Guide to the Human Genome
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Name: PHGDH Sequence: fasta or formatted (533aa) NCBI GI: 23308577
Description:

phosphoglycerate dehydrogenase

Referenced in:

Amino Acid Biosynthesis and Selected Derivatives
Additional Genes in Development

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.1         54           2
 C cysteine            2.4         13           2
 D aspartate           3.8         20           1
 E glutamate           5.8         31           2
 F phenylalanine       2.8         15           1
 G glycine             9.4         50           2
 H histidine           1.5          8           1
 I isoleucine          4.5         24           2
 K lysine              4.9         26           2
 L leucine            12.2         65           3
 M methionine          2.4         13           1
 N asparagine          3.6         19           1
 P proline             4.9         26           2
 Q glutamine           5.1         27           2
 R arginine            4.1         22           2
 S serine              6.0         32           2
 T threonine           6.6         35           2
 V valine              8.3         44           2
 W tryptophan          1.1          6           1
 Y tyrosine            0.6          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   phosphoglycerate dehydrogenase 
CTBP1                 0.115   C-terminal binding protein 1 isoform 2 
CTBP1                 0.115   C-terminal binding protein 1 isoform 1 
CTBP2                 0.110   C-terminal binding protein 2 isoform 1 
CTBP2                 0.110   C-terminal binding protein 2 isoform 1 
CTBP2                 0.110   C-terminal binding protein 2 isoform 2 
GRHPR                 0.105   glyoxylate reductase/hydroxypyruvate reductase 
GAPDHS                0.007   glyceraldehyde-3-phosphate dehydrogenase, spermatogen...
LAMA5                 0.005   laminin alpha 5 
SMPD3                 0.005   neutral sphingomyelin phosphodiesterase 3 
HBS1L                 0.005   Hsp70 subfamily B suppressor 1-like protein isoform...
LOC100128682          0.005   PREDICTED: hypothetical protein LOC100128682 
LOC100128682          0.005   PREDICTED: hypothetical protein LOC100128682 
LOC100128682          0.005   PREDICTED: hypothetical protein LOC100128682 
HBS1L                 0.005   Hsp70 subfamily B suppressor 1-like protein isoform 1...
NEDD1                 0.005   neural precursor cell expressed, developmentally do...
NEDD1                 0.005   neural precursor cell expressed, developmentally dow...
NEDD1                 0.005   neural precursor cell expressed, developmentally do...
C14orf4               0.005   chromosome 14 open reading frame 4 
ADAM15                0.004   a disintegrin and metalloproteinase domain 15 isofor...
ADAM15                0.004   a disintegrin and metalloproteinase domain 15 isofor...
ADAM15                0.004   a disintegrin and metalloproteinase domain 15 isofor...
ADAM15                0.004   a disintegrin and metalloproteinase domain 15 isofor...
ADAM15                0.004   a disintegrin and metalloproteinase domain 15 isofor...
ADAM15                0.004   a disintegrin and metalloproteinase domain 15 isofor...
DCD                   0.004   dermcidin preproprotein 
PKD1L2                0.004   polycystin 1-like 2 isoform c 
PKD1L2                0.004   polycystin 1-like 2 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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