22388 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 22438 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389 P G P A + +S+TL W +YDGGS + Y +E + W + + T F Sbjct: 22439 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 22498 Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432 V L+ DH Y+FRV A N G SEPS+ + T ++ + P+ Sbjct: 22499 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 22542 Score = 63.5 bits (153), Expect = 2e-09 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+ Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 26946 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G A + +V + D P P + T T+ +P P Sbjct: 26947 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 26993 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I++ E +V W SEH++ E Sbjct: 26994 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 27023 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 T + E+ + + NK G + + +VV K P PP G P + I + Sbjct: 27024 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 27080 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404 S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV Sbjct: 27081 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140 Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439 A+N G S+ SE + P P ++ ++D Sbjct: 27141 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 27177 Score = 63.2 bits (152), Expect = 2e-09 Identities = 33/95 (34%), Positives = 48/95 (50%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+ Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 I DV +D A KA+N GE + A L+V+ + Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383 P P P D SS++L W + DGGS ++ Y +E+ + WK + T Sbjct: 15704 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 15763 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D Sbjct: 15764 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 15818 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383 + KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ + Sbjct: 17110 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 17168 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432 C T + V L YKFRV A+N G S+P+ E V ++ E P+ Sbjct: 17169 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 17217 Score = 63.2 bits (152), Expect = 2e-09 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%) Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063 K V +S PLS P L+ K + TL L P+ G AK D + S Sbjct: 18788 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 18838 Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104 +EE D + + + + G + +K E++G A +Q L Sbjct: 18839 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 18898 Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 + + + GKKL ++ V P T W + T+ + + + S + I Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 18958 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215 + +D G Y A+N +G +V V DAP PP + Sbjct: 18959 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 19003 Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 ++DA P + + I+ E V G+ V VT T + Sbjct: 19004 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 19054 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 K I E++ +EN G L K+ AQ V +P Sbjct: 19055 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 19099 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388 T D + ++W DGGS + Y IE +W AN T RST Sbjct: 19100 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 19150 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 + L+ EY FR+ A+N G+S PS+ +E T P +P + EV D Sbjct: 19151 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 19200 Score = 63.2 bits (152), Expect = 2e-09 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%) Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 31638 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163 Y C+ N G EL V+G +++ +T+ + +T + E PP+F Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 31692 Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220 L G+ RF IT P+P VTW K ++P + + G+ L I Sbjct: 31693 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 31752 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + V DD YT + N G+ S A+L++ Sbjct: 31753 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782 Score = 62.8 bits (151), Expect = 3e-09 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%) Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143 D EK+ + P FK+KL + + +C+++ DP + W +GK L+ Sbjct: 1696 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1750 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203 + + E CS+ A D G+ C A N G S + V D E + E + Sbjct: 1751 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1806 Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263 + L + E A T K P I+ +PE +V GE+ +VTG Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866 Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323 W + I++S+ +V + L I+ + G + EN G + +V Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1925 Query: 1324 NLTVVDKPD 1332 L + + D Sbjct: 1926 KLEIQQRED 1934 Score = 62.8 bits (151), Expect = 3e-09 Identities = 54/228 (23%), Positives = 80/228 (35%), Gaps = 35/228 (15%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E P F+ +L G T + VRG VTW + + I G+ + G Sbjct: 3920 LKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGV 3978 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 L+I V GKYTC A N +G++ EL V+ Sbjct: 3979 AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE----------------------- 4015 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 P K + + V G + G P+ + W K PL S + Sbjct: 4016 -----------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4064 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256 +S KN + L+ + D G YT + N G +S ++ D A Sbjct: 4065 ISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIA 4112 Score = 62.8 bits (151), Expect = 3e-09 Identities = 58/246 (23%), Positives = 97/246 (39%), Gaps = 46/246 (18%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E P+FI + G TA F+ ++G VTW ++ IT D IR T Sbjct: 4482 LREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE------DDNIRMT 4535 Query: 89 F-----SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 F SL + + + GKY C+A N +G ++ + L+V+ Sbjct: 4536 FENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK------------------- 4576 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 PA T ++ + V +G K +G + W K L Sbjct: 4577 --EPATITEEAV-------------SIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTL 4621 Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263 ++ +S + + +L+I + D G YT V N G++S A +++ L SF ++ Sbjct: 4622 GSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-IIPPSFTKK 4680 Query: 264 TKATNS 269 K +S Sbjct: 4681 LKKMDS 4686 Score = 62.8 bits (151), Expect = 3e-09 Identities = 57/244 (23%), Positives = 86/244 (35%), Gaps = 35/244 (14%) Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83 V ++ L E P F+ +L + G A+ + + G V W + + + + Sbjct: 5601 VCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRIT 5660 Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 + +L + GKY C+ N G R+ L V Sbjct: 5661 FVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV-------------------- 5700 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 PAV K G + V G+ CK+ G P+ V W K L Sbjct: 5701 -LEPAV-------------IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTS 5746 Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263 S + S N + L I V + D G YT V N GK+S +A + + + SF R Sbjct: 5747 SQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSD-RAVPPSFTRR 5805 Query: 264 TKAT 267 K T Sbjct: 5806 LKNT 5809 Score = 62.8 bits (151), Expect = 3e-09 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386 KP PP P DI SS+ LSW YDGG +Q Y +E D + W Sbjct: 22837 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 22895 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 T+ V+ LL HEY FR+ AIN G E + V EK E P ++++ Sbjct: 22896 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 22946 Score = 62.4 bits (150), Expect = 4e-09 Identities = 53/248 (21%), Positives = 95/248 (38%), Gaps = 47/248 (18%) Query: 1099 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158 AF ++L D V GK ++L+ + P ++ W +G + T++ + C + I Sbjct: 5987 AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEIL 6046 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 + D G Y C +N+AG+ C V+ + PP TE Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGALVSTLE---------------------PPYFVTEL 6085 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 + P +AA+ G+SV L +V GT IT +W K ++ Sbjct: 6086 E-----------PLEAAV---------------GDSVSLQCQVAGTPEITVSWYKGDTKL 6119 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 + + + + N + L G YT EN +G+ ++ + ++ PP+ Sbjct: 6120 RPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFAR 6179 Query: 1339 CASDIRSS 1346 DI + Sbjct: 6180 QLKDIEQT 6187 Score = 62.4 bits (150), Expect = 4e-09 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 20843 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277 + + N +GK S ++++ LD+ +R T T V +TN Sbjct: 20844 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 20901 Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325 I ++ ++ A K C+ G S A N +P ++ Sbjct: 20902 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 20961 Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385 ++P ++ T S+++L P+P+ G ++ E +R + T T Sbjct: 20962 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 21016 Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425 GL Q + +A R P E + + P+ + + Q++ Sbjct: 21017 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 21076 Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 K +K V G PKP V W +G + +Q + A S L + + DSG Sbjct: 21077 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 21135 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522 Y TA N G++ T+QV + P F V D Sbjct: 21136 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 21174 Score = 62.4 bits (150), Expect = 4e-09 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569 AP +KD G+ L C + G P+P I W G+ + +R + + L Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628 + ED G YTC+A N +G+V S S+ LL P P P+ + Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 30638 Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688 + GS + + V G P P + W H +Q SE+ E L ++ V + Sbjct: 30639 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 30694 Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 G Y + N G V A+L V+ +P + P + A L S +IS Sbjct: 30695 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 30743 Score = 62.0 bits (149), Expect = 5e-09 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 I +D G +TC VN +G S S L++Q + F +ET A VT Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1049 Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309 + E K ++S + + + Q G P A Sbjct: 1050 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1081 Score = 62.0 bits (149), Expect = 5e-09 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329 +++ + V + TI + H + ++ +NK G + + + Sbjct: 16256 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315 Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383 P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A Sbjct: 16316 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 16374 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 S+ V L+ +Y+FRV AIN G S S+ T + P Sbjct: 16375 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 16422 Score = 62.0 bits (149), Expect = 5e-09 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y AKN +G A+ S V V D P P +L T+ + T+ Sbjct: 17978 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 18021 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 + P D G IT +++RK Q+ + Sbjct: 18022 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 18052 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340 + L A E+ + + ENK+G ++ + + +D+P P A Sbjct: 18053 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 18110 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 D + + L W YDGGS SY +E + W+ + + + T + V + + Sbjct: 18111 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 18169 Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 Y+FRV+ N G S+ + E+ V E ++P ++++S Sbjct: 18170 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 18208 Score = 61.6 bits (148), Expect = 7e-09 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143 T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++ Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194 +SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA + Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238 + E + R + + S ATV+ K P+ PPK + PP Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269 Query: 1239 QI 1240 I Sbjct: 270 SI 271 Score = 61.6 bits (148), Expect = 7e-09 Identities = 35/96 (36%), Positives = 46/96 (47%) Query: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 II D ++T A N G ++ + L VE +E Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1551 Score = 61.6 bits (148), Expect = 7e-09 Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 36/217 (16%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 E P+F+ P + + G+ + +G + W + + + SGG + + S Sbjct: 4204 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALES-S 4262 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 L ++ V D G YTC+ +N +G + + L F K+ Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANL-----FVKE-------------------- 4297 Query: 151 TRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 P F KL ++K+G + +CK+TG P ++TW + ++ S++ + Sbjct: 4298 ---------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRM 4348 Query: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246 S VL + V +D G Y C N +G S+ Sbjct: 4349 SFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSS 4385 Score = 61.6 bits (148), Expect = 7e-09 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%) Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364 + ++ EN G + + +D DPP G P +I ++TL W Y GG + Sbjct: 21331 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 21389 Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421 SY +E D N W + F V L D Y+FRV A N G S PS+ S+ Sbjct: 21390 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 21449 Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441 T + E PK +V+V D Sbjct: 21450 ITCRDDVEAPKIKVDVKFKD 21469 Score = 61.6 bits (148), Expect = 7e-09 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PAFK V G+ L + P + W + LK T + + ++I Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 22207 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A ED G Y N AG+A + V V D P PP + Sbjct: 22208 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 22249 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D T PP K G S+ + V T TW Sbjct: 22250 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 22291 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331 S ++ TI A R + GC + + EN+ G S TV P Sbjct: 22292 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 22338 Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387 P GTP + S+ + W DGGS V Y +E + + W +L T Sbjct: 22339 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 22398 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F L EY+FRV A N+ G +PS+ SE V P +P E + Sbjct: 22399 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 22457 Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475 ++ T + K++ + ++ L G++ Sbjct: 22458 QWKKPTYDGGSKITGYIVEKKELPEGRW 22485 Score = 61.6 bits (148), Expect = 7e-09 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P +K + VH E K+ + P TI W + L T + + S+S+ Sbjct: 22547 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 22603 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A+ D G Y AKN AG+ + V V D P PE P V+ Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 22646 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275 S T +K PP II + +++ E+ L V Q ++C Sbjct: 22647 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 22696 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330 KV G++ T + ++ NK G + + VV K Sbjct: 22697 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 22736 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388 PD P P + + S+ + W + DGGS + Y +E D W Sbjct: 22737 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 22795 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 V L+ +H+Y+FRV A N G SEPS S Sbjct: 22796 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 22826 Score = 61.6 bits (148), Expect = 7e-09 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W+K K + K + G + + + G +G V Sbjct: 24551 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 24601 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388 P P G P A I +++TL W +YDGGS + Y +E D + W + T Sbjct: 24602 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 24661 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 F V L+ D Y+FRV A N G SEPS S T ++ + P ++ Sbjct: 24662 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 24710 Score = 61.6 bits (148), Expect = 7e-09 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%) Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W + Sbjct: 28145 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 28200 Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435 + + R T F V L +EY+F V A N G S S L E P P V Sbjct: 28201 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 28260 Query: 1436 EVSDDDEKEPEVDY 1449 +V+D + +++ Sbjct: 28261 KVTDTSKTTVSLEW 28274 Score = 61.2 bits (147), Expect = 9e-09 Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Query: 1820 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1879 ++ G +AR CK++G P +V WFK+++ + ES ++ Y + L I+DV +D Sbjct: 3749 MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-YFVNSEAILDITDVKVEDSGS 3807 Query: 1880 YTCKAVNSLGEATCTAELIVE 1900 Y+C+AVN +G +C+ E++++ Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIK 3828 Score = 61.2 bits (147), Expect = 9e-09 Identities = 49/235 (20%), Positives = 90/235 (38%), Gaps = 48/235 (20%) Query: 1098 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 P F +KL+ + + G L+C+++ P ++W N L + ++ S+ + Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 + ED G + C A+N AG CS +V V + P SS PP++ T Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVF--------------SSFPPIVET 5528 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 +A V L +++GT P W K ++ Sbjct: 5529 LKNA---------------------------------EVSLECELSGTPPFEVVWYKDKR 5555 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 Q++ S+ K+ + + + IL G Y +N++GS + + + P Sbjct: 5556 QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 5610 Score = 61.2 bits (147), Expect = 9e-09 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC Sbjct: 25002 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 25058 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 + F V L + EY FR+ AIN G EP+ E+ E P+ E++ Sbjct: 25059 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 25110 Score = 61.2 bits (147), Expect = 9e-09 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 +HV G+ + L ++ PP W G L+ ++ + + + ++I + D G Sbjct: 29748 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 29807 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223 Y KN G + +V + D P P+ E DAT + Sbjct: 29808 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 29852 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P+ A + +++ + + G + ++ +T + KF + + +E+ Sbjct: 29853 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 29902 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 + + A + G Y +++++ ++ + + P PP T D+ Sbjct: 29903 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 29943 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396 +TL+WY DGGS V Y +E W NK + RST L Sbjct: 29944 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 29998 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432 EY+ RV AIN G+ +PS+ S+ + KP+ P+ Sbjct: 29999 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 30040 Score = 60.8 bits (146), Expect = 1e-08 Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1861 +E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396 Query: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 D L I++ +D+ YT A N++G+ + TA L +E E E E+E Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447 Score = 60.5 bits (145), Expect = 2e-08 Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 41/238 (17%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F Q L V V+EG+ + L C V P I W G+ +K + S + + Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLEL 8405 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 D G Y C A N AG S+ TK Sbjct: 8406 RDVAKADSGDYVCKASNVAG---------------SDTTK-------------------- 8430 Query: 1218 SDATVKKKPA--PKTPPKAAMPPQIIQFPEDQKVRAGE--SVELFGKVTGTQPITCTWMK 1273 S T+K KPA P T KAA+ ++ E Q +R E + KV G W K Sbjct: 8431 SKVTIKDKPAVAPATK-KAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 8489 Query: 1274 FR-KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 + +Q+ + + + + +KL I + G Y + N+ G ++ VNL V ++ Sbjct: 8490 GKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 8547 Score = 60.5 bits (145), Expect = 2e-08 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T Sbjct: 19589 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 19647 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 F V L+ D +Y+FRV A+N G S+PS Sbjct: 19648 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 19676 Score = 60.5 bits (145), Expect = 2e-08 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 + ++P PP D SS L+W +DGGS + Y +E+ + W E Sbjct: 28540 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 28598 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 + +F V+ L+ EY+FRV+A N G SEP + + E EP Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 28645 Score = 60.5 bits (145), Expect = 2e-08 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P + + K + + C++ G P P++ W+ G + Q ++ D +H L Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 30591 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 ++ D G Y+C A+N G++ S L ++ A + P + K + G L Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 30648 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589 G PVP +TW + +Q + + T E H+ ++ + H G Y N Sbjct: 30649 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G V V + +K P KPT PI ++ L + + +S Sbjct: 30709 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 30745 Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702 PP + W+ N E +E ++ + C E+ G Y A N+ G Sbjct: 30746 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 30805 Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748 + +V+ ++ P + +P KP ++TA SC +A P Sbjct: 30806 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 30847 Score = 60.5 bits (145), Expect = 2e-08 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G Sbjct: 32847 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 32905 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 F L IH D G YTC N +G+ + +LT++ Sbjct: 32906 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942 Score = 60.1 bits (144), Expect = 2e-08 Identities = 72/302 (23%), Positives = 123/302 (40%), Gaps = 31/302 (10%) Query: 313 QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER- 371 +P+P E+++++ K P TP+ ++ +T+ + E +AP P G + Sbjct: 11020 EPKPKPEAEVKTIKPPPVEPEPTPI----AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKG 11075 Query: 372 --KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQ 429 K+ P A +PG G + +A P Q + KF + + + E++ Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEA-----PFTYQLKAVPLKFVKEIKDIILTESE 11130 Query: 430 TVK----FRCEVSGIPKPEVA-WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V F C VS P + W +G+ +R + D L ++ + D+G Sbjct: 11131 FVGSSAIFECLVS--PSTAITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGE 11187 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+C + + + L VE L V V ++ ++ V++GQ L C + Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCELNKER--D 11241 Query: 545 ITWLLNGQPIQYARSTCEAGVA----ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W +G+ + GV L I DA D GTYT ENA + CS+ V V Sbjct: 11242 VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKV 11300 Query: 601 HE 602 E Sbjct: 11301 VE 11302 Score = 60.1 bits (144), Expect = 2e-08 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384 V KP PP G P D SS++++W YDGGS + Y +EI W+ + A Sbjct: 21753 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 21811 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 ++TS+ + L + EYK R+ A+N G EP+ Sbjct: 21812 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 21843 Score = 60.1 bits (144), Expect = 2e-08 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W K K + MKV + G Y + EN G + + V Sbjct: 25633 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 25681 Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386 DP P G P ++I S++L W YDGG+ + Y +E + + W + + Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 25741 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D Sbjct: 25742 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 25797 Score = 59.7 bits (143), Expect = 3e-08 Identities = 52/241 (21%), Positives = 87/241 (36%), Gaps = 54/241 (22%) Query: 1084 TTDNEKRSESQGTA------PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGK 1136 T NE S S P+F +K+ ++ G+ L C++ P + W N K Sbjct: 3717 TASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNK 3776 Query: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1196 L + + + S + I ED G Y C A ND G CS ++ + + Sbjct: 3777 ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------- 3829 Query: 1197 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256 PP I+ E + G + Sbjct: 3830 ----------------------------------------PPSFIKTLEPADIVRGTNAL 3849 Query: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1316 L +V+GT P +W K +KQI+ S+ ++ + ++ L I + G Y +V N++ Sbjct: 3850 LQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEV 3909 Query: 1317 G 1317 G Sbjct: 3910 G 3910 Score = 59.3 bits (142), Expect = 3e-08 Identities = 73/351 (20%), Positives = 128/351 (36%), Gaps = 64/351 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+F +K++ G Q + P T+ W + + I ++ E ++ S+ + Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA----------------PASENTK---A 1198 + G Y C AKNDAG CS ++V + PA+ K Sbjct: 4546 SGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGT 4605 Query: 1199 PEMKSRRPKSSLPPVLGTESDATV------------KKKPAP-----------KTPPKAA 1235 E+ ++ K LG++ +V +KK + ++ KA Sbjct: 4606 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 4665 Query: 1236 M-------PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288 + PP + + G ++L V G+ PI+ W K ++I SE K Sbjct: 4666 INVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF 4725 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP---DPPAGTPCASDIR- 1344 +N + L I G YT NK G Q +LTV + P + P + R Sbjct: 4726 HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRV 4785 Query: 1345 --------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1387 ++ +T+ W+ + + S + +W T EL ++T Sbjct: 4786 QLKALVGGTAPMTIKWFKDNKELHSGA---ARSVWKDDTSTSLELFAAKAT 4833 Score = 59.3 bits (142), Expect = 3e-08 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 PYF K + ++V G +A C++ G P+ V W+K D +R + +++ + + +L+ Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLV 8019 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + V +D +Y CKA NS+GE + + L V+ Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051 Score = 58.9 bits (141), Expect = 5e-08 Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 2/128 (1%) Query: 1772 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1831 ++ G +S N LE+ E + +E E + P + I LEV G A+F C+ Sbjct: 3420 NAVGQVSSTANLS-LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478 Query: 1832 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1891 I+ P+ WFK + I ES I + + SL I D +YTCKA N G Sbjct: 3479 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSV 3537 Query: 1892 TCTAELIV 1899 +CTA L V Sbjct: 3538 SCTATLTV 3545 Score = 58.9 bits (141), Expect = 5e-08 Identities = 51/237 (21%), Positives = 86/237 (36%), Gaps = 44/237 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F +L+ + A G + LQCQV+ P T+ W L+ T ++ ++ Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 6138 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 K D G Y C A+N +GT Sbjct: 6139 NKVNINDSGEYTCKAENS--------------------------------------IGTA 6160 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 S TV + + +PP + +D + G V L ++ G+ PI W + Sbjct: 6161 SSKTVFR------IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVL 6214 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 +++ E+++ +N + L IL H G Y+ N LG+ + LT + P Sbjct: 6215 LRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP 6271 Score = 58.9 bits (141), Expect = 5e-08 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 4/157 (2%) Query: 1744 KWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEE 1803 KW K G + + + ++ + +SG K +P S E + V + A + Sbjct: 7618 KWFKDGKELTSDNKYK-ISFFNKVSGLKIINVAP-SDSGVYSFEVQNPVGKDSCTASLQV 7675 Query: 1804 KPH-VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 V P F++ +++ + GS+ +CK+ G P V WF + I R +Q D Sbjct: 7676 SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TD 7734 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 C+L ++ + D YTC A N G C+A L V Sbjct: 7735 NTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 7771 Score = 58.9 bits (141), Expect = 5e-08 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%) Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189 W T+K TK + EGSL +++ A+N GQ++ + ++D Sbjct: 14130 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 14173 Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249 + +++T + PP D T + PPK I ++ ++K Sbjct: 14174 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 14224 Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 R G W+K K + +V + G+++ + G Sbjct: 14225 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 14265 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 +G + ++ P P P +D + ++W +GGS + Y Sbjct: 14266 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 14319 Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE Sbjct: 14320 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 14379 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456 + +P ++E D E E V +R V + T Sbjct: 14380 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 14417 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G+ L+ V P TI W K ++ + + + ++ A+ D G Y Sbjct: 23637 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 23696 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 A N AG V V D P P V G S+ K Sbjct: 23697 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 23739 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288 +PP I + +++ E+ L V ++ +T Sbjct: 23740 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 23775 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343 N K+T L E+ + ++ NK G + + V+ K P PP ++I Sbjct: 23776 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 23830 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401 S+T+ W DGGS + Y +E D + W + R T V L DHEY+ Sbjct: 23831 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 23890 Query: 1402 FRVRAINVYGTSEPS 1416 FRV A N G EPS Sbjct: 23891 FRVSAENAAGVGEPS 23905 Score = 58.5 bits (140), Expect = 6e-08 Identities = 60/273 (21%), Positives = 100/273 (36%), Gaps = 48/273 (17%) Query: 1061 SASKEELKKDVKNDVN--CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQ 1118 +AS E ++ D+ + N C+ ++ + + + P+F K V G + L+ Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLK 4226 Query: 1119 CQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178 P TI W K L + +++E S+ + D G Y C N AG Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG 4286 Query: 1179 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238 ECS + V + AT +K P Sbjct: 4287 VECSANLFV-----------------------------KEPATFVEKLEP---------- 4307 Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298 Q ++ G++ +L KVTGT PI TW ++I+ES ++ E+ + L + Sbjct: 4308 -------SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360 Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 E G Y +N+ GS + V + P Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 4393 Score = 58.5 bits (140), Expect = 6e-08 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + +F C ++ + V W +G + + ++ D H L + ++ D G Sbjct: 11497 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 11553 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ + +G+ + + RL V + F S L+D V EG+ C + + Sbjct: 11554 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 11603 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604 + W N + +R+ + + H + + E L +S V E Sbjct: 11604 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 11651 Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664 S+ + + L P F L D ++ ++T+ +VS + P V W +G EI Sbjct: 11652 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 11702 Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724 S + + G + L I++ +D G Y C+ G +T+A +TV+ + + Sbjct: 11703 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 11753 Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781 KP V +G++ ++ P VH W G+ L + E++++ L+L Sbjct: 11754 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 11809 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827 Q G+ N + +V + S + + REP + Sbjct: 11810 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 11869 Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884 L G + G DR+ ++ G + ++ ED + + +HT Sbjct: 11870 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 11922 Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938 E IR + + L +D+ K+ V T LS D+++ + + N QR ++V Sbjct: 11923 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 11974 Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997 S ++E K HS + F+ L+ TS+ V + + KL G Sbjct: 11975 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 12017 Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055 + + + VE + + + S PV K + +KP NA Sbjct: 12018 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 12064 Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112 +K+ K+ LKK +K+D+ GT + + + + L V V E Sbjct: 12065 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 12121 Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + ++S D W L G+ L T + +EG + S+ + + G Sbjct: 12122 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 12174 Score = 58.5 bits (140), Expect = 6e-08 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%) Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147 R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + + Sbjct: 24699 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 24758 Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207 ++ ++ + D G Y N G V V D P P Sbjct: 24759 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 24805 Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267 V G ++ P A + II+ E ++ Sbjct: 24806 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 24847 Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 +W + ++Q + K+T L E+ + ++ NK G + + V Sbjct: 24848 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 24893 Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381 KP P TP S I S+ ++W DGG+ ++ Y +E D W + Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 24953 Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 T V L H Y+FRV A N G EPS+ S Sbjct: 24954 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 24991 Score = 58.5 bits (140), Expect = 6e-08 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T + Sbjct: 30531 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 30589 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 L + +ED G YTC ATN G + + +L ++ + G P+ K G Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 30640 Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210 G R GRP P +TW G LQ S +++ Sbjct: 30641 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 30678 Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268 L + V + G Y + N G ++ IQ D V E N Sbjct: 30679 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 30738 Query: 269 SDV 271 S V Sbjct: 30739 SAV 30741 Score = 58.5 bits (140), Expect = 6e-08 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386 +KP P G P + + S ++W + DGG+ +++Y +E + W + T R Sbjct: 30823 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 30881 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE Sbjct: 30882 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 30932 Score = 58.5 bits (140), Expect = 6e-08 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156 P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++ Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214 I LPED G Y+ A N AG C + V+ + K+ E R + + L Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 31914 Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250 GTES +A V KPA T K +I + E++K+R Sbjct: 31915 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 31969 Score = 58.2 bits (139), Expect = 8e-08 Identities = 42/230 (18%), Positives = 82/230 (35%), Gaps = 47/230 (20%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+F ++L++ G +L+C+V+ P ++ W + + + ++C++ + Sbjct: 5800 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 5859 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 D G Y CVA N AG EC +TV + P+ Sbjct: 5860 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPS------------------------- 5894 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 ++ PE +V G++V + GT P W + ++ Sbjct: 5895 ----------------------FVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARE 5932 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 + + + + + ++L + G YT +V N G L V Sbjct: 5933 LVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 5982 Score = 58.2 bits (139), Expect = 8e-08 Identities = 55/284 (19%), Positives = 97/284 (34%), Gaps = 65/284 (22%) Query: 1057 ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116 +N+ + L + C + +D + + P+F ++ + + V GK + Sbjct: 5852 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVT 5911 Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE---------DRGL 1167 + PP + W + L +G C++ E + E G Sbjct: 5912 FTSVIRGTPPFKVNWFRGARELV---------KGDRCNIYFEDTVAELELFNIDISQSGE 5962 Query: 1168 YKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPA 1227 Y CV N+AGQA C+ ++ V + Sbjct: 5963 YTCVVSNNAGQASCTTRLFVKE-------------------------------------- 5984 Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 P ++ D V G+S+ L TGT PI+ TW K I SE + Sbjct: 5985 ---------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIV 6035 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +E L IL + + G Y+ +EN+ G ++ ++ P Sbjct: 6036 TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 6079 Score = 58.2 bits (139), Expect = 8e-08 Identities = 49/237 (20%), Positives = 84/237 (35%), Gaps = 44/237 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F + L+ V G+ LQC+V P I W L++ + + ++ S+ I Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 7079 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 K D G Y C A N G S + + K+R+ Sbjct: 7080 NKVDHSDVGEYSCKADNSVGAVASSAVLVI--------------KARK------------ 7113 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +PP + +D G V ++ G++P+ +W K Sbjct: 7114 ------------------LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVL 7155 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 +++ +++ N + L IL Q H G Y N LG+ + L + + PP Sbjct: 7156 LKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 7212 Score = 57.8 bits (138), Expect = 1e-07 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1867 PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +IS DD +YT N GE + +A L+ E Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174 Score = 57.8 bits (138), Expect = 1e-07 Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 50/233 (21%) Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT---KFIILSQEGSLCSVSIE 1158 +K + V G+ L+C+V+ P ++ W +GK L ++ KF ++ SL +S+E Sbjct: 5708 EKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE 5767 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 + +D G Y +N+ G++ C+ V V D Sbjct: 5768 R---QDAGTYTFQVQNNVGKSSCTAVVDVSD----------------------------- 5795 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 A+PP + ++ G S L KV G+ PI+ W + +I Sbjct: 5796 ---------------RAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKI 5840 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 + S+N L + + G YT + N GS + + LTV + P Sbjct: 5841 VSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 5893 Score = 57.8 bits (138), Expect = 1e-07 Identities = 51/227 (22%), Positives = 84/227 (37%), Gaps = 41/227 (18%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 + + E P+F P ++ + G + F +RG P +V W + + + G C I Sbjct: 6828 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGE----SCNIS 6883 Query: 87 ---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 L + V + G Y+C TN +G+ T L F K+ Sbjct: 6884 LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHL-----FVKE------------- 6925 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 P F +L V+ G TG P V+W+K + Sbjct: 6926 ----------------PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQ 6969 Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 S R S++ +LEI +D Y+CL+ N +G+ A +S+ Sbjct: 6970 SERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV 7016 Score = 57.8 bits (138), Expect = 1e-07 Identities = 87/371 (23%), Positives = 148/371 (39%), Gaps = 50/371 (13%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 V KP PP D +S+TL+W YDGGS + Y +EI + + W+ + Sbjct: 23917 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 23975 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSELR 24031 Query: 1445 PEVDYR---TVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVW----------A 1491 + R + I+ K +I G+F + +EK A Sbjct: 24032 KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDA 24090 Query: 1492 GKF-FKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI 1550 GK+ K ++ ++ + +++ P+ + + ++ A +V I+ GG + Sbjct: 24091 GKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNY 24150 Query: 1551 IDEDFELTERECIKYMRQISE---GVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFG 1607 + + E T + + S+ VE + + I + + EN V G ++ +D Sbjct: 24151 VIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV---GVPVETVDAV 24207 Query: 1608 LARRLE-----------NAGSLKVLFGTPEF-----VAPEVINYEPIGYATDMWSI---G 1648 A + S +++ PE V V+ +P G T+ WSI Sbjct: 24208 KAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG--TEKWSIVAES 24265 Query: 1649 VICYILVSGLS 1659 +C +V+GLS Sbjct: 24266 KVCNAVVTGLS 24276 Score = 57.8 bits (138), Expect = 1e-07 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%) Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V Sbjct: 24187 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 24246 Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 Y +E+ + W +A + + V L EY+FRV+A N G S+P Sbjct: 24247 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 24296 Score = 57.8 bits (138), Expect = 1e-07 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Query: 1790 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD Sbjct: 31773 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 Q + + +I ++ +L I D +D Y A N+ G +C A L VE + + Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892 Query: 1907 GEGEEEEE 1914 E + +EE Sbjct: 31893 QEFKSKEE 31900 Score = 57.4 bits (137), Expect = 1e-07 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1867 P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 ++ + +D A YTC+A N G AT +A L VE E Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332 Score = 57.4 bits (137), Expect = 1e-07 Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 47/237 (19%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F +K+ D+ G+ + LQ V P ++ W + ++ I +S + + I Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 3983 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 G Y C+A+N+AG Q +V + E Sbjct: 3984 PDVQISFGGKYTCLAENEAGS-----QTSVGELIVKE----------------------- 4015 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 P +II+ E +V AG+ L V GT + W K + Sbjct: 4016 -------------------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4056 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 + S+ ++ N ++L +A G YT + N++GS + TV+D+ P Sbjct: 4057 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 4113 Score = 57.4 bits (137), Expect = 1e-07 Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 2/93 (2%) Query: 1809 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 P F K + +V +G + + +CKI G P+ +V WF++D + ES + + + + L Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I++ +D Y C+A N +G+A+C+ L V+ Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455 Score = 57.4 bits (137), Expect = 1e-07 Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F K +E ++G+ +C+++G P V W+KD + +R + ++I E+ S+ Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIH 7457 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I +V D +Y CKA N +G TC + ++ Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489 Score = 57.4 bits (137), Expect = 1e-07 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358 QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D Sbjct: 25263 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 25322 Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q Sbjct: 25323 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381 Score = 57.0 bits (136), Expect = 2e-07 Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 8/160 (5%) Query: 1744 KWQKTGNAVRAIGRLSSMAMISGLSG-RKSSTGSPTSPLNAEKLESEEDVSQ--AFLEAV 1800 KW K G + R SM+ + ++ R S S K+E++ S A+L + Sbjct: 5173 KWLKDGKQI-VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL 5231 Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 + P P F+K + ++ V GS+ +CK+ G WFKD + I S +++ Sbjct: 5232 DQNIP---PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288 Query: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 E + SL ++++ +D A YTCK N G+ C+ L V+ Sbjct: 5289 E-RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327 Score = 57.0 bits (136), Expect = 2e-07 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 PYF + LE G + C++ G P+ V W+K D +R + ++ Y + +L+ Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLV 6137 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEAT 1892 + V +D +YTCKA NS+G A+ Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTAS 6161 Score = 57.0 bits (136), Expect = 2e-07 Identities = 55/269 (20%), Positives = 96/269 (35%), Gaps = 62/269 (23%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F ++L D V G ++L+ + PP ++ W + + ++ ++ + I + Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219 + ED Y C+ +N+AGQ C V+V + Sbjct: 6989 STIEDYAQYSCLIENEAGQDICEALVSVLE------------------------------ 7018 Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279 PP I+ E + GE L KV GT I +W K +++ Sbjct: 7019 -----------------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7061 Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----- 1334 + K++ N + L I G Y+ +N +G+ + L + + PP Sbjct: 7062 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARK 7121 Query: 1335 -------AGTPCASDIR---SSSLTLSWY 1353 G P A + R S L +SWY Sbjct: 7122 LKDVHETLGFPVAFECRINGSEPLQVSWY 7150 Score = 57.0 bits (136), Expect = 2e-07 Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 2/93 (2%) Query: 1809 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 P F K + +V + R++CKI G P+ +V+W+KD+ I+ES F++ + D L Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVL 7363 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + ++ +D YTC+A N+ G A+ + L V+ Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396 Score = 56.6 bits (135), Expect = 2e-07 Identities = 50/225 (22%), Positives = 79/225 (35%), Gaps = 32/225 (14%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 + + E I P + + G E V G PE W ++G+ +++ + + I Sbjct: 6639 LTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITF-IN 6697 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146 SL I D+G Y+ E N G TV + V DR Sbjct: 6698 KVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS-----------------DRI-- 6738 Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206 PP F KL V G C+++G V W + + + Sbjct: 6739 ------------VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPK 6786 Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 S + L + + D G+YTC+ N +G SA L++Q Sbjct: 6787 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831 Score = 56.6 bits (135), Expect = 2e-07 Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 41/224 (18%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 E F+ + ++ G+ E G P V+W ++ I+ R C I T Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSER----CSITMTEK 6980 Query: 91 LVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 I + E ED +Y+C N +G + + + +VS Sbjct: 6981 STILEILESTIEDYAQYSCLIENEAG---------------QDICEALVS---------- 7015 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 +E PP F L V G+ CK+ G P+ +++W K + L+ + Sbjct: 7016 VLE---------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAY 7066 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 + KN + L I+ V+ DVG Y+C N G + SA L I+ Sbjct: 7067 KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 16593 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 +AKN+AG+ + + V V D P T P + S Sbjct: 16594 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 16633 Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 ++ F PED G PIT ++ +++ V Sbjct: 16634 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 16667 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341 + T+ Q + + EN +G + +A V + P+ P Sbjct: 16668 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 16726 Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399 ++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L Sbjct: 16727 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 16786 Query: 1400 YKFRVRAINVYGTSEPS 1416 Y++RV A+N+ G +PS Sbjct: 16787 YEYRVSAVNIVGQGKPS 16803 Score = 56.6 bits (135), Expect = 2e-07 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + ++ V P T+ W + LK T+ + + ++I + + D G Y Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A+N G+ + V D P PP + D Sbjct: 21140 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 21170 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 + + F D G V Q + TW++ + + + Sbjct: 21171 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 21219 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 ++LT Q + + +N+ G + +V P PP GTP + + Sbjct: 21220 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 21273 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV Sbjct: 21274 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 21333 Query: 1405 RAINVYGTSEPSQESE 1420 A N+ G S+PS+ SE Sbjct: 21334 IAENMAGKSKPSKPSE 21349 Score = 56.6 bits (135), Expect = 2e-07 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%) Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115 E L ++ E + KND A ++ K + + TA Q + G Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 28665 Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175 + +S P + W L LK T + ++ +++++ ++ D G Y +N Sbjct: 28666 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 28725 Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235 AG S V V P P + V +++ V PK Sbjct: 28726 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772 Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 + I++ E T W ++ ++ K+ Sbjct: 28773 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 28802 Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351 T L E+ + + EN+ G S+ + + + P P P + + ++++++ Sbjct: 28803 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 28860 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N Sbjct: 28861 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 28920 Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 G S+ S+ S + + P + EV+D Sbjct: 28921 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 28949 Score = 56.2 bits (134), Expect = 3e-07 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F++ + ++GS C+I G P EVVW KD + +R S+ F+I + + SL Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLH 6516 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897 I ++ D +Y CKA N +G TC+ + Sbjct: 6517 ILNLEASDVGEYHCKATNEVGSDTCSCSV 6545 Score = 56.2 bits (134), Expect = 3e-07 Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%) Query: 1791 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1850 +VS + V E+K + P FS+ +RD++ G FDC I G V W+KD + ++ Sbjct: 8041 EVSASTFLTVQEQK--LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098 Query: 1851 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +S + Q + D +L I +Y+C A N +G A+ +A LI+ Sbjct: 8099 DSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146 Score = 56.2 bits (134), Expect = 3e-07 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387 P P P +D S +L+W YDGG + Y +E ++ W + T R T Sbjct: 20672 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 20731 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+ Sbjct: 20732 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 20782 Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469 RT+ + + F I+ R Sbjct: 20783 -RRTLVVRAGLSIRIFVPIKGR 20803 Score = 55.8 bits (133), Expect = 4e-07 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%) Query: 1777 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1834 P +++E E ++ A ++K KP + V+EG ARF C++ G Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866 Query: 1835 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1924 Query: 1895 AELIVETMEE 1904 +L ++ E+ Sbjct: 1925 VKLEIQQRED 1934 Score = 55.8 bits (133), Expect = 4e-07 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 GC + ++ EN+ G + V + P PP DI S+++L+W +DG Sbjct: 20934 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 20992 Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 GS + Y IE + W + T + V++L EY F+V A+N G S P +ES Sbjct: 20993 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 21051 Query: 1420 ELTTVGEKPEEPK 1432 V E+ P+ Sbjct: 21052 RPVIVKEQTMLPE 21064 Score = 55.5 bits (132), Expect = 5e-07 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 AP F Q LQ V V EG + +S P + W +G+ + T+ + +S Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 ++I + G Y A N +GQA + ++ V A Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP +Q + VR G V L +VTG + + Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 +IQ S ++ + L I A E G Y++ N +G + L V + + P Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200 Query: 1335 A 1335 A Sbjct: 201 A 201 Score = 55.5 bits (132), Expect = 5e-07 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + L G AA+F C + G P E +W KD ++ S +++I D + L Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS-DAENKHILE 3609 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +S++ D Y+CKA N G C AELI+ Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII 3640 Score = 55.5 bits (132), Expect = 5e-07 Identities = 67/319 (21%), Positives = 123/319 (38%), Gaps = 53/319 (16%) Query: 1082 AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT 1141 + + D R Q P+F +KL + G + ++C+VS P + W +GK + T+ Sbjct: 5221 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280 Query: 1142 -KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 K+ ++ E S+ S+ + ED Y C N AG CS +TV + P S K P Sbjct: 5281 AKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-PPSFLVK-PG 5337 Query: 1201 MKSRRPKSSL---------PP---------------------VLGTESDATVKKKPAPKT 1230 + P S++ PP + G+ S + A KT Sbjct: 5338 RQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKT 5397 Query: 1231 PPKAAM------------------PPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTW 1271 PP+ ++ E K V+AG+S L K+ G+ I W Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 + ++ S+ ++ ++ + + + E G + +N GS + V + P Sbjct: 5458 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 5517 Query: 1332 DPPAGTPCASDIRSSSLTL 1350 + P ++++ ++L Sbjct: 5518 VFSSFPPIVETLKNAEVSL 5536 Score = 55.5 bits (132), Expect = 5e-07 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 +P P+F ++V+ G +A F+C + G + W KD++ IR ++ I G Sbjct: 6266 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC--VG 6323 Query: 1864 NC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 N L I V D +YTC+A N +G+ C+A+L V+ Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361 Score = 55.5 bits (132), Expect = 5e-07 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1863 P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G Sbjct: 30924 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 30983 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 LII+ V DD Y +A N G + TA L VE Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020 Score = 55.5 bits (132), Expect = 5e-07 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F R + EG F C+I G P PE+ WFK++ I S + I + SL Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 33192 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I + D KYT KA N G+ + TA L+V + E Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228 Score = 55.1 bits (131), Expect = 7e-07 Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 5/159 (3%) Query: 1742 RRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1801 R W GN + AI + ++ I GL+ + S G+ E+ D A Sbjct: 4892 RVSWYLDGNEITAIQK-HGISFIDGLATFQIS-GARVENSGTYVCEARNDAGTA--SCSI 4947 Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1861 E K P F + ++ +EVV+ S +C++ G P EV W K+++ IR S+ + + D Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DR 5006 Query: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +L I+ D +Y C N G +C+ + ++ Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045 Score = 55.1 bits (131), Expect = 7e-07 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P FS +E ++ + +C++ G P EVVW+KD + +R S+ ++I ++ + S+ Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIH 5575 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATC 1893 I +V D +Y CKA N +G TC Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVGSDTC 5600 Score = 55.1 bits (131), Expect = 7e-07 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388 P PP P +D SS L W DGGS V Y +E + + W++ R T Sbjct: 16422 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 16479 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D Sbjct: 16480 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 16532 Score = 55.1 bits (131), Expect = 7e-07 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386 KP P P D + L W DGGS + Y +E W + R Sbjct: 17802 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 17861 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 +F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D Sbjct: 17862 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916 Score = 55.1 bits (131), Expect = 7e-07 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268 TES + K K P PP++ + +++ E G +TG + + Sbjct: 18382 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 18439 Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328 W+ K MKV+N +H + + EN++G + + V Sbjct: 18440 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 18488 Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378 DP P G P D S+TL W YDGG+ + Y +E+ S ++ W Sbjct: 18489 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548 Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 K A F V L + EY+FRV A N G P++ E E E P+ ++ Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608 Query: 1436 EVS 1438 + S Sbjct: 18609 DAS 18611 Score = 55.1 bits (131), Expect = 7e-07 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399 D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L + Sbjct: 29645 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 29704 Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424 Y FR+RA N G SEP + TV Sbjct: 29705 YLFRIRAQNEKGVSEPRETVTAVTV 29729 Score = 55.1 bits (131), Expect = 7e-07 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567 AP F L++ V + L C V G P P + W G+ I +Y + G + Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I +D Y A N G VS +A + V P+K P L+ Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 31032 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP Sbjct: 31033 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 31088 Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734 +D G Y A N G + V V +P G + +S+ + AS Sbjct: 31089 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 31148 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760 G S + + + WLR G+A Sbjct: 31149 GGSKITNYIVEKCATTAERWLRVGQA 31174 Score = 54.7 bits (130), Expect = 9e-07 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383 PDPP I +++ LSW DGGS V Y +E WD + + W++ Sbjct: 16012 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 16070 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431 F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 16117 Score = 54.7 bits (130), Expect = 9e-07 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101 + G + K + G P P + W+++ + + + L C + T L + + DR Sbjct: 26885 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 26940 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 G Y + N G+ T+ + + G P+ KT+ E +W Sbjct: 26941 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 26992 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204 K+ +V++ + R + + +KGN + +P Sbjct: 26993 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 27052 Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260 SV KN G+ + + + VV A +++S ++ D + + Sbjct: 27053 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 27112 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320 + K T D R++VT + + + C+ G P +P Sbjct: 27113 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 27158 Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378 K D P + + T SSITL ++ + G V GEE + Sbjct: 27159 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 27218 Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421 T + PG+ VS A + P+E P+ Sbjct: 27219 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 27278 Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478 S K + V+ G P P V W + + GS Y E+ S L + Sbjct: 27279 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 27334 Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528 TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G Sbjct: 27335 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 27393 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 ++ + + TW + + + D + + LAEN Sbjct: 27394 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 27444 Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637 +G E PV ++ API + D DG Sbjct: 27445 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 27490 Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697 V V E W H G I ++ + Q Q L + + G Sbjct: 27491 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 27547 Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 + G + + ++ E P VT +G +V + G P P++ WL+D Sbjct: 27548 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 27600 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817 G L K++ + E+ TL +K + H G+Y ++L N V C V + + Sbjct: 27601 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 27657 Query: 818 ALPRG 822 + P+G Sbjct: 27658 SKPKG 27662 Score = 54.7 bits (130), Expect = 9e-07 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%) Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + + EN G S T+ P P GTP D+ ++TL W DGGS + Sbjct: 27829 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 27888 Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419 YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S Sbjct: 27889 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944 Query: 1420 ELTTVGEKPEEP 1431 + ++ P Sbjct: 27945 GIIMTRDENVPP 27956 Score = 54.3 bits (129), Expect = 1e-06 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Query: 1797 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 +EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ + Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603 Query: 1857 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 I + G +L I D A YT A+N G T ++ VE +E E E E + Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659 Score = 54.3 bits (129), Expect = 1e-06 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447 G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W Sbjct: 11552 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 11606 Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507 F + ++ + + +H L + + D +L Sbjct: 11607 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 11656 Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565 V+E P F+ L D +E + L+C V VP + W +G+ I S G+ Sbjct: 11657 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 11714 Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 L I+ A +D G Y C G A VTV + + KP Sbjct: 11715 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 11756 Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684 L ++V G +++S P W G + S D + G +H L + Sbjct: 11757 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 11811 Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744 TG + +A N+ ++ A L V+E FI+ V C + Sbjct: 11812 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 11863 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782 + +P T WL+ + + D FE++++ ++V+K Sbjct: 11864 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 11899 Score = 54.3 bits (129), Expect = 1e-06 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158 F+ KL + G+ L + S P + W + L+ + I + +L I Sbjct: 16824 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 16879 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 KA D G Y V +N G + CQV V D P PPV Sbjct: 16880 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 16921 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 D K P I +K G+ V + + + TC K K + Sbjct: 16922 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 16977 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 + +++ ++EN Y + S +A+ V D PD P T Sbjct: 16978 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17022 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395 D S ++W +DGG + +Y +E ++ +K W + T F V DLL Sbjct: 17023 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 17077 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448 +Y+FRV A N G +PS S+ + +P V D VD Sbjct: 17078 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 17130 Score = 54.3 bits (129), Expect = 1e-06 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QL PV++K L PP F V G+ + GRP Sbjct: 22133 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 22175 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242 P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A Sbjct: 22176 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229 Score = 54.3 bits (129), Expect = 1e-06 Identities = 26/77 (33%), Positives = 44/77 (57%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300 Query: 232 TCLVVNGSGKASMSAEL 248 V N G+ + S E+ Sbjct: 23301 GITVANVVGQKTASIEI 23317 Score = 54.3 bits (129), Expect = 1e-06 Identities = 25/72 (34%), Positives = 40/72 (55%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382 Query: 232 TCLVVNGSGKAS 243 T N +G A+ Sbjct: 24383 TVTATNSAGTAT 24394 Score = 54.3 bits (129), Expect = 1e-06 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1865 P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 31748 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I+ V DDDA+YT A N GE +C A+L V Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782 Score = 53.9 bits (128), Expect = 1e-06 Identities = 51/230 (22%), Positives = 81/230 (35%), Gaps = 35/230 (15%) Query: 22 SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL 81 +R++ + L P+F + + +G+ E V G + W ++ Q I++ ++ Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723 Query: 82 DCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141 F L I + D G YTC ATN +G Q + LTV+ Sbjct: 4724 SFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------- 4766 Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201 PP F K V + + G + W K N L Sbjct: 4767 ------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL 4808 Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 A SV + + LE+ D G Y C + N G A+ A L ++ Sbjct: 4809 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858 Score = 53.9 bits (128), Expect = 1e-06 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 23011 Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260 T + N SG + SA ++++ LD+ + Sbjct: 23012 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 23069 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311 V + +AT VTN K+D L+ A P + P A Sbjct: 23070 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 23129 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363 PQPP + ++ + + T S I +Q + R L Sbjct: 23130 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 23188 Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411 + + GEE K + PR P + ++D+V + Sbjct: 23189 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 23229 Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471 P + S V+ Q +K +SG PKP + W +G P+ +Q I V + Sbjct: 23230 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 23286 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499 L + + D G Y T +N GQ + S Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTAS 23314 Score = 53.9 bits (128), Expect = 1e-06 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E A E KP ++D V S A+F K G P P +W KD ++I + +++ Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908 D+ G L I D YTC NS G + + +L ++ +++ E + Sbjct: 32901 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 32950 Score = 53.5 bits (127), Expect = 2e-06 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 PYF+K + +EV++ ++ G P E+ WFKD+ +R R ++ + +D SL Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQ 4451 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897 I D +Y C+ N +G + C+A + Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARV 4480 Score = 53.5 bits (127), Expect = 2e-06 Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%) Query: 1797 LEAVAEEKPHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 1855 LE AE + +P F+K I+++ V E +A F+C++ + D V W+K + ES+ + Sbjct: 8821 LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKY 8879 Query: 1856 QIDYDEDGNCS-LIISDVCGDDDAKYTCKA-VNSLGEATCTAELIVETME 1903 ++ DG C + I +V DD+ Y+ A + GEA TAEL + T E Sbjct: 8880 --NFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKE 8927 Score = 53.1 bits (126), Expect = 2e-06 Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 2/93 (2%) Query: 1809 PYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 P F K + ++V+ G ++R +CKI G P+ VVWF+++ + S +++ + D + Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDSVAVI 5481 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 ++++ +D + C+A N G +C+ ++IV+ Sbjct: 5482 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514 Score = 53.1 bits (126), Expect = 2e-06 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R GRP P++TW + + +V + + L I +++D G Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 24091 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289 Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D Sbjct: 24092 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 24143 Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328 AK KN +R + AN + + S K+E+ + Sbjct: 24144 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 24202 Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375 P + P L +TS+S+ + R G V + P G E K Sbjct: 24203 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 24261 Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423 GL S KA N + +P+ + + P + + Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 24321 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 ++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 24380 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 Y+ TA+N+ G + + ++ V V P F V D VI Sbjct: 24381 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 24424 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/82 (29%), Positives = 41/82 (50%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027 Query: 230 VYTCLVVNGSGKASMSAELSIQ 251 VYT N SG A ++ +Q Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQ 28049 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + + Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +++ +D+ YTC A N +GE +++L+++ Sbjct: 30593 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 30623 Score = 52.8 bits (125), Expect = 3e-06 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 +G A + CK+ G P ++ WF +D+ I+ES ++ + E L ++DV +D +Y Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYM 4371 Query: 1882 CKAVNSLGEATCTAELIVE 1900 C+A N G C++ +IV+ Sbjct: 4372 CEAQNEAGSDHCSSIVIVK 4390 Score = 52.8 bits (125), Expect = 3e-06 Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 4/113 (3%) Query: 1788 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 S E S + VA ++P P F K I + V S+A F + G P + W KDDQ Sbjct: 5030 SNEGGSCSCSTRVALKEP---PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 5086 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + E + I + D +L I V +YTC+A N G C A L+V+ Sbjct: 5087 ILDEDDNVYISF-VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138 Score = 52.8 bits (125), Expect = 3e-06 Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 48/235 (20%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P F K V +A G+ +C V+ P I W + + ++ ++ + ++++ Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTV 7271 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 K D G Y C A N AG+ CS Q+ V + Sbjct: 7272 LKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE---------------------------- 7303 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRK 1276 PP+ I+ E + V+ E K+ G+ I W K Sbjct: 7304 -------------------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDET 7344 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +IQES ++ ++ + L + E G YT N GS + +L V + P Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 7399 Score = 52.8 bits (125), Expect = 3e-06 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 PT + + V G V + + ++G PPP W G++++ESE E Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734 L I+E DTG YT E N G T V+ + +P T P I + S+T S Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 29855 Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790 G + L + WL +++ + T F L + + + + G Sbjct: 29856 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 29915 Query: 791 QYEILLKNRVGECSCQVSL 809 Y L++ V EC + + Sbjct: 29916 SY---LQSEVIECRSSIRI 29931 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90 AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127 LVI +D G+YT N G + L E + Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177 Score = 52.4 bits (124), Expect = 4e-06 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F KT+ ++V G+ A C++ G E+ WFKD + IR S+ +++ + + L Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL-FSQKSLVCLE 3889 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTA 1895 I D +Y C N +G+ C A Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMA 3916 Score = 52.4 bits (124), Expect = 4e-06 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 1781 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1840 ++A+ + D Q + +A++ + P F V+ G + D G P P V Sbjct: 22121 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 22179 Query: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV Sbjct: 22180 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237 Score = 52.4 bits (124), Expect = 4e-06 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%) Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280 K P TP PP+ P + SV L K G +T +++ ++ + Sbjct: 30315 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 30374 Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332 H K + + +T L E+ + ++ +N +G S + + VV DKP Sbjct: 30375 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 30432 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390 P S I S+TL W DGG + Y +E S + WK+ + F Sbjct: 30433 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 30491 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438 + LL EY+FRV A N G S P S +++LT+ GE P K+ +V+ Sbjct: 30492 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 30543 Score = 52.4 bits (124), Expect = 4e-06 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++ Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 30987 Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 ++ + T D T Y A+N G +S + +L+VE A + + P + + G+ Sbjct: 30988 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 31046 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587 ++ G P P ITW GQ + + V P +D G Y A+N Sbjct: 31047 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 31105 Query: 588 ALG 590 G Sbjct: 31106 RFG 31108 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G Sbjct: 31578 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 31637 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264 Y C VVN G+ S AEL ++G+ + R T Sbjct: 31638 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 31672 Score = 52.0 bits (123), Expect = 6e-06 Identities = 54/233 (23%), Positives = 82/233 (35%), Gaps = 48/233 (20%) Query: 1100 FKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158 F +KL+ + + G L C+V+ PP I W N + +K + +S S + + Sbjct: 4301 FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 ED G Y C A+N+AG CS V V ++P Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY-------------------------- 4394 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 T + KP +V V L +V GT P TW K + Sbjct: 4395 -FTKEFKPI--------------------EVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 4433 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 + K ++ L IL G Y V N++GS +T+ + P Sbjct: 4434 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 4486 Score = 52.0 bits (123), Expect = 6e-06 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%) Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164 ++ H+ G L L + P + W + T I ++ GS + I A ED Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 17283 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 G+Y +N AG S +V V D P P+ + +S K Sbjct: 17284 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 17331 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P G SV V + W ++ H Sbjct: 17332 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 17369 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341 +E L +AA EN+ G + DP P G P Sbjct: 17370 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 17417 Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399 D+ + ++L W DGGS + Y +E + + W + T + V L Sbjct: 17418 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 17477 Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 Y+FRV+A N+ G P + EK P E++V Sbjct: 17478 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 17514 Score = 52.0 bits (123), Expect = 6e-06 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 28026 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145 G YT EA N SG+ + +++ V+ + K +G + G++ + Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070 Score = 51.6 bits (122), Expect = 7e-06 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%) Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469 ++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++ Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158 Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505 + L + +A DSGTYS A+N+ G+ + + L V+ Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 51.6 bits (122), Expect = 7e-06 Identities = 51/244 (20%), Positives = 83/244 (34%), Gaps = 55/244 (22%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSV 1155 AP F + L++V L C+++ P + W +GK + + ++ I EG+ S+ Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT-ASL 4170 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215 I + D G + C A N G + S + V + Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204 Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 PP + P + V G +V L G+ P+T W K Sbjct: 4205 ---------------------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 4243 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVD 1329 K++ + S L + + G YT V N G + NL T V+ Sbjct: 4244 KELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVE 4303 Query: 1330 KPDP 1333 K +P Sbjct: 4304 KLEP 4307 Score = 51.6 bits (122), Expect = 7e-06 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 1816 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875 + ++V E +C + G P+ +V W KD + I SR+F + + E+ S I V Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF-ENNVASFRIQSVMKQ 5206 Query: 1876 DDAKYTCKAVNSLGEATCTAELIV 1899 D +YT K N G ++C A L V Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRV 5230 Score = 51.6 bits (122), Expect = 7e-06 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327 W K K + + H KV G + + EN G + Sbjct: 26716 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 26764 Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +D +PP +DI +S++LSW ++DGGS + Y +E D + W + Sbjct: 26765 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 26823 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417 T F + L + +Y+FRV A N G+ S PS+ Sbjct: 26824 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 26856 Score = 51.2 bits (121), Expect = 9e-06 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 V P F + ++D+ + G++ +C++ G V WF+D I Q + E+ C+ Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCT 6797 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L +S + D YTC A N G C+A L V+ Sbjct: 6798 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831 Score = 51.2 bits (121), Expect = 9e-06 Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1867 P F K + D+ V G + IEG VVWFKD + +RES + I Y E+ +L Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-IATL 7550 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 S V + KYTC+ N G C A L V Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSV 7582 Score = 51.2 bits (121), Expect = 9e-06 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385 + P PP P +D S+++ L W +++GG + Y ++ W + Sbjct: 15000 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 15057 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + V+++ +YK RV A+N G P E++ TV E E P E++VS Sbjct: 15058 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 15109 Score = 50.8 bits (120), Expect = 1e-05 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 V P F++ +++ V G++ +CK+ G V WF + I +Q + D C+ Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCT 5856 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L ++ + D YTC A N G C A L V+ Sbjct: 5857 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ 5890 Score = 50.8 bits (120), Expect = 1e-05 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%) Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183 PP T+ W + K L + + S ++I + D G Y +N G+ + S Sbjct: 27299 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 27358 Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238 V V D PA+ + SR + L PP++ S + ++K+ A K Sbjct: 27359 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 27410 Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298 TW + + ++ SE Sbjct: 27411 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 27436 Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356 + +L EN++G + V + PA S D +S+ LSW Sbjct: 27437 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 27487 Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 +DGGS + Y +E +TW ++ V L +FRV A N G S+P Sbjct: 27488 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 27547 Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439 + TV E P EV++SD Sbjct: 27548 TIGPI-TVKELIITP--EVDLSD 27567 Score = 50.8 bits (120), Expect = 1e-05 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%) Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343 SE K+T L E+ + ++ EN G A L +P P G P +D Sbjct: 28208 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 28265 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401 ++++L W +DGG + Y IE+ + W ++ C T + V DL EYK Sbjct: 28266 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 28325 Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 FRV AIN G + + + ++ P+ +++ + Sbjct: 28326 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 28362 Score = 50.4 bits (119), Expect = 2e-05 Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F K + DL + G + G V W K + IRE ++ + +G LI Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 3982 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I DV KYTC A N G T ELIV+ Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4014 Score = 50.4 bits (119), Expect = 2e-05 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%) Query: 1793 SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 1852 S A L A + P P+F++ ++D+ G F+C+I G +V W+KD +++ Sbjct: 7103 SSAVLVIKARKLP---PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDD 7159 Query: 1853 RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 + Q + + +L I +Y C A N LG A+ +A+LI+ E Sbjct: 7160 ANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209 Score = 50.1 bits (118), Expect = 2e-05 Identities = 55/281 (19%), Positives = 99/281 (35%), Gaps = 50/281 (17%) Query: 1041 AKPAETLKPMGNAKPD--ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAP 1098 AK ++P GN K EN + + ++ K C + D+ P Sbjct: 7246 AKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305 Query: 1099 AFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 F +KL+ + + + +C++ P ++W + ++ + +S S+ + + Sbjct: 7306 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 7365 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ED G Y C A N AG A S + V + PP+ Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE---------------------PPIF--- 7401 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +KKP P K G V L ++ GT P +W K +++ Sbjct: 7402 -----RKKPHPIETLK------------------GADVHLECELQGTPPFHVSWYKDKRE 7438 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGS 1318 ++ + K+ + + + IL G Y N +GS Sbjct: 7439 LRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 7479 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777 G P + + VT LG++ +SC I G P P + W R GK L + + +++ + Sbjct: 30530 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 30588 Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 TL + + G Y + N VGE L+LQ Sbjct: 30589 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623 Score = 49.7 bits (117), Expect = 3e-05 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 V P+F +++ G + F C + G ++ W KD++ IR ++++ E+ + Sbjct: 7210 VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN-TAT 7268 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L + V D +YTC A N G+ +C+A+L V+ Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302 Score = 49.7 bits (117), Expect = 3e-05 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%) Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 S P E + E P F L + VK G +TG+P+P++TW K ++ L+ Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 13732 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252 R+++ + I + D G Y VN G+A+ E+++ Sbjct: 13733 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 13792 Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 D N S + D ++TN + + DS Sbjct: 13793 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 13827 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P PP G P S+ +SW +GGS + Y +E + + W ++ Sbjct: 15599 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 15657 Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439 + FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D Sbjct: 15658 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 15715 Score = 49.7 bits (117), Expect = 3e-05 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L V PP I W+ L+ + + + E D G Y Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 19767 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G+ E + V V D P PPV T + + P Sbjct: 19768 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 19809 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P II + ++ + K T C+ FR V N E Sbjct: 19810 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 19852 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348 G + + EN+ G V P G +RS SS Sbjct: 19853 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 19900 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408 ++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N Sbjct: 19901 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 19959 Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 G P SE+T V +D+V D D K Sbjct: 19960 ENGEGTP---SEITVVA------RDDVVAPDLDLK 19985 Score = 49.7 bits (117), Expect = 3e-05 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+ Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 23296 Query: 789 AGQYEILLKNRVGECSCQVSLM 810 GQY I + N VG+ + + ++ Sbjct: 23297 GGQYGITVANVVGQKTASIEIV 23318 Score = 49.7 bits (117), Expect = 3e-05 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G Sbjct: 25117 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 25174 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277 Y + N SG S +A ++++ LDS + +RE K + D ++TN Sbjct: 25175 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 25232 Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330 I ++ + A + NC+ Q G S + + + E+ + Sbjct: 25233 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 25292 Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383 + P P + T +T A ++ E + G V + K + T Sbjct: 25293 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 25352 Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431 GL G + V AA R P E KP + VK + + Sbjct: 25353 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 25412 Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491 K G P+ V W +G + ++ + V L + +A D GTY SN Sbjct: 25413 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 25471 Query: 492 AQGQLSCSWTLQV 504 + G ++ T+ V Sbjct: 25472 SAGSITVPITIIV 25484 Score = 49.3 bits (116), Expect = 4e-05 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F K I + G A F ++G V W KD I E + ++ + E+ SL Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 4544 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +S + D KY C+A N G C+A L V+ Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576 Score = 49.3 bits (116), Expect = 4e-05 Identities = 24/81 (29%), Positives = 40/81 (49%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 19364 Query: 230 VYTCLVVNGSGKASMSAELSI 250 YT N SG S + +L + Sbjct: 19365 DYTITAENSSGSKSATIKLKV 19385 Score = 48.9 bits (115), Expect = 5e-05 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%) Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190 W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472 Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250 P PP S+ + +K TPP I + +++ Sbjct: 20473 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 20512 Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310 E+ L W + IQ H+ + + G++ + H G Sbjct: 20513 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 20553 Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 G + +VD+ P P P S++ ++ T+SW DGGS + Y + Sbjct: 20554 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 20608 Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426 E + + W + V L Y+FRV A N G PS+ S+ + + Sbjct: 20609 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 20668 Query: 1427 K--PEEPKDEVEVSDDDEK 1443 P P V+D +K Sbjct: 20669 AAYPPGPPSNPHVTDTTKK 20687 Score = 48.5 bits (114), Expect = 6e-05 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%) Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62 I++T++++ P S P+T A +PPR L +K G + V G P P Sbjct: 19267 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 19325 Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++ Sbjct: 19326 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 19382 Query: 121 LTV 123 L V Sbjct: 19383 LKV 19385 Score = 48.5 bits (114), Expect = 6e-05 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%) Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 + +D PP P +D +S++L+W +GGS V Y IE+ W + Sbjct: 30024 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 30081 Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 C +T +++ H EY+FRV A N G EP++ V E E P E++ Sbjct: 30082 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 30139 Score = 48.1 bits (113), Expect = 8e-05 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566 + + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367 Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 LHI++ +D G YT A N+ G + + V V EK Sbjct: 24368 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 24404 Score = 48.1 bits (113), Expect = 8e-05 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QLG PV+++ +E +PS+ E P F T VK + + GRP Sbjct: 25380 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 25422 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ + Sbjct: 25423 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 25480 Query: 249 SIQGLD 254 +I LD Sbjct: 25481 TIIVLD 25486 Score = 48.1 bits (113), Expect = 8e-05 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%) Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163 C TN ELT + + + V ++ D S P+ T P I + PP+ Sbjct: 25734 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 25789 Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 + +VVK G++ + + I GRP P ++W K + ++ AR + + +L + Sbjct: 25790 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 25849 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + D G Y + N +G S++ + Sbjct: 25850 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879 Score = 48.1 bits (113), Expect = 8e-05 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%) Query: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810 AV + + S M S + KS L++ + + ++ A LE + E+ Sbjct: 32495 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 32554 Query: 1811 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 T+ R + V EG +ARF C +G P P V W + Q + S Q+ + Sbjct: 32555 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 32613 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + IS V D+ Y+ NS G+ L ++ Sbjct: 32614 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651 Score = 47.8 bits (112), Expect = 1e-04 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1859 +++ KP+F K + L + A F+C++ DP +V W D + + + ++ Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754 Query: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +E G CSL D TC+A N G +A LIV+ Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795 Score = 47.8 bits (112), Expect = 1e-04 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F K LEV+ G F I G P +V WF+ + + + I Y ED L Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELE 5951 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + ++ +YTC N+ G+A+CT L V+ Sbjct: 5952 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983 Score = 47.8 bits (112), Expect = 1e-04 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%) Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322 G P+T ++ ++++ KV + + T+ Q + + NK G + Sbjct: 13515 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573 Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376 VN+ T PDPP D ++S+ L+W DGGS ++ Y +E + Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 13632 Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 W T V L Y +RV+A+N G S+PS+ +E + E P+ + Sbjct: 13633 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 13692 Query: 1436 EV 1437 +V Sbjct: 13693 DV 13694 Score = 47.8 bits (112), Expect = 1e-04 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%) Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478 K ++ + G P P+ +W +G + ++G ++ EDA S + + + + Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882 Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531 +G YS TA N GQ + + ++V + L V ++ + +G D Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 15941 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 ++G + + T ++G+ C G + D L E + AEN G Sbjct: 15942 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 15992 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 V ++ ++R P+ P P +K+ G TV +S PP Sbjct: 15993 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 16035 Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 + W G + + + ++ + ++++ + +A Sbjct: 16036 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 16094 Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756 N+AG + A + + P I + G +V I I G PFPT+ W + Sbjct: 16095 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 16154 Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 D K H L +D TLV+ + + G Y I N +G S ++ L Sbjct: 16155 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 16211 Score = 47.8 bits (112), Expect = 1e-04 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%) Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630 P D + +A NA+G +S S+ S ++ V P P + GL Sbjct: 27920 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 27969 Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690 + G + + V G P P V W +G EI++ + SL +++ + Sbjct: 27970 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 28026 Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714 G YT EA N++G + + + VQ+ Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQD 28050 Score = 47.4 bits (111), Expect = 1e-04 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 ++ + P F++ ++D+E G C++ G +V W++D +R+ + Q + D Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VD 6227 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897 +L I +Y+C A N LG A+ +A L Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262 Score = 47.4 bits (111), Expect = 1e-04 Identities = 47/244 (19%), Positives = 83/244 (34%), Gaps = 35/244 (14%) Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85 S+ E P F+ + G + V G+ V W ++ + I Sbjct: 6544 SVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFI 6603 Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145 +L + + + GKY C+ N +G R+ + LTV Sbjct: 6604 DNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE-------------------- 6643 Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205 P + K + V G C +TG P+ W K L + Sbjct: 6644 --------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADS 6689 Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 + ++ N + L+I D G+Y+ V N GK++ + + + SF+R+ K Sbjct: 6690 KHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD-RIVPPSFIRKLK 6748 Query: 266 ATNS 269 N+ Sbjct: 6749 DVNA 6752 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +++P PP +SD SS+ L W DGGS + Y IE + W + Sbjct: 13289 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 13347 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 ++ V L ++Y +RV A N G S+PS+ T + EP ++ D Sbjct: 13348 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 13402 Score = 47.4 bits (111), Expect = 1e-04 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632 +P++ T T L E A Q A V+ S S+ + +A + P + + S L Sbjct: 19246 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 19305 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689 V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D Sbjct: 19306 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 19362 Query: 690 TGTYTCEAWNSAG 702 +G YT A NS+G Sbjct: 19363 SGDYTITAENSSG 19375 Score = 47.4 bits (111), Expect = 1e-04 Identities = 25/82 (30%), Positives = 36/82 (43%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 + KE R I G+P P V+W KG PL RVSV L ++ + D G Sbjct: 19993 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 20052 Query: 231 YTCLVVNGSGKASMSAELSIQG 252 YT + N +G + + + G Sbjct: 20053 YTITLKNVAGTKEGTISIKVVG 20074 Score = 47.4 bits (111), Expect = 1e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 L I +++D GKYT ATN +G + + V Sbjct: 24368 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 NA S S + E P + + + L + G + R ++G P P V Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 27991 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+ Sbjct: 27992 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049 Score = 47.4 bits (111), Expect = 1e-04 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102 I+ G+ + V G PEP++ W + + + + L G R T VI D G Sbjct: 29059 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 29116 Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158 KYT N SG + V+V + V S G+ VS+ ++ +S P + I Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 29175 Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213 + T V+ EG+ S +T + +V + P P + +N Sbjct: 29176 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 29235 Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269 + G+ ++ G ++ ++ E+S +D + +R T+ Sbjct: 29236 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 29295 Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327 D R +VT+++ + C R + A NS+P S SC++ Sbjct: 29296 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 29338 Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376 P +AP+ V+ T SI+L + + +G + E+ A Sbjct: 29339 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 29396 Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420 R F +G + AA + ++G + + E +P Sbjct: 29397 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 29453 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479 ++ ++ +++ VSG P P + W +G + S + + S+ L ++ K Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 29509 Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G Sbjct: 29510 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 29565 Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590 G PV I + T + I + + L EN G Sbjct: 29566 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 29619 Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 S V V E +P+ P+K L+V+D ++ T+T ++ Sbjct: 29620 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 29655 Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705 P L++G + GT+ + + + P E T T E +R Sbjct: 29656 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 29710 Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752 Q V EP + + R ++ G+ V + IAG P P Sbjct: 29711 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 29770 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 W G L +++ V + V L +++ G+Y + LKN G S + +++ Sbjct: 29771 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 29829 Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 + A ++ EP + GG G ++ + RPGW Sbjct: 29830 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 29879 Score = 47.4 bits (111), Expect = 1e-04 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387 P PP G P + + W DGG+ + +Y ++ + + W + T Sbjct: 29240 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 29298 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 V L+ +Y+FRV A+N G SEPS+ S + E P Sbjct: 29299 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 29342 Score = 47.4 bits (111), Expect = 1e-04 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63 V + S S++ ++P +P E + + + I+ GA+ + V G P P Sbjct: 29420 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 29477 Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 +TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V Sbjct: 29478 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534 Score = 47.0 bits (110), Expect = 2e-04 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%) Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169 EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+ Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 31640 Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228 C ND G+ ++ V + + RR T+KK K Sbjct: 31641 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 31680 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285 T PP+ ++ GE+V +T TW K ++I+ ++ K Sbjct: 31681 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 31740 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334 E+ + +LTI + + YT++ NK G + LTV P P Sbjct: 31741 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 31800 Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 G +IR S + TL W DG +IEI + Sbjct: 31801 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 31851 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 + +++D LP+ +RV A N G++ ++ + K +E K + E +K+ Sbjct: 31852 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 31908 Query: 1445 PEVDYRTVTI 1454 + R I Sbjct: 31909 IDKTLRMAEI 31918 Score = 46.2 bits (108), Expect = 3e-04 Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Query: 1807 VKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1865 + P F+K + + +E EG++ + + ++ G V W+K++ I+ + + +I + ++ Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTL 8305 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L + +D YTCK N G A CT+ ++++ Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340 Score = 46.2 bits (108), Expect = 3e-04 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444 GLG D IP+E Q P E + E VK TV+F + G+P P Sbjct: 17489 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 17541 Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504 W +G+ ++ E V D S L + RD+G Y T SNA G + + L V Sbjct: 17542 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600 Score = 46.2 bits (108), Expect = 3e-04 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 LP KE + + + ++G P P V+W + P+ + R ++ T +L+++ Sbjct: 19987 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 20045 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125 + D GKYT N +G ++ T+ + V G Sbjct: 20046 QKSDAGKYTITLKNVAGTKEGTISIKVVG 20074 Score = 46.2 bits (108), Expect = 3e-04 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%) Query: 1768 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1822 S ++ + P+ P E++ E V + A + +K SK I L VVE Sbjct: 32681 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 32740 Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C Sbjct: 32741 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 32791 Query: 1883 K 1883 + Sbjct: 32792 E 32792 Score = 45.8 bits (107), Expect = 4e-04 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I + Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188 D G YK + G+ E +C ++V+ Sbjct: 2511 DEGPYKLI----VGRVETNCNLSVE 2531 Score = 45.8 bits (107), Expect = 4e-04 Identities = 53/238 (22%), Positives = 95/238 (39%), Gaps = 30/238 (12%) Query: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQH------PWLMKDTKNMEAKKLSKD 1734 D+ AF EIS + S N+ QC H P+ ++ ++ + ++ Sbjct: 4727 DNTAFLEISQ-LEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRV 4785 Query: 1735 RMKKYMARR-----KWQKTGN-----AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE 1784 ++K + KW K A R++ + + + + + + +G+ L+ Sbjct: 4786 QLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS-- 4843 Query: 1785 KLESEEDVSQAFLEAV--AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW 1842 DV A +A +E P + K L + G + F+C+I G P V W Sbjct: 4844 -----NDVGTATSKATLFVKEPPQ---FIKKPSPVLVLRNGQSTTFECQITGTPKIRVSW 4895 Query: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + D I + I + DG + IS ++ Y C+A N G A+C+ EL V+ Sbjct: 4896 YLDGNEITAIQKHGISF-IDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 4952 Score = 45.8 bits (107), Expect = 4e-04 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1867 P F K + D + G A +EG+ VVW KD + IRES + +I + D +L Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATL 6609 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + + KY C+ N G C+A L V Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641 Score = 45.8 bits (107), Expect = 4e-04 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%) Query: 1799 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1858 ++ ++P P F + + + V EG + C ++G + W K + I+ S Sbjct: 8336 SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS 8395 Query: 1859 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + G L + DV D Y CKA N G T +++ ++ Sbjct: 8396 F-ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436 Score = 45.8 bits (107), Expect = 4e-04 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864 PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I + Sbjct: 12372 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 12427 Query: 1865 CSLIISDVCGDDDAKYTCK 1883 L+I+ DD+A+Y+C+ Sbjct: 12428 RILVINKCLLDDEAEYSCE 12446 Score = 45.8 bits (107), Expect = 4e-04 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565 ++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G Sbjct: 27957 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 28013 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 L ++DA + G YT A+NA G V V + Sbjct: 28014 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 28050 Score = 45.4 bits (106), Expect = 5e-04 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++ Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + L+I D KYT A G TA+L VE Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143 Score = 45.4 bits (106), Expect = 5e-04 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F +T +EV+ G + F I G P +V WFK + + I ED L Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISL-EDFVTELE 6892 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + +V + Y+C N G A+CT L V+ Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924 Score = 45.4 bits (106), Expect = 5e-04 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%) Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169 RQ TV+ EG+ K V + G P ET+P E A +L G Sbjct: 15059 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 15113 Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + + G+ R +TGRP P W K L RV + L I + D G Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 15172 Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 Y N G +A L ++ + + + + D E+T I Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 15232 Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327 K++K+ + +E + + G + ++ + PP E D Sbjct: 15233 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 15292 Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381 P T+P+ ++T S+ITL EPR+ G + E++R P Sbjct: 15293 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 15348 Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423 PT + + D KA N +P+ Q D P + + + Sbjct: 15349 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 15408 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478 +VK + V +V+G+P P++ W T + + ++++ ++ S L + KA Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468 Query: 479 TRDSGTYSCTASNAQGQL 496 D GTY+ TASN G + Sbjct: 15469 REDKGTYTVTASNRLGSV 15486 Score = 45.4 bits (106), Expect = 5e-04 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%) Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567 +V P+FSS +V GQD ++ + G P P ITW +G P++ T + Sbjct: 23231 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 23286 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I++ +D G Y N +GQ + S + +K P P P+ Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 23333 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651 +S ++ +S NPP Sbjct: 23334 DVS----------AESITLSWNPP 23347 Score = 45.4 bits (106), Expect = 5e-04 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 + G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382 Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715 T A NSAG +V+ +++P Sbjct: 24383 TVTATNSAGTATENLSVIVLEKP 24405 Score = 45.1 bits (105), Expect = 7e-04 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +K G + E V G P P + W ++G+ + + + T +LV D G Sbjct: 21473 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 21531 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160 YT ATN G FAK + V G + V + + P Sbjct: 21532 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 21578 Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215 P K+ +V++ + R + + QVT LK L+ + RV K G+ Sbjct: 21579 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 21637 Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256 VL ++ D + C S S ++ D A Sbjct: 21638 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 21697 Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315 + +++ K T +D+R +V+ + E + + A + SP +P Sbjct: 21698 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 21757 Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366 PP + L++ + S A P+ S PE P A GL S Sbjct: 21758 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 21816 Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423 + + + GLG +V KA +R +P E + D+ K + Sbjct: 21817 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 21871 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481 ++ T++ + G P PEV W + E + ++ S Y L+ D Sbjct: 21872 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 21925 Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 SG Y T N+ G S ++V + L V EV + ++ D +++G + Sbjct: 21926 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 21985 Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593 V R + + C ++ D L E Y LAEN G + Sbjct: 21986 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 22034 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 A K S R P+ P K T +MD ++ +V +S P Sbjct: 22035 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 22073 Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 H+G + +G+ + + C E T T + + V Q + Sbjct: 22074 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 22129 Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 +P + P I+K + T G+ + + G P P V W +D L Sbjct: 22130 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 22188 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802 K T E+ L +K G Y + L N GE Sbjct: 22189 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 22228 Score = 45.1 bits (105), Expect = 7e-04 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%) Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284 P PP A P++ + +R E G I W+ K R I + Sbjct: 28837 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 28891 Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 KV E K+T L E+ Y L + +A + + D P G P +D+ Sbjct: 28892 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 28950 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398 S+++L W +YDGGS V Y IE + + + W + F V L Sbjct: 28951 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 29010 Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 Y+FRV A N G S+ S+ + T ++ PK E++ Sbjct: 29011 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 29049 Score = 44.7 bits (104), Expect = 9e-04 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%) Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 W+ +G+ I+ES F G L I +V D G YTC E + A L V+E Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210 Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775 + + VT GQ + +SC + + V W +DGK + + G Sbjct: 11211 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 11265 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810 + L + AG Y + ++N ECS V ++ Sbjct: 11266 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301 Score = 44.7 bits (104), Expect = 9e-04 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386 P P G P D+ S+++L W +DGGS + Y +E W T Sbjct: 19189 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 19248 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + L +Y+FR A S PS+ S+ T+ + P+ ++ V+ Sbjct: 19249 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 19300 Score = 44.3 bits (103), Expect = 0.001 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99 L +K G T +F +RG P P W +G I + + ++ FS L I Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 17576 Query: 100 DRGKYTCEATNGSGARQVTVELTV 123 D G+Y +N +G++ V V LTV Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTV 17600 Score = 44.3 bits (103), Expect = 0.001 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%) Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 +EK S + +PV A P F + V+ G + + V G P P V W + Sbjct: 22125 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 22184 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718 ++++ + E L I++ ED G Y + NSAGE + T V+ + +P Sbjct: 22185 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 22244 Query: 719 TQP 721 T P Sbjct: 22245 TGP 22247 Score = 43.9 bits (102), Expect = 0.002 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 + V G +CK+ G P+ V W+KD + + S+ + + + SL I V D Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 5771 Query: 1878 AKYTCKAVNSLGEATCTA 1895 YT + N++G+++CTA Sbjct: 5772 GTYTFQVQNNVGKSSCTA 5789 Score = 43.9 bits (102), Expect = 0.002 Identities = 54/235 (22%), Positives = 90/235 (38%), Gaps = 42/235 (17%) Query: 20 DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF 79 D S ++ + P F P + +G+ + + G P +V W ++ + + + +F Sbjct: 6445 DASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKF 6504 Query: 80 LLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPVVS 137 + T SL I + D G+Y C+ATN GS +V+ F K+L S Sbjct: 6505 KITSKHFDT-SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSD--TS 6561 Query: 138 KTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK- 196 +GD AVE R + G P V WLK Sbjct: 6562 TLIGD-----AVELRAIVEGFQP-----------------------------ISVVWLKD 6587 Query: 197 -GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 G V ++ S +S + + L++ + G Y C + N +G SA L++ Sbjct: 6588 RGEV-IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641 Score = 43.9 bits (102), Expect = 0.002 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 ++V G +C + G P+ WFKD + + ++I + + L I +V D Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 7653 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 Y+ + N +G+ +CTA L V Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQV 7675 Score = 43.9 bits (102), Expect = 0.002 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + ++V+ G+ F ++G P V WFK + + ED L Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELE 7833 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + DV +YTC N G+A+CT L ++ Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865 Score = 43.9 bits (102), Expect = 0.002 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V+V+ G R + GRP P+VTW K + + V + M L I +DD G Sbjct: 18616 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 18674 Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279 Y+ +VN +G+ ++ + + + S V +T +D +VT+ I Sbjct: 18675 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 18734 Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311 ++ + D A P P A++ Sbjct: 18735 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 18794 Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365 S+P PPR+ ++ + T P L+ K IT QP R V+ Sbjct: 18795 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 18854 Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413 G++ K R A + P G V +A + +P Sbjct: 18855 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 18899 Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 PK P+ +K + ++ V G P P W +G + V++ S L Sbjct: 18900 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 18957 Query: 474 LLKARTRDSGTYSCTASNAQG 494 + +DSG YS TA N+ G Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978 Score = 43.9 bits (102), Expect = 0.002 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L Sbjct: 18899 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 18957 Query: 220 IHGVNQDDVGVYTCLVVNGSG 240 I V + D G Y+ N SG Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978 Score = 43.5 bits (101), Expect = 0.002 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Query: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 KP+F K + ++ +C+++ V W KD Q + + ++I + ED +L Sbjct: 3643 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATL 3701 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 I D Y C A N G ++C+A + V Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%) Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 VK V ++ +SK S +V P R D P + F+ ++EG +++G P Sbjct: 16091 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 16144 Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 P +TW + N +P+ T + ++D T +LVI D G YT A N Sbjct: 16145 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 16200 Query: 111 GSGARQVTVELTVEG 125 G + L V G Sbjct: 16201 NLGTASKEMRLNVLG 16215 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 1810 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 + +KT++++EV E A F+C++ + P +W K+ I S F+I + LII Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 + +D A+YT N AT T I+ T + EE++ Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984 Score = 43.1 bits (100), Expect = 0.003 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1870 +EV EG+ KI+G P P + WFK +++ + YD D C+L+I Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 16184 Query: 1871 DVCGDDDAKYTCKAVNSLGEAT 1892 D YT AVN+LG A+ Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS 16206 Score = 43.1 bits (100), Expect = 0.003 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 Y N SG A SA +++ LD + K TN V KE IS E+ LD+ Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 18028 Score = 43.1 bits (100), Expect = 0.003 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V E K + P + + G R + + G P P W K + + S H + Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 18947 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + D + LII DV D Y+ A NS G T +++V Sbjct: 18948 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988 Score = 43.1 bits (100), Expect = 0.003 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1838 NA + SE S + A E P + P + TI V G + + D I G P P Sbjct: 22517 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 22573 Query: 1839 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 + W K DQ + + +I D SL + D D Y KA N GE + T + Sbjct: 22574 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 22632 Query: 1899 V 1899 V Sbjct: 22633 V 22633 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390 P PP S + S+TL W DGGS + Y IE + + W + Sbjct: 25983 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 26041 Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421 V+ L EY++RV A N G S PS+ S L Sbjct: 26042 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 26074 Score = 42.7 bits (99), Expect = 0.003 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%) Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150 +G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2319 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 +++++ ED+G Y V Sbjct: 2320 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2339 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 + G ++ +K KP P I+Q DQKV G+ V+L KV+ + + Sbjct: 2340 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2387 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2447 Query: 1331 PDP 1333 P Sbjct: 2448 ITP 2450 Score = 42.7 bits (99), Expect = 0.003 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Query: 1811 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1864 F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D Sbjct: 11117 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +I DV D +YTC E T TA+L+VE + Sbjct: 11175 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210 Score = 42.7 bits (99), Expect = 0.003 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%) Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167 + + TV G Q + V++K S P+ T P + PKF Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 23634 Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227 +VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D Sbjct: 23635 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 23692 Query: 228 VGVYTCLVVNGSGKASMSAELSI 250 G Y N +G S + + Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKV 23715 Score = 42.4 bits (98), Expect = 0.004 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%) Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107 +KS K +++ K + + +N + H G + + T+ A F++ ++D+ Sbjct: 3008 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3067 Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167 V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G Sbjct: 3068 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3126 Query: 1168 YKCVAKNDAGQAE 1180 Y VA + A+ Sbjct: 3127 YTVVAGGNVSTAK 3139 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 +K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 17287 Query: 232 TCLVVNGSGKASMSAELSI 250 + V N +G ++S ++ + Sbjct: 17288 SLTVENPAGSKTVSVKVLV 17306 Score = 42.4 bits (98), Expect = 0.004 Identities = 21/72 (29%), Positives = 34/72 (47%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++++ G R + GRP P++TW K NV L+ + + + L VN+ D G Sbjct: 19703 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 19762 Query: 230 VYTCLVVNGSGK 241 Y + N GK Sbjct: 19763 KYILTLENSCGK 19774 Score = 42.4 bits (98), Expect = 0.004 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + + V G P P V W +++++ +FE T L I E D+G Y Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139 Query: 697 AWNSAGEVRTQAVLTVQ 713 A N GEV V+T+Q Sbjct: 21140 ARNIVGEVGD--VITIQ 21154 Score = 42.4 bits (98), Expect = 0.004 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576 KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+ Sbjct: 22550 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 22609 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633 D G Y A+N G+ S VTV+ K R P P P+ + G++ K Sbjct: 22610 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 22656 Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656 + DG + V ++W Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVW 22684 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 +P VKP FS V G + + I G P P + W KD ++++ + D Sbjct: 23229 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 23283 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 +L I + DD +Y N +G+ T + E++ Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 23318 Score = 42.4 bits (98), Expect = 0.004 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795 + + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+ Sbjct: 25410 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 25468 Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 + N G + +++++ + P + SC+ + Sbjct: 25469 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 25504 Score = 42.0 bits (97), Expect = 0.006 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158 F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I Sbjct: 12287 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 12344 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 PED Y C DA + SC + V Sbjct: 12345 DCTPEDIKTYTC----DAKDFKTSCNLNV 12369 Score = 42.0 bits (97), Expect = 0.006 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E F N+ + E T K V P +V W++ + I GR+ + R Sbjct: 12459 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 12517 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 LVI H ED G Y C + +V V Sbjct: 12518 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 12548 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 E +F +K + + EG+ F C I+ P V W + + L+ + Sbjct: 12549 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 12598 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 V +VL + D+G Y +V G A +A L++ Sbjct: 12599 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 12636 Score = 42.0 bits (97), Expect = 0.006 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578 G+ + V G P+P+I W N I+ + EL I A+ ED Sbjct: 15413 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 15472 Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605 GTYT A N LG V + V V+++ S Sbjct: 15473 GTYTVTASNRLGSVFRNVHVEVYDRPS 15499 Score = 42.0 bits (97), Expect = 0.006 Identities = 26/93 (27%), Positives = 39/93 (41%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P+ + ++ + L V G+ V + G P P W +G+EI+ E + E Sbjct: 17508 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 17567 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 L I+ DTG Y N+AG LTV Sbjct: 17568 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600 Score = 42.0 bits (97), Expect = 0.006 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V G P P+V W G ++G +++ + +L + + DSG YS T N G+ Sbjct: 18630 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 18687 Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 + ++V L V +V + V +G V V R TW Sbjct: 18688 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 18745 Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609 + T E H+ + +P + + A N G V K S Sbjct: 18746 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 18793 Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666 + L S+P P + ++ +++T PP L +G + Sbjct: 18794 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 18835 Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716 E+ R T++S+ ++++ TG + A N+ G + V E Sbjct: 18836 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 18894 Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776 + P I P +T G+ + I + G P PT W + G+ + H V + + Sbjct: 18895 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 18953 Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820 L++K V +G Y + +N G + ++ +++ ++ P Sbjct: 18954 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 18997 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T G +V + + G P PTV W +DG L K ++ ++ TL L V + Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 19363 Query: 790 GQYEILLKNRVGECSCQVSL 809 G Y I +N G S + L Sbjct: 19364 GDYTITAENSSGSKSATIKL 19383 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 VV+ G R GRP P W K + L S R + + L + N++D G Sbjct: 28368 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 28425 Query: 231 YTCLVVNGSGKASMSAELSI 250 YT V N SG S++ + + Sbjct: 28426 YTLTVENNSGSKSITFTVKV 28445 Score = 42.0 bits (97), Expect = 0.006 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639 + LA+NA G +S + T + + EY AP K L G DL + GS Sbjct: 29014 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 29064 Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699 + + V G P P++IW E+ E + G + + I+ D+G YT N Sbjct: 29065 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 29124 Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721 ++G T+AV + + D P Sbjct: 29125 ASG---TKAVSVMVKVLDSPGP 29143 Score = 42.0 bits (97), Expect = 0.006 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 T D ++ P E + G+ V ++ G + G+P+P++ W KG+ Sbjct: 29036 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 29085 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255 L +VS+ I ++ D G YT V N SG ++S + + LDS Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 29140 Score = 41.6 bits (96), Expect = 0.008 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98 +N+ + E TA FE V + P + W +NG I +F + ++G L+I Sbjct: 2889 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2945 Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134 ED +YT N + +TV E+TV EG K L Sbjct: 2946 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 3005 Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168 V K+ GD F A + +++ E +F + Sbjct: 3006 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3065 Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 + V E + F C+++ P V W+K + LQ + R+ + ++ + L I D Sbjct: 3066 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124 Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 G YT + +G +A+L ++G D RS +E + Sbjct: 3125 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3157 Score = 41.6 bits (96), Expect = 0.008 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V + Q + CE++ + +V W +G V + G I L + A D+GT Sbjct: 11224 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 11281 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ T NA L CS ++V V + ++D V + C + P Sbjct: 11282 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 11335 Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 I W + +P + L I++A+PED Y E A +T Sbjct: 11336 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 11391 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 + E R+ E L P+ D+ + + + ++S P W Sbjct: 11392 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 11432 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 G ++ S + G + L + +V + G +A N+ T A+LTV+E Sbjct: 11433 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 11484 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 + F + VT + C + + V W + G + K + F+++ + L Sbjct: 11485 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 11541 Query: 780 VLKKVQPWHAGQY 792 V+ Q G Y Sbjct: 11542 VINDSQFDDEGVY 11554 Score = 41.6 bits (96), Expect = 0.008 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 12522 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1913 + +D Y C+ +S + EL E + + + EGE+ E Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570 Score = 41.6 bits (96), Expect = 0.008 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%) Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64 A+ ISK S S P + + E P + P+ + + G T + E V G P P + Sbjct: 23600 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 23657 Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 W R + I R C I+ T L++ D G+Y A+N +G++ V + Sbjct: 23658 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 23713 Query: 122 TV 123 V Sbjct: 23714 KV 23715 Score = 41.6 bits (96), Expect = 0.008 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++VK G + GRP P V W K + L+ A V ++ L I N++D G Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 26253 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 YT + N AS++ L ++ LD+ T T DV KE Sbjct: 26254 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 26292 Score = 41.6 bits (96), Expect = 0.008 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 28028 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 Y+ A NA G ++V+ V P Sbjct: 28029 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 28058 Score = 41.6 bits (96), Expect = 0.008 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1864 + P D+ + EG C G P PEV W + I +E F I+ + D Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 33385 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +LII DV D YT N G + T + + ++ Sbjct: 33386 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423 Score = 41.2 bits (95), Expect = 0.010 Identities = 24/96 (25%), Positives = 43/96 (44%) Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217 +C P + ++V EG+ P P V+W K ++ S R+++ + Sbjct: 14384 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 14443 Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253 LE+ + D G+YT + N G A+ S + + GL Sbjct: 14444 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479 Score = 41.2 bits (95), Expect = 0.010 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570 P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L + Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 14446 Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600 ++ D G YT EN LG + S V V Sbjct: 14447 PKSVRADAGIYTITLENKLGSATASINVKV 14476 Score = 41.2 bits (95), Expect = 0.010 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454 VSK + P + QR P + K + EV+E V ++ G+P P + WF P Sbjct: 16099 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 16155 Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506 ++ + V D + L C L ++R D+G Y+ TA N G S L V Sbjct: 16156 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 16215 Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557 V P F SV D + +G + + R TW+ ++ +P Sbjct: 16216 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 16271 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 C + +L L + +A+N G + + + ++ + +P AP Sbjct: 16272 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 16320 Query: 618 SKPT 621 KPT Sbjct: 16321 DKPT 16324 Score = 41.2 bits (95), Expect = 0.010 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K I L V G+ RF I G P P W D I+ H+ ++ D + L I + Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 17573 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D +Y N+ G T L V Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTV 17600 Score = 41.2 bits (95), Expect = 0.010 Identities = 23/80 (28%), Positives = 36/80 (45%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G++ ++ I G P P V W +DGK L + E+ TLV+K Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776 Query: 790 GQYEILLKNRVGECSCQVSL 809 GQY + L N G S +++ Sbjct: 24777 GQYILKLSNVGGTKSIPITV 24796 Score = 41.2 bits (95), Expect = 0.010 Identities = 26/85 (30%), Positives = 34/85 (40%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L+L V P IIWT K L + + L G + I+ D G Sbjct: 29057 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 29116 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y KN +G S V V D+P Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDSP 29141 Score = 40.8 bits (94), Expect = 0.013 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F K + D V GS + G P V W KD+ I +S I E I+ Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 +D A+Y+C N G+ C E +V +E Sbjct: 6989 STI-EDYAQYSCLIENEAGQDIC--EALVSVLE 7018 Score = 40.8 bits (94), Expect = 0.013 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 +++ + E + ++ I + DTGTY EA N G R AV+ V Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 13778 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D Sbjct: 13695 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 13753 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y +AVN G AT E+ V Sbjct: 13754 KRSDTGTYIIEAVNVCGRATAVVEVNV 13780 Score = 40.8 bits (94), Expect = 0.013 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389 P PP + I ++ L W DGGS + +Y +E D K W+ + T + T Sbjct: 14084 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 14142 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414 V L Y FRV A N G S+ Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSD 14167 Score = 40.8 bits (94), Expect = 0.013 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P IL P + IK G + E V G P P W + + + + + L+ Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 18957 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I V +D G Y+ A N SG +++ V Sbjct: 18958 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988 Score = 40.8 bits (94), Expect = 0.013 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%) Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542 ++ +A N +G +S L V +A + + P+F + V+ G+D + G P Sbjct: 22118 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 22176 Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V Sbjct: 22177 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 22236 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624 V +K P PT P+ Sbjct: 22237 VLDK-------------PGPPTGPV 22248 Score = 40.8 bits (94), Expect = 0.013 Identities = 20/81 (24%), Positives = 39/81 (48%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G Sbjct: 22553 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 22612 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y N +G+ S++ + + Sbjct: 22613 NYILKAKNVAGERSVTVNVKV 22633 Score = 40.8 bits (94), Expect = 0.013 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 ++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+ Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 23299 Query: 104 YTCEATNGSGARQVTVEL 121 Y N G + ++E+ Sbjct: 23300 YGITVANVVGQKTASIEI 23317 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 ++P + G + + + G P P + W KD + ++++ ++ + + Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 24368 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + DD KYT A NS G AT +IV Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/74 (31%), Positives = 33/74 (44%) Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 Q+ + V G P V W +G ++E+ + T SL I+E ED GTY Sbjct: 25411 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 25470 Query: 699 NSAGEVRTQAVLTV 712 NSAG + + V Sbjct: 25471 NSAGSITVPITIIV 25484 Score = 40.8 bits (94), Expect = 0.013 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757 +V EP + T P + PR + G+ + I+ IAG P P + W +D Sbjct: 25767 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 25826 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808 G + ++ E++ ++ L +K GQY + LKN G S V+ Sbjct: 25827 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 25876 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 12344 Query: 1871 DVCGDDDAKYTCKA 1884 D +D YTC A Sbjct: 12345 DCTPEDIKTYTCDA 12358 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + ++ G T + RV+G PEP +TW + G+ + R L + L I D Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 17976 Query: 102 GKYTCEATNGSGARQ 116 GKY A N SG Q Sbjct: 17977 GKYIISAKNSSGHAQ 17991 Score = 40.4 bits (93), Expect = 0.017 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 17978 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y +A N+ G S + V + L V V ++ + + G + V Sbjct: 17979 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 18038 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596 +P Q S + V + I+ + L + + AEN +G Sbjct: 18039 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 18082 Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650 T+ K +L + P +P P +L + D + + ++ G Sbjct: 18083 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 18130 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705 P + H ++ S+D+ +G+ + + + + N GE V+ Sbjct: 18131 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 18188 Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763 T+ V+ + D +P K V T G ++ + + G PFP V W +D A Sbjct: 18189 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 18245 Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 + ++ D L K + G+Y + N G Sbjct: 18246 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 18283 Score = 40.4 bits (93), Expect = 0.017 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VK V V G P P V+W +GT ++ EG I++ L L +DSG Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 19365 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y+ TA N+ G S + L+V Sbjct: 19366 YTITAENSSGSKSATIKLKV 19385 Score = 40.4 bits (93), Expect = 0.017 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%) Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL Sbjct: 23608 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 23661 Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605 + I+ + + CE A L ++DA+ D G Y A N G S V V ++ Sbjct: 23662 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 23718 Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633 P P P+ + G++ K Sbjct: 23719 -----------PGPPEGPVQVTGVTSEK 23735 Score = 40.0 bits (92), Expect = 0.022 Identities = 46/201 (22%), Positives = 72/201 (35%), Gaps = 29/201 (14%) Query: 1742 RRKWQKTGNAVRAIGRLS-----SMAMISGLSGRKSSTGS----PTSPLNAEKLESEEDV 1792 R +W K G ++ R S A++ K+ +G ++ ++ +S+ + Sbjct: 8376 RIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 8435 Query: 1793 SQAFLEAVAEEKPHV--KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1850 A A +K V + +F + + VVE + A F K+ G P P V W K Sbjct: 8436 KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 8495 Query: 1851 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE---- 1906 + + L I D D Y C A N GE L V+ ++ E Sbjct: 8496 NQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEG 8555 Query: 1907 --------------GEGEEEE 1913 G GEEEE Sbjct: 8556 DLRAMLKKTPILKKGAGEEEE 8576 Score = 40.0 bits (92), Expect = 0.022 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 21/180 (11%) Query: 7 VASSHISKTSLSVDPSRVDSMPLTEAPA------FILPPRNLCIKEGATAKFEGRVRGYP 60 VA S +K+ +++ + P T+ A F+ P+++ + E TA F +V G P Sbjct: 8423 VAGSDTTKSKVTIKDKPAVA-PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481 Query: 61 EPQVTWHR-NGQPITSGGR-FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118 P V W + + + GGR F+ G L I + D G Y C A N G + Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEA--KLEIRDTTKTDSGLYRCVAFNEHGEIESN 8539 Query: 119 VELTV---------EGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG 168 V L V EG L + P++ K G+ +E ++ + K+A G Sbjct: 8540 VNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYG 8599 Score = 40.0 bits (92), Expect = 0.022 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%) Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72 DP+ V L E P IL R IK G T + ++G P P+VTW + + Sbjct: 17199 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 17258 Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + R +D G+ + +A H ED G Y+ N +G++ V+V++ V Sbjct: 17259 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 17306 Score = 40.0 bits (92), Expect = 0.022 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482 VK T++ V G P PEVAW + T + R +++ A S L KA+ D Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 18271 Query: 483 GTYSCTASNAQGQLSCSWTLQV 504 G Y TA+N G T+ V Sbjct: 18272 GKYVVTATNTAGSFVAYATVNV 18293 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%) Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656 V V+EK S +P VA P S V G + + V +SG P P + W Sbjct: 23204 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 23263 Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715 +G ++++ + +L I+E +D G Y N G+ + ++T+ +P Sbjct: 23264 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 23323 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575 KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D + Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y N G S V V ++ P P P+ + G++ Sbjct: 24774 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 24815 Score = 40.0 bits (92), Expect = 0.022 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%) Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 Q+ V+ +++ G P P W P +++ L + Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 28421 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y+ T N G S ++T++V + +V ++++ D +++G + Sbjct: 28422 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 28481 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 V R +W Q C + +++ LAE Sbjct: 28482 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 28521 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 SA V+E E P+ ++ AP L V+D S+ + + Sbjct: 28522 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 28565 Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700 WL H+G Q+ DF E T Q + ++ + + + +A N Sbjct: 28566 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 28623 Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 AG + + ++EP + T + +T G I I+G P P V W Sbjct: 28624 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 28683 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 + L K+T + +D TL +K +G+Y + L+N G + V++++ Sbjct: 28684 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 28742 Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844 P S E + G DGGG++ Sbjct: 28743 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772 Score = 39.7 bits (91), Expect = 0.029 Identities = 71/346 (20%), Positives = 136/346 (39%), Gaps = 57/346 (16%) Query: 869 VRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRAN 928 ++ + K++V + E +VE + G+K K L E K P E++ ++ Sbjct: 10900 LKAIPKKKVPEKPQVPE-----KVELTPLKVPGGEKKVRKLLPER--KPEPKEEVVLKSV 10952 Query: 929 LQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTSKTPVPEKVPPP 974 L++ + +PK ++ KV P ++V+ +V ++ K P P KVP Sbjct: 10953 LRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--RKIPEPTKVPEI 11010 Query: 975 KPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAET 1034 KPA P LPA E A+ P +P+ PV P Sbjct: 11011 KPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIAAPV--TVPVVG 11054 Query: 1035 LKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQ 1094 K A E KP G P + + + ++ + + G + + + Sbjct: 11055 KKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLK 11111 Query: 1095 GTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKTLKTT---KFII 1145 F ++++D+ + E G + +C VS P+T I W +G ++ + +FI Sbjct: 11112 AVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSNIRESPKHRFIA 11168 Query: 1146 LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 ++ L + ++ + D G Y CV + + + ++ V++ P Sbjct: 11169 DGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 11211 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Query: 1788 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V Sbjct: 11991 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 12049 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 WFKD + I+ S++ I D LI+ D +YTC Sbjct: 12050 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 12089 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73 PSR + ++ EAP L + L +K G + V G PEP++TW + + Sbjct: 13672 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 13731 Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 R ++ + ++ I D G Y EA N G VE+ V Sbjct: 13732 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780 Score = 39.7 bits (91), Expect = 0.029 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + + +P P V+W +G V+ + + + D S +L + K+ D+G Sbjct: 14398 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 14456 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y+ T N G + S ++V + + ++ S + + +G +L + Sbjct: 14457 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 14516 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597 R T++ P+ + V +D +P + A N +G Sbjct: 14517 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 14560 Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657 E PV P P D++V + + MT+ + PP L Sbjct: 14561 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 14604 Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712 ++G +G + C + + P TYT + E VR + + Sbjct: 14605 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 14662 Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 EP T P P S+ G + + +I+G P+PT+ W++D Sbjct: 14663 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 14716 Score = 39.7 bits (91), Expect = 0.029 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L I+ G GR G P+P+V+W ++ + R + T +L D Sbjct: 16828 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 16886 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 GKY N +G+R+ ++ V + G PV + F + W Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 16938 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221 +K+ ++++ ++G+ V + + + +VS + + IH Sbjct: 16939 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987 Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273 N G+ LV + SM A+ + D+ ++ V E ++ D K Sbjct: 16988 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 17040 Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317 +TN I ++ + S A +K+ C R + P PP Sbjct: 17041 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 17100 Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373 + +K K SP P+ S +T Q R + G V G+E R Sbjct: 17101 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 17160 Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420 A P + P T+ G +D K + G+ D A K +P Sbjct: 17161 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 17220 Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 + Q +K T++ + G+P P+V W E + I+V GS L + Sbjct: 17221 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 17277 Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499 A D G YS T N G + S Sbjct: 17278 NAAHEDGGIYSLTVENPAGSKTVS 17301 Score = 39.7 bits (91), Expect = 0.029 Identities = 23/81 (28%), Positives = 34/81 (41%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VVK G RF I G P P W ++ +V N VL I + D G Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 17579 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y V N +G +++ L++ Sbjct: 17580 EYQITVSNAAGSKTVAVHLTV 17600 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 +++ A + + + P V EAP L + + ++ G +A+ +G P Sbjct: 23993 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 24052 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P++TW R T + ++ G+ T L I D GKY + N SG++ V Sbjct: 24053 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 24109 Query: 121 LTV 123 + V Sbjct: 24110 VKV 24112 Score = 39.7 bits (91), Expect = 0.029 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L L VS PP I W+ G L + I ++ SL + ++K D G Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 29513 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y A+N +G+ + V V D P Sbjct: 29514 KYTIEAENQSGKKSATVLVKVYDTP 29538 Score = 39.3 bits (90), Expect = 0.037 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779 P F +SV G + I+G P P V W RDG+ + T ++ ++ L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839 + V ++G+Y + N G+ + L+++ +A P + L + Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116 Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893 G R G P + DG +++ L ++ E Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174 Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953 ++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231 Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005 RS+ + G + +P K PP P P RS + K +L + S Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287 Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032 S P+ + + P PV + PA Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V + P KP D+ V+EG P P V W KD + ++ S + Sbjct: 14376 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 14435 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 D + L + D YT N LG AT + + V Sbjct: 14436 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%) Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575 SV ++ G+ + V G PVP W + R + +EL I+DAL Sbjct: 15109 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 15168 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 +DHG Y A N+ G +A V V + +L + P + L SD + Sbjct: 15169 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 15223 Query: 636 DGSQVT 641 GS++T Sbjct: 15224 GGSEIT 15229 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785 G + I I G P P W DGKA KD H E +N V +++ + + Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 15882 Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810 H G+Y I KN+ G+ +C+V +M Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVM 15909 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725 D HFE G H + + G ++ E S G + + V P P + Sbjct: 22495 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 22551 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785 ++ G+S + I G P PT+ W++ + L +T E+ + +L +K Sbjct: 22552 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 22607 Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809 +G Y + KN GE S V++ Sbjct: 22608 RVDSGNYILKAKNVAGERSVTVNV 22631 Score = 38.9 bits (89), Expect = 0.049 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 ++V +G A K G + WFKD Q + ++I + + IIS D Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE-KKDS 4646 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 +YT + N +G ++C A + V Sbjct: 4647 GEYTFEVQNDVGRSSCKARINV 4668 Score = 38.9 bits (89), Expect = 0.049 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 1/81 (1%) Query: 1819 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1878 + + S F ++G P ++ WFKDD + I E L + V Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASKTG 5398 Query: 1879 KYTCKAVNSLGEATCTAELIV 1899 +YTC N +G +CT L+V Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLV 5419 Score = 38.9 bits (89), Expect = 0.049 Identities = 21/81 (25%), Positives = 35/81 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + V G + + +V G P P++ W G + + Q + L I+E D G Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977 Query: 692 TYTCEAWNSAGEVRTQAVLTV 712 Y A NS+G + A++ V Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV 17998 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 SV A G+ V + G P PTV W +D K L D + + + L + +V Sbjct: 27280 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 27338 Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 G+Y + ++N VGE SS ++ PA+C+ L Sbjct: 27339 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 27372 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT + Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 27637 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 +NA+ +++ V L P PSKP PI Sbjct: 27638 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 27664 Score = 38.5 bits (88), Expect = 0.064 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%) Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 G E+ T + PAP P PP ++ ++ V GESV L ++G T TW + Sbjct: 921 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 978 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 QI+ S ++ ++L I A E G +T N+ G+ L V Sbjct: 979 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032 Score = 38.5 bits (88), Expect = 0.064 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 PV ++P P + + +++M G + + V+G P P +W E+ + + Sbjct: 15092 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 15150 Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 + GT+ L I++ +D G Y A NS G Sbjct: 15151 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183 Score = 38.5 bits (88), Expect = 0.064 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98 L +K G T + E VRG P P+V W ++ +T R +D + FSL Sbjct: 18211 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 18268 Query: 99 EDRGKYTCEATNGSGA 114 D GKY ATN +G+ Sbjct: 18269 SDGGKYVVTATNTAGS 18284 Score = 38.5 bits (88), Expect = 0.064 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%) Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++ Sbjct: 19689 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 19741 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515 + +L D+G Y T N+ G+ + ++V + V E++ Sbjct: 19742 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 19801 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V + +I+G ++ V+ R +W + T E + + Sbjct: 19802 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 19852 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 + AEN G + + +R + V S+ P+ DLKV Sbjct: 19853 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 19893 Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691 S+ + ++ G P G+ I DF E+ Q SL +Q + T Sbjct: 19894 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 19947 Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744 T+ A N GE T + +TV D P K A + + I Sbjct: 19948 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 20006 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P+V W + L DT V + TL++ Q AG+Y I LKN G Sbjct: 20007 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065 Query: 805 CQVSL 809 +S+ Sbjct: 20066 GTISI 20070 Score = 38.5 bits (88), Expect = 0.064 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 PAF L + G K + G P P VTWH++ P+ R + L Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 22206 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I ED G Y + TN +G T+ + V G + + D + Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 22261 Query: 153 PSIWGECPPKF 163 WG PPK+ Sbjct: 22262 ---WG--PPKY 22267 Score = 38.5 bits (88), Expect = 0.064 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 RD VV G R + + G P P + W + D+ I ES +I + D LI+ D Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 23690 Query: 1875 DDDAKYTCKAVNSLG 1889 D +Y +A N G Sbjct: 23691 IDGGQYILRASNVAG 23705 Score = 38.5 bits (88), Expect = 0.064 Identities = 22/83 (26%), Positives = 37/83 (44%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + K G I+GRP P+VTW + L+ + RVS++ L + + D G Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 28716 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y + N +G + S + + G Sbjct: 28717 RYFLTLENTAGVKTFSVTVVVIG 28739 Score = 38.1 bits (87), Expect = 0.083 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%) Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 PV W+ +N +PI+ + E GV +P+ A NA+G Sbjct: 14325 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 14368 Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658 + S SE ++ P KPT + D+ V++G ++++ V P P V W Sbjct: 14369 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422 Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717 +G E++ S+ + L + + D G YT N G V + P Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 14480 Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771 P K +T S SC + +P P +H++ + + + T + V+ Sbjct: 14481 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 14530 Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 E+ + +K + P + + N+VG Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 14560 Score = 37.7 bits (86), Expect = 0.11 Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 45/198 (22%) Query: 47 GATAKFEGRVRGYPEPQVT-WHRNGQPITSGG--RFLLDCGIRGTFSLVIHAVHEEDRGK 103 G++A FE V P +T W ++G I RF+ D R L I V D G+ Sbjct: 11133 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDR---KLHIIDVQLSDAGE 11187 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163 YTC G+ + T +L VE E P +F Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVE---------------------------------ELPVRF 11214 Query: 164 ATKLGR-VVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIH 221 L V V +GQ SC++ + V W K G + ++ R+ M+ L I+ Sbjct: 11215 VKTLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 11272 Query: 222 GVNQDDVGVYTCLVVNGS 239 + D G YT V N + Sbjct: 11273 DADDTDAGTYTVTVENAN 11290 Score = 37.7 bits (86), Expect = 0.11 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%) Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672 PT + L D +KV G V + V+G P P++ W N I++ D Sbjct: 15395 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 15454 Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704 + + L I + ED GTYT A N G V Sbjct: 15455 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 15486 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/73 (27%), Positives = 33/73 (45%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V++K G+ R ++GRP P + W K L+ +A++ + + L + D G Sbjct: 21471 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 21530 Query: 230 VYTCLVVNGSGKA 242 YT N G A Sbjct: 21531 AYTLTATNPGGFA 21543 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86 +AP L P+ + + G T E +RG P P V W ++G+ + + R + I+ Sbjct: 24703 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 24762 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 T +LV+ D G+Y + +N G + + + + V Sbjct: 24763 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 24798 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663 PS+ T PI ++ + D+K D G + + ++G P P + W +G EI Sbjct: 25771 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 25830 Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 +E L +++ DTG Y N AG Sbjct: 25831 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 25869 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/83 (24%), Positives = 38/83 (45%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 + G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28029 Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191 AKN +G A+ +V V D P Sbjct: 28030 TVEAKNASGSAKAEIKVKVQDTP 28052 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1876 ++++ G R + G P P VW K++ + + R + D G S LII D D Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 15170 Query: 1877 DAKYTCKAVNSLGEATCTAELIV 1899 +Y A NS G A + V Sbjct: 15171 HGRYVITATNSCGSKFAAARVEV 15193 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+ Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 17976 Query: 790 GQYEILLKNRVG 801 G+Y I KN G Sbjct: 17977 GKYIISAKNSSG 17988 Score = 37.4 bits (85), Expect = 0.14 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L +V G P+P ++W +G +P + + + + L + +D G YT Sbjct: 19310 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369 Query: 585 AENALGQVSCSAWVTVHEK 603 AEN+ G S + + V +K Sbjct: 19370 AENSSGSKSATIKLKVLDK 19388 Score = 37.4 bits (85), Expect = 0.14 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%) Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78 VDP R+ P + + + G + K + + G P P + W + Q +++ R Sbjct: 22538 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 22589 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + T SL + D G Y +A N +G R VTV + V G V+S Sbjct: 22590 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 22648 Query: 139 TLGDR 143 ++ Sbjct: 22649 VTAEK 22653 Score = 37.4 bits (85), Expect = 0.14 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480 V+ + + G P PE+ W R+EG +V + G +Y L + Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 24088 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y N+ G S T++V + LAV EV + ++ + +I+G V Sbjct: 24089 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 24148 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 + R YA + + +++ + +AEN G Sbjct: 24149 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 24196 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 V V + + +E P P K T + D SQ + ++ PE Sbjct: 24197 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 24237 Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703 H+G + +GT+ +C V +G + +A+N G+ Sbjct: 24238 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 24293 Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762 + + D T QP + + G+ + I + G P P + W++DG+ L Sbjct: 24294 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 24352 Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 K T V + L +K+ G+Y + N G + +S+++ Sbjct: 24353 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401 Score = 37.4 bits (85), Expect = 0.14 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%) Query: 1791 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 D S + +A+E+ +P F S+ + L V G++ G P P V+W K D Sbjct: 26167 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 26225 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 +R + D SL I + +D KYT N L A+ T L+V+ ++ Sbjct: 26226 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 26276 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97 P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ + Sbjct: 26482 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 26540 Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137 D G+Y A N SG + + + V G V+S Sbjct: 26541 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y + Sbjct: 27973 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 28031 Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819 KN G ++ + +Q++ + + Sbjct: 28032 EAKNASGSAKAEIKVKVQDTPGKVV 28056 Score = 37.0 bits (84), Expect = 0.19 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%) Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137 + H G + + P + V V EG+ +C+V+ P + W LNG+ Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880 Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195 ++ +K + +G + + I D G K A+N G E ++ + S Sbjct: 1881 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1939 Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 +APE RP+ + + + +P T K + + + +KV ES Sbjct: 1940 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1995 Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290 EL K + IT +K RK+ + E + K +E Sbjct: 1996 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2055 Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340 G K+TI L+ E + + +G A + VV KPDP Sbjct: 2056 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2109 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400 WY + IE D W E C ++D+ + Sbjct: 2110 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2147 Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451 V+AIN+ G + Q +L T ++ ++ KD + + + EP V + Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2207 Query: 1452 VTINTEQKVSDFY 1464 E D Y Sbjct: 2208 YKDGMEVHEGDKY 2220 Score = 37.0 bits (84), Expect = 0.19 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%) Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994 P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + + Sbjct: 1917 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1962 Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054 +T K V K + + K E + + + T + A Sbjct: 1963 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 2013 Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101 LKS K+E +++ + H T+ EK++ E + T P FK Sbjct: 2014 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2073 Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152 +++Q V +G + +V P W NG K ++ + E ++ Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178 C + I ED A N AG+ Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGE 2159 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + VSG PPP V W N NE ++ E S+ I+ G Y+ Sbjct: 16539 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 16596 Query: 697 AWNSAGEVRTQAVLTV 712 A N AGE + ++ V Sbjct: 16597 AKNEAGERKKTIIVDV 16612 Score = 37.0 bits (84), Expect = 0.19 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1870 T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I Sbjct: 17913 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 17969 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA 1895 + D KY A NS G A +A Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSA 17994 Score = 37.0 bits (84), Expect = 0.19 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 1800 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1853 V E+ VK K + DL+ V G R + + G P PEV W KD + +R Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246 Query: 1854 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++ D + S ++ D KY A N+ G A + V Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293 Score = 37.0 bits (84), Expect = 0.19 Identities = 22/92 (23%), Positives = 40/92 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G ++ + V G P P W +E+ S + + L I++V +D+G Sbjct: 18908 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 18967 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723 Y+ A NS+G + + V + QP F Sbjct: 18968 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 18999 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 + + G + R I+G P PEV W K D IR++ + SL++ +V D Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 23008 Query: 1878 AKYTCKAVNSLG 1889 KYT NS G Sbjct: 23009 GKYTLTLENSSG 23020 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 1809 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1865 P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 26928 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 S++I D + Y K N++G A+ T Sbjct: 26929 SILIKDADRLNSGCYELKLRNAMGSASAT 26957 Score = 37.0 bits (84), Expect = 0.19 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V + G + I+G+P P + W K + LQ +A V V + + I ++ + G Sbjct: 26882 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 26941 Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254 Y + N G A SA + +Q LD Sbjct: 26942 CYELKLRNAMGSA--SATIRVQILD 26964 Score = 36.6 bits (83), Expect = 0.24 Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 2/77 (2%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 ++P + + ++D+ + EG C+ P+ + WF++ + ++ + + + + Sbjct: 8743 IEPAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVH-K 8800 Query: 1867 LIISDVCGDDDAKYTCK 1883 L I+DV +D +YTCK Sbjct: 8801 LTIADVRAEDQGQYTCK 8817 Score = 36.6 bits (83), Expect = 0.24 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%) Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 RF A E R + PK T +VV G+ P+ + W K N PL Sbjct: 12982 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 13041 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + +E+ ++LE + D G Y ++ N GKA L + Sbjct: 13042 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 13086 Score = 36.6 bits (83), Expect = 0.24 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223 V+EG KI G P P +TW K P +P + V + N + V L I Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 16186 Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252 + D G+YT VN G AS L++ G Sbjct: 16187 RRSDTGLYTITAVNNLGTASKEMRLNVLG 16215 Score = 36.6 bits (83), Expect = 0.24 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586 G L ++G P P++TW + AR ++L I++A ED G Y+ E Sbjct: 17233 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 17292 Query: 587 NALGQVSCSAWVTVHEK 603 N G + S V V +K Sbjct: 17293 NPAGSKTVSVKVLVLDK 17309 Score = 36.6 bits (83), Expect = 0.24 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%) Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643 A+N G +S + T + K EY P PT L + G + + Sbjct: 20350 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 20400 Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703 + + G P P+ W G +I+ S+ T L I+ +D G YT A N G Sbjct: 20401 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 20460 Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 +TV + P IS + A+L Sbjct: 20461 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 20491 Score = 36.6 bits (83), Expect = 0.24 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 26547 Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725 A NS+G + ++ + P T P IS Sbjct: 26548 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580 Score = 36.6 bits (83), Expect = 0.24 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 1794 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1850 +AF + +E P ++P T +++ GS D I G P P+V W ++ ++ Sbjct: 28631 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 28689 Query: 1851 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 E+ I +D +L + D D +Y N+ G T + ++V Sbjct: 28690 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737 Score = 36.2 bits (82), Expect = 0.32 Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F K + D + +G + G P V W K+ ++ S+ I E + L I Sbjct: 7870 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIP 7928 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +D +Y C N+ G+ +C+A++++ Sbjct: 7929 SSTVEDAGQYNCYIENASGKDSCSAQILI 7957 Score = 36.2 bits (82), Expect = 0.32 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128 NC+ G D N K S P + L+DV V G+ C++S + Sbjct: 12167 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 12225 Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174 + W L GK L+ + ++ EG + ++++ ED G + AK+ Sbjct: 12226 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 12271 Score = 36.2 bits (82), Expect = 0.32 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%) Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G Sbjct: 16843 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 16901 Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 + V V P SF V KD VI Sbjct: 16902 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 16931 Score = 36.2 bits (82), Expect = 0.32 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 ++ + G++ + + G P PT+ WLR K + +++ E+ + L++K Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 23692 Query: 789 AGQYEILLKNRVGECSCQVSL 809 GQY + N G S V++ Sbjct: 23693 GGQYILRASNVAGSKSFPVNV 23713 Score = 35.8 bits (81), Expect = 0.41 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1867 P F + L VV G A IEG V W K+ ++ IRES + +I + E+ +L Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATL 5668 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + + KY C+ N G A L+V Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700 Score = 35.8 bits (81), Expect = 0.41 Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDD 1876 + V G+ +C + G P+ WFKD + + +S+H ++ + + +++ D Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM--SD 6711 Query: 1877 DAKYTCKAVNSLGEATCTAELIV 1899 Y+ + NS+G++ CT + V Sbjct: 6712 KGLYSFEVKNSVGKSNCTVSVHV 6734 Score = 35.8 bits (81), Expect = 0.41 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%) Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 T S ++ + E ++ +A N G + ++ L V + D P Sbjct: 15351 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 15395 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204 ++ R S+ G+ + VK G+ +TG P P++ W K ++ Sbjct: 15396 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 15445 Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260 + VS L I ++D G YT N G + + + S R+ Sbjct: 15446 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 15505 Query: 261 VRETKA 266 V + KA Sbjct: 15506 VTDIKA 15511 Score = 35.8 bits (81), Expect = 0.41 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G +V I G P PT W DG + K H+ V + L +K G+Y+I Sbjct: 17525 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583 Query: 795 LLKNRVGECSCQVSL 809 + N G + V L Sbjct: 17584 TVSNAAGSKTVAVHL 17598 Score = 35.8 bits (81), Expect = 0.41 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 EAP +L P L IK G T + G P P+ +W + G+ I + Sbjct: 20374 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + + +A + D G+YT ATN G + V++TV Sbjct: 20434 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 20469 Score = 35.8 bits (81), Expect = 0.41 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584 G + ++ V G P P +TW Q ++ + A L+I + + D G Y Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 A N +G+V + VH+ P PT PI Sbjct: 21140 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 21166 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 23010 Query: 104 YTCEATNGSGARQVTVELTV 123 YT N SG + V + V Sbjct: 23011 YTLTLENSSGTKSAFVTVRV 23030 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P+ LP +K K + +G P+ V W ++GQ + R + + SL Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 25453 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I +ED G Y +N +G+ +TV +T+ Sbjct: 25454 IKEASKEDVGTYELCVSNSAGS--ITVPITI 25482 Score = 35.8 bits (81), Expect = 0.41 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 1833 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 +G P P V W KD++++ + I+ + D + L I V +D KY N +GE Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 27352 Score = 35.8 bits (81), Expect = 0.41 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142 +T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + + Sbjct: 33315 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 33374 Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + L ++ I +D GLY N+ G + + + Sbjct: 33375 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420 Score = 35.4 bits (80), Expect = 0.54 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L ++ V+E + L C+VS P A +IW + + T + EG + I+ Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 12523 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219 A ED G Y C R P S +D Sbjct: 12524 AHLEDAGNYNC---------------------------------RLPSS--------RTD 12542 Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279 VK + + I P++ ++ GE E ++ + W + K ++ Sbjct: 12543 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 12592 Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 + V L + A + G Y ++V G+ +A +LTV++K Sbjct: 12593 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 12639 Score = 35.4 bits (80), Expect = 0.54 Identities = 16/82 (19%), Positives = 37/82 (45%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 ++ ++ G+ + + +G+P+P+V+W K + R + LE + D Sbjct: 16827 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 16886 Query: 229 GVYTCLVVNGSGKASMSAELSI 250 G Y +V N +G ++++ Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV 16908 Score = 35.4 bits (80), Expect = 0.54 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676 KP + L G+ L V G + + V G P PEV W + ++ S + R Sbjct: 18200 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 18257 Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + + D G Y A N+AG A + V Sbjct: 18258 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293 Score = 35.4 bits (80), Expect = 0.54 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 + +A+NA G +S + T + K E LP P + + V G Sbjct: 23593 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 23643 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 + V G P P + WL EI+ES + + L +++ D G Y A N Sbjct: 23644 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 23703 Query: 701 AG 702 AG Sbjct: 23704 AG 23705 Score = 35.4 bits (80), Expect = 0.54 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + +K G K + G P P ++W ++G I R + T L + D Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 25857 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157 G+Y N +G R V V V G ++ ++ S P + I Sbjct: 25858 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 25917 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205 K T + EG++ SCK+T LKGN + +P Sbjct: 25918 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 25970 Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 V++ + V LEI V ++ + + C S S + I+ + + Sbjct: 25971 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 26028 Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314 +VR K D+R + T + E ++ + AA S S R P + P Sbjct: 26029 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 26084 Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373 PP + K+ +S K + A P+ + + + + S G E Sbjct: 26085 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 26144 Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430 A + R +G+ D S +++ +I E + + F ++ VK + Sbjct: 26145 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 26203 Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490 G P P V W T +R + ++ + S L + A DSG Y+ T Sbjct: 26204 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 26260 Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526 N S + ++V + V K+ AV+ Sbjct: 26261 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 26296 Score = 35.4 bits (80), Expect = 0.54 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V++G + R + I G+P P W K + A ++ SE + L I ++ D G Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 30203 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y ++ N GK ++ ++ + G Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIG 30226 Score = 35.4 bits (80), Expect = 0.54 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1867 P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 32431 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 I D DD Y N GEA+ A L V Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D++V E A+F+C++ P W K Q I F++ D + S++I Sbjct: 11842 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 11899 Query: 1871 DVCGDDDAKYTCKA 1884 +D+AKY +A Sbjct: 11900 SAAFEDEAKYMFEA 11913 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 R+VV G + R ++G+P P VTW L A + + + V I + Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 16590 Query: 229 GVYTCLVVNGSGK 241 GVY+ L N +G+ Sbjct: 16591 GVYSLLAKNEAGE 16603 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 ++ G + VRG P P+VTW + G + G L+D LVI +D Sbjct: 18618 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 18673 Query: 102 GKYTCEATNGSGARQVTVELTV 123 GKY+ N +G + V V + V Sbjct: 18674 GKYSLTLVNPAGEKAVFVNVRV 18695 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 L V G+ D + G P P V W KD ++ + ++ + C+L + V D Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 YT A NS G + T +L V Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385 Score = 35.0 bits (79), Expect = 0.70 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%) Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 VA AP + L+GL DL + + S + + + G P P V W + + Sbjct: 19972 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 20031 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721 E +L + + D G YT N AG + T ++ V +P T P Sbjct: 20032 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 20082 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%) Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201 D + AP + P+I K G +V + I G+P P+ +W K + Sbjct: 20371 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 20420 Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 +PS ++ +L I + D G YT N G Sbjct: 20421 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 +V G ++ + I+G P P V RDG L K T F + T+ LK+ Sbjct: 26485 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 26543 Query: 789 AGQYEILLKNRVGECSCQVSLML 811 AG+YEI N G +++++ Sbjct: 26544 AGRYEITAANSSGTTKAFINIVV 26566 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565 V+++ ++ V+K A G L+ + G P P I W + + +Q C + Sbjct: 26871 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 26927 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 A + I+DA + G Y NA+G S + V + +K Sbjct: 26928 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 26965 Score = 34.7 bits (78), Expect = 0.92 Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 ++V G A + + G P+ + W+KD + + S+ ++I + ++ L D Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDS 4084 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 +YT + N +G ++C V Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106 Score = 34.7 bits (78), Expect = 0.92 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V P+ W G PV + + E+ G Y Y A N QG Sbjct: 13624 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 13670 Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553 S T +++ + E F V L V G L +V G P P+ITW Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730 Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 + Q R T E + + I D+ D GTY A N G+ + V V +K Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 13783 Score = 34.7 bits (78), Expect = 0.92 Identities = 16/67 (23%), Positives = 28/67 (41%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + G P P + W+ E+ + + SL +++ D+G Y + Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 22617 Query: 697 AWNSAGE 703 A N AGE Sbjct: 22618 AKNVAGE 22624 Score = 34.7 bits (78), Expect = 0.92 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451 +SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G Sbjct: 23604 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 23662 Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 + E+ L + A D G Y ASN G S Sbjct: 23663 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 23708 Score = 34.7 bits (78), Expect = 0.92 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ AT + ++G PEP+V W + +T + + +F+ LVI V D G Sbjct: 25119 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 25174 Query: 103 KYTCEATNGSGARQVTVELTV 123 +Y N SG++ V + V Sbjct: 25175 RYNLTLENNSGSKTAFVNVRV 25195 Score = 34.7 bits (78), Expect = 0.92 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 +KP V + D +G P V W KD Q+++E+ + + S Sbjct: 25393 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 25451 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + +D Y NS G T +IV Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484 Score = 34.3 bits (77), Expect = 1.2 Identities = 47/193 (24%), Positives = 71/193 (36%), Gaps = 18/193 (9%) Query: 1717 PWLMKDTKNMEAKKLSKDRMKKYMA-----RRKWQKTGNAVRAIGRLSSMAMISGLSG-- 1769 P+ K +N+++ R+ +A R W K G + A R +A + G + Sbjct: 4113 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR-IAFVEGTASLE 4171 Query: 1770 --RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR 1827 R + A +D S A + V E V SK +V+ GSA Sbjct: 4172 IIRVDMNDAGNFTCRATNSVGSKDSSGALI--VQEPPSFVTKPGSK-----DVLPGSAVC 4224 Query: 1828 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1887 +G + WFK ++ + I E SL + V D YTCK N Sbjct: 4225 LKSTFQGSTPLTIRWFKGNKELVSGGSCYIT-KEALESSLELYLVKTSDSGTYTCKVSNV 4283 Query: 1888 LGEATCTAELIVE 1900 G C+A L V+ Sbjct: 4284 AGGVECSANLFVK 4296 Score = 34.3 bits (77), Expect = 1.2 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 5/97 (5%) Query: 1771 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKT-IRDLE---VVEGSAA 1826 K S T L E++E E + F E V+ + + T I+D+E V++ + A Sbjct: 8614 KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA 8673 Query: 1827 RFDCKIE-GYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 F+ I+ YP+ ++ W+K + + S F+I D D Sbjct: 8674 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 8710 Score = 34.3 bits (77), Expect = 1.2 Identities = 45/214 (21%), Positives = 87/214 (40%), Gaps = 40/214 (18%) Query: 879 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLK-EIPA----------EQMDFRA 927 +R+ EE ++ +V ++ + ++ +K S + E+ ++ ++PA E+M F + Sbjct: 9193 SRRMEEEKVQVTKVPEVS-KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251 Query: 928 NLQRQVK---PKTVSE--EERKVH---------SPQQVDFRSVLAKKGTSKTPVPEKVPP 973 + + +V P+ E E K+H P+ + A + + P+P+KV P Sbjct: 9252 HTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEP 9311 Query: 974 PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQ-PSGPLKPVGNAKPA 1032 P P P+ KK +P E V +P + + P P KPV K Sbjct: 9312 PAPKVPEV-----PKKPVPEEK--------KPVPVPKKEPAAPPKVPEVPKKPVPEEKIP 9358 Query: 1033 ETLKPMGNAKPAETLKPMGNAKPDENLKSASKEE 1066 + A PA+ + +E + ++ E Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQRE 9392 Score = 34.3 bits (77), Expect = 1.2 Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 25/139 (17%) Query: 136 VSKTLGDRFSAPAVETRPSIWGECPP--------------KFATKLGRVVVKE----GQM 177 V K A + RP GE PP KF ++ +++ E G Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSS 11135 Query: 178 GRFSCKITGRPQPQVT-WLK--GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234 F C ++ P +T W+K N+ P R K+ + L I V D G YTC+ Sbjct: 11136 AIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKD--RKLHIIDVQLSDAGEYTCV 11191 Query: 235 VVNGSGKASMSAELSIQGL 253 + G+ + + +A+L ++ L Sbjct: 11192 LRLGNKEKTSTAKLVVEEL 11210 Score = 34.3 bits (77), Expect = 1.2 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 ++D V E F+C++ + WF+++++I +S + I +D +L I D Sbjct: 12646 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 12703 Query: 1875 DDDAKYTCKAVNSLGE-ATCTAELIVE 1900 DD A Y N GE A LIVE Sbjct: 12704 DDQANYNVSLTNHRGENVKSAANLIVE 12730 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%) Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470 +A PK ++ Q V + + PK E WF E P+ + +I+ + S Sbjct: 12997 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 13053 Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523 +L+A+ D G Y N G+ L+ V L V E S+ + Sbjct: 13054 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 13112 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549 + +G ++ V + R TW+L Sbjct: 13113 PLTDGGSKIIGYVVERRDIKRKTWVL 13138 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57 G+ L S +K +S DPS + PLT AF+ P +L K+G + Sbjct: 13359 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 13416 Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 GYP P TW + + +G R + + LVI D+G YT + N Sbjct: 13417 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 13471 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225 G + VK G R + G+P P+V W K L S RV + + + + Sbjct: 18209 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 18268 Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250 D G Y N +G A +++ Sbjct: 18269 SDGGKYVVTATNTAGSFVAYATVNV 18293 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%) Query: 1812 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1871 S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D Sbjct: 24028 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 24083 Query: 1872 VCGDDDA-KYTCKAVNSLG 1889 C +DA KY K NS G Sbjct: 24084 NCDRNDAGKYILKLENSSG 24102 Score = 34.3 bits (77), Expect = 1.2 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%) Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77 P V + E P + L R + +++G + ++G P P W + GQ I+ Sbjct: 30122 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 30179 Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126 R ++ T LVI D G Y N G + V +++ V GS Sbjct: 30180 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 30227 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G + I ++G P PTV W + + L ++ + ++V+K Q H Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 16590 Query: 790 GQYEILLKNRVGE 802 G Y +L KN GE Sbjct: 16591 GVYSLLAKNEAGE 16603 Score = 33.9 bits (76), Expect = 1.6 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%) Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 +RG PVP W +G I ++ + + L I++ L D G Y NA G + Sbjct: 17534 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 17593 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + +TV + P PT PI ++D + MT +S PP + Sbjct: 17594 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 17630 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 G A R + + G P P + W KD + + + +I D + +L+ D D YT Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 21534 Query: 1883 KAVNSLGEA 1891 A N G A Sbjct: 21535 TATNPGGFA 21543 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%) Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70 +P+ V P E +LPP + + I+ T + ++G P P+V W R+ Sbjct: 21841 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 21898 Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 G L I T S L++ V+ D GKY N SG++ V + V Sbjct: 21899 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 21948 Score = 33.9 bits (76), Expect = 1.6 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G + + V + G P PEV W EI+++ T SL + V D+G Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 23009 Query: 692 TYTCEAWNSAG 702 YT NS+G Sbjct: 23010 KYTLTLENSSG 23020 Score = 33.9 bits (76), Expect = 1.6 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%) Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75 +++ P V + +T E +P + ++ G E +G P+P ++W ++G P+ Sbjct: 27547 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 27606 Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 F+ +L I +E GKYT N ++ V +TV Sbjct: 27607 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 27651 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%) Query: 1796 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1845 + E++AE ++P I DLE+ + G++ R + G P P + W K Sbjct: 29428 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 29482 Query: 1846 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 Q I + ID E + LI+ V D KYT +A N G+ + T Sbjct: 29483 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 29529 Score = 33.5 bits (75), Expect = 2.0 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 3/132 (2%) Query: 916 KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTP-VPEK-VPP 973 KE+ E++ F + V+ V EEE +H ++ + K P VP K VP Sbjct: 9901 KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960 Query: 974 PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAE 1033 K P + K+P E E + + KP P P KPV K Sbjct: 9961 EKKPVPVPKKKEAPPAKVP-EVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPV 10019 Query: 1034 TLKPMGNAKPAE 1045 + A PA+ Sbjct: 10020 PVPKKVEAPPAK 10031 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D V EG A F C++ + VVWFK+D + SR I E L + Sbjct: 11576 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 11633 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +V DD ++ + + E + TA+L V Sbjct: 11634 EVTLDDISQIKAQ----VKELSSTAQLKV 11658 Score = 33.5 bits (75), Expect = 2.0 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+ Sbjct: 11931 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 11988 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCT 1894 D+ DD ++ +A+ EA T Sbjct: 11989 DLSIDDTSQIRVEAMGMSSEAKLT 12012 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/72 (27%), Positives = 32/72 (44%) Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244 TG P+P TW G+ L+ RV + + L I + D G+YT + N S Sbjct: 13419 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478 Query: 245 SAELSIQGLDSA 256 ++++ SA Sbjct: 13479 EIDVNVIARPSA 13490 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%) Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69 S IS+ ++ DP P L ++ + EG R P P V+WH++ Sbjct: 14372 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 14423 Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125 G+ + + R + V +V D G YT N G+ ++ + V G Sbjct: 14424 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 14478 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582 G L+ VRG P P + W + RS A ++ + A D G Y Sbjct: 18216 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 18275 Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621 A N G A V V +K ++ ++ V+ + T Sbjct: 18276 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 18314 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96 + L ++ G T + V+G P P++TW + + R LD I+ T F + V Sbjct: 19701 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 19756 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 ++ D GKY N G ++ T+ + V Sbjct: 19757 NKYDAGKYILTLENSCGKKEYTIVVKV 19783 Score = 33.5 bits (75), Expect = 2.0 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 VK V S S S DP E P F + + L +K GA+ RG P Sbjct: 26157 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 26214 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P V W + + + R +D T SL I + D GKYT N A +T+ Sbjct: 26215 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 26271 Query: 121 LTV 123 + V Sbjct: 26272 VKV 26274 Score = 33.5 bits (75), Expect = 2.0 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572 S + K V G F + RG PVP + W +P R+ + L I++ Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 26246 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600 A D G YT +N L S + V V Sbjct: 26247 ANRNDSGKYTLTIQNVLSAASLTLVVKV 26274 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 26253 Query: 692 TYTCEAWN 699 YT N Sbjct: 26254 KYTLTIQN 26261 Score = 33.1 bits (74), Expect = 2.7 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G KL+ + +LSV+ ++ I R+L E FE + + Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2560 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W+ + I ++ ++ + + L + + ++D GKYT A G + +L Sbjct: 2561 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2615 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 TV G +SK L D+ V E Q F Sbjct: 2616 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2640 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C++ P + WL+ L + + + L I DD+G YT V Sbjct: 2641 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2699 Query: 242 ASMSAE 247 A + E Sbjct: 2700 AKLKVE 2705 Score = 33.1 bits (74), Expect = 2.7 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 1776 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1821 S T +++E + ++ + L+ +++ K VK PYF+ + D V Sbjct: 11616 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 11675 Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E C++ D V WFKD + I S + I D L I D +Y Sbjct: 11676 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 11732 Query: 1882 CKAVNSLGEATCTAE 1896 C +A T E Sbjct: 11733 CDCGTDKTKANVTVE 11747 Score = 33.1 bits (74), Expect = 2.7 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%) Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501 K EV W L V Q ++ + H L + + RD G Y A + + + Sbjct: 12939 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 12995 Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561 + AP + +D V G+ + P W +P+ Sbjct: 12996 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 13047 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591 A I +A D G Y + +N G+ Sbjct: 13048 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 13077 Score = 33.1 bits (74), Expect = 2.7 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160 + V G+ + + V+ P I W+ N + K T + +++E + +SI KA Sbjct: 15408 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 15467 Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 + ED+G Y A N G + V V D P+ Sbjct: 15468 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499 Score = 33.1 bits (74), Expect = 2.7 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 1816 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875 R+ + G R I+G P P+V W K+D+ +ID G+ L I + + Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 17282 Query: 1876 DDAKYTCKAVNSLGEATCTAELIV 1899 D Y+ N G T + +++V Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306 Score = 33.1 bits (74), Expect = 2.7 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575 +D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D + Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 25854 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y +N G S + V +K P P P+ + GL+ Sbjct: 25855 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 25896 Score = 33.1 bits (74), Expect = 2.7 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ GA+ + +G P P W + ++ D +FS L + + D G Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 28424 Query: 103 KYTCEATNGSGARQVTVELTV 123 KYT N SG++ +T + V Sbjct: 28425 KYTLTVENNSGSKSITFTVKV 28445 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 + D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+ Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419 Query: 1875 DDDAKYTCKAVNSLGEAT 1892 +D Y+ + +LG +T Sbjct: 2420 EDAGNYSF-TIPALGLST 2436 Score = 32.7 bits (73), Expect = 3.5 Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F K + D V G + + G V W KD +I S I E C L I Sbjct: 5988 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK-TCILEIL 6046 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 + D +Y+C+ N G C A +V T+E Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGA--LVSTLE 6077 Score = 32.7 bits (73), Expect = 3.5 Identities = 50/218 (22%), Positives = 85/218 (38%), Gaps = 16/218 (7%) Query: 860 WLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIP 919 W E+ E V + R E + E + + EV + ++ +K+ + K + Sbjct: 9495 WSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIIS------KRVE 9548 Query: 920 AEQMDFRANLQRQV--KPKTVSE-EERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKP 976 AE + ++++ KPK ++ EE + + V KK + P EKVPPPK Sbjct: 9549 AEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPK- 9607 Query: 977 ATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKP-AETL 1035 P+ +KK+P + E L AK E ++ + A P A Sbjct: 9608 -VPEEPKKPVPEKKVPPK-VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVP 9665 Query: 1036 KPMGNAKPAE---TLKPMGNAKPDENLKSASKEELKKD 1070 + A P E LKP +P + K +K++ Sbjct: 9666 EEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703 Score = 32.7 bits (73), Expect = 3.5 Identities = 76/338 (22%), Positives = 111/338 (32%), Gaps = 62/338 (18%) Query: 932 QVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSK--------TPVPEKVPPPKPATPDFRS 983 +V K V E++ V +P++V+ + K TPVP+KV P P P R Sbjct: 10034 EVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE 10093 Query: 984 VLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKP 1043 + LP E E + V + L + P + + E L P Sbjct: 10094 PVPVPVALPQEEEVLFEEEI----VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP 10149 Query: 1044 AETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQK 1103 E P E + +EE+ +VK V P K+K Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV----------------PVPAPVPEIKKK 10193 Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI------ 1157 + + V KK PPA + K IIL +E + V + Sbjct: 10194 VTEKKVVIPKK-------EEAPPAKV---PEVPKKVEEKRIILPKEEEVLPVEVTEEPEE 10243 Query: 1158 ----EKALPEDRGLYK-----------CVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202 E+ +PE+ + V K +A V+ PA + K PE K Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303 Query: 1203 SRRP--KSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238 P K PP E V +K P K A+PP Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKV-LVPKKEAVPP 10340 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163 G ++ + + P W +GK K K + L + + I + Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 G Y AKN AGQ +C+V V D P Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKVMDVP 15912 Score = 32.7 bits (73), Expect = 3.5 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1881 GS D + G P+P+++W K D+ + + Y G + + C D KYT Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 29119 Query: 1882 CKAVNSLG 1889 N+ G Sbjct: 29120 LTVKNASG 29127 Score = 32.3 bits (72), Expect = 4.6 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 1816 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1873 ++LE++EG A F C I E +P V W +DD+++ + + D L++ D Sbjct: 12559 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 12614 Query: 1874 GDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y V +G A A L V Sbjct: 12615 LQDMGTY----VVMVGAARAAAHLTV 12636 Score = 32.3 bits (72), Expect = 4.6 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%) Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 P+ AP + L L + G +T + SG P P+V W + ++ E + H Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867 Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702 + T +L ++++ + D+G Y NS G Sbjct: 16868 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 16898 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575 KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+ Sbjct: 21468 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 21526 Query: 576 EDHGTYTCLAENALG 590 D G YT A N G Sbjct: 21527 RDSGAYTLTATNPGG 21541 Score = 32.3 bits (72), Expect = 4.6 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584 G + + + G P+P++T +G P++ AE +++++++ D G Y Sbjct: 26491 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 26550 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635 A N+ G + V ++ P PT P+ + +++ V Sbjct: 26551 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 26597 Query: 636 DGSQVT 641 GSQVT Sbjct: 26598 GGSQVT 26603 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P + L+ +K G+ V + +SG P P + W + E+Q + E S Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 26929 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 + I++ ++G Y + N+ G A + VQ Sbjct: 26930 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 26961 Score = 32.3 bits (72), Expect = 4.6 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 +P + + + G + + G P P +W G + R ++ + L I Sbjct: 29743 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 29801 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 D G+YT E N +G T+++ + Sbjct: 29802 TIRDTGEYTLELKNVTGTTSETIKVII 29828 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 1811 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2233 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + D Y+C V T TA+LIVE Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%) Query: 1745 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1797 W K G V+ I + S M +I ++ K G+ + + A L + VS + Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2445 Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 + + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q Sbjct: 2446 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1870 ++R L +V G R + G P P+V W K D +R+ Q+D D L+I Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 18666 Query: 1871 DVCGDDDAKYTCKAVNSLGE 1890 + DD KY+ VN GE Sbjct: 18667 NSTRDDSGKYSLTLVNPAGE 18686 Score = 32.0 bits (71), Expect = 6.0 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786 R++ G S+ I I G P P V W +D L K+ + E N + FT L++ + Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 20839 Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819 + G++ + ++N G+ S V++ + ++ L Sbjct: 20840 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 20872 Score = 32.0 bits (71), Expect = 6.0 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 +D+ VV G + I G P P+VVW KD + + E+ +L++ D Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773 Query: 1875 DDDAKYTCKAVN 1886 D +Y K N Sbjct: 24774 TDGGQYILKLSN 24785 Score = 32.0 bits (71), Expect = 6.0 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104 K G+ + + G P P+VTW + R + + +L + D G+Y Sbjct: 28660 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 28718 Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164 N +G + +V + V G G VS + E+ WGE Sbjct: 28719 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 28770 Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215 T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+ Sbjct: 28771 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 28823 Score = 31.6 bits (70), Expect = 7.8 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E S R I+G P P V W K + + ++ N +LI+ D D KYT Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 20054 Query: 1882 CKAVNSLG--EATCTAELI 1898 N G E T + +++ Sbjct: 20055 ITLKNVAGTKEGTISIKVV 20073 Score = 31.6 bits (70), Expect = 7.8 Identities = 19/80 (23%), Positives = 30/80 (37%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V +T ++ G P P+V W +G + +E+ L + D G Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y SN G S T++V Sbjct: 24779 YILKLSNVGGTKSIPITVKV 24798 Score = 31.6 bits (70), Expect = 7.8 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694 G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y Sbjct: 24722 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780 Query: 695 CEAWNSAG 702 + N G Sbjct: 24781 LKLSNVGG 24788 >gi|110349717 titin isoform novex-2 [Homo sapiens] Length = 27118 Score = 366 bits (939), Expect = e-100 Identities = 238/812 (29%), Positives = 389/812 (47%), Gaps = 79/812 (9%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154 AP FK++L++++V L C+V+ P + W GK + K+ I +G Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + I +D +Y+ A N G + + V+ Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24715 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 P K +P + +R GE V + +G TW K Sbjct: 24716 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24759 Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 + I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP Sbjct: 24760 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24819 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393 P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V + Sbjct: 24820 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24878 Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453 L Y+FRV A N +G S+PS+ SE T E + E D+ EV + Sbjct: 24879 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24935 Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513 ++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+ Sbjct: 24936 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24994 Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573 N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E + Sbjct: 24995 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 25054 Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633 +++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV Sbjct: 25055 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25114 Query: 1634 NYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAK 1693 ++ + ATDMWS+G + Y+L+SG++PF+ + + + + N+ +A + FD+EAF EIS +A Sbjct: 25115 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25174 Query: 1694 DFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1753 DF+ LL K+ K+R+ ++ LQHPWL + + + K + + ++Y +K N V Sbjct: 25175 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25233 Query: 1754 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1813 + R+S I +S G + + +E VS + AV EE HVK Sbjct: 25234 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25281 Query: 1814 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 + CKIE Y +V W+ + + S ++I Y EDG L + D+ Sbjct: 25282 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25326 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 DD Y CK VN GE + AEL V+ + E Sbjct: 25327 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25358 Score = 164 bits (416), Expect = 6e-40 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%) Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122 +VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++ Sbjct: 26443 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26502 Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171 + S K+ Q T+ + A E S P T L Sbjct: 26503 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26557 Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y Sbjct: 26558 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26617 Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285 TC V N +G S S +L+I+ + V K + + V++E++ + ++ Sbjct: 26618 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26677 Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 EA ++ SK S + S + +K + RT + Sbjct: 26678 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26737 Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388 T SI + R+ + G GV + EE + T +Q Sbjct: 26738 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26795 Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440 + + +SK + + + S P F S+P+SQ + E Q V F CE+SG Sbjct: 26796 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26855 Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS Sbjct: 26856 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26912 Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560 T + L ++E PS VL+ D LQ S + Q +Q + S Sbjct: 26913 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26954 Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613 EA + A + ++ ++ ++S S+++ + S + Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 27014 Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671 A + P SD+ + +G +T+ +G P PEV W G +I QE FH Sbjct: 27015 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 27074 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 E +L I +V +D G YT N G Sbjct: 27075 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27105 Score = 158 bits (400), Expect = 4e-38 Identities = 188/837 (22%), Positives = 311/837 (37%), Gaps = 176/837 (21%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ VA + S +L V+ E P + + + ++ G A+F + G P+ Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221 Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P+++W++ Q +++G + FL D ++L++ ED YTCEA N G + Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 L+VE P V + PP T L V EGQ R Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F C+++G +V+W + ++PS +++ LEI +D G YT + N Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376 Query: 240 GKASMSAELS--IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297 G+ S +A LS +Q LD +++ DVR+ + +S E+ K Sbjct: 3377 GQVSSTANLSLEVQALD---------RQSSGKDVRESAKSQAVADSSFTKEESKISQKEI 3427 Query: 298 SSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP- 356 S Q G S + + V + S S AA VQ Sbjct: 3428 KSFQ-GSSYEY-------------------------EVQVFESVSQSSIHTAASVQDTQL 3461 Query: 357 -RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415 L ++ S E K A + +T + L QDV K + Sbjct: 3462 CHTASLSQIAESTELSKECA--KESTGEAPKIFLHLQDVTVKCGD--------------- 3504 Query: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 T +F C + +V W EG + E ++ ++ +L + Sbjct: 3505 --------------TAQFLCVLKDDSFIDVTWTHEGAKIEESE-RLKQSQNGNIQFLTIC 3549 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 + D G YSC N G+ + S AV+ V + S+L + Sbjct: 3550 NVQLVDQGLYSCIVHNDCGERTTS--------AVLSVEGAPESILHE------------- 3588 Query: 536 SVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQD-ALPEDHGTYTCLAENALGQVSC 594 RI + + +++ S A LH + L + + T L+E+ Sbjct: 3589 --------RIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSES------- 3633 Query: 595 SAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654 V+ K + E T PIF++ +S+ + G T++V V G P P++ Sbjct: 3634 ----PVYPTKFDSEKE---------GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKI 3680 Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ- 713 W NG + S D+ F G HSL I ED G YTC A N G+ A L + Sbjct: 3681 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3740 Query: 714 --EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 754 E H T+ P F+ + + + + G + + G+P PTV W Sbjct: 3741 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTW 3800 Query: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 ++ K LC + + T ++ Q +G Y +N +GE +C L++ Sbjct: 3801 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857 Score = 134 bits (336), Expect = 1e-30 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%) Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 S + P + S+ P + Q V + KF + +G P+P W +G + Sbjct: 26529 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26588 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++ Sbjct: 26589 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26637 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 +KD E Q Q + TP + ++ + Q A + E ++E Q+ L Sbjct: 26638 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26689 Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631 ++ + ++E + S + VHE+ K+S+ SE + A K + + Sbjct: 26690 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26742 Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G Sbjct: 26743 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26800 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751 TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P Sbjct: 26801 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26859 Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 + W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+ Sbjct: 26860 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918 Query: 812 QNSSARALPRGREPA 826 LP EP+ Sbjct: 26919 -------LPLVEEPS 26926 Score = 122 bits (306), Expect = 3e-27 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++ Sbjct: 23846 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23902 Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848 +L+N+ G+ + + + + S P G P +D+ V AD GG+D G Sbjct: 23903 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23958 Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906 + W + VRG +++ E R Q L + V+ Sbjct: 23959 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 24016 Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963 KT L+ + P E +D + + + +V + ++ + K + Sbjct: 24017 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24075 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022 KT + + PD + ++ A+N +ET A + V P G Sbjct: 24076 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24131 Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070 L+ + +K + TL KP K D K ++KE +K Sbjct: 24132 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24191 Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120 +N+ R T + K + G AP +++++DV G+ L CQ Sbjct: 24192 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24250 Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180 + P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E Sbjct: 24251 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24310 Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240 S ++ + P P P K Sbjct: 24311 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24330 Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299 E G ++ L G TW +K +Q SE++ +EN+E+ + L + Sbjct: 24331 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24386 Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG Sbjct: 24387 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24446 Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P + Sbjct: 24447 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24506 Query: 1418 ESELTTVGEKPEEP 1431 S + + E+P Sbjct: 24507 VSSVVIIKSPFEKP 24520 Score = 118 bits (295), Expect = 6e-26 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%) Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680 T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714 I+E F ED+G +TC A N AG V T L VQ Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014 Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759 P + P+FI+KP G SV+ C + G+P P V+W + G Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074 Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ + Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131 Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875 L + ++ + V + G PG+ + + E+E + + K Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186 Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932 V R + E+ QE F + L K++ KT E+ L+E E+M + Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242 Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981 V+ S + ++ + + ++ V S P+P +++ + DF Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298 Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035 R+ L LP + G +A N K NA SG P P+G TL Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350 Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095 +P+ + +L P ++ + A + + + S+ + Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407 Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152 P F K EG+ +V P W +G+ + T +++ ++G+ Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212 S+ I A P D G + VA+N AG++ S +TV+ Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504 Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272 + + P ++ ++ ++ G +E+ + TG W+ Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544 Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327 K I ++ +++E ++ + L I + + YT NK G + + +VN+ V Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604 Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348 +P+P P GT A +I + L Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631 Score = 115 bits (288), Expect = 4e-25 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483 + E Q + + ++G +V W L G + E Y +GS +K A RD G Sbjct: 26745 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26800 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 +C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P Sbjct: 26801 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26858 Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 I W N PI + + V L I++A D G YT A+N GQ S +A + V Sbjct: 26859 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 LP+ +P+ + L+ D + GS + +VQ+S + + Sbjct: 26919 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26964 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 + + F Q +QE F E + + N ++ + ++ G Sbjct: 26965 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 27023 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779 P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL Sbjct: 27024 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 27083 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813 ++ VQ G Y + L N G S V++ +++ Sbjct: 27084 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27117 Score = 115 bits (287), Expect = 5e-25 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%) Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222 F +++ + EG F CK++G P P++ W K R+ E+ M L+ Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297 Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282 G+AS+ + + + +F K N I Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330 Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342 KL +E AA G+P + +P S++ S SPR+ ++P+ Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369 Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402 R+ P +P R PA PA PG ++ R Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408 Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 P F KP S + E QT +F +V G P PE WF +G + Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522 V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+ Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577 + EG ++ G P P I WL N P +Y + E G A L I + +D Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578 Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617 YT A N G+ C V V + + + ++P AP Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638 Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662 K P F + L+ L++ +++ G+P V WLH+G Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714 ++ + SL + D+G TC A N G T A L V++ Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758 Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744 H+G +P + P V G++ C + Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876 Query: 805 CQVSLMLQNSS--ARALPRGREP 825 +V L +Q L R EP Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899 Score = 113 bits (282), Expect = 2e-24 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 +K S RK E L + AP + +V G + V P EV W HNG Sbjct: 26048 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26107 Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682 E+QES D H + GT ++C Sbjct: 26108 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26167 Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718 + VFPE T T EA +S EV++Q T + H Sbjct: 26168 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26227 Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752 + ++KPRS+T G+S SC G+P PTV Sbjct: 26228 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q Sbjct: 26288 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346 Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848 + + ++ R + P +++ Sbjct: 26347 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26406 Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 L P + +L+ E +++ VL+ + T + +++ Q + Sbjct: 26407 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466 Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954 ++ L+E D + EI E + NLQ + K++ E+ K+ ++ D + Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526 Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983 S + +K K P P P P+P T D ++ Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586 Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015 + GGK KL + G SS+ L KA++ ++ Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26646 Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067 + Q + + P A E + A +E +K M AK E L + ASK EE+ Sbjct: 26647 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26703 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 KK + H T + SE T K + + EG++L+L+ ++ Sbjct: 26704 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26761 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W LNG L ++ GS +++I++A D G+ C++K G +C +T+ Sbjct: 26762 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247 + E+ SDA P I P Q Sbjct: 26822 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26838 Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 + G++V +++G W K I S ++ + S N L I A G Sbjct: 26839 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26898 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S Sbjct: 26899 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26958 Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423 + S++ + + + S + Q + E + + + G S +Q S++ Sbjct: 26959 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 27016 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447 G + PK E SD E +V Sbjct: 27017 AGIRGIPPKIEALPSDISIDEGKV 27040 Score = 112 bits (279), Expect = 5e-24 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99 +N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311 Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155 D G YT A+N G + +L VE A LG P TL R +P +R I Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369 Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179 P F K EGQ R Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429 Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238 F K+ GRP P+ W G + V +++G Q L I D G +T + N Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489 Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297 +G++S+S L+++ ++ FV + K N I + S+L+ A + N Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538 Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339 W NS P + ++E K + V Q Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592 Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395 T + ++ +PEP ++ P G R K A P P Q D+ Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453 K ++ P F+ K S +K F C ++ G P V W +G P Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698 Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502 + + + + G L A +RDSG +C A+N G S TL Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757 Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536 ++E L M + + V D V+EG+ +C Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817 Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594 V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G + Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877 Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + + +++ R +L AP +P + G +V + T + E Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929 Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694 V+ L I +ESE+ F++R + S E + E Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738 E + E+ + + E T P F + +S T G Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049 Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798 + G P P W ++G + + + ++V LV++ V + + N Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109 Query: 799 RVGECSCQVSLMLQ 812 GE S L++Q Sbjct: 2110 IAGETSSHAFLLVQ 2123 Score = 111 bits (278), Expect = 6e-24 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 +PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L Sbjct: 12593 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12651 Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355 I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+ Sbjct: 12652 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12711 Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE Sbjct: 12712 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12771 Query: 1415 PSQESELTTVGE--KPEEPKD 1433 P ++ P EPK+ Sbjct: 12772 PLTSPKMVAQFPFGVPSEPKN 12792 Score = 110 bits (275), Expect = 1e-23 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567 AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+ Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I + G Y+ A N GQ + +A + V K+E AP P F+Q Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168 Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713 ED+GTY+ A NS G + A L VQ Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 109 bits (272), Expect = 3e-23 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%) Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89 T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58 Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144 S L I AV + + G+Y+ +ATNGSG T EL V+ A Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PP F +L + V++G R ++TG P P V + + +Q S Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252 +S++ + L I +D G Y+ N G+A+ +AEL +QG Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207 Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + +A S R+T+ + + ++ + E +D AA + +P R PP + Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263 Query: 312 SQPQPP 317 P PP Sbjct: 264 RSPTPP 269 Score = 109 bits (272), Expect = 3e-23 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7456 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y + Sbjct: 7457 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7515 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426 E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T + Sbjct: 7516 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7575 Query: 1427 KPEEPKDEVEVSD 1439 P P +E SD Sbjct: 7576 DPPGPPTRLEPSD 7588 Score = 105 bits (262), Expect = 4e-22 Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%) Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 +F + +V E + F CEVS P V W + ++ + I++ ++ H L + Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 R D+G Y+ A + +L V S+ K+ VIE Q V++ Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121 Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 V V W +G I + + E + + I + D G YT +A Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 +R S L AP P LQ L + V G +SG Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P P++ W + F G +++L + E FPED YTCEA N G T A Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279 Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 L+V+ P D P + I+ + S GQ C ++G + +D K Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 K + F + Q ED + L + + P G Y + N VG+ S +L L+ Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388 Score = 104 bits (259), Expect = 9e-22 Identities = 102/419 (24%), Positives = 172/419 (41%), Gaps = 48/419 (11%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P+ + Q V+ + +F +SG P+P+++W+ E + + D + L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526 L++A D+ Y+C A N G + S +L VE V+ P+ + L+D Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311 Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583 EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370 Query: 584 LAENALGQVSCSAWVTVHEK--------KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 +A NA+GQVS +A +++ + K R+S VA S T ++K Sbjct: 3371 VASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIKSF 3430 Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695 GS VQV + I H +Q+++ H+ + ++ + C Sbjct: 3431 QGSSYEYEVQVFESVSQSSI--HTAASVQDTQ--------LCHTASLSQIAESTELSKEC 3480 Query: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL 755 A S GE P + VT G + C + D F V W Sbjct: 3481 -AKESTGEA----------------PKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWT 3523 Query: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814 +G A +++ + QN ++ L + VQ G Y ++ N GE + L ++ + Sbjct: 3524 HEG-AKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGA 3581 Score = 102 bits (253), Expect = 5e-21 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 +++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A Sbjct: 20571 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20630 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG Sbjct: 20631 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20690 Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 + + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP Sbjct: 20691 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20747 Query: 1417 QESEL 1421 + + Sbjct: 20748 ESDSV 20752 Score = 101 bits (252), Expect = 6e-21 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%) Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292 +PP + ++ E V+AG +V + G T W +I+ EH VE Sbjct: 11201 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11260 Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352 S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11320 Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411 DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G Sbjct: 11321 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11380 Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469 P +S T K P P + V+D E V + + ++ +Y +E R Sbjct: 11381 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11438 Query: 1470 LGSGKFGQV 1478 +GK+ +V Sbjct: 11439 EVTGKWVRV 11447 Score = 101 bits (252), Expect = 6e-21 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++ Sbjct: 16235 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16291 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL Sbjct: 16292 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16351 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16411 Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432 YG EP + + P+ PK Sbjct: 16412 YGVGEPLESEPVVAKNPFVVPDAPK 16436 Score = 101 bits (251), Expect = 8e-21 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%) Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302 F + VRAG S+ LF G T W K + S + +++ S LT+ + Sbjct: 22058 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22115 Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362 G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+ Sbjct: 22116 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22174 Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421 + Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E Sbjct: 22175 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22234 Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471 E+P P+ D V+ S +P+ D + QK SDF+ +E Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22293 Query: 1472 SGKFGQVFRLVEK 1484 V RLVEK Sbjct: 22294 KQLTFTVERLVEK 22306 Score = 100 bits (250), Expect = 1e-20 Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%) Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119 +V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG + Sbjct: 4463 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4519 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 +LTV A PV+ + K+ + V G + + Sbjct: 4520 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4547 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F+C+I P + W K + S + S+ + LEI D G YTC N Sbjct: 4548 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4607 Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294 G S +A L ++ G + R + E K + ++EV +V+ K + + + K Sbjct: 4608 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4664 Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354 + P PP P+P E ++ + R P+ + + +I L A +P Sbjct: 4665 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4718 Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414 +P A + P E P P T P ++ +AA + P++G Sbjct: 4719 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4777 Query: 415 KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441 E+ +P S K F ++ +P Sbjct: 4778 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4837 Query: 442 KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P A W +G+ + R+ D L ++ + D+G Y+C + + Sbjct: 4838 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4896 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 + L VE L V V ++ ++ V++GQ L C + + W +G+ + Sbjct: 4897 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4950 Query: 559 STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 GV L I DA D GTYT ENA + CS+ V V E Sbjct: 4951 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4997 Score = 100 bits (250), Expect = 1e-20 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 ++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L + Sbjct: 15160 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15219 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG Sbjct: 15220 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15279 Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 + + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP + Sbjct: 15280 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15339 Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471 + V P+ PK+ EV D P+ D + IN Y +E R Sbjct: 15340 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15389 Query: 1472 SGKFGQVFRLVEKKT 1486 K GQ + KKT Sbjct: 15390 -DKAGQRWIKCNKKT 15403 Score = 100 bits (249), Expect = 1e-20 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y Sbjct: 15854 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15913 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y + Sbjct: 15914 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15973 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 E D++ TW+ + AT T+ L EY+FR+ A N YG S Sbjct: 15974 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 16019 Score = 100 bits (248), Expect = 2e-20 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%) Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567 V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623 L I LPED G YT A N G CS + V Y L PV+ + +P Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362 Query: 624 -------------------------------------------------IFLQGLSDLKV 634 +F+ K Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 ++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 +T A N AG +LTV+ +P F+ K ++V G + + G+P P + Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541 Query: 753 HWLRD 757 WL++ Sbjct: 1542 VWLKN 1546 Score = 100 bits (248), Expect = 2e-20 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A++ S +L +V +PL FI P ++ + E AKFE V P+ Sbjct: 5513 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5563 Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114 W + Q IT RF L+ G + + + A +E + + E + SG Sbjct: 5564 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5622 Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144 + VT + F +L + KT F Sbjct: 5623 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5682 Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190 +++ I E P F KL E C+I+ P Sbjct: 5683 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5742 Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248 V W K ++PS + ++L + + D+G YTC G+ K S ++ Sbjct: 5743 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5799 Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287 S++ +++ F ET+ + D+ + I +E K+ S Sbjct: 5800 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5857 Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341 L NC Q GG AAN + K L KD TA +T Sbjct: 5858 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5913 Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395 S L+ +++P + + P E + R + G + Sbjct: 5914 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5963 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 +K + + +F + Q V+E T CEVS +V WF GT + Sbjct: 5964 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 6020 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 + + E+ D L + D TY+C A + + SC+ L V+ Sbjct: 6021 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 6070 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572 F L D V E + +C + ++ W +G I+ + + V L I Sbjct: 6071 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6129 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632 L +D Y+C A S +TV E+++ +F + L+++ Sbjct: 6130 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 6167 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 +V + + + +VS P EVIW EI E+ + G + L IQ ED G Sbjct: 6168 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6226 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 Y C +S RT + V E FISKP+++ G+ C+I+ + FP V Sbjct: 6227 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6277 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796 W RD K L + ++V+ + LV+K G Y +++ Sbjct: 6278 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6320 Score = 100 bits (248), Expect = 2e-20 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288 MPP I E +V G +V + K+ G T TW K ++ + H+ Sbjct: 9811 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9869 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348 ++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + + Sbjct: 9870 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9929 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407 TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A Sbjct: 9930 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9989 Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 N YG EP + +PE ++ V + D V ++T+N E+ D Sbjct: 9990 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 10038 Score = 99.8 bits (247), Expect = 2e-20 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%) Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343 E + +K PQR S P +P P E+ +++ ++KT+ Sbjct: 693 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750 Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403 T + V PR SP K P G + ++ +A + Sbjct: 751 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796 Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463 E S+ K ++ VK ++T R P P+ F + + E +EV Sbjct: 797 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852 Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523 ++ G + + R+ A+ + VE + P+ S LK+ Sbjct: 853 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580 VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G Sbjct: 907 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966 Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614 +TC A N G VS S ++ V EK+++ +E Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026 Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671 P +P AP F+ K+++G V QV GNP P V W +G + + + Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 ++ + L I F +D G YT N GE A L + ++ Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132 Score = 99.4 bits (246), Expect = 3e-20 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++ Sbjct: 17318 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17374 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351 + L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+ Sbjct: 17375 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17434 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410 W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y Sbjct: 17435 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17494 Query: 1411 GTSEPSQES 1419 G EP + + Sbjct: 17495 GVGEPLESA 17503 Score = 97.8 bits (242), Expect = 9e-20 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%) Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +E VK+ C++ + +V W+ + E YED G L + D GT Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25333 Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522 Y C N G+ S C T++ + + ++E P F+ L + Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25393 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576 G++ ++ P P +TW +GQ I+ + + G+ +L I + Sbjct: 25394 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25453 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 D YT +A N G+ SC A +TV L P P+F + L++ + + Sbjct: 25454 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25503 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695 G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y Sbjct: 25504 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25563 Query: 696 EAWNSAGEVRTQAVLTVQ 713 A N+AG QA L V+ Sbjct: 25564 TATNTAGSTSCQAHLQVE 25581 Score = 97.4 bits (241), Expect = 1e-19 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y Sbjct: 21270 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21329 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T++++N + + + + P P G +I++ S+ LSW +GG + YSI Sbjct: 21330 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21389 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P Sbjct: 21390 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21437 Score = 97.4 bits (241), Expect = 1e-19 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26128 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278 + DD G Y + N G+AS A L + G D + R + V E+T Sbjct: 26129 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26188 Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 +S K +EA++ + S + + S + ++++S ++ + Sbjct: 26189 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26245 Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396 +K +++ AAR+ +PR+ + GE + PT L V+S Sbjct: 26246 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26297 Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450 +A ++ + + + S S E V EN K E + I K V Sbjct: 26298 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26355 Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509 +P R + V +K+ R S S + + + + T +V+ L V Sbjct: 26356 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563 P + LK A + L C V + + +TW +G+ ++ + Sbjct: 26410 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466 Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609 G EL I + D G Y C G Q A+ ++HEK KS +K+ Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526 Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 ++P AP + + GL D V S V+ +G P P IW +G Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 I + + + L I + D+G YTC NSAG V + LT++ D Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26641 Score = 96.7 bits (239), Expect = 2e-19 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y + Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13120 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 + +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P Sbjct: 13121 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13168 Score = 96.7 bits (239), Expect = 2e-19 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%) Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64 K + I+KTS + + R + E AF + I EG + + G + V Sbjct: 26713 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26763 Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 W NG +T+ + G+ G+ +L I D G TC + G + +LT+ Sbjct: 26764 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821 Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183 SK L D APA ++P + EGQ F+C+ Sbjct: 26822 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26851 Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243 I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S Sbjct: 26852 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26911 Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301 +A L + L V + V+ + S SL+ +++S S+ + Sbjct: 26912 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26954 Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361 + S ++S E K S ++ Q ++ +SSS + Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26999 Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421 G+ + + E S + KA R IP PK E+ P Sbjct: 27000 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 27031 Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480 + E + + C +G P PEV W G + QE G + L ++ + + Sbjct: 27032 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 27091 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507 D G Y+ + N G S + + + + Sbjct: 27092 DGGLYTLSLGNEFGSDSATVNIHIRSI 27118 Score = 96.3 bits (238), Expect = 3e-19 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%) Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P T PP + + F + +R GE+ L G+ +G +W K + E + + Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346 + + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++ Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405 + +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+ Sbjct: 10623 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682 Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431 A N+YG S+P + V + P++P Sbjct: 10683 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10713 Score = 95.9 bits (237), Expect = 3e-19 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%) Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +G + + + K P P I D V GE + + T +W K Sbjct: 8061 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8177 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392 ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+ Sbjct: 8178 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8236 Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449 DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + + Sbjct: 8237 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8295 Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474 + + K+ + I E++ G+ Sbjct: 8296 KPPLYDGGSKIMGY--IIEKIAKGE 8318 Score = 95.9 bits (237), Expect = 3e-19 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%) Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561 ++A +E+ P ++ EG C + ++TW + ++ + T Sbjct: 25256 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25314 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608 E GVA L+++D D GTY C N G+ S A + V KK R+ Sbjct: 25315 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25374 Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667 ++ + L P + T P++ + G V V ++ +P P V W +G +I+ + Sbjct: 25375 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25429 Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720 + + FE + L I V +D YT A N GE +A LTV P D T + Sbjct: 25430 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25489 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F + GQSV ++G P PT+ W +DG+ L + + D + L Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 ++ P G Y + N G SCQ L ++ Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581 Score = 95.5 bits (236), Expect = 4e-19 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%) Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 ++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G Sbjct: 14085 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14144 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY Sbjct: 14145 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14203 Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q + Sbjct: 14204 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14260 Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 V P P ++ EVS+ V T T++ ++ V D Sbjct: 14261 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14293 Score = 94.7 bits (234), Expect = 7e-19 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S+ +F + G TW K I +EN+E+ + L I + G + Sbjct: 14483 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14540 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y + Sbjct: 14541 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14599 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E Sbjct: 14600 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14659 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478 P P D + + D + + + + K++ + +R GS ++ + Sbjct: 14660 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14709 Score = 94.7 bits (234), Expect = 7e-19 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++ Sbjct: 19481 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19537 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L Sbjct: 19538 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19597 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19657 Query: 1410 YGTSEP 1415 YG EP Sbjct: 19658 YGVGEP 19663 Score = 94.4 bits (233), Expect = 1e-18 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23210 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y + Sbjct: 23211 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23269 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E Sbjct: 23270 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23329 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P P ++EV D V TVT+ E+ + D Sbjct: 23330 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23356 Score = 94.0 bits (232), Expect = 1e-18 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19160 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y + Sbjct: 19161 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19219 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E Sbjct: 19220 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19277 Query: 1428 PEEP 1431 P P Sbjct: 19278 PFSP 19281 Score = 93.2 bits (230), Expect = 2e-18 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%) Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301 +AG + + + G +W K +K +++ H ++E +EN S + I + Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + H G Y++ +NK G + A + V+D P PP SDI S LSW DGG Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9636 Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 ++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + + Sbjct: 9637 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9696 Query: 1421 LTTVGEK--PEEPKDEVEV 1437 TT + P +P ++++ Sbjct: 9697 RTTARDPIYPPDPPIKLKI 9715 Score = 92.4 bits (228), Expect = 4e-18 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 + P F +L +K A FE R+ G P V W +G+P+ + R + G Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146 SL + D G TC ATN G + L V E S ++ P K L Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773 Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199 + ++ G + P V V EG+ RF C++TG PQP+V W Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 ++ S R V +G+ L+I D G N G +L IQ + RS Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891 Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318 +R + + E K+D ++K +R + Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951 Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378 SK + + T V K+ ++ + EE+K A Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 T PT +P +I + ++ PK + QSQ V + FR V Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 G P PE W+ G + R + + + L + DS + A N G+ S Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557 L V+ ++ +F+ L+D E P ++ W +G + Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172 Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 R + V L I D Y+C V V ++ ++ ++ Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218 Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672 A + F++ L D++V + + VS PE I W HN E++ + + Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269 Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694 R + +L +++V ED G Y+ Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291 Score = 92.4 bits (228), Expect = 4e-18 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290 P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++ Sbjct: 18400 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18456 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L + + G Y L + N G++ + + V+D+P PP G + + + L Sbjct: 18457 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18516 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N Sbjct: 18517 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18576 Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438 YG EP + +T KP P EVS Sbjct: 18577 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18606 Score = 92.4 bits (228), Expect = 4e-18 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 T + TV+ T + MP + I P AG VEL + G P +W Sbjct: 23418 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23471 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 +++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP Sbjct: 23472 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23531 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394 G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L Sbjct: 23532 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23591 Query: 1395 LPDHEYKFRVRAINVYG 1411 +EY FRV A N +G Sbjct: 23592 TEGNEYVFRVAATNRFG 23608 Score = 92.0 bits (227), Expect = 5e-18 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 +P+T P + +N+ + EG + E + GYP P VTW+R I S F + Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143 G L+I ED G++TC A N +G + L V+ S + V++ T R Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009 Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194 F S V T S+ E P F TK + EG F C++ G P+P V W Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069 Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 K VPL R VS +++ G L I DD G YT +V N G+ S SA L Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125 Score = 92.0 bits (227), Expect = 5e-18 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AGE V++ G P T TW K K + +EN+++ S LTI + G Y Sbjct: 20979 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 21038 Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I Sbjct: 21039 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21157 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474 P P ++ + D + + + + ++++ + ER G G+ Sbjct: 21158 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21201 Score = 91.7 bits (226), Expect = 6e-18 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y + Sbjct: 16996 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 17055 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 + D+ W + AT T+ V L EY+FR+ A N YG S Sbjct: 17056 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101 Score = 91.3 bits (225), Expect = 8e-18 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%) Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301 KV+AGE V + VTG W K I++ +V SE ++L+I A Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 +E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS Sbjct: 9164 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9222 Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418 + Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ + Sbjct: 9223 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9282 Query: 1419 SEL 1421 ++ Sbjct: 9283 DKV 9285 Score = 91.3 bits (225), Expect = 8e-18 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%) Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282 P P PP++I +Q ++ G+++ L + G TW K + Sbjct: 10899 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10958 Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342 + V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+ Sbjct: 10959 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 11015 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401 IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y Sbjct: 11016 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11075 Query: 1402 FRVRAINVYG 1411 FRV A N YG Sbjct: 11076 FRVAAENQYG 11085 Score = 91.3 bits (225), Expect = 8e-18 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%) Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PKA +PP+I + +KV RA ++ LF + G W R + + Sbjct: 15544 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15601 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 +E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++ Sbjct: 15602 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15660 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV Sbjct: 15661 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15720 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A N YG P++ +E E+P P Sbjct: 15721 LAENEYGIGLPAETAESVKASERPLPP 15747 Score = 90.5 bits (223), Expect = 1e-17 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%) Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 V AG + + V+G P T TW M R QE+ +E + S + I ++ H G Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10287 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10346 Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425 IE +S + W + T + VQ L+ Y FR+ A N G + SE + Sbjct: 10347 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10406 Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475 E PE P+D +EV EV TVT+ D Y +E RL G+ KF Sbjct: 10407 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10458 Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524 K T + + KE + +S +N + K C Sbjct: 10459 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10500 Score = 90.1 bits (222), Expect = 2e-17 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ LF + G W K +I+++ + V +S + L + + G Y Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16706 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y + Sbjct: 16707 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16765 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E Sbjct: 16766 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16825 Query: 1428 PEEP 1431 P+ P Sbjct: 16826 PQPP 16829 Score = 90.1 bits (222), Expect = 2e-17 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%) Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278 P P +++++P+ D++ + G V G + T PI C W K + I Sbjct: 23813 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23872 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G Sbjct: 23873 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23930 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397 DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L + Sbjct: 23931 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23990 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454 EY FRV A N +G S+P + E T PE P + EV D + + + Sbjct: 23991 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 24050 Query: 1455 NTEQKVSDFY 1464 + +V+ +Y Sbjct: 24051 DGGSRVTGYY 24060 Score = 89.4 bits (220), Expect = 3e-17 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679 AP F Q L + V++GS T +SG P PEV W +G I S + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122 Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799 + + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 800 VGECSCQVSLMLQ 812 VG + L++Q Sbjct: 182 VGRATSTAELLVQ 194 Score = 89.0 bits (219), Expect = 4e-17 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%) Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467 Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+ Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846 Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527 G HYL ++ ++ D+G TA N +G + L++++ F SVL+ Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900 Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V LQ V+ P + L + I + + E+ EL + Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958 Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618 + G Y + E L + W E+K + E + + Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018 Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 KP AP + + V GS V+V G P PE W NG +I+ S+ Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078 Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728 + + L I++V ED+ + +A N AGE + A L VQ T F + + Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135 Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758 V A ++ +PF V W +DG Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165 Score = 87.8 bits (216), Expect = 9e-17 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%) Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285 PK + P I + VRAG + LF V G TW K +++ + Sbjct: 12292 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12348 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+ Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12407 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV Sbjct: 12408 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12467 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A+N YG P+ + + EP Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEP 12494 Score = 87.8 bits (216), Expect = 9e-17 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%) Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 P P P I+ PE + +RAG ++ L+ V G P TW K + Sbjct: 13370 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13429 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 ++ + +++++ + L + G Y L +EN G ++ + + V+D P PP Sbjct: 13430 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13488 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397 +I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L Sbjct: 13489 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13548 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428 Y FRV A N YG +P + + + P Sbjct: 13549 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13579 Score = 87.8 bits (216), Expect = 9e-17 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%) Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I + +KV RA ++ LF + G W K + ++ ++E + + + Sbjct: 18799 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18856 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW Sbjct: 18857 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18915 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG Sbjct: 18916 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975 Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P++ +E V E P P V +V T TI E+ SD Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 19017 Score = 87.0 bits (214), Expect = 2e-16 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S + G TW R++ + ++ +++E N ++L+I + G Y Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17788 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I Sbjct: 17789 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17847 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 + +S K + +++ C TSF V++L Y FRV A N +G P + + E Sbjct: 17848 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17907 Query: 1428 PEEP 1431 P P Sbjct: 17908 PSPP 17911 Score = 87.0 bits (214), Expect = 2e-16 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 ++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y + Sbjct: 18078 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18137 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E D+ TW + AT T+ + L EY+FR+ A N YG S P Sbjct: 18138 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18185 Score = 85.5 bits (210), Expect = 5e-16 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472 P F QS V E T F +SG P PEV+WF +G + +++ G L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531 + +SG YS A+N GQ T E L E A P+F L+ V +G Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+ Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616 +G+ + +A + V E+ ++K++ ++ A Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211 Score = 85.5 bits (210), Expect = 5e-16 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+ Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I D G++T A N +G ++V LTVE AVE Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505 Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210 + P F KL V +KEG + TG P P + WLK + + P ++ + Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561 Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 G L+I D YT +N +G+ + +++++ Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602 Score = 84.0 bits (206), Expect = 1e-15 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%) Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 + G + +W K + + VE+S + L + ++ G YT+ ++N G+++ Sbjct: 13701 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 +++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W Sbjct: 13761 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13820 Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 A+ + T+F V L EY FRV A N YG E Sbjct: 13821 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13855 Score = 83.6 bits (205), Expect = 2e-15 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%) Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I FP VRAG ++++ ++G T + ++ + E + Sbjct: 20168 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20227 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 + + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W Sbjct: 20228 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20287 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G Sbjct: 20288 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20347 Query: 1413 SE 1414 S+ Sbjct: 20348 SD 20349 Score = 83.2 bits (204), Expect = 2e-15 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%) Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 P I++F + +++GES+ + V G TW K +I++ +M++ + + Sbjct: 21650 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21709 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W Sbjct: 21710 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21769 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G Sbjct: 21770 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21829 Query: 1413 SEP 1415 P Sbjct: 21830 GRP 21832 Score = 82.8 bits (203), Expect = 3e-15 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%) Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938 H EE+ QQ + +++ ++S ++E + PA + + + VKP+ + Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726 Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997 SE K + + S + K T V P+ A+P F K +P Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783 Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055 A + K LS + + + + A T+KP AE L A Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840 Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095 + KS + E+KK+V + GTT E+R E Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894 Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155 T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + + Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213 I +A ED G + C A N+AG SC V V + E T E + K + Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +D ++ ++ A P A P I P QK+ G SV +V G W K Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071 Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325 + KV N + G KL I + G YT++V NK G A +L Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125 Score = 82.4 bits (202), Expect = 4e-15 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%) Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457 ++G++ + K + +P Q+V E V+ +VS + E W +G V+ Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352 Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517 + + + D SH L + D+G YS T L S + +V +V + P Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404 Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574 LKD VIEG VL+C V V + W LN + I+ ++ + L I Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462 Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634 D G Y + +G+V + ++V + K ++GL DL Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694 + V V++S + +V+W EI+ S + E G + L + + +D G YT Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753 AGE T LTV ISKP T + Q + C +A +P Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605 Query: 754 WLRDGKAL 761 WLRDGK L Sbjct: 2606 WLRDGKHL 2613 Score = 82.4 bits (202), Expect = 4e-15 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%) Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144 D E R++ + AP K QD+ V GK L + + P A W + L T Sbjct: 6682 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6741 Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204 +++ S + +K D+G YK V +N G+AE + V D P Sbjct: 6742 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6786 Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264 PV E T + + ++ + G S ++ G V Sbjct: 6787 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6823 Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322 + I TW+ + + E + G + + + G + +N + +R Sbjct: 6824 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6883 Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W Sbjct: 6884 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6936 Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 T R+ S V D++ EY FRVRA N G +PS + V + E P V ++ Sbjct: 6937 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6996 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493 D+ + V + + I ER GK + +LV + T KV K Sbjct: 6997 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 7056 Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516 + SA+ K + I+ L Sbjct: 7057 YLYRVSAENKAGVSDPSEILGPL 7079 Score = 82.4 bits (202), Expect = 4e-15 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG S + G W K ++ + V+ +++ + LTI A + G Y Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19950 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I Sbjct: 19951 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 20009 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E +++ K W + C S+ V +L Y FRV N +G P++ E + EK Sbjct: 20010 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20069 Query: 1428 PEEPK 1432 P P+ Sbjct: 20070 PSPPE 20074 Score = 82.4 bits (202), Expect = 4e-15 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G Sbjct: 24602 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24661 Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 EI + + ++ +G H L I V +D Y A N G V A L V+ P Sbjct: 24662 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24721 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L Sbjct: 24722 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24780 Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801 V V+ AG Y + KNR G Sbjct: 24781 VFPNGVERKDAGFYVVCAKNRFG 24803 Score = 82.0 bits (201), Expect = 5e-15 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%) Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78 R D+M L E P F LP N G +F + +PEP VTW+++GQ I G + Sbjct: 25374 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25433 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + + +G + L I++V +D +YT A N G +LTV L P Sbjct: 25434 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25486 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 TL P F L +EGQ F +++G P P + W K Sbjct: 25487 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527 Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257 PL + + E L I +D G Y N +G S A L ++ L Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587 Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290 + F + + V+K++ + L E+ Sbjct: 25588 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25619 Score = 81.6 bits (200), Expect = 7e-15 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306 V+AG+++ L V G W K + + S +K++ + SK ++ A++ G Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11967 Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y Sbjct: 11968 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 12026 Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423 +E ++ W AT + V L+ +EY FRVRA N GT P++ + T Sbjct: 12027 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12086 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464 +KP P D EV+ ++E V + + + ++ ++ Sbjct: 12087 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12126 Score = 81.6 bits (200), Expect = 7e-15 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 + ED G YTC A N GEV T + L +Q P + K + A +G ++ + Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24344 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800 G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N Sbjct: 24345 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403 Query: 801 GECSCQVSLMLQN 813 G + + +Q+ Sbjct: 24404 GTVDAILDVEIQD 24416 Score = 81.3 bits (199), Expect = 9e-15 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%) Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L + Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 L T D+ YSC + + + +L V F L+D V E L+ Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241 Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 C V + W N ++ T G L ++D ED G Y+ + + Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 KK++ K + KP LQGLSD KV +G V + V+VS Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338 Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707 E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397 Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 +V I+ + V G ++ C ++ +V W + + + K Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444 Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 + + LV+ + G Y++++ RV E +C +S+ Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484 Score = 80.9 bits (198), Expect = 1e-14 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 + E ++ F E+S P W L+G + R + E+ + G +L L K + +G Sbjct: 5103 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 5160 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 A NA + L V E+ F+ LKD V E + +C + T Sbjct: 5161 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5209 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601 + W I+ + + HI D+ +D G YT E + S +VT Sbjct: 5210 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5267 Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 K F+ L D V +G T ++S + V+W N Sbjct: 5268 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5306 Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721 ++ S G H L ++EV +D + E+ + A L V E P Sbjct: 5307 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5358 Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781 +F K TA + + C ++ D V W +DG+ + + + + L + Sbjct: 5359 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5415 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837 KK G+Y C C N + A L + +P ++ G Sbjct: 5416 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5466 Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889 + D +G W +GQ D E + K + T + + +A Sbjct: 5467 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5522 Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949 + L ++L + LS D+K ++ F + R+ PKT R + Q Sbjct: 5523 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5572 Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007 ++ D R L K GT + V + A F + + +G E + K Sbjct: 5573 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5626 Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067 + K ++ + + V + +K N + T + + + + + S + ++L Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5685 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 D + + + G + K + +G P F KLQD E +++LQC++S A Sbjct: 5686 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5741 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ + Sbjct: 5742 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5797 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 +D E+K RP S+ V+ TE+ Sbjct: 5798 EDR---------EIKLVRPLHSV-EVMETET 5818 Score = 80.9 bits (198), Expect = 1e-14 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PPKA + ++ + +RAG + L V G W K K++ E + ++ + Sbjct: 22738 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + I + G YTL V+N G++ V + V+D P P G S + TL Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22854 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N Sbjct: 22855 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22914 Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433 YG SEP T+ P P++ Sbjct: 22915 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22943 Score = 79.7 bits (195), Expect = 2e-14 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AG+++++ V G T TW K + +++++ + E + + L I + G Y Sbjct: 14773 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14832 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 L N +G + + V D P PP G ++ S +T SW DGG + +Y +E Sbjct: 14833 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14892 Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411 + + + TW ELA T T++ L EY+FRV+A N YG Sbjct: 14893 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14935 Score = 79.3 bits (194), Expect = 3e-14 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Query: 1789 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848 EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD + Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284 Query: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336 Score = 79.3 bits (194), Expect = 3e-14 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%) Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80 P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079 Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140 LVI V ED +A N +G L V+ AKQL Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127 Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199 F +L VV KE M F C+ T P +V W K + Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 + + + + L I ++ D Y+C++V +A+L ++G A Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222 Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312 FV+E + E+ ++S E+ + +E + K + +RG + Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282 Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363 + E K +CK + P +LQ S + VQ E + GV Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341 Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420 G+E +P+ + L +D+ + A IP G S S Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400 Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 +K+ ++ C+VS V W+L + + + ++ L + Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 + D G Y G++ + L VE++ ++ L+D E Q+ V + Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508 Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592 + + + + W + I+ + + + +L + + + +D G YT A G+ Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563 Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652 S +TV A SKP L+D V + + +V+ NP Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602 Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + WL +G + + + E G + L I +D G YT + S +T A L V Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658 Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 + I K +++T + Q + + + V W+++G L Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701 Score = 79.0 bits (193), Expect = 4e-14 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471 P+F ++ + V+F ++ P+P V W+ G ++ + + D G + Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528 L + T D Y+ A N G+ SC L V + P F +L + EG Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25504 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584 Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y Sbjct: 25505 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25564 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611 A N G SC A + V E+ +K E+ Sbjct: 25565 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25590 Score = 78.6 bits (192), Expect = 6e-14 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%) Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276 +P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K Sbjct: 8359 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8416 Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310 ++QE E + ++NS+ G S+L + + + G Y + Sbjct: 8417 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8476 Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370 VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E Sbjct: 8477 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8535 Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 D + W + +T R ++V L+ EY FRVRA N +G P L V + Sbjct: 8536 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8593 Query: 1428 PEEPKD 1433 P P D Sbjct: 8594 PFGPPD 8599 Score = 78.2 bits (191), Expect = 7e-14 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%) Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94 I P +++ + EG A E +V V W+ N + I R + ++GT LVI+ Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459 Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154 H D G Y G + L+VE Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487 Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214 K L + E Q F +++ V W + ++PS++ + Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272 + L + + +DD G YT +G+ S +L++ G + ++ +T A + + Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594 Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329 EV N SK L + + N S G A K+ + K S Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654 Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378 + + ++KT ++T+ + P G+ GV+ S E+ Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 + + + + V R + + K KP+ EN TV F VS Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P V WF + ++ + + + H L L D+G Y+ GQL C Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 L VE L + + +K+ V E + +C V VP + WL NG I+ + Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879 Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 + + +L I + ED YT + N QVS + VT Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921 Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674 PI + L D+ + +T V V+ WL NG EI+ ++ + Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973 Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 HSL I+ V D YT AG+ + A L V+ H F + + Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 + + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y + Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083 Query: 795 LLKNRV 800 + V Sbjct: 3084 VAGGNV 3089 Score = 78.2 bits (191), Expect = 7e-14 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%) Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 P T A + P + F + +V + + TG T TW K ++ + +K Sbjct: 7078 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7137 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 ++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI Sbjct: 7138 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7196 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404 S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V Sbjct: 7197 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7256 Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433 A N G EP+ E ++T P+ P++ Sbjct: 7257 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7288 Score = 78.2 bits (191), Expect = 7e-14 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA ++L V ++ +L + D + I L K + F + + + ++ Sbjct: 22241 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22300 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 E+ + + ++ AKNDAG +E P+ + V+ Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22332 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +K+ T + Q+I +AG + ++G TW + Sbjct: 22333 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22382 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337 ++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G Sbjct: 22383 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22442 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396 S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L Sbjct: 22443 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 EY FRV + N +G S+P + + + + E P P Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22535 Score = 77.4 bits (189), Expect = 1e-13 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%) Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072 Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509 G P+ + + G L + D+G Y+ N G+ S S +L +E Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567 + S +L V FV + V G P + + + ++ +A+ Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625 + ++ + + + E + ++ T E+ + + + + ++ S+ F Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247 Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683 + + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306 Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732 V PED G YT A N G L V+ P +I PRSV+ Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366 Query: 733 S 733 S Sbjct: 1367 S 1367 Score = 77.0 bits (188), Expect = 2e-13 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI Sbjct: 16925 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16984 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y N GQ S ++ D P + K P Sbjct: 16985 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 17027 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 D + + PP QI + ++ T W Sbjct: 17028 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17071 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332 + + +KV + G++ + + EN+ G A + +V +P Sbjct: 17072 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17119 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385 PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT Sbjct: 17120 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17173 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 T F Q+L EY+FRV A N+ G + S+ SE + + P Sbjct: 17174 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17219 Score = 76.6 bits (187), Expect = 2e-13 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+ Sbjct: 6520 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6578 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206 +D Y C ++ +A + + V+ +AP ++ E+ + Sbjct: 6579 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6638 Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241 ++++ V G + + K + + A P+I Sbjct: 6639 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6698 Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301 +D V G+ + + W K + + ++ + + IL A+ Sbjct: 6699 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6755 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS Sbjct: 6756 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6814 Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418 + Y +E D KTW LAT R+ S F V L EY FRV A N GT EP + Sbjct: 6815 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6873 Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441 K + P + V+ D Sbjct: 6874 DNPVEARSKYDVPGPPLNVTITD 6896 Score = 76.3 bits (186), Expect = 3e-13 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%) Query: 1772 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1830 S TG+ E L E V++ E P P ++++ V+EG + +C Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918 Query: 1831 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977 Query: 1891 ATCTAELIVETMEEGEGE 1908 + + L V+ EE E E Sbjct: 978 VSTSCYLAVQVSEEFEKE 995 Score = 75.9 bits (185), Expect = 4e-13 Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678 K P+ L D +G V +T ++ EV W + E F Q + Sbjct: 4431 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4488 Query: 679 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737 +L I +V ED G Y CEA N +G+ T A LTV + P K + +LG Sbjct: 4489 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4545 Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797 +C I P W + G+ + ++ + ++ + +L + + Q G+Y Sbjct: 4546 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4604 Query: 798 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 N G SC +L + R L R+P E++ S+ Sbjct: 4605 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4651 Query: 854 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913 P + +E + E V K+ + + + EV + R+ +K+ T + Sbjct: 4652 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4704 Query: 914 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970 IP + + + +V KP V E + +P V V+ KK +K P E Sbjct: 4705 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4761 Query: 971 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027 P P + G KK P+ + + E P + + PLK V Sbjct: 4762 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4814 Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073 K + +G++ E L A K N++ + K D K+ Sbjct: 4815 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4874 Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124 + C + G+ T K + K ++V V +G+ L L C+++ + Sbjct: 4875 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4934 Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183 ++W +GK ++ I+ G + +++I A D G Y +N A ECS Sbjct: 4935 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4991 Query: 1184 QVTV 1187 V V Sbjct: 4992 CVKV 4995 Score = 75.9 bits (185), Expect = 4e-13 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%) Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105 N++P ++LK +E + D + + + +A G ++ + SE+ P + Sbjct: 8030 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8089 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165 D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D Sbjct: 8090 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8149 Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225 G+Y +N G A S V V P ++K+ SD T Sbjct: 8150 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8191 Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PP+ G PI ++ R++ ++ Sbjct: 8192 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8223 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343 V + EN T+ + + NK+G + N + P P P ++ Sbjct: 8224 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8283 Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395 + ++T++W YDGGS + Y IE + WK C ++ + L Sbjct: 8284 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8340 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442 EY+FRVRA N G SEPS+ + T + + PK +EV DE Sbjct: 8341 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8391 Score = 73.9 bits (180), Expect = 1e-12 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VKE Q V F CEV+ + WF + I + +D + L + A D Sbjct: 6346 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6403 Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 Y+ + +N +G+ + + L VE + V P LKD +E + C V V Sbjct: 6404 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6458 Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W NG+ + + H I+D D G Y VT Sbjct: 6459 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6502 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 + KS +E L+ AP++ F++ L D V + + Q+S V W NG Sbjct: 6503 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6554 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719 EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P + Sbjct: 6555 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6610 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 +P P+ + + G V+ + D V WLR+ + + H +++ + L Sbjct: 6611 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6663 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808 + ++P G+Y + K++ +++ Sbjct: 6664 QICDIKPRDQGEYRFIAKDKEARAKLELA 6692 Score = 73.9 bits (180), Expect = 1e-12 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V+V G L + +S P + + +G LK T ++++++++ D G Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224 Y+ A N +G + + V D P P V+ TE T+K Sbjct: 20241 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20286 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P PK + + I+ ++ S ++ +V+ T + T MK K E+ Sbjct: 20287 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20336 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344 +EN + + + S V L P PP+ TP +++ Sbjct: 20337 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20377 Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402 S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F Sbjct: 20378 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20437 Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 RV A N G +PS SE + E P++ V ++D + + ++ + K++ Sbjct: 20438 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20496 Query: 1463 FYDIEER 1469 Y +E R Sbjct: 20497 -YIVERR 20502 Score = 73.6 bits (179), Expect = 2e-12 Identities = 33/91 (36%), Positives = 56/91 (61%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++D +D Y CKA N LGE+TC AEL+V Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857 Score = 73.2 bits (178), Expect = 2e-12 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328 R+++ ++ +++ G+ L + ++ + + EN+ G S + T + Sbjct: 23962 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 24021 Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386 + P+PP+ P D+ SS++LSW DGGS V Y IE +++ W + Sbjct: 24022 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24081 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437 T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+ Sbjct: 24082 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24134 Score = 72.4 bits (176), Expect = 4e-12 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%) Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++ Sbjct: 8793 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8848 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347 N S+L I A ++ G Y + N GS+ A + V D P P R Sbjct: 8849 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8908 Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407 L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A Sbjct: 8909 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8967 Query: 1408 NVYGTSEPSQESELTTV 1424 N +G P + + V Sbjct: 8968 NKFGCGPPVEIGPILAV 8984 Score = 71.6 bits (174), Expect = 7e-12 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 +D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T Sbjct: 20859 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20917 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+ Sbjct: 20918 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20971 Score = 71.2 bits (173), Expect = 9e-12 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%) Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324 P T W++ K + +V+ N K + +L EN G + + Sbjct: 7619 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7667 Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 + + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W Sbjct: 7668 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7727 Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437 +A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV Sbjct: 7728 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7787 Score = 70.9 bits (172), Expect = 1e-11 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538 Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P + W +N I + ++ G +G +L I + +D YT A N +G Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597 Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161 ++ VE FA+ + + G +AP +E +G + P Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657 Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 F KL + +K F C++T G P V WL PL+ + R+ + + G L+ Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 D G+ TC N G SA L ++ +S V E++ Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759 Score = 70.9 bits (172), Expect = 1e-11 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 SE +GT P F +++ + ++ G L V P I W NG L + +G Sbjct: 3642 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3701 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 S+ I ED G Y C+A ND G+ CS + + N+K K Sbjct: 3702 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3747 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 TE+++ V K P PP ++ + + G V G T T Sbjct: 3748 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3799 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329 W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+ Sbjct: 3800 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3859 Query: 1330 KPDPPAGTPC 1339 + TPC Sbjct: 3860 EDTDMTDTPC 3869 Score = 70.9 bits (172), Expect = 1e-11 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21327 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y + N C++ V P + T P K + P Sbjct: 21328 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21358 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283 I+F E + +SV L V G ITC ++ R+ Q + Sbjct: 21359 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21400 Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337 M + + K+ L E+ + + EN+ G Q V+ +V K P PP G Sbjct: 21401 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21457 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395 P ++ S ++L+W YDGGS V + +E + + W+++ T + L+ Sbjct: 21458 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21517 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455 +Y+FRV A N G S PS S+ T+ P +P + D V T+T+ Sbjct: 21518 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21569 Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475 + D Y IE+R G+ ++ Sbjct: 21570 WNPPLRDGGSKIVGYSIEKRQGNERW 21595 Score = 70.5 bits (171), Expect = 2e-11 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A + I+ L+V +D F +P +++ + E A+FE + E Sbjct: 5159 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5207 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W + I S +F + + LVI+ +D G YT E Sbjct: 5208 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5252 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 VEG K R + KF + L VKEG+ F Sbjct: 5253 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5289 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C+++ + V W K + L S V +S + LE+ V DD+ V + Sbjct: 5290 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5344 Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283 S +A+L + D + + A D V K+V K+ Sbjct: 5345 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5404 Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337 K D L K K +G G+ AN + R K+E P + V Sbjct: 5405 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5459 Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397 + I L V + + G + + E Q G+ + +V + Sbjct: 5460 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5518 Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456 AAN + + P P S +V E KF CEVS PK W L+GT Sbjct: 5519 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5575 Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516 + E+ +D H + + A D Y A + +L + + F Sbjct: 5576 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5626 Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576 + LKD E + V + + R+ W N Q + RS + +QD Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5677 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 T+ L+ + Q+ A SE L V P F L D ++ Sbjct: 5678 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5726 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 +V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+ Sbjct: 5727 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5785 Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 G +T L +++ + + SV ++ I+ D +W Sbjct: 5786 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5836 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781 G+AL + T E+ + + +LVL Sbjct: 5837 KGEALLQ-TPDCEIKEEGKIHSLVL 5860 Score = 70.5 bits (171), Expect = 2e-11 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L + V G K+ L V+ P I WT LK K I + +V+I + Sbjct: 7392 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7451 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y A N G+A +V V D P PP +D T + Sbjct: 7452 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7493 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 PP+ +I + +++ E W K ++++ Sbjct: 7494 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7537 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339 K T L +E+ + + EN G Q + +T + DPP G P Sbjct: 7538 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7584 Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396 SDI ++TL+W DGGS + Y +E D W + T++ V+ L Sbjct: 7585 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7644 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 +Y+FRV A N+ G +PS+ +E + + + P Sbjct: 7645 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7679 Score = 70.1 bits (170), Expect = 2e-11 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1866 P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L I V + +Y+ KA N G+AT TAEL+V+ Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98 Score = 69.3 bits (168), Expect = 3e-11 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%) Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271 ESD V + P P TP A+ + + V G S + + + + W Sbjct: 17105 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17164 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 K K I K +N E G + + + EN +G +A N Sbjct: 17165 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17213 Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387 DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T Sbjct: 17214 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17273 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438 F V L D Y+FRV A N G S+PS + T ++ E P +D + V+ Sbjct: 17274 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17333 Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495 + E D + T + + +IEE F+ L+ K ++ G++ Sbjct: 17334 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17393 Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554 +A + ++ + +++ P+ VQ EK ++ + GG + E Sbjct: 17394 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17453 Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598 E + E + +++ EG EY+ + IM VNK G Sbjct: 17454 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17495 Score = 69.3 bits (168), Expect = 3e-11 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357 GC Y + EN G ++ DP P P D +++T++W + Sbjct: 19745 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19804 Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS Sbjct: 19805 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19864 Query: 1417 QESELTTVGEKPEEPKDEVE 1436 S+ E+ EEP +++ Sbjct: 19865 DSSDPQIAKEREEEPLFDID 19884 Score = 69.3 bits (168), Expect = 3e-11 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%) Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310 E S ++EVT + E + + + A + + S+ + R SP + Sbjct: 25924 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25983 Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368 S+PQP E + ++ + SP TP + PR+P SP Sbjct: 25984 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 26018 Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423 ER R A F +R + + K + R+ + Q+ P+ + +S Sbjct: 26019 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 26078 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 V Q +F V P EV W+ G ++ + I +G L +L T DSG Sbjct: 26079 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 26137 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542 TY +N +G+ S TL V G D+ S R V Sbjct: 26138 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 26175 Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596 PR + + YA S+ EA + ++ + E + + +A ++ +A Sbjct: 26176 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26235 Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654 ++ EK ++RK + L A L + V +G + G P P V Sbjct: 26236 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287 Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714 WL G + S + + I V D G Y+ NS G+ + LT+Q+ Sbjct: 26288 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26347 Score = 69.3 bits (168), Expect = 3e-11 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L AP L R+ + G +F V+ P +V W+ NG + + G Sbjct: 26065 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26123 Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121 +L I H +D G Y T + T G R V EL Sbjct: 26124 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26183 Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157 T ++A K+ + S ++ + + ETR S+ Sbjct: 26184 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26242 Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 + TK + V EG+ RFSC G P P VTWL+ L SAR Sbjct: 26243 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26302 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267 V+ EI V D G Y+ +V N GK L+IQ ++ V E KA Sbjct: 26303 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26355 Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327 S R V S E ++ S EA K SP+ P P + + E + Sbjct: 26356 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26406 Query: 328 SPRTAP 333 P +AP Sbjct: 26407 LPVSAP 26412 Score = 68.9 bits (167), Expect = 4e-11 Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%) Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502 EV W+ E V E + +D ++ L + K T D G Y C A N G+ + S L Sbjct: 4463 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4521 Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562 V V AP ++ V G C ++ P R W G+ I Y C Sbjct: 4522 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4576 Query: 563 AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618 ++ L I D G YTC A N G VSC+A +TV +K LLP Sbjct: 4577 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4636 Query: 619 KPTAPIFLQGL 629 +P + L+ + Sbjct: 4637 EPKEEVVLKSV 4647 Score = 68.9 bits (167), Expect = 4e-11 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%) Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 P KL V V G + L+ V P + WT + T+ + + Sbjct: 11896 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11955 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213 S+ KA D G Y A N AG V V D P N K ++ S R Sbjct: 11956 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 12007 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 TV P P+ + I++ E +++ W Sbjct: 12008 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 12040 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330 + + G+ +T L E+ + + ENK+G+ + V+ K Sbjct: 12041 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12088 Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 PDPP T + + +T+ W YDGG ++ Y +E + + W + + Sbjct: 12089 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12144 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 VQ+LLPDHEY+FRV+A N G EPS S V + P EP Sbjct: 12145 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12191 Score = 68.6 bits (166), Expect = 6e-11 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19149 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++A ED G Y+ N AG + V D P PP Sbjct: 19150 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19191 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 + + PP+ QI + ++K + + TW + Sbjct: 19192 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19235 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333 + + +K+ GS+ + + EN+ G + VV + P Sbjct: 19236 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19283 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386 P GTP S++ ++W DGGS V Y +E +W ANK Sbjct: 19284 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19338 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446 T V L Y++RV A N+ G + S+ E P +P + EV++ K Sbjct: 19339 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19397 Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475 + + + K++ + L G++ Sbjct: 19398 LKWSKPHYDGGAKITGYIVERRELPDGRW 19426 Score = 68.6 bits (166), Expect = 6e-11 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+ Sbjct: 26822 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26881 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194 ++ S+ I A D G Y AKN GQ + + V + P+ E Sbjct: 26882 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26941 Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235 ++++ +M + + ++S + + + + K A + + Sbjct: 26942 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 27001 Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 +PP+I P D + G+ + + TG TW Sbjct: 27002 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 27061 Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ + Sbjct: 27062 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115 Score = 68.2 bits (165), Expect = 7e-11 Identities = 86/356 (24%), Positives = 138/356 (38%), Gaps = 82/356 (23%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154 P Q+LQ V V GK +S P I W + L T KF+ QE +L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + +A PED +Y C AKND G A S ++V+ PE+ S P +P Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP II +D G+ +V+GT + +W Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV-VDKPDP 1333 K+I+ S ++ E+ +L I A E G YT + N +G + NL++ V D Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDR 3394 Query: 1334 PAGTPCASDIRSSSLT--------------------LSWYGSSYDGGSAVQSYSIEIWDS 1373 + D+R S+ + S+ GSSY+ Y +++++S Sbjct: 3395 QSS---GKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSSYE-------YEVQVFES 3444 Query: 1374 ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429 ++ + T+ +VQD H + ++E S+E + GE P+ Sbjct: 3445 VSQ------SSIHTAASVQDTQLCHTASLS----QIAESTELSKECAKESTGEAPK 3490 Score = 67.4 bits (163), Expect = 1e-10 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%) Query: 1788 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198 Score = 67.0 bits (162), Expect = 2e-10 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 ++ + V G + + P T WT +G +KT + + + ++I+ L Sbjct: 11212 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11271 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y+ N AG + +TV D P P + + T T+ Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11319 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P P I E Q R + +G V+ Sbjct: 11320 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11350 Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336 +GS T L GC + + ENK+G + V K P P G Sbjct: 11351 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11403 Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390 P +DI ++ T+SW DGGS + Y +E W NKT F Sbjct: 11404 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11458 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 V L + Y+FRV A N+ G S+PS S+ Sbjct: 11459 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11488 Score = 67.0 bits (162), Expect = 2e-10 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224 A+N +G + ++ V D P + K +M S R S P L G+E + Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13121 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 K P A +V+ T PIT ++ K I+ E+ Sbjct: 13122 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13154 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340 + + ENK G + K DPP P Sbjct: 13155 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13191 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 S+I +T+SW + DGGS + Y +E ++ W ++ + L Sbjct: 13192 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13251 Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420 EY+FRV AIN G +PS S+ Sbjct: 13252 EYEFRVTAINKAGPGKPSDASK 13273 Score = 66.6 bits (161), Expect = 2e-10 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%) Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134 G +D S+ Q ++ L D+ K L+++ S P ++W+ Sbjct: 19859 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19918 Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 L+T ++ + S S++IE A D G Y +N A + V V D P Sbjct: 19919 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19974 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254 PP T D T + A + + PE+ Sbjct: 19975 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19999 Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312 G P+ ++ R + S+ V + N ++L+ + Y V Sbjct: 20000 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 20048 Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E Sbjct: 20049 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20107 Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429 + K W + A +ST V L + EY FRV A N G S+P + + E+ E Sbjct: 20108 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20167 Query: 1430 EPKDEVE 1436 P+ +++ Sbjct: 20168 PPEIDMK 20174 Score = 65.9 bits (159), Expect = 4e-10 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8867 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y A N G + +V V D P P L PV+ T + Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8913 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P+ + + II+ +D K+ T QPI E+E K Sbjct: 8914 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8949 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342 + +T L QE+ + ++ +NK G ++ + VD PP ++ Sbjct: 8950 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 9000 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400 S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y Sbjct: 9001 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 9060 Query: 1401 KFRVRAINVYGTSEPS 1416 +FRV+A+N G SEPS Sbjct: 9061 EFRVKAVNEIGESEPS 9076 Score = 65.9 bits (159), Expect = 4e-10 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15230 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A N G A+ V V D P P V S+ V P Sbjct: 15231 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15277 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I+Q E ++ W ++Q ++ Sbjct: 15278 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15308 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346 K+T L E+ + ++ NK G + + V+ PDPP P + I Sbjct: 15309 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15364 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+ Sbjct: 15365 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15424 Query: 1405 RAINVYGTSEPSQES 1419 A N G S PS S Sbjct: 15425 MAENAAGISAPSPTS 15439 Score = 65.9 bits (159), Expect = 4e-10 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW + Sbjct: 15711 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15769 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q Sbjct: 15770 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15829 Query: 1418 ES 1419 S Sbjct: 15830 LS 15831 Score = 65.9 bits (159), Expect = 4e-10 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T Sbjct: 23037 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23095 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K Sbjct: 23096 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23149 Score = 65.5 bits (158), Expect = 5e-10 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89 +AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24680 Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149 L+I +V ++D Y ATN G+ T L VE L Sbjct: 24681 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24722 Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 PK +G V G++ +G+P P +TW KG + + V Sbjct: 24723 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24771 Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268 L +GV + D G Y N G + EL + + R Sbjct: 24772 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24825 Query: 269 SDVRKEVTNVISKESKLD 286 SDV ++ N+ E D Sbjct: 24826 SDVSRDSVNLTWTEPASD 24843 Score = 64.7 bits (156), Expect = 8e-10 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ K + G+ L ++ V P I W +G+ LK T + + + + + I Sbjct: 18007 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 18066 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y A N AG A + V V + P PPV Sbjct: 18067 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18108 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D + PP QI + +++ T TW Sbjct: 18109 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18152 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331 + + +K+ + G++ + + EN+ G + V+ +P Sbjct: 18153 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18200 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389 PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F Sbjct: 18201 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18259 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 L EY+F+V A N+ G +PS+ SE + + P Sbjct: 18260 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18301 Score = 64.7 bits (156), Expect = 8e-10 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%) Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68 S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R Sbjct: 26233 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26291 Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126 GQ +++ R + + TF I +V D G Y+ N G ++ LT++ + Sbjct: 26292 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26349 Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157 K + P K+ R +P ET+P+ + Sbjct: 26350 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214 PPK L KE + + +C + +VTW K L+ + +G Sbjct: 26410 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26467 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 L+I+ + + D G Y C + G + + + Q S + + ++ SD + Sbjct: 26468 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26527 Query: 275 VTNVISK 281 + V K Sbjct: 26528 ESTVTRK 26534 Score = 64.3 bits (155), Expect = 1e-09 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G+++ + +V G TW K K + + + + +L I A + G Y Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11674 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +N G Q + V+D+P P +++ + T+SW +GGS + ++ + Sbjct: 11675 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11733 Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425 E K W +A+ + +LL ++EY FRV A N G P+ E++ + Sbjct: 11734 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11792 Query: 1426 -EKPEEPKD 1433 ++P EP++ Sbjct: 11793 IDRPGEPEN 11801 Score = 64.3 bits (155), Expect = 1e-09 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%) Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269 G +S+ V + P P PP PP I+ D SV L K TG PIT Sbjct: 13856 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13904 Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++F R + K K+T L E+ + ++ N G + + Sbjct: 13905 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13962 Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 V DP P G P +I +S+TL W YDGG + Y +E D +K+W + Sbjct: 13963 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 14022 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431 +F V DL+ +Y+FR+RA N G S PS+ +E ++ E P Sbjct: 14023 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071 Score = 63.9 bits (154), Expect = 1e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y + EN+ G Q + V + P PP G D+ +S++LSW + Sbjct: 16793 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16851 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P Sbjct: 16852 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16909 Score = 63.5 bits (153), Expect = 2e-09 Identities = 95/427 (22%), Positives = 150/427 (35%), Gaps = 53/427 (12%) Query: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS 1147 E ES G AP LQDV V G C + D + WT G ++ ++ + S Sbjct: 3479 ECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQS 3538 Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEM 1201 Q G++ ++I D+GLY C+ ND G+ S ++V+ AP S E EM Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEM 3598 Query: 1202 K----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPE 1245 K + S + L S++ V P K P I+ Sbjct: 3599 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVS 3656 Query: 1246 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHC 1305 + + G+ L V G W + S K + L IL + E Sbjct: 3657 NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3716 Query: 1306 GCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-------- 1357 G YT + N G L + K + T S + S L + Sbjct: 3717 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3776 Query: 1358 ---DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEY 1400 G A+ Y++ + TW K+L T S +F V D + Sbjct: 3777 RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 3836 Query: 1401 KFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINT 1456 + +A N+ G S + E E T + + P + K E +D + P +++ Sbjct: 3837 LYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDS 3896 Query: 1457 EQKVSDF 1463 EQ+++ F Sbjct: 3897 EQEIATF 3903 Score = 63.5 bits (153), Expect = 2e-09 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%) Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271 S+ TV + P K P P + + +V+ E + G +V G + + W Sbjct: 16024 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16082 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +K K K E G + + + G +G V P Sbjct: 16083 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16133 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389 P G P A + +S+TL W +YDGGS + Y +E + W + + T F Sbjct: 16134 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16193 Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432 V L+ DH Y+FRV A N G SEPS+ + T ++ + P+ Sbjct: 16194 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16237 Score = 63.5 bits (153), Expect = 2e-09 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+ Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20641 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G A + +V + D P P + T T+ +P P Sbjct: 20642 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20688 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I++ E +V W SEH++ E Sbjct: 20689 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20718 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 T + E+ + + NK G + + +VV K P PP G P + I + Sbjct: 20719 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20775 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404 S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV Sbjct: 20776 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835 Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439 A+N G S+ SE + P P ++ ++D Sbjct: 20836 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20872 Score = 63.2 bits (152), Expect = 2e-09 Identities = 33/95 (34%), Positives = 48/95 (50%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+ Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 I DV +D A KA+N GE + A L+V+ + Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383 P P P D SS++L W + DGGS ++ Y +E+ + WK + T Sbjct: 9399 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9458 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D Sbjct: 9459 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9513 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383 + KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ + Sbjct: 10805 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10863 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432 C T + V L YKFRV A+N G S+P+ E V ++ E P+ Sbjct: 10864 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10912 Score = 63.2 bits (152), Expect = 2e-09 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%) Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063 K V +S PLS P L+ K + TL L P+ G AK D + S Sbjct: 12483 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12533 Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104 +EE D + + + + G + +K E++G A +Q L Sbjct: 12534 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12593 Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 + + + GKKL ++ V P T W + T+ + + + S + I Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12653 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215 + +D G Y A+N +G +V V DAP PP + Sbjct: 12654 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12698 Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 ++DA P + + I+ E V G+ V VT T + Sbjct: 12699 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12749 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 K I E++ +EN G L K+ AQ V +P Sbjct: 12750 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12794 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388 T D + ++W DGGS + Y IE +W AN T RST Sbjct: 12795 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12845 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 + L+ EY FR+ A+N G+S PS+ +E T P +P + EV D Sbjct: 12846 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12895 Score = 63.2 bits (152), Expect = 2e-09 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%) Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25333 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163 Y C+ N G EL V+G +++ +T+ + +T + E PP+F Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25387 Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220 L G+ RF IT P+P VTW K ++P + + G+ L I Sbjct: 25388 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25447 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + V DD YT + N G+ S A+L++ Sbjct: 25448 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477 Score = 62.8 bits (151), Expect = 3e-09 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%) Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143 D EK+ + P FK+KL + + +C+++ DP + W +GK L+ Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203 + + E CS+ A D G+ C A N G S + V D E + E + Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760 Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263 + L + E A T K P I+ +PE +V GE+ +VTG Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820 Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323 W + I++S+ +V + L I+ + G + EN G + +V Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879 Query: 1324 NLTVVDKPD 1332 L + + D Sbjct: 1880 KLEIQQRED 1888 Score = 62.8 bits (151), Expect = 3e-09 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386 KP PP P DI SS+ LSW YDGG +Q Y +E D + W Sbjct: 16532 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16590 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 T+ V+ LL HEY FR+ AIN G E + V EK E P ++++ Sbjct: 16591 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16641 Score = 62.4 bits (150), Expect = 4e-09 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14538 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277 + + N +GK S ++++ LD+ +R T T V +TN Sbjct: 14539 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14596 Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325 I ++ ++ A K C+ G S A N +P ++ Sbjct: 14597 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14656 Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385 ++P ++ T S+++L P+P+ G ++ E +R + T T Sbjct: 14657 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14711 Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425 GL Q + +A R P E + + P+ + + Q++ Sbjct: 14712 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14771 Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 K +K V G PKP V W +G + +Q + A S L + + DSG Sbjct: 14772 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14830 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522 Y TA N G++ T+QV + P F V D Sbjct: 14831 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14869 Score = 62.4 bits (150), Expect = 4e-09 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569 AP +KD G+ L C + G P+P I W G+ + +R + + L Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628 + ED G YTC+A N +G+V S S+ LL P P P+ + Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24333 Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688 + GS + + V G P P + W H +Q SE+ E L ++ V + Sbjct: 24334 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24389 Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 G Y + N G V A+L V+ +P + P + A L S +IS Sbjct: 24390 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24438 Score = 62.0 bits (149), Expect = 5e-09 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 I +D G +TC VN +G S S L++Q + F +ET A VT Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003 Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309 + E K ++S + + + Q G P A Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035 Score = 62.0 bits (149), Expect = 5e-09 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329 +++ + V + TI + H + ++ +NK G + + + Sbjct: 9951 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010 Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383 P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A Sbjct: 10011 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10069 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 S+ V L+ +Y+FRV AIN G S S+ T + P Sbjct: 10070 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10117 Score = 62.0 bits (149), Expect = 5e-09 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y AKN +G A+ S V V D P P +L T+ + T+ Sbjct: 11673 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11716 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 + P D G IT +++RK Q+ + Sbjct: 11717 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11747 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340 + L A E+ + + ENK+G ++ + + +D+P P A Sbjct: 11748 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11805 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 D + + L W YDGGS SY +E + W+ + + + T + V + + Sbjct: 11806 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11864 Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 Y+FRV+ N G S+ + E+ V E ++P ++++S Sbjct: 11865 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11903 Score = 61.6 bits (148), Expect = 7e-09 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143 T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++ Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194 +SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA + Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238 + E + R + + S ATV+ K P+ PPK + PP Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269 Query: 1239 QI 1240 I Sbjct: 270 SI 271 Score = 61.6 bits (148), Expect = 7e-09 Identities = 35/96 (36%), Positives = 46/96 (47%) Query: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 II D ++T A N G ++ + L VE +E Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505 Score = 61.6 bits (148), Expect = 7e-09 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%) Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364 + ++ EN G + + +D DPP G P +I ++TL W Y GG + Sbjct: 15026 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15084 Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421 SY +E D N W + F V L D Y+FRV A N G S PS+ S+ Sbjct: 15085 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15144 Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441 T + E PK +V+V D Sbjct: 15145 ITCRDDVEAPKIKVDVKFKD 15164 Score = 61.6 bits (148), Expect = 7e-09 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PAFK V G+ L + P + W + LK T + + ++I Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15902 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A ED G Y N AG+A + V V D P PP + Sbjct: 15903 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15944 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D T PP K G S+ + V T TW Sbjct: 15945 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15986 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331 S ++ TI A R + GC + + EN+ G S TV P Sbjct: 15987 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 16033 Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387 P GTP + S+ + W DGGS V Y +E + + W +L T Sbjct: 16034 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16093 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F L EY+FRV A N+ G +PS+ SE V P +P E + Sbjct: 16094 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16152 Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475 ++ T + K++ + ++ L G++ Sbjct: 16153 QWKKPTYDGGSKITGYIVEKKELPEGRW 16180 Score = 61.6 bits (148), Expect = 7e-09 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P +K + VH E K+ + P TI W + L T + + S+S+ Sbjct: 16242 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16298 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A+ D G Y AKN AG+ + V V D P PE P V+ Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16341 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275 S T +K PP II + +++ E+ L V Q ++C Sbjct: 16342 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16391 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330 KV G++ T + ++ NK G + + VV K Sbjct: 16392 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16431 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388 PD P P + + S+ + W + DGGS + Y +E D W Sbjct: 16432 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16490 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 V L+ +H+Y+FRV A N G SEPS S Sbjct: 16491 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16521 Score = 61.6 bits (148), Expect = 7e-09 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W+K K + K + G + + + G +G V Sbjct: 18246 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18296 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388 P P G P A I +++TL W +YDGGS + Y +E D + W + T Sbjct: 18297 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18356 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 F V L+ D Y+FRV A N G SEPS S T ++ + P ++ Sbjct: 18357 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18405 Score = 61.6 bits (148), Expect = 7e-09 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%) Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W + Sbjct: 21840 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21895 Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435 + + R T F V L +EY+F V A N G S S L E P P V Sbjct: 21896 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21955 Query: 1436 EVSDDDEKEPEVDY 1449 +V+D + +++ Sbjct: 21956 KVTDTSKTTVSLEW 21969 Score = 61.2 bits (147), Expect = 9e-09 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC Sbjct: 18697 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18753 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 + F V L + EY FR+ AIN G EP+ E+ E P+ E++ Sbjct: 18754 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18805 Score = 61.2 bits (147), Expect = 9e-09 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 +HV G+ + L ++ PP W G L+ ++ + + + ++I + D G Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23502 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223 Y KN G + +V + D P P+ E DAT + Sbjct: 23503 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23547 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P+ A + +++ + + G + ++ +T + KF + + +E+ Sbjct: 23548 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23597 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 + + A + G Y +++++ ++ + + P PP T D+ Sbjct: 23598 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23638 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396 +TL+WY DGGS V Y +E W NK + RST L Sbjct: 23639 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23693 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432 EY+ RV AIN G+ +PS+ S+ + KP+ P+ Sbjct: 23694 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23735 Score = 60.5 bits (145), Expect = 2e-08 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T Sbjct: 13284 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13342 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 F V L+ D +Y+FRV A+N G S+PS Sbjct: 13343 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13371 Score = 60.5 bits (145), Expect = 2e-08 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 + ++P PP D SS L+W +DGGS + Y +E+ + W E Sbjct: 22235 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22293 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 + +F V+ L+ EY+FRV+A N G SEP + + E EP Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22340 Score = 60.5 bits (145), Expect = 2e-08 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P + + K + + C++ G P P++ W+ G + Q ++ D +H L Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24286 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 ++ D G Y+C A+N G++ S L ++ A + P + K + G L Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24343 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589 G PVP +TW + +Q + + T E H+ ++ + H G Y N Sbjct: 24344 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G V V + +K P KPT PI ++ L + + +S Sbjct: 24404 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24440 Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702 PP + W+ N E +E ++ + C E+ G Y A N+ G Sbjct: 24441 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24500 Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748 + +V+ ++ P + +P KP ++TA SC +A P Sbjct: 24501 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24542 Score = 60.5 bits (145), Expect = 2e-08 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G Sbjct: 26542 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26600 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 F L IH D G YTC N +G+ + +LT++ Sbjct: 26601 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26637 Score = 60.1 bits (144), Expect = 2e-08 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384 V KP PP G P D SS++++W YDGGS + Y +EI W+ + A Sbjct: 15448 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15506 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 ++TS+ + L + EYK R+ A+N G EP+ Sbjct: 15507 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15538 Score = 60.1 bits (144), Expect = 2e-08 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W K K + MKV + G Y + EN G + + V Sbjct: 19328 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19376 Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386 DP P G P ++I S++L W YDGG+ + Y +E + + W + + Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19436 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D Sbjct: 19437 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19492 Score = 59.7 bits (143), Expect = 3e-08 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 EK P F K + + ++ G A + G P P++ WF + + S ++ +D D Sbjct: 3643 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3702 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 + SLII +D+ +YTC A N G+ C+A L + + EG + E E Sbjct: 3703 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3751 Score = 58.9 bits (141), Expect = 5e-08 Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 3/114 (2%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1861 +E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350 Query: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME-EGEGEGEEEEE 1914 D L I++ +D+ YT A N++G+ + TA L +E + + G++ E Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRE 3403 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%) Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464 ++ + DS + +P ++ E++ + EVS +L+ TPV + S V Sbjct: 4332 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4391 Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524 ++ L + + +S + S T A ++ + E + E P + L D Sbjct: 4392 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4445 Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580 EG L S+ T + W + + + + + L I EDH G Sbjct: 4446 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4503 Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 Y C A N G+ + SA +TV K AP+ + + L+V G Sbjct: 4504 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4546 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 T ++ P W G EI ES+ SL I D G YTC+A N Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4606 Query: 701 AGEVRTQAVLTVQEP 715 G V A LTV P Sbjct: 4607 YGSVSCTATLTVTVP 4621 Score = 58.9 bits (141), Expect = 5e-08 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%) Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189 W T+K TK + EGSL +++ A+N GQ++ + ++D Sbjct: 7825 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7868 Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249 + +++T + PP D T + PPK I ++ ++K Sbjct: 7869 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7919 Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 R G W+K K + +V + G+++ + G Sbjct: 7920 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7960 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 +G + ++ P P P +D + ++W +GGS + Y Sbjct: 7961 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 8014 Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE Sbjct: 8015 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8074 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456 + +P ++E D E E V +R V + T Sbjct: 8075 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8112 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G+ L+ V P TI W K ++ + + + ++ A+ D G Y Sbjct: 17332 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17391 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 A N AG V V D P P V G S+ K Sbjct: 17392 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17434 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288 +PP I + +++ E+ L V ++ +T Sbjct: 17435 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17470 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343 N K+T L E+ + ++ NK G + + V+ K P PP ++I Sbjct: 17471 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17525 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401 S+T+ W DGGS + Y +E D + W + R T V L DHEY+ Sbjct: 17526 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17585 Query: 1402 FRVRAINVYGTSEPS 1416 FRV A N G EPS Sbjct: 17586 FRVSAENAAGVGEPS 17600 Score = 58.5 bits (140), Expect = 6e-08 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + +F C ++ + V W +G + + ++ D H L + ++ D G Sbjct: 5192 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5248 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ + +G+ + + RL V + F S L+D V EG+ C + + Sbjct: 5249 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5298 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604 + W N + +R+ + + H + + E L +S V E Sbjct: 5299 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5346 Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664 S+ + + L P F L D ++ ++T+ +VS + P V W +G EI Sbjct: 5347 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5397 Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724 S + + G + L I++ +D G Y C+ G +T+A +TV+ + + Sbjct: 5398 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5448 Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781 KP V +G++ ++ P VH W G+ L + E++++ L+L Sbjct: 5449 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5504 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827 Q G+ N + +V + S + + REP + Sbjct: 5505 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5564 Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884 L G + G DR+ ++ G + ++ ED + + +HT Sbjct: 5565 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5617 Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938 E IR + + L +D+ K+ V T LS D+++ + + N QR ++V Sbjct: 5618 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5669 Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997 S ++E K HS + F+ L+ TS+ V + + KL G Sbjct: 5670 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5712 Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055 + + + VE + + + S PV K + +KP NA Sbjct: 5713 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5759 Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112 +K+ K+ LKK +K+D+ GT + + + + L V V E Sbjct: 5760 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5816 Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + ++S D W L G+ L T + +EG + S+ + + G Sbjct: 5817 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5869 Score = 58.5 bits (140), Expect = 6e-08 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%) Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147 R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + + Sbjct: 18394 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18453 Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207 ++ ++ + D G Y N G V V D P P Sbjct: 18454 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18500 Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267 V G ++ P A + II+ E ++ Sbjct: 18501 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18542 Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 +W + ++Q + K+T L E+ + ++ NK G + + V Sbjct: 18543 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18588 Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381 KP P TP S I S+ ++W DGG+ ++ Y +E D W + Sbjct: 18589 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18648 Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 T V L H Y+FRV A N G EPS+ S Sbjct: 18649 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18686 Score = 58.5 bits (140), Expect = 6e-08 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T + Sbjct: 24226 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24284 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 L + +ED G YTC ATN G + + +L ++ + G P+ K G Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24335 Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210 G R GRP P +TW G LQ S +++ Sbjct: 24336 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24373 Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268 L + V + G Y + N G ++ IQ D V E N Sbjct: 24374 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24433 Query: 269 SDV 271 S V Sbjct: 24434 SAV 24436 Score = 58.5 bits (140), Expect = 6e-08 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386 +KP P G P + + S ++W + DGG+ +++Y +E + W + T R Sbjct: 24518 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24576 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE Sbjct: 24577 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24627 Score = 58.5 bits (140), Expect = 6e-08 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156 P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++ Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214 I LPED G Y+ A N AG C + V+ + K+ E R + + L Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25609 Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250 GTES +A V KPA T K +I + E++K+R Sbjct: 25610 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25664 Score = 57.8 bits (138), Expect = 1e-07 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1867 PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +IS DD +YT N GE + +A L+ E Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128 Score = 57.8 bits (138), Expect = 1e-07 Identities = 87/371 (23%), Positives = 148/371 (39%), Gaps = 50/371 (13%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 V KP PP D +S+TL+W YDGGS + Y +EI + + W+ + Sbjct: 17612 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17670 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSELR 17726 Query: 1445 PEVDYR---TVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVW----------A 1491 + R + I+ K +I G+F + +EK A Sbjct: 17727 KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDA 17785 Query: 1492 GKF-FKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI 1550 GK+ K ++ ++ + +++ P+ + + ++ A +V I+ GG + Sbjct: 17786 GKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNY 17845 Query: 1551 IDEDFELTERECIKYMRQISE---GVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFG 1607 + + E T + + S+ VE + + I + + EN V G ++ +D Sbjct: 17846 VIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV---GVPVETVDAV 17902 Query: 1608 LARRLE-----------NAGSLKVLFGTPEF-----VAPEVINYEPIGYATDMWSI---G 1648 A + S +++ PE V V+ +P G T+ WSI Sbjct: 17903 KAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG--TEKWSIVAES 17960 Query: 1649 VICYILVSGLS 1659 +C +V+GLS Sbjct: 17961 KVCNAVVTGLS 17971 Score = 57.8 bits (138), Expect = 1e-07 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%) Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V Sbjct: 17882 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17941 Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 Y +E+ + W +A + + V L EY+FRV+A N G S+P Sbjct: 17942 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17991 Score = 57.8 bits (138), Expect = 1e-07 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Query: 1790 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD Sbjct: 25468 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 Q + + +I ++ +L I D +D Y A N+ G +C A L VE + + Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587 Query: 1907 GEGEEEEE 1914 E + +EE Sbjct: 25588 QEFKSKEE 25595 Score = 57.4 bits (137), Expect = 1e-07 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1867 P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 ++ + +D A YTC+A N G AT +A L VE E Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286 Score = 57.4 bits (137), Expect = 1e-07 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358 QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D Sbjct: 18958 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 19017 Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q Sbjct: 19018 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076 Score = 56.6 bits (135), Expect = 2e-07 Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%) Query: 921 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978 E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V + Sbjct: 4334 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392 Query: 979 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033 S+ ++K + + S + E K E+ L + GP+ P+ + E Sbjct: 4393 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4450 Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083 + NAK DE K + V + VN + H G Sbjct: 4451 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4509 Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138 T + K + + AP K+K++ + VA G C++ S P W G+ + Sbjct: 4510 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4569 Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198 + + + S+ I + D G Y C A N+ G C+ +TV P E Sbjct: 4570 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4628 Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 + R+P+ VL + ++K+P PK PK + PE + E V Sbjct: 4629 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4684 Query: 1256 EL 1257 E+ Sbjct: 4685 EV 4686 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10288 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 +AKN+AG+ + + V V D P T P + S Sbjct: 10289 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10328 Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 ++ F PED G PIT ++ +++ V Sbjct: 10329 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10362 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341 + T+ Q + + EN +G + +A V + P+ P Sbjct: 10363 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10421 Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399 ++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L Sbjct: 10422 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10481 Query: 1400 YKFRVRAINVYGTSEPS 1416 Y++RV A+N+ G +PS Sbjct: 10482 YEYRVSAVNIVGQGKPS 10498 Score = 56.6 bits (135), Expect = 2e-07 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + ++ V P T+ W + LK T+ + + ++I + + D G Y Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A+N G+ + V D P PP + D Sbjct: 14835 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14865 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 + + F D G V Q + TW++ + + + Sbjct: 14866 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14914 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 ++LT Q + + +N+ G + +V P PP GTP + + Sbjct: 14915 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14968 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV Sbjct: 14969 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 15028 Query: 1405 RAINVYGTSEPSQESE 1420 A N+ G S+PS+ SE Sbjct: 15029 IAENMAGKSKPSKPSE 15044 Score = 56.6 bits (135), Expect = 2e-07 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%) Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115 E L ++ E + KND A ++ K + + TA Q + G Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22360 Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175 + +S P + W L LK T + ++ +++++ ++ D G Y +N Sbjct: 22361 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22420 Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235 AG S V V P P + V +++ V PK Sbjct: 22421 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467 Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 + I++ E T W ++ ++ K+ Sbjct: 22468 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22497 Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351 T L E+ + + EN+ G S+ + + + P P P + + ++++++ Sbjct: 22498 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22555 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N Sbjct: 22556 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22615 Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 G S+ S+ S + + P + EV+D Sbjct: 22616 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22644 Score = 56.2 bits (134), Expect = 3e-07 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387 P P P +D S +L+W YDGG + Y +E ++ W + T R T Sbjct: 14367 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14426 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+ Sbjct: 14427 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14477 Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469 RT+ + + F I+ R Sbjct: 14478 -RRTLVVRAGLSIRIFVPIKGR 14498 Score = 55.8 bits (133), Expect = 4e-07 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%) Query: 1777 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1834 P +++E E ++ A ++K KP + V+EG ARF C++ G Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820 Query: 1835 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878 Query: 1895 AELIVETMEE 1904 +L ++ E+ Sbjct: 1879 VKLEIQQRED 1888 Score = 55.8 bits (133), Expect = 4e-07 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 GC + ++ EN+ G + V + P PP DI S+++L+W +DG Sbjct: 14629 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14687 Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 GS + Y IE + W + T + V++L EY F+V A+N G S P +ES Sbjct: 14688 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14746 Query: 1420 ELTTVGEKPEEPK 1432 V E+ P+ Sbjct: 14747 RPVIVKEQTMLPE 14759 Score = 55.5 bits (132), Expect = 5e-07 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 AP F Q LQ V V EG + +S P + W +G+ + T+ + +S Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 ++I + G Y A N +GQA + ++ V A Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP +Q + VR G V L +VTG + + Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 +IQ S ++ + L I A E G Y++ N +G + L V + + P Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200 Query: 1335 A 1335 A Sbjct: 201 A 201 Score = 55.5 bits (132), Expect = 5e-07 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1863 P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G Sbjct: 24619 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24678 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 LII+ V DD Y +A N G + TA L VE Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715 Score = 55.5 bits (132), Expect = 5e-07 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F R + EG F C+I G P PE+ WFK++ I S + I + SL Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26887 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I + D KYT KA N G+ + TA L+V + E Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923 Score = 55.1 bits (131), Expect = 7e-07 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388 P PP P +D SS L W DGGS V Y +E + + W++ R T Sbjct: 10117 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10174 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D Sbjct: 10175 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10227 Score = 55.1 bits (131), Expect = 7e-07 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386 KP P P D + L W DGGS + Y +E W + R Sbjct: 11497 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11556 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 +F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D Sbjct: 11557 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611 Score = 55.1 bits (131), Expect = 7e-07 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268 TES + K K P PP++ + +++ E G +TG + + Sbjct: 12077 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12134 Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328 W+ K MKV+N +H + + EN++G + + V Sbjct: 12135 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12183 Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378 DP P G P D S+TL W YDGG+ + Y +E+ S ++ W Sbjct: 12184 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243 Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 K A F V L + EY+FRV A N G P++ E E E P+ ++ Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303 Query: 1436 EVS 1438 + S Sbjct: 12304 DAS 12306 Score = 55.1 bits (131), Expect = 7e-07 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399 D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L + Sbjct: 23340 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23399 Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424 Y FR+RA N G SEP + TV Sbjct: 23400 YLFRIRAQNEKGVSEPRETVTAVTV 23424 Score = 55.1 bits (131), Expect = 7e-07 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567 AP F L++ V + L C V G P P + W G+ I +Y + G + Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I +D Y A N G VS +A + V P+K P L+ Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24727 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP Sbjct: 24728 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24783 Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734 +D G Y A N G + V V +P G + +S+ + AS Sbjct: 24784 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24843 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760 G S + + + WLR G+A Sbjct: 24844 GGSKITNYIVEKCATTAERWLRVGQA 24869 Score = 54.7 bits (130), Expect = 9e-07 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383 PDPP I +++ LSW DGGS V Y +E WD + + W++ Sbjct: 9707 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9765 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431 F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9812 Score = 54.7 bits (130), Expect = 9e-07 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101 + G + K + G P P + W+++ + + + L C + T L + + DR Sbjct: 20580 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20635 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 G Y + N G+ T+ + + G P+ KT+ E +W Sbjct: 20636 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20687 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204 K+ +V++ + R + + +KGN + +P Sbjct: 20688 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20747 Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260 SV KN G+ + + + VV A +++S ++ D + + Sbjct: 20748 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20807 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320 + K T D R++VT + + + C+ G P +P Sbjct: 20808 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20853 Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378 K D P + + T SSITL ++ + G V GEE + Sbjct: 20854 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20913 Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421 T + PG+ VS A + P+E P+ Sbjct: 20914 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20973 Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478 S K + V+ G P P V W + + GS Y E+ S L + Sbjct: 20974 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 21029 Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528 TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G Sbjct: 21030 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 21088 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 ++ + + TW + + + D + + LAEN Sbjct: 21089 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 21139 Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637 +G E PV ++ API + D DG Sbjct: 21140 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 21185 Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697 V V E W H G I ++ + Q Q L + + G Sbjct: 21186 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21242 Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 + G + + ++ E P VT +G +V + G P P++ WL+D Sbjct: 21243 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21295 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817 G L K++ + E+ TL +K + H G+Y ++L N V C V + + Sbjct: 21296 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21352 Query: 818 ALPRG 822 + P+G Sbjct: 21353 SKPKG 21357 Score = 54.7 bits (130), Expect = 9e-07 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%) Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + + EN G S T+ P P GTP D+ ++TL W DGGS + Sbjct: 21524 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21583 Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419 YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S Sbjct: 21584 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639 Query: 1420 ELTTVGEKPEEP 1431 + ++ P Sbjct: 21640 GIIMTRDENVPP 21651 Score = 54.3 bits (129), Expect = 1e-06 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Query: 1797 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 +EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ + Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557 Query: 1857 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 I + G +L I D A YT A+N G T ++ VE +E E E E + Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613 Score = 54.3 bits (129), Expect = 1e-06 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447 G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W Sbjct: 5247 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5301 Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507 F + ++ + + +H L + + D +L Sbjct: 5302 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5351 Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565 V+E P F+ L D +E + L+C V VP + W +G+ I S G+ Sbjct: 5352 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5409 Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 L I+ A +D G Y C G A VTV + + KP Sbjct: 5410 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5451 Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684 L ++V G +++S P W G + S D + G +H L + Sbjct: 5452 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5506 Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744 TG + +A N+ ++ A L V+E FI+ V C + Sbjct: 5507 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5558 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782 + +P T WL+ + + D FE++++ ++V+K Sbjct: 5559 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5594 Score = 54.3 bits (129), Expect = 1e-06 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158 F+ KL + G+ L + S P + W + L+ + I + +L I Sbjct: 10519 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10574 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 KA D G Y V +N G + CQV V D P PPV Sbjct: 10575 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10616 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 D K P I +K G+ V + + + TC K K + Sbjct: 10617 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10672 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 + +++ ++EN Y + S +A+ V D PD P T Sbjct: 10673 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10717 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395 D S ++W +DGG + +Y +E ++ +K W + T F V DLL Sbjct: 10718 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10772 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448 +Y+FRV A N G +PS S+ + +P V D VD Sbjct: 10773 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10825 Score = 54.3 bits (129), Expect = 1e-06 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QL PV++K L PP F V G+ + GRP Sbjct: 15828 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15870 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242 P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A Sbjct: 15871 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924 Score = 54.3 bits (129), Expect = 1e-06 Identities = 26/77 (33%), Positives = 44/77 (57%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995 Query: 232 TCLVVNGSGKASMSAEL 248 V N G+ + S E+ Sbjct: 16996 GITVANVVGQKTASIEI 17012 Score = 54.3 bits (129), Expect = 1e-06 Identities = 25/72 (34%), Positives = 40/72 (55%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077 Query: 232 TCLVVNGSGKAS 243 T N +G A+ Sbjct: 18078 TVTATNSAGTAT 18089 Score = 54.3 bits (129), Expect = 1e-06 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1865 P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25443 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I+ V DDDA+YT A N GE +C A+L V Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477 Score = 53.9 bits (128), Expect = 1e-06 Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%) Query: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 +S + + A L V P +K + I LEV G A+F C+I+ P+ WFK Sbjct: 4511 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4566 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 + I ES I + + SL I D +YTCKA N G +CTA L V T+ GE Sbjct: 4567 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4624 Score = 53.9 bits (128), Expect = 1e-06 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16706 Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260 T + N SG + SA ++++ LD+ + Sbjct: 16707 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16764 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311 V + +AT VTN K+D L+ A P + P A Sbjct: 16765 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16824 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363 PQPP + ++ + + T S I +Q + R L Sbjct: 16825 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16883 Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411 + + GEE K + PR P + ++D+V + Sbjct: 16884 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16924 Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471 P + S V+ Q +K +SG PKP + W +G P+ +Q I V + Sbjct: 16925 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16981 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499 L + + D G Y T +N GQ + S Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTAS 17009 Score = 53.9 bits (128), Expect = 1e-06 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E A E KP ++D V S A+F K G P P +W KD ++I + +++ Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908 D+ G L I D YTC NS G + + +L ++ +++ E + Sbjct: 26596 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26645 Score = 53.1 bits (126), Expect = 2e-06 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R GRP P++TW + + +V + + L I +++D G Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17786 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289 Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D Sbjct: 17787 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17838 Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328 AK KN +R + AN + + S K+E+ + Sbjct: 17839 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17897 Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375 P + P L +TS+S+ + R G V + P G E K Sbjct: 17898 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17956 Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423 GL S KA N + +P+ + + P + + Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 18016 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 ++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G Sbjct: 18017 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 18075 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 Y+ TA+N+ G + + ++ V V P F V D VI Sbjct: 18076 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 18119 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/82 (29%), Positives = 41/82 (50%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21722 Query: 230 VYTCLVVNGSGKASMSAELSIQ 251 VYT N SG A ++ +Q Sbjct: 21723 VYTVEAKNASGSAKAEIKVKVQ 21744 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + + Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +++ +D+ YTC A N +GE +++L+++ Sbjct: 24288 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24318 Score = 52.8 bits (125), Expect = 3e-06 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 PT + + V G V + + ++G PPP W G++++ESE E Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734 L I+E DTG YT E N G T V+ + +P T P I + S+T S Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23550 Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790 G + L + WL +++ + T F L + + + + G Sbjct: 23551 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23610 Query: 791 QYEILLKNRVGECSCQVSL 809 Y L++ V EC + + Sbjct: 23611 SY---LQSEVIECRSSIRI 23626 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90 AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127 LVI +D G+YT N G + L E + Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131 Score = 52.4 bits (124), Expect = 4e-06 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 1781 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1840 ++A+ + D Q + +A++ + P F V+ G + D G P P V Sbjct: 15816 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15874 Query: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV Sbjct: 15875 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932 Score = 52.4 bits (124), Expect = 4e-06 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%) Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280 K P TP PP+ P + SV L K G +T +++ ++ + Sbjct: 24010 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24069 Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332 H K + + +T L E+ + ++ +N +G S + + VV DKP Sbjct: 24070 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24127 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390 P S I S+TL W DGG + Y +E S + WK+ + F Sbjct: 24128 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24186 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438 + LL EY+FRV A N G S P S +++LT+ GE P K+ +V+ Sbjct: 24187 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24238 Score = 52.4 bits (124), Expect = 4e-06 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++ Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24682 Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 ++ + T D T Y A+N G +S + +L+VE A + + P + + G+ Sbjct: 24683 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24741 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587 ++ G P P ITW GQ + + V P +D G Y A+N Sbjct: 24742 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24800 Query: 588 ALG 590 G Sbjct: 24801 RFG 24803 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G Sbjct: 25273 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25332 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264 Y C VVN G+ S AEL ++G+ + R T Sbjct: 25333 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25367 Score = 52.0 bits (123), Expect = 6e-06 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%) Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164 ++ H+ G L L + P + W + T I ++ GS + I A ED Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10978 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 G+Y +N AG S +V V D P P+ + +S K Sbjct: 10979 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 11026 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P G SV V + W ++ H Sbjct: 11027 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 11064 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341 +E L +AA EN+ G + DP P G P Sbjct: 11065 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11112 Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399 D+ + ++L W DGGS + Y +E + + W + T + V L Sbjct: 11113 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11172 Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 Y+FRV+A N+ G P + EK P E++V Sbjct: 11173 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11209 Score = 52.0 bits (123), Expect = 6e-06 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21721 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145 G YT EA N SG+ + +++ V+ + K +G + G++ + Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765 Score = 51.6 bits (122), Expect = 7e-06 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%) Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469 ++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++ Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158 Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505 + L + +A DSGTYS A+N+ G+ + + L V+ Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 51.6 bits (122), Expect = 7e-06 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327 W K K + + H KV G + + EN G + Sbjct: 20411 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20459 Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +D +PP +DI +S++LSW ++DGGS + Y +E D + W + Sbjct: 20460 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20518 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417 T F + L + +Y+FRV A N G+ S PS+ Sbjct: 20519 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20551 Score = 51.2 bits (121), Expect = 9e-06 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385 + P PP P +D S+++ L W +++GG + Y ++ W + Sbjct: 8695 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8752 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + V+++ +YK RV A+N G P E++ TV E E P E++VS Sbjct: 8753 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8804 Score = 50.8 bits (120), Expect = 1e-05 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%) Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183 PP T+ W + K L + + S ++I + D G Y +N G+ + S Sbjct: 20994 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 21053 Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238 V V D PA+ + SR + L PP++ S + ++K+ A K Sbjct: 21054 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21105 Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298 TW + + ++ SE Sbjct: 21106 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21131 Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356 + +L EN++G + V + PA S D +S+ LSW Sbjct: 21132 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21182 Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 +DGGS + Y +E +TW ++ V L +FRV A N G S+P Sbjct: 21183 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21242 Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439 + TV E P EV++SD Sbjct: 21243 TIGPI-TVKELIITP--EVDLSD 21262 Score = 50.8 bits (120), Expect = 1e-05 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%) Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343 SE K+T L E+ + ++ EN G A L +P P G P +D Sbjct: 21903 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21960 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401 ++++L W +DGG + Y IE+ + W ++ C T + V DL EYK Sbjct: 21961 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 22020 Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 FRV AIN G + + + ++ P+ +++ + Sbjct: 22021 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 22057 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777 G P + + VT LG++ +SC I G P P + W R GK L + + +++ + Sbjct: 24225 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24283 Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 TL + + G Y + N VGE L+LQ Sbjct: 24284 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318 Score = 49.7 bits (117), Expect = 3e-05 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%) Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 S P E + E P F L + VK G +TG+P+P++TW K ++ L+ Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7427 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252 R+++ + I + D G Y VN G+A+ E+++ Sbjct: 7428 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7487 Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 D N S + D ++TN + + DS Sbjct: 7488 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7522 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P PP G P S+ +SW +GGS + Y +E + + W ++ Sbjct: 9294 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9352 Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439 + FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D Sbjct: 9353 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9410 Score = 49.7 bits (117), Expect = 3e-05 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L V PP I W+ L+ + + + E D G Y Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13462 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G+ E + V V D P PPV T + + P Sbjct: 13463 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13504 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P II + ++ + K T C+ FR V N E Sbjct: 13505 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13547 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348 G + + EN+ G V P G +RS SS Sbjct: 13548 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13595 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408 ++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N Sbjct: 13596 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13654 Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 G P SE+T V +D+V D D K Sbjct: 13655 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13680 Score = 49.7 bits (117), Expect = 3e-05 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+ Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16991 Query: 789 AGQYEILLKNRVGECSCQVSLM 810 GQY I + N VG+ + + ++ Sbjct: 16992 GGQYGITVANVVGQKTASIEIV 17013 Score = 49.7 bits (117), Expect = 3e-05 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G Sbjct: 18812 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18869 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277 Y + N SG S +A ++++ LDS + +RE K + D ++TN Sbjct: 18870 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18927 Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330 I ++ + A + NC+ Q G S + + + E+ + Sbjct: 18928 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18987 Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383 + P P + T +T A ++ E + G V + K + T Sbjct: 18988 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 19047 Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431 GL G + V AA R P E KP + VK + + Sbjct: 19048 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 19107 Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491 K G P+ V W +G + ++ + V L + +A D GTY SN Sbjct: 19108 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19166 Query: 492 AQGQLSCSWTLQV 504 + G ++ T+ V Sbjct: 19167 SAGSITVPITIIV 19179 Score = 49.3 bits (116), Expect = 4e-05 Identities = 24/81 (29%), Positives = 40/81 (49%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 13059 Query: 230 VYTCLVVNGSGKASMSAELSI 250 YT N SG S + +L + Sbjct: 13060 DYTITAENSSGSKSATIKLKV 13080 Score = 48.9 bits (115), Expect = 5e-05 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%) Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190 W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167 Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250 P PP S+ + +K TPP I + +++ Sbjct: 14168 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14207 Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310 E+ L W + IQ H+ + + G++ + H G Sbjct: 14208 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14248 Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 G + +VD+ P P P S++ ++ T+SW DGGS + Y + Sbjct: 14249 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14303 Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426 E + + W + V L Y+FRV A N G PS+ S+ + + Sbjct: 14304 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14363 Query: 1427 K--PEEPKDEVEVSDDDEK 1443 P P V+D +K Sbjct: 14364 AAYPPGPPSNPHVTDTTKK 14382 Score = 48.5 bits (114), Expect = 6e-05 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%) Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62 I++T++++ P S P+T A +PPR L +K G + V G P P Sbjct: 12962 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 13020 Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++ Sbjct: 13021 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13077 Query: 121 LTV 123 L V Sbjct: 13078 LKV 13080 Score = 48.5 bits (114), Expect = 6e-05 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%) Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 + +D PP P +D +S++L+W +GGS V Y IE+ W + Sbjct: 23719 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23776 Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 C +T +++ H EY+FRV A N G EP++ V E E P E++ Sbjct: 23777 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23834 Score = 48.1 bits (113), Expect = 8e-05 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566 + + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062 Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 LHI++ +D G YT A N+ G + + V V EK Sbjct: 18063 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18099 Score = 48.1 bits (113), Expect = 8e-05 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QLG PV+++ +E +PS+ E P F T VK + + GRP Sbjct: 19075 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19117 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ + Sbjct: 19118 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19175 Query: 249 SIQGLD 254 +I LD Sbjct: 19176 TIIVLD 19181 Score = 48.1 bits (113), Expect = 8e-05 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%) Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163 C TN ELT + + + V ++ D S P+ T P I + PP+ Sbjct: 19429 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19484 Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 + +VVK G++ + + I GRP P ++W K + ++ AR + + +L + Sbjct: 19485 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19544 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + D G Y + N +G S++ + Sbjct: 19545 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574 Score = 48.1 bits (113), Expect = 8e-05 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%) Query: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810 AV + + S M S + KS L++ + + ++ A LE + E+ Sbjct: 26190 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26249 Query: 1811 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 T+ R + V EG +ARF C +G P P V W + Q + S Q+ + Sbjct: 26250 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26308 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + IS V D+ Y+ NS G+ L ++ Sbjct: 26309 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346 Score = 47.8 bits (112), Expect = 1e-04 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1859 +++ KP+F K + L + A F+C++ DP +V W D + + + ++ Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708 Query: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +E G CSL D TC+A N G +A LIV+ Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749 Score = 47.8 bits (112), Expect = 1e-04 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%) Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322 G P+T ++ ++++ KV + + T+ Q + + NK G + Sbjct: 7210 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268 Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376 VN+ T PDPP D ++S+ L+W DGGS ++ Y +E + Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7327 Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 W T V L Y +RV+A+N G S+PS+ +E + E P+ + Sbjct: 7328 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7387 Query: 1436 EV 1437 +V Sbjct: 7388 DV 7389 Score = 47.8 bits (112), Expect = 1e-04 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%) Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478 K ++ + G P P+ +W +G + ++G ++ EDA S + + + + Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577 Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531 +G YS TA N GQ + + ++V + L V ++ + +G D Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9636 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 ++G + + T ++G+ C G + D L E + AEN G Sbjct: 9637 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9687 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 V ++ ++R P+ P P +K+ G TV +S PP Sbjct: 9688 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9730 Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 + W G + + + ++ + ++++ + +A Sbjct: 9731 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9789 Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756 N+AG + A + + P I + G +V I I G PFPT+ W + Sbjct: 9790 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9849 Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 D K H L +D TLV+ + + G Y I N +G S ++ L Sbjct: 9850 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9906 Score = 47.8 bits (112), Expect = 1e-04 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%) Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630 P D + +A NA+G +S S+ S ++ V P P + GL Sbjct: 21615 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21664 Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690 + G + + V G P P V W +G EI++ + SL +++ + Sbjct: 21665 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21721 Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714 G YT EA N++G + + + VQ+ Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQD 21745 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +++P PP +SD SS+ L W DGGS + Y IE + W + Sbjct: 6984 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 7042 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 ++ V L ++Y +RV A N G S+PS+ T + EP ++ D Sbjct: 7043 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7097 Score = 47.4 bits (111), Expect = 1e-04 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632 +P++ T T L E A Q A V+ S S+ + +A + P + + S L Sbjct: 12941 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 13000 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689 V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D Sbjct: 13001 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 13057 Query: 690 TGTYTCEAWNSAG 702 +G YT A NS+G Sbjct: 13058 SGDYTITAENSSG 13070 Score = 47.4 bits (111), Expect = 1e-04 Identities = 25/82 (30%), Positives = 36/82 (43%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 + KE R I G+P P V+W KG PL RVSV L ++ + D G Sbjct: 13688 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13747 Query: 231 YTCLVVNGSGKASMSAELSIQG 252 YT + N +G + + + G Sbjct: 13748 YTITLKNVAGTKEGTISIKVVG 13769 Score = 47.4 bits (111), Expect = 1e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 L I +++D GKYT ATN +G + + V Sbjct: 18063 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 NA S S + E P + + + L + G + R ++G P P V Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21686 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+ Sbjct: 21687 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744 Score = 47.4 bits (111), Expect = 1e-04 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102 I+ G+ + V G PEP++ W + + + + L G R T VI D G Sbjct: 22754 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22811 Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158 KYT N SG + V+V + V S G+ VS+ ++ +S P + I Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22870 Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213 + T V+ EG+ S +T + +V + P P + +N Sbjct: 22871 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22930 Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269 + G+ ++ G ++ ++ E+S +D + +R T+ Sbjct: 22931 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22990 Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327 D R +VT+++ + C R + A NS+P S SC++ Sbjct: 22991 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 23033 Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376 P +AP+ V+ T SI+L + + +G + E+ A Sbjct: 23034 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23091 Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420 R F +G + AA + ++G + + E +P Sbjct: 23092 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 23148 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479 ++ ++ +++ VSG P P + W +G + S + + S+ L ++ K Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23204 Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G Sbjct: 23205 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23260 Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590 G PV I + T + I + + L EN G Sbjct: 23261 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23314 Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 S V V E +P+ P+K L+V+D ++ T+T ++ Sbjct: 23315 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23350 Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705 P L++G + GT+ + + + P E T T E +R Sbjct: 23351 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23405 Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752 Q V EP + + R ++ G+ V + IAG P P Sbjct: 23406 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23465 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 W G L +++ V + V L +++ G+Y + LKN G S + +++ Sbjct: 23466 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23524 Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 + A ++ EP + GG G ++ + RPGW Sbjct: 23525 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23574 Score = 47.4 bits (111), Expect = 1e-04 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387 P PP G P + + W DGG+ + +Y ++ + + W + T Sbjct: 22935 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22993 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 V L+ +Y+FRV A+N G SEPS+ S + E P Sbjct: 22994 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 23037 Score = 47.4 bits (111), Expect = 1e-04 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63 V + S S++ ++P +P E + + + I+ GA+ + V G P P Sbjct: 23115 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23172 Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 +TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V Sbjct: 23173 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23229 Score = 47.0 bits (110), Expect = 2e-04 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%) Query: 988 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045 ++++ + +GS E + VES +S + S V K + +A ++ Sbjct: 4333 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392 Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105 K + KP E + +S E ++V V + G + P L Sbjct: 4393 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4442 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164 D EG + L +++ + W K + + + Q+ + ++ I+K ED Sbjct: 4443 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4500 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 +G Y C A ND+G+ S ++TV K Sbjct: 4501 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4525 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 + AP K E +V G + ++ + W K ++I ES+ Sbjct: 4526 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4575 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 + +S+ S L IL + CG YT N+ GS LTV Sbjct: 4576 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618 Score = 47.0 bits (110), Expect = 2e-04 Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%) Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810 V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L Sbjct: 4464 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4522 Query: 811 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870 + +A + R EP ++ G + ++R W G+ + E D +R Sbjct: 4523 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4578 Query: 871 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917 +L+ +V + ++T +A + L G+K K L E K Sbjct: 4579 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4636 Query: 918 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963 P E++ ++ L++ + +PK ++ KV P ++V+ +V ++ Sbjct: 4637 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4694 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023 K P P KVP KPA P LPA E A+ P +P+ Sbjct: 4695 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4740 Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083 PV P K A E KP G P + + + ++ + + G Sbjct: 4741 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4795 Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137 + + + F ++++D+ + E G + +C VS P+T I W +G Sbjct: 4796 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4852 Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 ++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P Sbjct: 4853 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4906 Score = 47.0 bits (110), Expect = 2e-04 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%) Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169 EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+ Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25335 Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228 C ND G+ ++ V + + RR T+KK K Sbjct: 25336 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25375 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285 T PP+ ++ GE+V +T TW K ++I+ ++ K Sbjct: 25376 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25435 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334 E+ + +LTI + + YT++ NK G + LTV P P Sbjct: 25436 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25495 Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 G +IR S + TL W DG +IEI + Sbjct: 25496 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25546 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 + +++D LP+ +RV A N G++ ++ + K +E K + E +K+ Sbjct: 25547 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25603 Query: 1445 PEVDYRTVTI 1454 + R I Sbjct: 25604 IDKTLRMAEI 25613 Score = 46.2 bits (108), Expect = 3e-04 Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+ + + +G A FE V G P P VTW + + + + + + G+ + + Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144 ++ ED G Y C+A N G EL V P +K+ + Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3886 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PAVE S + AT + ++K + + +++ + L +PL Sbjct: 3887 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3941 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260 S+ E++ + + + C +NGS S L +Q + S ++F Sbjct: 3942 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3990 Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + ET+A SD K + +S E +++SL + P+ G P Sbjct: 3991 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 4044 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353 S +PP S L S + +P+ + T+ +TLQ Q Sbjct: 4045 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4087 Score = 46.2 bits (108), Expect = 3e-04 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444 GLG D IP+E Q P E + E VK TV+F + G+P P Sbjct: 11184 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11236 Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504 W +G+ ++ E V D S L + RD+G Y T SNA G + + L V Sbjct: 11237 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295 Score = 46.2 bits (108), Expect = 3e-04 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 LP KE + + + ++G P P V+W + P+ + R ++ T +L+++ Sbjct: 13682 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13740 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125 + D GKYT N +G ++ T+ + V G Sbjct: 13741 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13769 Score = 46.2 bits (108), Expect = 3e-04 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%) Query: 1768 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1822 S ++ + P+ P E++ E V + A + +K SK I L VVE Sbjct: 26376 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26435 Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C Sbjct: 26436 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26486 Query: 1883 K 1883 + Sbjct: 26487 E 26487 Score = 45.8 bits (107), Expect = 4e-04 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I + Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188 D G YK + G+ E +C ++V+ Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485 Score = 45.8 bits (107), Expect = 4e-04 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864 PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I + Sbjct: 6067 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6122 Query: 1865 CSLIISDVCGDDDAKYTCK 1883 L+I+ DD+A+Y+C+ Sbjct: 6123 RILVINKCLLDDEAEYSCE 6141 Score = 45.8 bits (107), Expect = 4e-04 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565 ++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G Sbjct: 21652 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21708 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 L ++DA + G YT A+NA G V V + Sbjct: 21709 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21745 Score = 45.4 bits (106), Expect = 5e-04 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++ Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + L+I D KYT A G TA+L VE Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097 Score = 45.4 bits (106), Expect = 5e-04 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%) Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169 RQ TV+ EG+ K V + G P ET+P E A +L G Sbjct: 8754 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8808 Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + + G+ R +TGRP P W K L RV + L I + D G Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8867 Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 Y N G +A L ++ + + + + D E+T I Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8927 Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327 K++K+ + +E + + G + ++ + PP E D Sbjct: 8928 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8987 Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381 P T+P+ ++T S+ITL EPR+ G + E++R P Sbjct: 8988 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 9043 Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423 PT + + D KA N +P+ Q D P + + + Sbjct: 9044 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 9103 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478 +VK + V +V+G+P P++ W T + + ++++ ++ S L + KA Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163 Query: 479 TRDSGTYSCTASNAQGQL 496 D GTY+ TASN G + Sbjct: 9164 REDKGTYTVTASNRLGSV 9181 Score = 45.4 bits (106), Expect = 5e-04 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%) Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567 +V P+FSS +V GQD ++ + G P P ITW +G P++ T + Sbjct: 16926 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16981 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I++ +D G Y N +GQ + S + +K P P P+ Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 17028 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651 +S ++ +S NPP Sbjct: 17029 DVS----------AESITLSWNPP 17042 Score = 45.4 bits (106), Expect = 5e-04 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 + G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077 Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715 T A NSAG +V+ +++P Sbjct: 18078 TVTATNSAGTATENLSVIVLEKP 18100 Score = 45.1 bits (105), Expect = 7e-04 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +K G + E V G P P + W ++G+ + + + T +LV D G Sbjct: 15168 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15226 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160 YT ATN G FAK + V G + V + + P Sbjct: 15227 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15273 Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215 P K+ +V++ + R + + QVT LK L+ + RV K G+ Sbjct: 15274 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15332 Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256 VL ++ D + C S S ++ D A Sbjct: 15333 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15392 Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315 + +++ K T +D+R +V+ + E + + A + SP +P Sbjct: 15393 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15452 Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366 PP + L++ + S A P+ S PE P A GL S Sbjct: 15453 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15511 Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423 + + + GLG +V KA +R +P E + D+ K + Sbjct: 15512 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15566 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481 ++ T++ + G P PEV W + E + ++ S Y L+ D Sbjct: 15567 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15620 Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 SG Y T N+ G S ++V + L V EV + ++ D +++G + Sbjct: 15621 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15680 Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593 V R + + C ++ D L E Y LAEN G + Sbjct: 15681 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15729 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 A K S R P+ P K T +MD ++ +V +S P Sbjct: 15730 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15768 Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 H+G + +G+ + + C E T T + + V Q + Sbjct: 15769 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15824 Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 +P + P I+K + T G+ + + G P P V W +D L Sbjct: 15825 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15883 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802 K T E+ L +K G Y + L N GE Sbjct: 15884 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15923 Score = 45.1 bits (105), Expect = 7e-04 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%) Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284 P PP A P++ + +R E G I W+ K R I + Sbjct: 22532 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22586 Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 KV E K+T L E+ Y L + +A + + D P G P +D+ Sbjct: 22587 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22645 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398 S+++L W +YDGGS V Y IE + + + W + F V L Sbjct: 22646 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22705 Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 Y+FRV A N G S+ S+ + T ++ PK E++ Sbjct: 22706 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22744 Score = 44.7 bits (104), Expect = 9e-04 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%) Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 W+ +G+ I+ES F G L I +V D G YTC E + A L V+E Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905 Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775 + + VT GQ + +SC + + V W +DGK + + G Sbjct: 4906 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4960 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810 + L + AG Y + ++N ECS V ++ Sbjct: 4961 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4996 Score = 44.7 bits (104), Expect = 9e-04 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386 P P G P D+ S+++L W +DGGS + Y +E W T Sbjct: 12884 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12943 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + L +Y+FR A S PS+ S+ T+ + P+ ++ V+ Sbjct: 12944 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12995 Score = 44.3 bits (103), Expect = 0.001 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99 L +K G T +F +RG P P W +G I + + ++ FS L I Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11271 Query: 100 DRGKYTCEATNGSGARQVTVELTV 123 D G+Y +N +G++ V V LTV Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTV 11295 Score = 44.3 bits (103), Expect = 0.001 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%) Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 +EK S + +PV A P F + V+ G + + V G P P V W + Sbjct: 15820 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15879 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718 ++++ + E L I++ ED G Y + NSAGE + T V+ + +P Sbjct: 15880 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15939 Query: 719 TQP 721 T P Sbjct: 15940 TGP 15942 Score = 43.9 bits (102), Expect = 0.002 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V+V+ G R + GRP P+VTW K + + V + M L I +DD G Sbjct: 12311 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12369 Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279 Y+ +VN +G+ ++ + + + S V +T +D +VT+ I Sbjct: 12370 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12429 Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311 ++ + D A P P A++ Sbjct: 12430 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12489 Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365 S+P PPR+ ++ + T P L+ K IT QP R V+ Sbjct: 12490 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12549 Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413 G++ K R A + P G V +A + +P Sbjct: 12550 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12594 Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 PK P+ +K + ++ V G P P W +G + V++ S L Sbjct: 12595 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12652 Query: 474 LLKARTRDSGTYSCTASNAQG 494 + +DSG YS TA N+ G Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673 Score = 43.9 bits (102), Expect = 0.002 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L Sbjct: 12594 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12652 Query: 220 IHGVNQDDVGVYTCLVVNGSG 240 I V + D G Y+ N SG Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%) Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 VK V ++ +SK S +V P R D P + F+ ++EG +++G P Sbjct: 9786 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9839 Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 P +TW + N +P+ T + ++D T +LVI D G YT A N Sbjct: 9840 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9895 Query: 111 GSGARQVTVELTVEG 125 G + L V G Sbjct: 9896 NLGTASKEMRLNVLG 9910 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 1810 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 + +KT++++EV E A F+C++ + P +W K+ I S F+I + LII Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 + +D A+YT N AT T I+ T + EE++ Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938 Score = 43.1 bits (100), Expect = 0.003 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1870 +EV EG+ KI+G P P + WFK +++ + YD D C+L+I Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9879 Query: 1871 DVCGDDDAKYTCKAVNSLGEAT 1892 D YT AVN+LG A+ Sbjct: 9880 QSRRSDTGLYTITAVNNLGTAS 9901 Score = 43.1 bits (100), Expect = 0.003 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 Y N SG A SA +++ LD + K TN V KE IS E+ LD+ Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11723 Score = 43.1 bits (100), Expect = 0.003 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V E K + P + + G R + + G P P W K + + S H + Sbjct: 12583 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12642 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + D + LII DV D Y+ A NS G T +++V Sbjct: 12643 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683 Score = 43.1 bits (100), Expect = 0.003 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1838 NA + SE S + A E P + P + TI V G + + D I G P P Sbjct: 16212 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16268 Query: 1839 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 + W K DQ + + +I D SL + D D Y KA N GE + T + Sbjct: 16269 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16327 Query: 1899 V 1899 V Sbjct: 16328 V 16328 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390 P PP S + S+TL W DGGS + Y IE + + W + Sbjct: 19678 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19736 Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421 V+ L EY++RV A N G S PS+ S L Sbjct: 19737 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19769 Score = 42.7 bits (99), Expect = 0.003 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%) Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150 +G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 +++++ ED+G Y V Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 + G ++ +K KP P I+Q DQKV G+ V+L KV+ + + Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401 Query: 1331 PDP 1333 P Sbjct: 2402 ITP 2404 Score = 42.7 bits (99), Expect = 0.003 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Query: 1811 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1864 F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D Sbjct: 4812 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +I DV D +YTC E T TA+L+VE + Sbjct: 4870 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905 Score = 42.7 bits (99), Expect = 0.003 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%) Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167 + + TV G Q + V++K S P+ T P + PKF Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17329 Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227 +VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D Sbjct: 17330 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17387 Query: 228 VGVYTCLVVNGSGKASMSAELSI 250 G Y N +G S + + Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKV 17410 Score = 42.4 bits (98), Expect = 0.004 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%) Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107 +KS K +++ K + + +N + H G + + T+ A F++ ++D+ Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021 Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167 V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080 Query: 1168 YKCVAKNDAGQAE 1180 Y VA + A+ Sbjct: 3081 YTVVAGGNVSTAK 3093 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 +K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10982 Query: 232 TCLVVNGSGKASMSAELSI 250 + V N +G ++S ++ + Sbjct: 10983 SLTVENPAGSKTVSVKVLV 11001 Score = 42.4 bits (98), Expect = 0.004 Identities = 21/72 (29%), Positives = 34/72 (47%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++++ G R + GRP P++TW K NV L+ + + + L VN+ D G Sbjct: 13398 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13457 Query: 230 VYTCLVVNGSGK 241 Y + N GK Sbjct: 13458 KYILTLENSCGK 13469 Score = 42.4 bits (98), Expect = 0.004 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + + V G P P V W +++++ +FE T L I E D+G Y Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834 Query: 697 AWNSAGEVRTQAVLTVQ 713 A N GEV V+T+Q Sbjct: 14835 ARNIVGEVGD--VITIQ 14849 Score = 42.4 bits (98), Expect = 0.004 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576 KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+ Sbjct: 16245 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16304 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633 D G Y A+N G+ S VTV+ K R P P P+ + G++ K Sbjct: 16305 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16351 Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656 + DG + V ++W Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVW 16379 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 +P VKP FS V G + + I G P P + W KD ++++ + D Sbjct: 16924 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16978 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 +L I + DD +Y N +G+ T + E++ Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 17013 Score = 42.4 bits (98), Expect = 0.004 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795 + + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+ Sbjct: 19105 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19163 Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 + N G + +++++ + P + SC+ + Sbjct: 19164 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19199 Score = 42.0 bits (97), Expect = 0.006 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158 F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I Sbjct: 5982 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 6039 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 PED Y C DA + SC + V Sbjct: 6040 DCTPEDIKTYTC----DAKDFKTSCNLNV 6064 Score = 42.0 bits (97), Expect = 0.006 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E F N+ + E T K V P +V W++ + I GR+ + R Sbjct: 6154 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6212 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 LVI H ED G Y C + +V V Sbjct: 6213 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6243 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 E +F +K + + EG+ F C I+ P V W + + L+ + Sbjct: 6244 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6293 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 V +VL + D+G Y +V G A +A L++ Sbjct: 6294 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6331 Score = 42.0 bits (97), Expect = 0.006 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578 G+ + V G P+P+I W N I+ + EL I A+ ED Sbjct: 9108 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9167 Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605 GTYT A N LG V + V V+++ S Sbjct: 9168 GTYTVTASNRLGSVFRNVHVEVYDRPS 9194 Score = 42.0 bits (97), Expect = 0.006 Identities = 26/93 (27%), Positives = 39/93 (41%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P+ + ++ + L V G+ V + G P P W +G+EI+ E + E Sbjct: 11203 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11262 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 L I+ DTG Y N+AG LTV Sbjct: 11263 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295 Score = 42.0 bits (97), Expect = 0.006 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V G P P+V W G ++G +++ + +L + + DSG YS T N G+ Sbjct: 12325 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12382 Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 + ++V L V +V + V +G V V R TW Sbjct: 12383 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12440 Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609 + T E H+ + +P + + A N G V K S Sbjct: 12441 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12488 Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666 + L S+P P + ++ +++T PP L +G + Sbjct: 12489 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12530 Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716 E+ R T++S+ ++++ TG + A N+ G + V E Sbjct: 12531 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12589 Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776 + P I P +T G+ + I + G P PT W + G+ + H V + + Sbjct: 12590 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12648 Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820 L++K V +G Y + +N G + ++ +++ ++ P Sbjct: 12649 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12692 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T G +V + + G P PTV W +DG L K ++ ++ TL L V + Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 13058 Query: 790 GQYEILLKNRVGECSCQVSL 809 G Y I +N G S + L Sbjct: 13059 GDYTITAENSSGSKSATIKL 13078 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 VV+ G R GRP P W K + L S R + + L + N++D G Sbjct: 22063 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22120 Query: 231 YTCLVVNGSGKASMSAELSI 250 YT V N SG S++ + + Sbjct: 22121 YTLTVENNSGSKSITFTVKV 22140 Score = 42.0 bits (97), Expect = 0.006 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639 + LA+NA G +S + T + + EY AP K L G DL + GS Sbjct: 22709 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22759 Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699 + + V G P P++IW E+ E + G + + I+ D+G YT N Sbjct: 22760 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22819 Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721 ++G T+AV + + D P Sbjct: 22820 ASG---TKAVSVMVKVLDSPGP 22838 Score = 42.0 bits (97), Expect = 0.006 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 T D ++ P E + G+ V ++ G + G+P+P++ W KG+ Sbjct: 22731 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22780 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255 L +VS+ I ++ D G YT V N SG ++S + + LDS Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22835 Score = 41.6 bits (96), Expect = 0.008 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98 +N+ + E TA FE V + P + W +NG I +F + ++G L+I Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899 Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134 ED +YT N + +TV E+TV EG K L Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959 Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168 V K+ GD F A + +++ E +F + Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019 Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 + V E + F C+++ P V W+K + LQ + R+ + ++ + L I D Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078 Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 G YT + +G +A+L ++G D RS +E + Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111 Score = 41.6 bits (96), Expect = 0.008 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V + Q + CE++ + +V W +G V + G I L + A D+GT Sbjct: 4919 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4976 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ T NA L CS ++V V + ++D V + C + P Sbjct: 4977 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 5030 Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 I W + +P + L I++A+PED Y E A +T Sbjct: 5031 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 5086 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 + E R+ E L P+ D+ + + + ++S P W Sbjct: 5087 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 5127 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 G ++ S + G + L + +V + G +A N+ T A+LTV+E Sbjct: 5128 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 5179 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 + F + VT + C + + V W + G + K + F+++ + L Sbjct: 5180 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5236 Query: 780 VLKKVQPWHAGQY 792 V+ Q G Y Sbjct: 5237 VINDSQFDDEGVY 5249 Score = 41.6 bits (96), Expect = 0.008 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6217 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1913 + +D Y C+ +S + EL E + + + EGE+ E Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265 Score = 41.6 bits (96), Expect = 0.008 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%) Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64 A+ ISK S S P + + E P + P+ + + G T + E V G P P + Sbjct: 17295 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17352 Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 W R + I R C I+ T L++ D G+Y A+N +G++ V + Sbjct: 17353 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17408 Query: 122 TV 123 V Sbjct: 17409 KV 17410 Score = 41.6 bits (96), Expect = 0.008 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++VK G + GRP P V W K + L+ A V ++ L I N++D G Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19948 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 YT + N AS++ L ++ LD+ T T DV KE Sbjct: 19949 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19987 Score = 41.6 bits (96), Expect = 0.008 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21723 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 Y+ A NA G ++V+ V P Sbjct: 21724 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21753 Score = 41.6 bits (96), Expect = 0.008 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1864 + P D+ + EG C G P PEV W + I +E F I+ + D Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27080 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +LII DV D YT N G + T + + ++ Sbjct: 27081 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118 Score = 41.2 bits (95), Expect = 0.010 Identities = 24/96 (25%), Positives = 43/96 (44%) Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217 +C P + ++V EG+ P P V+W K ++ S R+++ + Sbjct: 8079 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8138 Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253 LE+ + D G+YT + N G A+ S + + GL Sbjct: 8139 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174 Score = 41.2 bits (95), Expect = 0.010 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570 P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L + Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8141 Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600 ++ D G YT EN LG + S V V Sbjct: 8142 PKSVRADAGIYTITLENKLGSATASINVKV 8171 Score = 41.2 bits (95), Expect = 0.010 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454 VSK + P + QR P + K + EV+E V ++ G+P P + WF P Sbjct: 9794 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9850 Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506 ++ + V D + L C L ++R D+G Y+ TA N G S L V Sbjct: 9851 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9910 Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557 V P F SV D + +G + + R TW+ ++ +P Sbjct: 9911 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9966 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 C + +L L + +A+N G + + + ++ + +P AP Sbjct: 9967 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 10015 Query: 618 SKPT 621 KPT Sbjct: 10016 DKPT 10019 Score = 41.2 bits (95), Expect = 0.010 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K I L V G+ RF I G P P W D I+ H+ ++ D + L I + Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11268 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D +Y N+ G T L V Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTV 11295 Score = 41.2 bits (95), Expect = 0.010 Identities = 23/80 (28%), Positives = 36/80 (45%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G++ ++ I G P P V W +DGK L + E+ TLV+K Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471 Query: 790 GQYEILLKNRVGECSCQVSL 809 GQY + L N G S +++ Sbjct: 18472 GQYILKLSNVGGTKSIPITV 18491 Score = 41.2 bits (95), Expect = 0.010 Identities = 26/85 (30%), Positives = 34/85 (40%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L+L V P IIWT K L + + L G + I+ D G Sbjct: 22752 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22811 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y KN +G S V V D+P Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDSP 22836 Score = 40.8 bits (94), Expect = 0.013 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 +++ + E + ++ I + DTGTY EA N G R AV+ V Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7473 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D Sbjct: 7390 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7448 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y +AVN G AT E+ V Sbjct: 7449 KRSDTGTYIIEAVNVCGRATAVVEVNV 7475 Score = 40.8 bits (94), Expect = 0.013 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389 P PP + I ++ L W DGGS + +Y +E D K W+ + T + T Sbjct: 7779 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7837 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414 V L Y FRV A N G S+ Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSD 7862 Score = 40.8 bits (94), Expect = 0.013 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P IL P + IK G + E V G P P W + + + + + L+ Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12652 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I V +D G Y+ A N SG +++ V Sbjct: 12653 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683 Score = 40.8 bits (94), Expect = 0.013 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%) Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542 ++ +A N +G +S L V +A + + P+F + V+ G+D + G P Sbjct: 15813 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15871 Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V Sbjct: 15872 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15931 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624 V +K P PT P+ Sbjct: 15932 VLDK-------------PGPPTGPV 15943 Score = 40.8 bits (94), Expect = 0.013 Identities = 20/81 (24%), Positives = 39/81 (48%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G Sbjct: 16248 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16307 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y N +G+ S++ + + Sbjct: 16308 NYILKAKNVAGERSVTVNVKV 16328 Score = 40.8 bits (94), Expect = 0.013 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 ++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+ Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16994 Query: 104 YTCEATNGSGARQVTVEL 121 Y N G + ++E+ Sbjct: 16995 YGITVANVVGQKTASIEI 17012 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 ++P + G + + + G P P + W KD + ++++ ++ + + Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 18063 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + DD KYT A NS G AT +IV Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/74 (31%), Positives = 33/74 (44%) Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 Q+ + V G P V W +G ++E+ + T SL I+E ED GTY Sbjct: 19106 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19165 Query: 699 NSAGEVRTQAVLTV 712 NSAG + + V Sbjct: 19166 NSAGSITVPITIIV 19179 Score = 40.8 bits (94), Expect = 0.013 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757 +V EP + T P + PR + G+ + I+ IAG P P + W +D Sbjct: 19462 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19521 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808 G + ++ E++ ++ L +K GQY + LKN G S V+ Sbjct: 19522 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19571 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 6039 Query: 1871 DVCGDDDAKYTCKA 1884 D +D YTC A Sbjct: 6040 DCTPEDIKTYTCDA 6053 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + ++ G T + RV+G PEP +TW + G+ + R L + L I D Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11671 Query: 102 GKYTCEATNGSGARQ 116 GKY A N SG Q Sbjct: 11672 GKYIISAKNSSGHAQ 11686 Score = 40.4 bits (93), Expect = 0.017 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11673 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y +A N+ G S + V + L V V ++ + + G + V Sbjct: 11674 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11733 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596 +P Q S + V + I+ + L + + AEN +G Sbjct: 11734 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11777 Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650 T+ K +L + P +P P +L + D + + ++ G Sbjct: 11778 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11825 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705 P + H ++ S+D+ +G+ + + + + N GE V+ Sbjct: 11826 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11883 Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763 T+ V+ + D +P K V T G ++ + + G PFP V W +D A Sbjct: 11884 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11940 Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 + ++ D L K + G+Y + N G Sbjct: 11941 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11978 Score = 40.4 bits (93), Expect = 0.017 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VK V V G P P V+W +GT ++ EG I++ L L +DSG Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 13060 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y+ TA N+ G S + L+V Sbjct: 13061 YTITAENSSGSKSATIKLKV 13080 Score = 40.4 bits (93), Expect = 0.017 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%) Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL Sbjct: 17303 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17356 Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605 + I+ + + CE A L ++DA+ D G Y A N G S V V ++ Sbjct: 17357 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17413 Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633 P P P+ + G++ K Sbjct: 17414 -----------PGPPEGPVQVTGVTSEK 17430 Score = 40.0 bits (92), Expect = 0.022 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%) Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72 DP+ V L E P IL R IK G T + ++G P P+VTW + + Sbjct: 10894 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10953 Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + R +D G+ + +A H ED G Y+ N +G++ V+V++ V Sbjct: 10954 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 11001 Score = 40.0 bits (92), Expect = 0.022 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482 VK T++ V G P PEVAW + T + R +++ A S L KA+ D Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11966 Query: 483 GTYSCTASNAQGQLSCSWTLQV 504 G Y TA+N G T+ V Sbjct: 11967 GKYVVTATNTAGSFVAYATVNV 11988 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%) Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656 V V+EK S +P VA P S V G + + V +SG P P + W Sbjct: 16899 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16958 Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715 +G ++++ + +L I+E +D G Y N G+ + ++T+ +P Sbjct: 16959 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 17018 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575 KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D + Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y N G S V V ++ P P P+ + G++ Sbjct: 18469 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18510 Score = 40.0 bits (92), Expect = 0.022 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%) Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 Q+ V+ +++ G P P W P +++ L + Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 22116 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y+ T N G S ++T++V + +V ++++ D +++G + Sbjct: 22117 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 22176 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 V R +W Q C + +++ LAE Sbjct: 22177 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22216 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 SA V+E E P+ ++ AP L V+D S+ + + Sbjct: 22217 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22260 Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700 WL H+G Q+ DF E T Q + ++ + + + +A N Sbjct: 22261 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22318 Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 AG + + ++EP + T + +T G I I+G P P V W Sbjct: 22319 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22378 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 + L K+T + +D TL +K +G+Y + L+N G + V++++ Sbjct: 22379 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22437 Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844 P S E + G DGGG++ Sbjct: 22438 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103 G AKF ++ P + W + G+ I + C IR + SL I D G+ Sbjct: 4543 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4598 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 YTC+A+N G+ T LTV G+ V K L +R P E Sbjct: 4599 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4641 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Query: 1788 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V Sbjct: 5686 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5744 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 WFKD + I+ S++ I D LI+ D +YTC Sbjct: 5745 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5784 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73 PSR + ++ EAP L + L +K G + V G PEP++TW + + Sbjct: 7367 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7426 Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 R ++ + ++ I D G Y EA N G VE+ V Sbjct: 7427 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475 Score = 39.7 bits (91), Expect = 0.029 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + + +P P V+W +G V+ + + + D S +L + K+ D+G Sbjct: 8093 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 8151 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y+ T N G + S ++V + + ++ S + + +G +L + Sbjct: 8152 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8211 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597 R T++ P+ + V +D +P + A N +G Sbjct: 8212 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8255 Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657 E PV P P D++V + + MT+ + PP L Sbjct: 8256 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8299 Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712 ++G +G + C + + P TYT + E VR + + Sbjct: 8300 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8357 Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 EP T P P S+ G + + +I+G P+PT+ W++D Sbjct: 8358 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8411 Score = 39.7 bits (91), Expect = 0.029 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L I+ G GR G P+P+V+W ++ + R + T +L D Sbjct: 10523 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10581 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 GKY N +G+R+ ++ V + G PV + F + W Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10633 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221 +K+ ++++ ++G+ V + + + +VS + + IH Sbjct: 10634 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682 Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273 N G+ LV + SM A+ + D+ ++ V E ++ D K Sbjct: 10683 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10735 Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317 +TN I ++ + S A +K+ C R + P PP Sbjct: 10736 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10795 Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373 + +K K SP P+ S +T Q R + G V G+E R Sbjct: 10796 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10855 Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420 A P + P T+ G +D K + G+ D A K +P Sbjct: 10856 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10915 Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 + Q +K T++ + G+P P+V W E + I+V GS L + Sbjct: 10916 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10972 Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499 A D G YS T N G + S Sbjct: 10973 NAAHEDGGIYSLTVENPAGSKTVS 10996 Score = 39.7 bits (91), Expect = 0.029 Identities = 23/81 (28%), Positives = 34/81 (41%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VVK G RF I G P P W ++ +V N VL I + D G Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11274 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y V N +G +++ L++ Sbjct: 11275 EYQITVSNAAGSKTVAVHLTV 11295 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 +++ A + + + P V EAP L + + ++ G +A+ +G P Sbjct: 17688 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17747 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P++TW R T + ++ G+ T L I D GKY + N SG++ V Sbjct: 17748 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17804 Query: 121 LTV 123 + V Sbjct: 17805 VKV 17807 Score = 39.7 bits (91), Expect = 0.029 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L L VS PP I W+ G L + I ++ SL + ++K D G Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23208 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y A+N +G+ + V V D P Sbjct: 23209 KYTIEAENQSGKKSATVLVKVYDTP 23233 Score = 39.3 bits (90), Expect = 0.037 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779 P F +SV G + I+G P P V W RDG+ + T ++ ++ L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839 + V ++G+Y + N G+ + L+++ +A P + L + Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116 Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893 G R G P + DG +++ L ++ E Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174 Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953 ++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231 Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005 RS+ + G + +P K PP P P RS + K +L + S Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287 Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032 S P+ + + P PV + PA Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V + P KP D+ V+EG P P V W KD + ++ S + Sbjct: 8071 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8130 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 D + L + D YT N LG AT + + V Sbjct: 8131 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%) Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575 SV ++ G+ + V G PVP W + R + +EL I+DAL Sbjct: 8804 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8863 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 +DHG Y A N+ G +A V V + +L + P + L SD + Sbjct: 8864 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8918 Query: 636 DGSQVT 641 GS++T Sbjct: 8919 GGSEIT 8924 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785 G + I I G P P W DGKA KD H E +N V +++ + + Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9577 Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810 H G+Y I KN+ G+ +C+V +M Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVM 9604 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725 D HFE G H + + G ++ E S G + + V P P + Sbjct: 16190 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16246 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785 ++ G+S + I G P PT+ W++ + L +T E+ + +L +K Sbjct: 16247 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16302 Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809 +G Y + KN GE S V++ Sbjct: 16303 RVDSGNYILKAKNVAGERSVTVNV 16326 Score = 38.9 bits (89), Expect = 0.049 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%) Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860 A+E P ++D+ V G A+F C ++ +V W + I ES ++ Sbjct: 3481 AKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--RLKQS 3538 Query: 1861 EDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 ++GN L I +V D Y+C N GE T +A L VE E Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPE 3583 Score = 38.9 bits (89), Expect = 0.049 Identities = 21/81 (25%), Positives = 35/81 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + V G + + +V G P P++ W G + + Q + L I+E D G Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672 Query: 692 TYTCEAWNSAGEVRTQAVLTV 712 Y A NS+G + A++ V Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV 11693 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 SV A G+ V + G P PTV W +D K L D + + + L + +V Sbjct: 20975 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 21033 Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 G+Y + ++N VGE SS ++ PA+C+ L Sbjct: 21034 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21067 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT + Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21332 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 +NA+ +++ V L P PSKP PI Sbjct: 21333 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21359 Score = 38.5 bits (88), Expect = 0.064 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%) Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 G E+ T + PAP P PP ++ ++ V GESV L ++G T TW + Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 QI+ S ++ ++L I A E G +T N+ G+ L V Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986 Score = 38.5 bits (88), Expect = 0.064 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 PV ++P P + + +++M G + + V+G P P +W E+ + + Sbjct: 8787 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8845 Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 + GT+ L I++ +D G Y A NS G Sbjct: 8846 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878 Score = 38.5 bits (88), Expect = 0.064 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98 L +K G T + E VRG P P+V W ++ +T R +D + FSL Sbjct: 11906 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11963 Query: 99 EDRGKYTCEATNGSGA 114 D GKY ATN +G+ Sbjct: 11964 SDGGKYVVTATNTAGS 11979 Score = 38.5 bits (88), Expect = 0.064 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%) Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++ Sbjct: 13384 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13436 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515 + +L D+G Y T N+ G+ + ++V + V E++ Sbjct: 13437 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13496 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V + +I+G ++ V+ R +W + T E + + Sbjct: 13497 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13547 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 + AEN G + + +R + V S+ P+ DLKV Sbjct: 13548 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13588 Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691 S+ + ++ G P G+ I DF E+ Q SL +Q + T Sbjct: 13589 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13642 Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744 T+ A N GE T + +TV D P K A + + I Sbjct: 13643 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13701 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P+V W + L DT V + TL++ Q AG+Y I LKN G Sbjct: 13702 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760 Query: 805 CQVSL 809 +S+ Sbjct: 13761 GTISI 13765 Score = 38.5 bits (88), Expect = 0.064 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 PAF L + G K + G P P VTWH++ P+ R + L Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15901 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I ED G Y + TN +G T+ + V G + + D + Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15956 Query: 153 PSIWGECPPKF 163 WG PPK+ Sbjct: 15957 ---WG--PPKY 15962 Score = 38.5 bits (88), Expect = 0.064 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 RD VV G R + + G P P + W + D+ I ES +I + D LI+ D Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17385 Query: 1875 DDDAKYTCKAVNSLG 1889 D +Y +A N G Sbjct: 17386 IDGGQYILRASNVAG 17400 Score = 38.5 bits (88), Expect = 0.064 Identities = 22/83 (26%), Positives = 37/83 (44%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + K G I+GRP P+VTW + L+ + RVS++ L + + D G Sbjct: 22352 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22411 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y + N +G + S + + G Sbjct: 22412 RYFLTLENTAGVKTFSVTVVVIG 22434 Score = 38.1 bits (87), Expect = 0.083 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%) Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 PV W+ +N +PI+ + E GV +P+ A NA+G Sbjct: 8020 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 8063 Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658 + S SE ++ P KPT + D+ V++G ++++ V P P V W Sbjct: 8064 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117 Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717 +G E++ S+ + L + + D G YT N G V + P Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8175 Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771 P K +T S SC + +P P +H++ + + + T + V+ Sbjct: 8176 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8225 Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 E+ + +K + P + + N+VG Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8255 Score = 37.7 bits (86), Expect = 0.11 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%) Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672 PT + L D +KV G V + V+G P P++ W N I++ D Sbjct: 9090 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9149 Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704 + + L I + ED GTYT A N G V Sbjct: 9150 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9181 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/73 (27%), Positives = 33/73 (45%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V++K G+ R ++GRP P + W K L+ +A++ + + L + D G Sbjct: 15166 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15225 Query: 230 VYTCLVVNGSGKA 242 YT N G A Sbjct: 15226 AYTLTATNPGGFA 15238 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86 +AP L P+ + + G T E +RG P P V W ++G+ + + R + I+ Sbjct: 18398 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18457 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 T +LV+ D G+Y + +N G + + + + V Sbjct: 18458 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18493 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663 PS+ T PI ++ + D+K D G + + ++G P P + W +G EI Sbjct: 19466 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19525 Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 +E L +++ DTG Y N AG Sbjct: 19526 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19564 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/83 (24%), Positives = 38/83 (45%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 + G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21724 Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191 AKN +G A+ +V V D P Sbjct: 21725 TVEAKNASGSAKAEIKVKVQDTP 21747 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1876 ++++ G R + G P P VW K++ + + R + D G S LII D D Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8865 Query: 1877 DAKYTCKAVNSLGEATCTAELIV 1899 +Y A NS G A + V Sbjct: 8866 HGRYVITATNSCGSKFAAARVEV 8888 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+ Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11671 Query: 790 GQYEILLKNRVG 801 G+Y I KN G Sbjct: 11672 GKYIISAKNSSG 11683 Score = 37.4 bits (85), Expect = 0.14 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L +V G P+P ++W +G +P + + + + L + +D G YT Sbjct: 13005 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 13064 Query: 585 AENALGQVSCSAWVTVHEK 603 AEN+ G S + + V +K Sbjct: 13065 AENSSGSKSATIKLKVLDK 13083 Score = 37.4 bits (85), Expect = 0.14 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%) Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78 VDP R+ P + + + G + K + + G P P + W + Q +++ R Sbjct: 16233 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16284 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + T SL + D G Y +A N +G R VTV + V G V+S Sbjct: 16285 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16343 Query: 139 TLGDR 143 ++ Sbjct: 16344 VTAEK 16348 Score = 37.4 bits (85), Expect = 0.14 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480 V+ + + G P PE+ W R+EG +V + G +Y L + Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17783 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y N+ G S T++V + LAV EV + ++ + +I+G V Sbjct: 17784 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17843 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 + R YA + + +++ + +AEN G Sbjct: 17844 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17891 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 V V + + +E P P K T + D SQ + ++ PE Sbjct: 17892 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17932 Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703 H+G + +GT+ +C V +G + +A+N G+ Sbjct: 17933 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17988 Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762 + + D T QP + + G+ + I + G P P + W++DG+ L Sbjct: 17989 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 18047 Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 K T V + L +K+ G+Y + N G + +S+++ Sbjct: 18048 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096 Score = 37.4 bits (85), Expect = 0.14 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%) Query: 1791 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 D S + +A+E+ +P F S+ + L V G++ G P P V+W K D Sbjct: 19862 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19920 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 +R + D SL I + +D KYT N L A+ T L+V+ ++ Sbjct: 19921 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19971 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97 P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ + Sbjct: 20177 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20235 Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137 D G+Y A N SG + + + V G V+S Sbjct: 20236 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y + Sbjct: 21668 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21726 Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819 KN G ++ + +Q++ + + Sbjct: 21727 EAKNASGSAKAEIKVKVQDTPGKVV 21751 Score = 37.0 bits (84), Expect = 0.19 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%) Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137 + H G + + P + V V EG+ +C+V+ P + W LNG+ Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834 Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195 ++ +K + +G + + I D G K A+N G E ++ + S Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893 Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 +APE RP+ + + + +P T K + + + +KV ES Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949 Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290 EL K + IT +K RK+ + E + K +E Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009 Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340 G K+TI L+ E + + +G A + VV KPDP Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400 WY + IE D W E C ++D+ + Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101 Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451 V+AIN+ G + Q +L T ++ ++ KD + + + EP V + Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161 Query: 1452 VTINTEQKVSDFY 1464 E D Y Sbjct: 2162 YKDGMEVHEGDKY 2174 Score = 37.0 bits (84), Expect = 0.19 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%) Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994 P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + + Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916 Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054 +T K V K + + K E + + + T + A Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967 Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101 LKS K+E +++ + H T+ EK++ E + T P FK Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027 Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152 +++Q V +G + +V P W NG K ++ + E ++ Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178 C + I ED A N AG+ Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + VSG PPP V W N NE ++ E S+ I+ G Y+ Sbjct: 10234 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10291 Query: 697 AWNSAGEVRTQAVLTV 712 A N AGE + ++ V Sbjct: 10292 AKNEAGERKKTIIVDV 10307 Score = 37.0 bits (84), Expect = 0.19 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1870 T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I Sbjct: 11608 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11664 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA 1895 + D KY A NS G A +A Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSA 11689 Score = 37.0 bits (84), Expect = 0.19 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 1800 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1853 V E+ VK K + DL+ V G R + + G P PEV W KD + +R Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941 Query: 1854 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++ D + S ++ D KY A N+ G A + V Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988 Score = 37.0 bits (84), Expect = 0.19 Identities = 22/92 (23%), Positives = 40/92 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G ++ + V G P P W +E+ S + + L I++V +D+G Sbjct: 12603 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12662 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723 Y+ A NS+G + + V + QP F Sbjct: 12663 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12694 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 + + G + R I+G P PEV W K D IR++ + SL++ +V D Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16703 Query: 1878 AKYTCKAVNSLG 1889 KYT NS G Sbjct: 16704 GKYTLTLENSSG 16715 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 1809 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1865 P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20623 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 S++I D + Y K N++G A+ T Sbjct: 20624 SILIKDADRLNSGCYELKLRNAMGSASAT 20652 Score = 37.0 bits (84), Expect = 0.19 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V + G + I+G+P P + W K + LQ +A V V + + I ++ + G Sbjct: 20577 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20636 Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254 Y + N G A SA + +Q LD Sbjct: 20637 CYELKLRNAMGSA--SATIRVQILD 20659 Score = 36.6 bits (83), Expect = 0.24 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%) Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 RF A E R + PK T +VV G+ P+ + W K N PL Sbjct: 6677 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6736 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + +E+ ++LE + D G Y ++ N GKA L + Sbjct: 6737 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6781 Score = 36.6 bits (83), Expect = 0.24 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223 V+EG KI G P P +TW K P +P + V + N + V L I Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9881 Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252 + D G+YT VN G AS L++ G Sbjct: 9882 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9910 Score = 36.6 bits (83), Expect = 0.24 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586 G L ++G P P++TW + AR ++L I++A ED G Y+ E Sbjct: 10928 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10987 Query: 587 NALGQVSCSAWVTVHEK 603 N G + S V V +K Sbjct: 10988 NPAGSKTVSVKVLVLDK 11004 Score = 36.6 bits (83), Expect = 0.24 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%) Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643 A+N G +S + T + K EY P PT L + G + + Sbjct: 14045 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14095 Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703 + + G P P+ W G +I+ S+ T L I+ +D G YT A N G Sbjct: 14096 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14155 Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 +TV + P IS + A+L Sbjct: 14156 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14186 Score = 36.6 bits (83), Expect = 0.24 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20242 Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725 A NS+G + ++ + P T P IS Sbjct: 20243 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275 Score = 36.6 bits (83), Expect = 0.24 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 1794 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1850 +AF + +E P ++P T +++ GS D I G P P+V W ++ ++ Sbjct: 22326 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22384 Query: 1851 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 E+ I +D +L + D D +Y N+ G T + ++V Sbjct: 22385 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432 Score = 36.2 bits (82), Expect = 0.32 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128 NC+ G D N K S P + L+DV V G+ C++S + Sbjct: 5862 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5920 Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174 + W L GK L+ + ++ EG + ++++ ED G + AK+ Sbjct: 5921 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5966 Score = 36.2 bits (82), Expect = 0.32 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%) Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G Sbjct: 10538 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10596 Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 + V V P SF V KD VI Sbjct: 10597 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10626 Score = 36.2 bits (82), Expect = 0.32 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 ++ + G++ + + G P PT+ WLR K + +++ E+ + L++K Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17387 Query: 789 AGQYEILLKNRVGECSCQVSL 809 GQY + N G S V++ Sbjct: 17388 GGQYILRASNVAGSKSFPVNV 17408 Score = 35.8 bits (81), Expect = 0.41 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P T L V +EG + + IT + V W N + + + L I Sbjct: 4435 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4492 Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250 VN +D G Y C +N SGK + SA+L++ Sbjct: 4493 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4523 Score = 35.8 bits (81), Expect = 0.41 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%) Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 T S ++ + E ++ +A N G + ++ L V + D P Sbjct: 9046 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9090 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204 ++ R S+ G+ + VK G+ +TG P P++ W K ++ Sbjct: 9091 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9140 Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260 + VS L I ++D G YT N G + + + S R+ Sbjct: 9141 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9200 Query: 261 VRETKA 266 V + KA Sbjct: 9201 VTDIKA 9206 Score = 35.8 bits (81), Expect = 0.41 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G +V I G P PT W DG + K H+ V + L +K G+Y+I Sbjct: 11220 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278 Query: 795 LLKNRVGECSCQVSL 809 + N G + V L Sbjct: 11279 TVSNAAGSKTVAVHL 11293 Score = 35.8 bits (81), Expect = 0.41 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 EAP +L P L IK G T + G P P+ +W + G+ I + Sbjct: 14069 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14128 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + + +A + D G+YT ATN G + V++TV Sbjct: 14129 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14164 Score = 35.8 bits (81), Expect = 0.41 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584 G + ++ V G P P +TW Q ++ + A L+I + + D G Y Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 A N +G+V + VH+ P PT PI Sbjct: 14835 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14861 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16705 Query: 104 YTCEATNGSGARQVTVELTV 123 YT N SG + V + V Sbjct: 16706 YTLTLENSSGTKSAFVTVRV 16725 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P+ LP +K K + +G P+ V W ++GQ + R + + SL Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19148 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I +ED G Y +N +G+ +TV +T+ Sbjct: 19149 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19177 Score = 35.8 bits (81), Expect = 0.41 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 1833 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 +G P P V W KD++++ + I+ + D + L I V +D KY N +GE Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 21047 Score = 35.8 bits (81), Expect = 0.41 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142 +T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + + Sbjct: 27010 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27069 Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + L ++ I +D GLY N+ G + + + Sbjct: 27070 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115 Score = 35.4 bits (80), Expect = 0.54 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L ++ V+E + L C+VS P A +IW + + T + EG + I+ Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6218 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219 A ED G Y C R P S +D Sbjct: 6219 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6237 Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279 VK + + I P++ ++ GE E ++ + W + K ++ Sbjct: 6238 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6287 Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 + V L + A + G Y ++V G+ +A +LTV++K Sbjct: 6288 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6334 Score = 35.4 bits (80), Expect = 0.54 Identities = 16/82 (19%), Positives = 37/82 (45%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 ++ ++ G+ + + +G+P+P+V+W K + R + LE + D Sbjct: 10522 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10581 Query: 229 GVYTCLVVNGSGKASMSAELSI 250 G Y +V N +G ++++ Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV 10603 Score = 35.4 bits (80), Expect = 0.54 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676 KP + L G+ L V G + + V G P PEV W + ++ S + R Sbjct: 11895 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11952 Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + + D G Y A N+AG A + V Sbjct: 11953 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988 Score = 35.4 bits (80), Expect = 0.54 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 + +A+NA G +S + T + K E LP P + + V G Sbjct: 17288 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17338 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 + V G P P + WL EI+ES + + L +++ D G Y A N Sbjct: 17339 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17398 Query: 701 AG 702 AG Sbjct: 17399 AG 17400 Score = 35.4 bits (80), Expect = 0.54 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + +K G K + G P P ++W ++G I R + T L + D Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19552 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157 G+Y N +G R V V V G ++ ++ S P + I Sbjct: 19553 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19612 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205 K T + EG++ SCK+T LKGN + +P Sbjct: 19613 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19665 Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 V++ + V LEI V ++ + + C S S + I+ + + Sbjct: 19666 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19723 Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314 +VR K D+R + T + E ++ + AA S S R P + P Sbjct: 19724 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19779 Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373 PP + K+ +S K + A P+ + + + + S G E Sbjct: 19780 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19839 Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430 A + R +G+ D S +++ +I E + + F ++ VK + Sbjct: 19840 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19898 Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490 G P P V W T +R + ++ + S L + A DSG Y+ T Sbjct: 19899 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19955 Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526 N S + ++V + V K+ AV+ Sbjct: 19956 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19991 Score = 35.4 bits (80), Expect = 0.54 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V++G + R + I G+P P W K + A ++ SE + L I ++ D G Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23898 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y ++ N GK ++ ++ + G Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIG 23921 Score = 35.4 bits (80), Expect = 0.54 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1867 P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26126 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 I D DD Y N GEA+ A L V Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D++V E A+F+C++ P W K Q I F++ D + S++I Sbjct: 5537 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5594 Query: 1871 DVCGDDDAKYTCKA 1884 +D+AKY +A Sbjct: 5595 SAAFEDEAKYMFEA 5608 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 R+VV G + R ++G+P P VTW L A + + + V I + Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10285 Query: 229 GVYTCLVVNGSGK 241 GVY+ L N +G+ Sbjct: 10286 GVYSLLAKNEAGE 10298 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 ++ G + VRG P P+VTW + G + G L+D LVI +D Sbjct: 12313 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12368 Query: 102 GKYTCEATNGSGARQVTVELTV 123 GKY+ N +G + V V + V Sbjct: 12369 GKYSLTLVNPAGEKAVFVNVRV 12390 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 L V G+ D + G P P V W KD ++ + ++ + C+L + V D Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 YT A NS G + T +L V Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080 Score = 35.0 bits (79), Expect = 0.70 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%) Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 VA AP + L+GL DL + + S + + + G P P V W + + Sbjct: 13667 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13726 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721 E +L + + D G YT N AG + T ++ V +P T P Sbjct: 13727 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13777 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%) Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201 D + AP + P+I K G +V + I G+P P+ +W K + Sbjct: 14066 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14115 Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 +PS ++ +L I + D G YT N G Sbjct: 14116 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 +V G ++ + I+G P P V RDG L K T F + T+ LK+ Sbjct: 20180 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20238 Query: 789 AGQYEILLKNRVGECSCQVSLML 811 AG+YEI N G +++++ Sbjct: 20239 AGRYEITAANSSGTTKAFINIVV 20261 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565 V+++ ++ V+K A G L+ + G P P I W + + +Q C + Sbjct: 20566 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20622 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 A + I+DA + G Y NA+G S + V + +K Sbjct: 20623 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20660 Score = 34.7 bits (78), Expect = 0.92 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V P+ W G PV + + E+ G Y Y A N QG Sbjct: 7319 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7365 Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553 S T +++ + E F V L V G L +V G P P+ITW Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425 Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 + Q R T E + + I D+ D GTY A N G+ + V V +K Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7478 Score = 34.7 bits (78), Expect = 0.92 Identities = 16/67 (23%), Positives = 28/67 (41%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + G P P + W+ E+ + + SL +++ D+G Y + Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16312 Query: 697 AWNSAGE 703 A N AGE Sbjct: 16313 AKNVAGE 16319 Score = 34.7 bits (78), Expect = 0.92 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451 +SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G Sbjct: 17299 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17357 Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 + E+ L + A D G Y ASN G S Sbjct: 17358 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17403 Score = 34.7 bits (78), Expect = 0.92 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ AT + ++G PEP+V W + +T + + +F+ LVI V D G Sbjct: 18814 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18869 Query: 103 KYTCEATNGSGARQVTVELTV 123 +Y N SG++ V + V Sbjct: 18870 RYNLTLENNSGSKTAFVNVRV 18890 Score = 34.7 bits (78), Expect = 0.92 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 +KP V + D +G P V W KD Q+++E+ + + S Sbjct: 19088 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19146 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + +D Y NS G T +IV Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179 Score = 34.3 bits (77), Expect = 1.2 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 ++D V E F+C++ + WF+++++I +S + I +D +L I D Sbjct: 6341 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6398 Query: 1875 DDDAKYTCKAVNSLGE-ATCTAELIVE 1900 DD A Y N GE A LIVE Sbjct: 6399 DDQANYNVSLTNHRGENVKSAANLIVE 6425 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%) Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470 +A PK ++ Q V + + PK E WF E P+ + +I+ + S Sbjct: 6692 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6748 Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523 +L+A+ D G Y N G+ L+ V L V E S+ + Sbjct: 6749 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6807 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549 + +G ++ V + R TW+L Sbjct: 6808 PLTDGGSKIIGYVVERRDIKRKTWVL 6833 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57 G+ L S +K +S DPS + PLT AF+ P +L K+G + Sbjct: 7054 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7111 Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 GYP P TW + + +G R + + LVI D+G YT + N Sbjct: 7112 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7166 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225 G + VK G R + G+P P+V W K L S RV + + + + Sbjct: 11904 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11963 Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250 D G Y N +G A +++ Sbjct: 11964 SDGGKYVVTATNTAGSFVAYATVNV 11988 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%) Query: 1812 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1871 S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D Sbjct: 17723 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17778 Query: 1872 VCGDDDA-KYTCKAVNSLG 1889 C +DA KY K NS G Sbjct: 17779 NCDRNDAGKYILKLENSSG 17797 Score = 34.3 bits (77), Expect = 1.2 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%) Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77 P V + E P + L R + +++G + ++G P P W + GQ I+ Sbjct: 23817 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23874 Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126 R ++ T LVI D G Y N G + V +++ V GS Sbjct: 23875 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23922 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G + I ++G P PTV W + + L ++ + ++V+K Q H Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10285 Query: 790 GQYEILLKNRVGE 802 G Y +L KN GE Sbjct: 10286 GVYSLLAKNEAGE 10298 Score = 33.9 bits (76), Expect = 1.6 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%) Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 +RG PVP W +G I ++ + + L I++ L D G Y NA G + Sbjct: 11229 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11288 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + +TV + P PT PI ++D + MT +S PP + Sbjct: 11289 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11325 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 G A R + + G P P + W KD + + + +I D + +L+ D D YT Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15229 Query: 1883 KAVNSLGEA 1891 A N G A Sbjct: 15230 TATNPGGFA 15238 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%) Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70 +P+ V P E +LPP + + I+ T + ++G P P+V W R+ Sbjct: 15536 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15593 Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 G L I T S L++ V+ D GKY N SG++ V + V Sbjct: 15594 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15643 Score = 33.9 bits (76), Expect = 1.6 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G + + V + G P PEV W EI+++ T SL + V D+G Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16704 Query: 692 TYTCEAWNSAG 702 YT NS+G Sbjct: 16705 KYTLTLENSSG 16715 Score = 33.9 bits (76), Expect = 1.6 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%) Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75 +++ P V + +T E +P + ++ G E +G P+P ++W ++G P+ Sbjct: 21242 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21301 Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 F+ +L I +E GKYT N ++ V +TV Sbjct: 21302 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21346 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%) Query: 1796 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1845 + E++AE ++P I DLE+ + G++ R + G P P + W K Sbjct: 23123 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23177 Query: 1846 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 Q I + ID E + LI+ V D KYT +A N G+ + T Sbjct: 23178 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23224 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D V EG A F C++ + VVWFK+D + SR I E L + Sbjct: 5271 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5328 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +V DD ++ + + E + TA+L V Sbjct: 5329 EVTLDDISQIKAQ----VKELSSTAQLKV 5353 Score = 33.5 bits (75), Expect = 2.0 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+ Sbjct: 5626 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5683 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCT 1894 D+ DD ++ +A+ EA T Sbjct: 5684 DLSIDDTSQIRVEAMGMSSEAKLT 5707 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/72 (27%), Positives = 32/72 (44%) Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244 TG P+P TW G+ L+ RV + + L I + D G+YT + N S Sbjct: 7114 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173 Query: 245 SAELSIQGLDSA 256 ++++ SA Sbjct: 7174 EIDVNVIARPSA 7185 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%) Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69 S IS+ ++ DP P L ++ + EG R P P V+WH++ Sbjct: 8067 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8118 Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125 G+ + + R + V +V D G YT N G+ ++ + V G Sbjct: 8119 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8173 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582 G L+ VRG P P + W + RS A ++ + A D G Y Sbjct: 11911 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11970 Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621 A N G A V V +K ++ ++ V+ + T Sbjct: 11971 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 12009 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96 + L ++ G T + V+G P P++TW + + R LD I+ T F + V Sbjct: 13396 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13451 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 ++ D GKY N G ++ T+ + V Sbjct: 13452 NKYDAGKYILTLENSCGKKEYTIVVKV 13478 Score = 33.5 bits (75), Expect = 2.0 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 VK V S S S DP E P F + + L +K GA+ RG P Sbjct: 19852 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19909 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P V W + + + R +D T SL I + D GKYT N A +T+ Sbjct: 19910 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19966 Query: 121 LTV 123 + V Sbjct: 19967 VKV 19969 Score = 33.5 bits (75), Expect = 2.0 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572 S + K V G F + RG PVP + W +P R+ + L I++ Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19941 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600 A D G YT +N L S + V V Sbjct: 19942 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19969 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19948 Query: 692 TYTCEAWN 699 YT N Sbjct: 19949 KYTLTIQN 19956 Score = 33.1 bits (74), Expect = 2.7 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G KL+ + +LSV+ ++ I R+L E FE + + Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W+ + I ++ ++ + + L + + ++D GKYT A G + +L Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 TV G +SK L D+ V E Q F Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C++ P + WL+ L + + + L I DD+G YT V Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653 Query: 242 ASMSAE 247 A + E Sbjct: 2654 AKLKVE 2659 Score = 33.1 bits (74), Expect = 2.7 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 1776 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1821 S T +++E + ++ + L+ +++ K VK PYF+ + D V Sbjct: 5311 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5370 Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E C++ D V WFKD + I S + I D L I D +Y Sbjct: 5371 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5427 Query: 1882 CKAVNSLGEATCTAE 1896 C +A T E Sbjct: 5428 CDCGTDKTKANVTVE 5442 Score = 33.1 bits (74), Expect = 2.7 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%) Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501 K EV W L V Q ++ + H L + + RD G Y A + + + Sbjct: 6634 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6690 Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561 + AP + +D V G+ + P W +P+ Sbjct: 6691 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6742 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591 A I +A D G Y + +N G+ Sbjct: 6743 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6772 Score = 33.1 bits (74), Expect = 2.7 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160 + V G+ + + V+ P I W+ N + K T + +++E + +SI KA Sbjct: 9103 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9162 Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 + ED+G Y A N G + V V D P+ Sbjct: 9163 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9194 Score = 33.1 bits (74), Expect = 2.7 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 1816 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875 R+ + G R I+G P P+V W K+D+ +ID G+ L I + + Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10977 Query: 1876 DDAKYTCKAVNSLGEATCTAELIV 1899 D Y+ N G T + +++V Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001 Score = 33.1 bits (74), Expect = 2.7 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575 +D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D + Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19549 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y +N G S + V +K P P P+ + GL+ Sbjct: 19550 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19591 Score = 33.1 bits (74), Expect = 2.7 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ GA+ + +G P P W + ++ D +FS L + + D G Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22119 Query: 103 KYTCEATNGSGARQVTVELTV 123 KYT N SG++ +T + V Sbjct: 22120 KYTLTVENNSGSKSITFTVKV 22140 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 + D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+ Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373 Query: 1875 DDDAKYTCKAVNSLGEAT 1892 +D Y+ + +LG +T Sbjct: 2374 EDAGNYSF-TIPALGLST 2390 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163 G ++ + + P W +GK K K + L + + I + Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 G Y AKN AGQ +C+V V D P Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKVMDVP 9607 Score = 32.7 bits (73), Expect = 3.5 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1881 GS D + G P+P+++W K D+ + + Y G + + C D KYT Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22814 Query: 1882 CKAVNSLG 1889 N+ G Sbjct: 22815 LTVKNASG 22822 Score = 32.3 bits (72), Expect = 4.6 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 1816 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1873 ++LE++EG A F C I E +P V W +DD+++ + + D L++ D Sbjct: 6254 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6309 Query: 1874 GDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y V +G A A L V Sbjct: 6310 LQDMGTY----VVMVGAARAAAHLTV 6331 Score = 32.3 bits (72), Expect = 4.6 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%) Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 P+ AP + L L + G +T + SG P P+V W + ++ E + H Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562 Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702 + T +L ++++ + D+G Y NS G Sbjct: 10563 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10593 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575 KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+ Sbjct: 15163 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15221 Query: 576 EDHGTYTCLAENALG 590 D G YT A N G Sbjct: 15222 RDSGAYTLTATNPGG 15236 Score = 32.3 bits (72), Expect = 4.6 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584 G + + + G P+P++T +G P++ AE +++++++ D G Y Sbjct: 20186 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20245 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635 A N+ G + V ++ P PT P+ + +++ V Sbjct: 20246 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20292 Query: 636 DGSQVT 641 GSQVT Sbjct: 20293 GGSQVT 20298 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P + L+ +K G+ V + +SG P P + W + E+Q + E S Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20624 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 + I++ ++G Y + N+ G A + VQ Sbjct: 20625 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20656 Score = 32.3 bits (72), Expect = 4.6 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 +P + + + G + + G P P +W G + R ++ + L I Sbjct: 23438 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23496 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 D G+YT E N +G T+++ + Sbjct: 23497 TIRDTGEYTLELKNVTGTTSETIKVII 23523 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 1811 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + D Y+C V T TA+LIVE Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%) Query: 1745 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1797 W K G V+ I + S M +I ++ K G+ + + A L + VS + Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399 Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 + + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1870 ++R L +V G R + G P P+V W K D +R+ Q+D D L+I Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12361 Query: 1871 DVCGDDDAKYTCKAVNSLGE 1890 + DD KY+ VN GE Sbjct: 12362 NSTRDDSGKYSLTLVNPAGE 12381 Score = 32.0 bits (71), Expect = 6.0 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786 R++ G S+ I I G P P V W +D L K+ + E N + FT L++ + Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14534 Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819 + G++ + ++N G+ S V++ + ++ L Sbjct: 14535 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14567 Score = 32.0 bits (71), Expect = 6.0 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 +D+ VV G + I G P P+VVW KD + + E+ +L++ D Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468 Query: 1875 DDDAKYTCKAVN 1886 D +Y K N Sbjct: 18469 TDGGQYILKLSN 18480 Score = 32.0 bits (71), Expect = 6.0 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104 K G+ + + G P P+VTW + R + + +L + D G+Y Sbjct: 22355 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22413 Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164 N +G + +V + V G G VS + E+ WGE Sbjct: 22414 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22465 Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215 T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+ Sbjct: 22466 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22518 Score = 31.6 bits (70), Expect = 7.8 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E S R I+G P P V W K + + ++ N +LI+ D D KYT Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13749 Query: 1882 CKAVNSLG--EATCTAELI 1898 N G E T + +++ Sbjct: 13750 ITLKNVAGTKEGTISIKVV 13768 Score = 31.6 bits (70), Expect = 7.8 Identities = 19/80 (23%), Positives = 30/80 (37%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V +T ++ G P P+V W +G + +E+ L + D G Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y SN G S T++V Sbjct: 18474 YILKLSNVGGTKSIPITVKV 18493 Score = 31.6 bits (70), Expect = 7.8 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694 G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y Sbjct: 18417 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475 Query: 695 CEAWNSAG 702 + N G Sbjct: 18476 LKLSNVGG 18483 >gi|110349713 titin isoform novex-1 [Homo sapiens] Length = 27051 Score = 366 bits (939), Expect = e-100 Identities = 238/812 (29%), Positives = 389/812 (47%), Gaps = 79/812 (9%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154 AP FK++L++++V L C+V+ P + W GK + K+ I +G Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + I +D +Y+ A N G + + V+ Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24648 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 P K +P + +R GE V + +G TW K Sbjct: 24649 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24692 Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 + I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP Sbjct: 24693 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24752 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393 P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V + Sbjct: 24753 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24811 Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453 L Y+FRV A N +G S+PS+ SE T E + E D+ EV + Sbjct: 24812 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24868 Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513 ++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+ Sbjct: 24869 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24927 Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573 N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E + Sbjct: 24928 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24987 Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633 +++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV Sbjct: 24988 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25047 Query: 1634 NYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAK 1693 ++ + ATDMWS+G + Y+L+SG++PF+ + + + + N+ +A + FD+EAF EIS +A Sbjct: 25048 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25107 Query: 1694 DFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1753 DF+ LL K+ K+R+ ++ LQHPWL + + + K + + ++Y +K N V Sbjct: 25108 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25166 Query: 1754 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1813 + R+S I +S G + + +E VS + AV EE HVK Sbjct: 25167 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25214 Query: 1814 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 + CKIE Y +V W+ + + S ++I Y EDG L + D+ Sbjct: 25215 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25259 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 DD Y CK VN GE + AEL V+ + E Sbjct: 25260 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25291 Score = 164 bits (416), Expect = 6e-40 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%) Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122 +VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++ Sbjct: 26376 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26435 Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171 + S K+ Q T+ + A E S P T L Sbjct: 26436 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26490 Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y Sbjct: 26491 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26550 Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285 TC V N +G S S +L+I+ + V K + + V++E++ + ++ Sbjct: 26551 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26610 Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 EA ++ SK S + S + +K + RT + Sbjct: 26611 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26670 Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388 T SI + R+ + G GV + EE + T +Q Sbjct: 26671 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26728 Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440 + + +SK + + + S P F S+P+SQ + E Q V F CE+SG Sbjct: 26729 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26788 Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS Sbjct: 26789 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26845 Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560 T + L ++E PS VL+ D LQ S + Q +Q + S Sbjct: 26846 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26887 Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613 EA + A + ++ ++ ++S S+++ + S + Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 26947 Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671 A + P SD+ + +G +T+ +G P PEV W G +I QE FH Sbjct: 26948 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 27007 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 E +L I +V +D G YT N G Sbjct: 27008 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27038 Score = 144 bits (364), Expect = 6e-34 Identities = 102/320 (31%), Positives = 157/320 (49%), Gaps = 23/320 (7%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P+ + Q V+ + +F +SG P+P+++W+ E + + D + L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526 L++A D+ Y+C A N G + S +L VE V+ P+ + L+D Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311 Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583 EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370 Query: 584 LAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAPSKPTA---PIFLQGLSDLKV 634 +A NA+GQVS +A +++ E S+ + L V+ K P F+Q LS L+V Sbjct: 3371 VASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFPEDTGT 692 +G V +VSG P PE+ W HN I ++D FHFE+ + I + + E G Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490 Query: 693 YTCEAWNSAGEVRTQAVLTV 712 Y+C+A NSAGE A LTV Sbjct: 3491 YSCKAANSAGEATCAATLTV 3510 Score = 143 bits (360), Expect = 2e-33 Identities = 126/488 (25%), Positives = 194/488 (39%), Gaps = 100/488 (20%) Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKART 479 Q E Q +F+C VSG +V+W+ + ++ + +ED ++ L + +A Sbjct: 3306 QDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED--TYQLEIAEAYP 3362 Query: 480 RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEV----------------------APSFS 517 D GTY+ ASNA GQ+S + L +E + E PSF Sbjct: 3363 EDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFI 3422 Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQD 572 L V G+ V G P P I W N Q I + G+A + I D Sbjct: 3423 QPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVD 3482 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV---------HEK-------------------- 603 A E G Y+C A N+ G+ +C+A +TV HE+ Sbjct: 3483 AYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAE 3542 Query: 604 ---------KSSRKSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMT 643 + S+ +E L PV P+K T PIF++ +S+ + G T++ Sbjct: 3543 EEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3602 Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703 V V G P P++ W NG + S D+ F G HSL I ED G YTC A N G+ Sbjct: 3603 VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3662 Query: 704 VRTQAVLTVQ---EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCA 743 A L + E H T+ P F+ + + + + G + Sbjct: 3663 TICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYT 3722 Query: 744 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 803 + G+P PTV W ++ K LC + + T ++ Q +G Y +N +GE Sbjct: 3723 VVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3782 Query: 804 SCQVSLML 811 +C L++ Sbjct: 3783 TCAAELLV 3790 Score = 139 bits (349), Expect = 3e-32 Identities = 149/661 (22%), Positives = 246/661 (37%), Gaps = 102/661 (15%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ VA + S +L V+ E P + + + ++ G A+F + G P+ Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221 Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P+++W++ Q +++G + FL D ++L++ ED YTCEA N G + Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 L+VE P V + PP T L V EGQ R Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F C+++G +V+W + ++PS +++ LEI +D G YT + N Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376 Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE---------SKLDSLEA 290 G+ S +A LS++G E +NS ++ KE L SL Sbjct: 3377 GQVSSTANLSLEGFSKF------EENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430 Query: 291 AAKSKNCSSPQRGGSP----PWAANSQPQPPRESKLESCKDS------------PRTAPQ 334 + G P W N Q P + + ++S A Q Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490 Query: 335 TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQD 393 S+ AA + P+AP + +E + ++F + GL S + Sbjct: 3491 YSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3550 Query: 394 VVSKAANRRIPM-----------EGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPK 442 + N + + + +++ P F + + ++ V GIPK Sbjct: 3551 LQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPK 3610 Query: 443 PEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502 P++ WF G + + D H L +L + D G Y+C ASN G+ CS L Sbjct: 3611 PKIQWFFNGV-LLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 3669 Query: 503 QVE-----------RLAVME--------VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 ++ AV + P F LK +G + + +V G P P Sbjct: 3670 KINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAP 3729 Query: 544 RITWLLNGQ----PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 +TW + + Y G + D ED G Y C AEN LG+ +C+A + Sbjct: 3730 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3789 Query: 600 V 600 V Sbjct: 3790 V 3790 Score = 134 bits (336), Expect = 1e-30 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%) Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 S + P + S+ P + Q V + KF + +G P+P W +G + Sbjct: 26462 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26521 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++ Sbjct: 26522 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26570 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 +KD E Q Q + TP + ++ + Q A + E ++E Q+ L Sbjct: 26571 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26622 Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631 ++ + ++E + S + VHE+ K+S+ SE + A K + + Sbjct: 26623 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26675 Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G Sbjct: 26676 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26733 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751 TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P Sbjct: 26734 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26792 Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 + W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+ Sbjct: 26793 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851 Query: 812 QNSSARALPRGREPA 826 LP EP+ Sbjct: 26852 -------LPLVEEPS 26859 Score = 122 bits (306), Expect = 3e-27 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++ Sbjct: 23779 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23835 Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848 +L+N+ G+ + + + + S P G P +D+ V AD GG+D G Sbjct: 23836 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23891 Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906 + W + VRG +++ E R Q L + V+ Sbjct: 23892 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23949 Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963 KT L+ + P E +D + + + +V + ++ + K + Sbjct: 23950 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24008 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022 KT + + PD + ++ A+N +ET A + V P G Sbjct: 24009 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24064 Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070 L+ + +K + TL KP K D K ++KE +K Sbjct: 24065 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24124 Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120 +N+ R T + K + G AP +++++DV G+ L CQ Sbjct: 24125 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24183 Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180 + P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E Sbjct: 24184 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24243 Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240 S ++ + P P P K Sbjct: 24244 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24263 Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299 E G ++ L G TW +K +Q SE++ +EN+E+ + L + Sbjct: 24264 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24319 Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG Sbjct: 24320 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24379 Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P + Sbjct: 24380 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24439 Query: 1418 ESELTTVGEKPEEP 1431 S + + E+P Sbjct: 24440 VSSVVIIKSPFEKP 24453 Score = 118 bits (295), Expect = 6e-26 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%) Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680 T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714 I+E F ED+G +TC A N AG V T L VQ Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014 Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759 P + P+FI+KP G SV+ C + G+P P V+W + G Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074 Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ + Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131 Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875 L + ++ + V + G PG+ + + E+E + + K Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186 Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932 V R + E+ QE F + L K++ KT E+ L+E E+M + Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242 Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981 V+ S + ++ + + ++ V S P+P +++ + DF Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298 Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035 R+ L LP + G +A N K NA SG P P+G TL Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350 Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095 +P+ + +L P ++ + A + + + S+ + Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407 Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152 P F K EG+ +V P W +G+ + T +++ ++G+ Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212 S+ I A P D G + VA+N AG++ S +TV+ Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504 Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272 + + P ++ ++ ++ G +E+ + TG W+ Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544 Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327 K I ++ +++E ++ + L I + + YT NK G + + +VN+ V Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604 Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348 +P+P P GT A +I + L Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631 Score = 115 bits (288), Expect = 4e-25 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483 + E Q + + ++G +V W L G + E Y +GS +K A RD G Sbjct: 26678 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26733 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 +C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P Sbjct: 26734 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26791 Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 I W N PI + + V L I++A D G YT A+N GQ S +A + V Sbjct: 26792 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 LP+ +P+ + L+ D + GS + +VQ+S + + Sbjct: 26852 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26897 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 + + F Q +QE F E + + N ++ + ++ G Sbjct: 26898 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 26956 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779 P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL Sbjct: 26957 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 27016 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813 ++ VQ G Y + L N G S V++ +++ Sbjct: 27017 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27050 Score = 115 bits (287), Expect = 5e-25 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%) Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222 F +++ + EG F CK++G P P++ W K R+ E+ M L+ Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297 Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282 G+AS+ + + + +F K N I Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330 Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342 KL +E AA G+P + +P S++ S SPR+ ++P+ Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369 Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402 R+ P +P R PA PA PG ++ R Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408 Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 P F KP S + E QT +F +V G P PE WF +G + Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522 V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+ Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577 + EG ++ G P P I WL N P +Y + E G A L I + +D Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578 Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617 YT A N G+ C V V + + + ++P AP Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638 Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662 K P F + L+ L++ +++ G+P V WLH+G Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714 ++ + SL + D+G TC A N G T A L V++ Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758 Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744 H+G +P + P V G++ C + Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876 Query: 805 CQVSLMLQNSS--ARALPRGREP 825 +V L +Q L R EP Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899 Score = 113 bits (282), Expect = 2e-24 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 +K S RK E L + AP + +V G + V P EV W HNG Sbjct: 25981 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26040 Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682 E+QES D H + GT ++C Sbjct: 26041 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26100 Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718 + VFPE T T EA +S EV++Q T + H Sbjct: 26101 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26160 Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752 + ++KPRS+T G+S SC G+P PTV Sbjct: 26161 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q Sbjct: 26221 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279 Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848 + + ++ R + P +++ Sbjct: 26280 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26339 Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 L P + +L+ E +++ VL+ + T + +++ Q + Sbjct: 26340 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399 Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954 ++ L+E D + EI E + NLQ + K++ E+ K+ ++ D + Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459 Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983 S + +K K P P P P+P T D ++ Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519 Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015 + GGK KL + G SS+ L KA++ ++ Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26579 Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067 + Q + + P A E + A +E +K M AK E L + ASK EE+ Sbjct: 26580 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26636 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 KK + H T + SE T K + + EG++L+L+ ++ Sbjct: 26637 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26694 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W LNG L ++ GS +++I++A D G+ C++K G +C +T+ Sbjct: 26695 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247 + E+ SDA P I P Q Sbjct: 26755 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26771 Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 + G++V +++G W K I S ++ + S N L I A G Sbjct: 26772 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26831 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S Sbjct: 26832 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26891 Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423 + S++ + + + S + Q + E + + + G S +Q S++ Sbjct: 26892 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26949 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447 G + PK E SD E +V Sbjct: 26950 AGIRGIPPKIEALPSDISIDEGKV 26973 Score = 112 bits (279), Expect = 5e-24 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99 +N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311 Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155 D G YT A+N G + +L VE A LG P TL R +P +R I Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369 Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179 P F K EGQ R Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429 Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238 F K+ GRP P+ W G + V +++G Q L I D G +T + N Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489 Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297 +G++S+S L+++ ++ FV + K N I + S+L+ A + N Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538 Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339 W NS P + ++E K + V Q Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592 Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395 T + ++ +PEP ++ P G R K A P P Q D+ Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453 K ++ P F+ K S +K F C ++ G P V W +G P Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698 Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502 + + + + G L A +RDSG +C A+N G S TL Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757 Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536 ++E L M + + V D V+EG+ +C Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817 Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594 V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G + Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877 Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + + +++ R +L AP +P + G +V + T + E Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929 Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694 V+ L I +ESE+ F++R + S E + E Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738 E + E+ + + E T P F + +S T G Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049 Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798 + G P P W ++G + + + ++V LV++ V + + N Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109 Query: 799 RVGECSCQVSLMLQ 812 GE S L++Q Sbjct: 2110 IAGETSSHAFLLVQ 2123 Score = 111 bits (278), Expect = 6e-24 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 +PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L Sbjct: 12526 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12584 Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355 I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+ Sbjct: 12585 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12644 Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE Sbjct: 12645 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12704 Query: 1415 PSQESELTTVGE--KPEEPKD 1433 P ++ P EPK+ Sbjct: 12705 PLTSPKMVAQFPFGVPSEPKN 12725 Score = 110 bits (275), Expect = 1e-23 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567 AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+ Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I + G Y+ A N GQ + +A + V K+E AP P F+Q Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168 Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713 ED+GTY+ A NS G + A L VQ Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 109 bits (272), Expect = 3e-23 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%) Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89 T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58 Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144 S L I AV + + G+Y+ +ATNGSG T EL V+ A Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PP F +L + V++G R ++TG P P V + + +Q S Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252 +S++ + L I +D G Y+ N G+A+ +AEL +QG Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207 Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + +A S R+T+ + + ++ + E +D AA + +P R PP + Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263 Query: 312 SQPQPP 317 P PP Sbjct: 264 RSPTPP 269 Score = 109 bits (272), Expect = 3e-23 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7389 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y + Sbjct: 7390 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7448 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426 E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T + Sbjct: 7449 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7508 Query: 1427 KPEEPKDEVEVSD 1439 P P +E SD Sbjct: 7509 DPPGPPTRLEPSD 7521 Score = 106 bits (264), Expect = 2e-22 Identities = 102/414 (24%), Positives = 158/414 (38%), Gaps = 48/414 (11%) Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 +F + +V E + F CEVS P V W + ++ + I++ ++ H L + Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 R D+G Y+ A + +L V S+ K+ VIE Q V++ Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121 Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 V V W +G I + + E + + I + D G YT +A Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 +R S L AP P LQ L + V G +SG Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P P++ W + F G +++L + E FPED YTCEA N G T A Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279 Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 L+V+ P D P + I+ + S GQ C ++G + +D K Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815 K + F + Q ED + L + + P G Y + N VG+ S +L L+ S Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFS 3391 Score = 102 bits (253), Expect = 5e-21 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 +++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A Sbjct: 20504 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20563 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG Sbjct: 20564 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20623 Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 + + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP Sbjct: 20624 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20680 Query: 1417 QESEL 1421 + + Sbjct: 20681 ESDSV 20685 Score = 101 bits (252), Expect = 6e-21 Identities = 114/459 (24%), Positives = 183/459 (39%), Gaps = 56/459 (12%) Query: 384 TRQPGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP 441 TR G VV+ + ++ +EG RD + + Q E K+ V+F + Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAKLFVEG-RDVRIRSIKKEVQVIE-KQRAVVEFEVNEDDV- 3129 Query: 442 KPEVAWFLEGTPVRRQEGSIEVYE-DAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 + W+ +G + Q Y + H + + + R D+G Y+ A G+ S Sbjct: 3130 --DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSV 3183 Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--- 557 TL V P L+ V G+ + G P P+I+W Q + Sbjct: 3184 TLYVNA----PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 + + L + +A PED YTC A+N G + SA ++V E + +PV P Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMPVYP 3298 Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677 P + L D +G +VSG +V W +I+ S F Q Sbjct: 3299 -----PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDT 3352 Query: 678 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ------------------------ 713 + L I E +PED GTYT A N+ G+V + A L+++ Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKK 3412 Query: 714 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKD-TGHFEV 770 EP G +P FI S+ G++V ++G P P + W + + + KD HFE Sbjct: 3413 EPL-GQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE- 3470 Query: 771 LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 ++ + +++ HAGQY N GE +C +L Sbjct: 3471 -ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATL 3508 Score = 101 bits (252), Expect = 6e-21 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%) Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292 +PP + ++ E V+AG +V + G T W +I+ EH VE Sbjct: 11134 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11193 Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352 S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11253 Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411 DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G Sbjct: 11254 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11313 Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469 P +S T K P P + V+D E V + + ++ +Y +E R Sbjct: 11314 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11371 Query: 1470 LGSGKFGQV 1478 +GK+ +V Sbjct: 11372 EVTGKWVRV 11380 Score = 101 bits (252), Expect = 6e-21 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++ Sbjct: 16168 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16224 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL Sbjct: 16225 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16284 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16344 Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432 YG EP + + P+ PK Sbjct: 16345 YGVGEPLESEPVVAKNPFVVPDAPK 16369 Score = 101 bits (251), Expect = 8e-21 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%) Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302 F + VRAG S+ LF G T W K + S + +++ S LT+ + Sbjct: 21991 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22048 Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362 G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+ Sbjct: 22049 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22107 Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421 + Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E Sbjct: 22108 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22167 Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471 E+P P+ D V+ S +P+ D + QK SDF+ +E Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22226 Query: 1472 SGKFGQVFRLVEK 1484 V RLVEK Sbjct: 22227 KQLTFTVERLVEK 22239 Score = 100 bits (250), Expect = 1e-20 Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%) Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119 +V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG + Sbjct: 4396 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4452 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 +LTV A PV+ + K+ + V G + + Sbjct: 4453 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4480 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F+C+I P + W K + S + S+ + LEI D G YTC N Sbjct: 4481 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4540 Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294 G S +A L ++ G + R + E K + ++EV +V+ K + + + K Sbjct: 4541 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4597 Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354 + P PP P+P E ++ + R P+ + + +I L A +P Sbjct: 4598 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4651 Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414 +P A + P E P P T P ++ +AA + P++G Sbjct: 4652 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4710 Query: 415 KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441 E+ +P S K F ++ +P Sbjct: 4711 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4770 Query: 442 KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P A W +G+ + R+ D L ++ + D+G Y+C + + Sbjct: 4771 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4829 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 + L VE L V V ++ ++ V++GQ L C + + W +G+ + Sbjct: 4830 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4883 Query: 559 STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 GV L I DA D GTYT ENA + CS+ V V E Sbjct: 4884 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4930 Score = 100 bits (250), Expect = 1e-20 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 ++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L + Sbjct: 15093 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15152 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG Sbjct: 15153 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15212 Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 + + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP + Sbjct: 15213 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15272 Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471 + V P+ PK+ EV D P+ D + IN Y +E R Sbjct: 15273 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15322 Query: 1472 SGKFGQVFRLVEKKT 1486 K GQ + KKT Sbjct: 15323 -DKAGQRWIKCNKKT 15336 Score = 100 bits (249), Expect = 1e-20 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y Sbjct: 15787 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15846 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y + Sbjct: 15847 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15906 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 E D++ TW+ + AT T+ L EY+FR+ A N YG S Sbjct: 15907 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15952 Score = 100 bits (248), Expect = 2e-20 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%) Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567 V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623 L I LPED G YT A N G CS + V Y L PV+ + +P Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362 Query: 624 -------------------------------------------------IFLQGLSDLKV 634 +F+ K Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 ++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 +T A N AG +LTV+ +P F+ K ++V G + + G+P P + Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541 Query: 753 HWLRD 757 WL++ Sbjct: 1542 VWLKN 1546 Score = 100 bits (248), Expect = 2e-20 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A++ S +L +V +PL FI P ++ + E AKFE V P+ Sbjct: 5446 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5496 Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114 W + Q IT RF L+ G + + + A +E + + E + SG Sbjct: 5497 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5555 Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144 + VT + F +L + KT F Sbjct: 5556 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5615 Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190 +++ I E P F KL E C+I+ P Sbjct: 5616 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5675 Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248 V W K ++PS + ++L + + D+G YTC G+ K S ++ Sbjct: 5676 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5732 Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287 S++ +++ F ET+ + D+ + I +E K+ S Sbjct: 5733 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5790 Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341 L NC Q GG AAN + K L KD TA +T Sbjct: 5791 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5846 Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395 S L+ +++P + + P E + R + G + Sbjct: 5847 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5896 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 +K + + +F + Q V+E T CEVS +V WF GT + Sbjct: 5897 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 5953 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 + + E+ D L + D TY+C A + + SC+ L V+ Sbjct: 5954 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 6003 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572 F L D V E + +C + ++ W +G I+ + + V L I Sbjct: 6004 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6062 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632 L +D Y+C A S +TV E+++ +F + L+++ Sbjct: 6063 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 6100 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 +V + + + +VS P EVIW EI E+ + G + L IQ ED G Sbjct: 6101 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6159 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 Y C +S RT + V E FISKP+++ G+ C+I+ + FP V Sbjct: 6160 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6210 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796 W RD K L + ++V+ + LV+K G Y +++ Sbjct: 6211 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6253 Score = 100 bits (248), Expect = 2e-20 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288 MPP I E +V G +V + K+ G T TW K ++ + H+ Sbjct: 9744 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9802 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348 ++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + + Sbjct: 9803 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9862 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407 TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A Sbjct: 9863 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9922 Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 N YG EP + +PE ++ V + D V ++T+N E+ D Sbjct: 9923 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9971 Score = 99.8 bits (247), Expect = 2e-20 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%) Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343 E + +K PQR S P +P P E+ +++ ++KT+ Sbjct: 693 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750 Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403 T + V PR SP K P G + ++ +A + Sbjct: 751 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796 Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463 E S+ K ++ VK ++T R P P+ F + + E +EV Sbjct: 797 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852 Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523 ++ G + + R+ A+ + VE + P+ S LK+ Sbjct: 853 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580 VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G Sbjct: 907 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966 Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614 +TC A N G VS S ++ V EK+++ +E Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026 Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671 P +P AP F+ K+++G V QV GNP P V W +G + + + Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 ++ + L I F +D G YT N GE A L + ++ Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132 Score = 99.4 bits (246), Expect = 3e-20 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++ Sbjct: 17251 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17307 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351 + L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+ Sbjct: 17308 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17367 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410 W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y Sbjct: 17368 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17427 Query: 1411 GTSEPSQES 1419 G EP + + Sbjct: 17428 GVGEPLESA 17436 Score = 97.8 bits (242), Expect = 9e-20 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%) Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +E VK+ C++ + +V W+ + E YED G L + D GT Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25266 Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522 Y C N G+ S C T++ + + ++E P F+ L + Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25326 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576 G++ ++ P P +TW +GQ I+ + + G+ +L I + Sbjct: 25327 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25386 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 D YT +A N G+ SC A +TV L P P+F + L++ + + Sbjct: 25387 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25436 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695 G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y Sbjct: 25437 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25496 Query: 696 EAWNSAGEVRTQAVLTVQ 713 A N+AG QA L V+ Sbjct: 25497 TATNTAGSTSCQAHLQVE 25514 Score = 97.4 bits (241), Expect = 1e-19 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y Sbjct: 21203 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21262 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T++++N + + + + P P G +I++ S+ LSW +GG + YSI Sbjct: 21263 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21322 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P Sbjct: 21323 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21370 Score = 97.4 bits (241), Expect = 1e-19 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26061 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278 + DD G Y + N G+AS A L + G D + R + V E+T Sbjct: 26062 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26121 Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 +S K +EA++ + S + + S + ++++S ++ + Sbjct: 26122 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26178 Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396 +K +++ AAR+ +PR+ + GE + PT L V+S Sbjct: 26179 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26230 Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450 +A ++ + + + S S E V EN K E + I K V Sbjct: 26231 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26288 Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509 +P R + V +K+ R S S + + + + T +V+ L V Sbjct: 26289 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563 P + LK A + L C V + + +TW +G+ ++ + Sbjct: 26343 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399 Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609 G EL I + D G Y C G Q A+ ++HEK KS +K+ Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459 Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 ++P AP + + GL D V S V+ +G P P IW +G Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 I + + + L I + D+G YTC NSAG V + LT++ D Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26574 Score = 96.7 bits (239), Expect = 2e-19 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y + Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13053 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 + +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P Sbjct: 13054 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13101 Score = 96.7 bits (239), Expect = 2e-19 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%) Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64 K + I+KTS + + R + E AF + I EG + + G + V Sbjct: 26646 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26696 Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 W NG +T+ + G+ G+ +L I D G TC + G + +LT+ Sbjct: 26697 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754 Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183 SK L D APA ++P + EGQ F+C+ Sbjct: 26755 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26784 Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243 I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S Sbjct: 26785 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26844 Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301 +A L + L V + V+ + S SL+ +++S S+ + Sbjct: 26845 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26887 Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361 + S ++S E K S ++ Q ++ +SSS + Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26932 Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421 G+ + + E S + KA R IP PK E+ P Sbjct: 26933 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26964 Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480 + E + + C +G P PEV W G + QE G + L ++ + + Sbjct: 26965 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 27024 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507 D G Y+ + N G S + + + + Sbjct: 27025 DGGLYTLSLGNEFGSDSATVNIHIRSI 27051 Score = 96.3 bits (238), Expect = 3e-19 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%) Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P T PP + + F + +R GE+ L G+ +G +W K + E + + Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346 + + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++ Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405 + +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+ Sbjct: 10556 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615 Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431 A N+YG S+P + V + P++P Sbjct: 10616 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10646 Score = 95.9 bits (237), Expect = 3e-19 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%) Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +G + + + K P P I D V GE + + T +W K Sbjct: 7994 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8110 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392 ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+ Sbjct: 8111 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8169 Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449 DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + + Sbjct: 8170 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8228 Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474 + + K+ + I E++ G+ Sbjct: 8229 KPPLYDGGSKIMGY--IIEKIAKGE 8251 Score = 95.9 bits (237), Expect = 3e-19 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%) Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561 ++A +E+ P ++ EG C + ++TW + ++ + T Sbjct: 25189 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25247 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608 E GVA L+++D D GTY C N G+ S A + V KK R+ Sbjct: 25248 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25307 Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667 ++ + L P + T P++ + G V V ++ +P P V W +G +I+ + Sbjct: 25308 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25362 Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720 + + FE + L I V +D YT A N GE +A LTV P D T + Sbjct: 25363 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25422 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F + GQSV ++G P PT+ W +DG+ L + + D + L Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 ++ P G Y + N G SCQ L ++ Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514 Score = 95.5 bits (236), Expect = 4e-19 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%) Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 ++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G Sbjct: 14018 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14077 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY Sbjct: 14078 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14136 Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q + Sbjct: 14137 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14193 Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 V P P ++ EVS+ V T T++ ++ V D Sbjct: 14194 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14226 Score = 94.7 bits (234), Expect = 7e-19 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S+ +F + G TW K I +EN+E+ + L I + G + Sbjct: 14416 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14473 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y + Sbjct: 14474 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14532 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E Sbjct: 14533 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14592 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478 P P D + + D + + + + K++ + +R GS ++ + Sbjct: 14593 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14642 Score = 94.7 bits (234), Expect = 7e-19 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++ Sbjct: 19414 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19470 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L Sbjct: 19471 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19530 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19590 Query: 1410 YGTSEP 1415 YG EP Sbjct: 19591 YGVGEP 19596 Score = 94.4 bits (233), Expect = 1e-18 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23143 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y + Sbjct: 23144 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23202 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E Sbjct: 23203 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23262 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P P ++EV D V TVT+ E+ + D Sbjct: 23263 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23289 Score = 94.0 bits (232), Expect = 1e-18 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19093 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y + Sbjct: 19094 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19152 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E Sbjct: 19153 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19210 Query: 1428 PEEP 1431 P P Sbjct: 19211 PFSP 19214 Score = 93.2 bits (230), Expect = 2e-18 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%) Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301 +AG + + + G +W K +K +++ H ++E +EN S + I + Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + H G Y++ +NK G + A + V+D P PP SDI S LSW DGG Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9569 Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 ++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + + Sbjct: 9570 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9629 Query: 1421 LTTVGEK--PEEPKDEVEV 1437 TT + P +P ++++ Sbjct: 9630 RTTARDPIYPPDPPIKLKI 9648 Score = 92.4 bits (228), Expect = 4e-18 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 + P F +L +K A FE R+ G P V W +G+P+ + R + G Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146 SL + D G TC ATN G + L V E S ++ P K L Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773 Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199 + ++ G + P V V EG+ RF C++TG PQP+V W Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 ++ S R V +G+ L+I D G N G +L IQ + RS Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891 Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318 +R + + E K+D ++K +R + Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951 Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378 SK + + T V K+ ++ + EE+K A Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 T PT +P +I + ++ PK + QSQ V + FR V Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 G P PE W+ G + R + + + L + DS + A N G+ S Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557 L V+ ++ +F+ L+D E P ++ W +G + Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172 Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 R + V L I D Y+C V V ++ ++ ++ Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218 Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672 A + F++ L D++V + + VS PE I W HN E++ + + Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269 Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694 R + +L +++V ED G Y+ Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291 Score = 92.4 bits (228), Expect = 4e-18 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290 P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++ Sbjct: 18333 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18389 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L + + G Y L + N G++ + + V+D+P PP G + + + L Sbjct: 18390 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18449 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N Sbjct: 18450 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18509 Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438 YG EP + +T KP P EVS Sbjct: 18510 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18539 Score = 92.4 bits (228), Expect = 4e-18 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 T + TV+ T + MP + I P AG VEL + G P +W Sbjct: 23351 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23404 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 +++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP Sbjct: 23405 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23464 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394 G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L Sbjct: 23465 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23524 Query: 1395 LPDHEYKFRVRAINVYG 1411 +EY FRV A N +G Sbjct: 23525 TEGNEYVFRVAATNRFG 23541 Score = 92.0 bits (227), Expect = 5e-18 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 +P+T P + +N+ + EG + E + GYP P VTW+R I S F + Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143 G L+I ED G++TC A N +G + L V+ S + V++ T R Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009 Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194 F S V T S+ E P F TK + EG F C++ G P+P V W Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069 Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 K VPL R VS +++ G L I DD G YT +V N G+ S SA L Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125 Score = 92.0 bits (227), Expect = 5e-18 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AGE V++ G P T TW K K + +EN+++ S LTI + G Y Sbjct: 20912 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20971 Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I Sbjct: 20972 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21090 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474 P P ++ + D + + + + ++++ + ER G G+ Sbjct: 21091 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21134 Score = 91.7 bits (226), Expect = 6e-18 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y + Sbjct: 16929 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16988 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 + D+ W + AT T+ V L EY+FR+ A N YG S Sbjct: 16989 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034 Score = 91.3 bits (225), Expect = 8e-18 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%) Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301 KV+AGE V + VTG W K I++ +V SE ++L+I A Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 +E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS Sbjct: 9097 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9155 Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418 + Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ + Sbjct: 9156 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9215 Query: 1419 SEL 1421 ++ Sbjct: 9216 DKV 9218 Score = 91.3 bits (225), Expect = 8e-18 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%) Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282 P P PP++I +Q ++ G+++ L + G TW K + Sbjct: 10832 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10891 Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342 + V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+ Sbjct: 10892 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10948 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401 IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y Sbjct: 10949 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11008 Query: 1402 FRVRAINVYG 1411 FRV A N YG Sbjct: 11009 FRVAAENQYG 11018 Score = 91.3 bits (225), Expect = 8e-18 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%) Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PKA +PP+I + +KV RA ++ LF + G W R + + Sbjct: 15477 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15534 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 +E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++ Sbjct: 15535 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15593 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV Sbjct: 15594 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15653 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A N YG P++ +E E+P P Sbjct: 15654 LAENEYGIGLPAETAESVKASERPLPP 15680 Score = 90.5 bits (223), Expect = 1e-17 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%) Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 V AG + + V+G P T TW M R QE+ +E + S + I ++ H G Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10220 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10279 Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425 IE +S + W + T + VQ L+ Y FR+ A N G + SE + Sbjct: 10280 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10339 Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475 E PE P+D +EV EV TVT+ D Y +E RL G+ KF Sbjct: 10340 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10391 Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524 K T + + KE + +S +N + K C Sbjct: 10392 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10433 Score = 90.1 bits (222), Expect = 2e-17 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ LF + G W K +I+++ + V +S + L + + G Y Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16639 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y + Sbjct: 16640 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16698 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E Sbjct: 16699 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16758 Query: 1428 PEEP 1431 P+ P Sbjct: 16759 PQPP 16762 Score = 90.1 bits (222), Expect = 2e-17 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%) Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278 P P +++++P+ D++ + G V G + T PI C W K + I Sbjct: 23746 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23805 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G Sbjct: 23806 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23863 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397 DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L + Sbjct: 23864 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23923 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454 EY FRV A N +G S+P + E T PE P + EV D + + + Sbjct: 23924 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23983 Query: 1455 NTEQKVSDFY 1464 + +V+ +Y Sbjct: 23984 DGGSRVTGYY 23993 Score = 89.4 bits (220), Expect = 3e-17 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679 AP F Q L + V++GS T +SG P PEV W +G I S + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122 Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799 + + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 800 VGECSCQVSLMLQ 812 VG + L++Q Sbjct: 182 VGRATSTAELLVQ 194 Score = 89.0 bits (219), Expect = 4e-17 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%) Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467 Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+ Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846 Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527 G HYL ++ ++ D+G TA N +G + L++++ F SVL+ Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900 Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V LQ V+ P + L + I + + E+ EL + Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958 Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618 + G Y + E L + W E+K + E + + Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018 Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 KP AP + + V GS V+V G P PE W NG +I+ S+ Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078 Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728 + + L I++V ED+ + +A N AGE + A L VQ T F + + Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135 Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758 V A ++ +PF V W +DG Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165 Score = 87.8 bits (216), Expect = 9e-17 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%) Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285 PK + P I + VRAG + LF V G TW K +++ + Sbjct: 12225 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12281 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+ Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12340 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV Sbjct: 12341 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12400 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A+N YG P+ + + EP Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEP 12427 Score = 87.8 bits (216), Expect = 9e-17 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%) Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 P P P I+ PE + +RAG ++ L+ V G P TW K + Sbjct: 13303 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13362 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 ++ + +++++ + L + G Y L +EN G ++ + + V+D P PP Sbjct: 13363 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13421 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397 +I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L Sbjct: 13422 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13481 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428 Y FRV A N YG +P + + + P Sbjct: 13482 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13512 Score = 87.8 bits (216), Expect = 9e-17 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%) Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I + +KV RA ++ LF + G W K + ++ ++E + + + Sbjct: 18732 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18789 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW Sbjct: 18790 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18848 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG Sbjct: 18849 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908 Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P++ +E V E P P V +V T TI E+ SD Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18950 Score = 87.0 bits (214), Expect = 2e-16 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S + G TW R++ + ++ +++E N ++L+I + G Y Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17721 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I Sbjct: 17722 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17780 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 + +S K + +++ C TSF V++L Y FRV A N +G P + + E Sbjct: 17781 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17840 Query: 1428 PEEP 1431 P P Sbjct: 17841 PSPP 17844 Score = 87.0 bits (214), Expect = 2e-16 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 ++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y + Sbjct: 18011 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18070 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E D+ TW + AT T+ + L EY+FR+ A N YG S P Sbjct: 18071 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18118 Score = 85.5 bits (210), Expect = 5e-16 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472 P F QS V E T F +SG P PEV+WF +G + +++ G L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531 + +SG YS A+N GQ T E L E A P+F L+ V +G Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+ Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616 +G+ + +A + V E+ ++K++ ++ A Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211 Score = 85.5 bits (210), Expect = 5e-16 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+ Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I D G++T A N +G ++V LTVE AVE Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505 Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210 + P F KL V +KEG + TG P P + WLK + + P ++ + Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561 Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 G L+I D YT +N +G+ + +++++ Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602 Score = 84.0 bits (206), Expect = 1e-15 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%) Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 + G + +W K + + VE+S + L + ++ G YT+ ++N G+++ Sbjct: 13634 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 +++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W Sbjct: 13694 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13753 Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 A+ + T+F V L EY FRV A N YG E Sbjct: 13754 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13788 Score = 83.6 bits (205), Expect = 2e-15 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%) Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I FP VRAG ++++ ++G T + ++ + E + Sbjct: 20101 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20160 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 + + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W Sbjct: 20161 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20220 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G Sbjct: 20221 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20280 Query: 1413 SE 1414 S+ Sbjct: 20281 SD 20282 Score = 83.2 bits (204), Expect = 2e-15 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%) Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 P I++F + +++GES+ + V G TW K +I++ +M++ + + Sbjct: 21583 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21642 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W Sbjct: 21643 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21702 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G Sbjct: 21703 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21762 Query: 1413 SEP 1415 P Sbjct: 21763 GRP 21765 Score = 82.8 bits (203), Expect = 3e-15 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%) Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938 H EE+ QQ + +++ ++S ++E + PA + + + VKP+ + Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726 Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997 SE K + + S + K T V P+ A+P F K +P Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783 Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055 A + K LS + + + + A T+KP AE L A Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840 Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095 + KS + E+KK+V + GTT E+R E Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894 Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155 T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + + Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213 I +A ED G + C A N+AG SC V V + E T E + K + Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +D ++ ++ A P A P I P QK+ G SV +V G W K Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071 Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325 + KV N + G KL I + G YT++V NK G A +L Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125 Score = 82.4 bits (202), Expect = 4e-15 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%) Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457 ++G++ + K + +P Q+V E V+ +VS + E W +G V+ Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352 Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517 + + + D SH L + D+G YS T L S + +V +V + P Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404 Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574 LKD VIEG VL+C V V + W LN + I+ ++ + L I Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462 Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634 D G Y + +G+V + ++V + K ++GL DL Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694 + V V++S + +V+W EI+ S + E G + L + + +D G YT Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753 AGE T LTV ISKP T + Q + C +A +P Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605 Query: 754 WLRDGKAL 761 WLRDGK L Sbjct: 2606 WLRDGKHL 2613 Score = 82.4 bits (202), Expect = 4e-15 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%) Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144 D E R++ + AP K QD+ V GK L + + P A W + L T Sbjct: 6615 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6674 Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204 +++ S + +K D+G YK V +N G+AE + V D P Sbjct: 6675 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6719 Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264 PV E T + + ++ + G S ++ G V Sbjct: 6720 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6756 Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322 + I TW+ + + E + G + + + G + +N + +R Sbjct: 6757 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6816 Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W Sbjct: 6817 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6869 Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 T R+ S V D++ EY FRVRA N G +PS + V + E P V ++ Sbjct: 6870 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6929 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493 D+ + V + + I ER GK + +LV + T KV K Sbjct: 6930 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6989 Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516 + SA+ K + I+ L Sbjct: 6990 YLYRVSAENKAGVSDPSEILGPL 7012 Score = 82.4 bits (202), Expect = 4e-15 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG S + G W K ++ + V+ +++ + LTI A + G Y Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19883 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I Sbjct: 19884 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19942 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E +++ K W + C S+ V +L Y FRV N +G P++ E + EK Sbjct: 19943 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20002 Query: 1428 PEEPK 1432 P P+ Sbjct: 20003 PSPPE 20007 Score = 82.4 bits (202), Expect = 4e-15 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G Sbjct: 24535 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24594 Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 EI + + ++ +G H L I V +D Y A N G V A L V+ P Sbjct: 24595 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24654 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L Sbjct: 24655 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24713 Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801 V V+ AG Y + KNR G Sbjct: 24714 VFPNGVERKDAGFYVVCAKNRFG 24736 Score = 82.0 bits (201), Expect = 5e-15 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%) Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78 R D+M L E P F LP N G +F + +PEP VTW+++GQ I G + Sbjct: 25307 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25366 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + + +G + L I++V +D +YT A N G +LTV L P Sbjct: 25367 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25419 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 TL P F L +EGQ F +++G P P + W K Sbjct: 25420 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460 Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257 PL + + E L I +D G Y N +G S A L ++ L Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520 Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290 + F + + V+K++ + L E+ Sbjct: 25521 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25552 Score = 81.6 bits (200), Expect = 7e-15 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306 V+AG+++ L V G W K + + S +K++ + SK ++ A++ G Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11900 Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y Sbjct: 11901 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11959 Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423 +E ++ W AT + V L+ +EY FRVRA N GT P++ + T Sbjct: 11960 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12019 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464 +KP P D EV+ ++E V + + + ++ ++ Sbjct: 12020 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12059 Score = 81.6 bits (200), Expect = 7e-15 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 + ED G YTC A N GEV T + L +Q P + K + A +G ++ + Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24277 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800 G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N Sbjct: 24278 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336 Query: 801 GECSCQVSLMLQN 813 G + + +Q+ Sbjct: 24337 GTVDAILDVEIQD 24349 Score = 81.3 bits (199), Expect = 9e-15 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%) Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L + Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 L T D+ YSC + + + +L V F L+D V E L+ Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241 Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 C V + W N ++ T G L ++D ED G Y+ + + Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 KK++ K + KP LQGLSD KV +G V + V+VS Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338 Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707 E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397 Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 +V I+ + V G ++ C ++ +V W + + + K Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444 Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 + + LV+ + G Y++++ RV E +C +S+ Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484 Score = 80.9 bits (198), Expect = 1e-14 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 + E ++ F E+S P W L+G + R + E+ + G +L L K + +G Sbjct: 5036 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 5093 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 A NA + L V E+ F+ LKD V E + +C + T Sbjct: 5094 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5142 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601 + W I+ + + HI D+ +D G YT E + S +VT Sbjct: 5143 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5200 Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 K F+ L D V +G T ++S + V+W N Sbjct: 5201 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5239 Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721 ++ S G H L ++EV +D + E+ + A L V E P Sbjct: 5240 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5291 Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781 +F K TA + + C ++ D V W +DG+ + + + + L + Sbjct: 5292 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5348 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837 KK G+Y C C N + A L + +P ++ G Sbjct: 5349 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5399 Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889 + D +G W +GQ D E + K + T + + +A Sbjct: 5400 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5455 Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949 + L ++L + LS D+K ++ F + R+ PKT R + Q Sbjct: 5456 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5505 Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007 ++ D R L K GT + V + A F + + +G E + K Sbjct: 5506 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5559 Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067 + K ++ + + V + +K N + T + + + + + S + ++L Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5618 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 D + + + G + K + +G P F KLQD E +++LQC++S A Sbjct: 5619 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5674 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ + Sbjct: 5675 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5730 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 +D E+K RP S+ V+ TE+ Sbjct: 5731 EDR---------EIKLVRPLHSV-EVMETET 5751 Score = 80.9 bits (198), Expect = 1e-14 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PPKA + ++ + +RAG + L V G W K K++ E + ++ + Sbjct: 22671 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + I + G YTL V+N G++ V + V+D P P G S + TL Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22787 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N Sbjct: 22788 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22847 Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433 YG SEP T+ P P++ Sbjct: 22848 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22876 Score = 79.7 bits (195), Expect = 2e-14 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AG+++++ V G T TW K + +++++ + E + + L I + G Y Sbjct: 14706 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14765 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 L N +G + + V D P PP G ++ S +T SW DGG + +Y +E Sbjct: 14766 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14825 Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411 + + + TW ELA T T++ L EY+FRV+A N YG Sbjct: 14826 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14868 Score = 79.3 bits (194), Expect = 3e-14 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Query: 1789 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848 EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD + Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284 Query: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336 Score = 79.3 bits (194), Expect = 3e-14 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%) Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80 P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079 Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140 LVI V ED +A N +G L V+ AKQL Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127 Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199 F +L VV KE M F C+ T P +V W K + Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 + + + + L I ++ D Y+C++V +A+L ++G A Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222 Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312 FV+E + E+ ++S E+ + +E + K + +RG + Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282 Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363 + E K +CK + P +LQ S + VQ E + GV Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341 Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420 G+E +P+ + L +D+ + A IP G S S Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400 Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 +K+ ++ C+VS V W+L + + + ++ L + Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 + D G Y G++ + L VE++ ++ L+D E Q+ V + Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508 Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592 + + + + W + I+ + + + +L + + + +D G YT A G+ Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563 Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652 S +TV A SKP L+D V + + +V+ NP Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602 Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + WL +G + + + E G + L I +D G YT + S +T A L V Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658 Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 + I K +++T + Q + + + V W+++G L Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701 Score = 79.0 bits (193), Expect = 4e-14 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471 P+F ++ + V+F ++ P+P V W+ G ++ + + D G + Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528 L + T D Y+ A N G+ SC L V + P F +L + EG Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25437 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584 Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y Sbjct: 25438 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25497 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611 A N G SC A + V E+ +K E+ Sbjct: 25498 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25523 Score = 78.6 bits (192), Expect = 6e-14 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%) Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276 +P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K Sbjct: 8292 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8349 Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310 ++QE E + ++NS+ G S+L + + + G Y + Sbjct: 8350 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8409 Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370 VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E Sbjct: 8410 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8468 Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 D + W + +T R ++V L+ EY FRVRA N +G P L V + Sbjct: 8469 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8526 Query: 1428 PEEPKD 1433 P P D Sbjct: 8527 PFGPPD 8532 Score = 78.2 bits (191), Expect = 7e-14 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%) Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94 I P +++ + EG A E +V V W+ N + I R + ++GT LVI+ Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459 Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154 H D G Y G + L+VE Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487 Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214 K L + E Q F +++ V W + ++PS++ + Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272 + L + + +DD G YT +G+ S +L++ G + ++ +T A + + Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594 Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329 EV N SK L + + N S G A K+ + K S Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654 Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378 + + ++KT ++T+ + P G+ GV+ S E+ Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 + + + + V R + + K KP+ EN TV F VS Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P V WF + ++ + + + H L L D+G Y+ GQL C Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 L VE L + + +K+ V E + +C V VP + WL NG I+ + Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879 Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 + + +L I + ED YT + N QVS + VT Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921 Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674 PI + L D+ + +T V V+ WL NG EI+ ++ + Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973 Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 HSL I+ V D YT AG+ + A L V+ H F + + Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 + + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y + Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083 Query: 795 LLKNRV 800 + V Sbjct: 3084 VAGGNV 3089 Score = 78.2 bits (191), Expect = 7e-14 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%) Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 P T A + P + F + +V + + TG T TW K ++ + +K Sbjct: 7011 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7070 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 ++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI Sbjct: 7071 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7129 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404 S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V Sbjct: 7130 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7189 Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433 A N G EP+ E ++T P+ P++ Sbjct: 7190 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7221 Score = 78.2 bits (191), Expect = 7e-14 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA ++L V ++ +L + D + I L K + F + + + ++ Sbjct: 22174 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22233 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 E+ + + ++ AKNDAG +E P+ + V+ Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22265 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +K+ T + Q+I +AG + ++G TW + Sbjct: 22266 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22315 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337 ++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G Sbjct: 22316 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22375 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396 S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L Sbjct: 22376 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 EY FRV + N +G S+P + + + + E P P Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22468 Score = 77.4 bits (189), Expect = 1e-13 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%) Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072 Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509 G P+ + + G L + D+G Y+ N G+ S S +L +E Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567 + S +L V FV + V G P + + + ++ +A+ Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625 + ++ + + + E + ++ T E+ + + + + ++ S+ F Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247 Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683 + + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306 Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732 V PED G YT A N G L V+ P +I PRSV+ Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366 Query: 733 S 733 S Sbjct: 1367 S 1367 Score = 77.0 bits (188), Expect = 2e-13 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI Sbjct: 16858 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16917 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y N GQ S ++ D P + K P Sbjct: 16918 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16960 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 D + + PP QI + ++ T W Sbjct: 16961 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17004 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332 + + +KV + G++ + + EN+ G A + +V +P Sbjct: 17005 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17052 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385 PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT Sbjct: 17053 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17106 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 T F Q+L EY+FRV A N+ G + S+ SE + + P Sbjct: 17107 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17152 Score = 76.6 bits (187), Expect = 2e-13 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+ Sbjct: 6453 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6511 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206 +D Y C ++ +A + + V+ +AP ++ E+ + Sbjct: 6512 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6571 Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241 ++++ V G + + K + + A P+I Sbjct: 6572 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6631 Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301 +D V G+ + + W K + + ++ + + IL A+ Sbjct: 6632 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6688 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS Sbjct: 6689 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6747 Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418 + Y +E D KTW LAT R+ S F V L EY FRV A N GT EP + Sbjct: 6748 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6806 Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441 K + P + V+ D Sbjct: 6807 DNPVEARSKYDVPGPPLNVTITD 6829 Score = 76.3 bits (186), Expect = 3e-13 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%) Query: 1772 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1830 S TG+ E L E V++ E P P ++++ V+EG + +C Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918 Query: 1831 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977 Query: 1891 ATCTAELIVETMEEGEGE 1908 + + L V+ EE E E Sbjct: 978 VSTSCYLAVQVSEEFEKE 995 Score = 75.9 bits (185), Expect = 4e-13 Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678 K P+ L D +G V +T ++ EV W + E F Q + Sbjct: 4364 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4421 Query: 679 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737 +L I +V ED G Y CEA N +G+ T A LTV + P K + +LG Sbjct: 4422 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4478 Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797 +C I P W + G+ + ++ + ++ + +L + + Q G+Y Sbjct: 4479 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4537 Query: 798 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 N G SC +L + R L R+P E++ S+ Sbjct: 4538 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4584 Query: 854 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913 P + +E + E V K+ + + + EV + R+ +K+ T + Sbjct: 4585 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4637 Query: 914 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970 IP + + + +V KP V E + +P V V+ KK +K P E Sbjct: 4638 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4694 Query: 971 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027 P P + G KK P+ + + E P + + PLK V Sbjct: 4695 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4747 Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073 K + +G++ E L A K N++ + K D K+ Sbjct: 4748 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4807 Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124 + C + G+ T K + K ++V V +G+ L L C+++ + Sbjct: 4808 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4867 Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183 ++W +GK ++ I+ G + +++I A D G Y +N A ECS Sbjct: 4868 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4924 Query: 1184 QVTV 1187 V V Sbjct: 4925 CVKV 4928 Score = 75.9 bits (185), Expect = 4e-13 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%) Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105 N++P ++LK +E + D + + + +A G ++ + SE+ P + Sbjct: 7963 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8022 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165 D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D Sbjct: 8023 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8082 Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225 G+Y +N G A S V V P ++K+ SD T Sbjct: 8083 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8124 Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PP+ G PI ++ R++ ++ Sbjct: 8125 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8156 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343 V + EN T+ + + NK+G + N + P P P ++ Sbjct: 8157 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8216 Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395 + ++T++W YDGGS + Y IE + WK C ++ + L Sbjct: 8217 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8273 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442 EY+FRVRA N G SEPS+ + T + + PK +EV DE Sbjct: 8274 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8324 Score = 73.9 bits (180), Expect = 1e-12 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VKE Q V F CEV+ + WF + I + +D + L + A D Sbjct: 6279 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6336 Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 Y+ + +N +G+ + + L VE + V P LKD +E + C V V Sbjct: 6337 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6391 Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W NG+ + + H I+D D G Y VT Sbjct: 6392 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6435 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 + KS +E L+ AP++ F++ L D V + + Q+S V W NG Sbjct: 6436 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6487 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719 EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P + Sbjct: 6488 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6543 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 +P P+ + + G V+ + D V WLR+ + + H +++ + L Sbjct: 6544 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6596 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808 + ++P G+Y + K++ +++ Sbjct: 6597 QICDIKPRDQGEYRFIAKDKEARAKLELA 6625 Score = 73.9 bits (180), Expect = 1e-12 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V+V G L + +S P + + +G LK T ++++++++ D G Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224 Y+ A N +G + + V D P P V+ TE T+K Sbjct: 20174 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20219 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P PK + + I+ ++ S ++ +V+ T + T MK K E+ Sbjct: 20220 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20269 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344 +EN + + + S V L P PP+ TP +++ Sbjct: 20270 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20310 Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402 S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F Sbjct: 20311 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20370 Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 RV A N G +PS SE + E P++ V ++D + + ++ + K++ Sbjct: 20371 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20429 Query: 1463 FYDIEER 1469 Y +E R Sbjct: 20430 -YIVERR 20435 Score = 73.6 bits (179), Expect = 2e-12 Identities = 33/91 (36%), Positives = 56/91 (61%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++D +D Y CKA N LGE+TC AEL+V Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790 Score = 73.2 bits (178), Expect = 2e-12 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328 R+++ ++ +++ G+ L + ++ + + EN+ G S + T + Sbjct: 23895 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23954 Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386 + P+PP+ P D+ SS++LSW DGGS V Y IE +++ W + Sbjct: 23955 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24014 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437 T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+ Sbjct: 24015 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24067 Score = 72.4 bits (176), Expect = 4e-12 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%) Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++ Sbjct: 8726 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8781 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347 N S+L I A ++ G Y + N GS+ A + V D P P R Sbjct: 8782 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8841 Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407 L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A Sbjct: 8842 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8900 Query: 1408 NVYGTSEPSQESELTTV 1424 N +G P + + V Sbjct: 8901 NKFGCGPPVEIGPILAV 8917 Score = 71.6 bits (174), Expect = 7e-12 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%) Query: 1751 AVRAIGRLSSMAMIS--GLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK 1808 A A+G++SS A +S G S + +T + ++ +E + Q K Sbjct: 3372 ASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQ-------------K 3418 Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1867 P F + + L V G RF ++ G P PE+ WF + Q I ++ ++E G + Sbjct: 3419 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 3478 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +I D + +Y+CKA NS GEATC A L V Sbjct: 3479 LIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510 Score = 71.6 bits (174), Expect = 7e-12 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 +D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T Sbjct: 20792 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20850 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+ Sbjct: 20851 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20904 Score = 71.2 bits (173), Expect = 9e-12 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%) Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324 P T W++ K + +V+ N K + +L EN G + + Sbjct: 7552 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7600 Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 + + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W Sbjct: 7601 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7660 Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437 +A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV Sbjct: 7661 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7720 Score = 70.9 bits (172), Expect = 1e-11 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538 Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P + W +N I + ++ G +G +L I + +D YT A N +G Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597 Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161 ++ VE FA+ + + G +AP +E +G + P Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657 Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 F KL + +K F C++T G P V WL PL+ + R+ + + G L+ Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 D G+ TC N G SA L ++ +S V E++ Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759 Score = 70.9 bits (172), Expect = 1e-11 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 SE +GT P F +++ + ++ G L V P I W NG L + +G Sbjct: 3575 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3634 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 S+ I ED G Y C+A ND G+ CS + + N+K K Sbjct: 3635 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3680 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 TE+++ V K P PP ++ + + G V G T T Sbjct: 3681 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3732 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329 W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+ Sbjct: 3733 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3792 Query: 1330 KPDPPAGTPC 1339 + TPC Sbjct: 3793 EDTDMTDTPC 3802 Score = 70.9 bits (172), Expect = 1e-11 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21260 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y + N C++ V P + T P K + P Sbjct: 21261 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21291 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283 I+F E + +SV L V G ITC ++ R+ Q + Sbjct: 21292 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21333 Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337 M + + K+ L E+ + + EN+ G Q V+ +V K P PP G Sbjct: 21334 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21390 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395 P ++ S ++L+W YDGGS V + +E + + W+++ T + L+ Sbjct: 21391 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21450 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455 +Y+FRV A N G S PS S+ T+ P +P + D V T+T+ Sbjct: 21451 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21502 Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475 + D Y IE+R G+ ++ Sbjct: 21503 WNPPLRDGGSKIVGYSIEKRQGNERW 21528 Score = 70.5 bits (171), Expect = 2e-11 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A + I+ L+V +D F +P +++ + E A+FE + E Sbjct: 5092 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5140 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W + I S +F + + LVI+ +D G YT E Sbjct: 5141 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5185 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 VEG K R + KF + L VKEG+ F Sbjct: 5186 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5222 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C+++ + V W K + L S V +S + LE+ V DD+ V + Sbjct: 5223 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5277 Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283 S +A+L + D + + A D V K+V K+ Sbjct: 5278 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5337 Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337 K D L K K +G G+ AN + R K+E P + V Sbjct: 5338 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5392 Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397 + I L V + + G + + E Q G+ + +V + Sbjct: 5393 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5451 Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456 AAN + + P P S +V E KF CEVS PK W L+GT Sbjct: 5452 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5508 Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516 + E+ +D H + + A D Y A + +L + + F Sbjct: 5509 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5559 Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576 + LKD E + V + + R+ W N Q + RS + +QD Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5610 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 T+ L+ + Q+ A SE L V P F L D ++ Sbjct: 5611 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5659 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 +V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+ Sbjct: 5660 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5718 Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 G +T L +++ + + SV ++ I+ D +W Sbjct: 5719 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5769 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781 G+AL + T E+ + + +LVL Sbjct: 5770 KGEALLQ-TPDCEIKEEGKIHSLVL 5793 Score = 70.5 bits (171), Expect = 2e-11 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L + V G K+ L V+ P I WT LK K I + +V+I + Sbjct: 7325 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7384 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y A N G+A +V V D P PP +D T + Sbjct: 7385 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7426 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 PP+ +I + +++ E W K ++++ Sbjct: 7427 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7470 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339 K T L +E+ + + EN G Q + +T + DPP G P Sbjct: 7471 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7517 Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396 SDI ++TL+W DGGS + Y +E D W + T++ V+ L Sbjct: 7518 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7577 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 +Y+FRV A N+ G +PS+ +E + + + P Sbjct: 7578 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7612 Score = 70.1 bits (170), Expect = 2e-11 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1866 P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L I V + +Y+ KA N G+AT TAEL+V+ Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98 Score = 70.1 bits (170), Expect = 2e-11 Identities = 59/236 (25%), Positives = 92/236 (38%), Gaps = 24/236 (10%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA LQD +EG+ QC+VS + W K +K ++F ++Q + I Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD-APASENTKAPEMKSRRPKSSLPPVLGT 1216 +A PED G Y VA N GQ + ++++ + ENT + Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWH-------------V 3404 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 + KK+P P IQ +V GE+V +V+G W ++ Sbjct: 3405 SLSVSFKKEP-------LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQ 3457 Query: 1277 QIQESEHM--KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 I ++ + E S + + I+ A EH G Y+ N G LTV K Sbjct: 3458 LILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPK 3513 Score = 69.3 bits (168), Expect = 3e-11 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%) Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271 ESD V + P P TP A+ + + V G S + + + + W Sbjct: 17038 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17097 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 K K I K +N E G + + + EN +G +A N Sbjct: 17098 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17146 Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387 DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T Sbjct: 17147 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17206 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438 F V L D Y+FRV A N G S+PS + T ++ E P +D + V+ Sbjct: 17207 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17266 Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495 + E D + T + + +IEE F+ L+ K ++ G++ Sbjct: 17267 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17326 Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554 +A + ++ + +++ P+ VQ EK ++ + GG + E Sbjct: 17327 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17386 Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598 E + E + +++ EG EY+ + IM VNK G Sbjct: 17387 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17428 Score = 69.3 bits (168), Expect = 3e-11 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357 GC Y + EN G ++ DP P P D +++T++W + Sbjct: 19678 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19737 Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS Sbjct: 19738 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19797 Query: 1417 QESELTTVGEKPEEPKDEVE 1436 S+ E+ EEP +++ Sbjct: 19798 DSSDPQIAKEREEEPLFDID 19817 Score = 69.3 bits (168), Expect = 3e-11 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%) Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310 E S ++EVT + E + + + A + + S+ + R SP + Sbjct: 25857 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25916 Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368 S+PQP E + ++ + SP TP + PR+P SP Sbjct: 25917 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 25951 Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423 ER R A F +R + + K + R+ + Q+ P+ + +S Sbjct: 25952 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 26011 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 V Q +F V P EV W+ G ++ + I +G L +L T DSG Sbjct: 26012 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 26070 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542 TY +N +G+ S TL V G D+ S R V Sbjct: 26071 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 26108 Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596 PR + + YA S+ EA + ++ + E + + +A ++ +A Sbjct: 26109 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26168 Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654 ++ EK ++RK + L A L + V +G + G P P V Sbjct: 26169 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220 Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714 WL G + S + + I V D G Y+ NS G+ + LT+Q+ Sbjct: 26221 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26280 Score = 69.3 bits (168), Expect = 3e-11 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L AP L R+ + G +F V+ P +V W+ NG + + G Sbjct: 25998 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26056 Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121 +L I H +D G Y T + T G R V EL Sbjct: 26057 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26116 Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157 T ++A K+ + S ++ + + ETR S+ Sbjct: 26117 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26175 Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 + TK + V EG+ RFSC G P P VTWL+ L SAR Sbjct: 26176 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26235 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267 V+ EI V D G Y+ +V N GK L+IQ ++ V E KA Sbjct: 26236 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26288 Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327 S R V S E ++ S EA K SP+ P P + + E + Sbjct: 26289 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26339 Query: 328 SPRTAP 333 P +AP Sbjct: 26340 LPVSAP 26345 Score = 68.9 bits (167), Expect = 4e-11 Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%) Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502 EV W+ E V E + +D ++ L + K T D G Y C A N G+ + S L Sbjct: 4396 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4454 Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562 V V AP ++ V G C ++ P R W G+ I Y C Sbjct: 4455 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4509 Query: 563 AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618 ++ L I D G YTC A N G VSC+A +TV +K LLP Sbjct: 4510 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4569 Query: 619 KPTAPIFLQGL 629 +P + L+ + Sbjct: 4570 EPKEEVVLKSV 4580 Score = 68.9 bits (167), Expect = 4e-11 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%) Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 P KL V V G + L+ V P + WT + T+ + + Sbjct: 11829 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11888 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213 S+ KA D G Y A N AG V V D P N K ++ S R Sbjct: 11889 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11940 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 TV P P+ + I++ E +++ W Sbjct: 11941 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11973 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330 + + G+ +T L E+ + + ENK+G+ + V+ K Sbjct: 11974 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12021 Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 PDPP T + + +T+ W YDGG ++ Y +E + + W + + Sbjct: 12022 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12077 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 VQ+LLPDHEY+FRV+A N G EPS S V + P EP Sbjct: 12078 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12124 Score = 68.6 bits (166), Expect = 6e-11 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19082 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++A ED G Y+ N AG + V D P PP Sbjct: 19083 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19124 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 + + PP+ QI + ++K + + TW + Sbjct: 19125 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19168 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333 + + +K+ GS+ + + EN+ G + VV + P Sbjct: 19169 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19216 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386 P GTP S++ ++W DGGS V Y +E +W ANK Sbjct: 19217 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19271 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446 T V L Y++RV A N+ G + S+ E P +P + EV++ K Sbjct: 19272 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19330 Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475 + + + K++ + L G++ Sbjct: 19331 LKWSKPHYDGGAKITGYIVERRELPDGRW 19359 Score = 68.6 bits (166), Expect = 6e-11 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+ Sbjct: 26755 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26814 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194 ++ S+ I A D G Y AKN GQ + + V + P+ E Sbjct: 26815 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26874 Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235 ++++ +M + + ++S + + + + K A + + Sbjct: 26875 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26934 Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 +PP+I P D + G+ + + TG TW Sbjct: 26935 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26994 Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ + Sbjct: 26995 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048 Score = 67.4 bits (163), Expect = 1e-10 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%) Query: 1788 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198 Score = 67.4 bits (163), Expect = 1e-10 Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154 P Q+LQ V V GK +S P I W + L T KF+ QE +L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + +A PED +Y C AKND G A S ++V+ PE+ S P +P Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP II +D G+ +V+GT + +W Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 K+I+ S ++ E+ +L I A E G YT + N +G + NL++ Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387 Score = 67.0 bits (162), Expect = 2e-10 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 ++ + V G + + P T WT +G +KT + + + ++I+ L Sbjct: 11145 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11204 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y+ N AG + +TV D P P + + T T+ Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11252 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P P I E Q R + +G V+ Sbjct: 11253 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11283 Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336 +GS T L GC + + ENK+G + V K P P G Sbjct: 11284 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11336 Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390 P +DI ++ T+SW DGGS + Y +E W NKT F Sbjct: 11337 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11391 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 V L + Y+FRV A N+ G S+PS S+ Sbjct: 11392 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11421 Score = 67.0 bits (162), Expect = 2e-10 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224 A+N +G + ++ V D P + K +M S R S P L G+E + Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13054 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 K P A +V+ T PIT ++ K I+ E+ Sbjct: 13055 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13087 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340 + + ENK G + K DPP P Sbjct: 13088 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13124 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 S+I +T+SW + DGGS + Y +E ++ W ++ + L Sbjct: 13125 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13184 Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420 EY+FRV AIN G +PS S+ Sbjct: 13185 EYEFRVTAINKAGPGKPSDASK 13206 Score = 66.6 bits (161), Expect = 2e-10 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%) Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134 G +D S+ Q ++ L D+ K L+++ S P ++W+ Sbjct: 19792 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19851 Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 L+T ++ + S S++IE A D G Y +N A + V V D P Sbjct: 19852 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19907 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254 PP T D T + A + + PE+ Sbjct: 19908 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19932 Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312 G P+ ++ R + S+ V + N ++L+ + Y V Sbjct: 19933 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19981 Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E Sbjct: 19982 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20040 Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429 + K W + A +ST V L + EY FRV A N G S+P + + E+ E Sbjct: 20041 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20100 Query: 1430 EPKDEVE 1436 P+ +++ Sbjct: 20101 PPEIDMK 20107 Score = 65.9 bits (159), Expect = 4e-10 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8800 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y A N G + +V V D P P L PV+ T + Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8846 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P+ + + II+ +D K+ T QPI E+E K Sbjct: 8847 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8882 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342 + +T L QE+ + ++ +NK G ++ + VD PP ++ Sbjct: 8883 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8933 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400 S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y Sbjct: 8934 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8993 Query: 1401 KFRVRAINVYGTSEPS 1416 +FRV+A+N G SEPS Sbjct: 8994 EFRVKAVNEIGESEPS 9009 Score = 65.9 bits (159), Expect = 4e-10 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15163 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A N G A+ V V D P P V S+ V P Sbjct: 15164 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15210 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I+Q E ++ W ++Q ++ Sbjct: 15211 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15241 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346 K+T L E+ + ++ NK G + + V+ PDPP P + I Sbjct: 15242 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15297 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+ Sbjct: 15298 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15357 Query: 1405 RAINVYGTSEPSQES 1419 A N G S PS S Sbjct: 15358 MAENAAGISAPSPTS 15372 Score = 65.9 bits (159), Expect = 4e-10 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW + Sbjct: 15644 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15702 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q Sbjct: 15703 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15762 Query: 1418 ES 1419 S Sbjct: 15763 LS 15764 Score = 65.9 bits (159), Expect = 4e-10 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T Sbjct: 22970 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23028 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K Sbjct: 23029 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23082 Score = 65.5 bits (158), Expect = 5e-10 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89 +AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24613 Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149 L+I +V ++D Y ATN G+ T L VE L Sbjct: 24614 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24655 Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 PK +G V G++ +G+P P +TW KG + + V Sbjct: 24656 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24704 Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268 L +GV + D G Y N G + EL + + R Sbjct: 24705 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24758 Query: 269 SDVRKEVTNVISKESKLD 286 SDV ++ N+ E D Sbjct: 24759 SDVSRDSVNLTWTEPASD 24776 Score = 64.7 bits (156), Expect = 8e-10 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ K + G+ L ++ V P I W +G+ LK T + + + + + I Sbjct: 17940 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17999 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y A N AG A + V V + P PPV Sbjct: 18000 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18041 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D + PP QI + +++ T TW Sbjct: 18042 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18085 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331 + + +K+ + G++ + + EN+ G + V+ +P Sbjct: 18086 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18133 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389 PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F Sbjct: 18134 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18192 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 L EY+F+V A N+ G +PS+ SE + + P Sbjct: 18193 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18234 Score = 64.7 bits (156), Expect = 8e-10 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%) Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68 S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R Sbjct: 26166 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26224 Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126 GQ +++ R + + TF I +V D G Y+ N G ++ LT++ + Sbjct: 26225 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26282 Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157 K + P K+ R +P ET+P+ + Sbjct: 26283 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214 PPK L KE + + +C + +VTW K L+ + +G Sbjct: 26343 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26400 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 L+I+ + + D G Y C + G + + + Q S + + ++ SD + Sbjct: 26401 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26460 Query: 275 VTNVISK 281 + V K Sbjct: 26461 ESTVTRK 26467 Score = 64.3 bits (155), Expect = 1e-09 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G+++ + +V G TW K K + + + + +L I A + G Y Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11607 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +N G Q + V+D+P P +++ + T+SW +GGS + ++ + Sbjct: 11608 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11666 Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425 E K W +A+ + +LL ++EY FRV A N G P+ E++ + Sbjct: 11667 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11725 Query: 1426 -EKPEEPKD 1433 ++P EP++ Sbjct: 11726 IDRPGEPEN 11734 Score = 64.3 bits (155), Expect = 1e-09 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%) Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269 G +S+ V + P P PP PP I+ D SV L K TG PIT Sbjct: 13789 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13837 Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++F R + K K+T L E+ + ++ N G + + Sbjct: 13838 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13895 Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 V DP P G P +I +S+TL W YDGG + Y +E D +K+W + Sbjct: 13896 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13955 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431 +F V DL+ +Y+FR+RA N G S PS+ +E ++ E P Sbjct: 13956 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004 Score = 63.9 bits (154), Expect = 1e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y + EN+ G Q + V + P PP G D+ +S++LSW + Sbjct: 16726 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16784 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P Sbjct: 16785 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16842 Score = 63.5 bits (153), Expect = 2e-09 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%) Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271 S+ TV + P K P P + + +V+ E + G +V G + + W Sbjct: 15957 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16015 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +K K K E G + + + G +G V P Sbjct: 16016 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16066 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389 P G P A + +S+TL W +YDGGS + Y +E + W + + T F Sbjct: 16067 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16126 Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432 V L+ DH Y+FRV A N G SEPS+ + T ++ + P+ Sbjct: 16127 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16170 Score = 63.5 bits (153), Expect = 2e-09 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+ Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20574 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G A + +V + D P P + T T+ +P P Sbjct: 20575 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20621 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I++ E +V W SEH++ E Sbjct: 20622 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20651 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 T + E+ + + NK G + + +VV K P PP G P + I + Sbjct: 20652 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20708 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404 S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV Sbjct: 20709 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768 Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439 A+N G S+ SE + P P ++ ++D Sbjct: 20769 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20805 Score = 63.2 bits (152), Expect = 2e-09 Identities = 33/95 (34%), Positives = 48/95 (50%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+ Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 I DV +D A KA+N GE + A L+V+ + Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383 P P P D SS++L W + DGGS ++ Y +E+ + WK + T Sbjct: 9332 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9391 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D Sbjct: 9392 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9446 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383 + KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ + Sbjct: 10738 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10796 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432 C T + V L YKFRV A+N G S+P+ E V ++ E P+ Sbjct: 10797 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10845 Score = 63.2 bits (152), Expect = 2e-09 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%) Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063 K V +S PLS P L+ K + TL L P+ G AK D + S Sbjct: 12416 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12466 Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104 +EE D + + + + G + +K E++G A +Q L Sbjct: 12467 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12526 Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 + + + GKKL ++ V P T W + T+ + + + S + I Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12586 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215 + +D G Y A+N +G +V V DAP PP + Sbjct: 12587 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12631 Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 ++DA P + + I+ E V G+ V VT T + Sbjct: 12632 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12682 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 K I E++ +EN G L K+ AQ V +P Sbjct: 12683 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12727 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388 T D + ++W DGGS + Y IE +W AN T RST Sbjct: 12728 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12778 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 + L+ EY FR+ A+N G+S PS+ +E T P +P + EV D Sbjct: 12779 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12828 Score = 63.2 bits (152), Expect = 2e-09 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%) Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25266 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163 Y C+ N G EL V+G +++ +T+ + +T + E PP+F Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25320 Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220 L G+ RF IT P+P VTW K ++P + + G+ L I Sbjct: 25321 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25380 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + V DD YT + N G+ S A+L++ Sbjct: 25381 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410 Score = 62.8 bits (151), Expect = 3e-09 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%) Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143 D EK+ + P FK+KL + + +C+++ DP + W +GK L+ Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203 + + E CS+ A D G+ C A N G S + V D E + E + Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760 Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263 + L + E A T K P I+ +PE +V GE+ +VTG Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820 Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323 W + I++S+ +V + L I+ + G + EN G + +V Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879 Query: 1324 NLTVVDKPD 1332 L + + D Sbjct: 1880 KLEIQQRED 1888 Score = 62.8 bits (151), Expect = 3e-09 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386 KP PP P DI SS+ LSW YDGG +Q Y +E D + W Sbjct: 16465 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16523 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 T+ V+ LL HEY FR+ AIN G E + V EK E P ++++ Sbjct: 16524 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16574 Score = 62.4 bits (150), Expect = 4e-09 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14471 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277 + + N +GK S ++++ LD+ +R T T V +TN Sbjct: 14472 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14529 Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325 I ++ ++ A K C+ G S A N +P ++ Sbjct: 14530 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14589 Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385 ++P ++ T S+++L P+P+ G ++ E +R + T T Sbjct: 14590 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14644 Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425 GL Q + +A R P E + + P+ + + Q++ Sbjct: 14645 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14704 Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 K +K V G PKP V W +G + +Q + A S L + + DSG Sbjct: 14705 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14763 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522 Y TA N G++ T+QV + P F V D Sbjct: 14764 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14802 Score = 62.4 bits (150), Expect = 4e-09 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569 AP +KD G+ L C + G P+P I W G+ + +R + + L Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628 + ED G YTC+A N +G+V S S+ LL P P P+ + Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24266 Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688 + GS + + V G P P + W H +Q SE+ E L ++ V + Sbjct: 24267 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24322 Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 G Y + N G V A+L V+ +P + P + A L S +IS Sbjct: 24323 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24371 Score = 62.0 bits (149), Expect = 5e-09 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 I +D G +TC VN +G S S L++Q + F +ET A VT Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003 Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309 + E K ++S + + + Q G P A Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035 Score = 62.0 bits (149), Expect = 5e-09 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329 +++ + V + TI + H + ++ +NK G + + + Sbjct: 9884 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943 Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383 P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A Sbjct: 9944 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10002 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 S+ V L+ +Y+FRV AIN G S S+ T + P Sbjct: 10003 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10050 Score = 62.0 bits (149), Expect = 5e-09 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y AKN +G A+ S V V D P P +L T+ + T+ Sbjct: 11606 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11649 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 + P D G IT +++RK Q+ + Sbjct: 11650 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11680 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340 + L A E+ + + ENK+G ++ + + +D+P P A Sbjct: 11681 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11738 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 D + + L W YDGGS SY +E + W+ + + + T + V + + Sbjct: 11739 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11797 Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 Y+FRV+ N G S+ + E+ V E ++P ++++S Sbjct: 11798 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11836 Score = 61.6 bits (148), Expect = 7e-09 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143 T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++ Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194 +SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA + Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238 + E + R + + S ATV+ K P+ PPK + PP Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269 Query: 1239 QI 1240 I Sbjct: 270 SI 271 Score = 61.6 bits (148), Expect = 7e-09 Identities = 35/96 (36%), Positives = 46/96 (47%) Query: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 II D ++T A N G ++ + L VE +E Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505 Score = 61.6 bits (148), Expect = 7e-09 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%) Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364 + ++ EN G + + +D DPP G P +I ++TL W Y GG + Sbjct: 14959 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15017 Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421 SY +E D N W + F V L D Y+FRV A N G S PS+ S+ Sbjct: 15018 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15077 Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441 T + E PK +V+V D Sbjct: 15078 ITCRDDVEAPKIKVDVKFKD 15097 Score = 61.6 bits (148), Expect = 7e-09 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PAFK V G+ L + P + W + LK T + + ++I Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15835 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A ED G Y N AG+A + V V D P PP + Sbjct: 15836 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15877 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D T PP K G S+ + V T TW Sbjct: 15878 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15919 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331 S ++ TI A R + GC + + EN+ G S TV P Sbjct: 15920 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15966 Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387 P GTP + S+ + W DGGS V Y +E + + W +L T Sbjct: 15967 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16026 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F L EY+FRV A N+ G +PS+ SE V P +P E + Sbjct: 16027 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16085 Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475 ++ T + K++ + ++ L G++ Sbjct: 16086 QWKKPTYDGGSKITGYIVEKKELPEGRW 16113 Score = 61.6 bits (148), Expect = 7e-09 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P +K + VH E K+ + P TI W + L T + + S+S+ Sbjct: 16175 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16231 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A+ D G Y AKN AG+ + V V D P PE P V+ Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16274 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275 S T +K PP II + +++ E+ L V Q ++C Sbjct: 16275 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16324 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330 KV G++ T + ++ NK G + + VV K Sbjct: 16325 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16364 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388 PD P P + + S+ + W + DGGS + Y +E D W Sbjct: 16365 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16423 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 V L+ +H+Y+FRV A N G SEPS S Sbjct: 16424 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16454 Score = 61.6 bits (148), Expect = 7e-09 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W+K K + K + G + + + G +G V Sbjct: 18179 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18229 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388 P P G P A I +++TL W +YDGGS + Y +E D + W + T Sbjct: 18230 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18289 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 F V L+ D Y+FRV A N G SEPS S T ++ + P ++ Sbjct: 18290 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18338 Score = 61.6 bits (148), Expect = 7e-09 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%) Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W + Sbjct: 21773 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21828 Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435 + + R T F V L +EY+F V A N G S S L E P P V Sbjct: 21829 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21888 Query: 1436 EVSDDDEKEPEVDY 1449 +V+D + +++ Sbjct: 21889 KVTDTSKTTVSLEW 21902 Score = 61.2 bits (147), Expect = 9e-09 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC Sbjct: 18630 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18686 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 + F V L + EY FR+ AIN G EP+ E+ E P+ E++ Sbjct: 18687 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18738 Score = 61.2 bits (147), Expect = 9e-09 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 +HV G+ + L ++ PP W G L+ ++ + + + ++I + D G Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23435 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223 Y KN G + +V + D P P+ E DAT + Sbjct: 23436 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23480 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P+ A + +++ + + G + ++ +T + KF + + +E+ Sbjct: 23481 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23530 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 + + A + G Y +++++ ++ + + P PP T D+ Sbjct: 23531 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23571 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396 +TL+WY DGGS V Y +E W NK + RST L Sbjct: 23572 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23626 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432 EY+ RV AIN G+ +PS+ S+ + KP+ P+ Sbjct: 23627 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23668 Score = 60.5 bits (145), Expect = 2e-08 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T Sbjct: 13217 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13275 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 F V L+ D +Y+FRV A+N G S+PS Sbjct: 13276 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13304 Score = 60.5 bits (145), Expect = 2e-08 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 + ++P PP D SS L+W +DGGS + Y +E+ + W E Sbjct: 22168 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22226 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 + +F V+ L+ EY+FRV+A N G SEP + + E EP Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22273 Score = 60.5 bits (145), Expect = 2e-08 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P + + K + + C++ G P P++ W+ G + Q ++ D +H L Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24219 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 ++ D G Y+C A+N G++ S L ++ A + P + K + G L Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24276 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589 G PVP +TW + +Q + + T E H+ ++ + H G Y N Sbjct: 24277 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G V V + +K P KPT PI ++ L + + +S Sbjct: 24337 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24373 Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702 PP + W+ N E +E ++ + C E+ G Y A N+ G Sbjct: 24374 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24433 Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748 + +V+ ++ P + +P KP ++TA SC +A P Sbjct: 24434 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24475 Score = 60.5 bits (145), Expect = 2e-08 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G Sbjct: 26475 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26533 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 F L IH D G YTC N +G+ + +LT++ Sbjct: 26534 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26570 Score = 60.1 bits (144), Expect = 2e-08 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384 V KP PP G P D SS++++W YDGGS + Y +EI W+ + A Sbjct: 15381 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15439 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 ++TS+ + L + EYK R+ A+N G EP+ Sbjct: 15440 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15471 Score = 60.1 bits (144), Expect = 2e-08 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W K K + MKV + G Y + EN G + + V Sbjct: 19261 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19309 Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386 DP P G P ++I S++L W YDGG+ + Y +E + + W + + Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19369 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D Sbjct: 19370 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19425 Score = 59.7 bits (143), Expect = 3e-08 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 EK P F K + + ++ G A + G P P++ WF + + S ++ +D D Sbjct: 3576 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3635 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 + SLII +D+ +YTC A N G+ C+A L + + EG + E E Sbjct: 3636 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3684 Score = 58.9 bits (141), Expect = 5e-08 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 2/105 (1%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1861 +E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350 Query: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 D L I++ +D+ YT A N++G+ + TA L +E + E Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFE 3394 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%) Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464 ++ + DS + +P ++ E++ + EVS +L+ TPV + S V Sbjct: 4265 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4324 Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524 ++ L + + +S + S T A ++ + E + E P + L D Sbjct: 4325 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4378 Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580 EG L S+ T + W + + + + + L I EDH G Sbjct: 4379 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4436 Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 Y C A N G+ + SA +TV K AP+ + + L+V G Sbjct: 4437 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4479 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 T ++ P W G EI ES+ SL I D G YTC+A N Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4539 Query: 701 AGEVRTQAVLTVQEP 715 G V A LTV P Sbjct: 4540 YGSVSCTATLTVTVP 4554 Score = 58.9 bits (141), Expect = 5e-08 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%) Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189 W T+K TK + EGSL +++ A+N GQ++ + ++D Sbjct: 7758 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7801 Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249 + +++T + PP D T + PPK I ++ ++K Sbjct: 7802 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7852 Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 R G W+K K + +V + G+++ + G Sbjct: 7853 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7893 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 +G + ++ P P P +D + ++W +GGS + Y Sbjct: 7894 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7947 Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE Sbjct: 7948 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8007 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456 + +P ++E D E E V +R V + T Sbjct: 8008 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8045 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G+ L+ V P TI W K ++ + + + ++ A+ D G Y Sbjct: 17265 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17324 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 A N AG V V D P P V G S+ K Sbjct: 17325 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17367 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288 +PP I + +++ E+ L V ++ +T Sbjct: 17368 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17403 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343 N K+T L E+ + ++ NK G + + V+ K P PP ++I Sbjct: 17404 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17458 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401 S+T+ W DGGS + Y +E D + W + R T V L DHEY+ Sbjct: 17459 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17518 Query: 1402 FRVRAINVYGTSEPS 1416 FRV A N G EPS Sbjct: 17519 FRVSAENAAGVGEPS 17533 Score = 58.5 bits (140), Expect = 6e-08 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + +F C ++ + V W +G + + ++ D H L + ++ D G Sbjct: 5125 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5181 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ + +G+ + + RL V + F S L+D V EG+ C + + Sbjct: 5182 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5231 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604 + W N + +R+ + + H + + E L +S V E Sbjct: 5232 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5279 Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664 S+ + + L P F L D ++ ++T+ +VS + P V W +G EI Sbjct: 5280 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5330 Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724 S + + G + L I++ +D G Y C+ G +T+A +TV+ + + Sbjct: 5331 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5381 Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781 KP V +G++ ++ P VH W G+ L + E++++ L+L Sbjct: 5382 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5437 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827 Q G+ N + +V + S + + REP + Sbjct: 5438 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5497 Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884 L G + G DR+ ++ G + ++ ED + + +HT Sbjct: 5498 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5550 Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938 E IR + + L +D+ K+ V T LS D+++ + + N QR ++V Sbjct: 5551 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5602 Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997 S ++E K HS + F+ L+ TS+ V + + KL G Sbjct: 5603 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5645 Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055 + + + VE + + + S PV K + +KP NA Sbjct: 5646 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5692 Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112 +K+ K+ LKK +K+D+ GT + + + + L V V E Sbjct: 5693 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5749 Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + ++S D W L G+ L T + +EG + S+ + + G Sbjct: 5750 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5802 Score = 58.5 bits (140), Expect = 6e-08 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%) Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147 R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + + Sbjct: 18327 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18386 Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207 ++ ++ + D G Y N G V V D P P Sbjct: 18387 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18433 Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267 V G ++ P A + II+ E ++ Sbjct: 18434 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18475 Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 +W + ++Q + K+T L E+ + ++ NK G + + V Sbjct: 18476 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18521 Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381 KP P TP S I S+ ++W DGG+ ++ Y +E D W + Sbjct: 18522 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18581 Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 T V L H Y+FRV A N G EPS+ S Sbjct: 18582 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18619 Score = 58.5 bits (140), Expect = 6e-08 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T + Sbjct: 24159 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24217 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 L + +ED G YTC ATN G + + +L ++ + G P+ K G Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24268 Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210 G R GRP P +TW G LQ S +++ Sbjct: 24269 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24306 Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268 L + V + G Y + N G ++ IQ D V E N Sbjct: 24307 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24366 Query: 269 SDV 271 S V Sbjct: 24367 SAV 24369 Score = 58.5 bits (140), Expect = 6e-08 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386 +KP P G P + + S ++W + DGG+ +++Y +E + W + T R Sbjct: 24451 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24509 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE Sbjct: 24510 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24560 Score = 58.5 bits (140), Expect = 6e-08 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156 P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++ Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214 I LPED G Y+ A N AG C + V+ + K+ E R + + L Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25542 Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250 GTES +A V KPA T K +I + E++K+R Sbjct: 25543 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25597 Score = 57.8 bits (138), Expect = 1e-07 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1867 PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +IS DD +YT N GE + +A L+ E Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128 Score = 57.8 bits (138), Expect = 1e-07 Identities = 87/371 (23%), Positives = 148/371 (39%), Gaps = 50/371 (13%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 V KP PP D +S+TL+W YDGGS + Y +EI + + W+ + Sbjct: 17545 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17603 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSELR 17659 Query: 1445 PEVDYR---TVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVW----------A 1491 + R + I+ K +I G+F + +EK A Sbjct: 17660 KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDA 17718 Query: 1492 GKF-FKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI 1550 GK+ K ++ ++ + +++ P+ + + ++ A +V I+ GG + Sbjct: 17719 GKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNY 17778 Query: 1551 IDEDFELTERECIKYMRQISE---GVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFG 1607 + + E T + + S+ VE + + I + + EN V G ++ +D Sbjct: 17779 VIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV---GVPVETVDAV 17835 Query: 1608 LARRLE-----------NAGSLKVLFGTPEF-----VAPEVINYEPIGYATDMWSI---G 1648 A + S +++ PE V V+ +P G T+ WSI Sbjct: 17836 KAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG--TEKWSIVAES 17893 Query: 1649 VICYILVSGLS 1659 +C +V+GLS Sbjct: 17894 KVCNAVVTGLS 17904 Score = 57.8 bits (138), Expect = 1e-07 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%) Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V Sbjct: 17815 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17874 Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 Y +E+ + W +A + + V L EY+FRV+A N G S+P Sbjct: 17875 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17924 Score = 57.8 bits (138), Expect = 1e-07 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Query: 1790 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD Sbjct: 25401 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 Q + + +I ++ +L I D +D Y A N+ G +C A L VE + + Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520 Query: 1907 GEGEEEEE 1914 E + +EE Sbjct: 25521 QEFKSKEE 25528 Score = 57.4 bits (137), Expect = 1e-07 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1867 P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 ++ + +D A YTC+A N G AT +A L VE E Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286 Score = 57.4 bits (137), Expect = 1e-07 Identities = 96/428 (22%), Positives = 149/428 (34%), Gaps = 56/428 (13%) Query: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1149 + E G P+F Q L + V G+ + +VS P I W N + + TK ++ E Sbjct: 3411 KKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE 3470 Query: 1150 GS--LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV-DDAPAS------ENTKAPE 1200 S + + I A E G Y C A N AG+A C+ +TV AP S E E Sbjct: 3471 ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEME 3530 Query: 1201 MK----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFP 1244 MK + S + L S++ V P K P I+ Sbjct: 3531 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEV 3588 Query: 1245 EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEH 1304 + + G+ L V G W + S K + L IL + E Sbjct: 3589 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLED 3648 Query: 1305 CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY------- 1357 G YT + N G L + K + T S + S L + Sbjct: 3649 EGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKP 3708 Query: 1358 ----DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHE 1399 G A+ Y++ + TW K+L T S +F V D + Sbjct: 3709 IRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDS 3768 Query: 1400 YKFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455 + +A N+ G S + E E T + + P + K E +D + P ++ Sbjct: 3769 GLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALD 3828 Query: 1456 TEQKVSDF 1463 +EQ+++ F Sbjct: 3829 SEQEIATF 3836 Score = 57.4 bits (137), Expect = 1e-07 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358 QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D Sbjct: 18891 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18950 Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q Sbjct: 18951 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009 Score = 56.6 bits (135), Expect = 2e-07 Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%) Query: 921 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978 E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V + Sbjct: 4267 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325 Query: 979 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033 S+ ++K + + S + E K E+ L + GP+ P+ + E Sbjct: 4326 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4383 Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083 + NAK DE K + V + VN + H G Sbjct: 4384 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4442 Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138 T + K + + AP K+K++ + VA G C++ S P W G+ + Sbjct: 4443 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4502 Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198 + + + S+ I + D G Y C A N+ G C+ +TV P E Sbjct: 4503 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4561 Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 + R+P+ VL + ++K+P PK PK + PE + E V Sbjct: 4562 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4617 Query: 1256 EL 1257 E+ Sbjct: 4618 EV 4619 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10221 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 +AKN+AG+ + + V V D P T P + S Sbjct: 10222 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10261 Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 ++ F PED G PIT ++ +++ V Sbjct: 10262 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10295 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341 + T+ Q + + EN +G + +A V + P+ P Sbjct: 10296 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10354 Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399 ++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L Sbjct: 10355 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10414 Query: 1400 YKFRVRAINVYGTSEPS 1416 Y++RV A+N+ G +PS Sbjct: 10415 YEYRVSAVNIVGQGKPS 10431 Score = 56.6 bits (135), Expect = 2e-07 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + ++ V P T+ W + LK T+ + + ++I + + D G Y Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A+N G+ + V D P PP + D Sbjct: 14768 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14798 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 + + F D G V Q + TW++ + + + Sbjct: 14799 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14847 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 ++LT Q + + +N+ G + +V P PP GTP + + Sbjct: 14848 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14901 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV Sbjct: 14902 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14961 Query: 1405 RAINVYGTSEPSQESE 1420 A N+ G S+PS+ SE Sbjct: 14962 IAENMAGKSKPSKPSE 14977 Score = 56.6 bits (135), Expect = 2e-07 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%) Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115 E L ++ E + KND A ++ K + + TA Q + G Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22293 Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175 + +S P + W L LK T + ++ +++++ ++ D G Y +N Sbjct: 22294 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22353 Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235 AG S V V P P + V +++ V PK Sbjct: 22354 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400 Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 + I++ E T W ++ ++ K+ Sbjct: 22401 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22430 Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351 T L E+ + + EN+ G S+ + + + P P P + + ++++++ Sbjct: 22431 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22488 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N Sbjct: 22489 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22548 Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 G S+ S+ S + + P + EV+D Sbjct: 22549 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22577 Score = 56.2 bits (134), Expect = 3e-07 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387 P P P +D S +L+W YDGG + Y +E ++ W + T R T Sbjct: 14300 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14359 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+ Sbjct: 14360 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14410 Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469 RT+ + + F I+ R Sbjct: 14411 -RRTLVVRAGLSIRIFVPIKGR 14431 Score = 55.8 bits (133), Expect = 4e-07 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%) Query: 1777 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1834 P +++E E ++ A ++K KP + V+EG ARF C++ G Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820 Query: 1835 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878 Query: 1895 AELIVETMEE 1904 +L ++ E+ Sbjct: 1879 VKLEIQQRED 1888 Score = 55.8 bits (133), Expect = 4e-07 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 GC + ++ EN+ G + V + P PP DI S+++L+W +DG Sbjct: 14562 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14620 Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 GS + Y IE + W + T + V++L EY F+V A+N G S P +ES Sbjct: 14621 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14679 Query: 1420 ELTTVGEKPEEPK 1432 V E+ P+ Sbjct: 14680 RPVIVKEQTMLPE 14692 Score = 55.5 bits (132), Expect = 5e-07 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 AP F Q LQ V V EG + +S P + W +G+ + T+ + +S Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 ++I + G Y A N +GQA + ++ V A Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP +Q + VR G V L +VTG + + Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 +IQ S ++ + L I A E G Y++ N +G + L V + + P Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200 Query: 1335 A 1335 A Sbjct: 201 A 201 Score = 55.5 bits (132), Expect = 5e-07 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1863 P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G Sbjct: 24552 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24611 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 LII+ V DD Y +A N G + TA L VE Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648 Score = 55.5 bits (132), Expect = 5e-07 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F R + EG F C+I G P PE+ WFK++ I S + I + SL Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26820 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I + D KYT KA N G+ + TA L+V + E Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856 Score = 55.1 bits (131), Expect = 7e-07 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388 P PP P +D SS L W DGGS V Y +E + + W++ R T Sbjct: 10050 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10107 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D Sbjct: 10108 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10160 Score = 55.1 bits (131), Expect = 7e-07 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386 KP P P D + L W DGGS + Y +E W + R Sbjct: 11430 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11489 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 +F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D Sbjct: 11490 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544 Score = 55.1 bits (131), Expect = 7e-07 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268 TES + K K P PP++ + +++ E G +TG + + Sbjct: 12010 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12067 Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328 W+ K MKV+N +H + + EN++G + + V Sbjct: 12068 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12116 Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378 DP P G P D S+TL W YDGG+ + Y +E+ S ++ W Sbjct: 12117 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176 Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 K A F V L + EY+FRV A N G P++ E E E P+ ++ Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236 Query: 1436 EVS 1438 + S Sbjct: 12237 DAS 12239 Score = 55.1 bits (131), Expect = 7e-07 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399 D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L + Sbjct: 23273 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23332 Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424 Y FR+RA N G SEP + TV Sbjct: 23333 YLFRIRAQNEKGVSEPRETVTAVTV 23357 Score = 55.1 bits (131), Expect = 7e-07 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567 AP F L++ V + L C V G P P + W G+ I +Y + G + Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I +D Y A N G VS +A + V P+K P L+ Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24660 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP Sbjct: 24661 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24716 Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734 +D G Y A N G + V V +P G + +S+ + AS Sbjct: 24717 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24776 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760 G S + + + WLR G+A Sbjct: 24777 GGSKITNYIVEKCATTAERWLRVGQA 24802 Score = 54.7 bits (130), Expect = 9e-07 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383 PDPP I +++ LSW DGGS V Y +E WD + + W++ Sbjct: 9640 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9698 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431 F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9745 Score = 54.7 bits (130), Expect = 9e-07 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101 + G + K + G P P + W+++ + + + L C + T L + + DR Sbjct: 20513 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20568 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 G Y + N G+ T+ + + G P+ KT+ E +W Sbjct: 20569 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20620 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204 K+ +V++ + R + + +KGN + +P Sbjct: 20621 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20680 Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260 SV KN G+ + + + VV A +++S ++ D + + Sbjct: 20681 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20740 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320 + K T D R++VT + + + C+ G P +P Sbjct: 20741 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20786 Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378 K D P + + T SSITL ++ + G V GEE + Sbjct: 20787 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20846 Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421 T + PG+ VS A + P+E P+ Sbjct: 20847 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20906 Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478 S K + V+ G P P V W + + GS Y E+ S L + Sbjct: 20907 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 20962 Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528 TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G Sbjct: 20963 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 21021 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 ++ + + TW + + + D + + LAEN Sbjct: 21022 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 21072 Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637 +G E PV ++ API + D DG Sbjct: 21073 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 21118 Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697 V V E W H G I ++ + Q Q L + + G Sbjct: 21119 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21175 Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 + G + + ++ E P VT +G +V + G P P++ WL+D Sbjct: 21176 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21228 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817 G L K++ + E+ TL +K + H G+Y ++L N V C V + + Sbjct: 21229 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21285 Query: 818 ALPRG 822 + P+G Sbjct: 21286 SKPKG 21290 Score = 54.7 bits (130), Expect = 9e-07 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%) Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + + EN G S T+ P P GTP D+ ++TL W DGGS + Sbjct: 21457 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21516 Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419 YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S Sbjct: 21517 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572 Query: 1420 ELTTVGEKPEEP 1431 + ++ P Sbjct: 21573 GIIMTRDENVPP 21584 Score = 54.3 bits (129), Expect = 1e-06 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Query: 1797 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 +EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ + Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557 Query: 1857 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 I + G +L I D A YT A+N G T ++ VE +E E E E + Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613 Score = 54.3 bits (129), Expect = 1e-06 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447 G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W Sbjct: 5180 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5234 Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507 F + ++ + + +H L + + D +L Sbjct: 5235 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5284 Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565 V+E P F+ L D +E + L+C V VP + W +G+ I S G+ Sbjct: 5285 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5342 Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 L I+ A +D G Y C G A VTV + + KP Sbjct: 5343 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5384 Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684 L ++V G +++S P W G + S D + G +H L + Sbjct: 5385 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5439 Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744 TG + +A N+ ++ A L V+E FI+ V C + Sbjct: 5440 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5491 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782 + +P T WL+ + + D FE++++ ++V+K Sbjct: 5492 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5527 Score = 54.3 bits (129), Expect = 1e-06 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158 F+ KL + G+ L + S P + W + L+ + I + +L I Sbjct: 10452 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10507 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 KA D G Y V +N G + CQV V D P PPV Sbjct: 10508 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10549 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 D K P I +K G+ V + + + TC K K + Sbjct: 10550 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10605 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 + +++ ++EN Y + S +A+ V D PD P T Sbjct: 10606 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10650 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395 D S ++W +DGG + +Y +E ++ +K W + T F V DLL Sbjct: 10651 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10705 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448 +Y+FRV A N G +PS S+ + +P V D VD Sbjct: 10706 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10758 Score = 54.3 bits (129), Expect = 1e-06 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QL PV++K L PP F V G+ + GRP Sbjct: 15761 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15803 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242 P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A Sbjct: 15804 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857 Score = 54.3 bits (129), Expect = 1e-06 Identities = 26/77 (33%), Positives = 44/77 (57%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928 Query: 232 TCLVVNGSGKASMSAEL 248 V N G+ + S E+ Sbjct: 16929 GITVANVVGQKTASIEI 16945 Score = 54.3 bits (129), Expect = 1e-06 Identities = 25/72 (34%), Positives = 40/72 (55%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010 Query: 232 TCLVVNGSGKAS 243 T N +G A+ Sbjct: 18011 TVTATNSAGTAT 18022 Score = 54.3 bits (129), Expect = 1e-06 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1865 P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25376 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I+ V DDDA+YT A N GE +C A+L V Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410 Score = 53.9 bits (128), Expect = 1e-06 Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%) Query: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 +S + + A L V P +K + I LEV G A+F C+I+ P+ WFK Sbjct: 4444 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4499 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 + I ES I + + SL I D +YTCKA N G +CTA L V T+ GE Sbjct: 4500 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4557 Score = 53.9 bits (128), Expect = 1e-06 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16639 Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260 T + N SG + SA ++++ LD+ + Sbjct: 16640 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16697 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311 V + +AT VTN K+D L+ A P + P A Sbjct: 16698 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16757 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363 PQPP + ++ + + T S I +Q + R L Sbjct: 16758 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16816 Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411 + + GEE K + PR P + ++D+V + Sbjct: 16817 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16857 Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471 P + S V+ Q +K +SG PKP + W +G P+ +Q I V + Sbjct: 16858 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16914 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499 L + + D G Y T +N GQ + S Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTAS 16942 Score = 53.9 bits (128), Expect = 1e-06 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E A E KP ++D V S A+F K G P P +W KD ++I + +++ Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908 D+ G L I D YTC NS G + + +L ++ +++ E + Sbjct: 26529 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26578 Score = 53.1 bits (126), Expect = 2e-06 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R GRP P++TW + + +V + + L I +++D G Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17719 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289 Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D Sbjct: 17720 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17771 Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328 AK KN +R + AN + + S K+E+ + Sbjct: 17772 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17830 Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375 P + P L +TS+S+ + R G V + P G E K Sbjct: 17831 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17889 Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423 GL S KA N + +P+ + + P + + Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17949 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 ++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G Sbjct: 17950 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 18008 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 Y+ TA+N+ G + + ++ V V P F V D VI Sbjct: 18009 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 18052 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/82 (29%), Positives = 41/82 (50%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21655 Query: 230 VYTCLVVNGSGKASMSAELSIQ 251 VYT N SG A ++ +Q Sbjct: 21656 VYTVEAKNASGSAKAEIKVKVQ 21677 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + + Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +++ +D+ YTC A N +GE +++L+++ Sbjct: 24221 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24251 Score = 52.8 bits (125), Expect = 3e-06 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 PT + + V G V + + ++G PPP W G++++ESE E Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734 L I+E DTG YT E N G T V+ + +P T P I + S+T S Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23483 Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790 G + L + WL +++ + T F L + + + + G Sbjct: 23484 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23543 Query: 791 QYEILLKNRVGECSCQVSL 809 Y L++ V EC + + Sbjct: 23544 SY---LQSEVIECRSSIRI 23559 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90 AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127 LVI +D G+YT N G + L E + Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131 Score = 52.4 bits (124), Expect = 4e-06 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 1781 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1840 ++A+ + D Q + +A++ + P F V+ G + D G P P V Sbjct: 15749 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15807 Query: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV Sbjct: 15808 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865 Score = 52.4 bits (124), Expect = 4e-06 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%) Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280 K P TP PP+ P + SV L K G +T +++ ++ + Sbjct: 23943 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24002 Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332 H K + + +T L E+ + ++ +N +G S + + VV DKP Sbjct: 24003 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24060 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390 P S I S+TL W DGG + Y +E S + WK+ + F Sbjct: 24061 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24119 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438 + LL EY+FRV A N G S P S +++LT+ GE P K+ +V+ Sbjct: 24120 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24171 Score = 52.4 bits (124), Expect = 4e-06 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++ Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24615 Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 ++ + T D T Y A+N G +S + +L+VE A + + P + + G+ Sbjct: 24616 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24674 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587 ++ G P P ITW GQ + + V P +D G Y A+N Sbjct: 24675 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24733 Query: 588 ALG 590 G Sbjct: 24734 RFG 24736 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G Sbjct: 25206 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25265 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264 Y C VVN G+ S AEL ++G+ + R T Sbjct: 25266 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25300 Score = 52.0 bits (123), Expect = 6e-06 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%) Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164 ++ H+ G L L + P + W + T I ++ GS + I A ED Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10911 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 G+Y +N AG S +V V D P P+ + +S K Sbjct: 10912 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10959 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P G SV V + W ++ H Sbjct: 10960 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10997 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341 +E L +AA EN+ G + DP P G P Sbjct: 10998 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11045 Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399 D+ + ++L W DGGS + Y +E + + W + T + V L Sbjct: 11046 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11105 Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 Y+FRV+A N+ G P + EK P E++V Sbjct: 11106 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11142 Score = 52.0 bits (123), Expect = 6e-06 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21654 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145 G YT EA N SG+ + +++ V+ + K +G + G++ + Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698 Score = 51.6 bits (122), Expect = 7e-06 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%) Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469 ++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++ Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158 Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505 + L + +A DSGTYS A+N+ G+ + + L V+ Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 51.6 bits (122), Expect = 7e-06 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327 W K K + + H KV G + + EN G + Sbjct: 20344 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20392 Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +D +PP +DI +S++LSW ++DGGS + Y +E D + W + Sbjct: 20393 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20451 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417 T F + L + +Y+FRV A N G+ S PS+ Sbjct: 20452 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20484 Score = 51.2 bits (121), Expect = 9e-06 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385 + P PP P +D S+++ L W +++GG + Y ++ W + Sbjct: 8628 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8685 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + V+++ +YK RV A+N G P E++ TV E E P E++VS Sbjct: 8686 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8737 Score = 50.8 bits (120), Expect = 1e-05 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%) Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183 PP T+ W + K L + + S ++I + D G Y +N G+ + S Sbjct: 20927 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20986 Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238 V V D PA+ + SR + L PP++ S + ++K+ A K Sbjct: 20987 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21038 Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298 TW + + ++ SE Sbjct: 21039 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21064 Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356 + +L EN++G + V + PA S D +S+ LSW Sbjct: 21065 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21115 Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 +DGGS + Y +E +TW ++ V L +FRV A N G S+P Sbjct: 21116 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21175 Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439 + TV E P EV++SD Sbjct: 21176 TIGPI-TVKELIITP--EVDLSD 21195 Score = 50.8 bits (120), Expect = 1e-05 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%) Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343 SE K+T L E+ + ++ EN G A L +P P G P +D Sbjct: 21836 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21893 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401 ++++L W +DGG + Y IE+ + W ++ C T + V DL EYK Sbjct: 21894 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21953 Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 FRV AIN G + + + ++ P+ +++ + Sbjct: 21954 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21990 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777 G P + + VT LG++ +SC I G P P + W R GK L + + +++ + Sbjct: 24158 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24216 Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 TL + + G Y + N VGE L+LQ Sbjct: 24217 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251 Score = 49.7 bits (117), Expect = 3e-05 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%) Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 S P E + E P F L + VK G +TG+P+P++TW K ++ L+ Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7360 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252 R+++ + I + D G Y VN G+A+ E+++ Sbjct: 7361 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7420 Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 D N S + D ++TN + + DS Sbjct: 7421 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7455 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P PP G P S+ +SW +GGS + Y +E + + W ++ Sbjct: 9227 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9285 Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439 + FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D Sbjct: 9286 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9343 Score = 49.7 bits (117), Expect = 3e-05 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L V PP I W+ L+ + + + E D G Y Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13395 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G+ E + V V D P PPV T + + P Sbjct: 13396 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13437 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P II + ++ + K T C+ FR V N E Sbjct: 13438 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13480 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348 G + + EN+ G V P G +RS SS Sbjct: 13481 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13528 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408 ++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N Sbjct: 13529 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13587 Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 G P SE+T V +D+V D D K Sbjct: 13588 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13613 Score = 49.7 bits (117), Expect = 3e-05 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+ Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16924 Query: 789 AGQYEILLKNRVGECSCQVSLM 810 GQY I + N VG+ + + ++ Sbjct: 16925 GGQYGITVANVVGQKTASIEIV 16946 Score = 49.7 bits (117), Expect = 3e-05 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G Sbjct: 18745 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18802 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277 Y + N SG S +A ++++ LDS + +RE K + D ++TN Sbjct: 18803 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18860 Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330 I ++ + A + NC+ Q G S + + + E+ + Sbjct: 18861 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18920 Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383 + P P + T +T A ++ E + G V + K + T Sbjct: 18921 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18980 Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431 GL G + V AA R P E KP + VK + + Sbjct: 18981 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 19040 Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491 K G P+ V W +G + ++ + V L + +A D GTY SN Sbjct: 19041 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19099 Query: 492 AQGQLSCSWTLQV 504 + G ++ T+ V Sbjct: 19100 SAGSITVPITIIV 19112 Score = 49.3 bits (116), Expect = 4e-05 Identities = 24/81 (29%), Positives = 40/81 (49%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12992 Query: 230 VYTCLVVNGSGKASMSAELSI 250 YT N SG S + +L + Sbjct: 12993 DYTITAENSSGSKSATIKLKV 13013 Score = 48.9 bits (115), Expect = 5e-05 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%) Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190 W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100 Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250 P PP S+ + +K TPP I + +++ Sbjct: 14101 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14140 Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310 E+ L W + IQ H+ + + G++ + H G Sbjct: 14141 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14181 Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 G + +VD+ P P P S++ ++ T+SW DGGS + Y + Sbjct: 14182 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14236 Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426 E + + W + V L Y+FRV A N G PS+ S+ + + Sbjct: 14237 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14296 Query: 1427 K--PEEPKDEVEVSDDDEK 1443 P P V+D +K Sbjct: 14297 AAYPPGPPSNPHVTDTTKK 14315 Score = 48.5 bits (114), Expect = 6e-05 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%) Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62 I++T++++ P S P+T A +PPR L +K G + V G P P Sbjct: 12895 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12953 Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++ Sbjct: 12954 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13010 Query: 121 LTV 123 L V Sbjct: 13011 LKV 13013 Score = 48.5 bits (114), Expect = 6e-05 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%) Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 + +D PP P +D +S++L+W +GGS V Y IE+ W + Sbjct: 23652 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23709 Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 C +T +++ H EY+FRV A N G EP++ V E E P E++ Sbjct: 23710 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23767 Score = 48.1 bits (113), Expect = 8e-05 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566 + + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995 Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 LHI++ +D G YT A N+ G + + V V EK Sbjct: 17996 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18032 Score = 48.1 bits (113), Expect = 8e-05 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QLG PV+++ +E +PS+ E P F T VK + + GRP Sbjct: 19008 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19050 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ + Sbjct: 19051 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19108 Query: 249 SIQGLD 254 +I LD Sbjct: 19109 TIIVLD 19114 Score = 48.1 bits (113), Expect = 8e-05 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%) Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163 C TN ELT + + + V ++ D S P+ T P I + PP+ Sbjct: 19362 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19417 Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 + +VVK G++ + + I GRP P ++W K + ++ AR + + +L + Sbjct: 19418 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19477 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + D G Y + N +G S++ + Sbjct: 19478 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507 Score = 48.1 bits (113), Expect = 8e-05 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%) Query: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810 AV + + S M S + KS L++ + + ++ A LE + E+ Sbjct: 26123 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26182 Query: 1811 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 T+ R + V EG +ARF C +G P P V W + Q + S Q+ + Sbjct: 26183 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26241 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + IS V D+ Y+ NS G+ L ++ Sbjct: 26242 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279 Score = 47.8 bits (112), Expect = 1e-04 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1859 +++ KP+F K + L + A F+C++ DP +V W D + + + ++ Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708 Query: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +E G CSL D TC+A N G +A LIV+ Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749 Score = 47.8 bits (112), Expect = 1e-04 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%) Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322 G P+T ++ ++++ KV + + T+ Q + + NK G + Sbjct: 7143 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201 Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376 VN+ T PDPP D ++S+ L+W DGGS ++ Y +E + Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7260 Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 W T V L Y +RV+A+N G S+PS+ +E + E P+ + Sbjct: 7261 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7320 Query: 1436 EV 1437 +V Sbjct: 7321 DV 7322 Score = 47.8 bits (112), Expect = 1e-04 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%) Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478 K ++ + G P P+ +W +G + ++G ++ EDA S + + + + Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510 Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531 +G YS TA N GQ + + ++V + L V ++ + +G D Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9569 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 ++G + + T ++G+ C G + D L E + AEN G Sbjct: 9570 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9620 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 V ++ ++R P+ P P +K+ G TV +S PP Sbjct: 9621 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9663 Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 + W G + + + ++ + ++++ + +A Sbjct: 9664 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9722 Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756 N+AG + A + + P I + G +V I I G PFPT+ W + Sbjct: 9723 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9782 Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 D K H L +D TLV+ + + G Y I N +G S ++ L Sbjct: 9783 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9839 Score = 47.8 bits (112), Expect = 1e-04 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%) Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630 P D + +A NA+G +S S+ S ++ V P P + GL Sbjct: 21548 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21597 Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690 + G + + V G P P V W +G EI++ + SL +++ + Sbjct: 21598 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21654 Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714 G YT EA N++G + + + VQ+ Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQD 21678 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +++P PP +SD SS+ L W DGGS + Y IE + W + Sbjct: 6917 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6975 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 ++ V L ++Y +RV A N G S+PS+ T + EP ++ D Sbjct: 6976 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7030 Score = 47.4 bits (111), Expect = 1e-04 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632 +P++ T T L E A Q A V+ S S+ + +A + P + + S L Sbjct: 12874 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12933 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689 V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D Sbjct: 12934 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12990 Query: 690 TGTYTCEAWNSAG 702 +G YT A NS+G Sbjct: 12991 SGDYTITAENSSG 13003 Score = 47.4 bits (111), Expect = 1e-04 Identities = 25/82 (30%), Positives = 36/82 (43%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 + KE R I G+P P V+W KG PL RVSV L ++ + D G Sbjct: 13621 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13680 Query: 231 YTCLVVNGSGKASMSAELSIQG 252 YT + N +G + + + G Sbjct: 13681 YTITLKNVAGTKEGTISIKVVG 13702 Score = 47.4 bits (111), Expect = 1e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 L I +++D GKYT ATN +G + + V Sbjct: 17996 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 NA S S + E P + + + L + G + R ++G P P V Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21619 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+ Sbjct: 21620 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677 Score = 47.4 bits (111), Expect = 1e-04 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102 I+ G+ + V G PEP++ W + + + + L G R T VI D G Sbjct: 22687 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22744 Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158 KYT N SG + V+V + V S G+ VS+ ++ +S P + I Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22803 Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213 + T V+ EG+ S +T + +V + P P + +N Sbjct: 22804 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22863 Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269 + G+ ++ G ++ ++ E+S +D + +R T+ Sbjct: 22864 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22923 Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327 D R +VT+++ + C R + A NS+P S SC++ Sbjct: 22924 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22966 Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376 P +AP+ V+ T SI+L + + +G + E+ A Sbjct: 22967 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23024 Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420 R F +G + AA + ++G + + E +P Sbjct: 23025 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 23081 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479 ++ ++ +++ VSG P P + W +G + S + + S+ L ++ K Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23137 Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G Sbjct: 23138 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23193 Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590 G PV I + T + I + + L EN G Sbjct: 23194 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23247 Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 S V V E +P+ P+K L+V+D ++ T+T ++ Sbjct: 23248 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23283 Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705 P L++G + GT+ + + + P E T T E +R Sbjct: 23284 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23338 Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752 Q V EP + + R ++ G+ V + IAG P P Sbjct: 23339 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23398 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 W G L +++ V + V L +++ G+Y + LKN G S + +++ Sbjct: 23399 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23457 Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 + A ++ EP + GG G ++ + RPGW Sbjct: 23458 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23507 Score = 47.4 bits (111), Expect = 1e-04 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387 P PP G P + + W DGG+ + +Y ++ + + W + T Sbjct: 22868 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22926 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 V L+ +Y+FRV A+N G SEPS+ S + E P Sbjct: 22927 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22970 Score = 47.4 bits (111), Expect = 1e-04 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63 V + S S++ ++P +P E + + + I+ GA+ + V G P P Sbjct: 23048 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23105 Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 +TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V Sbjct: 23106 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23162 Score = 47.0 bits (110), Expect = 2e-04 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%) Query: 988 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045 ++++ + +GS E + VES +S + S V K + +A ++ Sbjct: 4266 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325 Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105 K + KP E + +S E ++V V + G + P L Sbjct: 4326 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4375 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164 D EG + L +++ + W K + + + Q+ + ++ I+K ED Sbjct: 4376 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4433 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 +G Y C A ND+G+ S ++TV K Sbjct: 4434 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4458 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 + AP K E +V G + ++ + W K ++I ES+ Sbjct: 4459 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4508 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 + +S+ S L IL + CG YT N+ GS LTV Sbjct: 4509 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551 Score = 47.0 bits (110), Expect = 2e-04 Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%) Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810 V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L Sbjct: 4397 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4455 Query: 811 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870 + +A + R EP ++ G + ++R W G+ + E D +R Sbjct: 4456 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4511 Query: 871 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917 +L+ +V + ++T +A + L G+K K L E K Sbjct: 4512 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4569 Query: 918 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963 P E++ ++ L++ + +PK ++ KV P ++V+ +V ++ Sbjct: 4570 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4627 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023 K P P KVP KPA P LPA E A+ P +P+ Sbjct: 4628 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4673 Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083 PV P K A E KP G P + + + ++ + + G Sbjct: 4674 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4728 Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137 + + + F ++++D+ + E G + +C VS P+T I W +G Sbjct: 4729 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4785 Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 ++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P Sbjct: 4786 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4839 Score = 47.0 bits (110), Expect = 2e-04 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%) Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169 EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+ Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25268 Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228 C ND G+ ++ V + + RR T+KK K Sbjct: 25269 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25308 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285 T PP+ ++ GE+V +T TW K ++I+ ++ K Sbjct: 25309 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25368 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334 E+ + +LTI + + YT++ NK G + LTV P P Sbjct: 25369 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25428 Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 G +IR S + TL W DG +IEI + Sbjct: 25429 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25479 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 + +++D LP+ +RV A N G++ ++ + K +E K + E +K+ Sbjct: 25480 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25536 Query: 1445 PEVDYRTVTI 1454 + R I Sbjct: 25537 IDKTLRMAEI 25546 Score = 46.2 bits (108), Expect = 3e-04 Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+ + + +G A FE V G P P VTW + + + + + + G+ + + Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144 ++ ED G Y C+A N G EL V P +K+ + Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3819 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PAVE S + AT + ++K + + +++ + L +PL Sbjct: 3820 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3874 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260 S+ E++ + + + C +NGS S L +Q + S ++F Sbjct: 3875 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3923 Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + ET+A SD K + +S E +++SL + P+ G P Sbjct: 3924 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3977 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353 S +PP S L S + +P+ + T+ +TLQ Q Sbjct: 3978 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4020 Score = 46.2 bits (108), Expect = 3e-04 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444 GLG D IP+E Q P E + E VK TV+F + G+P P Sbjct: 11117 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11169 Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504 W +G+ ++ E V D S L + RD+G Y T SNA G + + L V Sbjct: 11170 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228 Score = 46.2 bits (108), Expect = 3e-04 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 LP KE + + + ++G P P V+W + P+ + R ++ T +L+++ Sbjct: 13615 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13673 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125 + D GKYT N +G ++ T+ + V G Sbjct: 13674 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13702 Score = 46.2 bits (108), Expect = 3e-04 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%) Query: 1768 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1822 S ++ + P+ P E++ E V + A + +K SK I L VVE Sbjct: 26309 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26368 Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C Sbjct: 26369 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26419 Query: 1883 K 1883 + Sbjct: 26420 E 26420 Score = 45.8 bits (107), Expect = 4e-04 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I + Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188 D G YK + G+ E +C ++V+ Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485 Score = 45.8 bits (107), Expect = 4e-04 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864 PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I + Sbjct: 6000 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6055 Query: 1865 CSLIISDVCGDDDAKYTCK 1883 L+I+ DD+A+Y+C+ Sbjct: 6056 RILVINKCLLDDEAEYSCE 6074 Score = 45.8 bits (107), Expect = 4e-04 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565 ++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G Sbjct: 21585 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21641 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 L ++DA + G YT A+NA G V V + Sbjct: 21642 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21678 Score = 45.4 bits (106), Expect = 5e-04 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++ Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + L+I D KYT A G TA+L VE Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097 Score = 45.4 bits (106), Expect = 5e-04 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%) Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169 RQ TV+ EG+ K V + G P ET+P E A +L G Sbjct: 8687 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8741 Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + + G+ R +TGRP P W K L RV + L I + D G Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8800 Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 Y N G +A L ++ + + + + D E+T I Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8860 Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327 K++K+ + +E + + G + ++ + PP E D Sbjct: 8861 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8920 Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381 P T+P+ ++T S+ITL EPR+ G + E++R P Sbjct: 8921 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8976 Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423 PT + + D KA N +P+ Q D P + + + Sbjct: 8977 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 9036 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478 +VK + V +V+G+P P++ W T + + ++++ ++ S L + KA Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096 Query: 479 TRDSGTYSCTASNAQGQL 496 D GTY+ TASN G + Sbjct: 9097 REDKGTYTVTASNRLGSV 9114 Score = 45.4 bits (106), Expect = 5e-04 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%) Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567 +V P+FSS +V GQD ++ + G P P ITW +G P++ T + Sbjct: 16859 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16914 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I++ +D G Y N +GQ + S + +K P P P+ Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 16961 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651 +S ++ +S NPP Sbjct: 16962 DVS----------AESITLSWNPP 16975 Score = 45.4 bits (106), Expect = 5e-04 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 + G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010 Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715 T A NSAG +V+ +++P Sbjct: 18011 TVTATNSAGTATENLSVIVLEKP 18033 Score = 45.1 bits (105), Expect = 7e-04 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +K G + E V G P P + W ++G+ + + + T +LV D G Sbjct: 15101 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15159 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160 YT ATN G FAK + V G + V + + P Sbjct: 15160 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15206 Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215 P K+ +V++ + R + + QVT LK L+ + RV K G+ Sbjct: 15207 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15265 Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256 VL ++ D + C S S ++ D A Sbjct: 15266 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15325 Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315 + +++ K T +D+R +V+ + E + + A + SP +P Sbjct: 15326 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15385 Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366 PP + L++ + S A P+ S PE P A GL S Sbjct: 15386 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15444 Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423 + + + GLG +V KA +R +P E + D+ K + Sbjct: 15445 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15499 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481 ++ T++ + G P PEV W + E + ++ S Y L+ D Sbjct: 15500 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15553 Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 SG Y T N+ G S ++V + L V EV + ++ D +++G + Sbjct: 15554 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15613 Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593 V R + + C ++ D L E Y LAEN G + Sbjct: 15614 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15662 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 A K S R P+ P K T +MD ++ +V +S P Sbjct: 15663 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15701 Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 H+G + +G+ + + C E T T + + V Q + Sbjct: 15702 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15757 Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 +P + P I+K + T G+ + + G P P V W +D L Sbjct: 15758 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15816 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802 K T E+ L +K G Y + L N GE Sbjct: 15817 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15856 Score = 45.1 bits (105), Expect = 7e-04 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%) Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284 P PP A P++ + +R E G I W+ K R I + Sbjct: 22465 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22519 Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 KV E K+T L E+ Y L + +A + + D P G P +D+ Sbjct: 22520 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22578 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398 S+++L W +YDGGS V Y IE + + + W + F V L Sbjct: 22579 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22638 Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 Y+FRV A N G S+ S+ + T ++ PK E++ Sbjct: 22639 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22677 Score = 44.7 bits (104), Expect = 9e-04 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%) Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 W+ +G+ I+ES F G L I +V D G YTC E + A L V+E Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838 Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775 + + VT GQ + +SC + + V W +DGK + + G Sbjct: 4839 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4893 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810 + L + AG Y + ++N ECS V ++ Sbjct: 4894 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4929 Score = 44.7 bits (104), Expect = 9e-04 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386 P P G P D+ S+++L W +DGGS + Y +E W T Sbjct: 12817 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12876 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + L +Y+FR A S PS+ S+ T+ + P+ ++ V+ Sbjct: 12877 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12928 Score = 44.3 bits (103), Expect = 0.001 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99 L +K G T +F +RG P P W +G I + + ++ FS L I Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11204 Query: 100 DRGKYTCEATNGSGARQVTVELTV 123 D G+Y +N +G++ V V LTV Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTV 11228 Score = 44.3 bits (103), Expect = 0.001 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%) Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 +EK S + +PV A P F + V+ G + + V G P P V W + Sbjct: 15753 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15812 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718 ++++ + E L I++ ED G Y + NSAGE + T V+ + +P Sbjct: 15813 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15872 Query: 719 TQP 721 T P Sbjct: 15873 TGP 15875 Score = 43.9 bits (102), Expect = 0.002 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V+V+ G R + GRP P+VTW K + + V + M L I +DD G Sbjct: 12244 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12302 Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279 Y+ +VN +G+ ++ + + + S V +T +D +VT+ I Sbjct: 12303 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12362 Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311 ++ + D A P P A++ Sbjct: 12363 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12422 Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365 S+P PPR+ ++ + T P L+ K IT QP R V+ Sbjct: 12423 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12482 Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413 G++ K R A + P G V +A + +P Sbjct: 12483 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12527 Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 PK P+ +K + ++ V G P P W +G + V++ S L Sbjct: 12528 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12585 Query: 474 LLKARTRDSGTYSCTASNAQG 494 + +DSG YS TA N+ G Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606 Score = 43.9 bits (102), Expect = 0.002 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L Sbjct: 12527 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12585 Query: 220 IHGVNQDDVGVYTCLVVNGSG 240 I V + D G Y+ N SG Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%) Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 VK V ++ +SK S +V P R D P + F+ ++EG +++G P Sbjct: 9719 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9772 Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 P +TW + N +P+ T + ++D T +LVI D G YT A N Sbjct: 9773 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9828 Query: 111 GSGARQVTVELTVEG 125 G + L V G Sbjct: 9829 NLGTASKEMRLNVLG 9843 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 1810 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 + +KT++++EV E A F+C++ + P +W K+ I S F+I + LII Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 + +D A+YT N AT T I+ T + EE++ Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938 Score = 43.1 bits (100), Expect = 0.003 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1870 +EV EG+ KI+G P P + WFK +++ + YD D C+L+I Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9812 Query: 1871 DVCGDDDAKYTCKAVNSLGEAT 1892 D YT AVN+LG A+ Sbjct: 9813 QSRRSDTGLYTITAVNNLGTAS 9834 Score = 43.1 bits (100), Expect = 0.003 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 Y N SG A SA +++ LD + K TN V KE IS E+ LD+ Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11656 Score = 43.1 bits (100), Expect = 0.003 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V E K + P + + G R + + G P P W K + + S H + Sbjct: 12516 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12575 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + D + LII DV D Y+ A NS G T +++V Sbjct: 12576 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616 Score = 43.1 bits (100), Expect = 0.003 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1838 NA + SE S + A E P + P + TI V G + + D I G P P Sbjct: 16145 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16201 Query: 1839 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 + W K DQ + + +I D SL + D D Y KA N GE + T + Sbjct: 16202 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16260 Query: 1899 V 1899 V Sbjct: 16261 V 16261 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390 P PP S + S+TL W DGGS + Y IE + + W + Sbjct: 19611 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19669 Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421 V+ L EY++RV A N G S PS+ S L Sbjct: 19670 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19702 Score = 42.7 bits (99), Expect = 0.003 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%) Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150 +G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 +++++ ED+G Y V Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 + G ++ +K KP P I+Q DQKV G+ V+L KV+ + + Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401 Query: 1331 PDP 1333 P Sbjct: 2402 ITP 2404 Score = 42.7 bits (99), Expect = 0.003 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Query: 1811 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1864 F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D Sbjct: 4745 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +I DV D +YTC E T TA+L+VE + Sbjct: 4803 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838 Score = 42.7 bits (99), Expect = 0.003 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%) Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167 + + TV G Q + V++K S P+ T P + PKF Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17262 Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227 +VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D Sbjct: 17263 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17320 Query: 228 VGVYTCLVVNGSGKASMSAELSI 250 G Y N +G S + + Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKV 17343 Score = 42.4 bits (98), Expect = 0.004 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%) Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107 +KS K +++ K + + +N + H G + + T+ A F++ ++D+ Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021 Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167 V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080 Query: 1168 YKCVAKNDAGQAE 1180 Y VA + A+ Sbjct: 3081 YTVVAGGNVSTAK 3093 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 +K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10915 Query: 232 TCLVVNGSGKASMSAELSI 250 + V N +G ++S ++ + Sbjct: 10916 SLTVENPAGSKTVSVKVLV 10934 Score = 42.4 bits (98), Expect = 0.004 Identities = 21/72 (29%), Positives = 34/72 (47%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++++ G R + GRP P++TW K NV L+ + + + L VN+ D G Sbjct: 13331 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13390 Query: 230 VYTCLVVNGSGK 241 Y + N GK Sbjct: 13391 KYILTLENSCGK 13402 Score = 42.4 bits (98), Expect = 0.004 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + + V G P P V W +++++ +FE T L I E D+G Y Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767 Query: 697 AWNSAGEVRTQAVLTVQ 713 A N GEV V+T+Q Sbjct: 14768 ARNIVGEVGD--VITIQ 14782 Score = 42.4 bits (98), Expect = 0.004 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576 KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+ Sbjct: 16178 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16237 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633 D G Y A+N G+ S VTV+ K R P P P+ + G++ K Sbjct: 16238 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16284 Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656 + DG + V ++W Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVW 16312 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 +P VKP FS V G + + I G P P + W KD ++++ + D Sbjct: 16857 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16911 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 +L I + DD +Y N +G+ T + E++ Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16946 Score = 42.4 bits (98), Expect = 0.004 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795 + + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+ Sbjct: 19038 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19096 Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 + N G + +++++ + P + SC+ + Sbjct: 19097 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19132 Score = 42.0 bits (97), Expect = 0.006 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158 F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I Sbjct: 5915 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5972 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 PED Y C DA + SC + V Sbjct: 5973 DCTPEDIKTYTC----DAKDFKTSCNLNV 5997 Score = 42.0 bits (97), Expect = 0.006 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E F N+ + E T K V P +V W++ + I GR+ + R Sbjct: 6087 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6145 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 LVI H ED G Y C + +V V Sbjct: 6146 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6176 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 E +F +K + + EG+ F C I+ P V W + + L+ + Sbjct: 6177 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6226 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 V +VL + D+G Y +V G A +A L++ Sbjct: 6227 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6264 Score = 42.0 bits (97), Expect = 0.006 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578 G+ + V G P+P+I W N I+ + EL I A+ ED Sbjct: 9041 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9100 Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605 GTYT A N LG V + V V+++ S Sbjct: 9101 GTYTVTASNRLGSVFRNVHVEVYDRPS 9127 Score = 42.0 bits (97), Expect = 0.006 Identities = 26/93 (27%), Positives = 39/93 (41%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P+ + ++ + L V G+ V + G P P W +G+EI+ E + E Sbjct: 11136 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11195 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 L I+ DTG Y N+AG LTV Sbjct: 11196 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228 Score = 42.0 bits (97), Expect = 0.006 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V G P P+V W G ++G +++ + +L + + DSG YS T N G+ Sbjct: 12258 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12315 Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 + ++V L V +V + V +G V V R TW Sbjct: 12316 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12373 Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609 + T E H+ + +P + + A N G V K S Sbjct: 12374 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12421 Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666 + L S+P P + ++ +++T PP L +G + Sbjct: 12422 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12463 Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716 E+ R T++S+ ++++ TG + A N+ G + V E Sbjct: 12464 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12522 Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776 + P I P +T G+ + I + G P PT W + G+ + H V + + Sbjct: 12523 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12581 Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820 L++K V +G Y + +N G + ++ +++ ++ P Sbjct: 12582 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12625 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T G +V + + G P PTV W +DG L K ++ ++ TL L V + Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12991 Query: 790 GQYEILLKNRVGECSCQVSL 809 G Y I +N G S + L Sbjct: 12992 GDYTITAENSSGSKSATIKL 13011 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 VV+ G R GRP P W K + L S R + + L + N++D G Sbjct: 21996 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22053 Query: 231 YTCLVVNGSGKASMSAELSI 250 YT V N SG S++ + + Sbjct: 22054 YTLTVENNSGSKSITFTVKV 22073 Score = 42.0 bits (97), Expect = 0.006 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639 + LA+NA G +S + T + + EY AP K L G DL + GS Sbjct: 22642 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22692 Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699 + + V G P P++IW E+ E + G + + I+ D+G YT N Sbjct: 22693 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22752 Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721 ++G T+AV + + D P Sbjct: 22753 ASG---TKAVSVMVKVLDSPGP 22771 Score = 42.0 bits (97), Expect = 0.006 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 T D ++ P E + G+ V ++ G + G+P+P++ W KG+ Sbjct: 22664 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22713 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255 L +VS+ I ++ D G YT V N SG ++S + + LDS Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22768 Score = 41.6 bits (96), Expect = 0.008 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98 +N+ + E TA FE V + P + W +NG I +F + ++G L+I Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899 Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134 ED +YT N + +TV E+TV EG K L Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959 Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168 V K+ GD F A + +++ E +F + Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019 Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 + V E + F C+++ P V W+K + LQ + R+ + ++ + L I D Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078 Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 G YT + +G +A+L ++G D RS +E + Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111 Score = 41.6 bits (96), Expect = 0.008 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V + Q + CE++ + +V W +G V + G I L + A D+GT Sbjct: 4852 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4909 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ T NA L CS ++V V + ++D V + C + P Sbjct: 4910 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 4963 Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 I W + +P + L I++A+PED Y E A +T Sbjct: 4964 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 5019 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 + E R+ E L P+ D+ + + + ++S P W Sbjct: 5020 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 5060 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 G ++ S + G + L + +V + G +A N+ T A+LTV+E Sbjct: 5061 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 5112 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 + F + VT + C + + V W + G + K + F+++ + L Sbjct: 5113 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5169 Query: 780 VLKKVQPWHAGQY 792 V+ Q G Y Sbjct: 5170 VINDSQFDDEGVY 5182 Score = 41.6 bits (96), Expect = 0.008 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6150 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1913 + +D Y C+ +S + EL E + + + EGE+ E Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198 Score = 41.6 bits (96), Expect = 0.008 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%) Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64 A+ ISK S S P + + E P + P+ + + G T + E V G P P + Sbjct: 17228 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17285 Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 W R + I R C I+ T L++ D G+Y A+N +G++ V + Sbjct: 17286 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17341 Query: 122 TV 123 V Sbjct: 17342 KV 17343 Score = 41.6 bits (96), Expect = 0.008 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++VK G + GRP P V W K + L+ A V ++ L I N++D G Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19881 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 YT + N AS++ L ++ LD+ T T DV KE Sbjct: 19882 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19920 Score = 41.6 bits (96), Expect = 0.008 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21656 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 Y+ A NA G ++V+ V P Sbjct: 21657 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21686 Score = 41.6 bits (96), Expect = 0.008 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1864 + P D+ + EG C G P PEV W + I +E F I+ + D Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27013 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +LII DV D YT N G + T + + ++ Sbjct: 27014 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051 Score = 41.2 bits (95), Expect = 0.010 Identities = 24/96 (25%), Positives = 43/96 (44%) Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217 +C P + ++V EG+ P P V+W K ++ S R+++ + Sbjct: 8012 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8071 Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253 LE+ + D G+YT + N G A+ S + + GL Sbjct: 8072 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8107 Score = 41.2 bits (95), Expect = 0.010 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570 P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L + Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8074 Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600 ++ D G YT EN LG + S V V Sbjct: 8075 PKSVRADAGIYTITLENKLGSATASINVKV 8104 Score = 41.2 bits (95), Expect = 0.010 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454 VSK + P + QR P + K + EV+E V ++ G+P P + WF P Sbjct: 9727 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9783 Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506 ++ + V D + L C L ++R D+G Y+ TA N G S L V Sbjct: 9784 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9843 Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557 V P F SV D + +G + + R TW+ ++ +P Sbjct: 9844 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9899 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 C + +L L + +A+N G + + + ++ + +P AP Sbjct: 9900 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 9948 Query: 618 SKPT 621 KPT Sbjct: 9949 DKPT 9952 Score = 41.2 bits (95), Expect = 0.010 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K I L V G+ RF I G P P W D I+ H+ ++ D + L I + Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11201 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D +Y N+ G T L V Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTV 11228 Score = 41.2 bits (95), Expect = 0.010 Identities = 23/80 (28%), Positives = 36/80 (45%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G++ ++ I G P P V W +DGK L + E+ TLV+K Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404 Query: 790 GQYEILLKNRVGECSCQVSL 809 GQY + L N G S +++ Sbjct: 18405 GQYILKLSNVGGTKSIPITV 18424 Score = 41.2 bits (95), Expect = 0.010 Identities = 26/85 (30%), Positives = 34/85 (40%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L+L V P IIWT K L + + L G + I+ D G Sbjct: 22685 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22744 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y KN +G S V V D+P Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDSP 22769 Score = 40.8 bits (94), Expect = 0.013 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 +++ + E + ++ I + DTGTY EA N G R AV+ V Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7406 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D Sbjct: 7323 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7381 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y +AVN G AT E+ V Sbjct: 7382 KRSDTGTYIIEAVNVCGRATAVVEVNV 7408 Score = 40.8 bits (94), Expect = 0.013 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389 P PP + I ++ L W DGGS + +Y +E D K W+ + T + T Sbjct: 7712 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7770 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414 V L Y FRV A N G S+ Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSD 7795 Score = 40.8 bits (94), Expect = 0.013 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P IL P + IK G + E V G P P W + + + + + L+ Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12585 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I V +D G Y+ A N SG +++ V Sbjct: 12586 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616 Score = 40.8 bits (94), Expect = 0.013 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%) Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542 ++ +A N +G +S L V +A + + P+F + V+ G+D + G P Sbjct: 15746 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15804 Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V Sbjct: 15805 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15864 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624 V +K P PT P+ Sbjct: 15865 VLDK-------------PGPPTGPV 15876 Score = 40.8 bits (94), Expect = 0.013 Identities = 20/81 (24%), Positives = 39/81 (48%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G Sbjct: 16181 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16240 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y N +G+ S++ + + Sbjct: 16241 NYILKAKNVAGERSVTVNVKV 16261 Score = 40.8 bits (94), Expect = 0.013 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 ++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+ Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16927 Query: 104 YTCEATNGSGARQVTVEL 121 Y N G + ++E+ Sbjct: 16928 YGITVANVVGQKTASIEI 16945 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 ++P + G + + + G P P + W KD + ++++ ++ + + Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17996 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + DD KYT A NS G AT +IV Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/74 (31%), Positives = 33/74 (44%) Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 Q+ + V G P V W +G ++E+ + T SL I+E ED GTY Sbjct: 19039 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19098 Query: 699 NSAGEVRTQAVLTV 712 NSAG + + V Sbjct: 19099 NSAGSITVPITIIV 19112 Score = 40.8 bits (94), Expect = 0.013 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757 +V EP + T P + PR + G+ + I+ IAG P P + W +D Sbjct: 19395 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19454 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808 G + ++ E++ ++ L +K GQY + LKN G S V+ Sbjct: 19455 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19504 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5972 Query: 1871 DVCGDDDAKYTCKA 1884 D +D YTC A Sbjct: 5973 DCTPEDIKTYTCDA 5986 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + ++ G T + RV+G PEP +TW + G+ + R L + L I D Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11604 Query: 102 GKYTCEATNGSGARQ 116 GKY A N SG Q Sbjct: 11605 GKYIISAKNSSGHAQ 11619 Score = 40.4 bits (93), Expect = 0.017 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11606 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y +A N+ G S + V + L V V ++ + + G + V Sbjct: 11607 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11666 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596 +P Q S + V + I+ + L + + AEN +G Sbjct: 11667 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11710 Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650 T+ K +L + P +P P +L + D + + ++ G Sbjct: 11711 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11758 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705 P + H ++ S+D+ +G+ + + + + N GE V+ Sbjct: 11759 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11816 Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763 T+ V+ + D +P K V T G ++ + + G PFP V W +D A Sbjct: 11817 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11873 Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 + ++ D L K + G+Y + N G Sbjct: 11874 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11911 Score = 40.4 bits (93), Expect = 0.017 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VK V V G P P V+W +GT ++ EG I++ L L +DSG Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 12993 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y+ TA N+ G S + L+V Sbjct: 12994 YTITAENSSGSKSATIKLKV 13013 Score = 40.4 bits (93), Expect = 0.017 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%) Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL Sbjct: 17236 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17289 Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605 + I+ + + CE A L ++DA+ D G Y A N G S V V ++ Sbjct: 17290 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17346 Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633 P P P+ + G++ K Sbjct: 17347 -----------PGPPEGPVQVTGVTSEK 17363 Score = 40.0 bits (92), Expect = 0.022 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%) Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72 DP+ V L E P IL R IK G T + ++G P P+VTW + + Sbjct: 10827 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10886 Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + R +D G+ + +A H ED G Y+ N +G++ V+V++ V Sbjct: 10887 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10934 Score = 40.0 bits (92), Expect = 0.022 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482 VK T++ V G P PEVAW + T + R +++ A S L KA+ D Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11899 Query: 483 GTYSCTASNAQGQLSCSWTLQV 504 G Y TA+N G T+ V Sbjct: 11900 GKYVVTATNTAGSFVAYATVNV 11921 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%) Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656 V V+EK S +P VA P S V G + + V +SG P P + W Sbjct: 16832 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16891 Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715 +G ++++ + +L I+E +D G Y N G+ + ++T+ +P Sbjct: 16892 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16951 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575 KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D + Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y N G S V V ++ P P P+ + G++ Sbjct: 18402 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18443 Score = 40.0 bits (92), Expect = 0.022 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%) Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 Q+ V+ +++ G P P W P +++ L + Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 22049 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y+ T N G S ++T++V + +V ++++ D +++G + Sbjct: 22050 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 22109 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 V R +W Q C + +++ LAE Sbjct: 22110 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22149 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 SA V+E E P+ ++ AP L V+D S+ + + Sbjct: 22150 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22193 Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700 WL H+G Q+ DF E T Q + ++ + + + +A N Sbjct: 22194 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22251 Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 AG + + ++EP + T + +T G I I+G P P V W Sbjct: 22252 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22311 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 + L K+T + +D TL +K +G+Y + L+N G + V++++ Sbjct: 22312 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22370 Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844 P S E + G DGGG++ Sbjct: 22371 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103 G AKF ++ P + W + G+ I + C IR + SL I D G+ Sbjct: 4476 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4531 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 YTC+A+N G+ T LTV G+ V K L +R P E Sbjct: 4532 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4574 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Query: 1788 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V Sbjct: 5619 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5677 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 WFKD + I+ S++ I D LI+ D +YTC Sbjct: 5678 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5717 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73 PSR + ++ EAP L + L +K G + V G PEP++TW + + Sbjct: 7300 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7359 Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 R ++ + ++ I D G Y EA N G VE+ V Sbjct: 7360 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408 Score = 39.7 bits (91), Expect = 0.029 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + + +P P V+W +G V+ + + + D S +L + K+ D+G Sbjct: 8026 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 8084 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y+ T N G + S ++V + + ++ S + + +G +L + Sbjct: 8085 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8144 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597 R T++ P+ + V +D +P + A N +G Sbjct: 8145 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8188 Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657 E PV P P D++V + + MT+ + PP L Sbjct: 8189 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8232 Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712 ++G +G + C + + P TYT + E VR + + Sbjct: 8233 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8290 Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 EP T P P S+ G + + +I+G P+PT+ W++D Sbjct: 8291 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8344 Score = 39.7 bits (91), Expect = 0.029 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L I+ G GR G P+P+V+W ++ + R + T +L D Sbjct: 10456 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10514 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 GKY N +G+R+ ++ V + G PV + F + W Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10566 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221 +K+ ++++ ++G+ V + + + +VS + + IH Sbjct: 10567 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615 Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273 N G+ LV + SM A+ + D+ ++ V E ++ D K Sbjct: 10616 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10668 Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317 +TN I ++ + S A +K+ C R + P PP Sbjct: 10669 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10728 Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373 + +K K SP P+ S +T Q R + G V G+E R Sbjct: 10729 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10788 Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420 A P + P T+ G +D K + G+ D A K +P Sbjct: 10789 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10848 Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 + Q +K T++ + G+P P+V W E + I+V GS L + Sbjct: 10849 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10905 Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499 A D G YS T N G + S Sbjct: 10906 NAAHEDGGIYSLTVENPAGSKTVS 10929 Score = 39.7 bits (91), Expect = 0.029 Identities = 23/81 (28%), Positives = 34/81 (41%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VVK G RF I G P P W ++ +V N VL I + D G Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11207 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y V N +G +++ L++ Sbjct: 11208 EYQITVSNAAGSKTVAVHLTV 11228 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 +++ A + + + P V EAP L + + ++ G +A+ +G P Sbjct: 17621 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17680 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P++TW R T + ++ G+ T L I D GKY + N SG++ V Sbjct: 17681 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17737 Query: 121 LTV 123 + V Sbjct: 17738 VKV 17740 Score = 39.7 bits (91), Expect = 0.029 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L L VS PP I W+ G L + I ++ SL + ++K D G Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23141 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y A+N +G+ + V V D P Sbjct: 23142 KYTIEAENQSGKKSATVLVKVYDTP 23166 Score = 39.3 bits (90), Expect = 0.037 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779 P F +SV G + I+G P P V W RDG+ + T ++ ++ L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839 + V ++G+Y + N G+ + L+++ +A P + L + Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116 Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893 G R G P + DG +++ L ++ E Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174 Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953 ++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231 Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005 RS+ + G + +P K PP P P RS + K +L + S Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287 Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032 S P+ + + P PV + PA Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V + P KP D+ V+EG P P V W KD + ++ S + Sbjct: 8004 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8063 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 D + L + D YT N LG AT + + V Sbjct: 8064 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%) Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575 SV ++ G+ + V G PVP W + R + +EL I+DAL Sbjct: 8737 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8796 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 +DHG Y A N+ G +A V V + +L + P + L SD + Sbjct: 8797 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8851 Query: 636 DGSQVT 641 GS++T Sbjct: 8852 GGSEIT 8857 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785 G + I I G P P W DGKA KD H E +N V +++ + + Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9510 Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810 H G+Y I KN+ G+ +C+V +M Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVM 9537 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725 D HFE G H + + G ++ E S G + + V P P + Sbjct: 16123 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16179 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785 ++ G+S + I G P PT+ W++ + L +T E+ + +L +K Sbjct: 16180 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16235 Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809 +G Y + KN GE S V++ Sbjct: 16236 RVDSGNYILKAKNVAGERSVTVNV 16259 Score = 38.9 bits (89), Expect = 0.049 Identities = 21/81 (25%), Positives = 35/81 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + V G + + +V G P P++ W G + + Q + L I+E D G Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605 Query: 692 TYTCEAWNSAGEVRTQAVLTV 712 Y A NS+G + A++ V Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV 11626 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 SV A G+ V + G P PTV W +D K L D + + + L + +V Sbjct: 20908 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20966 Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 G+Y + ++N VGE SS ++ PA+C+ L Sbjct: 20967 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21000 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT + Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21265 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 +NA+ +++ V L P PSKP PI Sbjct: 21266 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21292 Score = 38.5 bits (88), Expect = 0.064 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%) Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 G E+ T + PAP P PP ++ ++ V GESV L ++G T TW + Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 QI+ S ++ ++L I A E G +T N+ G+ L V Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986 Score = 38.5 bits (88), Expect = 0.064 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 PV ++P P + + +++M G + + V+G P P +W E+ + + Sbjct: 8720 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8778 Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 + GT+ L I++ +D G Y A NS G Sbjct: 8779 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811 Score = 38.5 bits (88), Expect = 0.064 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98 L +K G T + E VRG P P+V W ++ +T R +D + FSL Sbjct: 11839 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11896 Query: 99 EDRGKYTCEATNGSGA 114 D GKY ATN +G+ Sbjct: 11897 SDGGKYVVTATNTAGS 11912 Score = 38.5 bits (88), Expect = 0.064 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%) Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++ Sbjct: 13317 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13369 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515 + +L D+G Y T N+ G+ + ++V + V E++ Sbjct: 13370 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13429 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V + +I+G ++ V+ R +W + T E + + Sbjct: 13430 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13480 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 + AEN G + + +R + V S+ P+ DLKV Sbjct: 13481 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13521 Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691 S+ + ++ G P G+ I DF E+ Q SL +Q + T Sbjct: 13522 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13575 Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744 T+ A N GE T + +TV D P K A + + I Sbjct: 13576 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13634 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P+V W + L DT V + TL++ Q AG+Y I LKN G Sbjct: 13635 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693 Query: 805 CQVSL 809 +S+ Sbjct: 13694 GTISI 13698 Score = 38.5 bits (88), Expect = 0.064 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 PAF L + G K + G P P VTWH++ P+ R + L Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15834 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I ED G Y + TN +G T+ + V G + + D + Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15889 Query: 153 PSIWGECPPKF 163 WG PPK+ Sbjct: 15890 ---WG--PPKY 15895 Score = 38.5 bits (88), Expect = 0.064 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 RD VV G R + + G P P + W + D+ I ES +I + D LI+ D Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17318 Query: 1875 DDDAKYTCKAVNSLG 1889 D +Y +A N G Sbjct: 17319 IDGGQYILRASNVAG 17333 Score = 38.5 bits (88), Expect = 0.064 Identities = 22/83 (26%), Positives = 37/83 (44%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + K G I+GRP P+VTW + L+ + RVS++ L + + D G Sbjct: 22285 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22344 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y + N +G + S + + G Sbjct: 22345 RYFLTLENTAGVKTFSVTVVVIG 22367 Score = 38.1 bits (87), Expect = 0.083 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%) Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 PV W+ +N +PI+ + E GV +P+ A NA+G Sbjct: 7953 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7996 Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658 + S SE ++ P KPT + D+ V++G ++++ V P P V W Sbjct: 7997 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050 Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717 +G E++ S+ + L + + D G YT N G V + P Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8108 Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771 P K +T S SC + +P P +H++ + + + T + V+ Sbjct: 8109 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8158 Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 E+ + +K + P + + N+VG Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8188 Score = 37.7 bits (86), Expect = 0.11 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%) Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672 PT + L D +KV G V + V+G P P++ W N I++ D Sbjct: 9023 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9082 Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704 + + L I + ED GTYT A N G V Sbjct: 9083 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9114 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/73 (27%), Positives = 33/73 (45%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V++K G+ R ++GRP P + W K L+ +A++ + + L + D G Sbjct: 15099 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15158 Query: 230 VYTCLVVNGSGKA 242 YT N G A Sbjct: 15159 AYTLTATNPGGFA 15171 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86 +AP L P+ + + G T E +RG P P V W ++G+ + + R + I+ Sbjct: 18331 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18390 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 T +LV+ D G+Y + +N G + + + + V Sbjct: 18391 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18426 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663 PS+ T PI ++ + D+K D G + + ++G P P + W +G EI Sbjct: 19399 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19458 Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 +E L +++ DTG Y N AG Sbjct: 19459 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19497 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/83 (24%), Positives = 38/83 (45%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 + G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21657 Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191 AKN +G A+ +V V D P Sbjct: 21658 TVEAKNASGSAKAEIKVKVQDTP 21680 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1876 ++++ G R + G P P VW K++ + + R + D G S LII D D Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8798 Query: 1877 DAKYTCKAVNSLGEATCTAELIV 1899 +Y A NS G A + V Sbjct: 8799 HGRYVITATNSCGSKFAAARVEV 8821 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+ Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11604 Query: 790 GQYEILLKNRVG 801 G+Y I KN G Sbjct: 11605 GKYIISAKNSSG 11616 Score = 37.4 bits (85), Expect = 0.14 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L +V G P+P ++W +G +P + + + + L + +D G YT Sbjct: 12938 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12997 Query: 585 AENALGQVSCSAWVTVHEK 603 AEN+ G S + + V +K Sbjct: 12998 AENSSGSKSATIKLKVLDK 13016 Score = 37.4 bits (85), Expect = 0.14 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%) Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78 VDP R+ P + + + G + K + + G P P + W + Q +++ R Sbjct: 16166 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16217 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + T SL + D G Y +A N +G R VTV + V G V+S Sbjct: 16218 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16276 Query: 139 TLGDR 143 ++ Sbjct: 16277 VTAEK 16281 Score = 37.4 bits (85), Expect = 0.14 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480 V+ + + G P PE+ W R+EG +V + G +Y L + Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17716 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y N+ G S T++V + LAV EV + ++ + +I+G V Sbjct: 17717 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17776 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 + R YA + + +++ + +AEN G Sbjct: 17777 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17824 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 V V + + +E P P K T + D SQ + ++ PE Sbjct: 17825 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17865 Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703 H+G + +GT+ +C V +G + +A+N G+ Sbjct: 17866 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17921 Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762 + + D T QP + + G+ + I + G P P + W++DG+ L Sbjct: 17922 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 17980 Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 K T V + L +K+ G+Y + N G + +S+++ Sbjct: 17981 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029 Score = 37.4 bits (85), Expect = 0.14 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%) Query: 1791 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 D S + +A+E+ +P F S+ + L V G++ G P P V+W K D Sbjct: 19795 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19853 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 +R + D SL I + +D KYT N L A+ T L+V+ ++ Sbjct: 19854 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19904 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97 P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ + Sbjct: 20110 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20168 Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137 D G+Y A N SG + + + V G V+S Sbjct: 20169 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y + Sbjct: 21601 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21659 Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819 KN G ++ + +Q++ + + Sbjct: 21660 EAKNASGSAKAEIKVKVQDTPGKVV 21684 Score = 37.0 bits (84), Expect = 0.19 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%) Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137 + H G + + P + V V EG+ +C+V+ P + W LNG+ Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834 Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195 ++ +K + +G + + I D G K A+N G E ++ + S Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893 Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 +APE RP+ + + + +P T K + + + +KV ES Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949 Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290 EL K + IT +K RK+ + E + K +E Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009 Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340 G K+TI L+ E + + +G A + VV KPDP Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400 WY + IE D W E C ++D+ + Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101 Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451 V+AIN+ G + Q +L T ++ ++ KD + + + EP V + Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161 Query: 1452 VTINTEQKVSDFY 1464 E D Y Sbjct: 2162 YKDGMEVHEGDKY 2174 Score = 37.0 bits (84), Expect = 0.19 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%) Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994 P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + + Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916 Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054 +T K V K + + K E + + + T + A Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967 Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101 LKS K+E +++ + H T+ EK++ E + T P FK Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027 Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152 +++Q V +G + +V P W NG K ++ + E ++ Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178 C + I ED A N AG+ Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + VSG PPP V W N NE ++ E S+ I+ G Y+ Sbjct: 10167 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10224 Query: 697 AWNSAGEVRTQAVLTV 712 A N AGE + ++ V Sbjct: 10225 AKNEAGERKKTIIVDV 10240 Score = 37.0 bits (84), Expect = 0.19 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1870 T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I Sbjct: 11541 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11597 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA 1895 + D KY A NS G A +A Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSA 11622 Score = 37.0 bits (84), Expect = 0.19 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 1800 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1853 V E+ VK K + DL+ V G R + + G P PEV W KD + +R Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874 Query: 1854 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++ D + S ++ D KY A N+ G A + V Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921 Score = 37.0 bits (84), Expect = 0.19 Identities = 22/92 (23%), Positives = 40/92 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G ++ + V G P P W +E+ S + + L I++V +D+G Sbjct: 12536 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12595 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723 Y+ A NS+G + + V + QP F Sbjct: 12596 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12627 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 + + G + R I+G P PEV W K D IR++ + SL++ +V D Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16636 Query: 1878 AKYTCKAVNSLG 1889 KYT NS G Sbjct: 16637 GKYTLTLENSSG 16648 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 1809 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1865 P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20556 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 S++I D + Y K N++G A+ T Sbjct: 20557 SILIKDADRLNSGCYELKLRNAMGSASAT 20585 Score = 37.0 bits (84), Expect = 0.19 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V + G + I+G+P P + W K + LQ +A V V + + I ++ + G Sbjct: 20510 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20569 Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254 Y + N G A SA + +Q LD Sbjct: 20570 CYELKLRNAMGSA--SATIRVQILD 20592 Score = 36.6 bits (83), Expect = 0.24 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%) Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 RF A E R + PK T +VV G+ P+ + W K N PL Sbjct: 6610 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6669 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + +E+ ++LE + D G Y ++ N GKA L + Sbjct: 6670 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6714 Score = 36.6 bits (83), Expect = 0.24 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223 V+EG KI G P P +TW K P +P + V + N + V L I Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9814 Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252 + D G+YT VN G AS L++ G Sbjct: 9815 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9843 Score = 36.6 bits (83), Expect = 0.24 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586 G L ++G P P++TW + AR ++L I++A ED G Y+ E Sbjct: 10861 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10920 Query: 587 NALGQVSCSAWVTVHEK 603 N G + S V V +K Sbjct: 10921 NPAGSKTVSVKVLVLDK 10937 Score = 36.6 bits (83), Expect = 0.24 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%) Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643 A+N G +S + T + K EY P PT L + G + + Sbjct: 13978 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14028 Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703 + + G P P+ W G +I+ S+ T L I+ +D G YT A N G Sbjct: 14029 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14088 Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 +TV + P IS + A+L Sbjct: 14089 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14119 Score = 36.6 bits (83), Expect = 0.24 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20175 Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725 A NS+G + ++ + P T P IS Sbjct: 20176 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208 Score = 36.6 bits (83), Expect = 0.24 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 1794 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1850 +AF + +E P ++P T +++ GS D I G P P+V W ++ ++ Sbjct: 22259 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22317 Query: 1851 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 E+ I +D +L + D D +Y N+ G T + ++V Sbjct: 22318 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365 Score = 36.2 bits (82), Expect = 0.32 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128 NC+ G D N K S P + L+DV V G+ C++S + Sbjct: 5795 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5853 Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174 + W L GK L+ + ++ EG + ++++ ED G + AK+ Sbjct: 5854 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5899 Score = 36.2 bits (82), Expect = 0.32 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%) Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G Sbjct: 10471 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10529 Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 + V V P SF V KD VI Sbjct: 10530 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10559 Score = 36.2 bits (82), Expect = 0.32 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 ++ + G++ + + G P PT+ WLR K + +++ E+ + L++K Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17320 Query: 789 AGQYEILLKNRVGECSCQVSL 809 GQY + N G S V++ Sbjct: 17321 GGQYILRASNVAGSKSFPVNV 17341 Score = 35.8 bits (81), Expect = 0.41 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P T L V +EG + + IT + V W N + + + L I Sbjct: 4368 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4425 Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250 VN +D G Y C +N SGK + SA+L++ Sbjct: 4426 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4456 Score = 35.8 bits (81), Expect = 0.41 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%) Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 T S ++ + E ++ +A N G + ++ L V + D P Sbjct: 8979 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9023 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204 ++ R S+ G+ + VK G+ +TG P P++ W K ++ Sbjct: 9024 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9073 Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260 + VS L I ++D G YT N G + + + S R+ Sbjct: 9074 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9133 Query: 261 VRETKA 266 V + KA Sbjct: 9134 VTDIKA 9139 Score = 35.8 bits (81), Expect = 0.41 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G +V I G P PT W DG + K H+ V + L +K G+Y+I Sbjct: 11153 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211 Query: 795 LLKNRVGECSCQVSL 809 + N G + V L Sbjct: 11212 TVSNAAGSKTVAVHL 11226 Score = 35.8 bits (81), Expect = 0.41 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 EAP +L P L IK G T + G P P+ +W + G+ I + Sbjct: 14002 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14061 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + + +A + D G+YT ATN G + V++TV Sbjct: 14062 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14097 Score = 35.8 bits (81), Expect = 0.41 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584 G + ++ V G P P +TW Q ++ + A L+I + + D G Y Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 A N +G+V + VH+ P PT PI Sbjct: 14768 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14794 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16638 Query: 104 YTCEATNGSGARQVTVELTV 123 YT N SG + V + V Sbjct: 16639 YTLTLENSSGTKSAFVTVRV 16658 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P+ LP +K K + +G P+ V W ++GQ + R + + SL Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19081 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I +ED G Y +N +G+ +TV +T+ Sbjct: 19082 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19110 Score = 35.8 bits (81), Expect = 0.41 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 1833 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 +G P P V W KD++++ + I+ + D + L I V +D KY N +GE Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20980 Score = 35.8 bits (81), Expect = 0.41 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142 +T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + + Sbjct: 26943 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27002 Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + L ++ I +D GLY N+ G + + + Sbjct: 27003 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048 Score = 35.4 bits (80), Expect = 0.54 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L ++ V+E + L C+VS P A +IW + + T + EG + I+ Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6151 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219 A ED G Y C R P S +D Sbjct: 6152 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6170 Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279 VK + + I P++ ++ GE E ++ + W + K ++ Sbjct: 6171 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6220 Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 + V L + A + G Y ++V G+ +A +LTV++K Sbjct: 6221 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6267 Score = 35.4 bits (80), Expect = 0.54 Identities = 16/82 (19%), Positives = 37/82 (45%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 ++ ++ G+ + + +G+P+P+V+W K + R + LE + D Sbjct: 10455 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10514 Query: 229 GVYTCLVVNGSGKASMSAELSI 250 G Y +V N +G ++++ Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV 10536 Score = 35.4 bits (80), Expect = 0.54 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676 KP + L G+ L V G + + V G P PEV W + ++ S + R Sbjct: 11828 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11885 Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + + D G Y A N+AG A + V Sbjct: 11886 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921 Score = 35.4 bits (80), Expect = 0.54 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 + +A+NA G +S + T + K E LP P + + V G Sbjct: 17221 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17271 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 + V G P P + WL EI+ES + + L +++ D G Y A N Sbjct: 17272 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17331 Query: 701 AG 702 AG Sbjct: 17332 AG 17333 Score = 35.4 bits (80), Expect = 0.54 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + +K G K + G P P ++W ++G I R + T L + D Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19485 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157 G+Y N +G R V V V G ++ ++ S P + I Sbjct: 19486 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19545 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205 K T + EG++ SCK+T LKGN + +P Sbjct: 19546 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19598 Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 V++ + V LEI V ++ + + C S S + I+ + + Sbjct: 19599 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19656 Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314 +VR K D+R + T + E ++ + AA S S R P + P Sbjct: 19657 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19712 Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373 PP + K+ +S K + A P+ + + + + S G E Sbjct: 19713 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19772 Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430 A + R +G+ D S +++ +I E + + F ++ VK + Sbjct: 19773 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19831 Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490 G P P V W T +R + ++ + S L + A DSG Y+ T Sbjct: 19832 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19888 Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526 N S + ++V + V K+ AV+ Sbjct: 19889 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19924 Score = 35.4 bits (80), Expect = 0.54 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V++G + R + I G+P P W K + A ++ SE + L I ++ D G Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23831 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y ++ N GK ++ ++ + G Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIG 23854 Score = 35.4 bits (80), Expect = 0.54 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1867 P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26059 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 I D DD Y N GEA+ A L V Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D++V E A+F+C++ P W K Q I F++ D + S++I Sbjct: 5470 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5527 Query: 1871 DVCGDDDAKYTCKA 1884 +D+AKY +A Sbjct: 5528 SAAFEDEAKYMFEA 5541 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 R+VV G + R ++G+P P VTW L A + + + V I + Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10218 Query: 229 GVYTCLVVNGSGK 241 GVY+ L N +G+ Sbjct: 10219 GVYSLLAKNEAGE 10231 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 ++ G + VRG P P+VTW + G + G L+D LVI +D Sbjct: 12246 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12301 Query: 102 GKYTCEATNGSGARQVTVELTV 123 GKY+ N +G + V V + V Sbjct: 12302 GKYSLTLVNPAGEKAVFVNVRV 12323 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 L V G+ D + G P P V W KD ++ + ++ + C+L + V D Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 YT A NS G + T +L V Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013 Score = 35.0 bits (79), Expect = 0.70 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%) Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 VA AP + L+GL DL + + S + + + G P P V W + + Sbjct: 13600 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13659 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721 E +L + + D G YT N AG + T ++ V +P T P Sbjct: 13660 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13710 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%) Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201 D + AP + P+I K G +V + I G+P P+ +W K + Sbjct: 13999 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14048 Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 +PS ++ +L I + D G YT N G Sbjct: 14049 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 +V G ++ + I+G P P V RDG L K T F + T+ LK+ Sbjct: 20113 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20171 Query: 789 AGQYEILLKNRVGECSCQVSLML 811 AG+YEI N G +++++ Sbjct: 20172 AGRYEITAANSSGTTKAFINIVV 20194 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565 V+++ ++ V+K A G L+ + G P P I W + + +Q C + Sbjct: 20499 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20555 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 A + I+DA + G Y NA+G S + V + +K Sbjct: 20556 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20593 Score = 34.7 bits (78), Expect = 0.92 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V P+ W G PV + + E+ G Y Y A N QG Sbjct: 7252 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7298 Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553 S T +++ + E F V L V G L +V G P P+ITW Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358 Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 + Q R T E + + I D+ D GTY A N G+ + V V +K Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7411 Score = 34.7 bits (78), Expect = 0.92 Identities = 16/67 (23%), Positives = 28/67 (41%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + G P P + W+ E+ + + SL +++ D+G Y + Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16245 Query: 697 AWNSAGE 703 A N AGE Sbjct: 16246 AKNVAGE 16252 Score = 34.7 bits (78), Expect = 0.92 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451 +SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G Sbjct: 17232 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17290 Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 + E+ L + A D G Y ASN G S Sbjct: 17291 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17336 Score = 34.7 bits (78), Expect = 0.92 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ AT + ++G PEP+V W + +T + + +F+ LVI V D G Sbjct: 18747 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18802 Query: 103 KYTCEATNGSGARQVTVELTV 123 +Y N SG++ V + V Sbjct: 18803 RYNLTLENNSGSKTAFVNVRV 18823 Score = 34.7 bits (78), Expect = 0.92 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 +KP V + D +G P V W KD Q+++E+ + + S Sbjct: 19021 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19079 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + +D Y NS G T +IV Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112 Score = 34.3 bits (77), Expect = 1.2 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 ++D V E F+C++ + WF+++++I +S + I +D +L I D Sbjct: 6274 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6331 Query: 1875 DDDAKYTCKAVNSLGE-ATCTAELIVE 1900 DD A Y N GE A LIVE Sbjct: 6332 DDQANYNVSLTNHRGENVKSAANLIVE 6358 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%) Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470 +A PK ++ Q V + + PK E WF E P+ + +I+ + S Sbjct: 6625 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6681 Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523 +L+A+ D G Y N G+ L+ V L V E S+ + Sbjct: 6682 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6740 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549 + +G ++ V + R TW+L Sbjct: 6741 PLTDGGSKIIGYVVERRDIKRKTWVL 6766 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57 G+ L S +K +S DPS + PLT AF+ P +L K+G + Sbjct: 6987 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7044 Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 GYP P TW + + +G R + + LVI D+G YT + N Sbjct: 7045 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7099 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225 G + VK G R + G+P P+V W K L S RV + + + + Sbjct: 11837 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11896 Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250 D G Y N +G A +++ Sbjct: 11897 SDGGKYVVTATNTAGSFVAYATVNV 11921 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%) Query: 1812 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1871 S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D Sbjct: 17656 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17711 Query: 1872 VCGDDDA-KYTCKAVNSLG 1889 C +DA KY K NS G Sbjct: 17712 NCDRNDAGKYILKLENSSG 17730 Score = 34.3 bits (77), Expect = 1.2 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%) Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77 P V + E P + L R + +++G + ++G P P W + GQ I+ Sbjct: 23750 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23807 Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126 R ++ T LVI D G Y N G + V +++ V GS Sbjct: 23808 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23855 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G + I ++G P PTV W + + L ++ + ++V+K Q H Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10218 Query: 790 GQYEILLKNRVGE 802 G Y +L KN GE Sbjct: 10219 GVYSLLAKNEAGE 10231 Score = 33.9 bits (76), Expect = 1.6 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%) Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 +RG PVP W +G I ++ + + L I++ L D G Y NA G + Sbjct: 11162 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11221 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + +TV + P PT PI ++D + MT +S PP + Sbjct: 11222 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11258 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 G A R + + G P P + W KD + + + +I D + +L+ D D YT Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15162 Query: 1883 KAVNSLGEA 1891 A N G A Sbjct: 15163 TATNPGGFA 15171 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%) Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70 +P+ V P E +LPP + + I+ T + ++G P P+V W R+ Sbjct: 15469 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15526 Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 G L I T S L++ V+ D GKY N SG++ V + V Sbjct: 15527 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15576 Score = 33.9 bits (76), Expect = 1.6 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G + + V + G P PEV W EI+++ T SL + V D+G Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16637 Query: 692 TYTCEAWNSAG 702 YT NS+G Sbjct: 16638 KYTLTLENSSG 16648 Score = 33.9 bits (76), Expect = 1.6 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%) Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75 +++ P V + +T E +P + ++ G E +G P+P ++W ++G P+ Sbjct: 21175 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21234 Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 F+ +L I +E GKYT N ++ V +TV Sbjct: 21235 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21279 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%) Query: 1796 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1845 + E++AE ++P I DLE+ + G++ R + G P P + W K Sbjct: 23056 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23110 Query: 1846 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 Q I + ID E + LI+ V D KYT +A N G+ + T Sbjct: 23111 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23157 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D V EG A F C++ + VVWFK+D + SR I E L + Sbjct: 5204 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5261 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +V DD ++ + + E + TA+L V Sbjct: 5262 EVTLDDISQIKAQ----VKELSSTAQLKV 5286 Score = 33.5 bits (75), Expect = 2.0 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+ Sbjct: 5559 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5616 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCT 1894 D+ DD ++ +A+ EA T Sbjct: 5617 DLSIDDTSQIRVEAMGMSSEAKLT 5640 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/72 (27%), Positives = 32/72 (44%) Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244 TG P+P TW G+ L+ RV + + L I + D G+YT + N S Sbjct: 7047 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106 Query: 245 SAELSIQGLDSA 256 ++++ SA Sbjct: 7107 EIDVNVIARPSA 7118 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%) Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69 S IS+ ++ DP P L ++ + EG R P P V+WH++ Sbjct: 8000 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8051 Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125 G+ + + R + V +V D G YT N G+ ++ + V G Sbjct: 8052 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8106 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582 G L+ VRG P P + W + RS A ++ + A D G Y Sbjct: 11844 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11903 Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621 A N G A V V +K ++ ++ V+ + T Sbjct: 11904 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11942 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96 + L ++ G T + V+G P P++TW + + R LD I+ T F + V Sbjct: 13329 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13384 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 ++ D GKY N G ++ T+ + V Sbjct: 13385 NKYDAGKYILTLENSCGKKEYTIVVKV 13411 Score = 33.5 bits (75), Expect = 2.0 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 VK V S S S DP E P F + + L +K GA+ RG P Sbjct: 19785 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19842 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P V W + + + R +D T SL I + D GKYT N A +T+ Sbjct: 19843 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19899 Query: 121 LTV 123 + V Sbjct: 19900 VKV 19902 Score = 33.5 bits (75), Expect = 2.0 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572 S + K V G F + RG PVP + W +P R+ + L I++ Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19874 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600 A D G YT +N L S + V V Sbjct: 19875 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19902 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19881 Query: 692 TYTCEAWN 699 YT N Sbjct: 19882 KYTLTIQN 19889 Score = 33.1 bits (74), Expect = 2.7 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G KL+ + +LSV+ ++ I R+L E FE + + Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W+ + I ++ ++ + + L + + ++D GKYT A G + +L Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 TV G +SK L D+ V E Q F Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C++ P + WL+ L + + + L I DD+G YT V Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653 Query: 242 ASMSAE 247 A + E Sbjct: 2654 AKLKVE 2659 Score = 33.1 bits (74), Expect = 2.7 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 1776 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1821 S T +++E + ++ + L+ +++ K VK PYF+ + D V Sbjct: 5244 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5303 Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E C++ D V WFKD + I S + I D L I D +Y Sbjct: 5304 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5360 Query: 1882 CKAVNSLGEATCTAE 1896 C +A T E Sbjct: 5361 CDCGTDKTKANVTVE 5375 Score = 33.1 bits (74), Expect = 2.7 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%) Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501 K EV W L V Q ++ + H L + + RD G Y A + + + Sbjct: 6567 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6623 Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561 + AP + +D V G+ + P W +P+ Sbjct: 6624 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6675 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591 A I +A D G Y + +N G+ Sbjct: 6676 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6705 Score = 33.1 bits (74), Expect = 2.7 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160 + V G+ + + V+ P I W+ N + K T + +++E + +SI KA Sbjct: 9036 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9095 Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 + ED+G Y A N G + V V D P+ Sbjct: 9096 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9127 Score = 33.1 bits (74), Expect = 2.7 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 1816 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875 R+ + G R I+G P P+V W K+D+ +ID G+ L I + + Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10910 Query: 1876 DDAKYTCKAVNSLGEATCTAELIV 1899 D Y+ N G T + +++V Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934 Score = 33.1 bits (74), Expect = 2.7 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575 +D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D + Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19482 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y +N G S + V +K P P P+ + GL+ Sbjct: 19483 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19524 Score = 33.1 bits (74), Expect = 2.7 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ GA+ + +G P P W + ++ D +FS L + + D G Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22052 Query: 103 KYTCEATNGSGARQVTVELTV 123 KYT N SG++ +T + V Sbjct: 22053 KYTLTVENNSGSKSITFTVKV 22073 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 + D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+ Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373 Query: 1875 DDDAKYTCKAVNSLGEAT 1892 +D Y+ + +LG +T Sbjct: 2374 EDAGNYSF-TIPALGLST 2390 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163 G ++ + + P W +GK K K + L + + I + Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 G Y AKN AGQ +C+V V D P Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKVMDVP 9540 Score = 32.7 bits (73), Expect = 3.5 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1881 GS D + G P+P+++W K D+ + + Y G + + C D KYT Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22747 Query: 1882 CKAVNSLG 1889 N+ G Sbjct: 22748 LTVKNASG 22755 Score = 32.3 bits (72), Expect = 4.6 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 1816 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1873 ++LE++EG A F C I E +P V W +DD+++ + + D L++ D Sbjct: 6187 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6242 Query: 1874 GDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y V +G A A L V Sbjct: 6243 LQDMGTY----VVMVGAARAAAHLTV 6264 Score = 32.3 bits (72), Expect = 4.6 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%) Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 P+ AP + L L + G +T + SG P P+V W + ++ E + H Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495 Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702 + T +L ++++ + D+G Y NS G Sbjct: 10496 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10526 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575 KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+ Sbjct: 15096 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15154 Query: 576 EDHGTYTCLAENALG 590 D G YT A N G Sbjct: 15155 RDSGAYTLTATNPGG 15169 Score = 32.3 bits (72), Expect = 4.6 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584 G + + + G P+P++T +G P++ AE +++++++ D G Y Sbjct: 20119 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20178 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635 A N+ G + V ++ P PT P+ + +++ V Sbjct: 20179 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20225 Query: 636 DGSQVT 641 GSQVT Sbjct: 20226 GGSQVT 20231 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P + L+ +K G+ V + +SG P P + W + E+Q + E S Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20557 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 + I++ ++G Y + N+ G A + VQ Sbjct: 20558 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20589 Score = 32.3 bits (72), Expect = 4.6 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 +P + + + G + + G P P +W G + R ++ + L I Sbjct: 23371 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23429 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 D G+YT E N +G T+++ + Sbjct: 23430 TIRDTGEYTLELKNVTGTTSETIKVII 23456 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 1811 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + D Y+C V T TA+LIVE Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%) Query: 1745 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1797 W K G V+ I + S M +I ++ K G+ + + A L + VS + Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399 Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 + + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1870 ++R L +V G R + G P P+V W K D +R+ Q+D D L+I Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12294 Query: 1871 DVCGDDDAKYTCKAVNSLGE 1890 + DD KY+ VN GE Sbjct: 12295 NSTRDDSGKYSLTLVNPAGE 12314 Score = 32.0 bits (71), Expect = 6.0 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786 R++ G S+ I I G P P V W +D L K+ + E N + FT L++ + Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14467 Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819 + G++ + ++N G+ S V++ + ++ L Sbjct: 14468 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14500 Score = 32.0 bits (71), Expect = 6.0 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 +D+ VV G + I G P P+VVW KD + + E+ +L++ D Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401 Query: 1875 DDDAKYTCKAVN 1886 D +Y K N Sbjct: 18402 TDGGQYILKLSN 18413 Score = 32.0 bits (71), Expect = 6.0 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104 K G+ + + G P P+VTW + R + + +L + D G+Y Sbjct: 22288 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22346 Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164 N +G + +V + V G G VS + E+ WGE Sbjct: 22347 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22398 Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215 T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+ Sbjct: 22399 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22451 Score = 31.6 bits (70), Expect = 7.8 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E S R I+G P P V W K + + ++ N +LI+ D D KYT Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13682 Query: 1882 CKAVNSLG--EATCTAELI 1898 N G E T + +++ Sbjct: 13683 ITLKNVAGTKEGTISIKVV 13701 Score = 31.6 bits (70), Expect = 7.8 Identities = 19/80 (23%), Positives = 30/80 (37%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V +T ++ G P P+V W +G + +E+ L + D G Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y SN G S T++V Sbjct: 18407 YILKLSNVGGTKSIPITVKV 18426 Score = 31.6 bits (70), Expect = 7.8 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694 G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y Sbjct: 18350 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408 Query: 695 CEAWNSAG 702 + N G Sbjct: 18409 LKLSNVGG 18416 >gi|110349715 titin isoform N2-B [Homo sapiens] Length = 26926 Score = 366 bits (939), Expect = e-100 Identities = 238/812 (29%), Positives = 389/812 (47%), Gaps = 79/812 (9%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154 AP FK++L++++V L C+V+ P + W GK + K+ I +G Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + I +D +Y+ A N G + + V+ Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24523 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 P K +P + +R GE V + +G TW K Sbjct: 24524 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24567 Query: 1275 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 + I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP Sbjct: 24568 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24627 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393 P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V + Sbjct: 24628 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24686 Query: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453 L Y+FRV A N +G S+PS+ SE T E + E D+ EV + Sbjct: 24687 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24743 Query: 1454 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513 ++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+ Sbjct: 24744 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24802 Query: 1514 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573 N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E + Sbjct: 24803 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24862 Query: 1574 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633 +++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV Sbjct: 24863 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 24922 Query: 1634 NYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAK 1693 ++ + ATDMWS+G + Y+L+SG++PF+ + + + + N+ +A + FD+EAF EIS +A Sbjct: 24923 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 24982 Query: 1694 DFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1753 DF+ LL K+ K+R+ ++ LQHPWL + + + K + + ++Y +K N V Sbjct: 24983 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25041 Query: 1754 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1813 + R+S I +S G + + +E VS + AV EE HVK Sbjct: 25042 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25089 Query: 1814 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 + CKIE Y +V W+ + + S ++I Y EDG L + D+ Sbjct: 25090 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25134 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 DD Y CK VN GE + AEL V+ + E Sbjct: 25135 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25166 Score = 164 bits (416), Expect = 6e-40 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%) Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122 +VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++ Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310 Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171 + S K+ Q T+ + A E S P T L Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26365 Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y Sbjct: 26366 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26425 Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285 TC V N +G S S +L+I+ + V K + + V++E++ + ++ Sbjct: 26426 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26485 Query: 286 DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 EA ++ SK S + S + +K + RT + Sbjct: 26486 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26545 Query: 337 VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388 T SI + R+ + G GV + EE + T +Q Sbjct: 26546 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26603 Query: 389 LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440 + + +SK + + + S P F S+P+SQ + E Q V F CE+SG Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26663 Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 P PE+ WF P+ ++ + + L + A DSG Y+ A N +GQ CS Sbjct: 26664 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26720 Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560 T + L ++E PS VL+ D LQ S + Q +Q + S Sbjct: 26721 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26762 Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613 EA + A + ++ ++ ++S S+++ + S + Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 26822 Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671 A + P SD+ + +G +T+ +G P PEV W G +I QE FH Sbjct: 26823 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 26882 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 E +L I +V +D G YT N G Sbjct: 26883 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913 Score = 155 bits (391), Expect = 5e-37 Identities = 124/475 (26%), Positives = 201/475 (42%), Gaps = 79/475 (16%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P+ + Q V+ + +F +SG P+P+++W+ E + + D + L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526 L++A D+ Y+C A N G + S +L VE V+ P+ + L+D Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311 Query: 527 EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583 EGQ QC V GT + +++W + P ++ R T +L I +A PED GTYT Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370 Query: 584 LAENALGQVSCSAWVTVHEKKS------------------------------------SR 607 +A NA+GQVS +A +++ +S S+ Sbjct: 3371 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430 Query: 608 KSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656 +E L PV P+K T PIF++ +S+ + G T++V V G P P++ W Sbjct: 3431 INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQW 3490 Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--- 713 NG + S D+ F G HSL I ED G YTC A N G+ A L + Sbjct: 3491 FFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 3550 Query: 714 EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 E H T+ P F+ + + + + G + + G+P PTV W + Sbjct: 3551 EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK 3610 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 + K LC + + T ++ Q +G Y +N +GE +C L++ Sbjct: 3611 ENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665 Score = 134 bits (336), Expect = 1e-30 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%) Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 S + P + S+ P + Q V + KF + +G P+P W +G + Sbjct: 26337 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26396 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 Q G ++ ED G +L + K T DSG Y+CT N+ G +S S L ++ Sbjct: 26397 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26445 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 +KD E Q Q + TP + ++ + Q A + E ++E Q+ L Sbjct: 26446 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26497 Query: 576 -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631 ++ + ++E + S + VHE+ K+S+ SE + A K + + Sbjct: 26498 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26550 Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + +G ++ + ++G +V W+ NG E+ SE++ + G+ +L I++ D G Sbjct: 26551 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751 TC + G V+ Q LT+ + P FIS+PRS + GQ+VL +C I+G+P P Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667 Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 + W ++ + + + + ++ +V++L ++ +G+Y I KN G+CS SLM+ Sbjct: 26668 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726 Query: 812 QNSSARALPRGREPA 826 LP EP+ Sbjct: 26727 -------LPLVEEPS 26734 Score = 122 bits (306), Expect = 3e-27 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++ Sbjct: 23654 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23710 Query: 795 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848 +L+N+ G+ + + + + S P G P +D+ V AD GG+D G Sbjct: 23711 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23766 Query: 849 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906 + W + VRG +++ E R Q L + V+ Sbjct: 23767 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23824 Query: 907 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963 KT L+ + P E +D + + + +V + ++ + K + Sbjct: 23825 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 23883 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022 KT + + PD + ++ A+N +ET A + V P G Sbjct: 23884 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 23939 Query: 1023 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070 L+ + +K + TL KP K D K ++KE +K Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 23999 Query: 1071 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120 +N+ R T + K + G AP +++++DV G+ L CQ Sbjct: 24000 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24058 Query: 1121 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180 + P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E Sbjct: 24059 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24118 Query: 1181 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240 S ++ + P P P K Sbjct: 24119 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24138 Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299 E G ++ L G TW +K +Q SE++ +EN+E+ + L + Sbjct: 24139 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24194 Query: 1300 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG Sbjct: 24195 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24254 Query: 1360 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P + Sbjct: 24255 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24314 Query: 1418 ESELTTVGEKPEEP 1431 S + + E+P Sbjct: 24315 VSSVVIIKSPFEKP 24328 Score = 118 bits (295), Expect = 6e-26 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%) Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680 T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714 I+E F ED+G +TC A N AG V T L VQ Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014 Query: 715 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759 P + P+FI+KP G SV+ C + G+P P V+W + G Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074 Query: 760 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ + Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131 Query: 817 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875 L + ++ + V + G PG+ + + E+E + + K Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186 Query: 876 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932 V R + E+ QE F + L K++ KT E+ L+E E+M + Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242 Query: 933 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981 V+ S + ++ + + ++ V S P+P +++ + DF Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298 Query: 982 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035 R+ L LP + G +A N K NA SG P P+G TL Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350 Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095 +P+ + +L P ++ + A + + + S+ + Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407 Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152 P F K EG+ +V P W +G+ + T +++ ++G+ Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212 S+ I A P D G + VA+N AG++ S +TV+ Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504 Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272 + + P ++ ++ ++ G +E+ + TG W+ Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544 Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327 K I ++ +++E ++ + L I + + YT NK G + + +VN+ V Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604 Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348 +P+P P GT A +I + L Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631 Score = 115 bits (288), Expect = 4e-25 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483 + E Q + + ++G +V W L G + E Y +GS +K A RD G Sbjct: 26553 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26608 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 +C + +G + C + L + + + AP+F S + + EGQ+ + C + G P P Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26666 Query: 544 RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 I W N PI + + V L I++A D G YT A+N GQ S +A + V Sbjct: 26667 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 LP+ +P+ + L+ D + GS + +VQ+S + + Sbjct: 26727 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26772 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 + + F Q +QE F E + + N ++ + ++ G Sbjct: 26773 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 26831 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779 P + P ++ G+ + ++CA G+P P V W G+ + ++ G F + +D+ TL Sbjct: 26832 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 26891 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813 ++ VQ G Y + L N G S V++ +++ Sbjct: 26892 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 26925 Score = 115 bits (287), Expect = 5e-25 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%) Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222 F +++ + EG F CK++G P P++ W K R+ E+ M L+ Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297 Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282 G+AS+ + + + +F K N I Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330 Query: 283 SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342 KL +E AA G+P + +P S++ S SPR+ ++P+ Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369 Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402 R+ P +P R PA PA PG ++ R Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408 Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 P F KP S + E QT +F +V G P PE WF +G + Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522 V ++ G+ L ++ A DSG ++ A N G+ S S L VE + +V P F LK+ Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577 + EG ++ G P P I WL N P +Y + E G A L I + +D Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578 Query: 578 HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617 YT A N G+ C V V + + + ++P AP Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638 Query: 618 -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662 K P F + L+ L++ +++ G+P V WLH+G Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714 ++ + SL + D+G TC A N G T A L V++ Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758 Query: 715 ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744 H+G +P + P V G++ C + Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876 Query: 805 CQVSLMLQNSS--ARALPRGREP 825 +V L +Q L R EP Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899 Score = 113 bits (282), Expect = 2e-24 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 +K S RK E L + AP + +V G + V P EV W HNG Sbjct: 25856 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 25915 Query: 662 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682 E+QES D H + GT ++C Sbjct: 25916 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 25975 Query: 683 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718 + VFPE T T EA +S EV++Q T + H Sbjct: 25976 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26035 Query: 719 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752 + ++KPRS+T G+S SC G+P PTV Sbjct: 26036 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q Sbjct: 26096 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154 Query: 813 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848 + + ++ R + P +++ Sbjct: 26155 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26214 Query: 849 LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900 L P + +L+ E +++ VL+ + T + +++ Q + Sbjct: 26215 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274 Query: 901 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954 ++ L+E D + EI E + NLQ + K++ E+ K+ ++ D + Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334 Query: 955 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983 S + +K K P P P P+P T D ++ Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394 Query: 984 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015 + GGK KL + G SS+ L KA++ ++ Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26454 Query: 1016 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067 + Q + + P A E + A +E +K M AK E L + ASK EE+ Sbjct: 26455 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26511 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 KK + H T + SE T K + + EG++L+L+ ++ Sbjct: 26512 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26569 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W LNG L ++ GS +++I++A D G+ C++K G +C +T+ Sbjct: 26570 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247 + E+ SDA P I P Q Sbjct: 26630 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26646 Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 + G++V +++G W K I S ++ + S N L I A G Sbjct: 26647 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26706 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S Sbjct: 26707 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26766 Query: 1368 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423 + S++ + + + S + Q + E + + + G S +Q S++ Sbjct: 26767 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26824 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEV 1447 G + PK E SD E +V Sbjct: 26825 AGIRGIPPKIEALPSDISIDEGKV 26848 Score = 112 bits (279), Expect = 5e-24 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99 +N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311 Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155 D G YT A+N G + +L VE A LG P TL R +P +R I Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369 Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179 P F K EGQ R Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429 Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238 F K+ GRP P+ W G + V +++G Q L I D G +T + N Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489 Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297 +G++S+S L+++ ++ FV + K N I + S+L+ A + N Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538 Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339 W NS P + ++E K + V Q Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592 Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395 T + ++ +PEP ++ P G R K A P P Q D+ Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453 K ++ P F+ K S +K F C ++ G P V W +G P Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698 Query: 454 VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502 + + + + G L A +RDSG +C A+N G S TL Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757 Query: 503 -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536 ++E L M + + V D V+EG+ +C Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817 Query: 537 VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594 V G P P++ W LNGQ I+ ++ G+ L I D D G AEN G + Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877 Query: 595 SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + + +++ R +L AP +P + G +V + T + E Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929 Query: 654 VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694 V+ L I +ESE+ F++R + S E + E Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738 E + E+ + + E T P F + +S T G Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049 Query: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798 + G P P W ++G + + + ++V LV++ V + + N Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109 Query: 799 RVGECSCQVSLMLQ 812 GE S L++Q Sbjct: 2110 IAGETSSHAFLLVQ 2123 Score = 111 bits (278), Expect = 6e-24 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 +PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L Sbjct: 12401 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12459 Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355 I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+ Sbjct: 12460 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12519 Query: 1356 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE Sbjct: 12520 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12579 Query: 1415 PSQESELTTVGE--KPEEPKD 1433 P ++ P EPK+ Sbjct: 12580 PLTSPKMVAQFPFGVPSEPKN 12600 Score = 110 bits (275), Expect = 1e-23 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567 AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+ Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I + G Y+ A N GQ + +A + V K+E AP P F+Q Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168 Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713 ED+GTY+ A NS G + A L VQ Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 109 bits (272), Expect = 3e-23 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%) Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89 T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58 Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144 S L I AV + + G+Y+ +ATNGSG T EL V+ A Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PP F +L + V++G R ++TG P P V + + +Q S Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252 +S++ + L I +D G Y+ N G+A+ +AEL +QG Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207 Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + +A S R+T+ + + ++ + E +D AA + +P R PP + Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263 Query: 312 SQPQPP 317 P PP Sbjct: 264 RSPTPP 269 Score = 109 bits (272), Expect = 3e-23 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y + Sbjct: 7265 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7323 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426 E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T + Sbjct: 7324 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7383 Query: 1427 KPEEPKDEVEVSD 1439 P P +E SD Sbjct: 7384 DPPGPPTRLEPSD 7396 Score = 105 bits (262), Expect = 4e-22 Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%) Query: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 +F + +V E + F CEVS P V W + ++ + I++ ++ H L + Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 R D+G Y+ A + +L V S+ K+ VIE Q V++ Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121 Query: 535 CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589 V V W +G I + + E + + I + D G YT +A Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 +R S L AP P LQ L + V G +SG Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 P P++ W + F G +++L + E FPED YTCEA N G T A Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279 Query: 710 LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 L+V+ P D P + I+ + S GQ C ++G + +D K Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 K + F + Q ED + L + + P G Y + N VG+ S +L L+ Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388 Score = 104 bits (260), Expect = 7e-22 Identities = 104/484 (21%), Positives = 179/484 (36%), Gaps = 53/484 (10%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PP+ +L V V+ G+ RF I+GRPQP+++W K L + L Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 + +D VYTC N G A+ SA LS++ V E + + ++ +I Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVSPDQEMPVYPPAII 3302 Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVL 338 + + E C W + + +P R ++ +D+ + Sbjct: 3303 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3362 Query: 339 QKTSSSITLQAARVQPEPRAPGLGVLSPSG-------EERKRPAPPRPATF-PTRQPGLG 390 + + + + V L + +P +E + ++F + GL Sbjct: 3363 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLH 3422 Query: 391 SQDVVSKAANRRIPM-----------EGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG 439 S ++ N + + + +++ P F + + ++ V G Sbjct: 3423 SAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIG 3482 Query: 440 IPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCS 499 IPKP++ WF G + V+ D H L +L + D G Y+C ASN G+ CS Sbjct: 3483 IPKPKIQWFFNGVLLTPSADYKFVF-DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICS 3541 Query: 500 WTLQVE-----------RLAVME--------VAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 L++ AV + P F LK +G + + +V G Sbjct: 3542 AYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 3601 Query: 541 PVPRITWLLNGQ----PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596 P P +TW + + Y G + D ED G Y C AEN LG+ +C+A Sbjct: 3602 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3661 Query: 597 WVTV 600 + V Sbjct: 3662 ELLV 3665 Score = 102 bits (253), Expect = 5e-21 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 +++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A Sbjct: 20379 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20438 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG Sbjct: 20439 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20498 Query: 1361 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 + + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP Sbjct: 20499 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20555 Query: 1417 QESEL 1421 + + Sbjct: 20556 ESDSV 20560 Score = 101 bits (252), Expect = 6e-21 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%) Query: 1236 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292 +PP + ++ E V+AG +V + G T W +I+ EH VE Sbjct: 11009 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11068 Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352 S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11128 Query: 1353 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411 DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G Sbjct: 11129 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11188 Query: 1412 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469 P +S T K P P + V+D E V + + ++ +Y +E R Sbjct: 11189 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11246 Query: 1470 LGSGKFGQV 1478 +GK+ +V Sbjct: 11247 EVTGKWVRV 11255 Score = 101 bits (252), Expect = 6e-21 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++ Sbjct: 16043 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16099 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16159 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16219 Query: 1410 YGTSEPSQESELTTVGE--KPEEPK 1432 YG EP + + P+ PK Sbjct: 16220 YGVGEPLESEPVVAKNPFVVPDAPK 16244 Score = 101 bits (251), Expect = 8e-21 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%) Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302 F + VRAG S+ LF G T W K + S + +++ S LT+ + Sbjct: 21866 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 21923 Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362 G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+ Sbjct: 21924 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 21982 Query: 1363 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421 + Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E Sbjct: 21983 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22042 Query: 1422 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471 E+P P+ D V+ S +P+ D + QK SDF+ +E Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22101 Query: 1472 SGKFGQVFRLVEK 1484 V RLVEK Sbjct: 22102 KQLTFTVERLVEK 22114 Score = 100 bits (250), Expect = 1e-20 Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%) Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119 +V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG + Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4327 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 +LTV A PV+ + K+ + V G + + Sbjct: 4328 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4355 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F+C+I P + W K + S + S+ + LEI D G YTC N Sbjct: 4356 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415 Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294 G S +A L ++ G + R + E K + ++EV +V+ K + + + K Sbjct: 4416 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4472 Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354 + P PP P+P E ++ + R P+ + + +I L A +P Sbjct: 4473 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4526 Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414 +P A + P E P P T P ++ +AA + P++G Sbjct: 4527 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4585 Query: 415 KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441 E+ +P S K F ++ +P Sbjct: 4586 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4645 Query: 442 KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P A W +G+ + R+ D L ++ + D+G Y+C + + Sbjct: 4646 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4704 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 + L VE L V V ++ ++ V++GQ L C + + W +G+ + Sbjct: 4705 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4758 Query: 559 STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 GV L I DA D GTYT ENA + CS+ V V E Sbjct: 4759 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4805 Score = 100 bits (250), Expect = 1e-20 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%) Query: 1241 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300 ++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L + Sbjct: 14968 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15027 Query: 1301 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360 + G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG Sbjct: 15028 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15087 Query: 1361 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 + + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP + Sbjct: 15088 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15147 Query: 1420 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471 + V P+ PK+ EV D P+ D + IN Y +E R Sbjct: 15148 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15197 Query: 1472 SGKFGQVFRLVEKKT 1486 K GQ + KKT Sbjct: 15198 -DKAGQRWIKCNKKT 15211 Score = 100 bits (249), Expect = 1e-20 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y + Sbjct: 15722 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15781 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 E D++ TW+ + AT T+ L EY+FR+ A N YG S Sbjct: 15782 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15827 Score = 100 bits (248), Expect = 2e-20 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%) Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567 V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623 L I LPED G YT A N G CS + V Y L PV+ + +P Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362 Query: 624 -------------------------------------------------IFLQGLSDLKV 634 +F+ K Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 ++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 +T A N AG +LTV+ +P F+ K ++V G + + G+P P + Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541 Query: 753 HWLRD 757 WL++ Sbjct: 1542 VWLKN 1546 Score = 100 bits (248), Expect = 2e-20 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A++ S +L +V +PL FI P ++ + E AKFE V P+ Sbjct: 5321 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5371 Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114 W + Q IT RF L+ G + + + A +E + + E + SG Sbjct: 5372 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5430 Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144 + VT + F +L + KT F Sbjct: 5431 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5490 Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190 +++ I E P F KL E C+I+ P Sbjct: 5491 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5550 Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248 V W K ++PS + ++L + + D+G YTC G+ K S ++ Sbjct: 5551 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5607 Query: 249 ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287 S++ +++ F ET+ + D+ + I +E K+ S Sbjct: 5608 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5665 Query: 288 LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341 L NC Q GG AAN + K L KD TA +T Sbjct: 5666 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5721 Query: 342 SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395 S L+ +++P + + P E + R + G + Sbjct: 5722 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5771 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 +K + + +F + Q V+E T CEVS +V WF GT + Sbjct: 5772 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 5828 Query: 456 RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515 + + E+ D L + D TY+C A + + SC+ L V+ Sbjct: 5829 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 5878 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572 F L D V E + +C + ++ W +G I+ + + V L I Sbjct: 5879 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632 L +D Y+C A S +TV E+++ +F + L+++ Sbjct: 5938 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 5975 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692 +V + + + +VS P EVIW EI E+ + G + L IQ ED G Sbjct: 5976 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6034 Query: 693 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752 Y C +S RT + V E FISKP+++ G+ C+I+ + FP V Sbjct: 6035 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6085 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796 W RD K L + ++V+ + LV+K G Y +++ Sbjct: 6086 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6128 Score = 100 bits (248), Expect = 2e-20 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%) Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288 MPP I E +V G +V + K+ G T TW K ++ + H+ Sbjct: 9619 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9677 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348 ++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + + Sbjct: 9678 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9737 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407 TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A Sbjct: 9738 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9797 Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 N YG EP + +PE ++ V + D V ++T+N E+ D Sbjct: 9798 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9846 Score = 99.8 bits (247), Expect = 2e-20 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%) Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343 E + +K PQR S P +P P E+ +++ ++KT+ Sbjct: 693 ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750 Query: 344 SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403 T + V PR SP K P G + ++ +A + Sbjct: 751 LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796 Query: 404 PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463 E S+ K ++ VK ++T R P P+ F + + E +EV Sbjct: 797 QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852 Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523 ++ G + + R+ A+ + VE + P+ S LK+ Sbjct: 853 KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580 VIEG+ L+C + G P P +TW I+ + + T ++G+A L I++A ED G Sbjct: 907 TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966 Query: 581 YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614 +TC A N G VS S ++ V EK+++ +E Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026 Query: 615 -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671 P +P AP F+ K+++G V QV GNP P V W +G + + + Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 ++ + L I F +D G YT N GE A L + ++ Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132 Score = 99.4 bits (246), Expect = 3e-20 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++ Sbjct: 17126 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351 + L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+ Sbjct: 17183 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17242 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410 W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y Sbjct: 17243 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17302 Query: 1411 GTSEPSQES 1419 G EP + + Sbjct: 17303 GVGEPLESA 17311 Score = 97.8 bits (242), Expect = 9e-20 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%) Query: 426 KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +E VK+ C++ + +V W+ + E YED G L + D GT Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25141 Query: 485 YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522 Y C N G+ S C T++ + + ++E P F+ L + Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25201 Query: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576 G++ ++ P P +TW +GQ I+ + + G+ +L I + Sbjct: 25202 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25261 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 D YT +A N G+ SC A +TV L P P+F + L++ + + Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25311 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695 G V ++VSG PPP + W +G + + G ++L I++ PEDTG Y Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371 Query: 696 EAWNSAGEVRTQAVLTVQ 713 A N+AG QA L V+ Sbjct: 25372 TATNTAGSTSCQAHLQVE 25389 Score = 97.4 bits (241), Expect = 1e-19 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y Sbjct: 21078 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21137 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T++++N + + + + P P G +I++ S+ LSW +GG + YSI Sbjct: 21138 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21197 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P Sbjct: 21198 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21245 Score = 97.4 bits (241), Expect = 1e-19 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278 + DD G Y + N G+AS A L + G D + R + V E+T Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 25996 Query: 279 --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336 +S K +EA++ + S + + S + ++++S ++ + Sbjct: 25997 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26053 Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396 +K +++ AAR+ +PR+ + GE + PT L V+S Sbjct: 26054 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26105 Query: 397 KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450 +A ++ + + + S S E V EN K E + I K V Sbjct: 26106 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26163 Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509 +P R + V +K+ R S S + + + + T +V+ L V Sbjct: 26164 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563 P + LK A + L C V + + +TW +G+ ++ + Sbjct: 26218 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274 Query: 564 GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609 G EL I + D G Y C G Q A+ ++HEK KS +K+ Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334 Query: 610 EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 ++P AP + + GL D V S V+ +G P P IW +G Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 I + + + L I + D+G YTC NSAG V + LT++ D Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449 Score = 96.7 bits (239), Expect = 2e-19 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y + Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 12928 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 + +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P Sbjct: 12929 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 12976 Score = 96.7 bits (239), Expect = 2e-19 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%) Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64 K + I+KTS + + R + E AF + I EG + + G + V Sbjct: 26521 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26571 Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 W NG +T+ + G+ G+ +L I D G TC + G + +LT+ Sbjct: 26572 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629 Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183 SK L D APA ++P + EGQ F+C+ Sbjct: 26630 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26659 Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243 I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S Sbjct: 26660 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26719 Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301 +A L + L V + V+ + S SL+ +++S S+ + Sbjct: 26720 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26762 Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361 + S ++S E K S ++ Q ++ +SSS + Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26807 Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421 G+ + + E S + KA R IP PK E+ P Sbjct: 26808 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26839 Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480 + E + + C +G P PEV W G + QE G + L ++ + + Sbjct: 26840 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 26899 Query: 481 DSGTYSCTASNAQGQLSCSWTLQVERL 507 D G Y+ + N G S + + + + Sbjct: 26900 DGGLYTLSLGNEFGSDSATVNIHIRSI 26926 Score = 96.3 bits (238), Expect = 3e-19 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%) Query: 1228 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P T PP + + F + +R GE+ L G+ +G +W K + E + + Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346 + + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++ Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405 + +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+ Sbjct: 10431 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490 Query: 1406 AINVYGTSEPSQESELTT-----VGEKPEEP 1431 A N+YG S+P + V + P++P Sbjct: 10491 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10521 Score = 95.9 bits (237), Expect = 3e-19 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%) Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +G + + + K P P I D V GE + + T +W K Sbjct: 7869 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 7985 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392 ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+ Sbjct: 7986 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8044 Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449 DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + + Sbjct: 8045 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8103 Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474 + + K+ + I E++ G+ Sbjct: 8104 KPPLYDGGSKIMGY--IIEKIAKGE 8126 Score = 95.9 bits (237), Expect = 3e-19 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%) Query: 506 RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561 ++A +E+ P ++ EG C + ++TW + ++ + T Sbjct: 25064 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25122 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608 E GVA L+++D D GTY C N G+ S A + V KK R+ Sbjct: 25123 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25182 Query: 609 SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667 ++ + L P + T P++ + G V V ++ +P P V W +G +I+ + Sbjct: 25183 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25237 Query: 668 D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720 + + FE + L I V +D YT A N GE +A LTV P D T + Sbjct: 25238 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25297 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F + GQSV ++G P PT+ W +DG+ L + + D + L Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 ++ P G Y + N G SCQ L ++ Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389 Score = 95.5 bits (236), Expect = 4e-19 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%) Query: 1249 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 ++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G Sbjct: 13893 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 13952 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367 YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY Sbjct: 13953 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14011 Query: 1368 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q + Sbjct: 14012 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14068 Query: 1424 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 V P P ++ EVS+ V T T++ ++ V D Sbjct: 14069 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14101 Score = 94.7 bits (234), Expect = 7e-19 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S+ +F + G TW K I +EN+E+ + L I + G + Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14348 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y + Sbjct: 14349 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14407 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E Sbjct: 14408 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14467 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478 P P D + + D + + + + K++ + +R GS ++ + Sbjct: 14468 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14517 Score = 94.7 bits (234), Expect = 7e-19 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++ Sbjct: 19289 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19345 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L Sbjct: 19346 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19405 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19465 Query: 1410 YGTSEP 1415 YG EP Sbjct: 19466 YGVGEP 19471 Score = 94.4 bits (233), Expect = 1e-18 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23018 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y + Sbjct: 23019 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23077 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E Sbjct: 23078 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23137 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P P ++EV D V TVT+ E+ + D Sbjct: 23138 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23164 Score = 94.0 bits (232), Expect = 1e-18 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y + Sbjct: 18969 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19027 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E Sbjct: 19028 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19085 Query: 1428 PEEP 1431 P P Sbjct: 19086 PFSP 19089 Score = 93.2 bits (230), Expect = 2e-18 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%) Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301 +AG + + + G +W K +K +++ H ++E +EN S + I + Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + H G Y++ +NK G + A + V+D P PP SDI S LSW DGG Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9444 Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 ++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + + Sbjct: 9445 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9504 Query: 1421 LTTVGEK--PEEPKDEVEV 1437 TT + P +P ++++ Sbjct: 9505 RTTARDPIYPPDPPIKLKI 9523 Score = 92.4 bits (228), Expect = 4e-18 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 + P F +L +K A FE R+ G P V W +G+P+ + R + G Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146 SL + D G TC ATN G + L V E S ++ P K L Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773 Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199 + ++ G + P V V EG+ RF C++TG PQP+V W Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 ++ S R V +G+ L+I D G N G +L IQ + RS Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891 Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318 +R + + E K+D ++K +R + Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951 Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378 SK + + T V K+ ++ + EE+K A Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 T PT +P +I + ++ PK + QSQ V + FR V Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 G P PE W+ G + R + + + L + DS + A N G+ S Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557 L V+ ++ +F+ L+D E P ++ W +G + Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172 Query: 558 --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 R + V L I D Y+C V V ++ ++ ++ Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218 Query: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672 A + F++ L D++V + + VS PE I W HN E++ + + Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269 Query: 673 QRGTQHSLCIQEVFPEDTGTYT 694 R + +L +++V ED G Y+ Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291 Score = 92.4 bits (228), Expect = 4e-18 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%) Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290 P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++ Sbjct: 18208 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18264 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + L + + G Y L + N G++ + + V+D+P PP G + + + L Sbjct: 18265 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18324 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N Sbjct: 18325 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18384 Query: 1410 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438 YG EP + +T KP P EVS Sbjct: 18385 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18414 Score = 92.4 bits (228), Expect = 4e-18 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 T + TV+ T + MP + I P AG VEL + G P +W Sbjct: 23226 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23279 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 +++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP Sbjct: 23280 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23339 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394 G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L Sbjct: 23340 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23399 Query: 1395 LPDHEYKFRVRAINVYG 1411 +EY FRV A N +G Sbjct: 23400 TEGNEYVFRVAATNRFG 23416 Score = 92.0 bits (227), Expect = 5e-18 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%) Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 +P+T P + +N+ + EG + E + GYP P VTW+R I S F + Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143 G L+I ED G++TC A N +G + L V+ S + V++ T R Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009 Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194 F S V T S+ E P F TK + EG F C++ G P+P V W Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069 Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 K VPL R VS +++ G L I DD G YT +V N G+ S SA L Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125 Score = 92.0 bits (227), Expect = 5e-18 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AGE V++ G P T TW K K + +EN+++ S LTI + G Y Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20846 Query: 1310 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I Sbjct: 20847 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 20965 Query: 1428 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474 P P ++ + D + + + + ++++ + ER G G+ Sbjct: 20966 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21009 Score = 91.7 bits (226), Expect = 6e-18 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y + Sbjct: 16804 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16863 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 + D+ W + AT T+ V L EY+FR+ A N YG S Sbjct: 16864 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909 Score = 91.3 bits (225), Expect = 8e-18 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%) Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301 KV+AGE V + VTG W K I++ +V SE ++L+I A Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 +E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9030 Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418 + Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ + Sbjct: 9031 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9090 Query: 1419 SEL 1421 ++ Sbjct: 9091 DKV 9093 Score = 91.3 bits (225), Expect = 8e-18 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%) Query: 1226 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282 P P PP++I +Q ++ G+++ L + G TW K + Sbjct: 10707 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10766 Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342 + V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+ Sbjct: 10767 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10823 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401 IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y Sbjct: 10824 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 10883 Query: 1402 FRVRAINVYG 1411 FRV A N YG Sbjct: 10884 FRVAAENQYG 10893 Score = 91.3 bits (225), Expect = 8e-18 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%) Query: 1232 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PKA +PP+I + +KV RA ++ LF + G W R + + Sbjct: 15352 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15409 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 +E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++ Sbjct: 15410 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15468 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV Sbjct: 15469 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15528 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A N YG P++ +E E+P P Sbjct: 15529 LAENEYGIGLPAETAESVKASERPLPP 15555 Score = 90.5 bits (223), Expect = 1e-17 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%) Query: 1249 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307 V AG + + V+G P T TW M R QE+ +E + S + I ++ H G Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10095 Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10154 Query: 1367 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425 IE +S + W + T + VQ L+ Y FR+ A N G + SE + Sbjct: 10155 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214 Query: 1426 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475 E PE P+D +EV EV TVT+ D Y +E RL G+ KF Sbjct: 10215 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10266 Query: 1476 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524 K T + + KE + +S +N + K C Sbjct: 10267 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10308 Score = 90.1 bits (222), Expect = 2e-17 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 +RAG S+ LF + G W K +I+++ + V +S + L + + G Y Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16514 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y + Sbjct: 16515 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16573 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E Sbjct: 16574 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16633 Query: 1428 PEEP 1431 P+ P Sbjct: 16634 PQPP 16637 Score = 90.1 bits (222), Expect = 2e-17 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%) Query: 1228 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278 P P +++++P+ D++ + G V G + T PI C W K + I Sbjct: 23621 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23680 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G Sbjct: 23681 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23738 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397 DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L + Sbjct: 23739 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23798 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454 EY FRV A N +G S+P + E T PE P + EV D + + + Sbjct: 23799 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23858 Query: 1455 NTEQKVSDFY 1464 + +V+ +Y Sbjct: 23859 DGGSRVTGYY 23868 Score = 89.4 bits (220), Expect = 3e-17 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679 AP F Q L + V++GS T +SG P PEV W +G I S + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122 Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799 + + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 800 VGECSCQVSLMLQ 812 VG + L++Q Sbjct: 182 VGRATSTAELLVQ 194 Score = 89.0 bits (219), Expect = 4e-17 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%) Query: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467 Q++ P P+ V E +T +FRC V+G P+P+V W+L G +R+ + Y+ Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846 Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527 G HYL ++ ++ D+G TA N +G + L++++ F SVL+ Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900 Query: 528 GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V LQ V+ P + L + I + + E+ EL + Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958 Query: 576 EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618 + G Y + E L + W E+K + E + + Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018 Query: 619 KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 KP AP + + V GS V+V G P PE W NG +I+ S+ Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078 Query: 670 H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728 + + L I++V ED+ + +A N AGE + A L VQ T F + + Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135 Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758 V A ++ +PF V W +DG Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165 Score = 87.8 bits (216), Expect = 9e-17 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%) Query: 1232 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285 PK + P I + VRAG + LF V G TW K +++ + Sbjct: 12100 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12156 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+ Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12215 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404 +S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV Sbjct: 12216 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12275 Query: 1405 RAINVYGTSEPSQESELTTVGEKPEEP 1431 A+N YG P+ + + EP Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEP 12302 Score = 87.8 bits (216), Expect = 9e-17 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%) Query: 1228 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 P P P I+ PE + +RAG ++ L+ V G P TW K + Sbjct: 13178 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13237 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 ++ + +++++ + L + G Y L +EN G ++ + + V+D P PP Sbjct: 13238 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13296 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397 +I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L Sbjct: 13297 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13356 Query: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428 Y FRV A N YG +P + + + P Sbjct: 13357 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13387 Score = 87.8 bits (216), Expect = 9e-17 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%) Query: 1237 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I + +KV RA ++ LF + G W K + ++ ++E + + + Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18664 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18723 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG Sbjct: 18724 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783 Query: 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 P++ +E V E P P V +V T TI E+ SD Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18825 Score = 87.0 bits (214), Expect = 2e-16 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VRAG S + G TW R++ + ++ +++E N ++L+I + G Y Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17596 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I Sbjct: 17597 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17655 Query: 1369 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 + +S K + +++ C TSF V++L Y FRV A N +G P + + E Sbjct: 17656 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17715 Query: 1428 PEEP 1431 P P Sbjct: 17716 PSPP 17719 Score = 87.0 bits (214), Expect = 2e-16 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 ++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y + Sbjct: 17886 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 17945 Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 E D+ TW + AT T+ + L EY+FR+ A N YG S P Sbjct: 17946 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 17993 Score = 85.9 bits (211), Expect = 3e-16 Identities = 67/238 (28%), Positives = 104/238 (43%), Gaps = 21/238 (8%) Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG- 77 V P++ DS P FI N I G A V G P+P++ W NG +T Sbjct: 3443 VYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD 3502 Query: 78 -RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVV 136 +F+ D SL+I ED G+YTC A+N G T+ ++ K + Sbjct: 3503 YKFVFD---GDDHSLIILFTKLEDEGEYTCMASNDYGK-------TICSAYLK-----IN 3547 Query: 137 SKTLGDRFS---APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT 193 SK G + + + ++ + G CPP F +L + +G F + G P P VT Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607 Query: 194 WLKGNVPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 W K N L S + + NG ++ ++D G+Y C N G+++ +AEL + Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665 Score = 85.5 bits (210), Expect = 5e-16 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472 P F QS V E T F +SG P PEV+WF +G + +++ G L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531 + +SG YS A+N GQ T E L E A P+F L+ V +G Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 LQ V G P P + + +G IQ + + + E + L I +A PED GTY+ A N+ Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181 Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616 +G+ + +A + V E+ ++K++ ++ A Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211 Score = 85.5 bits (210), Expect = 5e-16 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+ Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I D G++T A N +G ++V LTVE AVE Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505 Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210 + P F KL V +KEG + TG P P + WLK + + P ++ + Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561 Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 G L+I D YT +N +G+ + +++++ Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602 Score = 84.0 bits (206), Expect = 1e-15 Identities = 65/256 (25%), Positives = 111/256 (43%), Gaps = 35/256 (13%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ VA + S +L V+ E P + + + ++ G A+F + G P+ Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221 Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P+++W++ Q +++G + FL D ++L++ ED YTCEA N G + Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278 Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179 L+VE P V + PP T L V EGQ R Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317 Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239 F C+++G +V+W + ++PS +++ LEI +D G YT + N Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376 Query: 240 GKASMSAELSIQGLDS 255 G+ S +A LS++ +S Sbjct: 3377 GQVSSTANLSLEAPES 3392 Score = 84.0 bits (206), Expect = 1e-15 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%) Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320 + G + +W K + + VE+S + L + ++ G YT+ ++N G+++ Sbjct: 13509 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568 Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 +++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W Sbjct: 13569 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13628 Query: 1381 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414 A+ + T+F V L EY FRV A N YG E Sbjct: 13629 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13663 Score = 83.6 bits (205), Expect = 2e-15 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%) Query: 1237 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 PP+I FP VRAG ++++ ++G T + ++ + E + Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20035 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 + + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W Sbjct: 20036 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20095 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G Sbjct: 20096 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20155 Query: 1413 SE 1414 S+ Sbjct: 20156 SD 20157 Score = 83.2 bits (204), Expect = 2e-15 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%) Query: 1238 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293 P I++F + +++GES+ + V G TW K +I++ +M++ + + Sbjct: 21458 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21517 Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353 L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W Sbjct: 21518 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21577 Query: 1354 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412 DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G Sbjct: 21578 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21637 Query: 1413 SEP 1415 P Sbjct: 21638 GRP 21640 Score = 82.8 bits (203), Expect = 3e-15 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%) Query: 882 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938 H EE+ QQ + +++ ++S ++E + PA + + + VKP+ + Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726 Query: 939 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997 SE K + + S + K T V P+ A+P F K +P Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783 Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055 A + K LS + + + + A T+KP AE L A Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840 Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095 + KS + E+KK+V + GTT E+R E Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894 Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155 T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + + Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213 I +A ED G + C A N+AG SC V V + E T E + K + Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 +D ++ ++ A P A P I P QK+ G SV +V G W K Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071 Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325 + KV N + G KL I + G YT++V NK G A +L Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125 Score = 82.4 bits (202), Expect = 4e-15 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%) Query: 405 MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457 ++G++ + K + +P Q+V E V+ +VS + E W +G V+ Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352 Query: 458 EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517 + + + D SH L + D+G YS T L S + +V +V + P Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404 Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574 LKD VIEG VL+C V V + W LN + I+ ++ + L I Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462 Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634 D G Y + +G+V + ++V + K ++GL DL Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498 Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694 + V V++S + +V+W EI+ S + E G + L + + +D G YT Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557 Query: 695 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753 AGE T LTV ISKP T + Q + C +A +P Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605 Query: 754 WLRDGKAL 761 WLRDGK L Sbjct: 2606 WLRDGKHL 2613 Score = 82.4 bits (202), Expect = 4e-15 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%) Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144 D E R++ + AP K QD+ V GK L + + P A W + L T Sbjct: 6490 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6549 Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204 +++ S + +K D+G YK V +N G+AE + V D P Sbjct: 6550 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6594 Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264 PV E T + + ++ + G S ++ G V Sbjct: 6595 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6631 Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322 + I TW+ + + E + G + + + G + +N + +R Sbjct: 6632 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6691 Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W Sbjct: 6692 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6744 Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 T R+ S V D++ EY FRVRA N G +PS + V + E P V ++ Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6804 Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493 D+ + V + + I ER GK + +LV + T KV K Sbjct: 6805 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6864 Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516 + SA+ K + I+ L Sbjct: 6865 YLYRVSAENKAGVSDPSEILGPL 6887 Score = 82.4 bits (202), Expect = 4e-15 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 V+AG S + G W K ++ + V+ +++ + LTI A + G Y Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19758 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I Sbjct: 19759 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19817 Query: 1369 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 E +++ K W + C S+ V +L Y FRV N +G P++ E + EK Sbjct: 19818 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 19877 Query: 1428 PEEPK 1432 P P+ Sbjct: 19878 PSPPE 19882 Score = 82.4 bits (202), Expect = 4e-15 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%) Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G Sbjct: 24410 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24469 Query: 662 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 EI + + ++ +G H L I V +D Y A N G V A L V+ P Sbjct: 24470 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24529 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L Sbjct: 24530 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24588 Query: 780 VLKK-VQPWHAGQYEILLKNRVG 801 V V+ AG Y + KNR G Sbjct: 24589 VFPNGVERKDAGFYVVCAKNRFG 24611 Score = 82.0 bits (201), Expect = 5e-15 Identities = 87/338 (25%), Positives = 138/338 (40%), Gaps = 26/338 (7%) Query: 384 TRQPGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP 441 TR G VV+ + ++ +EG RD + + Q E K+ V+F + Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAKLFVEG-RDVRIRSIKKEVQVIE-KQRAVVEFEVNEDDV- 3129 Query: 442 KPEVAWFLEGTPVRRQEGSIEVYE-DAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 + W+ +G + Q Y + H + + + R D+G Y+ A G+ S Sbjct: 3130 --DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSV 3183 Query: 501 TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--- 557 TL V P L+ V G+ + G P P+I+W Q + Sbjct: 3184 TLYVNA----PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 + + L + +A PED YTC A+N G + SA ++V E + +PV P Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMPVYP 3298 Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677 P + L D +G +VSG +V W +I+ S F Q Sbjct: 3299 -----PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDT 3352 Query: 678 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 + L I E +PED GTYT A N+ G+V + A L+++ P Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3390 Score = 82.0 bits (201), Expect = 5e-15 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%) Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78 R D+M L E P F LP N G +F + +PEP VTW+++GQ I G + Sbjct: 25182 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25241 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + + +G + L I++V +D +YT A N G +LTV L P Sbjct: 25242 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25294 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 TL P F L +EGQ F +++G P P + W K Sbjct: 25295 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335 Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257 PL + + E L I +D G Y N +G S A L ++ L Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395 Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290 + F + + V+K++ + L E+ Sbjct: 25396 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25427 Score = 81.6 bits (200), Expect = 7e-15 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306 V+AG+++ L V G W K + + S +K++ + SK ++ A++ G Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775 Query: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y Sbjct: 11776 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11834 Query: 1367 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423 +E ++ W AT + V L+ +EY FRVRA N GT P++ + T Sbjct: 11835 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 11894 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464 +KP P D EV+ ++E V + + + ++ ++ Sbjct: 11895 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 11934 Score = 81.6 bits (200), Expect = 7e-15 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 + ED G YTC A N GEV T + L +Q P + K + A +G ++ + Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24152 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800 G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N Sbjct: 24153 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211 Query: 801 GECSCQVSLMLQN 813 G + + +Q+ Sbjct: 24212 GTVDAILDVEIQD 24224 Score = 81.3 bits (199), Expect = 9e-15 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%) Query: 416 FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474 F + Q KE T+ F CE S P +V W+ +G V + ++ D H+L + Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187 Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 L T D+ YSC + + + +L V F L+D V E L+ Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241 Query: 535 CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 C V + W N ++ T G L ++D ED G Y+ + + Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 KK++ K + KP LQGLSD KV +G V + V+VS Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338 Query: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707 E +W+ +G E+Q S+ H H L I+++ ED G Y+ +++G V Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397 Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 +V I+ + V G ++ C ++ +V W + + + K Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444 Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 + + LV+ + G Y++++ RV E +C +S+ Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484 Score = 80.9 bits (198), Expect = 1e-14 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 + E ++ F E+S P W L+G + R + E+ + G +L L K + +G Sbjct: 4911 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 4968 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 A NA + L V E+ F+ LKD V E + +C + T Sbjct: 4969 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5017 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601 + W I+ + + HI D+ +D G YT E + S +VT Sbjct: 5018 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5075 Query: 602 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661 K F+ L D V +G T ++S + V+W N Sbjct: 5076 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5114 Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721 ++ S G H L ++EV +D + E+ + A L V E P Sbjct: 5115 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5166 Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781 +F K TA + + C ++ D V W +DG+ + + + + L + Sbjct: 5167 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5223 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837 KK G+Y C C N + A L + +P ++ G Sbjct: 5224 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5274 Query: 838 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889 + D +G W +GQ D E + K + T + + +A Sbjct: 5275 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5330 Query: 890 QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949 + L ++L + LS D+K ++ F + R+ PKT R + Q Sbjct: 5331 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5380 Query: 950 QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007 ++ D R L K GT + V + A F + + +G E + K Sbjct: 5381 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5434 Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067 + K ++ + + V + +K N + T + + + + + S + ++L Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5493 Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127 D + + + G + K + +G P F KLQD E +++LQC++S A Sbjct: 5494 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5549 Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + W +GK +K +K ++ +G + ++KAL D G Y C D G + S ++ + Sbjct: 5550 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5605 Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 +D E+K RP S+ V+ TE+ Sbjct: 5606 EDR---------EIKLVRPLHSV-EVMETET 5626 Score = 80.9 bits (198), Expect = 1e-14 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%) Query: 1231 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 PPKA + ++ + +RAG + L V G W K K++ E + ++ + Sbjct: 22546 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603 Query: 1291 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350 + I + G YTL V+N G++ V + V+D P P G S + TL Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22662 Query: 1351 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 +W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N Sbjct: 22663 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22722 Query: 1410 YG-----TSEPSQESELTTVGEKPEEPKD 1433 YG SEP T+ P P++ Sbjct: 22723 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22751 Score = 79.7 bits (195), Expect = 2e-14 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%) Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 +AG+++++ V G T TW K + +++++ + E + + L I + G Y Sbjct: 14581 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14640 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 L N +G + + V D P PP G ++ S +T SW DGG + +Y +E Sbjct: 14641 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14700 Query: 1370 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411 + + + TW ELA T T++ L EY+FRV+A N YG Sbjct: 14701 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743 Score = 79.3 bits (194), Expect = 3e-14 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Query: 1789 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848 EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD + Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284 Query: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336 Score = 79.3 bits (194), Expect = 3e-14 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%) Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80 P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079 Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140 LVI V ED +A N +G L V+ AKQL Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127 Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199 F +L VV KE M F C+ T P +V W K + Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166 Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 + + + + L I ++ D Y+C++V +A+L ++G A Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222 Query: 260 FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312 FV+E + E+ ++S E+ + +E + K + +RG + Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282 Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363 + E K +CK + P +LQ S + VQ E + GV Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341 Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420 G+E +P+ + L +D+ + A IP G S S Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400 Query: 421 QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 +K+ ++ C+VS V W+L + + + ++ L + Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 + D G Y G++ + L VE++ ++ L+D E Q+ V + Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508 Query: 536 SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592 + + + + W + I+ + + + +L + + + +D G YT A G+ Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563 Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652 S +TV A SKP L+D V + + +V+ NP Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602 Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + WL +G + + + E G + L I +D G YT + S +T A L V Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658 Query: 713 QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 + I K +++T + Q + + + V W+++G L Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701 Score = 79.0 bits (193), Expect = 4e-14 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471 P+F ++ + V+F ++ P+P V W+ G ++ + + D G + Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528 L + T D Y+ A N G+ SC L V + P F +L + EG Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25312 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584 Q + V G P P + W +GQP+ + G+ LHI+D LPED G Y Sbjct: 25313 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25372 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEY 611 A N G SC A + V E+ +K E+ Sbjct: 25373 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25398 Score = 78.6 bits (192), Expect = 6e-14 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%) Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276 +P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K Sbjct: 8167 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224 Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310 ++QE E + ++NS+ G S+L + + + G Y + Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284 Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370 VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8343 Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427 D + W + +T R ++V L+ EY FRVRA N +G P L V + Sbjct: 8344 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8401 Query: 1428 PEEPKD 1433 P P D Sbjct: 8402 PFGPPD 8407 Score = 78.2 bits (191), Expect = 7e-14 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%) Query: 36 ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94 I P +++ + EG A E +V V W+ N + I R + ++GT LVI+ Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459 Query: 95 AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154 H D G Y G + L+VE Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487 Query: 155 IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214 K L + E Q F +++ V W + ++PS++ + Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272 + L + + +DD G YT +G+ S +L++ G + ++ +T A + + Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594 Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329 EV N SK L + + N S G A K+ + K S Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654 Query: 330 RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378 + + ++KT ++T+ + P G+ GV+ S E+ Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714 Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438 + + + + V R + + K KP+ EN TV F VS Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773 Query: 439 GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498 P V WF + ++ + + + H L L D+G Y+ GQL C Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827 Query: 499 SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558 L VE L + + +K+ V E + +C V VP + WL NG I+ + Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879 Query: 559 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615 + + +L I + ED YT + N QVS + VT Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921 Query: 616 APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674 PI + L D+ + +T V V+ WL NG EI+ ++ + Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973 Query: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 HSL I+ V D YT AG+ + A L V+ H F + + Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 + + C ++ +P TV W++D + L + T ++ + + V L++ + AG+Y + Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083 Query: 795 LLKNRV 800 + V Sbjct: 3084 VAGGNV 3089 Score = 78.2 bits (191), Expect = 7e-14 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%) Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 P T A + P + F + +V + + TG T TW K ++ + +K Sbjct: 6886 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 6945 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345 ++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI Sbjct: 6946 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7004 Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404 S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V Sbjct: 7005 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7064 Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433 A N G EP+ E ++T P+ P++ Sbjct: 7065 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7096 Score = 78.2 bits (191), Expect = 7e-14 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA ++L V ++ +L + D + I L K + F + + + ++ Sbjct: 22049 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22108 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 E+ + + ++ AKNDAG +E P+ + V+ Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22140 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 +K+ T + Q+I +AG + ++G TW + Sbjct: 22141 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22190 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337 ++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G Sbjct: 22191 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22250 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396 S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L Sbjct: 22251 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 EY FRV + N +G S+P + + + + E P P Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22343 Score = 77.4 bits (189), Expect = 1e-13 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%) Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 S+DVV + G + A P F +KP Q++ E +V F C+V G PKP V W Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072 Query: 451 GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509 G P+ + + G L + D+G Y+ N G+ S S +L +E Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567 + S +L V FV + V G P + + + ++ +A+ Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625 + ++ + + + E + ++ T E+ + + + + ++ S+ F Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247 Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683 + + ++++G VT ++SG P P++ W +G I+ E + F Q G + SL I Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306 Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732 V PED G YT A N G L V+ P +I PRSV+ Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366 Query: 733 S 733 S Sbjct: 1367 S 1367 Score = 77.0 bits (188), Expect = 2e-13 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16792 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y N GQ S ++ D P + K P Sbjct: 16793 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16835 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 D + + PP QI + ++ T W Sbjct: 16836 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 16879 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332 + + +KV + G++ + + EN+ G A + +V +P Sbjct: 16880 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 16927 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385 PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT Sbjct: 16928 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 16981 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 T F Q+L EY+FRV A N+ G + S+ SE + + P Sbjct: 16982 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17027 Score = 76.6 bits (187), Expect = 2e-13 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+ Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206 +D Y C ++ +A + + V+ +AP ++ E+ + Sbjct: 6387 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6446 Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241 ++++ V G + + K + + A P+I Sbjct: 6447 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6506 Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301 +D V G+ + + W K + + ++ + + IL A+ Sbjct: 6507 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6563 Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361 + G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS Sbjct: 6564 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6622 Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418 + Y +E D KTW LAT R+ S F V L EY FRV A N GT EP + Sbjct: 6623 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6681 Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441 K + P + V+ D Sbjct: 6682 DNPVEARSKYDVPGPPLNVTITD 6704 Score = 76.3 bits (186), Expect = 3e-13 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%) Query: 1772 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1830 S TG+ E L E V++ E P P ++++ V+EG + +C Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918 Query: 1831 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977 Query: 1891 ATCTAELIVETMEEGEGE 1908 + + L V+ EE E E Sbjct: 978 VSTSCYLAVQVSEEFEKE 995 Score = 75.9 bits (185), Expect = 4e-13 Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678 K P+ L D +G V +T ++ EV W + E F Q + Sbjct: 4239 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4296 Query: 679 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737 +L I +V ED G Y CEA N +G+ T A LTV + P K + +LG Sbjct: 4297 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4353 Query: 738 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797 +C I P W + G+ + ++ + ++ + +L + + Q G+Y Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4412 Query: 798 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 N G SC +L + R L R+P E++ S+ Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4459 Query: 854 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913 P + +E + E V K+ + + + EV + R+ +K+ T + Sbjct: 4460 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4512 Query: 914 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970 IP + + + +V KP V E + +P V V+ KK +K P E Sbjct: 4513 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4569 Query: 971 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027 P P + G KK P+ + + E P + + PLK V Sbjct: 4570 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4622 Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073 K + +G++ E L A K N++ + K D K+ Sbjct: 4623 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4682 Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124 + C + G+ T K + K ++V V +G+ L L C+++ + Sbjct: 4683 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4742 Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183 ++W +GK ++ I+ G + +++I A D G Y +N A ECS Sbjct: 4743 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4799 Query: 1184 QVTV 1187 V V Sbjct: 4800 CVKV 4803 Score = 75.9 bits (185), Expect = 4e-13 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%) Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105 N++P ++LK +E + D + + + +A G ++ + SE+ P + Sbjct: 7838 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 7897 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165 D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 7957 Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225 G+Y +N G A S V V P ++K+ SD T Sbjct: 7958 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 7999 Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285 PP+ G PI ++ R++ ++ Sbjct: 8000 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8031 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343 V + EN T+ + + NK+G + N + P P P ++ Sbjct: 8032 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8091 Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395 + ++T++W YDGGS + Y IE + WK C ++ + L Sbjct: 8092 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8148 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442 EY+FRVRA N G SEPS+ + T + + PK +EV DE Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8199 Score = 73.9 bits (180), Expect = 1e-12 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VKE Q V F CEV+ + WF + I + +D + L + A D Sbjct: 6154 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6211 Query: 485 YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 Y+ + +N +G+ + + L VE + V P LKD +E + C V V Sbjct: 6212 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6266 Query: 544 RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W NG+ + + H I+D D G Y VT Sbjct: 6267 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6310 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 + KS +E L+ AP++ F++ L D V + + Q+S V W NG Sbjct: 6311 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6362 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719 EI+E + + FE+ G+ H L I++ +D Y C + +++A L V+E P + Sbjct: 6363 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6418 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 +P P+ + + G V+ + D V WLR+ + + H +++ + L Sbjct: 6419 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6471 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVS 808 + ++P G+Y + K++ +++ Sbjct: 6472 QICDIKPRDQGEYRFIAKDKEARAKLELA 6500 Score = 73.9 bits (180), Expect = 1e-12 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V+V G L + +S P + + +G LK T ++++++++ D G Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224 Y+ A N +G + + V D P P V+ TE T+K Sbjct: 20049 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20094 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P PK + + I+ ++ S ++ +V+ T + T MK K E+ Sbjct: 20095 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20144 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344 +EN + + + S V L P PP+ TP +++ Sbjct: 20145 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20185 Query: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402 S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F Sbjct: 20186 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20245 Query: 1403 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462 RV A N G +PS SE + E P++ V ++D + + ++ + K++ Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20304 Query: 1463 FYDIEER 1469 Y +E R Sbjct: 20305 -YIVERR 20310 Score = 73.6 bits (179), Expect = 2e-12 Identities = 33/91 (36%), Positives = 56/91 (61%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++D +D Y CKA N LGE+TC AEL+V Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665 Score = 73.2 bits (178), Expect = 2e-12 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328 R+++ ++ +++ G+ L + ++ + + EN+ G S + T + Sbjct: 23770 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23829 Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386 + P+PP+ P D+ SS++LSW DGGS V Y IE +++ W + Sbjct: 23830 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 23889 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437 T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+ Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 23942 Score = 72.4 bits (176), Expect = 4e-12 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%) Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++ Sbjct: 8601 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8656 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347 N S+L I A ++ G Y + N GS+ A + V D P P R Sbjct: 8657 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8716 Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407 L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A Sbjct: 8717 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8775 Query: 1408 NVYGTSEPSQESELTTV 1424 N +G P + + V Sbjct: 8776 NKFGCGPPVEIGPILAV 8792 Score = 71.6 bits (174), Expect = 7e-12 Identities = 74/293 (25%), Positives = 111/293 (37%), Gaps = 39/293 (13%) Query: 13 SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68 + SLSV+ V S MP+ PA I P ++ EG A+F+ RV G + +V+W+ Sbjct: 3276 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3333 Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE---- 124 + I RF T+ L I + ED G YT A+N G T L++E Sbjct: 3334 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3392 Query: 125 ---------------------------GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157 G + +L +++TL +P T+ Sbjct: 3393 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEK 3452 Query: 158 E-CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216 E P F ++ + G + S + G P+P++ W V L PSA Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3512 Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269 L I +D G YTC+ N GK SA L I ++ E+ S Sbjct: 3513 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 3565 Score = 71.6 bits (174), Expect = 7e-12 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 +D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T Sbjct: 20667 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20725 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+ Sbjct: 20726 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20779 Score = 71.2 bits (173), Expect = 9e-12 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%) Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324 P T W++ K + +V+ N K + +L EN G + + Sbjct: 7427 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7475 Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 + + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W Sbjct: 7476 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7535 Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437 +A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV Sbjct: 7536 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7595 Score = 70.9 bits (172), Expect = 1e-11 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538 Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119 P + W +N I + ++ G +G +L I + +D YT A N +G Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597 Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161 ++ VE FA+ + + G +AP +E +G + P Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657 Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 F KL + +K F C++T G P V WL PL+ + R+ + + G L+ Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 D G+ TC N G SA L ++ +S V E++ Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759 Score = 70.9 bits (172), Expect = 1e-11 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 SE +GT P F +++ + ++ G L V P I W NG L + +G Sbjct: 3450 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3509 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 S+ I ED G Y C+A ND G+ CS + + N+K K Sbjct: 3510 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3555 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 TE+++ V K P PP ++ + + G V G T T Sbjct: 3556 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329 W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+ Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3667 Query: 1330 KPDPPAGTPC 1339 + TPC Sbjct: 3668 EDTDMTDTPC 3677 Score = 70.9 bits (172), Expect = 1e-11 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y + N C++ V P + T P K + P Sbjct: 21136 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21166 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283 I+F E + +SV L V G ITC ++ R+ Q + Sbjct: 21167 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21208 Query: 1284 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337 M + + K+ L E+ + + EN+ G Q V+ +V K P PP G Sbjct: 21209 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21265 Query: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395 P ++ S ++L+W YDGGS V + +E + + W+++ T + L+ Sbjct: 21266 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21325 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455 +Y+FRV A N G S PS S+ T+ P +P + D V T+T+ Sbjct: 21326 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21377 Query: 1456 TEQKVSD------FYDIEERLGSGKF 1475 + D Y IE+R G+ ++ Sbjct: 21378 WNPPLRDGGSKIVGYSIEKRQGNERW 21403 Score = 70.5 bits (171), Expect = 2e-11 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G+V A + I+ L+V +D F +P +++ + E A+FE + E Sbjct: 4967 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5015 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W + I S +F + + LVI+ +D G YT E Sbjct: 5016 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5060 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 VEG K R + KF + L VKEG+ F Sbjct: 5061 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5097 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C+++ + V W K + L S V +S + LE+ V DD+ V + Sbjct: 5098 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5152 Query: 242 ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283 S +A+L + D + + A D V K+V K+ Sbjct: 5153 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5212 Query: 284 KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337 K D L K K +G G+ AN + R K+E P + V Sbjct: 5213 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5267 Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397 + I L V + + G + + E Q G+ + +V + Sbjct: 5268 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5326 Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456 AAN + + P P S +V E KF CEVS PK W L+GT Sbjct: 5327 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5383 Query: 457 QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516 + E+ +D H + + A D Y A + +L + + F Sbjct: 5384 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5434 Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576 + LKD E + V + + R+ W N Q + RS + +QD Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5485 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 T+ L+ + Q+ A SE L V P F L D ++ Sbjct: 5486 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5534 Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 +V + ++S P V W +G EI+ S++ + G + L +++ D G YTC+ Sbjct: 5535 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5593 Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 G +T L +++ + + SV ++ I+ D +W Sbjct: 5594 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5644 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVL 781 G+AL + T E+ + + +LVL Sbjct: 5645 KGEALLQ-TPDCEIKEEGKIHSLVL 5668 Score = 70.5 bits (171), Expect = 2e-11 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L + V G K+ L V+ P I WT LK K I + +V+I + Sbjct: 7200 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7259 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y A N G+A +V V D P PP +D T + Sbjct: 7260 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7301 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 PP+ +I + +++ E W K ++++ Sbjct: 7302 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7345 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339 K T L +E+ + + EN G Q + +T + DPP G P Sbjct: 7346 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7392 Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396 SDI ++TL+W DGGS + Y +E D W + T++ V+ L Sbjct: 7393 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7452 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 +Y+FRV A N+ G +PS+ +E + + + P Sbjct: 7453 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7487 Score = 70.1 bits (170), Expect = 2e-11 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1866 P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 L I V + +Y+ KA N G+AT TAEL+V+ Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98 Score = 69.3 bits (168), Expect = 3e-11 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%) Query: 1217 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271 ESD V + P P TP A+ + + V G S + + + + W Sbjct: 16913 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 16972 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 K K I K +N E G + + + EN +G +A N Sbjct: 16973 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17021 Query: 1332 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387 DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T Sbjct: 17022 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17081 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438 F V L D Y+FRV A N G S+PS + T ++ E P +D + V+ Sbjct: 17082 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17141 Query: 1439 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495 + E D + T + + +IEE F+ L+ K ++ G++ Sbjct: 17142 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17201 Query: 1496 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554 +A + ++ + +++ P+ VQ EK ++ + GG + E Sbjct: 17202 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17261 Query: 1555 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598 E + E + +++ EG EY+ + IM VNK G Sbjct: 17262 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17303 Score = 69.3 bits (168), Expect = 3e-11 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357 GC Y + EN G ++ DP P P D +++T++W + Sbjct: 19553 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19612 Query: 1358 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS Sbjct: 19613 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19672 Query: 1417 QESELTTVGEKPEEPKDEVE 1436 S+ E+ EEP +++ Sbjct: 19673 DSSDPQIAKEREEEPLFDID 19692 Score = 69.3 bits (168), Expect = 3e-11 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%) Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310 E S ++EVT + E + + + A + + S+ + R SP + Sbjct: 25732 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25791 Query: 311 --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368 S+PQP E + ++ + SP TP + PR+P SP Sbjct: 25792 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 25826 Query: 369 EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423 ER R A F +R + + K + R+ + Q+ P+ + +S Sbjct: 25827 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 25886 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 V Q +F V P EV W+ G ++ + I +G L +L T DSG Sbjct: 25887 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 25945 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542 TY +N +G+ S TL V G D+ S R V Sbjct: 25946 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 25983 Query: 543 PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596 PR + + YA S+ EA + ++ + E + + +A ++ +A Sbjct: 25984 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26043 Query: 597 WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654 ++ EK ++RK + L A L + V +G + G P P V Sbjct: 26044 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095 Query: 655 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714 WL G + S + + I V D G Y+ NS G+ + LT+Q+ Sbjct: 26096 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26155 Score = 69.3 bits (168), Expect = 3e-11 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L AP L R+ + G +F V+ P +V W+ NG + + G Sbjct: 25873 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 25931 Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121 +L I H +D G Y T + T G R V EL Sbjct: 25932 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 25991 Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157 T ++A K+ + S ++ + + ETR S+ Sbjct: 25992 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26050 Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207 + TK + V EG+ RFSC G P P VTWL+ L SAR Sbjct: 26051 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26110 Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267 V+ EI V D G Y+ +V N GK L+IQ ++ V E KA Sbjct: 26111 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26163 Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327 S R V S E ++ S EA K SP+ P P + + E + Sbjct: 26164 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26214 Query: 328 SPRTAP 333 P +AP Sbjct: 26215 LPVSAP 26220 Score = 68.9 bits (167), Expect = 4e-11 Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%) Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502 EV W+ E V E + +D ++ L + K T D G Y C A N G+ + S L Sbjct: 4271 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329 Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562 V V AP ++ V G C ++ P R W G+ I Y C Sbjct: 4330 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4384 Query: 563 AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618 ++ L I D G YTC A N G VSC+A +TV +K LLP Sbjct: 4385 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4444 Query: 619 KPTAPIFLQGL 629 +P + L+ + Sbjct: 4445 EPKEEVVLKSV 4455 Score = 68.9 bits (167), Expect = 4e-11 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%) Query: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 P KL V V G + L+ V P + WT + T+ + + Sbjct: 11704 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11763 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213 S+ KA D G Y A N AG V V D P N K ++ S R Sbjct: 11764 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11815 Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 TV P P+ + I++ E +++ W Sbjct: 11816 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11848 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330 + + G+ +T L E+ + + ENK+G+ + V+ K Sbjct: 11849 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 11896 Query: 1331 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 PDPP T + + +T+ W YDGG ++ Y +E + + W + + Sbjct: 11897 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 11952 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 VQ+LLPDHEY+FRV+A N G EPS S V + P EP Sbjct: 11953 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 11999 Score = 68.6 bits (166), Expect = 6e-11 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 18957 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++A ED G Y+ N AG + V D P PP Sbjct: 18958 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 18999 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277 + + PP+ QI + ++K + + TW + Sbjct: 19000 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19043 Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333 + + +K+ GS+ + + EN+ G + VV + P Sbjct: 19044 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19091 Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386 P GTP S++ ++W DGGS V Y +E +W ANK Sbjct: 19092 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19146 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446 T V L Y++RV A N+ G + S+ E P +P + EV++ K Sbjct: 19147 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19205 Query: 1447 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475 + + + K++ + L G++ Sbjct: 19206 LKWSKPHYDGGAKITGYIVERRELPDGRW 19234 Score = 68.6 bits (166), Expect = 6e-11 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%) Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150 S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+ Sbjct: 26630 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26689 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194 ++ S+ I A D G Y AKN GQ + + V + P+ E Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26749 Query: 1195 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235 ++++ +M + + ++S + + + + K A + + Sbjct: 26750 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809 Query: 1236 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 +PP+I P D + G+ + + TG TW Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869 Query: 1276 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ + Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923 Score = 67.4 bits (163), Expect = 1e-10 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%) Query: 1788 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198 Score = 67.4 bits (163), Expect = 1e-10 Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154 P Q+LQ V V GK +S P I W + L T KF+ QE +L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + +A PED +Y C AKND G A S ++V+ PE+ S P +P Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP II +D G+ +V+GT + +W Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 K+I+ S ++ E+ +L I A E G YT + N +G + NL++ Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387 Score = 67.0 bits (162), Expect = 2e-10 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 ++ + V G + + P T WT +G +KT + + + ++I+ L Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11079 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223 D G Y+ N AG + +TV D P P + + T T+ Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11127 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P P I E Q R + +G V+ Sbjct: 11128 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11158 Query: 1284 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336 +GS T L GC + + ENK+G + V K P P G Sbjct: 11159 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11211 Query: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390 P +DI ++ T+SW DGGS + Y +E W NKT F Sbjct: 11212 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11266 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 V L + Y+FRV A N+ G S+PS S+ Sbjct: 11267 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11296 Score = 67.0 bits (162), Expect = 2e-10 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224 A+N +G + ++ V D P + K +M S R S P L G+E + Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 12929 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 K P A +V+ T PIT ++ K I+ E+ Sbjct: 12930 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 12962 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340 + + ENK G + K DPP P Sbjct: 12963 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 12999 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 S+I +T+SW + DGGS + Y +E ++ W ++ + L Sbjct: 13000 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13059 Query: 1399 EYKFRVRAINVYGTSEPSQESE 1420 EY+FRV AIN G +PS S+ Sbjct: 13060 EYEFRVTAINKAGPGKPSDASK 13081 Score = 66.6 bits (161), Expect = 2e-10 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%) Query: 1083 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134 G +D S+ Q ++ L D+ K L+++ S P ++W+ Sbjct: 19667 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19726 Query: 1135 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 L+T ++ + S S++IE A D G Y +N A + V V D P Sbjct: 19727 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19782 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254 PP T D T + A + + PE+ Sbjct: 19783 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19807 Query: 1255 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312 G P+ ++ R + S+ V + N ++L+ + Y V Sbjct: 19808 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19856 Query: 1313 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369 EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E Sbjct: 19857 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 19915 Query: 1370 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429 + K W + A +ST V L + EY FRV A N G S+P + + E+ E Sbjct: 19916 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 19975 Query: 1430 EPKDEVE 1436 P+ +++ Sbjct: 19976 PPEIDMK 19982 Score = 65.9 bits (159), Expect = 4e-10 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8675 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y A N G + +V V D P P L PV+ T + Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8721 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 P+ + + II+ +D K+ T QPI E+E K Sbjct: 8722 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8757 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342 + +T L QE+ + ++ +NK G ++ + VD PP ++ Sbjct: 8758 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8808 Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400 S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y Sbjct: 8809 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8868 Query: 1401 KFRVRAINVYGTSEPS 1416 +FRV+A+N G SEPS Sbjct: 8869 EFRVKAVNEIGESEPS 8884 Score = 65.9 bits (159), Expect = 4e-10 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A N G A+ V V D P P V S+ V P Sbjct: 15039 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15085 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I+Q E ++ W ++Q ++ Sbjct: 15086 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15116 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346 K+T L E+ + ++ NK G + + V+ PDPP P + I Sbjct: 15117 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15172 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+ Sbjct: 15173 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15232 Query: 1405 RAINVYGTSEPSQES 1419 A N G S PS S Sbjct: 15233 MAENAAGISAPSPTS 15247 Score = 65.9 bits (159), Expect = 4e-10 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW + Sbjct: 15519 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15577 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q Sbjct: 15578 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15637 Query: 1418 ES 1419 S Sbjct: 15638 LS 15639 Score = 65.9 bits (159), Expect = 4e-10 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T Sbjct: 22845 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 22903 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K Sbjct: 22904 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 22957 Score = 65.5 bits (158), Expect = 5e-10 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89 +AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488 Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149 L+I +V ++D Y ATN G+ T L VE L Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24530 Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 PK +G V G++ +G+P P +TW KG + + V Sbjct: 24531 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24579 Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268 L +GV + D G Y N G + EL + + R Sbjct: 24580 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24633 Query: 269 SDVRKEVTNVISKESKLD 286 SDV ++ N+ E D Sbjct: 24634 SDVSRDSVNLTWTEPASD 24651 Score = 64.7 bits (156), Expect = 8e-10 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ K + G+ L ++ V P I W +G+ LK T + + + + + I Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 ++ +D G Y A N AG A + V V + P PPV Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 17916 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D + PP QI + +++ T TW Sbjct: 17917 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 17960 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331 + + +K+ + G++ + + EN+ G + V+ +P Sbjct: 17961 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18008 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389 PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F Sbjct: 18009 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18067 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 L EY+F+V A N+ G +PS+ SE + + P Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18109 Score = 64.7 bits (156), Expect = 8e-10 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%) Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68 S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R Sbjct: 26041 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099 Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126 GQ +++ R + + TF I +V D G Y+ N G ++ LT++ + Sbjct: 26100 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157 Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157 K + P K+ R +P ET+P+ + Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214 PPK L KE + + +C + +VTW K L+ + +G Sbjct: 26218 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26275 Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 L+I+ + + D G Y C + G + + + Q S + + ++ SD + Sbjct: 26276 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26335 Query: 275 VTNVISK 281 + V K Sbjct: 26336 ESTVTRK 26342 Score = 64.3 bits (155), Expect = 1e-09 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%) Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308 VR G+++ + +V G TW K K + + + + +L I A + G Y Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11482 Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 + +N G Q + V+D+P P +++ + T+SW +GGS + ++ + Sbjct: 11483 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11541 Query: 1369 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425 E K W +A+ + +LL ++EY FRV A N G P+ E++ + Sbjct: 11542 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11600 Query: 1426 -EKPEEPKD 1433 ++P EP++ Sbjct: 11601 IDRPGEPEN 11609 Score = 64.3 bits (155), Expect = 1e-09 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%) Query: 1215 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269 G +S+ V + P P PP PP I+ D SV L K TG PIT Sbjct: 13664 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13712 Query: 1270 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 ++F R + K K+T L E+ + ++ N G + + Sbjct: 13713 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13770 Query: 1328 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383 V DP P G P +I +S+TL W YDGG + Y +E D +K+W + Sbjct: 13771 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13830 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431 +F V DL+ +Y+FR+RA N G S PS+ +E ++ E P Sbjct: 13831 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879 Score = 63.9 bits (154), Expect = 1e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Query: 1302 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357 QE C Y + EN+ G Q + V + P PP G D+ +S++LSW + Sbjct: 16601 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16659 Query: 1358 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P Sbjct: 16660 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16717 Score = 63.5 bits (153), Expect = 2e-09 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%) Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271 S+ TV + P K P P + + +V+ E + G +V G + + W Sbjct: 15832 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 15890 Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 +K K K E G + + + G +G V P Sbjct: 15891 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 15941 Query: 1332 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389 P G P A + +S+TL W +YDGGS + Y +E + W + + T F Sbjct: 15942 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16001 Query: 1390 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432 V L+ DH Y+FRV A N G SEPS+ + T ++ + P+ Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16045 Score = 63.5 bits (153), Expect = 2e-09 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+ Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20449 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G A + +V + D P P + T T+ +P P Sbjct: 20450 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20496 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 A + I++ E +V W SEH++ E Sbjct: 20497 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20526 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 T + E+ + + NK G + + +VV K P PP G P + I + Sbjct: 20527 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20583 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404 S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV Sbjct: 20584 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643 Query: 1405 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439 A+N G S+ SE + P P ++ ++D Sbjct: 20644 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20680 Score = 63.2 bits (152), Expect = 2e-09 Identities = 33/95 (34%), Positives = 48/95 (50%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+ Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 I DV +D A KA+N GE + A L+V+ + Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383 P P P D SS++L W + DGGS ++ Y +E+ + WK + T Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9266 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D Sbjct: 9267 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9321 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383 + KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ + Sbjct: 10613 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10671 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432 C T + V L YKFRV A+N G S+P+ E V ++ E P+ Sbjct: 10672 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10720 Score = 63.2 bits (152), Expect = 2e-09 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%) Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063 K V +S PLS P L+ K + TL L P+ G AK D + S Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12341 Query: 1064 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104 +EE D + + + + G + +K E++G A +Q L Sbjct: 12342 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12401 Query: 1105 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 + + + GKKL ++ V P T W + T+ + + + S + I Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12461 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215 + +D G Y A+N +G +V V DAP PP + Sbjct: 12462 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12506 Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275 ++DA P + + I+ E V G+ V VT T + Sbjct: 12507 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12557 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335 K I E++ +EN G L K+ AQ V +P Sbjct: 12558 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12602 Query: 1336 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388 T D + ++W DGGS + Y IE +W AN T RST Sbjct: 12603 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12653 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 + L+ EY FR+ A+N G+S PS+ +E T P +P + EV D Sbjct: 12654 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12703 Score = 63.2 bits (152), Expect = 2e-09 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%) Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25141 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163 Y C+ N G EL V+G +++ +T+ + +T + E PP+F Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25195 Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220 L G+ RF IT P+P VTW K ++P + + G+ L I Sbjct: 25196 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25255 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + V DD YT + N G+ S A+L++ Sbjct: 25256 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285 Score = 62.8 bits (151), Expect = 3e-09 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%) Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143 D EK+ + P FK+KL + + +C+++ DP + W +GK L+ Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203 + + E CS+ A D G+ C A N G S + V D E + E + Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760 Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263 + L + E A T K P I+ +PE +V GE+ +VTG Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820 Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323 W + I++S+ +V + L I+ + G + EN G + +V Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879 Query: 1324 NLTVVDKPD 1332 L + + D Sbjct: 1880 KLEIQQRED 1888 Score = 62.8 bits (151), Expect = 3e-09 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386 KP PP P DI SS+ LSW YDGG +Q Y +E D + W Sbjct: 16340 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16398 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 T+ V+ LL HEY FR+ AIN G E + V EK E P ++++ Sbjct: 16399 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16449 Score = 62.4 bits (150), Expect = 4e-09 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14346 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277 + + N +GK S ++++ LD+ +R T T V +TN Sbjct: 14347 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14404 Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325 I ++ ++ A K C+ G S A N +P ++ Sbjct: 14405 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14464 Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385 ++P ++ T S+++L P+P+ G ++ E +R + T T Sbjct: 14465 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14519 Query: 386 QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425 GL Q + +A R P E + + P+ + + Q++ Sbjct: 14520 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14579 Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 K +K V G PKP V W +G + +Q + A S L + + DSG Sbjct: 14580 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14638 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522 Y TA N G++ T+QV + P F V D Sbjct: 14639 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14677 Score = 62.4 bits (150), Expect = 4e-09 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569 AP +KD G+ L C + G P+P I W G+ + +R + + L Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628 + ED G YTC+A N +G+V S S+ LL P P P+ + Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24141 Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688 + GS + + V G P P + W H +Q SE+ E L ++ V + Sbjct: 24142 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24197 Query: 689 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 G Y + N G V A+L V+ +P + P + A L S +IS Sbjct: 24198 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24246 Score = 62.0 bits (149), Expect = 5e-09 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 I +D G +TC VN +G S S L++Q + F +ET A VT Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003 Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309 + E K ++S + + + Q G P A Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035 Score = 62.0 bits (149), Expect = 5e-09 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%) Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329 +++ + V + TI + H + ++ +NK G + + + Sbjct: 9759 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818 Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383 P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A Sbjct: 9819 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 9877 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 S+ V L+ +Y+FRV AIN G S S+ T + P Sbjct: 9878 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 9925 Score = 62.0 bits (149), Expect = 5e-09 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226 Y AKN +G A+ S V V D P P +L T+ + T+ Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11524 Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286 + P D G IT +++RK Q+ + Sbjct: 11525 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11555 Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340 + L A E+ + + ENK+G ++ + + +D+P P A Sbjct: 11556 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11613 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398 D + + L W YDGGS SY +E + W+ + + + T + V + + Sbjct: 11614 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11672 Query: 1399 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 Y+FRV+ N G S+ + E+ V E ++P ++++S Sbjct: 11673 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11711 Score = 61.6 bits (148), Expect = 7e-09 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143 T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++ Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149 Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194 +SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA + Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209 Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238 + E + R + + S ATV+ K P+ PPK + PP Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269 Query: 1239 QI 1240 I Sbjct: 270 SI 271 Score = 61.6 bits (148), Expect = 7e-09 Identities = 35/96 (36%), Positives = 46/96 (47%) Query: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 II D ++T A N G ++ + L VE +E Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505 Score = 61.6 bits (148), Expect = 7e-09 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%) Query: 1308 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364 + ++ EN G + + +D DPP G P +I ++TL W Y GG + Sbjct: 14834 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 14892 Query: 1365 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421 SY +E D N W + F V L D Y+FRV A N G S PS+ S+ Sbjct: 14893 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 14952 Query: 1422 TTVGEKPEEPKDEVEVSDDD 1441 T + E PK +V+V D Sbjct: 14953 ITCRDDVEAPKIKVDVKFKD 14972 Score = 61.6 bits (148), Expect = 7e-09 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PAFK V G+ L + P + W + LK T + + ++I Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15710 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A ED G Y N AG+A + V V D P PP + Sbjct: 15711 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15752 Query: 1218 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 D T PP K G S+ + V T TW Sbjct: 15753 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15794 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331 S ++ TI A R + GC + + EN+ G S TV P Sbjct: 15795 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15841 Query: 1332 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387 P GTP + S+ + W DGGS V Y +E + + W +L T Sbjct: 15842 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 15901 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F L EY+FRV A N+ G +PS+ SE V P +P E + Sbjct: 15902 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 15960 Query: 1448 DYRTVTINTEQKVSDFYDIEERLGSGKF 1475 ++ T + K++ + ++ L G++ Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRW 15988 Score = 61.6 bits (148), Expect = 7e-09 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P +K + VH E K+ + P TI W + L T + + S+S+ Sbjct: 16050 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16106 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217 + A+ D G Y AKN AG+ + V V D P PE P V+ Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16149 Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275 S T +K PP II + +++ E+ L V Q ++C Sbjct: 16150 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16199 Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330 KV G++ T + ++ NK G + + VV K Sbjct: 16200 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16239 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388 PD P P + + S+ + W + DGGS + Y +E D W Sbjct: 16240 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16298 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 V L+ +H+Y+FRV A N G SEPS S Sbjct: 16299 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16329 Score = 61.6 bits (148), Expect = 7e-09 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W+K K + K + G + + + G +G V Sbjct: 18054 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18104 Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388 P P G P A I +++TL W +YDGGS + Y +E D + W + T Sbjct: 18105 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18164 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 F V L+ D Y+FRV A N G SEPS S T ++ + P ++ Sbjct: 18165 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18213 Score = 61.6 bits (148), Expect = 7e-09 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%) Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380 AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W + Sbjct: 21648 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21703 Query: 1381 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435 + + R T F V L +EY+F V A N G S S L E P P V Sbjct: 21704 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21763 Query: 1436 EVSDDDEKEPEVDY 1449 +V+D + +++ Sbjct: 21764 KVTDTSKTTVSLEW 21777 Score = 61.2 bits (147), Expect = 9e-09 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18561 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 + F V L + EY FR+ AIN G EP+ E+ E P+ E++ Sbjct: 18562 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18613 Score = 61.2 bits (147), Expect = 9e-09 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 +HV G+ + L ++ PP W G L+ ++ + + + ++I + D G Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23310 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223 Y KN G + +V + D P P+ E DAT + Sbjct: 23311 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23355 Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283 +P P+ A + +++ + + G + ++ +T + KF + + +E+ Sbjct: 23356 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23405 Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 + + A + G Y +++++ ++ + + P PP T D+ Sbjct: 23406 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23446 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396 +TL+WY DGGS V Y +E W NK + RST L Sbjct: 23447 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23501 Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432 EY+ RV AIN G+ +PS+ S+ + KP+ P+ Sbjct: 23502 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23543 Score = 60.8 bits (146), Expect = 1e-08 Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1861 +E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350 Query: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 D L I++ +D+ YT A N++G+ + TA L +E E E E+E Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401 Score = 60.5 bits (145), Expect = 2e-08 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387 P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T Sbjct: 13092 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13150 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 F V L+ D +Y+FRV A+N G S+PS Sbjct: 13151 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179 Score = 60.5 bits (145), Expect = 2e-08 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Query: 1325 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 + ++P PP D SS L+W +DGGS + Y +E+ + W E Sbjct: 22043 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22101 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 + +F V+ L+ EY+FRV+A N G SEP + + E EP Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22148 Score = 60.5 bits (145), Expect = 2e-08 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P + + K + + C++ G P P++ W+ G + Q ++ D +H L Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24094 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 ++ D G Y+C A+N G++ S L ++ A + P + K + G L Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24151 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589 G PVP +TW + +Q + + T E H+ ++ + H G Y N Sbjct: 24152 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 G V V + +K P KPT PI ++ L + + +S Sbjct: 24212 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24248 Query: 650 PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702 PP + W+ N E +E ++ + C E+ G Y A N+ G Sbjct: 24249 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24308 Query: 703 ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748 + +V+ ++ P + +P KP ++TA SC +A P Sbjct: 24309 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24350 Score = 60.5 bits (145), Expect = 2e-08 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G Sbjct: 26350 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26408 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 F L IH D G YTC N +G+ + +LT++ Sbjct: 26409 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445 Score = 60.1 bits (144), Expect = 2e-08 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384 V KP PP G P D SS++++W YDGGS + Y +EI W+ + A Sbjct: 15256 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15314 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 ++TS+ + L + EYK R+ A+N G EP+ Sbjct: 15315 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15346 Score = 60.1 bits (144), Expect = 2e-08 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 W K K + MKV + G Y + EN G + + V Sbjct: 19136 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19184 Query: 1331 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386 DP P G P ++I S++L W YDGG+ + Y +E + + W + + Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19244 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D Sbjct: 19245 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19300 Score = 59.7 bits (143), Expect = 3e-08 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 EK P F K + + ++ G A + G P P++ WF + + S ++ +D D Sbjct: 3451 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3510 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 + SLII +D+ +YTC A N G+ C+A L + + EG + E E Sbjct: 3511 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3559 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%) Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464 ++ + DS + +P ++ E++ + EVS +L+ TPV + S V Sbjct: 4140 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4199 Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524 ++ L + + +S + S T A ++ + E + E P + L D Sbjct: 4200 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4253 Query: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580 EG L S+ T + W + + + + + L I EDH G Sbjct: 4254 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4311 Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 Y C A N G+ + SA +TV K AP+ + + L+V G Sbjct: 4312 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4354 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 T ++ P W G EI ES+ SL I D G YTC+A N Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4414 Query: 701 AGEVRTQAVLTVQEP 715 G V A LTV P Sbjct: 4415 YGSVSCTATLTVTVP 4429 Score = 58.9 bits (141), Expect = 5e-08 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%) Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189 W T+K TK + EGSL +++ A+N GQ++ + ++D Sbjct: 7633 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7676 Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249 + +++T + PP D T + PPK I ++ ++K Sbjct: 7677 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7727 Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 R G W+K K + +V + G+++ + G Sbjct: 7728 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7768 Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 +G + ++ P P P +D + ++W +GGS + Y Sbjct: 7769 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7822 Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423 +E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE Sbjct: 7823 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 7882 Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456 + +P ++E D E E V +R V + T Sbjct: 7883 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 7920 Score = 58.9 bits (141), Expect = 5e-08 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G+ L+ V P TI W K ++ + + + ++ A+ D G Y Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 A N AG V V D P P V G S+ K Sbjct: 17200 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17242 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288 +PP I + +++ E+ L V ++ +T Sbjct: 17243 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17278 Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343 N K+T L E+ + ++ NK G + + V+ K P PP ++I Sbjct: 17279 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17333 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401 S+T+ W DGGS + Y +E D + W + R T V L DHEY+ Sbjct: 17334 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17393 Query: 1402 FRVRAINVYGTSEPS 1416 FRV A N G EPS Sbjct: 17394 FRVSAENAAGVGEPS 17408 Score = 58.5 bits (140), Expect = 6e-08 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + +F C ++ + V W +G + + ++ D H L + ++ D G Sbjct: 5000 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5056 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ + +G+ + + RL V + F S L+D V EG+ C + + Sbjct: 5057 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5106 Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604 + W N + +R+ + + H + + E L +S V E Sbjct: 5107 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5154 Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664 S+ + + L P F L D ++ ++T+ +VS + P V W +G EI Sbjct: 5155 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5205 Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724 S + + G + L I++ +D G Y C+ G +T+A +TV+ + + Sbjct: 5206 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5256 Query: 725 SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781 KP V +G++ ++ P VH W G+ L + E++++ L+L Sbjct: 5257 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5312 Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827 Q G+ N + +V + S + + REP + Sbjct: 5313 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5372 Query: 828 CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884 L G + G DR+ ++ G + ++ ED + + +HT Sbjct: 5373 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5425 Query: 885 --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938 E IR + + L +D+ K+ V T LS D+++ + + N QR ++V Sbjct: 5426 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5477 Query: 939 S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997 S ++E K HS + F+ L+ TS+ V + + KL G Sbjct: 5478 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5520 Query: 998 S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055 + + + VE + + + S PV K + +KP NA Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5567 Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112 +K+ K+ LKK +K+D+ GT + + + + L V V E Sbjct: 5568 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5624 Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 + + ++S D W L G+ L T + +EG + S+ + + G Sbjct: 5625 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5677 Score = 58.5 bits (140), Expect = 6e-08 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%) Query: 1090 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147 R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + + Sbjct: 18202 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18261 Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207 ++ ++ + D G Y N G V V D P P Sbjct: 18262 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18308 Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267 V G ++ P A + II+ E ++ Sbjct: 18309 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18350 Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 +W + ++Q + K+T L E+ + ++ NK G + + V Sbjct: 18351 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18396 Query: 1328 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381 KP P TP S I S+ ++W DGG+ ++ Y +E D W + Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18456 Query: 1382 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 T V L H Y+FRV A N G EPS+ S Sbjct: 18457 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494 Score = 58.5 bits (140), Expect = 6e-08 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T + Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24092 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 L + +ED G YTC ATN G + + +L ++ + G P+ K G Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24143 Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210 G R GRP P +TW G LQ S +++ Sbjct: 24144 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24181 Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268 L + V + G Y + N G ++ IQ D V E N Sbjct: 24182 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24241 Query: 269 SDV 271 S V Sbjct: 24242 SAV 24244 Score = 58.5 bits (140), Expect = 6e-08 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 1329 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386 +KP P G P + + S ++W + DGG+ +++Y +E + W + T R Sbjct: 24326 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24384 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE Sbjct: 24385 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24435 Score = 58.5 bits (140), Expect = 6e-08 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156 P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++ Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214 I LPED G Y+ A N AG C + V+ + K+ E R + + L Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25417 Query: 1215 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250 GTES +A V KPA T K +I + E++K+R Sbjct: 25418 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25472 Score = 57.8 bits (138), Expect = 1e-07 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1867 PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +IS DD +YT N GE + +A L+ E Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128 Score = 57.8 bits (138), Expect = 1e-07 Identities = 87/371 (23%), Positives = 148/371 (39%), Gaps = 50/371 (13%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384 V KP PP D +S+TL+W YDGGS + Y +EI + + W+ + Sbjct: 17420 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17478 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSELR 17534 Query: 1445 PEVDYR---TVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVW----------A 1491 + R + I+ K +I G+F + +EK A Sbjct: 17535 KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDA 17593 Query: 1492 GKF-FKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERI 1550 GK+ K ++ ++ + +++ P+ + + ++ A +V I+ GG + Sbjct: 17594 GKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNY 17653 Query: 1551 IDEDFELTERECIKYMRQISE---GVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFG 1607 + + E T + + S+ VE + + I + + EN V G ++ +D Sbjct: 17654 VIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV---GVPVETVDAV 17710 Query: 1608 LARRLE-----------NAGSLKVLFGTPEF-----VAPEVINYEPIGYATDMWSI---G 1648 A + S +++ PE V V+ +P G T+ WSI Sbjct: 17711 KAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG--TEKWSIVAES 17768 Query: 1649 VICYILVSGLS 1659 +C +V+GLS Sbjct: 17769 KVCNAVVTGLS 17779 Score = 57.8 bits (138), Expect = 1e-07 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%) Query: 1308 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V Sbjct: 17690 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17749 Query: 1366 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 Y +E+ + W +A + + V L EY+FRV+A N G S+P Sbjct: 17750 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17799 Score = 57.8 bits (138), Expect = 1e-07 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Query: 1790 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD Sbjct: 25276 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 Q + + +I ++ +L I D +D Y A N+ G +C A L VE + + Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395 Query: 1907 GEGEEEEE 1914 E + +EE Sbjct: 25396 QEFKSKEE 25403 Score = 57.4 bits (137), Expect = 1e-07 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1867 P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 ++ + +D A YTC+A N G AT +A L VE E Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286 Score = 57.4 bits (137), Expect = 1e-07 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Query: 1302 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358 QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D Sbjct: 18766 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18825 Query: 1359 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417 GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q Sbjct: 18826 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884 Score = 56.6 bits (135), Expect = 2e-07 Identities = 92/417 (22%), Positives = 146/417 (35%), Gaps = 55/417 (13%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 PA LQD +EG+ QC+VS + W K +K ++F ++Q + I Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEMK--------- 1202 +A PED G Y VA N GQ + +++ +AP S E EMK Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEMEMKEFSSSFLSA 3416 Query: 1203 -------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 + S + L S++ V P K P I+ + + G+ Sbjct: 3417 EEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVSNADISMGDVA 3474 Query: 1256 ELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENK 1315 L V G W + S K + L IL + E G YT + N Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3534 Query: 1316 LGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-----------DGGSAVQ 1364 G L + K + T S + S L + G A+ Sbjct: 3535 YGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIF 3594 Query: 1365 SYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEYKFRVRAINVY 1410 Y++ + TW K+L T S +F V D + + +A N+ Sbjct: 3595 EYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 3654 Query: 1411 GTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDF 1463 G S + E E T + + P + K E +D + P +++EQ+++ F Sbjct: 3655 GESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATF 3711 Score = 56.6 bits (135), Expect = 2e-07 Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%) Query: 921 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978 E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V + Sbjct: 4142 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200 Query: 979 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033 S+ ++K + + S + E K E+ L + GP+ P+ + E Sbjct: 4201 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4258 Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083 + NAK DE K + V + VN + H G Sbjct: 4259 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4317 Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138 T + K + + AP K+K++ + VA G C++ S P W G+ + Sbjct: 4318 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4377 Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198 + + + S+ I + D G Y C A N+ G C+ +TV P E Sbjct: 4378 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4436 Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 + R+P+ VL + ++K+P PK PK + PE + E V Sbjct: 4437 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4492 Query: 1256 EL 1257 E+ Sbjct: 4493 EV 4494 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10096 Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228 +AKN+AG+ + + V V D P T P + S Sbjct: 10097 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10136 Query: 1229 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287 ++ F PED G PIT ++ +++ V Sbjct: 10137 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10170 Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341 + T+ Q + + EN +G + +A V + P+ P Sbjct: 10171 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10229 Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399 ++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L Sbjct: 10230 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10289 Query: 1400 YKFRVRAINVYGTSEPS 1416 Y++RV A+N+ G +PS Sbjct: 10290 YEYRVSAVNIVGQGKPS 10306 Score = 56.6 bits (135), Expect = 2e-07 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + ++ V P T+ W + LK T+ + + ++I + + D G Y Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 A+N G+ + V D P PP + D Sbjct: 14643 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14673 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 + + F D G V Q + TW++ + + + Sbjct: 14674 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14722 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346 ++LT Q + + +N+ G + +V P PP GTP + + Sbjct: 14723 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14776 Query: 1347 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404 S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV Sbjct: 14777 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14836 Query: 1405 RAINVYGTSEPSQESE 1420 A N+ G S+PS+ SE Sbjct: 14837 IAENMAGKSKPSKPSE 14852 Score = 56.6 bits (135), Expect = 2e-07 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%) Query: 1057 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115 E L ++ E + KND A ++ K + + TA Q + G Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22168 Query: 1116 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175 + +S P + W L LK T + ++ +++++ ++ D G Y +N Sbjct: 22169 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228 Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235 AG S V V P P + V +++ V PK Sbjct: 22229 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275 Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295 + I++ E T W ++ ++ K+ Sbjct: 22276 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22305 Query: 1296 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351 T L E+ + + EN+ G S+ + + + P P P + + ++++++ Sbjct: 22306 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22363 Query: 1352 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409 W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N Sbjct: 22364 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423 Query: 1410 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 G S+ S+ S + + P + EV+D Sbjct: 22424 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22452 Score = 56.2 bits (134), Expect = 3e-07 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387 P P P +D S +L+W YDGG + Y +E ++ W + T R T Sbjct: 14175 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14234 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447 F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+ Sbjct: 14235 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14285 Query: 1448 DYRTVTINTEQKVSDFYDIEER 1469 RT+ + + F I+ R Sbjct: 14286 -RRTLVVRAGLSIRIFVPIKGR 14306 Score = 55.8 bits (133), Expect = 4e-07 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%) Query: 1777 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1834 P +++E E ++ A ++K KP + V+EG ARF C++ G Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820 Query: 1835 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878 Query: 1895 AELIVETMEE 1904 +L ++ E+ Sbjct: 1879 VKLEIQQRED 1888 Score = 55.8 bits (133), Expect = 4e-07 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%) Query: 1306 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359 GC + ++ EN+ G + V + P PP DI S+++L+W +DG Sbjct: 14437 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14495 Query: 1360 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419 GS + Y IE + W + T + V++L EY F+V A+N G S P +ES Sbjct: 14496 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14554 Query: 1420 ELTTVGEKPEEPK 1432 V E+ P+ Sbjct: 14555 RPVIVKEQTMLPE 14567 Score = 55.5 bits (132), Expect = 5e-07 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 AP F Q LQ V V EG + +S P + W +G+ + T+ + +S Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 ++I + G Y A N +GQA + ++ V A Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274 PP +Q + VR G V L +VTG + + Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140 Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 +IQ S ++ + L I A E G Y++ N +G + L V + + P Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200 Query: 1335 A 1335 A Sbjct: 201 A 201 Score = 55.5 bits (132), Expect = 5e-07 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1863 P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 LII+ V DD Y +A N G + TA L VE Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523 Score = 55.5 bits (132), Expect = 5e-07 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F R + EG F C+I G P PE+ WFK++ I S + I + SL Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26695 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I + D KYT KA N G+ + TA L+V + E Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731 Score = 55.1 bits (131), Expect = 7e-07 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388 P PP P +D SS L W DGGS V Y +E + + W++ R T Sbjct: 9925 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 9982 Query: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D Sbjct: 9983 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10035 Score = 55.1 bits (131), Expect = 7e-07 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386 KP P P D + L W DGGS + Y +E W + R Sbjct: 11305 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11364 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441 +F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419 Score = 55.1 bits (131), Expect = 7e-07 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%) Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268 TES + K K P PP++ + +++ E G +TG + + Sbjct: 11885 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 11942 Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328 W+ K MKV+N +H + + EN++G + + V Sbjct: 11943 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991 Query: 1329 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378 DP P G P D S+TL W YDGG+ + Y +E+ S ++ W Sbjct: 11992 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051 Query: 1379 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 K A F V L + EY+FRV A N G P++ E E E P+ ++ Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111 Query: 1436 EVS 1438 + S Sbjct: 12112 DAS 12114 Score = 55.1 bits (131), Expect = 7e-07 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 1342 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399 D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L + Sbjct: 23148 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23207 Query: 1400 YKFRVRAINVYGTSEPSQESELTTV 1424 Y FR+RA N G SEP + TV Sbjct: 23208 YLFRIRAQNEKGVSEPRETVTAVTV 23232 Score = 55.1 bits (131), Expect = 7e-07 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567 AP F L++ V + L C V G P P + W G+ I +Y + G + Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I +D Y A N G VS +A + V P+K P L+ Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24535 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687 G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24591 Query: 688 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734 +D G Y A N G + V V +P G + +S+ + AS Sbjct: 24592 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24651 Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA 760 G S + + + WLR G+A Sbjct: 24652 GGSKITNYIVEKCATTAERWLRVGQA 24677 Score = 54.7 bits (130), Expect = 9e-07 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383 PDPP I +++ LSW DGGS V Y +E WD + + W++ Sbjct: 9515 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9573 Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431 F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9620 Score = 54.7 bits (130), Expect = 9e-07 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101 + G + K + G P P + W+++ + + + L C + T L + + DR Sbjct: 20388 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20443 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 G Y + N G+ T+ + + G P+ KT+ E +W Sbjct: 20444 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20495 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204 K+ +V++ + R + + +KGN + +P Sbjct: 20496 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20555 Query: 205 ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260 SV KN G+ + + + VV A +++S ++ D + + Sbjct: 20556 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20615 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320 + K T D R++VT + + + C+ G P +P Sbjct: 20616 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20661 Query: 321 KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378 K D P + + T SSITL ++ + G V GEE + Sbjct: 20662 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20721 Query: 379 PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421 T + PG+ VS A + P+E P+ Sbjct: 20722 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20781 Query: 422 -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478 S K + V+ G P P V W + + GS Y E+ S L + Sbjct: 20782 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 20837 Query: 479 TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528 TR D+G Y T N G+ S T+ V ++L V V+ ++L D +I+G Sbjct: 20838 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 20896 Query: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 ++ + + TW + + + D + + LAEN Sbjct: 20897 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 20947 Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637 +G E PV ++ API + D DG Sbjct: 20948 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 20993 Query: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697 V V E W H G I ++ + Q Q L + + G Sbjct: 20994 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21050 Query: 698 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 + G + + ++ E P VT +G +V + G P P++ WL+D Sbjct: 21051 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21103 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817 G L K++ + E+ TL +K + H G+Y ++L N V C V + + Sbjct: 21104 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21160 Query: 818 ALPRG 822 + P+G Sbjct: 21161 SKPKG 21165 Score = 54.7 bits (130), Expect = 9e-07 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%) Query: 1308 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365 + + EN G S T+ P P GTP D+ ++TL W DGGS + Sbjct: 21332 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21391 Query: 1366 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419 YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S Sbjct: 21392 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447 Query: 1420 ELTTVGEKPEEP 1431 + ++ P Sbjct: 21448 GIIMTRDENVPP 21459 Score = 54.3 bits (129), Expect = 1e-06 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Query: 1797 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 +EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ + Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557 Query: 1857 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912 I + G +L I D A YT A+N G T ++ VE +E E E E + Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613 Score = 54.3 bits (129), Expect = 1e-06 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447 G+ + +V K + R+ + G R KF S + Q VKE +T F CE+S K V W Sbjct: 5055 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5109 Query: 448 FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507 F + ++ + + +H L + + D +L Sbjct: 5110 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5159 Query: 508 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565 V+E P F+ L D +E + L+C V VP + W +G+ I S G+ Sbjct: 5160 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5217 Query: 566 AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 L I+ A +D G Y C G A VTV + + KP Sbjct: 5218 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5259 Query: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684 L ++V G +++S P W G + S D + G +H L + Sbjct: 5260 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5314 Query: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744 TG + +A N+ ++ A L V+E FI+ V C + Sbjct: 5315 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5366 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782 + +P T WL+ + + D FE++++ ++V+K Sbjct: 5367 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5402 Score = 54.3 bits (129), Expect = 1e-06 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158 F+ KL + G+ L + S P + W + L+ + I + +L I Sbjct: 10327 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10382 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218 KA D G Y V +N G + CQV V D P PPV Sbjct: 10383 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10424 Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278 D K P I +K G+ V + + + TC K K + Sbjct: 10425 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10480 Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338 + +++ ++EN Y + S +A+ V D PD P T Sbjct: 10481 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10525 Query: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395 D S ++W +DGG + +Y +E ++ +K W + T F V DLL Sbjct: 10526 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10580 Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448 +Y+FRV A N G +PS S+ + +P V D VD Sbjct: 10581 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10633 Score = 54.3 bits (129), Expect = 1e-06 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QL PV++K L PP F V G+ + GRP Sbjct: 15636 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15678 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242 P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732 Score = 54.3 bits (129), Expect = 1e-06 Identities = 26/77 (33%), Positives = 44/77 (57%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803 Query: 232 TCLVVNGSGKASMSAEL 248 V N G+ + S E+ Sbjct: 16804 GITVANVVGQKTASIEI 16820 Score = 54.3 bits (129), Expect = 1e-06 Identities = 25/72 (34%), Positives = 40/72 (55%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G+ + + GRP+P ++W+K PL+ + RV+V E VL I N+DD G Y Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885 Query: 232 TCLVVNGSGKAS 243 T N +G A+ Sbjct: 17886 TVTATNSAGTAT 17897 Score = 54.3 bits (129), Expect = 1e-06 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1865 P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I+ V DDDA+YT A N GE +C A+L V Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285 Score = 53.9 bits (128), Expect = 1e-06 Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%) Query: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 +S + + A L V P +K + I LEV G A+F C+I+ P+ WFK Sbjct: 4319 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4374 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 + I ES I + + SL I D +YTCKA N G +CTA L V T+ GE Sbjct: 4375 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4432 Score = 53.9 bits (128), Expect = 1e-06 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 ++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16514 Query: 232 TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260 T + N SG + SA ++++ LD+ + Sbjct: 16515 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16572 Query: 261 VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311 V + +AT VTN K+D L+ A P + P A Sbjct: 16573 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16632 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363 PQPP + ++ + + T S I +Q + R L Sbjct: 16633 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691 Query: 364 LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411 + + GEE K + PR P + ++D+V + Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16732 Query: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471 P + S V+ Q +K +SG PKP + W +G P+ +Q I V + Sbjct: 16733 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16789 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCS 499 L + + D G Y T +N GQ + S Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTAS 16817 Score = 53.9 bits (128), Expect = 1e-06 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E A E KP ++D V S A+F K G P P +W KD ++I + +++ Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908 D+ G L I D YTC NS G + + +L ++ +++ E + Sbjct: 26404 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453 Score = 53.1 bits (126), Expect = 2e-06 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV+ G R GRP P++TW + + +V + + L I +++D G Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17594 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289 Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D Sbjct: 17595 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17646 Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328 AK KN +R + AN + + S K+E+ + Sbjct: 17647 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17705 Query: 329 ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375 P + P L +TS+S+ + R G V + P G E K Sbjct: 17706 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17764 Query: 376 PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423 GL S KA N + +P+ + + P + + Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17824 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 ++ + +K V G P+P ++W +G P+ +Q + V E A S L + + D G Sbjct: 17825 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 17883 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 Y+ TA+N+ G + + ++ V V P F V D VI Sbjct: 17884 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 17927 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/82 (29%), Positives = 41/82 (50%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530 Query: 230 VYTCLVVNGSGKASMSAELSIQ 251 VYT N SG A ++ +Q Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + + Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +++ +D+ YTC A N +GE +++L+++ Sbjct: 24096 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24126 Score = 52.8 bits (125), Expect = 3e-06 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 PT + + V G V + + ++G PPP W G++++ESE E Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734 L I+E DTG YT E N G T V+ + +P T P I + S+T S Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23358 Query: 735 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790 G + L + WL +++ + T F L + + + + G Sbjct: 23359 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23418 Query: 791 QYEILLKNRVGECSCQVSL 809 Y L++ V EC + + Sbjct: 23419 SY---LQSEVIECRSSIRI 23434 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90 AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094 Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127 LVI +D G+YT N G + L E + Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131 Score = 52.4 bits (124), Expect = 4e-06 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 1781 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1840 ++A+ + D Q + +A++ + P F V+ G + D G P P V Sbjct: 15624 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15682 Query: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV Sbjct: 15683 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740 Score = 52.4 bits (124), Expect = 4e-06 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%) Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280 K P TP PP+ P + SV L K G +T +++ ++ + Sbjct: 23818 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 23877 Query: 1281 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332 H K + + +T L E+ + ++ +N +G S + + VV DKP Sbjct: 23878 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 23935 Query: 1333 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390 P S I S+TL W DGG + Y +E S + WK+ + F Sbjct: 23936 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 23994 Query: 1391 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438 + LL EY+FRV A N G S P S +++LT+ GE P K+ +V+ Sbjct: 23995 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24046 Score = 52.4 bits (124), Expect = 4e-06 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P F+ + ++ V+ C+V+G PKP V W+ +G + + E G ++ Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490 Query: 474 LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 ++ + T D T Y A+N G +S + +L+VE A + + P + + G+ Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24549 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587 ++ G P P ITW GQ + + V P +D G Y A+N Sbjct: 24550 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24608 Query: 588 ALG 590 G Sbjct: 24609 RFG 24611 Score = 52.4 bits (124), Expect = 4e-06 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G Sbjct: 25081 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25140 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264 Y C VVN G+ S AEL ++G+ + R T Sbjct: 25141 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25175 Score = 52.0 bits (123), Expect = 6e-06 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%) Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164 ++ H+ G L L + P + W + T I ++ GS + I A ED Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10786 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 G+Y +N AG S +V V D P P+ + +S K Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10834 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 +P G SV V + W ++ H Sbjct: 10835 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10872 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341 +E L +AA EN+ G + DP P G P Sbjct: 10873 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 10920 Query: 1342 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399 D+ + ++L W DGGS + Y +E + + W + T + V L Sbjct: 10921 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 10980 Query: 1400 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437 Y+FRV+A N+ G P + EK P E++V Sbjct: 10981 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11017 Score = 52.0 bits (123), Expect = 6e-06 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21529 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145 G YT EA N SG+ + +++ V+ + K +G + G++ + Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573 Score = 51.6 bits (122), Expect = 7e-06 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%) Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469 ++A P F + QS V++ V+ + V+GIP P V ++ +G + + ++ ++ Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158 Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505 + L + +A DSGTYS A+N+ G+ + + L V+ Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 51.6 bits (122), Expect = 7e-06 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%) Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327 W K K + + H KV G + + EN G + Sbjct: 20219 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20267 Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +D +PP +DI +S++LSW ++DGGS + Y +E D + W + Sbjct: 20268 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20326 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417 T F + L + +Y+FRV A N G+ S PS+ Sbjct: 20327 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20359 Score = 51.2 bits (121), Expect = 9e-06 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385 + P PP P +D S+++ L W +++GG + Y ++ W + Sbjct: 8503 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8560 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + V+++ +YK RV A+N G P E++ TV E E P E++VS Sbjct: 8561 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8612 Score = 50.8 bits (120), Expect = 1e-05 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%) Query: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183 PP T+ W + K L + + S ++I + D G Y +N G+ + S Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20861 Query: 1184 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238 V V D PA+ + SR + L PP++ S + ++K+ A K Sbjct: 20862 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 20913 Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298 TW + + ++ SE Sbjct: 20914 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 20939 Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356 + +L EN++G + V + PA S D +S+ LSW Sbjct: 20940 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 20990 Query: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 +DGGS + Y +E +TW ++ V L +FRV A N G S+P Sbjct: 20991 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21050 Query: 1417 QESELTTVGEKPEEPKDEVEVSD 1439 + TV E P EV++SD Sbjct: 21051 TIGPI-TVKELIITP--EVDLSD 21070 Score = 50.8 bits (120), Expect = 1e-05 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%) Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343 SE K+T L E+ + ++ EN G A L +P P G P +D Sbjct: 21711 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21768 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401 ++++L W +DGG + Y IE+ + W ++ C T + V DL EYK Sbjct: 21769 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21828 Query: 1402 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 FRV AIN G + + + ++ P+ +++ + Sbjct: 21829 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21865 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777 G P + + VT LG++ +SC I G P P + W R GK L + + +++ + Sbjct: 24033 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24091 Query: 778 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 TL + + G Y + N VGE L+LQ Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126 Score = 49.7 bits (117), Expect = 3e-05 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%) Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 S P E + E P F L + VK G +TG+P+P++TW K ++ L+ Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252 R+++ + I + D G Y VN G+A+ E+++ Sbjct: 7236 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7295 Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 D N S + D ++TN + + DS Sbjct: 7296 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7330 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384 P PP G P S+ +SW +GGS + Y +E + + W ++ Sbjct: 9102 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9160 Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439 + FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D Sbjct: 9161 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9218 Score = 49.7 bits (117), Expect = 3e-05 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171 G + L V PP I W+ L+ + + + E D G Y Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13270 Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231 +N G+ E + V V D P PPV T + + P Sbjct: 13271 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13312 Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291 P II + ++ + K T C+ FR V N E Sbjct: 13313 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13355 Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348 G + + EN+ G V P G +RS SS Sbjct: 13356 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13403 Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408 ++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13462 Query: 1409 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443 G P SE+T V +D+V D D K Sbjct: 13463 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13488 Score = 49.7 bits (117), Expect = 3e-05 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+ Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16799 Query: 789 AGQYEILLKNRVGECSCQVSLM 810 GQY I + N VG+ + + ++ Sbjct: 16800 GGQYGITVANVVGQKTASIEIV 16821 Score = 49.7 bits (117), Expect = 3e-05 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G Sbjct: 18620 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18677 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277 Y + N SG S +A ++++ LDS + +RE K + D ++TN Sbjct: 18678 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18735 Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330 I ++ + A + NC+ Q G S + + + E+ + Sbjct: 18736 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18795 Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383 + P P + T +T A ++ E + G V + K + T Sbjct: 18796 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18855 Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431 GL G + V AA R P E KP + VK + + Sbjct: 18856 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 18915 Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491 K G P+ V W +G + ++ + V L + +A D GTY SN Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 18974 Query: 492 AQGQLSCSWTLQV 504 + G ++ T+ V Sbjct: 18975 SAGSITVPITIIV 18987 Score = 49.3 bits (116), Expect = 4e-05 Identities = 24/81 (29%), Positives = 40/81 (49%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867 Query: 230 VYTCLVVNGSGKASMSAELSI 250 YT N SG S + +L + Sbjct: 12868 DYTITAENSSGSKSATIKLKV 12888 Score = 48.9 bits (115), Expect = 5e-05 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%) Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190 W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975 Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250 P PP S+ + +K TPP I + +++ Sbjct: 13976 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14015 Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310 E+ L W + IQ H+ + + G++ + H G Sbjct: 14016 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14056 Query: 1311 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368 G + +VD+ P P P S++ ++ T+SW DGGS + Y + Sbjct: 14057 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14111 Query: 1369 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426 E + + W + V L Y+FRV A N G PS+ S+ + + Sbjct: 14112 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14171 Query: 1427 K--PEEPKDEVEVSDDDEK 1443 P P V+D +K Sbjct: 14172 AAYPPGPPSNPHVTDTTKK 14190 Score = 48.5 bits (114), Expect = 6e-05 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%) Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62 I++T++++ P S P+T A +PPR L +K G + V G P P Sbjct: 12770 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12828 Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++ Sbjct: 12829 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885 Query: 121 LTV 123 L V Sbjct: 12886 LKV 12888 Score = 48.5 bits (114), Expect = 6e-05 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%) Query: 1325 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382 + +D PP P +D +S++L+W +GGS V Y IE+ W + Sbjct: 23527 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23584 Query: 1383 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436 C +T +++ H EY+FRV A N G EP++ V E E P E++ Sbjct: 23585 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23642 Score = 48.1 bits (113), Expect = 8e-05 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566 + + PS ++ G+D ++ V G P P I+W+ +G+P+ Q R E A Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870 Query: 567 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 LHI++ +D G YT A N+ G + + V V EK Sbjct: 17871 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907 Score = 48.1 bits (113), Expect = 8e-05 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 +QLG PV+++ +E +PS+ E P F T VK + + GRP Sbjct: 18883 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 18925 Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ + Sbjct: 18926 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 18983 Query: 249 SIQGLD 254 +I LD Sbjct: 18984 TIIVLD 18989 Score = 48.1 bits (113), Expect = 8e-05 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%) Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163 C TN ELT + + + V ++ D S P+ T P I + PP+ Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19292 Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 + +VVK G++ + + I GRP P ++W K + ++ AR + + +L + Sbjct: 19293 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19352 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + D G Y + N +G S++ + Sbjct: 19353 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382 Score = 48.1 bits (113), Expect = 8e-05 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%) Query: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810 AV + + S M S + KS L++ + + ++ A LE + E+ Sbjct: 25998 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26057 Query: 1811 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 T+ R + V EG +ARF C +G P P V W + Q + S Q+ + Sbjct: 26058 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26116 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + IS V D+ Y+ NS G+ L ++ Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154 Score = 47.8 bits (112), Expect = 1e-04 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1859 +++ KP+F K + L + A F+C++ DP +V W D + + + ++ Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708 Query: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +E G CSL D TC+A N G +A LIV+ Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749 Score = 47.8 bits (112), Expect = 1e-04 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%) Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322 G P+T ++ ++++ KV + + T+ Q + + NK G + Sbjct: 7018 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076 Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376 VN+ T PDPP D ++S+ L+W DGGS ++ Y +E + Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7135 Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435 W T V L Y +RV+A+N G S+PS+ +E + E P+ + Sbjct: 7136 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7195 Query: 1436 EV 1437 +V Sbjct: 7196 DV 7197 Score = 47.8 bits (112), Expect = 1e-04 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%) Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478 K ++ + G P P+ +W +G + ++G ++ EDA S + + + + Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385 Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531 +G YS TA N GQ + + ++V + L V ++ + +G D Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9444 Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 ++G + + T ++G+ C G + D L E + AEN G Sbjct: 9445 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9495 Query: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651 V ++ ++R P+ P P +K+ G TV +S PP Sbjct: 9496 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9538 Query: 652 PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 + W G + + + ++ + ++++ + +A Sbjct: 9539 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9597 Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756 N+AG + A + + P I + G +V I I G PFPT+ W + Sbjct: 9598 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9657 Query: 757 ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 D K H L +D TLV+ + + G Y I N +G S ++ L Sbjct: 9658 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9714 Score = 47.8 bits (112), Expect = 1e-04 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%) Query: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630 P D + +A NA+G +S S+ S ++ V P P + GL Sbjct: 21423 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21472 Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690 + G + + V G P P V W +G EI++ + SL +++ + Sbjct: 21473 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21529 Query: 691 GTYTCEAWNSAGEVRTQAVLTVQE 714 G YT EA N++G + + + VQ+ Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQD 21553 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385 +++P PP +SD SS+ L W DGGS + Y IE + W + Sbjct: 6792 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6850 Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440 ++ V L ++Y +RV A N G S+PS+ T + EP ++ D Sbjct: 6851 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 6905 Score = 47.4 bits (111), Expect = 1e-04 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Query: 574 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632 +P++ T T L E A Q A V+ S S+ + +A + P + + S L Sbjct: 12749 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12808 Query: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689 V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12865 Query: 690 TGTYTCEAWNSAG 702 +G YT A NS+G Sbjct: 12866 SGDYTITAENSSG 12878 Score = 47.4 bits (111), Expect = 1e-04 Identities = 25/82 (30%), Positives = 36/82 (43%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 + KE R I G+P P V+W KG PL RVSV L ++ + D G Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555 Query: 231 YTCLVVNGSGKASMSAELSIQG 252 YT + N +G + + + G Sbjct: 13556 YTITLKNVAGTKEGTISIKVVG 13577 Score = 47.4 bits (111), Expect = 1e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 L I +++D GKYT ATN +G + + V Sbjct: 17871 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904 Score = 47.4 bits (111), Expect = 1e-04 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 NA S S + E P + + + L + G + R ++G P P V Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21494 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+ Sbjct: 21495 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552 Score = 47.4 bits (111), Expect = 1e-04 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102 I+ G+ + V G PEP++ W + + + + L G R T VI D G Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22619 Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158 KYT N SG + V+V + V S G+ VS+ ++ +S P + I Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22678 Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213 + T V+ EG+ S +T + +V + P P + +N Sbjct: 22679 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22738 Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269 + G+ ++ G ++ ++ E+S +D + +R T+ Sbjct: 22739 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22798 Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327 D R +VT+++ + C R + A NS+P S SC++ Sbjct: 22799 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22841 Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376 P +AP+ V+ T SI+L + + +G + E+ A Sbjct: 22842 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 22899 Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420 R F +G + AA + ++G + + E +P Sbjct: 22900 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 22956 Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479 ++ ++ +++ VSG P P + W +G + S + + S+ L ++ K Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23012 Query: 480 RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 D+G Y+ A N G+ S + ++V + V EV+ ++ + I+G Sbjct: 23013 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23068 Query: 533 LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590 G PV I + T + I + + L EN G Sbjct: 23069 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23122 Query: 591 --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 S V V E +P+ P+K L+V+D ++ T+T ++ Sbjct: 23123 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23158 Query: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705 P L++G + GT+ + + + P E T T E +R Sbjct: 23159 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23213 Query: 706 TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752 Q V EP + + R ++ G+ V + IAG P P Sbjct: 23214 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23273 Query: 753 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 W G L +++ V + V L +++ G+Y + LKN G S + +++ Sbjct: 23274 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23332 Query: 813 NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853 + A ++ EP + GG G ++ + RPGW Sbjct: 23333 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23382 Score = 47.4 bits (111), Expect = 1e-04 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387 P PP G P + + W DGG+ + +Y ++ + + W + T Sbjct: 22743 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22801 Query: 1388 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431 V L+ +Y+FRV A+N G SEPS+ S + E P Sbjct: 22802 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22845 Score = 47.4 bits (111), Expect = 1e-04 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63 V + S S++ ++P +P E + + + I+ GA+ + V G P P Sbjct: 22923 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 22980 Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 +TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V Sbjct: 22981 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23037 Score = 47.0 bits (110), Expect = 2e-04 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%) Query: 988 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045 ++++ + +GS E + VES +S + S V K + +A ++ Sbjct: 4141 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200 Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105 K + KP E + +S E ++V V + G + P L Sbjct: 4201 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4250 Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164 D EG + L +++ + W K + + + Q+ + ++ I+K ED Sbjct: 4251 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4308 Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224 +G Y C A ND+G+ S ++TV K Sbjct: 4309 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4333 Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 + AP K E +V G + ++ + W K ++I ES+ Sbjct: 4334 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4383 Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 + +S+ S L IL + CG YT N+ GS LTV Sbjct: 4384 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426 Score = 47.0 bits (110), Expect = 2e-04 Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%) Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810 V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L Sbjct: 4272 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4330 Query: 811 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870 + +A + R EP ++ G + ++R W G+ + E D +R Sbjct: 4331 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4386 Query: 871 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917 +L+ +V + ++T +A + L G+K K L E K Sbjct: 4387 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4444 Query: 918 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963 P E++ ++ L++ + +PK ++ KV P ++V+ +V ++ Sbjct: 4445 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4502 Query: 964 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023 K P P KVP KPA P LPA E A+ P +P+ Sbjct: 4503 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4548 Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083 PV P K A E KP G P + + + ++ + + G Sbjct: 4549 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4603 Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137 + + + F ++++D+ + E G + +C VS P+T I W +G Sbjct: 4604 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4660 Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 ++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P Sbjct: 4661 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4714 Score = 47.0 bits (110), Expect = 2e-04 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%) Query: 1111 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169 EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+ Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143 Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228 C ND G+ ++ V + + RR T+KK K Sbjct: 25144 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25183 Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285 T PP+ ++ GE+V +T TW K ++I+ ++ K Sbjct: 25184 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25243 Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334 E+ + +LTI + + YT++ NK G + LTV P P Sbjct: 25244 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25303 Query: 1335 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384 G +IR S + TL W DG +IEI + Sbjct: 25304 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25354 Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444 + +++D LP+ +RV A N G++ ++ + K +E K + E +K+ Sbjct: 25355 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25411 Query: 1445 PEVDYRTVTI 1454 + R I Sbjct: 25412 IDKTLRMAEI 25421 Score = 46.2 bits (108), Expect = 3e-04 Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F+ + + +G A FE V G P P VTW + + + + + + G+ + + Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144 ++ ED G Y C+A N G EL V P +K+ + Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3694 Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 PAVE S + AT + ++K + + +++ + L +PL Sbjct: 3695 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3749 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260 S+ E++ + + + C +NGS S L +Q + S ++F Sbjct: 3750 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3798 Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311 + ET+A SD K + +S E +++SL + P+ G P Sbjct: 3799 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3852 Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353 S +PP S L S + +P+ + T+ +TLQ Q Sbjct: 3853 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 3895 Score = 46.2 bits (108), Expect = 3e-04 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%) Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444 GLG D IP+E Q P E + E VK TV+F + G+P P Sbjct: 10992 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11044 Query: 445 VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504 W +G+ ++ E V D S L + RD+G Y T SNA G + + L V Sbjct: 11045 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103 Score = 46.2 bits (108), Expect = 3e-04 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 LP KE + + + ++G P P V+W + P+ + R ++ T +L+++ Sbjct: 13490 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13548 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125 + D GKYT N +G ++ T+ + V G Sbjct: 13549 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13577 Score = 46.2 bits (108), Expect = 3e-04 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%) Query: 1768 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1822 S ++ + P+ P E++ E V + A + +K SK I L VVE Sbjct: 26184 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26243 Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C Sbjct: 26244 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26294 Query: 1883 K 1883 + Sbjct: 26295 E 26295 Score = 45.8 bits (107), Expect = 4e-04 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%) Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163 L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I + Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188 D G YK + G+ E +C ++V+ Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485 Score = 45.8 bits (107), Expect = 4e-04 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864 PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I + Sbjct: 5875 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 5930 Query: 1865 CSLIISDVCGDDDAKYTCK 1883 L+I+ DD+A+Y+C+ Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949 Score = 45.8 bits (107), Expect = 4e-04 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565 ++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G Sbjct: 21460 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21516 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602 L ++DA + G YT A+NA G V V + Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553 Score = 45.4 bits (106), Expect = 5e-04 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862 E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++ Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + L+I D KYT A G TA+L VE Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097 Score = 45.4 bits (106), Expect = 5e-04 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%) Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169 RQ TV+ EG+ K V + G P ET+P E A +L G Sbjct: 8562 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8616 Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + + G+ R +TGRP P W K L RV + L I + D G Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8675 Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 Y N G +A L ++ + + + + D E+T I Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8735 Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327 K++K+ + +E + + G + ++ + PP E D Sbjct: 8736 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8795 Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381 P T+P+ ++T S+ITL EPR+ G + E++R P Sbjct: 8796 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8851 Query: 382 FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423 PT + + D KA N +P+ Q D P + + + Sbjct: 8852 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 8911 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478 +VK + V +V+G+P P++ W T + + ++++ ++ S L + KA Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971 Query: 479 TRDSGTYSCTASNAQGQL 496 D GTY+ TASN G + Sbjct: 8972 REDKGTYTVTASNRLGSV 8989 Score = 45.4 bits (106), Expect = 5e-04 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%) Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567 +V P+FSS +V GQD ++ + G P P ITW +G P++ T + Sbjct: 16734 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627 L I++ +D G Y N +GQ + S + +K P P P+ Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 16836 Query: 628 GLSDLKVMDGSQVTMTVQVSGNPP 651 +S ++ +S NPP Sbjct: 16837 DVS----------AESITLSWNPP 16850 Score = 45.4 bits (106), Expect = 5e-04 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 + G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885 Query: 694 TCEAWNSAG-EVRTQAVLTVQEP 715 T A NSAG +V+ +++P Sbjct: 17886 TVTATNSAGTATENLSVIVLEKP 17908 Score = 45.1 bits (105), Expect = 7e-04 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 +K G + E V G P P + W ++G+ + + + T +LV D G Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15034 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160 YT ATN G FAK + V G + V + + P Sbjct: 15035 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15081 Query: 161 P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215 P K+ +V++ + R + + QVT LK L+ + RV K G+ Sbjct: 15082 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15140 Query: 216 -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256 VL ++ D + C S S ++ D A Sbjct: 15141 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15200 Query: 257 NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315 + +++ K T +D+R +V+ + E + + A + SP +P Sbjct: 15201 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15260 Query: 316 PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366 PP + L++ + S A P+ S PE P A GL S Sbjct: 15261 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15319 Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423 + + + GLG +V KA +R +P E + D+ K + Sbjct: 15320 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15374 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481 ++ T++ + G P PEV W + E + ++ S Y L+ D Sbjct: 15375 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15428 Query: 482 SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534 SG Y T N+ G S ++V + L V EV + ++ D +++G + Sbjct: 15429 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15488 Query: 535 CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593 V R + + C ++ D L E Y LAEN G + Sbjct: 15489 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15537 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 A K S R P+ P K T +MD ++ +V +S P Sbjct: 15538 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15576 Query: 654 VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 H+G + +G+ + + C E T T + + V Q + Sbjct: 15577 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15632 Query: 713 QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 +P + P I+K + T G+ + + G P P V W +D L Sbjct: 15633 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15691 Query: 762 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802 K T E+ L +K G Y + L N GE Sbjct: 15692 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15731 Score = 45.1 bits (105), Expect = 7e-04 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%) Query: 1228 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284 P PP A P++ + +R E G I W+ K R I + Sbjct: 22340 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22394 Query: 1285 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 KV E K+T L E+ Y L + +A + + D P G P +D+ Sbjct: 22395 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22453 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398 S+++L W +YDGGS V Y IE + + + W + F V L Sbjct: 22454 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22513 Query: 1399 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436 Y+FRV A N G S+ S+ + T ++ PK E++ Sbjct: 22514 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22552 Score = 44.7 bits (104), Expect = 9e-04 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%) Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 W+ +G+ I+ES F G L I +V D G YTC E + A L V+E Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713 Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775 + + VT GQ + +SC + + V W +DGK + + G Sbjct: 4714 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4768 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810 + L + AG Y + ++N ECS V ++ Sbjct: 4769 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4804 Score = 44.7 bits (104), Expect = 9e-04 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386 P P G P D+ S+++L W +DGGS + Y +E W T Sbjct: 12692 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12751 Query: 1387 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438 + L +Y+FR A S PS+ S+ T+ + P+ ++ V+ Sbjct: 12752 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12803 Score = 44.3 bits (103), Expect = 0.001 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99 L +K G T +F +RG P P W +G I + + ++ FS L I Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11079 Query: 100 DRGKYTCEATNGSGARQVTVELTV 123 D G+Y +N +G++ V V LTV Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV 11103 Score = 44.3 bits (103), Expect = 0.001 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%) Query: 601 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 +EK S + +PV A P F + V+ G + + V G P P V W + Sbjct: 15628 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15687 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718 ++++ + E L I++ ED G Y + NSAGE + T V+ + +P Sbjct: 15688 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15747 Query: 719 TQP 721 T P Sbjct: 15748 TGP 15750 Score = 43.9 bits (102), Expect = 0.002 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V+V+ G R + GRP P+VTW K + + V + M L I +DD G Sbjct: 12119 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12177 Query: 230 VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279 Y+ +VN +G+ ++ + + + S V +T +D +VT+ I Sbjct: 12178 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12237 Query: 280 SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311 ++ + D A P P A++ Sbjct: 12238 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12297 Query: 312 --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365 S+P PPR+ ++ + T P L+ K IT QP R V+ Sbjct: 12298 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12357 Query: 366 ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413 G++ K R A + P G V +A + +P Sbjct: 12358 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12402 Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 PK P+ +K + ++ V G P P W +G + V++ S L Sbjct: 12403 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12460 Query: 474 LLKARTRDSGTYSCTASNAQG 494 + +DSG YS TA N+ G Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481 Score = 43.9 bits (102), Expect = 0.002 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L Sbjct: 12402 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12460 Query: 220 IHGVNQDDVGVYTCLVVNGSG 240 I V + D G Y+ N SG Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%) Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60 VK V ++ +SK S +V P R D P + F+ ++EG +++G P Sbjct: 9594 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9647 Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 P +TW + N +P+ T + ++D T +LVI D G YT A N Sbjct: 9648 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9703 Query: 111 GSGARQVTVELTVEG 125 G + L V G Sbjct: 9704 NLGTASKEMRLNVLG 9718 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 1810 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 + +KT++++EV E A F+C++ + P +W K+ I S F+I + LII Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 + +D A+YT N AT T I+ T + EE++ Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938 Score = 43.1 bits (100), Expect = 0.003 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1870 +EV EG+ KI+G P P + WFK +++ + YD D C+L+I Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9687 Query: 1871 DVCGDDDAKYTCKAVNSLGEAT 1892 D YT AVN+LG A+ Sbjct: 9688 QSRRSDTGLYTITAVNNLGTAS 9709 Score = 43.1 bits (100), Expect = 0.003 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287 Y N SG A SA +++ LD + K TN V KE IS E+ LD+ Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11531 Score = 43.1 bits (100), Expect = 0.003 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V E K + P + + G R + + G P P W K + + S H + Sbjct: 12391 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + D + LII DV D Y+ A NS G T +++V Sbjct: 12451 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491 Score = 43.1 bits (100), Expect = 0.003 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 1782 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1838 NA + SE S + A E P + P + TI V G + + D I G P P Sbjct: 16020 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16076 Query: 1839 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 + W K DQ + + +I D SL + D D Y KA N GE + T + Sbjct: 16077 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135 Query: 1899 V 1899 V Sbjct: 16136 V 16136 Score = 43.1 bits (100), Expect = 0.003 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390 P PP S + S+TL W DGGS + Y IE + + W + Sbjct: 19486 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19544 Query: 1391 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421 V+ L EY++RV A N G S PS+ S L Sbjct: 19545 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19577 Score = 42.7 bits (99), Expect = 0.003 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%) Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150 +G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 +++++ ED+G Y V Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293 Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270 + G ++ +K KP P I+Q DQKV G+ V+L KV+ + + Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341 Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401 Query: 1331 PDP 1333 P Sbjct: 2402 ITP 2404 Score = 42.7 bits (99), Expect = 0.003 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%) Query: 1811 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1864 F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D Sbjct: 4620 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +I DV D +YTC E T TA+L+VE + Sbjct: 4678 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713 Score = 42.7 bits (99), Expect = 0.003 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%) Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167 + + TV G Q + V++K S P+ T P + PKF Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17137 Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227 +VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D Sbjct: 17138 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17195 Query: 228 VGVYTCLVVNGSGKASMSAELSI 250 G Y N +G S + + Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKV 17218 Score = 42.4 bits (98), Expect = 0.004 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%) Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107 +KS K +++ K + + +N + H G + + T+ A F++ ++D+ Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021 Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167 V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080 Query: 1168 YKCVAKNDAGQAE 1180 Y VA + A+ Sbjct: 3081 YTVVAGGNVSTAK 3093 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231 +K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10790 Query: 232 TCLVVNGSGKASMSAELSI 250 + V N +G ++S ++ + Sbjct: 10791 SLTVENPAGSKTVSVKVLV 10809 Score = 42.4 bits (98), Expect = 0.004 Identities = 21/72 (29%), Positives = 34/72 (47%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++++ G R + GRP P++TW K NV L+ + + + L VN+ D G Sbjct: 13206 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13265 Query: 230 VYTCLVVNGSGK 241 Y + N GK Sbjct: 13266 KYILTLENSCGK 13277 Score = 42.4 bits (98), Expect = 0.004 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + + V G P P V W +++++ +FE T L I E D+G Y Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642 Query: 697 AWNSAGEVRTQAVLTVQ 713 A N GEV V+T+Q Sbjct: 14643 ARNIVGEVGD--VITIQ 14657 Score = 42.4 bits (98), Expect = 0.004 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576 KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+ Sbjct: 16053 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16112 Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633 D G Y A+N G+ S VTV+ K R P P P+ + G++ K Sbjct: 16113 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16159 Query: 634 -----VMDGSQVTMTVQVSGNPPPEVIW 656 + DG + V ++W Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVW 16187 Score = 42.4 bits (98), Expect = 0.004 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 +P VKP FS V G + + I G P P + W KD ++++ + D Sbjct: 16732 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16786 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898 +L I + DD +Y N +G+ T + E++ Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16821 Score = 42.4 bits (98), Expect = 0.004 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 736 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795 + + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+ Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 18971 Query: 796 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 + N G + +++++ + P + SC+ + Sbjct: 18972 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19007 Score = 42.0 bits (97), Expect = 0.006 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158 F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I Sbjct: 5790 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5847 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 PED Y C DA + SC + V Sbjct: 5848 DCTPEDIKTYTC----DAKDFKTSCNLNV 5872 Score = 42.0 bits (97), Expect = 0.006 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88 L E F N+ + E T K V P +V W++ + I GR+ + R Sbjct: 5962 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6020 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 LVI H ED G Y C + +V V Sbjct: 6021 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6051 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 E +F +K + + EG+ F C I+ P V W + + L+ + Sbjct: 6052 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6101 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 V +VL + D+G Y +V G A +A L++ Sbjct: 6102 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6139 Score = 42.0 bits (97), Expect = 0.006 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578 G+ + V G P+P+I W N I+ + EL I A+ ED Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 8975 Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKS 605 GTYT A N LG V + V V+++ S Sbjct: 8976 GTYTVTASNRLGSVFRNVHVEVYDRPS 9002 Score = 42.0 bits (97), Expect = 0.006 Identities = 26/93 (27%), Positives = 39/93 (41%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P+ + ++ + L V G+ V + G P P W +G+EI+ E + E Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11070 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 L I+ DTG Y N+AG LTV Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103 Score = 42.0 bits (97), Expect = 0.006 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V G P P+V W G ++G +++ + +L + + DSG YS T N G+ Sbjct: 12133 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12190 Query: 497 SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 + ++V L V +V + V +G V V R TW Sbjct: 12191 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12248 Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609 + T E H+ + +P + + A N G V K S Sbjct: 12249 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12296 Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666 + L S+P P + ++ +++T PP L +G + Sbjct: 12297 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12338 Query: 667 ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716 E+ R T++S+ ++++ TG + A N+ G + V E Sbjct: 12339 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12397 Query: 717 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776 + P I P +T G+ + I + G P PT W + G+ + H V + + Sbjct: 12398 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12456 Query: 777 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820 L++K V +G Y + +N G + ++ +++ ++ P Sbjct: 12457 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12500 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T G +V + + G P PTV W +DG L K ++ ++ TL L V + Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866 Query: 790 GQYEILLKNRVGECSCQVSL 809 G Y I +N G S + L Sbjct: 12867 GDYTITAENSSGSKSATIKL 12886 Score = 42.0 bits (97), Expect = 0.006 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230 VV+ G R GRP P W K + L S R + + L + N++D G Sbjct: 21871 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 21928 Query: 231 YTCLVVNGSGKASMSAELSI 250 YT V N SG S++ + + Sbjct: 21929 YTLTVENNSGSKSITFTVKV 21948 Score = 42.0 bits (97), Expect = 0.006 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639 + LA+NA G +S + T + + EY AP K L G DL + GS Sbjct: 22517 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22567 Query: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699 + + V G P P++IW E+ E + G + + I+ D+G YT N Sbjct: 22568 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22627 Query: 700 SAGEVRTQAVLTVQEPHDGTQP 721 ++G T+AV + + D P Sbjct: 22628 ASG---TKAVSVMVKVLDSPGP 22646 Score = 42.0 bits (97), Expect = 0.006 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 T D ++ P E + G+ V ++ G + G+P+P++ W KG+ Sbjct: 22539 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22588 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255 L +VS+ I ++ D G YT V N SG ++S + + LDS Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22643 Score = 41.6 bits (96), Expect = 0.008 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98 +N+ + E TA FE V + P + W +NG I +F + ++G L+I Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899 Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134 ED +YT N + +TV E+TV EG K L Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959 Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168 V K+ GD F A + +++ E +F + Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019 Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 + V E + F C+++ P V W+K + LQ + R+ + ++ + L I D Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078 Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265 G YT + +G +A+L ++G D RS +E + Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111 Score = 41.6 bits (96), Expect = 0.008 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V + Q + CE++ + +V W +G V + G I L + A D+GT Sbjct: 4727 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4784 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544 Y+ T NA L CS ++V V + ++D V + C + P Sbjct: 4785 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 4838 Query: 545 ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 I W + +P + L I++A+PED Y E A +T Sbjct: 4839 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 4894 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 + E R+ E L P+ D+ + + + ++S P W Sbjct: 4895 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 4935 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 G ++ S + G + L + +V + G +A N+ T A+LTV+E Sbjct: 4936 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 4987 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 + F + VT + C + + V W + G + K + F+++ + L Sbjct: 4988 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5044 Query: 780 VLKKVQPWHAGQY 792 V+ Q G Y Sbjct: 5045 VINDSQFDDEGVY 5057 Score = 41.6 bits (96), Expect = 0.008 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6025 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1913 + +D Y C+ +S + EL E + + + EGE+ E Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073 Score = 41.6 bits (96), Expect = 0.008 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%) Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64 A+ ISK S S P + + E P + P+ + + G T + E V G P P + Sbjct: 17103 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17160 Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 W R + I R C I+ T L++ D G+Y A+N +G++ V + Sbjct: 17161 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17216 Query: 122 TV 123 V Sbjct: 17217 KV 17218 Score = 41.6 bits (96), Expect = 0.008 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 ++VK G + GRP P V W K + L+ A V ++ L I N++D G Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19756 Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274 YT + N AS++ L ++ LD+ T T DV KE Sbjct: 19757 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19795 Score = 41.6 bits (96), Expect = 0.008 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 +K ++++ + V G P P V WF +G + ++ ++E+ + GS L + A G Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21531 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 Y+ A NA G ++V+ V P Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21561 Score = 41.6 bits (96), Expect = 0.008 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1864 + P D+ + EG C G P PEV W + I +E F I+ + D Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 26888 Query: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 +LII DV D YT N G + T + + ++ Sbjct: 26889 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926 Score = 41.2 bits (95), Expect = 0.010 Identities = 24/96 (25%), Positives = 43/96 (44%) Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217 +C P + ++V EG+ P P V+W K ++ S R+++ + Sbjct: 7887 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 7946 Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253 LE+ + D G+YT + N G A+ S + + GL Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982 Score = 41.2 bits (95), Expect = 0.010 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570 P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L + Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949 Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTV 600 ++ D G YT EN LG + S V V Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKV 7979 Score = 41.2 bits (95), Expect = 0.010 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454 VSK + P + QR P + K + EV+E V ++ G+P P + WF P Sbjct: 9602 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9658 Query: 455 RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506 ++ + V D + L C L ++R D+G Y+ TA N G S L V Sbjct: 9659 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718 Query: 507 LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557 V P F SV D + +G + + R TW+ ++ +P Sbjct: 9719 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9774 Query: 558 RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617 C + +L L + +A+N G + + + ++ + +P AP Sbjct: 9775 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 9823 Query: 618 SKPT 621 KPT Sbjct: 9824 DKPT 9827 Score = 41.2 bits (95), Expect = 0.010 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K I L V G+ RF I G P P W D I+ H+ ++ D + L I + Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D +Y N+ G T L V Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTV 11103 Score = 41.2 bits (95), Expect = 0.010 Identities = 23/80 (28%), Positives = 36/80 (45%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G++ ++ I G P P V W +DGK L + E+ TLV+K Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279 Query: 790 GQYEILLKNRVGECSCQVSL 809 GQY + L N G S +++ Sbjct: 18280 GQYILKLSNVGGTKSIPITV 18299 Score = 41.2 bits (95), Expect = 0.010 Identities = 26/85 (30%), Positives = 34/85 (40%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L+L V P IIWT K L + + L G + I+ D G Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y KN +G S V V D+P Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDSP 22644 Score = 40.8 bits (94), Expect = 0.013 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Query: 604 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233 Query: 663 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 +++ + E + ++ I + DTGTY EA N G R AV+ V Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7281 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D Sbjct: 7198 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7256 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y +AVN G AT E+ V Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNV 7283 Score = 40.8 bits (94), Expect = 0.013 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389 P PP + I ++ L W DGGS + +Y +E D K W+ + T + T Sbjct: 7587 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7645 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414 V L Y FRV A N G S+ Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSD 7670 Score = 40.8 bits (94), Expect = 0.013 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P IL P + IK G + E V G P P W + + + + + L+ Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12460 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I V +D G Y+ A N SG +++ V Sbjct: 12461 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491 Score = 40.8 bits (94), Expect = 0.013 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%) Query: 484 TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542 ++ +A N +G +S L V +A + + P+F + V+ G+D + G P Sbjct: 15621 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15679 Query: 543 PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 P +TW + P+ Q R E+ + L I+DA ED G Y N+ G+ + V Sbjct: 15680 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15739 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPI 624 V +K P PT P+ Sbjct: 15740 VLDK-------------PGPPTGPV 15751 Score = 40.8 bits (94), Expect = 0.013 Identities = 20/81 (24%), Positives = 39/81 (48%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y N +G+ S++ + + Sbjct: 16116 NYILKAKNVAGERSVTVNVKV 16136 Score = 40.8 bits (94), Expect = 0.013 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 ++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+ Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16802 Query: 104 YTCEATNGSGARQVTVEL 121 Y N G + ++E+ Sbjct: 16803 YGITVANVVGQKTASIEI 16820 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 ++P + G + + + G P P + W KD + ++++ ++ + + Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17871 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + DD KYT A NS G AT +IV Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904 Score = 40.8 bits (94), Expect = 0.013 Identities = 23/74 (31%), Positives = 33/74 (44%) Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698 Q+ + V G P V W +G ++E+ + T SL I+E ED GTY Sbjct: 18914 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 18973 Query: 699 NSAGEVRTQAVLTV 712 NSAG + + V Sbjct: 18974 NSAGSITVPITIIV 18987 Score = 40.8 bits (94), Expect = 0.013 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 711 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757 +V EP + T P + PR + G+ + I+ IAG P P + W +D Sbjct: 19270 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19329 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808 G + ++ E++ ++ L +K GQY + LKN G S V+ Sbjct: 19330 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19379 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5847 Query: 1871 DVCGDDDAKYTCKA 1884 D +D YTC A Sbjct: 5848 DCTPEDIKTYTCDA 5861 Score = 40.4 bits (93), Expect = 0.017 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + ++ G T + RV+G PEP +TW + G+ + R L + L I D Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11479 Query: 102 GKYTCEATNGSGARQ 116 GKY A N SG Q Sbjct: 11480 GKYIISAKNSSGHAQ 11494 Score = 40.4 bits (93), Expect = 0.017 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V+ QT++ V G P+P++ W EG + R E +++ +D L + +A D G Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11481 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y +A N+ G S + V + L V V ++ + + G + V Sbjct: 11482 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11541 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596 +P Q S + V + I+ + L + + AEN +G Sbjct: 11542 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11585 Query: 597 WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650 T+ K +L + P +P P +L + D + + ++ G Sbjct: 11586 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11633 Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705 P + H ++ S+D+ +G+ + + + + N GE V+ Sbjct: 11634 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11691 Query: 706 TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763 T+ V+ + D +P K V T G ++ + + G PFP V W +D A Sbjct: 11692 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11748 Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 + ++ D L K + G+Y + N G Sbjct: 11749 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11786 Score = 40.4 bits (93), Expect = 0.017 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 VK V V G P P V+W +GT ++ EG I++ L L +DSG Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 12868 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y+ TA N+ G S + L+V Sbjct: 12869 YTITAENSSGSKSATIKLKV 12888 Score = 40.4 bits (93), Expect = 0.017 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%) Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 S++ G ++ +++ R+++ P F + V G+ F L+ V G P+P I WL Sbjct: 17111 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17164 Query: 550 NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605 + I+ + + CE A L ++DA+ D G Y A N G S V V ++ Sbjct: 17165 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17221 Query: 606 SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633 P P P+ + G++ K Sbjct: 17222 -----------PGPPEGPVQVTGVTSEK 17238 Score = 40.0 bits (92), Expect = 0.022 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%) Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72 DP+ V L E P IL R IK G T + ++G P P+VTW + + Sbjct: 10702 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10761 Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + R +D G+ + +A H ED G Y+ N +G++ V+V++ V Sbjct: 10762 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10809 Score = 40.0 bits (92), Expect = 0.022 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482 VK T++ V G P PEVAW + T + R +++ A S L KA+ D Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11774 Query: 483 GTYSCTASNAQGQLSCSWTLQV 504 G Y TA+N G T+ V Sbjct: 11775 GKYVVTATNTAGSFVAYATVNV 11796 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%) Query: 598 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656 V V+EK S +P VA P S V G + + V +SG P P + W Sbjct: 16707 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16766 Query: 657 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715 +G ++++ + +L I+E +D G Y N G+ + ++T+ +P Sbjct: 16767 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16826 Score = 40.0 bits (92), Expect = 0.022 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575 KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D + Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y N G S V V ++ P P P+ + G++ Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18318 Score = 40.0 bits (92), Expect = 0.022 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%) Query: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480 Q+ V+ +++ G P P W P +++ L + Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 21924 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y+ T N G S ++T++V + +V ++++ D +++G + Sbjct: 21925 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 21984 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 V R +W Q C + +++ LAE Sbjct: 21985 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22024 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 SA V+E E P+ ++ AP L V+D S+ + + Sbjct: 22025 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22068 Query: 654 VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700 WL H+G Q+ DF E T Q + ++ + + + +A N Sbjct: 22069 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22126 Query: 701 AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756 AG + + ++EP + T + +T G I I+G P P V W Sbjct: 22127 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22186 Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 + L K+T + +D TL +K +G+Y + L+N G + V++++ Sbjct: 22187 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22245 Query: 817 RAL-PRGREPASCED-LCGGGVGADGGGSD 844 P S E + G DGGG++ Sbjct: 22246 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103 G AKF ++ P + W + G+ I + C IR + SL I D G+ Sbjct: 4351 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4406 Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150 YTC+A+N G+ T LTV G+ V K L +R P E Sbjct: 4407 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4449 Score = 39.7 bits (91), Expect = 0.029 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Query: 1788 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1841 S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V Sbjct: 5494 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5552 Query: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 WFKD + I+ S++ I D LI+ D +YTC Sbjct: 5553 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5592 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73 PSR + ++ EAP L + L +K G + V G PEP++TW + + Sbjct: 7175 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7234 Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 R ++ + ++ I D G Y EA N G VE+ V Sbjct: 7235 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283 Score = 39.7 bits (91), Expect = 0.029 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V E + + +P P V+W +G V+ + + + D S +L + K+ D+G Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 7959 Query: 485 YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537 Y+ T N G + S ++V + + ++ S + + +G +L + Sbjct: 7960 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8019 Query: 538 RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597 R T++ P+ + V +D +P + A N +G Sbjct: 8020 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8063 Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657 E PV P P D++V + + MT+ + PP L Sbjct: 8064 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8107 Query: 658 HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712 ++G +G + C + + P TYT + E VR + + Sbjct: 8108 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8165 Query: 713 QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757 EP T P P S+ G + + +I+G P+PT+ W++D Sbjct: 8166 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8219 Score = 39.7 bits (91), Expect = 0.029 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 L I+ G GR G P+P+V+W ++ + R + T +L D Sbjct: 10331 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10389 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161 GKY N +G+R+ ++ V + G PV + F + W Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10441 Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221 +K+ ++++ ++G+ V + + + +VS + + IH Sbjct: 10442 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490 Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273 N G+ LV + SM A+ + D+ ++ V E ++ D K Sbjct: 10491 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10543 Query: 274 EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317 +TN I ++ + S A +K+ C R + P PP Sbjct: 10544 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10603 Query: 318 RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373 + +K K SP P+ S +T Q R + G V G+E R Sbjct: 10604 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10663 Query: 374 PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420 A P + P T+ G +D K + G+ D A K +P Sbjct: 10664 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10723 Query: 421 -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 + Q +K T++ + G+P P+V W E + I+V GS L + Sbjct: 10724 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10780 Query: 476 KARTRDSGTYSCTASNAQGQLSCS 499 A D G YS T N G + S Sbjct: 10781 NAAHEDGGIYSLTVENPAGSKTVS 10804 Score = 39.7 bits (91), Expect = 0.029 Identities = 23/81 (28%), Positives = 34/81 (41%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 +VVK G RF I G P P W ++ +V N VL I + D G Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11082 Query: 230 VYTCLVVNGSGKASMSAELSI 250 Y V N +G +++ L++ Sbjct: 11083 EYQITVSNAAGSKTVAVHLTV 11103 Score = 39.7 bits (91), Expect = 0.029 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 +++ A + + + P V EAP L + + ++ G +A+ +G P Sbjct: 17496 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17555 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P++TW R T + ++ G+ T L I D GKY + N SG++ V Sbjct: 17556 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17612 Query: 121 LTV 123 + V Sbjct: 17613 VKV 17615 Score = 39.7 bits (91), Expect = 0.029 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166 V + G L L VS PP I W+ G L + I ++ SL + ++K D G Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23016 Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191 Y A+N +G+ + V V D P Sbjct: 23017 KYTIEAENQSGKKSATVLVKVYDTP 23041 Score = 39.3 bits (90), Expect = 0.037 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779 P F +SV G + I+G P P V W RDG+ + T ++ ++ L Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839 + V ++G+Y + N G+ + L+++ +A P + L + Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116 Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893 G R G P + DG +++ L ++ E Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174 Query: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953 ++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231 Query: 954 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005 RS+ + G + +P K PP P P RS + K +L + S Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287 Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032 S P+ + + P PV + PA Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857 E V + P KP D+ V+EG P P V W KD + ++ S + Sbjct: 7879 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 7938 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 D + L + D YT N LG AT + + V Sbjct: 7939 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%) Query: 518 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575 SV ++ G+ + V G PVP W + R + +EL I+DAL Sbjct: 8612 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8671 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 +DHG Y A N+ G +A V V + +L + P + L SD + Sbjct: 8672 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8726 Query: 636 DGSQVT 641 GS++T Sbjct: 8727 GGSEIT 8732 Score = 39.3 bits (90), Expect = 0.037 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785 G + I I G P P W DGKA KD H E +N V +++ + + Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9385 Query: 786 PWHAGQYEILLKNRVGE--CSCQVSLM 810 H G+Y I KN+ G+ +C+V +M Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVM 9412 Score = 39.3 bits (90), Expect = 0.037 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 668 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725 D HFE G H + + G ++ E S G + + V P P + Sbjct: 15998 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16054 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785 ++ G+S + I G P PT+ W++ + L +T E+ + +L +K Sbjct: 16055 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16110 Query: 786 PWHAGQYEILLKNRVGECSCQVSL 809 +G Y + KN GE S V++ Sbjct: 16111 RVDSGNYILKAKNVAGERSVTVNV 16134 Score = 38.9 bits (89), Expect = 0.049 Identities = 21/81 (25%), Positives = 35/81 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + V G + + +V G P P++ W G + + Q + L I+E D G Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480 Query: 692 TYTCEAWNSAGEVRTQAVLTV 712 Y A NS+G + A++ V Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV 11501 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 SV A G+ V + G P PTV W +D K L D + + + L + +V Sbjct: 20783 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20841 Query: 789 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831 G+Y + ++N VGE SS ++ PA+C+ L Sbjct: 20842 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 20875 Score = 38.9 bits (89), Expect = 0.049 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT + Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 +NA+ +++ V L P PSKP PI Sbjct: 21141 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21167 Score = 38.5 bits (88), Expect = 0.064 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%) Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 G E+ T + PAP P PP ++ ++ V GESV L ++G T TW + Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 QI+ S ++ ++L I A E G +T N+ G+ L V Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986 Score = 38.5 bits (88), Expect = 0.064 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 614 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 PV ++P P + + +++M G + + V+G P P +W E+ + + Sbjct: 8595 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8653 Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 + GT+ L I++ +D G Y A NS G Sbjct: 8654 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8686 Score = 38.5 bits (88), Expect = 0.064 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98 L +K G T + E VRG P P+V W ++ +T R +D + FSL Sbjct: 11714 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11771 Query: 99 EDRGKYTCEATNGSGA 114 D GKY ATN +G+ Sbjct: 11772 SDGGKYVVTATNTAGS 11787 Score = 38.5 bits (88), Expect = 0.064 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%) Query: 403 IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462 IP EG+ D+ K + ++ T++ V G P P++ W +R + G ++ Sbjct: 13192 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13244 Query: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515 + +L D+G Y T N+ G+ + ++V + V E++ Sbjct: 13245 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13304 Query: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575 + V + +I+G ++ V+ R +W + T E + + Sbjct: 13305 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13355 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635 + AEN G + + +R + V S+ P+ DLKV Sbjct: 13356 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13396 Query: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691 S+ + ++ G P G+ I DF E+ Q SL +Q + T Sbjct: 13397 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13450 Query: 692 ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744 T+ A N GE T + +TV D P K A + + I Sbjct: 13451 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13509 Query: 745 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 G P P+V W + L DT V + TL++ Q AG+Y I LKN G Sbjct: 13510 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568 Query: 805 CQVSL 809 +S+ Sbjct: 13569 GTISI 13573 Score = 38.5 bits (88), Expect = 0.064 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 PAF L + G K + G P P VTWH++ P+ R + L Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15709 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I ED G Y + TN +G T+ + V G + + D + Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15764 Query: 153 PSIWGECPPKF 163 WG PPK+ Sbjct: 15765 ---WG--PPKY 15770 Score = 38.5 bits (88), Expect = 0.064 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 RD VV G R + + G P P + W + D+ I ES +I + D LI+ D Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17193 Query: 1875 DDDAKYTCKAVNSLG 1889 D +Y +A N G Sbjct: 17194 IDGGQYILRASNVAG 17208 Score = 38.5 bits (88), Expect = 0.064 Identities = 22/83 (26%), Positives = 37/83 (44%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + K G I+GRP P+VTW + L+ + RVS++ L + + D G Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y + N +G + S + + G Sbjct: 22220 RYFLTLENTAGVKTFSVTVVVIG 22242 Score = 38.1 bits (87), Expect = 0.083 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%) Query: 541 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 PV W+ +N +PI+ + E GV +P+ A NA+G Sbjct: 7828 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7871 Query: 600 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658 + S SE ++ P KPT + D+ V++G ++++ V P P V W Sbjct: 7872 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925 Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717 +G E++ S+ + L + + D G YT N G V + P Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 7983 Query: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771 P K +T S SC + +P P +H++ + + + T + V+ Sbjct: 7984 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8033 Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 E+ + +K + P + + N+VG Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8063 Score = 37.7 bits (86), Expect = 0.11 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%) Query: 620 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672 PT + L D +KV G V + V+G P P++ W N I++ D Sbjct: 8898 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 8957 Query: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704 + + L I + ED GTYT A N G V Sbjct: 8958 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 8989 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/73 (27%), Positives = 33/73 (45%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V++K G+ R ++GRP P + W K L+ +A++ + + L + D G Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033 Query: 230 VYTCLVVNGSGKA 242 YT N G A Sbjct: 15034 AYTLTATNPGGFA 15046 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86 +AP L P+ + + G T E +RG P P V W ++G+ + + R + I+ Sbjct: 18206 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18265 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 T +LV+ D G+Y + +N G + + + + V Sbjct: 18266 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301 Score = 37.7 bits (86), Expect = 0.11 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 617 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663 PS+ T PI ++ + D+K D G + + ++G P P + W +G EI Sbjct: 19274 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19333 Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702 +E L +++ DTG Y N AG Sbjct: 19334 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19372 Score = 37.7 bits (86), Expect = 0.11 Identities = 20/83 (24%), Positives = 38/83 (45%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168 + G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532 Query: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191 AKN +G A+ +V V D P Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTP 21555 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1876 ++++ G R + G P P VW K++ + + R + D G S LII D D Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8673 Query: 1877 DAKYTCKAVNSLGEATCTAELIV 1899 +Y A NS G A + V Sbjct: 8674 HGRYVITATNSCGSKFAAARVEV 8696 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 +T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+ Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11479 Query: 790 GQYEILLKNRVG 801 G+Y I KN G Sbjct: 11480 GKYIISAKNSSG 11491 Score = 37.4 bits (85), Expect = 0.14 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584 G + L +V G P+P ++W +G +P + + + + L + +D G YT Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872 Query: 585 AENALGQVSCSAWVTVHEK 603 AEN+ G S + + V +K Sbjct: 12873 AENSSGSKSATIKLKVLDK 12891 Score = 37.4 bits (85), Expect = 0.14 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%) Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78 VDP R+ P + + + G + K + + G P P + W + Q +++ R Sbjct: 16041 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16092 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + T SL + D G Y +A N +G R VTV + V G V+S Sbjct: 16093 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16151 Query: 139 TLGDR 143 ++ Sbjct: 16152 VTAEK 16156 Score = 37.4 bits (85), Expect = 0.14 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480 V+ + + G P PE+ W R+EG +V + G +Y L + Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17591 Query: 481 DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 D+G Y N+ G S T++V + LAV EV + ++ + +I+G V Sbjct: 17592 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17651 Query: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 + R YA + + +++ + +AEN G Sbjct: 17652 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17699 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 V V + + +E P P K T + D SQ + ++ PE Sbjct: 17700 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17740 Query: 654 VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703 H+G + +GT+ +C V +G + +A+N G+ Sbjct: 17741 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17796 Query: 704 VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762 + + D T QP + + G+ + I + G P P + W++DG+ L Sbjct: 17797 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 17855 Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 K T V + L +K+ G+Y + N G + +S+++ Sbjct: 17856 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904 Score = 37.4 bits (85), Expect = 0.14 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%) Query: 1791 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1847 D S + +A+E+ +P F S+ + L V G++ G P P V+W K D Sbjct: 19670 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19728 Query: 1848 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903 +R + D SL I + +D KYT N L A+ T L+V+ ++ Sbjct: 19729 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19779 Score = 37.4 bits (85), Expect = 0.14 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97 P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ + Sbjct: 19985 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20043 Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137 D G+Y A N SG + + + V G V+S Sbjct: 20044 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y + Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21534 Query: 795 LLKNRVGECSCQVSLMLQNSSARAL 819 KN G ++ + +Q++ + + Sbjct: 21535 EAKNASGSAKAEIKVKVQDTPGKVV 21559 Score = 37.0 bits (84), Expect = 0.19 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%) Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137 + H G + + P + V V EG+ +C+V+ P + W LNG+ Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834 Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195 ++ +K + +G + + I D G K A+N G E ++ + S Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893 Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 +APE RP+ + + + +P T K + + + +KV ES Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949 Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290 EL K + IT +K RK+ + E + K +E Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009 Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340 G K+TI L+ E + + +G A + VV KPDP Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063 Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400 WY + IE D W E C ++D+ + Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101 Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451 V+AIN+ G + Q +L T ++ ++ KD + + + EP V + Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161 Query: 1452 VTINTEQKVSDFY 1464 E D Y Sbjct: 2162 YKDGMEVHEGDKY 2174 Score = 37.0 bits (84), Expect = 0.19 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%) Query: 935 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994 P+ V E + K+ Q+ DFRSVL + P P+ P+F GK + + Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916 Query: 995 NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054 +T K V K + + K E + + + T + A Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967 Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101 LKS K+E +++ + H T+ EK++ E + T P FK Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027 Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152 +++Q V +G + +V P W NG K ++ + E ++ Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087 Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178 C + I ED A N AG+ Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + VSG PPP V W N NE ++ E S+ I+ G Y+ Sbjct: 10042 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10099 Query: 697 AWNSAGEVRTQAVLTV 712 A N AGE + ++ V Sbjct: 10100 AKNEAGERKKTIIVDV 10115 Score = 37.0 bits (84), Expect = 0.19 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1870 T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I Sbjct: 11416 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11472 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTA 1895 + D KY A NS G A +A Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSA 11497 Score = 37.0 bits (84), Expect = 0.19 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 1800 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1853 V E+ VK K + DL+ V G R + + G P PEV W KD + +R Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749 Query: 1854 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 ++ D + S ++ D KY A N+ G A + V Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796 Score = 37.0 bits (84), Expect = 0.19 Identities = 22/92 (23%), Positives = 40/92 (43%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G ++ + V G P P W +E+ S + + L I++V +D+G Sbjct: 12411 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12470 Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723 Y+ A NS+G + + V + QP F Sbjct: 12471 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 + + G + R I+G P PEV W K D IR++ + SL++ +V D Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16511 Query: 1878 AKYTCKAVNSLG 1889 KYT NS G Sbjct: 16512 GKYTLTLENSSG 16523 Score = 37.0 bits (84), Expect = 0.19 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 1809 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1865 P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20431 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 S++I D + Y K N++G A+ T Sbjct: 20432 SILIKDADRLNSGCYELKLRNAMGSASAT 20460 Score = 37.0 bits (84), Expect = 0.19 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 V + G + I+G+P P + W K + LQ +A V V + + I ++ + G Sbjct: 20385 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20444 Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254 Y + N G A SA + +Q LD Sbjct: 20445 CYELKLRNAMGSA--SATIRVQILD 20467 Score = 36.6 bits (83), Expect = 0.24 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%) Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202 RF A E R + PK T +VV G+ P+ + W K N PL Sbjct: 6485 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6544 Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + +E+ ++LE + D G Y ++ N GKA L + Sbjct: 6545 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6589 Score = 36.6 bits (83), Expect = 0.24 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223 V+EG KI G P P +TW K P +P + V + N + V L I Sbjct: 9631 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9689 Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252 + D G+YT VN G AS L++ G Sbjct: 9690 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9718 Score = 36.6 bits (83), Expect = 0.24 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586 G L ++G P P++TW + AR ++L I++A ED G Y+ E Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10795 Query: 587 NALGQVSCSAWVTVHEK 603 N G + S V V +K Sbjct: 10796 NPAGSKTVSVKVLVLDK 10812 Score = 36.6 bits (83), Expect = 0.24 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%) Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643 A+N G +S + T + K EY P PT L + G + + Sbjct: 13853 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 13903 Query: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703 + + G P P+ W G +I+ S+ T L I+ +D G YT A N G Sbjct: 13904 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 13963 Query: 704 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734 +TV + P IS + A+L Sbjct: 13964 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 13994 Score = 36.6 bits (83), Expect = 0.24 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 634 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693 V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050 Query: 694 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725 A NS+G + ++ + P T P IS Sbjct: 20051 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083 Score = 36.6 bits (83), Expect = 0.24 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 1794 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1850 +AF + +E P ++P T +++ GS D I G P P+V W ++ ++ Sbjct: 22134 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22192 Query: 1851 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 E+ I +D +L + D D +Y N+ G T + ++V Sbjct: 22193 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240 Score = 36.2 bits (82), Expect = 0.32 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128 NC+ G D N K S P + L+DV V G+ C++S + Sbjct: 5670 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5728 Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174 + W L GK L+ + ++ EG + ++++ ED G + AK+ Sbjct: 5729 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5774 Score = 36.2 bits (82), Expect = 0.32 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%) Query: 438 SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 SG PKP+V+WF + V ++ + + L +KA+ DSG Y N+ G Sbjct: 10346 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10404 Query: 498 CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526 + V V P SF V KD VI Sbjct: 10405 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10434 Score = 36.2 bits (82), Expect = 0.32 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 ++ + G++ + + G P PT+ WLR K + +++ E+ + L++K Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17195 Query: 789 AGQYEILLKNRVGECSCQVSL 809 GQY + N G S V++ Sbjct: 17196 GGQYILRASNVAGSKSFPVNV 17216 Score = 35.8 bits (81), Expect = 0.41 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P T L V +EG + + IT + V W N + + + L I Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300 Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250 VN +D G Y C +N SGK + SA+L++ Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331 Score = 35.8 bits (81), Expect = 0.41 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%) Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147 T S ++ + E ++ +A N G + ++ L V + D P Sbjct: 8854 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 8898 Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204 ++ R S+ G+ + VK G+ +TG P P++ W K ++ Sbjct: 8899 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 8948 Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260 + VS L I ++D G YT N G + + + S R+ Sbjct: 8949 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9008 Query: 261 VRETKA 266 V + KA Sbjct: 9009 VTDIKA 9014 Score = 35.8 bits (81), Expect = 0.41 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 735 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794 G +V I G P PT W DG + K H+ V + L +K G+Y+I Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086 Query: 795 LLKNRVGECSCQVSL 809 + N G + V L Sbjct: 11087 TVSNAAGSKTVAVHL 11101 Score = 35.8 bits (81), Expect = 0.41 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86 EAP +L P L IK G T + G P P+ +W + G+ I + Sbjct: 13877 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 13936 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + + +A + D G+YT ATN G + V++TV Sbjct: 13937 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 13972 Score = 35.8 bits (81), Expect = 0.41 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584 G + ++ V G P P +TW Q ++ + A L+I + + D G Y Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624 A N +G+V + VH+ P PT PI Sbjct: 14643 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14669 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103 I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16513 Query: 104 YTCEATNGSGARQVTVELTV 123 YT N SG + V + V Sbjct: 16514 YTLTLENSSGTKSAFVTVRV 16533 Score = 35.8 bits (81), Expect = 0.41 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P+ LP +K K + +G P+ V W ++GQ + R + + SL Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 18956 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 I +ED G Y +N +G+ +TV +T+ Sbjct: 18957 IKEASKEDVGTYELCVSNSAGS--ITVPITI 18985 Score = 35.8 bits (81), Expect = 0.41 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 1833 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 +G P P V W KD++++ + I+ + D + L I V +D KY N +GE Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855 Score = 35.8 bits (81), Expect = 0.41 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%) Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142 +T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + + Sbjct: 26818 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 26877 Query: 1143 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + L ++ I +D GLY N+ G + + + Sbjct: 26878 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923 Score = 35.4 bits (80), Expect = 0.54 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F + L ++ V+E + L C+VS P A +IW + + T + EG + I+ Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6026 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219 A ED G Y C R P S +D Sbjct: 6027 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6045 Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279 VK + + I P++ ++ GE E ++ + W + K ++ Sbjct: 6046 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6095 Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330 + V L + A + G Y ++V G+ +A +LTV++K Sbjct: 6096 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6142 Score = 35.4 bits (80), Expect = 0.54 Identities = 16/82 (19%), Positives = 37/82 (45%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 ++ ++ G+ + + +G+P+P+V+W K + R + LE + D Sbjct: 10330 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10389 Query: 229 GVYTCLVVNGSGKASMSAELSI 250 G Y +V N +G ++++ Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV 10411 Score = 35.4 bits (80), Expect = 0.54 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%) Query: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676 KP + L G+ L V G + + V G P PEV W + ++ S + R Sbjct: 11703 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11760 Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 + + D G Y A N+AG A + V Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796 Score = 35.4 bits (80), Expect = 0.54 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%) Query: 581 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640 + +A+NA G +S + T + K E LP P + + V G Sbjct: 17096 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17146 Query: 641 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700 + V G P P + WL EI+ES + + L +++ D G Y A N Sbjct: 17147 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17206 Query: 701 AG 702 AG Sbjct: 17207 AG 17208 Score = 35.4 bits (80), Expect = 0.54 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 + +K G K + G P P ++W ++G I R + T L + D Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19360 Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157 G+Y N +G R V V V G ++ ++ S P + I Sbjct: 19361 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19420 Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205 K T + EG++ SCK+T LKGN + +P Sbjct: 19421 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19473 Query: 206 RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 V++ + V LEI V ++ + + C S S + I+ + + Sbjct: 19474 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19531 Query: 260 FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314 +VR K D+R + T + E ++ + AA S S R P + P Sbjct: 19532 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19587 Query: 315 QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373 PP + K+ +S K + A P+ + + + + S G E Sbjct: 19588 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19647 Query: 374 PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430 A + R +G+ D S +++ +I E + + F ++ VK + Sbjct: 19648 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19706 Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490 G P P V W T +R + ++ + S L + A DSG Y+ T Sbjct: 19707 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19763 Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526 N S + ++V + V K+ AV+ Sbjct: 19764 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19799 Score = 35.4 bits (80), Expect = 0.54 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229 + V++G + R + I G+P P W K + A ++ SE + L I ++ D G Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23706 Query: 230 VYTCLVVNGSGKASMSAELSIQG 252 Y ++ N GK ++ ++ + G Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIG 23729 Score = 35.4 bits (80), Expect = 0.54 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1867 P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 25934 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 I D DD Y N GEA+ A L V Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D++V E A+F+C++ P W K Q I F++ D + S++I Sbjct: 5345 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5402 Query: 1871 DVCGDDDAKYTCKA 1884 +D+AKY +A Sbjct: 5403 SAAFEDEAKYMFEA 5416 Score = 35.0 bits (79), Expect = 0.70 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228 R+VV G + R ++G+P P VTW L A + + + V I + Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10093 Query: 229 GVYTCLVVNGSGK 241 GVY+ L N +G+ Sbjct: 10094 GVYSLLAKNEAGE 10106 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101 ++ G + VRG P P+VTW + G + G L+D LVI +D Sbjct: 12121 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12176 Query: 102 GKYTCEATNGSGARQVTVELTV 123 GKY+ N +G + V V + V Sbjct: 12177 GKYSLTLVNPAGEKAVFVNVRV 12198 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877 L V G+ D + G P P V W KD ++ + ++ + C+L + V D Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866 Query: 1878 AKYTCKAVNSLGEATCTAELIV 1899 YT A NS G + T +L V Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888 Score = 35.0 bits (79), Expect = 0.70 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%) Query: 615 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 VA AP + L+GL DL + + S + + + G P P V W + + Sbjct: 13475 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13534 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721 E +L + + D G YT N AG + T ++ V +P T P Sbjct: 13535 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13585 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%) Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201 D + AP + P+I K G +V + I G+P P+ +W K + Sbjct: 13874 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 13923 Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240 +PS ++ +L I + D G YT N G Sbjct: 13924 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962 Score = 35.0 bits (79), Expect = 0.70 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788 +V G ++ + I+G P P V RDG L K T F + T+ LK+ Sbjct: 19988 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20046 Query: 789 AGQYEILLKNRVGECSCQVSLML 811 AG+YEI N G +++++ Sbjct: 20047 AGRYEITAANSSGTTKAFINIVV 20069 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565 V+++ ++ V+K A G L+ + G P P I W + + +Q C + Sbjct: 20374 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20430 Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 A + I+DA + G Y NA+G S + V + +K Sbjct: 20431 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20468 Score = 34.7 bits (78), Expect = 0.92 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%) Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V P+ W G PV + + E+ G Y Y A N QG Sbjct: 7127 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7173 Query: 497 SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553 S T +++ + E F V L V G L +V G P P+ITW Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233 Query: 554 I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603 + Q R T E + + I D+ D GTY A N G+ + V V +K Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286 Score = 34.7 bits (78), Expect = 0.92 Identities = 16/67 (23%), Positives = 28/67 (41%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696 G + + G P P + W+ E+ + + SL +++ D+G Y + Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120 Query: 697 AWNSAGE 703 A N AGE Sbjct: 16121 AKNVAGE 16127 Score = 34.7 bits (78), Expect = 0.92 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%) Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451 +SK ++ P+ + + P+ P+ ++ V +T + +V G P P + W L G Sbjct: 17107 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17165 Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497 + E+ L + A D G Y ASN G S Sbjct: 17166 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17211 Score = 34.7 bits (78), Expect = 0.92 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ AT + ++G PEP+V W + +T + + +F+ LVI V D G Sbjct: 18622 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18677 Query: 103 KYTCEATNGSGARQVTVELTV 123 +Y N SG++ V + V Sbjct: 18678 RYNLTLENNSGSKTAFVNVRV 18698 Score = 34.7 bits (78), Expect = 0.92 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866 +KP V + D +G P V W KD Q+++E+ + + S Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 18954 Query: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 L I + +D Y NS G T +IV Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987 Score = 34.3 bits (77), Expect = 1.2 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 ++D V E F+C++ + WF+++++I +S + I +D +L I D Sbjct: 6149 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6206 Query: 1875 DDDAKYTCKAVNSLGE-ATCTAELIVE 1900 DD A Y N GE A LIVE Sbjct: 6207 DDQANYNVSLTNHRGENVKSAANLIVE 6233 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%) Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470 +A PK ++ Q V + + PK E WF E P+ + +I+ + S Sbjct: 6500 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6556 Query: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523 +L+A+ D G Y N G+ L+ V L V E S+ + Sbjct: 6557 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6615 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLL 549 + +G ++ V + R TW+L Sbjct: 6616 PLTDGGSKIIGYVVERRDIKRKTWVL 6641 Score = 34.3 bits (77), Expect = 1.2 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57 G+ L S +K +S DPS + PLT AF+ P +L K+G + Sbjct: 6862 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 6919 Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110 GYP P TW + + +G R + + LVI D+G YT + N Sbjct: 6920 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 6974 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225 G + VK G R + G+P P+V W K L S RV + + + + Sbjct: 11712 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11771 Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250 D G Y N +G A +++ Sbjct: 11772 SDGGKYVVTATNTAGSFVAYATVNV 11796 Score = 34.3 bits (77), Expect = 1.2 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%) Query: 1812 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1871 S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17586 Query: 1872 VCGDDDA-KYTCKAVNSLG 1889 C +DA KY K NS G Sbjct: 17587 NCDRNDAGKYILKLENSSG 17605 Score = 34.3 bits (77), Expect = 1.2 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%) Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77 P V + E P + L R + +++G + ++G P P W + GQ I+ Sbjct: 23625 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23682 Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126 R ++ T LVI D G Y N G + V +++ V GS Sbjct: 23683 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23730 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 + G + I ++G P PTV W + + L ++ + ++V+K Q H Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10093 Query: 790 GQYEILLKNRVGE 802 G Y +L KN GE Sbjct: 10094 GVYSLLAKNEAGE 10106 Score = 33.9 bits (76), Expect = 1.6 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%) Query: 537 VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593 +RG PVP W +G I ++ + + L I++ L D G Y NA G + Sbjct: 11037 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11096 Query: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653 + +TV + P PT PI ++D + MT +S PP + Sbjct: 11097 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11133 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882 G A R + + G P P + W KD + + + +I D + +L+ D D YT Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15037 Query: 1883 KAVNSLGEA 1891 A N G A Sbjct: 15038 TATNPGGFA 15046 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%) Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70 +P+ V P E +LPP + + I+ T + ++G P P+V W R+ Sbjct: 15344 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15401 Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 G L I T S L++ V+ D GKY N SG++ V + V Sbjct: 15402 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15451 Score = 33.9 bits (76), Expect = 1.6 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 + + G + + V + G P PEV W EI+++ T SL + V D+G Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16512 Query: 692 TYTCEAWNSAG 702 YT NS+G Sbjct: 16513 KYTLTLENSSG 16523 Score = 33.9 bits (76), Expect = 1.6 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%) Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75 +++ P V + +T E +P + ++ G E +G P+P ++W ++G P+ Sbjct: 21050 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21109 Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 F+ +L I +E GKYT N ++ V +TV Sbjct: 21110 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21154 Score = 33.9 bits (76), Expect = 1.6 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%) Query: 1796 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1845 + E++AE ++P I DLE+ + G++ R + G P P + W K Sbjct: 22931 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 22985 Query: 1846 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1894 Q I + ID E + LI+ V D KYT +A N G+ + T Sbjct: 22986 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23032 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F + D V EG A F C++ + VVWFK+D + SR I E L + Sbjct: 5079 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5136 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 +V DD ++ + + E + TA+L V Sbjct: 5137 EVTLDDISQIKAQ----VKELSSTAQLKV 5161 Score = 33.5 bits (75), Expect = 2.0 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+ Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5491 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCT 1894 D+ DD ++ +A+ EA T Sbjct: 5492 DLSIDDTSQIRVEAMGMSSEAKLT 5515 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/72 (27%), Positives = 32/72 (44%) Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244 TG P+P TW G+ L+ RV + + L I + D G+YT + N S Sbjct: 6922 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981 Query: 245 SAELSIQGLDSA 256 ++++ SA Sbjct: 6982 EIDVNVIARPSA 6993 Score = 33.5 bits (75), Expect = 2.0 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%) Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69 S IS+ ++ DP P L ++ + EG R P P V+WH++ Sbjct: 7875 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 7926 Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125 G+ + + R + V +V D G YT N G+ ++ + V G Sbjct: 7927 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 7981 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582 G L+ VRG P P + W + RS A ++ + A D G Y Sbjct: 11719 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11778 Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621 A N G A V V +K ++ ++ V+ + T Sbjct: 11779 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11817 Score = 33.5 bits (75), Expect = 2.0 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96 + L ++ G T + V+G P P++TW + + R LD I+ T F + V Sbjct: 13204 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13259 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 ++ D GKY N G ++ T+ + V Sbjct: 13260 NKYDAGKYILTLENSCGKKEYTIVVKV 13286 Score = 33.5 bits (75), Expect = 2.0 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%) Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60 VK V S S S DP E P F + + L +K GA+ RG P Sbjct: 19660 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19717 Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 P V W + + + R +D T SL I + D GKYT N A +T+ Sbjct: 19718 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19774 Query: 121 LTV 123 + V Sbjct: 19775 VKV 19777 Score = 33.5 bits (75), Expect = 2.0 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 517 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572 S + K V G F + RG PVP + W +P R+ + L I++ Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19749 Query: 573 ALPEDHGTYTCLAENALGQVSCSAWVTV 600 A D G YT +N L S + V V Sbjct: 19750 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19777 Score = 33.5 bits (75), Expect = 2.0 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691 L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19756 Query: 692 TYTCEAWN 699 YT N Sbjct: 19757 KYTLTIQN 19764 Score = 33.1 bits (74), Expect = 2.7 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%) Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61 G KL+ + +LSV+ ++ I R+L E FE + + Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514 Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121 V W+ + I ++ ++ + + L + + ++D GKYT A G + +L Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569 Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181 TV G +SK L D+ V E Q F Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594 Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241 C++ P + WL+ L + + + L I DD+G YT V Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653 Query: 242 ASMSAE 247 A + E Sbjct: 2654 AKLKVE 2659 Score = 33.1 bits (74), Expect = 2.7 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 1776 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1821 S T +++E + ++ + L+ +++ K VK PYF+ + D V Sbjct: 5119 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5178 Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E C++ D V WFKD + I S + I D L I D +Y Sbjct: 5179 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5235 Query: 1882 CKAVNSLGEATCTAE 1896 C +A T E Sbjct: 5236 CDCGTDKTKANVTVE 5250 Score = 33.1 bits (74), Expect = 2.7 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%) Query: 442 KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501 K EV W L V Q ++ + H L + + RD G Y A + + + Sbjct: 6442 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6498 Query: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561 + AP + +D V G+ + P W +P+ Sbjct: 6499 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6550 Query: 562 EAGVAELHIQDALPEDHGTYTCLAENALGQ 591 A I +A D G Y + +N G+ Sbjct: 6551 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6580 Score = 33.1 bits (74), Expect = 2.7 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160 + V G+ + + V+ P I W+ N + K T + +++E + +SI KA Sbjct: 8911 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 8970 Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 + ED+G Y A N G + V V D P+ Sbjct: 8971 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9002 Score = 33.1 bits (74), Expect = 2.7 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 1816 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875 R+ + G R I+G P P+V W K+D+ +ID G+ L I + + Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10785 Query: 1876 DDAKYTCKAVNSLGEATCTAELIV 1899 D Y+ N G T + +++V Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809 Score = 33.1 bits (74), Expect = 2.7 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575 +D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D + Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19357 Query: 576 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 D G Y +N G S + V +K P P P+ + GL+ Sbjct: 19358 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19399 Score = 33.1 bits (74), Expect = 2.7 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102 ++ GA+ + +G P P W + ++ D +FS L + + D G Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 21927 Query: 103 KYTCEATNGSGARQVTVELTV 123 KYT N SG++ +T + V Sbjct: 21928 KYTLTVENNSGSKSITFTVKV 21948 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 + D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+ Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373 Query: 1875 DDDAKYTCKAVNSLGEAT 1892 +D Y+ + +LG +T Sbjct: 2374 EDAGNYSF-TIPALGLST 2390 Score = 32.7 bits (73), Expect = 3.5 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163 G ++ + + P W +GK K K + L + + I + Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387 Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 G Y AKN AGQ +C+V V D P Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKVMDVP 9415 Score = 32.7 bits (73), Expect = 3.5 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1881 GS D + G P+P+++W K D+ + + Y G + + C D KYT Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22622 Query: 1882 CKAVNSLG 1889 N+ G Sbjct: 22623 LTVKNASG 22630 Score = 32.3 bits (72), Expect = 4.6 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 1816 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1873 ++LE++EG A F C I E +P V W +DD+++ + + D L++ D Sbjct: 6062 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6117 Query: 1874 GDDDAKYTCKAVNSLGEATCTAELIV 1899 D Y V +G A A L V Sbjct: 6118 LQDMGTY----VVMVGAARAAAHLTV 6139 Score = 32.3 bits (72), Expect = 4.6 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%) Query: 614 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671 P+ AP + L L + G +T + SG P P+V W + ++ E + H Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370 Query: 672 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702 + T +L ++++ + D+G Y NS G Sbjct: 10371 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%) Query: 521 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575 KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+ Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15029 Query: 576 EDHGTYTCLAENALG 590 D G YT A N G Sbjct: 15030 RDSGAYTLTATNPGG 15044 Score = 32.3 bits (72), Expect = 4.6 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%) Query: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584 G + + + G P+P++T +G P++ AE +++++++ D G Y Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20053 Query: 585 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635 A N+ G + V ++ P PT P+ + +++ V Sbjct: 20054 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20100 Query: 636 DGSQVT 641 GSQVT Sbjct: 20101 GGSQVT 20106 Score = 32.3 bits (72), Expect = 4.6 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Query: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679 P + L+ +K G+ V + +SG P P + W + E+Q + E S Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432 Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 + I++ ++G Y + N+ G A + VQ Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20464 Score = 32.3 bits (72), Expect = 4.6 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 +P + + + G + + G P P +W G + R ++ + L I Sbjct: 23246 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23304 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123 D G+YT E N +G T+++ + Sbjct: 23305 TIRDTGEYTLELKNVTGTTSETIKVII 23331 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 1811 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + D Y+C V T TA+LIVE Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%) Query: 1745 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1797 W K G V+ I + S M +I ++ K G+ + + A L + VS + Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399 Query: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1856 + + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 1814 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1870 ++R L +V G R + G P P+V W K D +R+ Q+D D L+I Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12169 Query: 1871 DVCGDDDAKYTCKAVNSLGE 1890 + DD KY+ VN GE Sbjct: 12170 NSTRDDSGKYSLTLVNPAGE 12189 Score = 32.0 bits (71), Expect = 6.0 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786 R++ G S+ I I G P P V W +D L K+ + E N + FT L++ + Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14342 Query: 787 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819 + G++ + ++N G+ S V++ + ++ L Sbjct: 14343 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14375 Score = 32.0 bits (71), Expect = 6.0 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 1816 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 +D+ VV G + I G P P+VVW KD + + E+ +L++ D Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276 Query: 1875 DDDAKYTCKAVN 1886 D +Y K N Sbjct: 18277 TDGGQYILKLSN 18288 Score = 32.0 bits (71), Expect = 6.0 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104 K G+ + + G P P+VTW + R + + +L + D G+Y Sbjct: 22163 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22221 Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164 N +G + +V + V G G VS + E+ WGE Sbjct: 22222 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22273 Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215 T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+ Sbjct: 22274 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22326 Score = 31.6 bits (70), Expect = 7.8 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881 E S R I+G P P V W K + + ++ N +LI+ D D KYT Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13557 Query: 1882 CKAVNSLG--EATCTAELI 1898 N G E T + +++ Sbjct: 13558 ITLKNVAGTKEGTISIKVV 13576 Score = 31.6 bits (70), Expect = 7.8 Identities = 19/80 (23%), Positives = 30/80 (37%) Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V +T ++ G P P+V W +G + +E+ L + D G Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y SN G S T++V Sbjct: 18282 YILKLSNVGGTKSIPITVKV 18301 Score = 31.6 bits (70), Expect = 7.8 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694 G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283 Query: 695 CEAWNSAG 702 + N G Sbjct: 18284 LKLSNVGG 18291 >gi|146219832 myosin light chain kinase 3 [Homo sapiens] Length = 819 Score = 317 bits (811), Expect = 9e-86 Identities = 172/364 (47%), Positives = 232/364 (63%), Gaps = 21/364 (5%) Query: 1411 GTSEPSQES------ELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF 1463 G EP Q+ V P + V DD P ++R V++ E +S Sbjct: 454 GNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVK-ETSISAG 512 Query: 1464 YDI--EERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKL 1521 Y++ E LG G+FGQV R EK T A K K SAK++E+++ EI+IMN L H L Sbjct: 513 YEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNL 572 Query: 1522 VQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGI 1581 +Q DAFE K + +V+E V GGELF+RI DE + LTE + + + RQI EGV Y+H+ I Sbjct: 573 IQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYI 632 Query: 1582 VHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYA 1641 +HLDLKPENI+CVN+TG +IK+IDFGLARR + LKV FGTPEF+APEV+NYE + + Sbjct: 633 LHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFP 692 Query: 1642 TDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLK 1701 TDMWS+GVI Y+L+SGLSPF+G+ D ET+ + + +WDFD + F+ +S++AKDF+S LL Sbjct: 693 TDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLV 752 Query: 1702 KDMKNRLDCTQCLQHPWLMKDTKNMEAK-KLSKDRMK------KYMARRKWQKTGNAVRA 1754 K+ R+ TQCL+H WL N+ AK SK R+K KY+A+RKW+K V A Sbjct: 753 KEKSCRMSATQCLKHEWL----NNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTA 808 Query: 1755 IGRL 1758 RL Sbjct: 809 ANRL 812 >gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens] Length = 154 Score = 313 bits (802), Expect = 1e-84 Identities = 154/154 (100%), Positives = 154/154 (100%) Query: 1761 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1820 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60 Query: 1821 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1880 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY Sbjct: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120 Query: 1881 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Sbjct: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154 Score = 71.6 bits (174), Expect = 7e-12 Identities = 36/92 (39%), Positives = 51/92 (55%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+ Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 I V +D KYTC+A N G T EL VE Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140 Score = 68.6 bits (166), Expect = 6e-11 Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Query: 602 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 E + +L VA KP P F + + DL+V++GS ++ G P PEV+W + Sbjct: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86 Query: 661 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718 I+ES F + SL I +V +D YTC+A NS GE A L V+ +G Sbjct: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145 Score = 62.0 bits (149), Expect = 5e-09 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203 F E +P + P F+ + + V EG RF CKI G P P+V W K + ++ Sbjct: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91 Query: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254 S + +++G L I V DD YTC VN G+A+ +AEL ++ ++ Sbjct: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143 Score = 60.5 bits (145), Expect = 2e-08 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567 V P FS ++D V+EG C + G P P + W + Q I+ +R E G Sbjct: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 L I D +D YTC A N+LG+ +C+A + V Sbjct: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139 Score = 58.5 bits (140), Expect = 6e-08 Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 2/127 (1%) Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440 T P L S++ VS+A + E + P F + EV E +F C++ G Sbjct: 18 TSPLNAEKLESEEDVSQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 75 Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+ Sbjct: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135 Query: 501 TLQVERL 507 L VE + Sbjct: 136 ELIVETM 142 Score = 52.4 bits (124), Expect = 4e-06 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150 E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 CS+ I +D Y C A N G+A C+ ++ V+ E Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146 Score = 45.4 bits (106), Expect = 5e-04 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%) Query: 690 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749 T E S +V + V E +P+F R + G + C I G P Sbjct: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77 Query: 750 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808 P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C Sbjct: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136 Query: 809 LMLQ 812 L+++ Sbjct: 137 LIVE 140 Score = 32.7 bits (73), Expect = 3.5 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%) Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292 K + P + D +V G + K+ G W K + I+ES H +++ E+G Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103 Query: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327 + I++ + CG YT N LG L V Sbjct: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139 >gi|14993776 skeletal myosin light chain kinase [Homo sapiens] Length = 596 Score = 312 bits (800), Expect = 2e-84 Identities = 163/358 (45%), Positives = 227/358 (63%), Gaps = 5/358 (1%) Query: 1415 PSQESELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF-YDIEERLGS 1472 PS++SE+ +D ++ DD P +R V + T S+F + +E LG Sbjct: 234 PSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELRTGNVSSEFSMNSKEALGG 293 Query: 1473 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1532 GKFG V +EK T A K K + K+KE + EI +MN L+H L+Q A E Sbjct: 294 GKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPH 353 Query: 1533 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1592 IV+ +E + GGELFERI+DED+ LTE + + ++RQI +G+ ++HK ++HLDLKPENI+ Sbjct: 354 EIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENIL 413 Query: 1593 CVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652 CVN TG +K+IDFGLARR LKV FGTPEF++PEV+NY+ I TDMWS+GVI Y Sbjct: 414 CVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITY 473 Query: 1653 ILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQ 1712 +L+SGLSPF+GD+D ETL NV S W FD+E F+ +SD+AKDF+SNL+ KD + R++ Q Sbjct: 474 MLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQ 533 Query: 1713 CLQHPW---LMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGL 1767 CL HPW L + K + S+ +KKY+ +R+W+K AV A R ++ L Sbjct: 534 CLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGAL 591 >gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens] Length = 153 Score = 306 bits (785), Expect = 1e-82 Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%) Query: 1761 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1820 MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59 Query: 1821 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1880 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY Sbjct: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119 Query: 1881 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE Sbjct: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153 Score = 71.6 bits (174), Expect = 7e-12 Identities = 36/92 (39%), Positives = 51/92 (55%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+ Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 I V +D KYTC+A N G T EL VE Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139 Score = 67.8 bits (164), Expect = 1e-10 Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%) Query: 611 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 +L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F Sbjct: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94 Query: 670 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718 + SL I +V +D YTC+A NS GE A L V+ +G Sbjct: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144 Score = 63.5 bits (153), Expect = 2e-09 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%) Query: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196 S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K Sbjct: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83 Query: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254 + ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++ Sbjct: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142 Score = 60.5 bits (145), Expect = 2e-08 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567 V P FS ++D V+EG C + G P P + W + Q I+ +R E G Sbjct: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105 Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 L I D +D YTC A N+LG+ +C+A + V Sbjct: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138 Score = 56.6 bits (135), Expect = 2e-07 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%) Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440 T P L S+DV S+A + E + P F + EV E +F C++ G Sbjct: 18 TSPLNAEKLESEDV-SQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 74 Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500 P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+ Sbjct: 75 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134 Query: 501 TLQVERL 507 L VE + Sbjct: 135 ELIVETM 141 Score = 52.4 bits (124), Expect = 4e-06 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150 E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 CS+ I +D Y C A N G+A C+ ++ V+ E Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145 Score = 44.3 bits (103), Expect = 0.001 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%) Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772 ++PH +P+F R + G + C I G P P V W +D +++ +++ HF++ Sbjct: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98 Query: 773 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 +ED +L++ V +Y N +GE +C L+++ Sbjct: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139 Score = 32.7 bits (73), Expect = 3.5 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%) Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292 K + P + D +V G + K+ G W K + I+ES H +++ E+G Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102 Query: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327 + I++ + CG YT N LG L V Sbjct: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138 >gi|167466233 myosin light chain kinase family, member 4 [Homo sapiens] Length = 388 Score = 297 bits (760), Expect = 8e-80 Identities = 145/274 (52%), Positives = 195/274 (71%), Gaps = 3/274 (1%) Query: 1448 DYRTVTINTEQKVSDFYDIE--ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN 1505 D+R VT + V+ FY + E LG G+FGQV + E T A K K K+KE Sbjct: 89 DHRIVTAK-QGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEE 147 Query: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565 ++ EIS+MN L H L+Q DAFE K +IV+V+E V GGELF+RIIDE + LTE + I + Sbjct: 148 VKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILF 207 Query: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 1625 M+QI EG+ ++H+ I+HLDLKPENI+CVN+ +IK+IDFGLARR + LKV FGTP Sbjct: 208 MKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTP 267 Query: 1626 EFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAF 1685 EF+APEV+NY+ + + TDMWS+GVI Y+L+SGLSPF+GDND ETL N+ + WD +DE F Sbjct: 268 EFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEF 327 Query: 1686 DEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWL 1719 +IS++AK+FIS LL K+ R+ ++ L+HPWL Sbjct: 328 QDISEEAKEFISKLLIKEKSWRISASEALKHPWL 361 >gi|89363047 death-associated protein kinase 1 [Homo sapiens] Length = 1430 Score = 277 bits (709), Expect = 6e-74 Identities = 150/364 (41%), Positives = 223/364 (61%), Gaps = 21/364 (5%) Query: 1452 VTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE------KEN 1505 +T+ ++ V D+YD E LGSG+F V + EK T +A KF K K +E+ Sbjct: 1 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED 60 Query: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565 I +E+SI+ + HP ++ + +E K +++++LE+V+GGELF+ + +++ LTE E ++ Sbjct: 61 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE-SLTEEEATEF 119 Query: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFG 1623 ++QI GV Y+H I H DLKPENIM +++ RIK+IDFGLA +++ K +FG Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFG 179 Query: 1624 TPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDE 1683 TPEFVAPE++NYEP+G DMWSIGVI YIL+SG SPF+GD ETLANV++ ++F+DE Sbjct: 180 TPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDE 239 Query: 1684 AFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLM-KDTKNMEAKKLS---KDRMKKY 1739 F S AKDFI LL KD K R+ LQHPW+ KDT+ ++K S ++ KK+ Sbjct: 240 YFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKF 299 Query: 1740 MARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1799 AR+KW+++ + RLS S LS S L+ E + V +A + A Sbjct: 300 AARKKWKQSVRLISLCQRLSR----SFLSRSNMSVARSDDTLD----EEDSFVMKAIIHA 351 Query: 1800 VAEE 1803 + ++ Sbjct: 352 INDD 355 >gi|14670383 death-associated kinase 2 [Homo sapiens] Length = 370 Score = 268 bits (685), Expect = 4e-71 Identities = 144/350 (41%), Positives = 215/350 (61%), Gaps = 20/350 (5%) Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK------EKENIRQEI 1510 +QKV DFYDI E LGSG+F V + EK T +A KF K ++ +E I +E+ Sbjct: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75 Query: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570 SI+ + H ++ D +E + ++V++LE+VSGGELF+ + ++ L+E E +++QI Sbjct: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQIL 134 Query: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKTGT--RIKLIDFGLARRLENAGSLKVLFGTPEFV 1628 +GV Y+H + I H DLKPENIM ++K IKLIDFGLA +E+ K +FGTPEFV Sbjct: 135 DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194 Query: 1629 APEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEI 1688 APE++NYEP+G DMWSIGVI YIL+SG SPF+GD ETLAN+T+ ++DFD+E F + Sbjct: 195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQT 254 Query: 1689 SDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMK-DTKNMEAKK---LSKDRMKKYMARRK 1744 S+ AKDFI LL K+ + RL + L+HPW+ D + ++ ++ + +K RR+ Sbjct: 255 SELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRR 314 Query: 1745 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQ 1794 W+ + + V L+ M K P L + ++EED+++ Sbjct: 315 WKLSFSIVSLCNHLTRSLM-------KKVHLRPDEDLRNCESDTEEDIAR 357 >gi|4557511 death-associated protein kinase 3 [Homo sapiens] Length = 454 Score = 259 bits (662), Expect = 2e-68 Identities = 131/301 (43%), Positives = 191/301 (63%), Gaps = 19/301 (6%) Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFK------AYSAKEKENIRQEI 1510 ++ V D Y++ E LGSG+F V + +K T K +A KF K + +E I +E+ Sbjct: 6 QEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREV 65 Query: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570 +I+ + HP ++ D FE K ++V++LE+VSGGELF+ + +++ LTE E ++++QI Sbjct: 66 NILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKE-SLTEDEATQFLKQIL 124 Query: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFGTPEFV 1628 +GV Y+H + I H DLKPENIM ++K RIKLIDFG+A ++E K +FGTPEFV Sbjct: 125 DGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFV 184 Query: 1629 APEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEI 1688 APE++NYEP+G DMWSIGVI YIL+SG SPF+G+ ETL N+++ +DFD+E F Sbjct: 185 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNT 244 Query: 1689 SDDAKDFISNLLKKDMKNRLDCTQCLQHPWLM----------KDTKNMEAKKLSKDRMKK 1738 S+ AKDFI LL KD K R+ Q L+H W+ + E ++L R+K+ Sbjct: 245 SELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKE 304 Query: 1739 Y 1739 Y Sbjct: 305 Y 305 >gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] Length = 2986 Score = 246 bits (629), Expect = 1e-64 Identities = 175/588 (29%), Positives = 277/588 (47%), Gaps = 47/588 (7%) Query: 1194 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1245 ENT E R+PK L + + + ++ P +M P IQ PE Sbjct: 2415 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 2474 Query: 1246 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1296 D G++V L KV G T TW + I ++++ V + ++G L Sbjct: 2475 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 2534 Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356 I + G YT + N G+ + V P P P A + +S+ L W S Sbjct: 2535 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 2593 Query: 1357 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 G + Y++E + ++ W++ +A+ T ++DL P Y+FRV A N +G S P Sbjct: 2594 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 2653 Query: 1416 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1473 S+ SE + PE D TI+ ++ Y +G G Sbjct: 2654 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 2693 Query: 1474 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1533 +F V + + K TRK A KF K+KE E +++ L HP+ + D +E + Sbjct: 2694 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 2752 Query: 1534 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1593 +++LE++ G L + +++ D EL E + Y+R I E ++Y+H + HLD+KPEN++ Sbjct: 2753 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 2811 Query: 1594 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652 + R+KLID A ++ + L G PEF APEVI P+ TD+WSIGV+ Y Sbjct: 2812 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 2871 Query: 1653 ILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQ 1712 +++SG+SPF+ ++ ET NV + F E F +S+ A+DFI+ +L++D + R Sbjct: 2872 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 2931 Query: 1713 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1760 CLQHPWL + L R+ ++ RRK Q N VR I + S Sbjct: 2932 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 2976 Score = 71.2 bits (173), Expect = 9e-12 Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 560 + EVAP F L D + G +LQC V G P P ITW Q I Y S+ Sbjct: 2466 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 2525 Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620 C++G L I + +P+D G YTC+A N G S SA V V +P AP++P Sbjct: 2526 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 2575 Query: 621 TA 622 A Sbjct: 2576 IA 2577 Score = 60.1 bits (144), Expect = 2e-08 Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%) Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208 P+ E P+F L V G CK+ GRP+P +TW + + SA + Sbjct: 2463 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 2522 Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266 VS +G L+I + D G+YTC+ N G S SA + +QG+ +A NR +E Sbjct: 2523 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 2582 Query: 267 TNSDVR 272 T+ +R Sbjct: 2583 TSVILR 2588 Score = 58.9 bits (141), Expect = 5e-08 Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%) Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 1056 S E + AV QP+ P P L P+ A AE+ G+ K Sbjct: 2343 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 2400 Query: 1057 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1093 L+ + E++ KN D+ + T++ + SE Sbjct: 2401 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 2460 Query: 1094 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1142 Q AP F L DV G ++LQC+V P TI W + + T Sbjct: 2461 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 2520 Query: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202 + + S + ++ I +P+D G+Y C+A ND G S V V PA+ N + + Sbjct: 2521 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 2580 Query: 1203 S 1203 S Sbjct: 2581 S 2581 Score = 50.1 bits (118), Expect = 2e-05 Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%) Query: 598 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647 V+V E SS +SE +L + AP FL L D+ + G V + +V Sbjct: 2436 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 2495 Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 702 G P P + W I ++++ + + +L I + P+D+G YTC A N G Sbjct: 2496 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 2555 Query: 703 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 757 T A + VQ P +P I++ RS T+ L S +C I+G TV + + Sbjct: 2556 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 2610 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 G + + + V D + LV++ + P Q+ + N G Sbjct: 2611 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 2649 Score = 45.8 bits (107), Expect = 4e-04 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87 AP F++P ++ G T + +V G P+P +TW Q I S + + G Sbjct: 2470 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 2529 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125 +L I + +D G YTC ATN G + + V+G Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 2567 Score = 45.4 bits (106), Expect = 5e-04 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1862 V P F + D+ + G CK+ G P P + W DQ+I ++ + Y + Sbjct: 2469 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 2528 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 G +L I ++ D YTC A N G + +A + V+ Sbjct: 2529 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 2566 Score = 44.7 bits (104), Expect = 9e-04 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 4/80 (5%) Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYE----DAGSHYLCLLKARTRDSGTY 485 TV +C+V G PKP + W + + S Y D+G L + +DSG Y Sbjct: 2487 TVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIY 2546 Query: 486 SCTASNAQGQLSCSWTLQVE 505 +C A+N G S S T++V+ Sbjct: 2547 TCIATNDHGTTSTSATVKVQ 2566 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 775 P F+ VT LG +V++ C + G P PT+ W + + DT + + Sbjct: 2471 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 2529 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 TL + + P +G Y + N G S ++ +Q A Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 2570 >gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] Length = 1289 Score = 246 bits (629), Expect = 1e-64 Identities = 175/588 (29%), Positives = 277/588 (47%), Gaps = 47/588 (7%) Query: 1194 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1245 ENT E R+PK L + + + ++ P +M P IQ PE Sbjct: 718 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 777 Query: 1246 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1296 D G++V L KV G T TW + I ++++ V + ++G L Sbjct: 778 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 837 Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356 I + G YT + N G+ + V P P P A + +S+ L W S Sbjct: 838 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 896 Query: 1357 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415 G + Y++E + ++ W++ +A+ T ++DL P Y+FRV A N +G S P Sbjct: 897 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 956 Query: 1416 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1473 S+ SE + PE D TI+ ++ Y +G G Sbjct: 957 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 996 Query: 1474 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1533 +F V + + K TRK A KF K+KE E +++ L HP+ + D +E + Sbjct: 997 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 1055 Query: 1534 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1593 +++LE++ G L + +++ D EL E + Y+R I E ++Y+H + HLD+KPEN++ Sbjct: 1056 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 1114 Query: 1594 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652 + R+KLID A ++ + L G PEF APEVI P+ TD+WSIGV+ Y Sbjct: 1115 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 1174 Query: 1653 ILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQ 1712 +++SG+SPF+ ++ ET NV + F E F +S+ A+DFI+ +L++D + R Sbjct: 1175 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 1234 Query: 1713 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1760 CLQHPWL + L R+ ++ RRK Q N VR I + S Sbjct: 1235 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 1279 Score = 71.2 bits (173), Expect = 9e-12 Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%) Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 560 + EVAP F L D + G +LQC V G P P ITW Q I Y S+ Sbjct: 769 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 828 Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620 C++G L I + +P+D G YTC+A N G S SA V V +P AP++P Sbjct: 829 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 878 Query: 621 TA 622 A Sbjct: 879 IA 880 Score = 60.1 bits (144), Expect = 2e-08 Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%) Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208 P+ E P+F L V G CK+ GRP+P +TW + + SA + Sbjct: 766 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 825 Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266 VS +G L+I + D G+YTC+ N G S SA + +QG+ +A NR +E Sbjct: 826 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 885 Query: 267 TNSDVR 272 T+ +R Sbjct: 886 TSVILR 891 Score = 58.9 bits (141), Expect = 5e-08 Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%) Query: 998 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 1056 S E + AV QP+ P P L P+ A AE+ G+ K Sbjct: 646 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 703 Query: 1057 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1093 L+ + E++ KN D+ + T++ + SE Sbjct: 704 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 763 Query: 1094 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1142 Q AP F L DV G ++LQC+V P TI W + + T Sbjct: 764 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 823 Query: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202 + + S + ++ I +P+D G+Y C+A ND G S V V PA+ N + + Sbjct: 824 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 883 Query: 1203 S 1203 S Sbjct: 884 S 884 Score = 50.1 bits (118), Expect = 2e-05 Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%) Query: 598 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647 V+V E SS +SE +L + AP FL L D+ + G V + +V Sbjct: 739 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 798 Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 702 G P P + W I ++++ + + +L I + P+D+G YTC A N G Sbjct: 799 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 858 Query: 703 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 757 T A + VQ P +P I++ RS T+ L S +C I+G TV + + Sbjct: 859 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 913 Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801 G + + + V D + LV++ + P Q+ + N G Sbjct: 914 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 952 Score = 45.8 bits (107), Expect = 4e-04 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87 AP F++P ++ G T + +V G P+P +TW Q I S + + G Sbjct: 773 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 832 Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125 +L I + +D G YTC ATN G + + V+G Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 870 Score = 45.4 bits (106), Expect = 5e-04 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1862 V P F + D+ + G CK+ G P P + W DQ+I ++ + Y + Sbjct: 772 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 831 Query: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 G +L I ++ D YTC A N G + +A + V+ Sbjct: 832 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 869 Score = 44.7 bits (104), Expect = 9e-04 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 4/80 (5%) Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYE----DAGSHYLCLLKARTRDSGTY 485 TV +C+V G PKP + W + + S Y D+G L + +DSG Y Sbjct: 790 TVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIY 849 Query: 486 SCTASNAQGQLSCSWTLQVE 505 +C A+N G S S T++V+ Sbjct: 850 TCIATNDHGTTSTSATVKVQ 869 Score = 35.0 bits (79), Expect = 0.70 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 775 P F+ VT LG +V++ C + G P PT+ W + + DT + + Sbjct: 774 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 832 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816 TL + + P +G Y + N G S ++ +Q A Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 873 >gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo sapiens] Length = 370 Score = 224 bits (570), Expect = 8e-58 Identities = 113/316 (35%), Positives = 190/316 (60%), Gaps = 4/316 (1%) Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKE-NIRQEISIMNCL 1516 + + D YD + LG+G F +V +K+T+K+ A K + + KE ++ EI++++ + Sbjct: 14 EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKI 73 Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576 HP +V D +E ++ +++++VSGGELF+RI+++ F TER+ + + Q+ + V+Y+ Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGF-YTERDASRLIFQVLDAVKYL 132 Query: 1577 HKQGIVHLDLKPENIMCVN-KTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635 H GIVH DLKPEN++ + ++I + DFGL++ + L GTP +VAPEV+ Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQ 192 Query: 1636 EPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDF 1695 +P A D WSIGVI YIL+ G PF +ND + + A ++FD +D+ISD AKDF Sbjct: 193 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252 Query: 1696 ISNLLKKDMKNRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1754 I +L++KD + R C Q LQHPW+ DT + + +++KK A+ KW++ NA Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAV 312 Query: 1755 IGRLSSMAMISGLSGR 1770 + + + + + G+ Sbjct: 313 VRHMRKLQLGTSQEGQ 328 >gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1 [Homo sapiens] Length = 357 Score = 223 bits (568), Expect = 1e-57 Identities = 116/325 (35%), Positives = 188/325 (57%), Gaps = 4/325 (1%) Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516 + + ++ +E LG+G F +V EK T K++A K + K KE+ I EI+++ + Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76 Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576 H +V D +E ++ +V+++VSGGELF+RI+++ F TE++ +RQ+ + V Y+ Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135 Query: 1577 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635 H+ GIVH DLKPEN++ ++ ++I + DFGL++ + GTP +VAPEV+ Sbjct: 136 HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195 Query: 1636 EPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDF 1695 +P A D WSIGVI YIL+ G PF +ND++ + A ++FD +D+ISD AKDF Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255 Query: 1696 ISNLLKKDMKNRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1754 I NL++KD R C Q +HPW+ DT N + +++K A+ KW++ NA Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315 Query: 1755 IGRLSSMAMISGLSGRKSSTGSPTS 1779 + + + + S L +S S S Sbjct: 316 VRHMRKLHLGSSLDSSNASVSSSLS 340 >gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2 [Homo sapiens] Length = 385 Score = 223 bits (568), Expect = 1e-57 Identities = 116/325 (35%), Positives = 188/325 (57%), Gaps = 4/325 (1%) Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516 + + ++ +E LG+G F +V EK T K++A K + K KE+ I EI+++ + Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76 Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576 H +V D +E ++ +V+++VSGGELF+RI+++ F TE++ +RQ+ + V Y+ Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135 Query: 1577 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635 H+ GIVH DLKPEN++ ++ ++I + DFGL++ + GTP +VAPEV+ Sbjct: 136 HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195 Query: 1636 EPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDF 1695 +P A D WSIGVI YIL+ G PF +ND++ + A ++FD +D+ISD AKDF Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255 Query: 1696 ISNLLKKDMKNRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1754 I NL++KD R C Q +HPW+ DT N + +++K A+ KW++ NA Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315 Query: 1755 IGRLSSMAMISGLSGRKSSTGSPTS 1779 + + + + S L +S S S Sbjct: 316 VRHMRKLHLGSSLDSSNASVSSSLS 340 >gi|109255245 serine/threonine kinase 17a [Homo sapiens] Length = 414 Score = 207 bits (526), Expect = 1e-52 Identities = 100/269 (37%), Positives = 174/269 (64%), Gaps = 5/269 (1%) Query: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMNCLH-HPKLVQCVD 1526 LG GKF V + ++K + K +A KF + + + I EI+++ +P ++ + Sbjct: 67 LGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHE 126 Query: 1527 AFEEKANIVMVLEIVSGGELFERII-DEDFELTERECIKYMRQISEGVEYIHKQGIVHLD 1585 +E + +++VLE +GGE+F++ + D + E++ + MRQI EGV ++H + +VHLD Sbjct: 127 VYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLD 186 Query: 1586 LKPENIMCVNKTGTR-IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDM 1644 LKP+NI+ +++ IK++DFGL+R L+N+ L+ + GTPE+VAPE+++Y+PI ATDM Sbjct: 187 LKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDM 246 Query: 1645 WSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDM 1704 WSIGV+ Y++++G+SPF+G++ ET N++ + +E FD +S+ A DFI LL K Sbjct: 247 WSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKP 306 Query: 1705 KNRLDCTQCLQHPWLMKDTKNMEAKKLSK 1733 ++R +CL+HPWL + + + ++ K Sbjct: 307 EDRATAEECLKHPWLTQSSIQEPSFRMEK 335 >gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF isoform b [Homo sapiens] Length = 7968 Score = 202 bits (514), Expect = 3e-51 Identities = 103/298 (34%), Positives = 172/298 (57%), Gaps = 2/298 (0%) Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1517 +K+ FY+++E +G G FG V R+ K + + A KF S + R+ I+ L Sbjct: 6462 RKLHSFYEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRER-DILAALS 6520 Query: 1518 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1577 HP + +D FE + ++++LE+ S EL +R+ + +TE E Y++Q+ EG+ Y+H Sbjct: 6521 HPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGV-VTEAEVKVYIQQLVEGLHYLH 6579 Query: 1578 KQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEP 1637 G++HLD+KP NI+ V+ IK+ DFG A+ + A +G+PEFV+PE+I P Sbjct: 6580 SHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNP 6639 Query: 1638 IGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFIS 1697 + A+D+W++GVI Y+ ++ SPF G++D TL NV + +S+DAKDFI Sbjct: 6640 VSEASDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIK 6699 Query: 1698 NLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAI 1755 L++ + R QCL HPW +K EA ++ ++K +AR +WQ++ + ++I Sbjct: 6700 ATLQRAPQARPSAAQCLSHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSI 6757 Score = 143 bits (361), Expect = 1e-33 Identities = 156/641 (24%), Positives = 245/641 (38%), Gaps = 96/641 (14%) Query: 129 KQLGQPVVSKTLGDRFSA-PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGR 187 K LG P + K +A + R + + P F+ G + G R C + + Sbjct: 4865 KDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASK 4924 Query: 188 PQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246 + WLK V L + + +G L I G+++ D G YTC V N G+ + SA Sbjct: 4925 ADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984 Query: 247 ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP 306 + + G +S S + D + + + + S + + S G + Sbjct: 4985 CVVVSGSESEAES---SSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAE 5041 Query: 307 P-----WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361 P W + + + E+ ++ + + + T I ++ V+ PR + Sbjct: 5042 PEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLG-IGVEIKLVEQGPRRVEM 5100 Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421 + ++ PAP P P P L + D A P F ++ Q Sbjct: 5101 CI------SKETPAPVVP---PEPLPSLLTSD------------------AAPVFLTELQ 5133 Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481 +QEV++ V F C V+G P P V WF +G + + + + G H L + D Sbjct: 5134 NQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPAD 5193 Query: 482 SGTYSCTASNAQGQLSCSWTLQVERLAV--------MEVAPSFSSV-------------- 519 G Y C A N+ G S L+V+ + E + FS+ Sbjct: 5194 MGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTEST 5253 Query: 520 ------------LKDCAVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQ---YARSTCEA 563 L+D V G Q V+G P PR+ W +GQP+ + R T + Sbjct: 5254 TDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKK 5313 Query: 564 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAP 617 + L I ED G Y NA+G SA + V EK +S E L+P Sbjct: 5314 ILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVP--- 5370 Query: 618 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI------QESEDFHF 671 P L+ + KV GS +T +V+V G P P V WL E ++ + Sbjct: 5371 -----PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425 Query: 672 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 QHSL + +V + GTYTC A N+AG+ A L V Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466 Score = 129 bits (323), Expect = 4e-29 Identities = 136/528 (25%), Positives = 221/528 (41%), Gaps = 55/528 (10%) Query: 1215 GTESDATVKKKPAPKTPPKAAMP-----PQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269 G E + +KKP + + + P ++ D+ V G+SV L +V+ Sbjct: 7435 GLEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQA 7494 Query: 1270 TWMKFRKQIQESEHMKVENS-ENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT-V 1327 TW K ++ S + + + +N LTIL E G YT V N LG+ V T V Sbjct: 7495 TWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGT----VTTTGV 7550 Query: 1328 VDKPDPPAGTPCAS--DIRSSSLTLSWYG-SSYDGGSAVQSYSIEIWDSANKTWKELAT- 1383 + K + P+ +PC ++ + + L W SY + + S+E +W LA+ Sbjct: 7551 LRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLE-----GGSWTTLASD 7605 Query: 1384 ----CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439 C TS L Y FR ++ G S SE +G P E E S Sbjct: 7606 IFDCCYLTS----KLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG-PSHLASEEE-SQ 7659 Query: 1440 DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYS 1499 +P +T T+ + G+F V + EK + + A K Y Sbjct: 7660 GRSAQPLPSTKTFAFQTQ------------IQRGRFSVVRQCWEKASGRALAAKIIP-YH 7706 Query: 1500 AKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTE 1559 K+K + +E + L HP L Q A+ ++V++LE+ SG EL + E +E Sbjct: 7707 PKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLP-CLAERASYSE 7765 Query: 1560 RECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLK 1619 E Y+ Q+ +Y+H Q I+HLDL+ EN++ +K++D G A+ L K Sbjct: 7766 SEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEY--NLLKVVDLGNAQSLSQE---K 7820 Query: 1620 VLFGTP-----EFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVT 1674 VL E +APE++ + TD+W+IGV +I++S P + + + Sbjct: 7821 VLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLR 7880 Query: 1675 SATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKD 1722 + +S A F+ + L R + CLQ PWL ++ Sbjct: 7881 KGLVRL-SRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEE 7927 Score = 119 bits (298), Expect = 3e-26 Identities = 106/376 (28%), Positives = 142/376 (37%), Gaps = 61/376 (16%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS-IEVYEDAGSHYL 472 P F +P S V+E FRC V G P+P V+W +G + +G + V E + L Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV----------------------- 509 + AR RD GTY A N G S + L V+ A Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229 Query: 510 --MEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 565 E AP+ S+ + C V EG+ L C V G P P W +GQ + R Sbjct: 230 MRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289 Query: 566 AE----LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621 A+ L I D G YTC A N +GQ S V V E P Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE-----------------PA 332 Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 P F + L DL+V + T +V P E W + S + E+ GT+ L Sbjct: 333 VP-FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLT 390 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 ++ V +D Y CE + RT A L VQ PR +G + + Sbjct: 391 VRNVSADDDAVYICETPEGS---RTVAELAVQ------GNLLRKLPRKTAVRVGDTAMF- 440 Query: 742 CAIAGDPFPTVHWLRD 757 C P VHWLR+ Sbjct: 441 CVELAVPVGPVHWLRN 456 Score = 119 bits (297), Expect = 4e-26 Identities = 93/337 (27%), Positives = 143/337 (42%), Gaps = 32/337 (9%) Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464 M+ + S P+F ++P++ V + C++ G P P+V+W + PV + Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPV-AAGARFRLA 59 Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE-RLAVMEVAPSFSSVLKDC 523 +D + L +L DSG Y C A NA G+ + LQV+ A E AP F Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSI 119 Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLN----GQPIQYARSTCEAGVAE-LHIQDALPEDH 578 V EG + +C V G+P P ++W + G+P E G A L I+ A P D Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDG 179 Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKSS------------------RKSEYLLPVAPSKP 620 GTY AEN LG S +A + V + R+ AP+ P Sbjct: 180 GTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239 Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680 + G V +G ++ V+G P PE +W +G + E H Q + Sbjct: 240 PS----TGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENF 294 Query: 681 CIQEVF--PEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 ++ +F D G YTC A N G+ + ++ V+EP Sbjct: 295 VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREP 331 Score = 117 bits (292), Expect = 1e-25 Identities = 287/1336 (21%), Positives = 478/1336 (35%), Gaps = 229/1336 (17%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 P KF L EG C+++ V W KG L+ R + ++ L+ Sbjct: 3449 PAKFTEGLRNEEAVEGATAMLWCELS--KVAPVEWRKGPENLRDGDRYILRQEGTRCELQ 3506 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 I G+ D G Y C+ G+ SA L+I+ L + F+ + K N + R+ T V+ Sbjct: 3507 ICGLAMADAGEYLCVC----GQERTSATLTIRALPAR---FIEDVK--NQEAREGATAVL 3557 Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVL- 338 E L+S A + + S R G + + + + D T + V Sbjct: 3558 QCE--LNSA-APVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMAD---TGEYSCVCG 3611 Query: 339 -QKTSSSITLQAARVQ------PEPRAPG--------LGVLSP----SGEERKRPAPPRP 379 ++TS+ +T++A ++ E G L ++P G E R Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPVEWWKGHETLRDGDRHS 3671 Query: 380 ATFPTRQPGLGSQDVVSKAANRRIPMEG-QRDSAFPKFESKP-------QSQEVKENQTV 431 + L + +V++ A + M G +R SA + P +++E E T Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTA 3731 Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL------CLLKAR---TRDS 482 CE+S + PV ++G E D H L C L+ R D+ Sbjct: 3732 TLWCELS-----------KAAPVEWRKGH-ETLRDGDRHSLRQDGSRCELQIRGLAVVDA 3779 Query: 483 GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542 G YSC GQ S TL V L F +K+ EG VLQC + + Sbjct: 3780 GEYSCVC----GQERTSATLTVRALPAR-----FIEDVKNQEAREGATAVLQCEL--SKA 3828 Query: 543 PRITWLLNGQPIQYAR--STCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599 + W + ++ S + G EL I D G Y+C+ GQ SA +T Sbjct: 3829 APVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLT 3884 Query: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 V AP P+F + L L+ +GS T+ ++S P V+W Sbjct: 3885 VR--------------APQ----PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKG 3925 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719 G ++Q + +G L +Q++ EDTG YTC + G T A LTV Sbjct: 3926 GLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGSQATSATLTV----TAA 3977 Query: 720 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779 F+ + + G + + C ++ +V W R G ++++Q+ L Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCELS-RAGASVEW-RKGSLQLFPCAKYQMVQDGAAAEL 4035 Query: 780 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839 +++ V+ AG Y + S V + R +E LC A+ Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAE 4095 Query: 840 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR-----------QHTEEAIR 888 G ++ L+ G E R +L ++E + Q T ++R Sbjct: 4096 SGAVVQW--LKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLR 4153 Query: 889 QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSP 948 E E R L+ +V+ E ++F + R T + + Sbjct: 4154 VTEPEVTIVRGLVDAEVTAD------------EDVEFSCEVSR--AGATGVQWCLQGLPL 4199 Query: 949 QQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAV 1008 Q + V + G T + V P T F LG + SS+ T+ A V Sbjct: 4200 QSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH--LG-------NHASSAQLTVRAPEV 4250 Query: 1009 ESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDEN-LKSASKEE- 1066 +PL + Q + + A + A E +G N + + E+ Sbjct: 4251 TILEPLQDVQ-------LSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQG 4303 Query: 1067 ------LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120 L K D H GT +E + + + L++V EG + L +CQ Sbjct: 4304 TLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVR-GLENVEALEGGEALFECQ 4362 Query: 1121 VSSDPPATIIWTLNGKTLKTTK--FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178 +S A W L+ + + T++ ++ + G + ++ P+D Sbjct: 4363 LSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQD-------------- 4408 Query: 1179 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238 SC+VT L + T + TV+ Sbjct: 4409 ---SCRVTF----------------------LAGDMVTSAFLTVR-----------GWRL 4432 Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ-ESEHMKVENSENGSKLT 1296 +I++ ++ VRAG ++ P+ +W +Q + V + L Sbjct: 4433 EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALL 4492 Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356 + +A+ H G T + + A LTV+ PDPP + S ++TLSW Sbjct: 4493 LRSAQPHHAGEVTFACRDAV----ASARLTVLGLPDPPEDAEVVAR-SSHTVTLSWAAPM 4547 Query: 1357 YDGGSAVQSYSIEIWDSANKTWK---ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 DGG + Y +E+ + A W+ EL V L P Y+FRV A+ G Sbjct: 4548 SDGGGGLCGYRVEVKEGATGQWRLCHELVP--GPECVVDGLAPGETYRFRVAAVGPVGAG 4605 Query: 1414 EPSQESELTTVGEKPE 1429 EP + + E P+ Sbjct: 4606 EPVHLPQTVRLAEPPK 4621 Score = 117 bits (292), Expect = 1e-25 Identities = 117/500 (23%), Positives = 199/500 (39%), Gaps = 81/500 (16%) Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85 ++P+ P F + + G T K RV G P+P ++W+++G+ + +L Sbjct: 6007 ALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDP 6066 Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145 G+ +L++ ++ D G+Y C A + +G TLG Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGN----------------------CSTLG---- 6100 Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205 I + PP+F K+ EG+ +F+C I G P PQ+ W K L Sbjct: 6101 --------KILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGN 6152 Query: 206 RV-SVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG--LDSANRSFV 261 + ++SE ++G+ VL I +++D+G+Y C +VN G A SAEL IQ L + + Sbjct: 6153 KFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212 Query: 262 RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321 + A D E + E + K P+ G P Sbjct: 6213 EQLVAAVEDTTLERAD----------QEVTSVLKRLLGPKAPG------------PSTGD 6250 Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQP--EPRAPGLGVLSPSGEERKRPAPPRP 379 L PR A P LQ+T S + P PR P + +E + A + Sbjct: 6251 LTGPGPCPRGA---PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAIARAQE 6307 Query: 380 ATFPTRQ-----PGLGSQDVVSKAANRRIPMEGQRDSAFPKFE---SKPQSQEV------ 425 T P R PG G+ +++ + + QR + + ++P S +V Sbjct: 6308 WTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQ 6367 Query: 426 -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 + T +F + G P+P V W+ + + + ++ ++ L L ++D+G Sbjct: 6368 AQTGGTAQFEAIIEGDPQPSVTWYKDSVQL-VDSTRLSQQQEGTTYSLVLRHVASKDAGV 6426 Query: 485 YSCTASNAQGQLSCSWTLQV 504 Y+C A N GQ+ C L V Sbjct: 6427 YTCLAQNTGGQVLCKAELLV 6446 Score = 117 bits (292), Expect = 1e-25 Identities = 118/442 (26%), Positives = 176/442 (39%), Gaps = 53/442 (11%) Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 P FE + + +TVK C V+G PKP ++W+ +G V+ I + + GS L Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073 Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 L DSG Y C A++A G +CS ++ +++V P F + ++ +EG+D Sbjct: 6074 LDSLTGVDSGQYMCFAASAAG--NCSTLGKI----LVQVPPRFVNKVRASPFVEGEDAQF 6127 Query: 534 QCSVRGTPVPRITWLLNGQPIQYAR-----STCEAGVAELHIQDALPEDHGTYTCLAENA 588 C++ G P P+I W +G + S +G+ L I+ A ED G Y C N Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187 Query: 589 LGQVSCSAWVTVH----------------------------EKKSSRKSEYLLPVAPSKP 620 LG SA + + ++ +S L P AP Sbjct: 6188 LGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPS 6247 Query: 621 TAPIFLQGL----SDLKVMDGSQ--VTMTVQVSGNPP--PEVIWLHNGNEIQESEDFHFE 672 T + G + GSQ VT T + PP P+ + LH G E QE E Sbjct: 6248 TGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRVPQPL-LHEGPE-QEPEAIARA 6305 Query: 673 QRGTQHSLCIQEVFP-EDTGTYTCEAWNSAGEVRTQAVLTVQ--EPHDGTQPWFISKPRS 729 Q T +P TG + + TQ T Q + H P Sbjct: 6306 QEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIED 6365 Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 V A G + I GDP P+V W +D L D+ Q ++LVL+ V A Sbjct: 6366 VQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLV-DSTRLSQQQEGTTYSLVLRHVASKDA 6424 Query: 790 GQYEILLKNRVGECSCQVSLML 811 G Y L +N G+ C+ L++ Sbjct: 6425 GVYTCLAQNTGGQVLCKAELLV 6446 Score = 112 bits (279), Expect = 5e-24 Identities = 106/409 (25%), Positives = 170/409 (41%), Gaps = 51/409 (12%) Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 +V+E + FRC +S V WFL+ TP+ E + + G H L L + +DSG Sbjct: 3015 DVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG 3074 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 T A + + + L V E FS L D + EG+D L C +P Sbjct: 3075 TIYFEAGDQRASAA---------LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP 3125 Query: 544 RITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W +G+ ++ + + E A+L I A +D G Y C A G S+ V V Sbjct: 3126 -VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 3180 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 H + PV F + L DL+V++G T+ +S P V W + Sbjct: 3181 HAR----------PVR--------FQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 N ++ + + Q G L ++ + P+D+G Y+C S G+ T A LTV Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTV----TALP 3273 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 FI K R+ A+ G + + C ++ V W R G +D + + Q+ + L Sbjct: 3274 AQFIGKLRNKEATEGATATLRCELS--KAAPVEW-RKGSETLRDGDRYCLRQDGAMCELQ 3330 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCE 829 ++ + A +Y + GE SL ++ A + R R S E Sbjct: 3331 IRGLAMVDAAEYSCV----CGEERTSASLTIRPMPAHFIGRLRHQESIE 3375 Score = 112 bits (279), Expect = 5e-24 Identities = 90/346 (26%), Positives = 141/346 (40%), Gaps = 43/346 (12%) Query: 507 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCE 562 L + AP F + L++ V +G C V G P+P + W +G+ ++ Y + + Sbjct: 5119 LLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178 Query: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH-------------EKKSSRKS 609 G +L I +P D G Y CLAEN++G S A + V E S + Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238 Query: 610 EYLLPVAPSKPTA--------PIFLQGLSDLKVMDGSQVT-MTVQVSGNPPPEVIWLHNG 660 + L + T P ++ L DL+V G+++ ++V G P P + W +G Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 + S + H+L I V ED+G Y N+ G + A L V+ P + + Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE 5358 Query: 721 ------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA-----LCK 763 P + + G S+ S + G P PTVHWLR+ + Sbjct: 5359 KPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418 Query: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 DT + V + +LVL V H G Y + N G+ C SL Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464 Score = 104 bits (259), Expect = 9e-22 Identities = 133/567 (23%), Positives = 214/567 (37%), Gaps = 80/567 (14%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P+F T+ VV G+ SC+I G P PQV+W K P+ AR +++ + L I Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280 + D G Y C N G+A + L + + ++ + + Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA---------------EAACAEQAPHFLL 114 Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340 + + + E + + C + GGSP A + R + D PR + Sbjct: 115 RPTSIRVREGSEATFRC---RVGGSPRPAVSWSKDGRRLGE----PDGPRVRVEE---LG 164 Query: 341 TSSSITLQAARVQPEPRAPG---LGVLSPSGEERKRPA--PPRPATFPTRQPGLGSQDVV 395 +S++ ++AAR PR G + +P G A A +PG + ++ Sbjct: 165 EASALRIRAAR----PRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALL 220 Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455 + RR M + A P + ++ V E + + C V+G PKPE W +G V Sbjct: 221 AHLQRRREAMRAEGAPASPP-STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVT 279 Query: 456 RQEGSIEVYEDAGSHY-LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514 + VYEDA ++ L +L + D G Y+CTASN GQ T + V E A Sbjct: 280 EGRRHV-VYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-----TYSSVLVVVREPAV 333 Query: 515 SFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------L 568 F L+D V E + C V P W + ++ + G+ E L Sbjct: 334 PFKKRLQDLEVREKESATFLCEV-PQPSTEAAWFKEETRLW---ASAKYGIEEEGTERRL 389 Query: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628 +++ +D Y C V+ A +K RK+ Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTA------------------ 431 Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688 ++V D + + + V P V WL N E+ GT+H+L I + E Sbjct: 432 ---VRVGDTAMFCVELAVPVGP---VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485 Query: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEP 715 D G + AG+ +T V P Sbjct: 486 DVG----QVAFMAGDCQTSTQFCVSAP 508 Score = 103 bits (256), Expect = 2e-21 Identities = 84/337 (24%), Positives = 132/337 (39%), Gaps = 53/337 (15%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELH 569 AP F + K V G+D L C + G P P+++W + QP+ R + + L Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 629 I D D G Y C A NA+G+ + + V + A AP FL Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE------------AACAEQAPHFLLRP 116 Query: 630 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFP 687 + ++V +GS+ T +V G+P P V W +G + E + E+ G +L I+ P Sbjct: 117 TSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARP 176 Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL------------- 734 D GTY A N G A L V T S+P + TA+L Sbjct: 177 RDGGTYEVRAENPLGAASAAAALVVDSDAADT----ASRPGTSTAALLAHLQRRREAMRA 232 Query: 735 -------------------GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775 G+ +SC + G+P P W +DG+ + + H ++ Sbjct: 233 EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQE 292 Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 F L + + G Y N VG+ V ++++ Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329 Score = 100 bits (249), Expect = 1e-20 Identities = 189/808 (23%), Positives = 308/808 (38%), Gaps = 116/808 (14%) Query: 29 LTEAP-AFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87 +TE P +F P +++ E E + P V W ++G + +G + +G Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAI--AAQG 2217 Query: 88 TF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD-RFS 145 SL I+ D+G Y C+A + Q + + V+G + + V+++ G+ +F Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRVLAEDAGEIQFV 2273 Query: 146 APAVETRPSIW-GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204 A E+R + E P L + E G C+++ R QV W KG+ LQP Sbjct: 2274 AENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPG 2332 Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264 + + + L I V+ +D YTC +G SA+ ++ +S Sbjct: 2333 PKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVE-----EQSITIVR 2383 Query: 265 KATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324 + V + E+ + S+ + Q GG+ + R + Sbjct: 2384 GLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNV--GLEQEGTVHRLMLRRT 2441 Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSP-SGEERK--------RPA 375 C S T P + K+ SS L + + P L P +G E + RPA Sbjct: 2442 C--STMTGPVHFTVGKSRSSARLVVSDIPVVLTRP----LEPKTGRELQSVVLSCDFRPA 2495 Query: 376 PPRPATFPTRQPGLGSQ----DVVSKAANRRI----PMEG-----QRDSAFPKFESKPQS 422 P + P S+ + + A RI P + Q SA E ++ Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEA 2555 Query: 423 QEV-----------KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471 +EV E F CE+S EV W L G P+ + E+ H Sbjct: 2556 REVTVTGPLQDAEATEEGWASFSCELSH-EDEEVEWSLNGMPL-YNDSFHEISHKGRRHT 2613 Query: 472 LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531 L L + D+G ++ ++S S L+V V+ F L D + E Sbjct: 2614 LVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVV-----FLKALDDLSAEERGTL 2664 Query: 532 VLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588 LQC V P + W +G P AG L + D PED G YTC Sbjct: 2665 ALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----H 2719 Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 +G A V VH+ L V +K L ++V++G + +S Sbjct: 2720 VGSEETRARVRVHD----------LHVGITK--------RLKTMEVLEGESCSFECVLSH 2761 Query: 649 NPPPE-VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707 + +W G + S F ++G ++ L ++E P D G E S + ++ Sbjct: 2762 ESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG----EVVFSVRGLTSK 2817 Query: 708 AVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKD 764 A L V+E +P I KP + G+ V + C + AG P VHWL+D KA+ K Sbjct: 2818 ASLIVRE-----RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRK- 2868 Query: 765 TGHFEVLQNEDVFTLVLKKVQPWHAGQY 792 + ++V+ + LV++ AG+Y Sbjct: 2869 SQKYDVVCEGTMAMLVIRGASLKDAGEY 2896 Score = 100 bits (248), Expect = 2e-20 Identities = 166/761 (21%), Positives = 281/761 (36%), Gaps = 124/761 (16%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 L R + + GA A V + +VTW+++G+ ++S + ++ + T LV+ Sbjct: 1355 LAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEA-VGCTRRLVVQQA 1412 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSAPAVETRP 153 + D G+Y+CEA G ++++ L V FAK+ QPV + Sbjct: 1413 CQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKE--QPVHRE--------------- 1451 Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213 V + G SC++ + Q +V W K L S++V + Sbjct: 1452 ----------------VQAQAGASTTLSCEVA-QAQTEVMWYKDGKKLSFSSKVRMEAVG 1494 Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRETKA---T 267 + L + Q G Y+C +G +S L + + + + + RE +A T Sbjct: 1495 CTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGT 1550 Query: 268 NSDVRKEVTNV------------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315 ++ + EV +S SK+ +EA ++ + G + + + Sbjct: 1551 SATLSCEVAQAQTEVTWYKDGKKLSSSSKV-RMEAVGCTRRLVVQEAGQADAGEYSCKAG 1609 Query: 316 PPR--------ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPS 367 R E K+ K+ P + S++++ + A+ Q E G S Sbjct: 1610 DQRLSFHLHVAEPKVVFAKEQPAHR-EVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668 Query: 368 GEERKRPAPPRPATFPTRQPGLGSQDVVS-KAANRRIPMEGQRDSAFPKFESKPQSQE-- 424 + + A +Q G S +A +R+ P+ +P +E Sbjct: 1669 SSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREPL 1728 Query: 425 -VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 VKE++ + ++ V W +G +RR + E +H L + A+ DS Sbjct: 1729 VVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRH-ETASQGDTHTLTVHGAQVLDSA 1787 Query: 484 TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543 YSC A+GQ + +QVE EVA F +L+ G L C + Sbjct: 1788 IYSCRVG-AEGQ---DFPVQVE-----EVAAKFCRLLEPVCGELGGTVTLACEL-SPACA 1837 Query: 544 RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 + W ++ + E V L + ED G Y C Sbjct: 1838 EVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----------------- 1880 Query: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660 SR + S P F+ GLS + +G + T VS + V+W +G Sbjct: 1881 ----ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDG 1935 Query: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720 +Q SE F Q G HSL I ++ ED G T EA ++ + A L V+E Sbjct: 1936 ALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGAS----SSAALRVRE----AP 1987 Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 F K T SV + + P+P + W R+ AL Sbjct: 1988 VLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATAL 2027 Score = 97.4 bits (241), Expect = 1e-19 Identities = 189/859 (22%), Positives = 303/859 (35%), Gaps = 167/859 (19%) Query: 60 PEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118 P P++ W RN + G + G R LV+H V DRG + CE + ++T Sbjct: 2014 PWPELRWTRNATALAPGKNVEIHAEGAR--HRLVLHNVGFADRGFFGCETPDDKTQAKLT 2071 Query: 119 VELT-----------------------------VEGSFAKQ-------------LGQPVV 136 VE+ V+GS+ + + P+ Sbjct: 2072 VEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMH 2131 Query: 137 SKTLGDR---------FSAPAVETRPS-IWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186 + TL F A V T + E P F+ L VV E + C+++ Sbjct: 2132 TLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELS- 2190 Query: 187 RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246 RP V WLK V L+ ++++ + + L I+ D GVY C + A SA Sbjct: 2191 RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSA 2246 Query: 247 ELSIQGL------------DSANRSFVRETKATNSDVRKE---VTNVISKESKLDSLEAA 291 + +QG D+ FV E + + +R + VT V K+ ++E Sbjct: 2247 SVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKI-AMEKH 2305 Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSP-RTAPQTPVLQKTSSSITLQAA 350 C + W SQ P K E D R + V + + T A Sbjct: 2306 RGVLECQVSRASAQVRWFKGSQELQPGP-KYELVSDGLYRKLIISDVHAEDEDTYTCDAG 2364 Query: 351 RVQPEPR--APGLGVLSPSGEERKRPAPPRPATF------PTRQP--------------- 387 V+ + + G + P PA F P+ +P Sbjct: 2365 DVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGN 2424 Query: 388 -GLGSQDVVSKAANRRI--PMEG--------QRDSA------FPKFESKPQSQEV-KENQ 429 GL + V + RR M G R SA P ++P + +E Q Sbjct: 2425 VGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQ 2484 Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489 +V C+ PK V W+ + TP+ E ++ + L +L+ D+G Y C A Sbjct: 2485 SVVLSCDFRPAPKA-VQWYKDDTPLSPSE-KFKMSLEGQMAELRILRLMPADAGVYRCQA 2542 Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 +A S + VE V P L+D E C + + W L Sbjct: 2543 GSAHS----STEVTVEAREVTVTGP-----LQDAEATEEGWASFSCELSHED-EEVEWSL 2592 Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609 NG P+ Y S E L + + +VS SA + V K Sbjct: 2593 NGMPL-YNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRVK------ 2645 Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 PV +FL+ L DL + + + +VS +P V+W +G ++ S+ + Sbjct: 2646 ----PV--------VFLKALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKY 2692 Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729 F L + +V PED G YTC G T+A + V + H G + ++ Sbjct: 2693 DFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARVRVHDLHVG----ITKRLKT 2744 Query: 730 VTASLGQSVLISCAI----AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785 + G+S C + A DP W GK + + F+ + + LV+++ Sbjct: 2745 MEVLEGESCSFECVLSHESASDP---AMWTVGGKTV-GSSSRFQATRQGRKYILVVREAA 2800 Query: 786 PWHAGQYEILLKNRVGECS 804 P AG+ ++ + S Sbjct: 2801 PSDAGEVVFSVRGLTSKAS 2819 Score = 92.8 bits (229), Expect = 3e-18 Identities = 67/245 (27%), Positives = 112/245 (45%), Gaps = 10/245 (4%) Query: 19 VDPSRVDSMPLTEA-PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77 V P + S+ ++A P F+ +N +++G F+ V G P P V W ++G+ + Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170 Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137 ++++ +G L+I AV D G Y C A N G EL V+ + + + Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLT-STDYDTAADA 5229 Query: 138 KTLGDRFSAPA-VETRPSIWGECP------PKFATKLGRVVVKEG-QMGRFSCKITGRPQ 189 FSA + +R E P+ +L + V G ++ +F K+ G P Sbjct: 5230 TESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPA 5289 Query: 190 PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249 P++ W K PL SA + +++K + LEI V ++D G Y + N G A SA L Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349 Query: 250 IQGLD 254 ++G D Sbjct: 5350 VRGPD 5354 Score = 91.7 bits (226), Expect = 6e-18 Identities = 59/214 (27%), Positives = 91/214 (42%), Gaps = 15/214 (7%) Query: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676 P AP FL V G T++ Q+ GNP P+V W + + F Q G Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD 63 Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGE--------VRTQAVLTVQEPHDGTQPWFISKPR 728 + L I ++ D+G Y C A N+ GE V +A Q PH F+ +P Sbjct: 64 LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH------FLLRPT 117 Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPW 787 S+ G C + G P P V W +DG+ L + G V + + L ++ +P Sbjct: 118 SIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR 177 Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821 G YE+ +N +G S +L++ + +A R Sbjct: 178 DGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211 Score = 90.9 bits (224), Expect = 1e-17 Identities = 103/412 (25%), Positives = 150/412 (36%), Gaps = 37/412 (8%) Query: 118 TVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS---IWGECPPKFATKLGRVVVKE 174 T+ + VE +Q G V + AP V P + + P F T+L V++ Sbjct: 5081 TLGIGVEIKLVEQ-GPRRVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQD 5139 Query: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTC 233 G F C +TG+P P V W K L+ ++E + G L I V D+GVY C Sbjct: 5140 GYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRC 5199 Query: 234 LVVNGSGKASMSAELSIQ--------GLDSANRSFVRETKATNSDVRKEVTNVISKESKL 285 L N G +S AEL + D+ S + S +E T + E +L Sbjct: 5200 LAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTESTTDEGQL 5259 Query: 286 DSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDS-PRTAPQTPVLQKTSSS 344 + + + R P P +L KD P TA + Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAP----RLYWFKDGQPLTASAHIRMTDKKIL 5315 Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP 404 TL+ V E +S + A A R P + S + +P Sbjct: 5316 HTLEIISVTREDSGQYAAYISNA-----MGAAYSSARLLVRGPDEPEEKPASDVHEQLVP 5370 Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-----VRRQEG 459 P+ + ++VK+ ++ F +V G P P V W E + Sbjct: 5371 ---------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTP 5421 Query: 460 SIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME 511 V A H L LL + GTY+C ASNA GQ CS +L V L +E Sbjct: 5422 GYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473 Score = 87.0 bits (214), Expect = 2e-16 Identities = 67/233 (28%), Positives = 102/233 (43%), Gaps = 31/233 (13%) Query: 31 EAPAFILPPRNLCIKEGAT-AKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRGT 88 + P + R+L + G AKF+ +V+GYP P++ W ++GQP+T+ + D I T Sbjct: 5258 QLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHT 5317 Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148 ++ +V ED G+Y +N GA + L V G + PA Sbjct: 5318 LEII--SVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE--------------EKPA 5361 Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV--------P 200 + + PP+ + VK+G FS K+ GRP P V WL+ P Sbjct: 5362 SDVHEQL---VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418 Query: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253 P V+ S + VL V + G YTC+ N +G+A SA L + GL Sbjct: 5419 DTPGYTVASSAQQHSLVL--LDVGRQHQGTYTCIASNAAGQALCSASLHVSGL 5469 Score = 85.1 bits (209), Expect = 6e-16 Identities = 163/756 (21%), Positives = 268/756 (35%), Gaps = 126/756 (16%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106 G A+FE V W+++G + G L + LV V +D G Y+C Sbjct: 812 GGPAQFECET-SEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870 Query: 107 EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166 S F ++ +P V F+ + R Sbjct: 871 RVGEDSV------------DFRLRVSEPKVV------FAKEQLARR-------------- 898 Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226 ++ + G SC++ + Q +VTW K L S++V + + L + Q Sbjct: 899 --KLQAEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQA 955 Query: 227 DVGVYTCLVVNGSGKASMSAELSIQ------GLDSANRSFVRETKATNSDVRKEVTNVIS 280 D G Y+C +G +S L ++ D S V+ ++ + EV + Sbjct: 956 DAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT 1011 Query: 281 -----KESKL--DSLEAAAKSKNCSS----PQRGGSPPWAANSQPQPPRES-KLESCKDS 328 K+ K SL+ ++K C Q G + + + + R S +L + Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPK 1071 Query: 329 PRTAPQTPVLQKT------SSSITLQAARVQPEPR--APGLGVLSPSGEERKRPAPPRPA 380 A + V + S+ ++ + A+ Q E G + S S + R Sbjct: 1072 MMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRL 1131 Query: 381 TFPTRQPGLGSQDVVS-KAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTVKFRCE 436 P Q G S +A +R+ + F K +S + + T CE Sbjct: 1132 VLP--QAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCE 1189 Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V+ P+ EV W+ +G + + + + L + + D+G YSC A + Sbjct: 1190 VAQ-PQTEVTWYKDGKKLS-SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSF 1247 Query: 497 SCSWTLQVERLAVMEVAPSFSS---VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553 +L + E F+ V + G L C V +TW +G+ Sbjct: 1248 ---------QLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKK 1297 Query: 554 IQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610 + + R + +L +Q A D G YTC A ++ Sbjct: 1298 LSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA-------------------GGQRLS 1338 Query: 611 YLLPVAPSKPTAPIFLQGLSDLKVMD--GSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668 + L V S+P A + L+ KV G+ T++ +V+ EV W +G ++ S Sbjct: 1339 FHLDV--SEPKAVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSK 1395 Query: 669 FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFIS 725 E G L +Q+ DTG Y+CE AG R L V EP QP Sbjct: 1396 VRMEAVGCTRRLVVQQACQADTGEYSCE----AGGQRLSFSLDVAEPKVVFAKEQP---- 1447 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 R V A G S +SC +A V W +DGK L Sbjct: 1448 VHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKKL 1482 Score = 82.8 bits (203), Expect = 3e-15 Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 32/239 (13%) Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83 +D + AP F+ P+ + G A ++ G P PQV+W ++ QP+ +G RF L Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL-A 59 Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143 + L I + D G+Y C A N G V L V+ A Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA--------------- 104 Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202 E P F + + V+EG F C++ G P+P V+W K L + Sbjct: 105 ------------CAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGE 152 Query: 203 PSA-RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI--QGLDSANR 258 P RV V E L I D G Y N G AS +A L + D+A+R Sbjct: 153 PDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211 Score = 82.8 bits (203), Expect = 3e-15 Identities = 166/799 (20%), Positives = 279/799 (34%), Gaps = 143/799 (17%) Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE--E 99 +C KE +A VR P + RN + T G L C + + HE Sbjct: 3697 MCGKERTSAMLT--VRAMPSKFIEGLRN-EEATEGDTATLWCELSKAAPVEWRKGHETLR 3753 Query: 100 DRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158 D +++ Q+ V+ G ++ GQ S TL R Sbjct: 3754 DGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVR--------------A 3799 Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218 P +F + +EG C+++ V W KG+ L+ R S+ + L Sbjct: 3800 LPARFIEDVKNQEAREGATAVLQCELS--KAAPVEWRKGSETLRGGDRYSLRQDGTRCEL 3857 Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV 278 +IHG++ D G Y+C+ G+ SA L++ +A R+ + ++ Sbjct: 3858 QIHGLSVADTGEYSCV----CGQERTSATLTV--------------RAPQPVFREPLQSL 3899 Query: 279 ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESC----------KDS 328 ++E +L+ + G AN + RE +L+ C ++ Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGR----REPRLQGCTAELVLQDLQRED 3955 Query: 329 PRTAPQTPVLQKTSSSITLQAARV------QPEPRAPG--------LGVLSPSGEERKRP 374 T Q TS+++T+ AA V Q + G L S E RK Sbjct: 3956 TGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGS 4015 Query: 375 APPRP-ATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF-----------------PKF 416 P A + Q G ++ +V R + E D PKF Sbjct: 4016 LQLFPCAKYQMVQDGAAAELLV-----RGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKF 4070 Query: 417 ESKPQSQEVKENQTVKFRCEVSGIPKPEVA-WFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 +++ QS E + + C++S V W EG + E+ + L + Sbjct: 4071 KTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGP-KYEMRSQGATRELLIH 4129 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 + +D+G Y+C + S L V E + L D V +D C Sbjct: 4130 QLEAKDTGEYACVTGGQKTAAS---------LRVTEPEVTIVRGLVDAEVTADEDVEFSC 4180 Query: 536 SVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-----LHIQDALPEDHGTYTCLAENALG 590 V + W L G P+Q + E V + L ++ PED GT + LG Sbjct: 4181 EVSRAGATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLG 4235 Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650 + SA +TV + + L+ L D+++ +G + ++S Sbjct: 4236 NHASSAQLTVRAPEVT------------------ILEPLQDVQLSEGQDASFQCRLSRAS 4277 Query: 651 PPEVIWLHNGNEIQESE--DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708 E W G +Q +E D EQ GT H L + +V ED GT + + E + + Sbjct: 4278 GQEARWALGGVPLQANEMNDITVEQ-GTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKV 4336 Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGH 767 + + +V A G L C ++ WL D + + + Sbjct: 4337 T---------AKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAE 4387 Query: 768 FEVLQNEDVFTLVLKKVQP 786 +N L+LK ++P Sbjct: 4388 VVFFENGLRHLLLLKNLRP 4406 Score = 82.0 bits (201), Expect = 5e-15 Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 9/199 (4%) Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 681 P F + L+D G V + +V+G P P + W +G +Q + E +L Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741 + + D+G Y C A ++AG T + VQ P P F++K R+ G+ + Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128 Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ--NEDVFTLVLKKVQPWHAGQYEILLKNR 799 C I G P+P + W +DG AL F+ L + LV++ G YE L NR Sbjct: 6129 CTIEGAPYPQIRWYKDG-ALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187 Query: 800 VGECSCQVSLMLQNSSARA 818 +G L +Q+ +A Sbjct: 6188 LGSARASAELRIQSPMLQA 6206 Score = 79.3 bits (194), Expect = 3e-14 Identities = 156/687 (22%), Positives = 265/687 (38%), Gaps = 117/687 (17%) Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120 + +V W+++G+ ++ + ++ + T LV+ + G+Y+CEA G+++++ Sbjct: 1470 QTEVMWYKDGKKLSFSSKVRMEA-VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFH 1524 Query: 121 LTV---EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQM 177 L V + FAK+ QP + V + G Sbjct: 1525 LHVAEPKAVFAKE--QPASRE-------------------------------VQAEAGTS 1551 Query: 178 GRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237 SC++ + Q +VTW K L S++V + + L + Q D G Y+C Sbjct: 1552 ATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA-- 1608 Query: 238 GSGKASMSAELSIQGL-----DSANRSFVRETKAT---NSDVRKEVTNV--------ISK 281 G + S ++ + A+R E A+ + +V + T V +S Sbjct: 1609 GDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668 Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES------KLESCKDSPRTAPQT 335 SK+ +EA ++ Q G + + + R S +LE + S R + Sbjct: 1669 SSKV-RVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEP-QISERPCRRE 1726 Query: 336 PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGL-GSQDV 394 P++ K I L A P A + L E R+ + T + G+Q + Sbjct: 1727 PLVVKEHEDIILTATLATPS--AATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVL 1784 Query: 395 VSKAANRRIPMEGQR-----DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFL 449 S + R+ EGQ + KF + + TV CE+S EV W Sbjct: 1785 DSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACA-EVVWRC 1843 Query: 450 EGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509 T +R + ++ + L +L R D+G Y C + + S T+ V R+ Sbjct: 1844 GNTQLRVGK-RFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD--DHTSAQLTVSVPRVV- 1899 Query: 510 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAE 567 F S L EG + QC V + V + W +G +Q + + ++G + Sbjct: 1900 -----KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASH 1953 Query: 568 -LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626 L I D + ED G T AE A S SA + V E PV +F Sbjct: 1954 SLTISDLVLEDAGQITVEAEGA----SSSAALRVREA----------PV--------LFK 1991 Query: 627 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686 + L V + S VT+ V+++ P PE+ W N + ++ G +H L + V Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050 Query: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 D G + CE + +TQA LTV+ Sbjct: 2051 FADRGFFGCE----TPDDKTQAKLTVE 2073 Score = 79.0 bits (193), Expect = 4e-14 Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 13/250 (5%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS--QEGSLCS 1154 AP F +LQ+ V +G + C V+ P ++ W +GK L+ +++ Q+G Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG-HQ 5183 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + I +P D G+Y+C+A+N G + ++ VD +T A +S S+ + Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243 Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTGTQPITCTWMK 1273 E + T ++ PQ+++ D +V G + F KV G W K Sbjct: 5244 SREQEGT-------ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296 Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333 + + S H+++ + + L I++ +E G Y + N +G+ + L +V PD Sbjct: 5297 DGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPDE 5355 Query: 1334 PAGTPCASDI 1343 P P ASD+ Sbjct: 5356 PEEKP-ASDV 5364 Score = 78.2 bits (191), Expect = 7e-14 Identities = 153/756 (20%), Positives = 264/756 (34%), Gaps = 107/756 (14%) Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96 L R L + GA+A V + +VTW+++G+ ++S + ++ T LV+ Sbjct: 895 LARRKLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEA-TGCTRRLVVQQA 952 Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156 + D G+Y+CEA G ++++ L V+ +P V Sbjct: 953 GQADAGEYSCEA----GGQRLSFHLDVK--------EPKVVFA----------------- 983 Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216 K V + G SC++ + Q +V W K L S +V V K + Sbjct: 984 -----KDQVAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRR 1037 Query: 217 VLEIHGVNQDDVGVYTCLVVN---------GSGKASMSAELSIQGLDSANRSFVRETKAT 267 L + + D G Y+C K + E S+ A Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCE 1097 Query: 268 NSDVRKEVT-----NVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-K 321 + + EVT +S SK+ +E ++ PQ G + + + R S Sbjct: 1098 VAQAQTEVTWYKDGKKLSSSSKV-GMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFH 1156 Query: 322 LESCKDSPRTAPQTPVLQK------TSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375 L + A + V + T++ ++ + A+ Q E G S + + Sbjct: 1157 LHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEV 1216 Query: 376 PPRPATFPTRQPGLGSQDVVS-KAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTV 431 +Q G S +A +R+ + + + F K + + + Sbjct: 1217 KGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASA 1276 Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491 CEV+ + EV W+ +G + + + L + +A D+G Y+C A Sbjct: 1277 TLSCEVAQ-AQTEVTWYKDGKKL-SSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGG 1334 Query: 492 AQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551 +LS + + + + V + I L C V +TW +G Sbjct: 1335 Q--RLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIA----TLSCEVAQAQT-EVTWYKDG 1387 Query: 552 QPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608 + + + R L +Q A D G Y+C A ++ Sbjct: 1388 KKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA-------------------GGQR 1428 Query: 609 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668 + L VA K +++ G+ T++ +V+ EV+W +G ++ S Sbjct: 1429 LSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKKLSFSSK 1487 Query: 669 FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFIS 725 E G L +Q+ G Y+CE AG R L V EP QP Sbjct: 1488 VRMEAVGCTRRLVVQQAGQAVAGEYSCE----AGSQRLSFHLHVAEPKAVFAKEQP---- 1539 Query: 726 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 R V A G S +SC +A V W +DGK L Sbjct: 1540 ASREVQAEAGTSATLSCEVA-QAQTEVTWYKDGKKL 1574 Score = 78.2 bits (191), Expect = 7e-14 Identities = 172/822 (20%), Positives = 308/822 (37%), Gaps = 150/822 (18%) Query: 60 PEPQ-VTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQV 117 P P+ V W+++ P++ +F + + G + L I + D G Y C+A + + +V Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMS--LEGQMAELRILRLMPADAGVYRCQAGSAHSSTEV 2551 Query: 118 TVE---LTVEG-------------SFAKQL------------GQPVVSKTLGD------- 142 TVE +TV G SF+ +L G P+ + + + Sbjct: 2552 TVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611 Query: 143 ----------------RFSAPAVETRPSIWGECPPK-FATKLGRVVVKEGQMGRFSCKIT 185 R S+ V T + P F L + +E C+++ Sbjct: 2612 HTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS 2671 Query: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245 P+ V W K V L PS + G + L +H V+ +D G+YTC V G Sbjct: 2672 D-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHV----GSEETR 2726 Query: 246 AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-- 303 A + + L + + K + + E + S E ++ S P Sbjct: 2727 ARVRVHDL--------------HVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTV 2772 Query: 304 GSPPWAANSQPQPPRESK---LESCKDSPRTAPQTPV----LQKTSSSITLQ--AARVQP 354 G ++S+ Q R+ + L + +P A + L +S I + AA ++P Sbjct: 2773 GGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKP 2832 Query: 355 ---EPRAPGLGV-----LSPSGEE----RKRPAPPRPATFPTRQPGLGSQDVVSKAANR- 401 + APG V LS +G + R A + + G + V+ A+ + Sbjct: 2833 LEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKD 2892 Query: 402 ----RIPMEGQRDSAFPKFESKPQ-------SQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 +E + +A E K + +V+E T F C+ P V W + Sbjct: 2893 AGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTW-RK 2950 Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510 G R G + ++ + L + DS TY+C AQ + +Q R+ ++ Sbjct: 2951 GLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQL--LVQGRRVHII 3008 Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570 E L+D V EG +C + + W L+ P+ EL+ Sbjct: 3009 ED-------LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLH---------ANELNE 3052 Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 DA P G Y L L Q++ T++ + +++ L V KP+ +F + L+ Sbjct: 3053 IDAQP---GGYHVL---TLRQLALKDSGTIYFEAGDQRASAALRVT-EKPS--VFSRELT 3103 Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690 D + +G +T+ + S P V W +G ++ S G + L I +D+ Sbjct: 3104 DATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDS 3162 Query: 691 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 750 G Y CE AG + +++ V F + + G + + C ++ P Sbjct: 3163 GRYKCE----AGGACSSSIVRVH----ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP 3214 Query: 751 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792 V W G + + + + Q + LV++ ++P +G+Y Sbjct: 3215 -VKWCY-GNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254 Score = 76.6 bits (187), Expect = 2e-13 Identities = 65/234 (27%), Positives = 97/234 (41%), Gaps = 43/234 (18%) Query: 23 RVDSMPLTEAPAFILPP----RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78 R ++M APA PP R + EG A+ V G P+P+ W ++GQ +T G R Sbjct: 226 RREAMRAEGAPAS--PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 ++ + F L I + DRG YTC A+N G +V + V Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR-------------- 329 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 PAV F +L + V+E + F C++ +P + W K Sbjct: 330 -------EPAVP------------FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEE 369 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252 L SA+ + E+ + L + V+ DD VY C GS AEL++QG Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTV---AELAVQG 420 Score = 75.9 bits (185), Expect = 4e-13 Identities = 156/751 (20%), Positives = 273/751 (36%), Gaps = 117/751 (15%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYT 105 GA+A V + +V W+++G+ ++S + ++ G R LV+ + D G Y+ Sbjct: 997 GASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRR--LVVQQAGKTDAGDYS 1053 Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFAT 165 CEA G R S T P + K + Sbjct: 1054 CEAR-------------------------------GQRVSFRLHITEPKMMFA---KEQS 1079 Query: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQ 225 V + G SC++ + Q +VTW K L S++V + K + L + + Sbjct: 1080 VHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGK 1138 Query: 226 DDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRETKAT-------NSDVRKEV 275 D G Y+C +G +S L I +G+ + +S E +A + +V + Sbjct: 1139 ADAGEYSC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQ 1194 Query: 276 TNV--------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCK 326 T V +S SK+ +E ++ Q G + + + R S +L + Sbjct: 1195 TEVTWYKDGKKLSSSSKV-RMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITE 1253 Query: 327 DSPRTAPQTPVLQKT------SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA 380 A + V + S++++ + A+ Q E G S + + A Sbjct: 1254 PKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMR 1313 Query: 381 TFPTRQPGLGSQ-DVVSKAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTVKFRCE 436 +Q G + +A +R+ + + F K + + + + CE Sbjct: 1314 QLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCE 1373 Query: 437 VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496 V+ + EV W+ +G + + + + L + +A D+G YSC A + L Sbjct: 1374 VAQA-QTEVTWYKDGKKLS-SSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQR--L 1429 Query: 497 SCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY 556 S S + ++ + P V ++ G L C V + W +G+ + + Sbjct: 1430 SFSLDVAEPKVVFAKEQP----VHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSF 1484 Query: 557 ARSTCEAGVA---ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613 + V L +Q A G Y+C A S++ + L Sbjct: 1485 SSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA-------------------GSQRLSFHL 1525 Query: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673 VA K +++ G+ T++ +V+ EV W +G ++ S E Sbjct: 1526 HVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEA 1584 Query: 674 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSV 730 G L +QE D G Y+C+ AG+ R L V EP QP R V Sbjct: 1585 VGCTRRLVVQEAGQADAGEYSCK----AGDQRLSFHLHVAEPKVVFAKEQP----AHREV 1636 Query: 731 TASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 A G S +SC +A V W +DGK L Sbjct: 1637 QAEAGASATLSCEVA-QAQTEVTWYKDGKKL 1666 Score = 75.5 bits (184), Expect = 5e-13 Identities = 161/754 (21%), Positives = 264/754 (35%), Gaps = 184/754 (24%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG-TFSL 91 P F P ++L +EG+TA + + P V W + G + + GR + ++G T L Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGR--REPRLQGCTAEL 3946 Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTV---------------------------- 123 V+ + ED G+YTC T GS A T+ +T Sbjct: 3947 VLQDLQREDTGEYTC--TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSR 4004 Query: 124 ------------------------EGSFAKQLGQPVVSKTLGD-RFSAPAVETRPSIWGE 158 +G+ A+ L + V + GD ++ S+ Sbjct: 4005 AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVR 4064 Query: 159 CP-PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT-WLKGNVPLQPSARVSVSEKNGMQ 216 P PKF T+L + + G + R C+++ V WLK V L + + + + Sbjct: 4065 VPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124 Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVT 276 L IH + D G Y C V G K + S +R T+ + VR V Sbjct: 4125 ELLIHQLEAKDTGEYAC--VTGGQKTAAS---------------LRVTEPEVTIVRGLVD 4167 Query: 277 NVISKESKLDSLEAAAKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKD----SPRT 331 ++ + ++ +C + G + W P E + +D + R Sbjct: 4168 AEVTADEDVEF--------SCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRL 4219 Query: 332 APQTPVLQKT-SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390 TP T S + A+ Q RAP + +L P Sbjct: 4220 KGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP------------------------ 4255 Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 QDV EGQ D++F S+ QE R + G+P Sbjct: 4256 LQDVQLS--------EGQ-DASFQCRLSRASGQEA--------RWALGGVP--------- 4289 Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510 ++ E + E H L L K D+GT S +CS Q++ A Sbjct: 4290 ---LQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVG------TCSSEAQLKVTAKN 4340 Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST----CEAGVA 566 V L++ +EG + + +C + V TWLL+ +P+ + + E G+ Sbjct: 4341 TVVRG----LENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLR 4396 Query: 567 E-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 625 L +++ P+D T LA G + SA++TV + Sbjct: 4397 HLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE------------------I 4434 Query: 626 LQGLSDLKVMDGSQVTMTVQVS-GNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQ 683 L+ L + V G+Q T +S P E W NG +Q + D+ G+ H+L ++ Sbjct: 4435 LEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLR 4494 Query: 684 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 P G T ++ R + P D Sbjct: 4495 SAQPHHAGEVTFACRDAVASARLTVLGLPDPPED 4528 Score = 73.6 bits (179), Expect = 2e-12 Identities = 107/500 (21%), Positives = 181/500 (36%), Gaps = 101/500 (20%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR-VSVSEKNGMQVL 218 PP F +L + G+ + +C++TG P+P ++W K +Q + + + +G L Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072 Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT----NSDVRKE 274 + + D G Y C + +G S ++ +Q FV + +A+ D + Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----VPPRFVNKVRASPFVEGEDAQFT 6128 Query: 275 VT---------------NVISKESKLDSLE------------AAAKSK----NCSSPQRG 303 T +++ +K +L AA+K C R Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188 Query: 304 GSPPWAANSQPQPPRESKLESC-KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLG 362 GS +A + Q P E C ++ A + L++ +T R+ P+APG Sbjct: 6189 GSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLG-PKAPG-- 6245 Query: 363 VLSPSGEERKRPAP-PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421 PS + P P PR A P Q V + +P + E +P+ Sbjct: 6246 ---PSTGDLTGPGPCPRGA--PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPE 6300 Query: 422 SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481 + + TV R E + P G+ E+ D SH +++ T+ Sbjct: 6301 AIARAQEWTVPIRMEGAAWPGA---------------GTGELLWDVHSH---VVRETTQR 6342 Query: 482 SGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541 + TY ++ PS ++D G + + G P Sbjct: 6343 TYTYQAIDTHTARP------------------PSMQVTIEDVQAQTGGTAQFEAIIEGDP 6384 Query: 542 VPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596 P +TW + +Q ST E L ++ +D G YTCLA+N GQV C A Sbjct: 6385 QPSVTWYKDS--VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 6442 Query: 597 WVTV--------HEKKSSRK 608 + V EK+S R+ Sbjct: 6443 ELLVLGGDNEPDSEKQSHRR 6462 Score = 71.2 bits (173), Expect = 9e-12 Identities = 36/92 (39%), Positives = 51/92 (55%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I+ V D Y C A NS+G ++ AEL V+ Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217 Score = 68.6 bits (166), Expect = 6e-11 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Query: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1861 E K P FS T D E G A R +C + D W KD + + RH ID Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950 Query: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1913 DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++ Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005 Score = 68.2 bits (165), Expect = 7e-11 Identities = 138/635 (21%), Positives = 245/635 (38%), Gaps = 100/635 (15%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 P +F KL EG C+++ V W KG+ L+ R + + M L+ Sbjct: 3273 PAQFIGKLRNKEATEGATATLRCELS--KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQ 3330 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279 I G+ D Y+C+ G+ SA L+I+ + + F+ + S + + Sbjct: 3331 IRGLAMVDAAEYSCV----CGEERTSASLTIRPMPA---HFIGRLRHQES-IEGATATLR 3382 Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVL- 338 + SK +E ++ R +S Q +L+ C + A + + Sbjct: 3383 CELSKAAPVEWRKGRESLRDGDR--------HSLRQDGAVCELQICGLAVADAGEYSCVC 3434 Query: 339 --QKTSSSITLQA------ARVQPEPRAPG--------LGVLSPSGEERKRPAPPRPA-T 381 ++TS+++T++A ++ E G L ++P E RK P R Sbjct: 3435 GEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDR 3493 Query: 382 FPTRQPGLGSQ----DVVSKAANRRIPMEGQ-RDSAFPKFESKPQS--QEVKENQ----- 429 + RQ G + + A + + GQ R SA + P ++VK + Sbjct: 3494 YILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPARFIEDVKNQEAREGA 3553 Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489 T +CE++ E + +G+ R + +D L + D+G YSC Sbjct: 3554 TAVLQCELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC 3610 Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 GQ S L V L + F+ L++ EG VL+C + + + + W Sbjct: 3611 ----GQERTSAMLTVRALPI-----KFTEGLRNEEATEGATAVLRCEL--SKMAPVEWWK 3659 Query: 550 NGQPIQYA--RSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 606 + ++ S + G EL I+ + ED G Y C+ G+ SA +TV Sbjct: 3660 GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR----- 3710 Query: 607 RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES 666 PSK F++GL + + +G T+ ++S P E W +++ Sbjct: 3711 --------AMPSK-----FIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDG 3755 Query: 667 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 726 + Q G++ L I+ + D G Y+C G+ RT A LTV+ FI Sbjct: 3756 DRHSLRQDGSRCELQIRGLAVVDAGEYSC----VCGQERTSATLTVR----ALPARFIED 3807 Query: 727 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761 ++ A G + ++ C ++ V W + + L Sbjct: 3808 VKNQEAREGATAVLQCELS--KAAPVEWRKGSETL 3840 Score = 67.4 bits (163), Expect = 1e-10 Identities = 60/243 (24%), Positives = 96/243 (39%), Gaps = 22/243 (9%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154 AP F + + V EG + +C+V P + W+ +G+ L + + + G + Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168 Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 + I A P D G Y+ A+N G A + + VD A + RP +S +L Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD--------TASRPGTSTAALL 220 Query: 1215 G--TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272 ++ + AP +PP V G+ L VTG W Sbjct: 221 AHLQRRREAMRAEGAPASPPSTG--------TRTCTVTEGKHARLSCYVTGEPKPETVWK 272 Query: 1273 KFRKQIQES-EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331 K + + E H+ E+++ L IL +Q G YT N +G + V L VV +P Sbjct: 273 KDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREP 331 Query: 1332 DPP 1334 P Sbjct: 332 AVP 334 Score = 67.0 bits (162), Expect = 2e-10 Identities = 62/229 (27%), Positives = 82/229 (35%), Gaps = 25/229 (10%) Query: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491 KF+ +V G P P + WF +G P+ I + + H L ++ DSG Y+ SN Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPL-TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337 Query: 492 AQGQLSCSWTLQVERLAVME-----------VAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540 A G S L V E V P V +G V G Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397 Query: 541 PVPRITWLLN---------GQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591 PVP + WL G A L + D + GTYTC+A NA GQ Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457 Query: 592 VSCSAWVTV----HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636 CSA + V ++ + E L+ T I QGL D Sbjct: 5458 ALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFAD 5506 Score = 65.5 bits (158), Expect = 5e-10 Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 13/151 (8%) Query: 114 ARQVTVELTVEGSFAKQLG---------QPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164 A++ TV + +EG+ G VV +T ++ A++T + PP Sbjct: 6305 AQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTAR----PPSMQ 6360 Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224 + V + G +F I G PQP VTW K +V L S R+S ++ L + V Sbjct: 6361 VTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 6420 Query: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255 D GVYTCL N G+ AEL + G D+ Sbjct: 6421 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 6451 Score = 63.9 bits (154), Expect = 1e-09 Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P TI D++ G A+F+ IEG P P V W+KD + +S E SL+ Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLV 6415 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 + V D YTC A N+ G+ C AEL+V G+ E + E++ Sbjct: 6416 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV---LGGDNEPDSEKQ 6458 Score = 63.5 bits (153), Expect = 2e-09 Identities = 25/92 (27%), Positives = 49/92 (53%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 + + G D +Y C A ++ G + +++V+ Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105 Score = 62.0 bits (149), Expect = 5e-09 Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Query: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 1865 V P F +R VEG A+F C IEG P P++ W+KD + FQ + G Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165 Query: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901 L+I +D Y C+ VN LG A +AEL +++ Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201 Score = 61.2 bits (147), Expect = 9e-09 Identities = 75/376 (19%), Positives = 137/376 (36%), Gaps = 38/376 (10%) Query: 413 FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472 F K + + + + + CEV+ + EV W+ +G + + + + L Sbjct: 1442 FAKEQPVHREVQAQAGASTTLSCEVAQA-QTEVMWYKDGKKLSFSS-KVRMEAVGCTRRL 1499 Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 + +A +G YSC A + + LS + + + P+ V + G Sbjct: 1500 VVQQAGQAVAGEYSCEAGSQR--LSFHLHVAEPKAVFAKEQPASREVQAEA----GTSAT 1553 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA---ELHIQDALPEDHGTYTCLAENAL 589 L C V +TW +G+ + + V L +Q+A D G Y+C Sbjct: 1554 LSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC------ 1606 Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 K ++ + L VA K +++ G+ T++ +V+ Sbjct: 1607 -------------KAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVA-Q 1652 Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 EV W +G ++ S E G L +Q+ D G Y+CEA R Sbjct: 1653 AQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLH-- 1710 Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 + EP +P + + + ++++ +A TV WL+DG + + H E Sbjct: 1711 VAELEPQISERP---CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRH-E 1766 Query: 770 VLQNEDVFTLVLKKVQ 785 D TL + Q Sbjct: 1767 TASQGDTHTLTVHGAQ 1782 Score = 61.2 bits (147), Expect = 9e-09 Identities = 86/385 (22%), Positives = 152/385 (39%), Gaps = 62/385 (16%) Query: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475 F + + QE E T RCE+S E + +G R + +D L + Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAPVE---WRKGRESLRDGDRHSLRQDGAVCELQIC 3420 Query: 476 KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535 D+G YSC G+ S TL V+ L F+ L++ +EG +L C Sbjct: 3421 GLAVADAGEYSCVC----GEERTSATLTVKALPA-----KFTEGLRNEEAVEGATAMLWC 3471 Query: 536 SVRGTPVPRITW------LLNGQP--IQYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587 + + V + W L +G ++ + CE + L + DA G Y C+ Sbjct: 3472 EL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADA-----GEYLCVC-- 3522 Query: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647 GQ SA +T+ LP F++ + + + +G+ + +++ Sbjct: 3523 --GQERTSATLTIRA----------LPAR--------FIEDVKNQEAREGATAVLQCELN 3562 Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707 P E W +++ + + Q GT+ L I+ + DTG Y+C G+ RT Sbjct: 3563 SAAPVE--WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSC----VCGQERTS 3616 Query: 708 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 A+LTV+ F R+ A+ G + ++ C ++ V W + G +D Sbjct: 3617 AMLTVR----ALPIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWK-GHETLRDGDR 3669 Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQY 792 + Q+ L ++ + AG+Y Sbjct: 3670 HSLRQDGARCELQIRGLVAEDAGEY 3694 Score = 61.2 bits (147), Expect = 9e-09 Identities = 82/341 (24%), Positives = 117/341 (34%), Gaps = 35/341 (10%) Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR---- 558 +V + + P FS D G L+C V R WL +G + R Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946 Query: 559 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618 G L I D G YTC N GQV+ SA V V +S +S + + Sbjct: 4947 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDA 5006 Query: 619 KPTAPIFLQGL----SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF---HF 671 A L L S +V D + P W +E E F F Sbjct: 5007 FRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW----QTYREDEHFICIRF 5062 Query: 672 EQ--RGTQHSLCIQEVFPE----------DTGTYTCEAWNSAGEVRTQAVLTVQEP---- 715 E Q QE+F + G E S T A + EP Sbjct: 5063 EALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISK---ETPAPVVPPEPLPSL 5119 Query: 716 -HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNE 774 P F+++ ++ G V C + G P P+V W +DGK L +D + + Sbjct: 5120 LTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQ 5179 Query: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815 L++ V P G Y L +N +G S + L + +S Sbjct: 5180 GGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTS 5220 Score = 60.5 bits (145), Expect = 2e-08 Identities = 56/262 (21%), Positives = 103/262 (39%), Gaps = 39/262 (14%) Query: 1079 RGHAGTTDNE--KRSESQGTAPAFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNG 1135 +G+ + + E + + +G P ++L+D+ VA G +L Q +V P + W +G Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298 Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195 + L + I ++ + L ++ I ED G Y N G A S ++ V Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV-------- 5350 Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255 + P+ +P S + L +PP++++ +KV+ G S+ Sbjct: 5351 -RGPDEPEEKPASDVHEQL---------------------VPPRMLERFTPKKVKKGSSI 5388 Query: 1256 ELFGKVTGTQPITCTWMKFRKQI------QESEHMKVENSENGSKLTILAARQEHCGCYT 1309 KV G T W++ + ++ V +S L +L ++H G YT Sbjct: 5389 TFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYT 5448 Query: 1310 LLVENKLGSRQAQVNLTVVDKP 1331 + N G +L V P Sbjct: 5449 CIASNAAGQALCSASLHVSGLP 5470 Score = 59.7 bits (143), Expect = 3e-08 Identities = 58/247 (23%), Positives = 88/247 (35%), Gaps = 42/247 (17%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 AP F + + V+ GK L CQ+ +P + W + + + L+Q+G L ++ Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 I D G Y C A+N G+A + + VD A Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAAC----------------------- 105 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 A P + P +VR G +V G+ +W K + Sbjct: 106 -----------------AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGR 148 Query: 1277 QIQESE--HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 ++ E + ++VE S L I AAR G Y + EN LG+ A L V Sbjct: 149 RLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADT 208 Query: 1335 AGTPCAS 1341 A P S Sbjct: 209 ASRPGTS 215 Score = 59.7 bits (143), Expect = 3e-08 Identities = 78/327 (23%), Positives = 132/327 (40%), Gaps = 49/327 (14%) Query: 394 VVSKAANRRIPMEGQRDSAFPK-------FESKPQSQEVKENQTVKFRCEVSGIPKPEVA 446 V+ A + EG SA + F+ K + Q V+E +V E++ P PE+ Sbjct: 1961 VLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTR-PWPELR 2019 Query: 447 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVER 506 W T + + ++E++ + H L L D G + C + + Q T+++ + Sbjct: 2020 WTRNATALAPGK-NVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ--AKLTVEMRQ 2076 Query: 507 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 566 + ++ + + + A +E Q + V G +W +G Q TC V Sbjct: 2077 VRLVRGLQAVEAREQGTATMEVQ--LSHADVDG------SWTRDGLRFQQG-PTCHLAVR 2127 Query: 567 ----ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622 L + PED G AE V SA + V E LPV+ S+P Sbjct: 2128 GPMHTLTLSGLRPEDSGLMVFKAEG----VHTSARLVVTE----------LPVSFSRP-- 2171 Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682 L D+ + +VT+ ++S P +V WL +G E++ + +G SL I Sbjct: 2172 ------LQDVVTTEKEKVTLECELS-RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224 Query: 683 QEVFPEDTGTYTCEAWN--SAGEVRTQ 707 D G Y C+A + S+ V+ Q Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQ 2251 Score = 59.7 bits (143), Expect = 3e-08 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%) Query: 1809 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 I V +D +Y N++G A +A L+V +E E Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357 Score = 58.2 bits (139), Expect = 8e-08 Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Query: 712 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771 + +P P F+++P++ S+G+ +SC I G+P P V W +D + + F + Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAG-ARFRLA 59 Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818 Q+ D++ L + + +GQY +N +GE V L + +A A Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACA 106 Score = 57.0 bits (136), Expect = 2e-07 Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLE 219 P F +L V GQ +C+++ +P Q TW K PL+ S+RV +S Q+L Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248 I V +D+GVYTC V N G + + L Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551 Score = 55.8 bits (133), Expect = 4e-07 Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 9/150 (6%) Query: 1750 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP 1809 N + A +++ + S + S G+ T+ L A E + AE P P Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMR-------AEGAPASPP 240 Query: 1810 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 S R V EG AR C + G P PE VW KD Q + E R + D N L I Sbjct: 241 --STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 D YTC A N +G+ + ++V Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328 Score = 53.9 bits (128), Expect = 1e-06 Identities = 80/295 (27%), Positives = 113/295 (38%), Gaps = 57/295 (19%) Query: 1067 LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPP 1126 LK + D R + R E + F + L D+ E L LQC+VS DP Sbjct: 2616 LKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS-DPE 2674 Query: 1127 ATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV 1185 A ++W +G L + K+ L G+ V + PED GLY C G E +V Sbjct: 2675 AHVVWRKDGVQLGPSDKYDFLHTAGTRGLV-VHDVSPEDAGLYTC----HVGSEETRARV 2729 Query: 1186 TVDDAPASENTKAPEMKSRRPKS-SLPPVLGTESDA------------------------ 1220 V D + M+ +S S VL ES + Sbjct: 2730 RVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQG 2789 Query: 1221 ----TVKKKPAPK-----------TPPKAAM-----PPQIIQFPEDQKVRAGESVELFGK 1260 V ++ AP KA++ P II+ EDQ V GE VEL + Sbjct: 2790 RKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE 2849 Query: 1261 VT--GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313 ++ GT P+ W+K RK I++S+ V + L I A + G YT VE Sbjct: 2850 LSRAGT-PV--HWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901 Score = 53.1 bits (126), Expect = 2e-06 Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 1/113 (0%) Query: 603 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662 +K + + L S AP FL+ LSD V+ G VT+ QVS P + W +G Sbjct: 7443 RKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAP 7502 Query: 663 IQESEDFHFEQRGTQHS-LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714 ++ S L I V ED G YTC N+ G V T VL E Sbjct: 7503 LESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAE 7555 Score = 53.1 bits (126), Expect = 2e-06 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----L 568 AP+F L D V+ GQ L C V P + TW +G P++ + + + L Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521 Query: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 606 I + ED G YTC NALG V+ + + E+ SS Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSS 7559 Score = 52.4 bits (124), Expect = 4e-06 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%) Query: 1799 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1858 A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++ Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159 Query: 1859 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901 +E G S L I D Y +A N LG A+ A L+V++ Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203 Score = 52.0 bits (123), Expect = 6e-06 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + V G A C+I G P P+V W KD Q + F++ D D L Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 I D+ D +Y C+A N++GEA L V+ Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100 Score = 51.6 bits (122), Expect = 7e-06 Identities = 74/357 (20%), Positives = 127/357 (35%), Gaps = 59/357 (16%) Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIIL---SQEGSLCSVSIEKALPEDR 1165 V EGK L C V+ +P +W +G+ + + ++ +QE + + K DR Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ--SDR 306 Query: 1166 GLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV---------- 1213 GLY C A N GQ S V V + P + + E++ + + L V Sbjct: 307 GLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWF 366 Query: 1214 ----------------LGTESDATVKKKPA-------------PKTPPKAAMPPQII-QF 1243 GTE TV+ A +T + A+ ++ + Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKL 426 Query: 1244 PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQE 1303 P VR G++ +F W++ ++++ + + LTI E Sbjct: 427 PRKTAVRVGDTA-MFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485 Query: 1304 HCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSLTLSWYGSSY-DG 1359 G + G Q V PP P +++ SS+ LSW + + Sbjct: 486 DVGQVAFMA----GDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGER 541 Query: 1360 GSAVQSYSIEIWDSANKTW---KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413 + Y +E TW E + V D+ + ++FRV A+N +G S Sbjct: 542 PVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS 598 Score = 51.2 bits (121), Expect = 9e-06 Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106 G TA+FE + G P+P VTW+++ + R L T+SLV+ V +D G YTC Sbjct: 6371 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR-LSQQQEGTTYSLVLRHVASKDAGVYTC 6429 Query: 107 EATNGSGARQVTVELTVEG 125 A N G EL V G Sbjct: 6430 LAQNTGGQVLCKAELLVLG 6448 Score = 50.4 bits (119), Expect = 2e-05 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 P+ + ++DV G + + DP ++ W + L + + QEG+ S+ + Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 6416 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE 1194 +D G+Y C+A+N GQ C ++ V D+ P SE Sbjct: 6417 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSE 6456 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 7/93 (7%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158 F ++L D + EG+ L L C+ S+ D P + WT +GKTL+ + LS EG + I Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGHRAQLLIT 3155 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 A +D G YKC +AG A S V V P Sbjct: 3156 GATLQDSGRYKC----EAGGACSSSIVRVHARP 3184 Score = 49.7 bits (117), Expect = 3e-05 Identities = 73/332 (21%), Positives = 116/332 (34%), Gaps = 24/332 (7%) Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS---GKASMSAE 247 +V W KG +QP R V + Q+L I G +D G Y C + GS A+ Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSICPAAATFQVA 4712 Query: 248 LSIQGLDSANRSFVRETKATNSDVR-----KEVTNVISKESKLDSLEAAAKSKNCSS--P 300 LS +D A + + A D+ +S+E LDS+ + S P Sbjct: 4713 LSPASVDEAPQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDGRSQRLP 4772 Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITL--QAARVQPEPRA 358 Q + E D T+ T S +T +A R P A Sbjct: 4773 QEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLA 4832 Query: 359 PGLGV-LSPSGEERKRPAP---PRPATFPTRQPGLGSQDVVSKAANRRIPMEG------Q 408 +G +PS + +++ P RP LG + A + +G Sbjct: 4833 SKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEM 4892 Query: 409 RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR-RQEGSIEVYEDA 467 + P F E + ++ C V+ W +G + + I+ D Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGD- 4951 Query: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQLSCS 499 G+ L + D+G Y+C SN GQ++ S Sbjct: 4952 GTCSLLITGLDRADAGCYTCQVSNKFGQVTHS 4983 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 16/125 (12%) Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE-G 1150 +S AP F ++L D V G+ + L CQVS+ P A W+ +G L+++ +++S Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516 Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210 + ++I + ED G+Y C +V +A + T K+ RP SS Sbjct: 7517 NFQLLTILVVVAEDLGVYTC---------------SVSNALGTVTTTGVLRKAERPSSSP 7561 Query: 1211 PPVLG 1215 P +G Sbjct: 7562 CPDIG 7566 Score = 49.3 bits (116), Expect = 4e-05 Identities = 40/182 (21%), Positives = 65/182 (35%), Gaps = 26/182 (14%) Query: 366 PSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEV 425 P G E++ P +P R GL S D P F + + V Sbjct: 7433 PEGLEKEGPPRKKPGLASFRLSGLKSWDRA------------------PTFLRELSDETV 7474 Query: 426 KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485 Q+V C+VS P + W +G P+ + L +L D G Y Sbjct: 7475 VLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVY 7534 Query: 486 SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ--------DFVLQCSV 537 +C+ SNA G ++ + L+ P V D ++ + +++QCS+ Sbjct: 7535 TCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSL 7594 Query: 538 RG 539 G Sbjct: 7595 EG 7596 Score = 48.1 bits (113), Expect = 8e-05 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L + Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +V DDDA Y C+ + AEL V+ Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419 Score = 47.8 bits (112), Expect = 1e-04 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%) Query: 1802 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 1854 EEKP V P + +V +GS+ F K+EG P P V W +++ E Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413 Query: 1855 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906 I D G SL++ DV YTC A N+ G+A C+A L V + + E Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473 Query: 1907 GEGEEEE 1913 + + +E Sbjct: 5474 EQEKVKE 5480 Score = 47.8 bits (112), Expect = 1e-04 Identities = 26/87 (29%), Positives = 38/87 (43%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91 AP F+ + + G + +V P Q TW ++G P+ S R L+ ++ L Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521 Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVT 118 I V ED G YTC +N G T Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548 Score = 47.0 bits (110), Expect = 2e-04 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 5/89 (5%) Query: 1099 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158 +F + LQDV E +K+ L+C++S P + W +G L+ K + ++ +G+ S++I Sbjct: 2167 SFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225 Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187 + D+G+Y C DA A+ S V V Sbjct: 2226 RCEFADQGVYVC----DAHDAQSSASVKV 2250 Score = 46.6 bits (109), Expect = 2e-04 Identities = 54/236 (22%), Positives = 86/236 (36%), Gaps = 16/236 (6%) Query: 1020 SGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKR 1079 + PL A A ++KP +P ++P ++L S + K V + Sbjct: 4828 TSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMD------KAAVKIQA 4881 Query: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1139 G ++ + +G P F D G L L+C V+S W +G L Sbjct: 4882 AFKGYKVRKEMKQQEG--PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT 4939 Query: 1140 TTKFIILSQEG-SLCSVSIEKALPEDRGLYKCVAKNDAGQ-AECSCQVTVDDAPASENTK 1197 + + Q G CS+ I D G Y C N GQ +C V +E++ Sbjct: 4940 DGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSS 4999 Query: 1198 APEMKS--RRPKSSLPPVLGTESDATVKKK----PAPKTPPKAAMPPQIIQFPEDQ 1247 E+ RR L + T+S A V + A + P + P + ED+ Sbjct: 5000 GGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDE 5055 Score = 46.6 bits (109), Expect = 2e-04 Identities = 53/231 (22%), Positives = 87/231 (37%), Gaps = 46/231 (19%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1156 P F+++L D G+ + L C+V+ P I W +GK ++ I++ C++ Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 ++ D G Y C A + AG ++ V P N K R + P V G Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVN------KVR----ASPFVEGE 6123 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 ++ T + AP PQI + + + G KF+ Sbjct: 6124 DAQFTCTIEGAPY--------PQIRWYKDGALLTTGN-------------------KFQT 6156 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 + + V L I AA +E G Y + N+LGS +A L + Sbjct: 6157 LSEPRSGLLV--------LVIRAASKEDLGLYECELVNRLGSARASAELRI 6199 Score = 44.3 bits (103), Expect = 0.001 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F++ L+D+ V EG L+C +SS A + W L+ L QEG++ + + Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSS-VAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRN 3245 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 P+D G Y C G S +TV PA Sbjct: 3246 LRPQDSGRYSC----SFGDQTTSATLTVTALPA 3274 Score = 44.3 bits (103), Expect = 0.001 Identities = 63/266 (23%), Positives = 98/266 (36%), Gaps = 24/266 (9%) Query: 433 FRCEVS-GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG--TYSCTA 489 F C +S +P E +W++ G V+ + V D H L L A+ +G T++C Sbjct: 4451 FTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRD 4510 Query: 490 SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549 + A +L+ A + S + L A + L C R + Sbjct: 4511 AVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGL-CGYR-------VEVK 4562 Query: 550 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609 G Q+ E + P + + A +G A VH ++ R + Sbjct: 4563 EGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVG-----AGEPVHLPQTVRLA 4617 Query: 610 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669 E PV P +P+AP +V G V++ ++V EVIW IQ F Sbjct: 4618 EPPKPVPP-QPSAP------ESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRF 4669 Query: 670 HFEQRGTQHSLCIQEVFPEDTGTYTC 695 +G Q L I+ ED G Y C Sbjct: 4670 EVVSQGRQQMLVIKGFTAEDQGEYHC 4695 Score = 43.5 bits (101), Expect = 0.002 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208 V P + PP A + V+ + + + +++ + VTWLK L P + Sbjct: 697 VRAAPGLTANKPPAAAAR--EVLARLHEEAQLLAELSDQAAA-VTWLKDGRTLSPGPKYE 753 Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253 V G +VL + V +DD G+Y C+ G ++ +LS+QGL Sbjct: 754 VQASAGRRVLLVRDVARDDAGLYECVSRGG----RIAYQLSVQGL 794 Score = 43.5 bits (101), Expect = 0.002 Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 5/138 (3%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGS-LCSV 1155 P F K++ EG+ C + P I W +G L T KF LS+ S L + Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167 Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV 1213 I A ED GLY+C N G A S ++ + A E ++ + ++L Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERA 6227 Query: 1214 LGTESDATVKKKPAPKTP 1231 E + +K+ PK P Sbjct: 6228 -DQEVTSVLKRLLGPKAP 6244 Score = 43.5 bits (101), Expect = 0.002 Identities = 26/89 (29%), Positives = 35/89 (39%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + + D VV G + C++ P + W KD + S I L Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897 I V +D YTC N+LG T T L Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551 Score = 42.7 bits (99), Expect = 0.003 Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%) Query: 1745 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1804 W K G +R R G + TG+ K E+ S + + Sbjct: 3128 WTKDGKTLRGSARCQLSH--EGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRV----- 3180 Query: 1805 PHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 H +P F + ++DLEV+EG AA C + P V W + +R + + E Sbjct: 3181 -HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGA 3237 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902 L++ ++ D +Y+C S G+ T +A L V + Sbjct: 3238 MLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272 Score = 42.4 bits (98), Expect = 0.004 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F KL++ EG L+C++S P + W +TL+ L Q+G++C + I Sbjct: 3276 FIGKLRNKEATEGATATLRCELSKAAP--VEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 D Y CV G+ S +T+ PA Sbjct: 3334 LAMVDAAEYSCV----CGEERTSASLTIRPMPA 3362 Score = 42.4 bits (98), Expect = 0.004 Identities = 39/155 (25%), Positives = 62/155 (40%), Gaps = 17/155 (10%) Query: 1049 PMGNAKPDENLKSASKEELKKD-------VKNDVNCKRGHAGTTDNEKRSESQGTAPA-- 1099 P+ K E+L+ + L++D + G E+R+ + T A Sbjct: 3390 PVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALP 3449 Query: 1100 --FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 F + L++ EG +L C++S P + W + L+ IL QEG+ C + I Sbjct: 3450 AKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRDGDRYILRQEGTRCELQI 3507 Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 D G Y CV GQ S +T+ PA Sbjct: 3508 CGLAMADAGEYLCV----CGQERTSATLTIRALPA 3538 Score = 41.2 bits (95), Expect = 0.010 Identities = 44/204 (21%), Positives = 71/204 (34%), Gaps = 40/204 (19%) Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104 +EG A F+ V + V W R+G + +F + + SL I + ED G+ Sbjct: 1911 EEGGEATFQCVVSP-SDVAVVWFRDGALLQPSEKFAISQS-GASHSLTISDLVLEDAGQI 1968 Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164 T EA S + + V E P F Sbjct: 1969 TVEAEGASSSAALRVR-------------------------------------EAPVLFK 1991 Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224 KL V+E ++T RP P++ W + L P V + + L +H V Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050 Query: 225 QDDVGVYTCLVVNGSGKASMSAEL 248 D G + C + +A ++ E+ Sbjct: 2051 FADRGFFGCETPDDKTQAKLTVEM 2074 Score = 40.4 bits (93), Expect = 0.017 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 P +F L + V EG C ++ P V W GN L+P + S+ ++ M L Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267 + + D G Y+C G + SA L++ L + +R +AT Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTALPAQFIGKLRNKEAT 3286 Score = 38.9 bits (89), Expect = 0.049 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 5/78 (6%) Query: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1170 E + ++L C P A + W + L ++ +S EG + + I + +P D G+Y+C Sbjct: 2482 ELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC 2540 Query: 1171 VAKNDAGQAECSCQVTVD 1188 AG A S +VTV+ Sbjct: 2541 ----QAGSAHSSTEVTVE 2554 Score = 37.4 bits (85), Expect = 0.14 Identities = 46/236 (19%), Positives = 84/236 (35%), Gaps = 49/236 (20%) Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133 + +C+ G + + +E +G + +V G +L C+V+ P + W Sbjct: 1143 EYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQ-PQTEVTWYK 1201 Query: 1134 NGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS 1193 +GK L ++ + + +G + +++ D G Y C +AG S Q+ + Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSC----EAGGQRVSFQLHI------ 1251 Query: 1194 ENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGE 1253 T PKA + + E + AG Sbjct: 1252 ------------------------------------TEPKAVFAKEQLVHNE-VRTEAGA 1274 Query: 1254 SVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309 S L +V Q TW K K++ S +++E + +L + A Q G YT Sbjct: 1275 SATLSCEVAQAQ-TEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYT 1329 Score = 37.4 bits (85), Expect = 0.14 Identities = 56/248 (22%), Positives = 89/248 (35%), Gaps = 47/248 (18%) Query: 20 DPSRVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78 D + ++ +T PA FI RN EGATA R V W + + + G R Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATL--RCELSKAAPVEWRKGSETLRDGDR 3317 Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138 + L L I + D +Y+C G + + LT+ Sbjct: 3318 YCLRQD-GAMCELQIRGLAMVDAAEYSCVC----GEERTSASLTI--------------- 3357 Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198 RP P F +L EG C+++ V W KG Sbjct: 3358 -------------RPM-----PAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRKGR 3397 Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258 L+ R S+ + + L+I G+ D G Y+C+ G+ SA L+++ L + Sbjct: 3398 ESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCV----CGEERTSATLTVKALPAKFT 3453 Query: 259 SFVRETKA 266 +R +A Sbjct: 3454 EGLRNEEA 3461 Score = 37.4 bits (85), Expect = 0.14 Identities = 37/137 (27%), Positives = 55/137 (40%), Gaps = 21/137 (15%) Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354 K S+PQ G SP A P PP SCK++P P +P L + + Sbjct: 7038 KQGSAPQEGCSPHPAV--APCPPGSFPPGSCKEAP-LVPSSPFLGQPQA----------- 7083 Query: 355 EPRAPGLGVLSPSGEERKRPA----PPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410 P AP SP + + P P RP P PG SQ S+ ++ R+ Sbjct: 7084 -PPAPAKA--SPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGT 7140 Query: 411 SAFPKFESKPQSQEVKE 427 P +++ +QE ++ Sbjct: 7141 EPGPSLDAEGWTQEAED 7157 Score = 37.0 bits (84), Expect = 0.19 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%) Query: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867 +P F + ++ L+ EGS A C++ P VVW K ++ + + + L Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946 Query: 1868 IISDVCGDDDAKYTCKAVNSLGEATCT 1894 ++ D+ +D +YTC + AT T Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973 Score = 36.6 bits (83), Expect = 0.24 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 + +RD +E +C++ +V WFK Q ++ +++ D LIISDV Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAELIVE 1900 +D+ YTC A G+ +A+ VE Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375 Score = 36.6 bits (83), Expect = 0.24 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F +L+ EG L+C++S P + W ++L+ L Q+G++C + I Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRDGDRHSLRQDGAVCELQICG 3421 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 D G Y CV G+ S +TV PA Sbjct: 3422 LAVADAGEYSCV----CGEERTSATLTVKALPA 3450 Score = 36.6 bits (83), Expect = 0.24 Identities = 23/80 (28%), Positives = 36/80 (45%) Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106 G + E V + + W ++G +T G +D GT SL+I + D G YTC Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971 Query: 107 EATNGSGARQVTVELTVEGS 126 + +N G + + V GS Sbjct: 4972 QVSNKFGQVTHSACVVVSGS 4991 Score = 35.8 bits (81), Expect = 0.41 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 F L V EG + QC VS A ++W +G L+ ++ +SQ G+ S++I Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISD 1959 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 + ED G A+ A S + V +AP Sbjct: 1960 LVLEDAGQITVEAEG----ASSSAALRVREAP 1987 Score = 35.4 bits (80), Expect = 0.54 Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 1246 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEH 1304 D + + G+++ L V + W+K ++ + H ++ +G+ L I + Sbjct: 4906 DTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRAD 4965 Query: 1305 CGCYTLLVENKLG 1317 GCYT V NK G Sbjct: 4966 AGCYTCQVSNKFG 4978 Score = 35.4 bits (80), Expect = 0.54 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 20/125 (16%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF--EVLQNEDVFT 778 P F+ + T LGQSV ++C ++ P W +DG L + L+N + T Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522 Query: 779 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN-SSARALPRGREPAS--CEDLCGGG 835 ++ +++ +G +C VS L ++ L + P+S C D+ G Sbjct: 7523 IL-------------VVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDI--GE 7567 Query: 836 VGADG 840 V ADG Sbjct: 7568 VYADG 7572 Score = 35.0 bits (79), Expect = 0.70 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%) Query: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846 ES +D + A L P V + S + + EG A F C + D VVWF+D Sbjct: 1881 ESRDDHTSAQLTVSV---PRVVKFMSG-LSTVVAEEGGEATFQCVVSP-SDVAVVWFRDG 1935 Query: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1891 ++ S F I + SL ISD+ +D + T +A + A Sbjct: 1936 ALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSA 1979 Score = 35.0 bits (79), Expect = 0.70 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159 FK+KL+ V E + L+ +++ P + WT N L K + + EG+ + + Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELTRPWPE-LRWTRNATALAPGKNVEIHAEGARHRLVLHN 2048 Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQV 1185 DRG + C +D QA+ + ++ Sbjct: 2049 VGFADRGFFGCETPDDKTQAKLTVEM 2074 Score = 35.0 bits (79), Expect = 0.70 Identities = 22/100 (22%), Positives = 39/100 (39%) Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294 A PP + ED + + G + + + G + TW K Q+ +S + + Sbjct: 6354 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 6413 Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334 L + + G YT L +N G + L V+ + P Sbjct: 6414 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP 6453 Score = 34.3 bits (77), Expect = 1.2 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%) Query: 1810 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1869 +F +R E +EG+ A C++ E W K +S+R+ + D C L I Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419 Query: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914 + D +Y+C GE +A L V+ + EG EE Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460 Score = 34.3 bits (77), Expect = 1.2 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%) Query: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 1857 A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++ Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388 Query: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 + E+G L++ D +C+ G+ +A L V Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427 Score = 34.3 bits (77), Expect = 1.2 Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 12/106 (11%) Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-------KTTKFIILS--Q 1148 P ++ V +G + +V P T+ W T + + S Q Sbjct: 5371 PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQ 5430 Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194 + SL + + + + +G Y C+A N AGQA CS + V P E Sbjct: 5431 QHSLVLLDVGR---QHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473 Score = 33.9 bits (76), Expect = 1.6 Identities = 20/98 (20%), Positives = 39/98 (39%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F A +G ++ + C +A WL+DG L H + +L+ Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818 + + AG Y + N+ G+ + +++ S + A Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEA 4995 Score = 33.1 bits (74), Expect = 2.7 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 A F + L+ V G + L C++S A ++W L+ K + EG + S++ Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLT 1866 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQV 1185 + ED G Y C +++D A+ + V Sbjct: 1867 VLGLRAEDAGEYVCESRDDHTSAQLTVSV 1895 Score = 32.7 bits (73), Expect = 3.5 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 1817 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 1874 +++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230 Query: 1875 DDDAKYTCKA 1884 D +Y+C+A Sbjct: 1231 ADAGEYSCEA 1240 Score = 32.7 bits (73), Expect = 3.5 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112 +V WH+ + I GGRF + R LVI ED+G+Y C GS Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQM-LVIKGFTAEDQGEYHCGLAQGS 4701 Score = 32.7 bits (73), Expect = 3.5 Identities = 20/62 (32%), Positives = 28/62 (45%) Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296 PP + D GE+V+L +VTGT +W K K +Q H + +GS Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072 Query: 1297 IL 1298 IL Sbjct: 6073 IL 6074 Score = 32.3 bits (72), Expect = 4.6 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 1813 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1872 K + D V G C++ P V W KD ++IR+S+ + + E L+I Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888 Query: 1873 CGDDDAKYTCKAVNSLGEATCTAE 1896 D +YTC+ S A+ E Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912 Score = 32.3 bits (72), Expect = 4.6 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1870 F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508 Query: 1871 DVCGDDDAKYTCKAVNSLGEATCT 1894 + D +Y C AT T Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532 Score = 32.0 bits (71), Expect = 6.0 Identities = 45/163 (27%), Positives = 61/163 (37%), Gaps = 25/163 (15%) Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 V WL +G + + + + L +++V +D G Y C + G + Q L+VQ Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAYQ--LSVQ 792 Query: 714 EPHDGTQPWFISKPRS---VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF-E 769 F+ K + V A G C + VHW +DG L GH E Sbjct: 793 -----GLARFLHKDMAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMEL----GHSGE 842 Query: 770 VLQNEDVFT---LVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 EDV T LV V G Y RVGE S L Sbjct: 843 RFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRL 881 Score = 32.0 bits (71), Expect = 6.0 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 + D++V EGS+A F C+I V WF D + + +ID G L + + Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070 Query: 1875 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 1906 D +A + A + EL T+ EGE Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111 >gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo sapiens] Length = 473 Score = 202 bits (514), Expect = 3e-51 Identities = 113/324 (34%), Positives = 180/324 (55%), Gaps = 5/324 (1%) Query: 1460 VSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHP 1519 +SDF+++E LG G V+R +K T+K +A K K +K+ +R EI ++ L HP Sbjct: 42 LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK--KTVDKKIVRTEIGVLLRLSHP 99 Query: 1520 KLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQ 1579 +++ + FE I +VLE+V+GGELF+RI+++ + +ER+ ++QI E V Y+H+ Sbjct: 100 NIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY-YSERDAADAVKQILEAVAYLHEN 158 Query: 1580 GIVHLDLKPENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI 1638 GIVH DLKPEN++ +K+ DFGL++ +E+ +K + GTP + APE++ Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218 Query: 1639 GYATDMWSIGVICYILVSGLSPFMGD-NDNETLANVTSATWDFDDEAFDEISDDAKDFIS 1697 G DMWS+G+I YIL+ G PF + D + + + F +DE+S +AKD + Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278 Query: 1698 NLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGR 1757 L+ D K RL Q LQHPW+ N ++ +++++ ARRK + AV A R Sbjct: 279 KLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 338 Query: 1758 LSSMAMISGLSGRKSSTGSPTSPL 1781 L S + G SP+ Sbjct: 339 LGSASSSHGSIQESHKASRDPSPI 362 >gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM kinase isoform b [Homo sapiens] Length = 360 Score = 202 bits (513), Expect = 3e-51 Identities = 110/325 (33%), Positives = 186/325 (57%), Gaps = 6/325 (1%) Query: 1443 KEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE 1502 + P D + +TE +S Y+I ERLGSG F +V E+ + + A K + + Sbjct: 12 RRPSGDMLLLKKHTED-ISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRG 70 Query: 1503 KEN-IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERE 1561 KE + EI+++ + HP +V D E +++ + +E+V+GGELF+RI++ TE++ Sbjct: 71 KEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERG-SYTEKD 129 Query: 1562 CIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNK-TGTRIKLIDFGLARRLENAGSLKV 1620 + Q+ V Y+H GIVH DLKPEN++ ++I + DFGL++ ++ L Sbjct: 130 ASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSK-IQAGNMLGT 188 Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680 GTP +VAPE++ +P G A D+W++GVI YIL+ G PF ++D E + + A+++F Sbjct: 189 ACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEF 248 Query: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKY 1739 D +D+IS+ AKDFI +LL++D + R C Q L+H W+ DT + + ++++K Sbjct: 249 DSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKN 308 Query: 1740 MARRKWQKTGNAVRAIGRLSSMAMI 1764 AR W++ NA + + + I Sbjct: 309 FARTHWKRAFNATSFLRHIRKLGQI 333 >gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM kinase isoform a [Homo sapiens] Length = 426 Score = 201 bits (510), Expect = 7e-51 Identities = 106/310 (34%), Positives = 180/310 (58%), Gaps = 5/310 (1%) Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516 + +S Y+I ERLGSG F +V E+ + + A K + + KE + EI+++ + Sbjct: 92 EDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRI 151 Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576 HP +V D E +++ + +E+V+GGELF+RI++ TE++ + Q+ V Y+ Sbjct: 152 SHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERG-SYTEKDASHLVGQVLGAVSYL 210 Query: 1577 HKQGIVHLDLKPENIMCVNK-TGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635 H GIVH DLKPEN++ ++I + DFGL++ ++ L GTP +VAPE++ Sbjct: 211 HSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSK-IQAGNMLGTACGTPGYVAPELLEQ 269 Query: 1636 EPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDF 1695 +P G A D+W++GVI YIL+ G PF ++D E + + A+++FD +D+IS+ AKDF Sbjct: 270 KPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDF 329 Query: 1696 ISNLLKKDMKNRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1754 I +LL++D + R C Q L+H W+ DT + + ++++K AR W++ NA Sbjct: 330 IRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRAFNATSF 389 Query: 1755 IGRLSSMAMI 1764 + + + I Sbjct: 390 LRHIRKLGQI 399 >gi|157785645 SPEG complex locus [Homo sapiens] Length = 3267 Score = 200 bits (508), Expect = 1e-50 Identities = 113/357 (31%), Positives = 198/357 (55%), Gaps = 9/357 (2%) Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1517 +++SDFYDI + +G G F + R+VE+ + +A KF + AK K + R+E ++ L Sbjct: 1595 RRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPS-QAKPKASARREARLLARLQ 1653 Query: 1518 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1577 H ++ +AFE + +V+V E+ + EL ERI + + E E YMRQ+ EG+ Y+H Sbjct: 1654 HDCVLYFHEAFERRRGLVIVTELCTE-ELLERIARKP-TVCESEIRAYMRQVLEGIHYLH 1711 Query: 1578 KQGIVHLDLKPENIMCVNKTG--TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635 + ++HLD+KPEN++ + ++++ DFG A+ L +GTPEFVAPE++N Sbjct: 1712 QSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQ 1771 Query: 1636 EPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDF 1695 P+ TD+W +GV+ ++ ++G+SPF+G+ND TL N+ + F++ F +S +A+ F Sbjct: 1772 SPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGF 1831 Query: 1696 ISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAI 1755 + +L +D + R + L+HPW K E +S D +K +++RR+WQ++ + + Sbjct: 1832 LIKVLVQD-RLRPTAEETLEHPWFKTQAKGAE---VSTDHLKLFLSRRRWQRSQISYKCH 1887 Query: 1756 GRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFS 1812 L + + + P P + L S D + LE + ++P FS Sbjct: 1888 LVLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFS 1944 Score = 186 bits (471), Expect = 2e-46 Identities = 141/480 (29%), Positives = 206/480 (42%), Gaps = 69/480 (14%) Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423 LSP EE P P T PT +P S + NRR G + A P F+ Q Sbjct: 831 LSPP-EEFPEPGETWPRT-PTMKP--------SPSQNRRSSDTGSK--APPTFKVSLMDQ 878 Query: 424 EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483 V+E Q V V G PKP V+W PVR + + G L +L A D+G Sbjct: 879 SVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAG 938 Query: 484 TYSCTASNAQGQLSCSWTLQV----ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539 Y+C A N G C L+V E ++ +AP L+D V G+ + +C V G Sbjct: 939 FYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAP-----LQDVDVGAGEMALFECLVAG 993 Query: 540 TPVPRITWLLNGQPIQYARSTC----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595 + WL G+ +Q A C + +L + +D G YTC A +++CS Sbjct: 994 PTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCS 1053 Query: 596 AWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI 655 A +TV PS AP+F + L D++V++G ++SG PPP V Sbjct: 1054 ARLTVR---------------PS--LAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVT 1096 Query: 656 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715 W H G ++ESE+ Q G HSL I V ED G Y A N+ G+ A L V+EP Sbjct: 1097 WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEP 1156 Query: 716 HDGTQ--------------------------PWFISKPRSVTASLGQSVLISCAIAGDPF 749 P F+ + + L + ++ C + G P+ Sbjct: 1157 RTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPY 1216 Query: 750 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809 PT+ W +G + + + + Q DV LV V P HAG Y+ ++ N++G+ +C L Sbjct: 1217 PTISWFHNGHRI-QSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL 1275 Score = 167 bits (422), Expect = 1e-40 Identities = 167/632 (26%), Positives = 245/632 (38%), Gaps = 82/632 (12%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220 P F L VVV G C IT P PQV+W K L+ R+ + + L + Sbjct: 722 PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLL 781 Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280 D G Y N G+A+ +A L+++ + S +T S Sbjct: 782 REARAADAGSYMATATNELGQATCAASLTVR------------PGGSTSPFSSPIT---S 826 Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340 E L E P+ G + P +P P + + D+ AP T + Sbjct: 827 DEEYLSPPE--------EFPEPGETWPRTPTMKPSPSQNRR---SSDTGSKAPPTFKVSL 875 Query: 341 TSSSI-----TLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG------- 388 S+ + + RVQ EP+ P + L ++P P F G Sbjct: 876 MDQSVREGQDVIMSIRVQGEPK-PVVSWL-----RNRQPVRPDQRRFAEEAEGGLCRLRI 929 Query: 389 LGSQD-----VVSKAANR--------RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC 435 L ++ KA N R+ + +S + Q +V + F C Sbjct: 930 LAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFEC 989 Query: 436 EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495 V+G EV W G ++ +++ D L L DSG Y+C S A+ + Sbjct: 990 LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDE 1049 Query: 496 LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 555 L+CS L V +AP F+ +L+D V+EG+ C + GTP P +TW G P++ Sbjct: 1050 LTCSARLTVRP----SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPME 1105 Query: 556 YA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-----SR 607 + R + G+ LHI ED G Y A N GQ CSA + V E ++ S Sbjct: 1106 ESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSS 1165 Query: 608 KSEYLLPVAPSKP--------TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659 K E + P P +P + P FL+ L DL+V + + QV+G P P + W HN Sbjct: 1166 KLEKM-PSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHN 1224 Query: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE----P 715 G+ IQ S+D Q H L V P+ G Y N G+ A L V + P Sbjct: 1225 GHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGP 1284 Query: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747 DG R VT + + AI D Sbjct: 1285 PDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPD 1316 Score = 146 bits (369), Expect = 2e-34 Identities = 102/348 (29%), Positives = 172/348 (49%), Gaps = 19/348 (5%) Query: 1415 PSQESELTTVGEKPEEPKDEVEVS--DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGS 1472 P E T V + P EV S P + T+ QK F + + R Sbjct: 2918 PEPPPEPTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKAR--- 2974 Query: 1473 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1532 G+FG V E T + + K Y+A+ K + QE ++ LHH +++ +A+ Sbjct: 2975 GRFGVVRACRENATGRTFVAKIVP-YAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPR 3033 Query: 1533 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1592 +V++ E EL + D F +E + YM Q+ +G++Y+H ++HLD+KP+N++ Sbjct: 3034 YLVLIAESCGNRELLCGLSDR-FRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLL 3092 Query: 1593 CVNKTGTRIKLIDFGLARRLENAGSLKVL---FGTPEFVAPEVINYEPIGYATDMWSIGV 1649 +K++DFG A+ N +L+ L GT EF+APE++ EPIG ATD+W GV Sbjct: 3093 LAPDNA--LKIVDFGSAQPY-NPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGV 3149 Query: 1650 ICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLD 1709 + YI++SG SPF + ET A + +D + + S A F+ +L +R Sbjct: 3150 LTYIMLSGRSPFYEPDPQETEARIVGGRFD-AFQLYPNTSQSATLFLRKVLSVHPWSRPS 3208 Query: 1710 CTQCLQHPWLMKDTKNMEAKK----LSKDRMKKYMARRKWQKTGNAVR 1753 CL HPWL +D M+ ++ + +R+K+++ ++ ++ A R Sbjct: 3209 LQDCLAHPWL-QDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATR 3255 Score = 146 bits (368), Expect = 2e-34 Identities = 153/593 (25%), Positives = 229/593 (38%), Gaps = 106/593 (17%) Query: 295 KNCSSPQRGGSPPWAAN---SQPQPPRESKLESCKDSPRTAP-QTPVLQKTSSSITLQAA 350 + C SP PP AA+ ++ + P K E + R P TP L+ + TL+ Sbjct: 605 QECRSPV----PPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKN 660 Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQDVVSKAANRRIPMEGQR 409 R PE E+R R P + P + G SQ +A +E Sbjct: 661 RAGPE------------AEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSD 708 Query: 410 DSAF---------PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460 DS P FE Q+ V V +C ++ P P+V+W +G+ +R EG Sbjct: 709 DSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALR-SEGR 767 Query: 461 IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE--------------- 505 + + + H L L +AR D+G+Y TA+N GQ +C+ +L V Sbjct: 768 LLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSD 827 Query: 506 ------------------RLAVMEVAPS---------------FSSVLKDCAVIEGQDFV 532 R M+ +PS F L D +V EGQD + Sbjct: 828 EEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVI 887 Query: 533 LQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENA 588 + V+G P P ++WL N QP++ + E G+ L I A D G YTC A N Sbjct: 888 MSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNE 947 Query: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 G C A + V SR L P L D+ V G V+G Sbjct: 948 YGARQCEARLEVRAHPESRSLAVLAP--------------LQDVDVGAGEMALFECLVAG 993 Query: 649 NPPPEVIWLHNGNEIQESE---DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705 EV WL G +Q + HF+ G + L + V +D+G YTC+ + E+ Sbjct: 994 PTDVEVDWLCRGRLLQPALLKCKMHFD--GRKCKLLLTSVHEDDSGVYTCKLSTAKDELT 1051 Query: 706 TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765 A LTV+ P F V G++ C I+G P P V W G + +++ Sbjct: 1052 CSARLTVR---PSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPM-EES 1107 Query: 766 GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818 + + Q+ + +L + V G Y + N G+ C L ++ A Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAA 1160 Score = 124 bits (312), Expect = 7e-28 Identities = 177/805 (21%), Positives = 286/805 (35%), Gaps = 119/805 (14%) Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92 P F + + ++EG RV+G P+P V+W RN QP+ R + G L Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928 Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152 I A D G YTC+A N GARQ L V S++L Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAH--------PESRSLA----------- 969 Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212 L V V G+M F C + G +V WL LQP+ Sbjct: 970 ----------VLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHF 1019 Query: 213 NGMQV-LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271 +G + L + V++DD GVYTC + + + SA L+++ S F R + Sbjct: 1020 DGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVR--PSLAPLFTRLLE------ 1071 Query: 272 RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKD 327 ++ LE A +C G+PP W P E+ Sbjct: 1072 ------------DVEVLEGRAARFDCKI---SGTPPPVVTWTHFGCPMEESENLR----- 1111 Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAP-GLGVLSPSGE---------ERKRPAPP 377 L++ +L A V E + ++ G+ E R A Sbjct: 1112 ----------LRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAAS 1161 Query: 378 RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS-AFPKFESKPQSQEVKENQTVKFRCE 436 P++ + P + + P +G+ + + P F Q EV + C+ Sbjct: 1162 GPSSKLEKMPSIPEE-----------PEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQ 1210 Query: 437 VSGIPKPEVAWFLEGTPVRRQEGS-IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495 V+G+P P ++WF G ++ + + Y D H L + +G Y +N G+ Sbjct: 1211 VTGLPYPTISWFHNGHRIQSSDDRRMTQYRDV--HRLVFPAVGPQHAGVYKSVIANKLGK 1268 Query: 496 LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 555 +C L V +V P + G+ L + P + ++ + Sbjct: 1269 AAC-----YAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWN----PPRSLDMAIDPDSLT 1319 Query: 556 YARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE--YL 612 Y G + + L E T L + + K S SE L Sbjct: 1320 YTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQL 1379 Query: 613 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672 L P+ AP L + V++G ++TV + + +V+W + E+ +E Sbjct: 1380 LEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYE 1438 Query: 673 QR---GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729 Q+ L I V D G TC A N G L + E P F S Sbjct: 1439 LSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-----PRFESIMED 1493 Query: 730 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789 V G++ + + G P P + W +D + L ++ H + E+ +LV+ Sbjct: 1494 VEVGAGETARFAVVVEGKPLPDIMWYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQDG 1552 Query: 790 GQYEILLKNRVGECSCQVSLMLQNS 814 G Y +N GE SC+ L + ++ Sbjct: 1553 GVYTCTAQNLAGEVSCKAELAVHSA 1577 Score = 120 bits (301), Expect = 1e-26 Identities = 141/591 (23%), Positives = 211/591 (35%), Gaps = 81/591 (13%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91 AP F ++ + EG A+F+ ++ G P P VTW G P+ L G SL Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GGLHSL 1121 Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151 I V ED G Y A N G + +L VE G S L S P Sbjct: 1122 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP---SSKLEKMPSIPEEPE 1178 Query: 152 RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211 + + P F L + V + C++TG P P ++W +Q S +++ Sbjct: 1179 QGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQ 1238 Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271 + L V GVY ++ N GKA+ A L +V + D Sbjct: 1239 YRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL-----------YVTDVVPGPPDG 1287 Query: 272 RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRT 331 +V V + L W PPR + DS Sbjct: 1288 APQVVAVTGRMVTLT---------------------W------NPPRSLDMAIDPDSLTY 1320 Query: 332 APQTPVLQKTSSSITLQAARVQPEPRAPGLG--------VLSPSGEERKRPAPPRPATFP 383 Q VL + + R +P A GL VLS + + +P+PP Sbjct: 1321 TVQHQVLGSDQWTALVTGLR-EPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPP------ 1373 Query: 384 TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKP 443 S+ V ++ G P KP V E Q + + Sbjct: 1374 -------SEPV-------QLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQ 1419 Query: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHY-LCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502 V G + + G E+ + Y L + + RD G +CTA N G +CS TL Sbjct: 1420 VVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTL 1479 Query: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARS 559 ++ AP F S+++D V G+ V G P+P I W + + + Sbjct: 1480 ELAE------APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSF 1533 Query: 560 TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610 E L + +D G YTC A+N G+VSC A + VH +++ + E Sbjct: 1534 VYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVE 1584 Score = 117 bits (293), Expect = 1e-25 Identities = 91/331 (27%), Positives = 147/331 (44%), Gaps = 25/331 (7%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 AP F + L+DV V EG+ C++S PP + WT G ++ ++ + L Q+G L S+ Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLH 1122 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 I ED GLY A N GQA CS Q+ V++ P + P S L Sbjct: 1123 IAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE---------PRTAASGPSSKL------ 1167 Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276 E ++ ++P + ++ P ++ +D +V + L +VTG T +W Sbjct: 1168 EKMPSIPEEPEQGELERLSI-PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGH 1226 Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD-KPDPPA 1335 +IQ S+ ++ + +L A +H G Y ++ NKLG +L V D P PP Sbjct: 1227 RIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPD 1286 Query: 1336 GTPCASDIRSSSLTLSW-----YGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSF 1389 G P + +TL+W + D S +Y+++ + W L T R + Sbjct: 1287 GAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSL--TYTVQHQVLGSDQWTALVTGLREPGW 1344 Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 L ++ FRV + V +S+PS SE Sbjct: 1345 AATGLRKGVQHIFRVLSTTVKSSSKPSPPSE 1375 Score = 111 bits (277), Expect = 8e-24 Identities = 110/463 (23%), Positives = 180/463 (38%), Gaps = 52/463 (11%) Query: 916 KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPK 975 +E+ RA LQR P+ E R+V +P + P + Sbjct: 508 EELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDE 567 Query: 976 PATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETL 1035 P P R G + P E + + S+ + + P P + A T Sbjct: 568 PGRPRSRGPAGRTE--PGEGPQQEVRRRDQFPLTRSRAIQECRSPVP-PPAADPPEARTK 624 Query: 1036 KPMGNAK--PAETLKPM--------GNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTT 1085 P G + PA+ ++ + G A P K+ + E +K ++ + G G Sbjct: 625 APPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPE-EDGPWGPW 683 Query: 1086 DNE-KRSESQGT-------------------------APAFKQKLQDVHVAEGKKLLLQC 1119 D RS+ +G AP F+ LQ+V VA G +LL+C Sbjct: 684 DRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743 Query: 1120 QVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1179 ++++PP + W +G L++ ++L EG ++ + +A D G Y A N+ GQA Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQA 803 Query: 1180 ECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPK------ 1233 C+ +TV ++ +P S PP E T + P K P Sbjct: 804 TCAASLTVRPGGSTSPFSSPITSDEEYLS--PPEEFPEPGETWPRTPTMKPSPSQNRRSS 861 Query: 1234 ---AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290 + PP DQ VR G+ V + +V G +W++ R+ ++ + E +E Sbjct: 862 DTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAE 921 Query: 1291 NG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332 G +L ILAA + G YT N+ G+RQ + L V P+ Sbjct: 922 GGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964 Score = 107 bits (266), Expect = 1e-22 Identities = 95/352 (26%), Positives = 140/352 (39%), Gaps = 47/352 (13%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH--- 569 AP F L++ V G D +L+C + P P+++W +G ++ E H Sbjct: 721 APVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLL 780 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS--------SRKSEYLLP------- 614 +++A D G+Y A N LGQ +C+A +TV S + EYL P Sbjct: 781 LREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEP 840 Query: 615 --VAPSKPT------------------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654 P PT P F L D V +G V M+++V G P P V Sbjct: 841 GETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVV 900 Query: 655 IWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713 WL N ++ + F E G L I D G YTC+A N G + +A L V+ Sbjct: 901 SWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVR 960 Query: 714 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK----ALCKDTGHFE 769 + ++ + V G+ L C +AG V WL G+ AL K HF+ Sbjct: 961 AHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFD 1020 Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821 + + L+L V +G Y L E +C L ++ S A R Sbjct: 1021 GRKCK----LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTR 1068 Score = 99.8 bits (247), Expect = 2e-20 Identities = 74/244 (30%), Positives = 103/244 (42%), Gaps = 26/244 (10%) Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTF 89 EAP F +P +N+ + GA + + P PQV+WH++G + S GR LL G R T Sbjct: 720 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHT- 778 Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSK----TLGDRF 144 L++ D G Y ATN G LTV G P+ S + + F Sbjct: 779 -LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEF 837 Query: 145 SAPAVETRP----------------SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 P ET P + PP F L V+EGQ S ++ G P Sbjct: 838 PEPG-ETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEP 896 Query: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247 +P V+WL+ P++P R E + G+ L I + D G YTC VN G A Sbjct: 897 KPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEAR 956 Query: 248 LSIQ 251 L ++ Sbjct: 957 LEVR 960 Score = 86.7 bits (213), Expect = 2e-16 Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 38/231 (16%) Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83 V + P + + A + P +++ + G A FE V G + +V W G+ + LL C Sbjct: 959 VRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA---LLKC 1015 Query: 84 GIR---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140 + L++ +VHE+D G YTC+ + + LTV Sbjct: 1016 KMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV----------------- 1058 Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200 RPS+ P F L V V EG+ RF CKI+G P P VTW P Sbjct: 1059 -----------RPSL----APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCP 1103 Query: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 ++ S + + + G+ L I V +D G+Y VN G+A SA+L ++ Sbjct: 1104 MEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154 Score = 85.1 bits (209), Expect = 6e-16 Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + D+EV G ARF +EG P P+++W+KD+ + ES H Y+E+ CSL+ Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN-ECSLV 1543 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1913 + D YTC A N GE +C AEL V +T E EG GE+E+ Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED 1591 Score = 78.2 bits (191), Expect = 7e-14 Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 1/97 (1%) Query: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863 +P + P F++ + D+EV+EG AARFDCKI G P P V W + ES + ++ D G Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GG 1117 Query: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 SL I+ V +D+ Y AVN+ G+A C+A+L VE Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154 Score = 64.7 bits (156), Expect = 8e-10 Identities = 59/230 (25%), Positives = 85/230 (36%), Gaps = 37/230 (16%) Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH--RNGQPITSGGRFLLDCGIR 86 L EAPA + P + + EG A + E QV W R G + L Sbjct: 1386 LEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDD 1444 Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146 + L I V D G TC A N G + +V L + + Sbjct: 1445 DQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------------------- 1484 Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206 P+F + + V V G+ RF+ + G+P P + W K V L S+ Sbjct: 1485 --------------PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSH 1530 Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256 VS + L + D GVYTC N +G+ S AEL++ +A Sbjct: 1531 VSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTA 1580 Score = 60.8 bits (146), Expect = 1e-08 Identities = 47/165 (28%), Positives = 71/165 (43%), Gaps = 18/165 (10%) Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ--PIQYARSTCEAGVAELHI 570 AP F LK+ AV G D L+ V GTP P + W +GQ P +C L + Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC------LWL 95 Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630 + +D G Y+C+A+N G+ SC A +TV E S +E ++ + T + L+ Sbjct: 96 RRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAED--DISDVQGTQRLELRDDG 153 Query: 631 DLKVMDGSQVTMT--------VQVSGNPPPEVIWLHNGNEIQESE 667 G T+ V+G +V W +G + E E Sbjct: 154 AFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQE 198 Score = 59.3 bits (142), Expect = 3e-08 Identities = 52/252 (20%), Positives = 87/252 (34%), Gaps = 47/252 (18%) Query: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF-IIL 1146 E R+ + + A LQDV V G+ L +C V+ + W G+ L+ + Sbjct: 958 EVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKM 1017 Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206 +G C + + +D G+Y C + CS ++TV Sbjct: 1018 HFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV------------------- 1058 Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266 + ++ P + ED +V G + K++GT P Sbjct: 1059 --------------------------RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPP 1092 Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326 TW F ++ESE++++ L I E G Y + N G L Sbjct: 1093 PVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL- 1151 Query: 1327 VVDKPDPPAGTP 1338 V++P A P Sbjct: 1152 YVEEPRTAASGP 1163 Score = 57.0 bits (136), Expect = 2e-07 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%) Query: 1771 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1830 K PTSP +LES +D + A E+P P F ++++ V G+ C Sbjct: 693 KGRRARPTSP----ELESSDDSYVS-----AGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743 Query: 1831 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890 I P P+V W KD ++R + + + + +L++ + D Y A N LG+ Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERH-TLLLREARAADAGSYMATATNELGQ 802 Query: 1891 ATCTAELIV 1899 ATC A L V Sbjct: 803 ATCAASLTV 811 Score = 57.0 bits (136), Expect = 2e-07 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 13/228 (5%) Query: 972 PPPKPATPDFRSVLG--GKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 1029 PPP+ + S L G+ L AE + A+A ++ ++ A +G A Sbjct: 749 PPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATAT-----NELGQA 803 Query: 1030 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1089 A +L +P + P + + + EE + + + N + Sbjct: 804 TCAASL----TVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRR 859 Query: 1090 RSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148 S++ AP FK L D V EG+ +++ +V +P + W N + ++ + + Sbjct: 860 SSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEE 919 Query: 1149 -EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195 EG LC + I A D G Y C A N+ G +C ++ V P S + Sbjct: 920 AEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRS 967 Score = 55.1 bits (131), Expect = 7e-07 Identities = 32/96 (33%), Positives = 42/96 (43%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F ++ D V EG +++G P P V W ++ Q +R + + E G C L Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 I D YTCKAVN G C A L V E Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964 Score = 53.1 bits (126), Expect = 2e-06 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 7/96 (7%) Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681 AP+FL+ L + V GS V + V VSG P P + W +G + L Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAP-------EPSCLW 94 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717 ++ +D G Y+C A N G +AVLTV E D Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGD 130 Score = 53.1 bits (126), Expect = 2e-06 Identities = 41/188 (21%), Positives = 74/188 (39%), Gaps = 4/188 (2%) Query: 343 SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAA 399 + + QA P + G + SG + R + P + GL ++ + Sbjct: 2509 NQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQ 2568 Query: 400 NRRIPMEGQRDSAFPK-FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE 458 + +S FP F K + Q + E + C + P P ++W + +R + Sbjct: 2569 EELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEP 2628 Query: 459 GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518 I V G L + +A R +G Y C+A+N G ++ S T+ V R+ P Sbjct: 2629 SVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQ 2688 Query: 519 VLKDCAVI 526 +D A++ Sbjct: 2689 TYQDTALV 2696 Score = 53.1 bits (126), Expect = 2e-06 Identities = 51/178 (28%), Positives = 79/178 (44%), Gaps = 14/178 (7%) Query: 1017 AQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSASKEELKKDVKND 1074 A +G P + +E G++ P E+ + G ++P ++ K S L V+ + Sbjct: 2512 AAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKD-KGLSPPNLSASVQEE 2570 Query: 1075 VNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN 1134 + GH RSES P F KL+D + EG+ L C ++ P I W + Sbjct: 2571 L----GHQYV-----RSESD-FPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKD 2620 Query: 1135 GKTLKTT-KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191 K+L++ II+S + +SI +A GLY+C A N G SC V V P Sbjct: 2621 KKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678 Score = 52.4 bits (124), Expect = 4e-06 Identities = 55/209 (26%), Positives = 80/209 (38%), Gaps = 45/209 (21%) Query: 368 GEERKRPAPPRPATFPTR-QPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVK 426 GE+ APP P P R + G G V+ A P F ++ V Sbjct: 9 GEDAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGA-------------PVFLRPLKNAAVC 55 Query: 427 ENQTVKFRCEVSGIPKPEVAWFLEGT--PVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484 V+ R VSG P+P + WF +G P E S L L + +D+G Sbjct: 56 AGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC----------LWLRRCGAQDAGV 105 Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE------------GQDFV 532 YSC A N +G+ SC L V + E A S ++ +E G D + Sbjct: 106 YSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTGGSDTL 165 Query: 533 L-------QCSVRGTPVPRITWLLNGQPI 554 + SV GT +++W +GQ + Sbjct: 166 VGTSLDTPPTSVTGTSEEQVSWWGSGQTV 194 Score = 49.7 bits (117), Expect = 3e-05 Identities = 26/94 (27%), Positives = 43/94 (45%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 AP F+ ++DV V G+ V P I+W + L + + E + CS+ Sbjct: 1484 APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLV 1543 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190 + +D G+Y C A+N AG+ C ++ V A Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577 Score = 49.3 bits (116), Expect = 4e-05 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 1750 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES-EEDVSQAFLEAVAEEKPHVK 1808 +AV G+ A + R +++G P+S L EK+ S E+ Q LE ++ Sbjct: 1137 SAVNTHGQAHCSAQLYVEEPRTAASG-PSSKL--EKMPSIPEEPEQGELERLSI------ 1187 Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + ++DLEV A +C++ G P P + WF + I+ S ++ D + L+ Sbjct: 1188 PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLV 1246 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1909 V Y N LG+A C A L V + G +G Sbjct: 1247 FPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDG 1287 Score = 48.5 bits (114), Expect = 6e-05 Identities = 26/85 (30%), Positives = 43/85 (50%) Query: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874 ++D++V G A F+C + G D EV W + ++ + + + C L+++ V Sbjct: 974 LQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 1033 Query: 1875 DDDAKYTCKAVNSLGEATCTAELIV 1899 DD YTCK + E TC+A L V Sbjct: 1034 DDSGVYTCKLSTAKDELTCSARLTV 1058 Score = 48.1 bits (113), Expect = 8e-05 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 7/124 (5%) Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188 K L P +S ++ + V + + PP F KL V+ EG+ C P Sbjct: 2556 KGLSPPNLSASVQEELGHQYVRSE----SDFPPVFHIKLKDQVLLEGEAATLLCLPAACP 2611 Query: 189 QPQVTWLKGNVPL--QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246 P ++W+K L +PS + VS K+G Q+L I + G+Y C N G + S Sbjct: 2612 APHISWMKDKKSLRSEPSV-IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670 Query: 247 ELSI 250 +++ Sbjct: 2671 TVAV 2674 Score = 46.6 bits (109), Expect = 2e-04 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 12/106 (11%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F + +++ V GS R + G P P + WF+D Q + + +C + Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA-------PEPSCLWL 95 Query: 1869 ISDVCGDDDA-KYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1913 CG DA Y+C A N G A+C A L V +E G+ E E++ Sbjct: 96 RR--CGAQDAGVYSCMAQNERGRASCEAVLTV--LEVGDSETAEDD 137 Score = 46.6 bits (109), Expect = 2e-04 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS----TCEAGVAELH 569 P F LKD ++EG+ L C P P I+W+ + + ++ S +C+ G L Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643 Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600 I A G Y C A N LG ++ S V V Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674 Score = 45.1 bits (105), Expect = 7e-04 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 7/101 (6%) Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156 AP F + L++ V G + L+ VS P ++ W +G+ L + E S + Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAP-----APEPSC--LW 94 Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197 + + +D G+Y C+A+N+ G+A C +TV + SE + Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAE 135 Score = 45.1 bits (105), Expect = 7e-04 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR--FLLDC 83 ++ L EAP F ++ + G TA+F V G P P + W+++ +T F+ + Sbjct: 1478 TLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE- 1536 Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126 SLV+ + +D G YTC A N +G EL V + Sbjct: 1537 --ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577 Score = 44.7 bits (104), Expect = 9e-04 Identities = 28/91 (30%), Positives = 38/91 (41%) Query: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 P F ++D ++EG AA C P P + W KD +S+R I +DG L Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643 Query: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 I Y C A N LG T + + V Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91 AP F+ P +N + G+ + V G P+P + W R+GQ LL L Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQ--------LLPAPAPEPSCL 93 Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 + +D G Y+C A N G LTV Sbjct: 94 WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125 Score = 42.7 bits (99), Expect = 0.003 Identities = 60/258 (23%), Positives = 101/258 (39%), Gaps = 21/258 (8%) Query: 1176 AGQAECSCQVTVDDAPASENTKAP-EMKSR---------RPKSSLPPVLGTESDATVKKK 1225 AG S + +A A+ + AP E +SR + K PP L A+V+++ Sbjct: 2515 AGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLS----ASVQEE 2570 Query: 1226 PAPK-TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284 + ++ PP +DQ + GE+ L +WMK +K ++ + Sbjct: 2571 LGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSV 2630 Query: 1285 KVENSENGSKL-TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343 + + ++G +L +I A + H G Y N LGS + + V P A Sbjct: 2631 IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTY 2690 Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKF 1402 + ++L L G S A +Y++E W +++ +NV L +F Sbjct: 2691 QDTALVLWKPGDS----RAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRF 2746 Query: 1403 RVRAINVYGTSEPSQESE 1420 RV N G S SE Sbjct: 2747 RVACANRAGQGPFSNSSE 2764 Score = 40.0 bits (92), Expect = 0.022 Identities = 26/93 (27%), Positives = 36/93 (38%) Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294 A P+ ED +V AGE+ V G W K + ES H+ EN Sbjct: 1482 AEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS 1541 Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327 L +L+ + G YT +N G + L V Sbjct: 1542 LVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1574 Score = 38.9 bits (89), Expect = 0.049 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 9/91 (9%) Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLE 219 P F L V G R ++G PQP + W + G + P+ S L Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC--------LW 94 Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250 + D GVY+C+ N G+AS A L++ Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125 Score = 37.7 bits (86), Expect = 0.11 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 8/89 (8%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F+ ++ G V + ++G P P++ W RDG+ L + L Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA--------PEPSCLW 94 Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSL 809 L++ AG Y + +N G SC+ L Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVL 123 Score = 34.3 bits (77), Expect = 1.2 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780 P F K + G++ + C A P P + W++D K+L + V + L Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643 Query: 781 LKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809 + + HAG YE N +G SC V++ Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674 Score = 33.1 bits (74), Expect = 2.7 Identities = 30/141 (21%), Positives = 54/141 (38%), Gaps = 20/141 (14%) Query: 1219 DATVKKKPAPKTPPKAAM-------------PPQIIQFPEDQKVRAGESVELFGKVTGTQ 1265 DA + P+P PPK A P ++ ++ V AG V L V+GT Sbjct: 11 DAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTP 70 Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325 + W + + + + S L + + G Y+ + +N+ G + L Sbjct: 71 QPSLRWFRDGQLLPAP-------APEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVL 123 Query: 1326 TVVDKPDPPAGTPCASDIRSS 1346 TV++ D SD++ + Sbjct: 124 TVLEVGDSETAEDDISDVQGT 144 Score = 32.0 bits (71), Expect = 6.0 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 13/101 (12%) Query: 1820 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH--FQIDYDEDGNCSLIISDVCGDDD 1877 VVEG A + + +VVW ++ E+R +++ +D L I V D Sbjct: 1401 VVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDM 1459 Query: 1878 AKYTCKAVNSLGEATCTA----------ELIVETMEEGEGE 1908 TC A N G TC+ E I+E +E G GE Sbjct: 1460 GALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE 1500 Score = 32.0 bits (71), Expect = 6.0 Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 1/91 (1%) Query: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 681 P+F L D +++G T+ + P P + W+ + ++ E + + L Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643 Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712 I G Y C A N G + + + V Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674 >gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo sapiens] Length = 476 Score = 198 bits (503), Expect = 5e-50 Identities = 103/298 (34%), Positives = 175/298 (58%), Gaps = 4/298 (1%) Query: 1468 ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDA 1527 E LGSG F +VF + ++ T K++A K K A ++ EI+++ + H +V D Sbjct: 27 EVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDI 86 Query: 1528 FEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLK 1587 +E + +V+++VSGGELF+RI++ TE++ ++Q+ V+Y+H+ GIVH DLK Sbjct: 87 YESTTHYYLVMQLVSGGELFDRILERGV-YTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 1588 PENIMCVN-KTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWS 1646 PEN++ + + ++I + DFGL++ +E G + GTP +VAPEV+ +P A D WS Sbjct: 146 PENLLYLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWS 204 Query: 1647 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKN 1706 IGVI YIL+ G PF + +++ + ++F+ +D+IS+ AKDFI +LL+KD Sbjct: 205 IGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNE 264 Query: 1707 RLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAM 1763 R C + L HPW+ +T + + +++K A+ KW++ NA + + + M Sbjct: 265 RYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHM 322 >gi|4758194 serine/threonine kinase 17B [Homo sapiens] Length = 372 Score = 197 bits (502), Expect = 6e-50 Identities = 103/277 (37%), Positives = 174/277 (62%), Gaps = 9/277 (3%) Query: 1458 QKVSDFYDIEER-LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMN 1514 + ++FY + + LG GKF V + + K T + +A KF K + + I EI+++ Sbjct: 26 ENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLE 85 Query: 1515 CLHH-PKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL-TERECIKYMRQISEG 1572 P+++ + +E + I+++LE +GGE+F + E E+ +E + I+ ++QI EG Sbjct: 86 LAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEG 145 Query: 1573 VEYIHKQGIVHLDLKPENIMC--VNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAP 1630 V Y+H+ IVHLDLKP+NI+ + G IK++DFG++R++ +A L+ + GTPE++AP Sbjct: 146 VYYLHQNNIVHLDLKPQNILLSSIYPLGD-IKIVDFGMSRKIGHACELREIMGTPEYLAP 204 Query: 1631 EVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISD 1690 E++NY+PI ATDMW+IG+I Y+L++ SPF+G+++ ET N++ D+ +E F +S Sbjct: 205 EILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQ 264 Query: 1691 DAKDFISNLLKKDMKNRLDCTQCLQHPWLMK-DTKNM 1726 A DFI +LL K+ + R CL H WL + D +N+ Sbjct: 265 LATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENL 301 >gi|27901803 protein serine kinase H1 [Homo sapiens] Length = 424 Score = 191 bits (485), Expect = 6e-48 Identities = 103/305 (33%), Positives = 174/305 (57%), Gaps = 8/305 (2%) Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL 1516 + +V+ YDI+ +G G F +V R+ + TR+ +A K + + +E E+ ++ + Sbjct: 91 DPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRV 150 Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576 H ++Q V+ FE + + MV+E+ +GGELF+RII + TER+ + ++ + +GV Y+ Sbjct: 151 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKG-SFTERDATRVLQMVLDGVRYL 209 Query: 1577 HKQGIVHLDLKPENIMCVNK-TGTRIKLIDFGLA--RRLENAGSLKVLFGTPEFVAPEVI 1633 H GI H DLKPEN++ + T ++I + DFGLA R+ + +K GTPE++APEV+ Sbjct: 210 HALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVL 269 Query: 1634 NYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAK 1693 +P + DMW++GVI YIL+SG PF DN + + + E + +S+ AK Sbjct: 270 VRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAK 329 Query: 1694 DFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKL----SKDRMKKYMARRKWQKTG 1749 DFI LL D R+ Q L+HPW++ + K L S++ +K+ +R + K+ Sbjct: 330 DFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSA 389 Query: 1750 NAVRA 1754 + R+ Sbjct: 390 QSTRS 394 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.130 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,768,488 Number of Sequences: 37866 Number of extensions: 4284188 Number of successful extensions: 39621 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 799 Number of HSP's successfully gapped in prelim test: 732 Number of HSP's that attempted gapping in prelim test: 16599 Number of HSP's gapped (non-prelim): 13496 length of query: 1914 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1797 effective length of database: 13,817,196 effective search space: 24829501212 effective search space used: 24829501212 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.