Guide to the Human Genome
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Search of human proteins with 23200012

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo
sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo sap...   616   e-177
gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo sap...   609   e-174
gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo sa...   418   e-117
gi|223941836 abhydrolase domain containing 11 7 [Homo sapiens]        176   2e-44
gi|23200018 abhydrolase domain containing 11 isoform 5 [Homo sap...   175   5e-44
gi|218777837 abhydrolase domain containing 7 [Homo sapiens]            61   1e-09
gi|218777840 abhydrolase domain containing 9 [Homo sapiens]            55   6e-08
gi|13376164 abhydrolase domain containing 9 [Homo sapiens]             55   6e-08
gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]            53   3e-07
gi|189027141 abhydrolase domain containing 6 [Homo sapiens]            50   3e-06
gi|7706645 protein phosphatase methylesterase 1 [Homo sapiens]         46   5e-05
gi|18777795 serine hydrolase-like 2 [Homo sapiens]                     43   3e-04
gi|31542303 abhydrolase domain containing 5 [Homo sapiens]             39   0.008
gi|145611434 abhydrolase domain containing 8 [Homo sapiens]            36   0.038
gi|221316588 biphenyl hydrolase-like [Homo sapiens]                    35   0.084
gi|207028748 N-myc downstream regulated 1 [Homo sapiens]               35   0.084
gi|37655183 N-myc downstream regulated 1 [Homo sapiens]                35   0.084
gi|8923001 abhydrolase domain containing 10 [Homo sapiens]             35   0.11 
gi|50658087 abhydrolase domain containing 4 [Homo sapiens]             34   0.14 
gi|32130514 N-myc downstream-regulated gene 3 isoform b [Homo sa...    33   0.42 
gi|14165266 N-myc downstream-regulated gene 3 isoform a [Homo sa...    33   0.42 
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs...    32   0.54 
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso...    32   0.54 
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs...    32   0.71 
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs...    32   0.71 
gi|32528310 abhydrolase domain containing 12B isoform c [Homo sa...    32   0.93 
gi|32451492 abhydrolase domain containing 12B isoform b [Homo sa...    32   0.93 
gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]              31   1.2  
gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]               31   1.2  
gi|123173757 RAVER1 [Homo sapiens]                                     31   1.2  

>gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo
           sapiens]
          Length = 308

 Score =  616 bits (1588), Expect = e-177
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRLLDGEAALP 60
           MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRLLDGEAALP
Sbjct: 1   MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRLLDGEAALP 60

Query: 61  AVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMSQDLQDLL 120
           AVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMSQDLQDLL
Sbjct: 61  AVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMSQDLQDLL 120

Query: 121 PQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATYVAAMRAI 180
           PQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATYVAAMRAI
Sbjct: 121 PQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATYVAAMRAI 180

Query: 181 NIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALTQHLDKIL 240
           NIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALTQHLDKIL
Sbjct: 181 NIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALTQHLDKIL 240

Query: 241 AFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHADRPQDFI 300
           AFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHADRPQDFI
Sbjct: 241 AFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHADRPQDFI 300

Query: 301 AAIRGFLV 308
           AAIRGFLV
Sbjct: 301 AAIRGFLV 308


>gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo
           sapiens]
          Length = 315

 Score =  609 bits (1570), Expect = e-174
 Identities = 308/315 (97%), Positives = 308/315 (97%), Gaps = 7/315 (2%)

Query: 1   MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPR-------LL 53
           MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPR       LL
Sbjct: 1   MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRPLPLSYRLL 60

Query: 54  DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMS 113
           DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMS
Sbjct: 61  DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMS 120

Query: 114 QDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATY 173
           QDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATY
Sbjct: 121 QDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATY 180

Query: 174 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALT 233
           VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALT
Sbjct: 181 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALT 240

Query: 234 QHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHA 293
           QHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHA
Sbjct: 241 QHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHA 300

Query: 294 DRPQDFIAAIRGFLV 308
           DRPQDFIAAIRGFLV
Sbjct: 301 DRPQDFIAAIRGFLV 315


>gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo
           sapiens]
          Length = 258

 Score =  418 bits (1074), Expect = e-117
 Identities = 227/315 (72%), Positives = 235/315 (74%), Gaps = 64/315 (20%)

Query: 1   MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPR-------LL 53
           MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPR       LL
Sbjct: 1   MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRPLPLSYRLL 60

Query: 54  DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMS 113
           DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMS
Sbjct: 61  DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMS 120

Query: 114 QDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATY 173
           QDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQR   V + +  ++  V+   V      
Sbjct: 121 QDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRDMAVRQHLLTNLVEVDGRFVWR---- 176

Query: 174 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALT 233
                 +N+                        A+ QHL                     
Sbjct: 177 ------VNLD-----------------------ALTQHL--------------------- 186

Query: 234 QHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHA 293
              DKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHA
Sbjct: 187 ---DKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHA 243

Query: 294 DRPQDFIAAIRGFLV 308
           DRPQDFIAAIRGFLV
Sbjct: 244 DRPQDFIAAIRGFLV 258


>gi|223941836 abhydrolase domain containing 11 7 [Homo sapiens]
          Length = 184

 Score =  176 bits (446), Expect = 2e-44
 Identities = 89/97 (91%), Positives = 90/97 (92%), Gaps = 7/97 (7%)

Query: 1  MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEP-------RLL 53
          MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEP       RLL
Sbjct: 1  MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRPLPLSYRLL 60

Query: 54 DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRV 90
          DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRR+
Sbjct: 61 DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRI 97


>gi|23200018 abhydrolase domain containing 11 isoform 5 [Homo
          sapiens]
          Length = 97

 Score =  175 bits (443), Expect = 5e-44
 Identities = 89/96 (92%), Positives = 89/96 (92%), Gaps = 7/96 (7%)

Query: 1  MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEP-------RLL 53
          MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEP       RLL
Sbjct: 1  MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRPLPLSYRLL 60

Query: 54 DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRR 89
          DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRR
Sbjct: 61 DGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRR 96


>gi|218777837 abhydrolase domain containing 7 [Homo sapiens]
          Length = 362

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 61/264 (23%), Positives = 112/264 (42%), Gaps = 31/264 (11%)

Query: 55  GEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSP-HSPDMSYEI 111
           GE   P ++ LHG    +  ++   ++   ++  RV+ +D R +G  D+P H  +   + 
Sbjct: 89  GERGKPLMLLLHGF--PEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDC 146

Query: 112 MSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFA 171
           +  D++D+L  LG   CV++GH  GG  A L+A+  PE+V +LI ++         + F 
Sbjct: 147 LITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINF-----PHPNVFT 201

Query: 172 TYVAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDA 231
            Y+    A  +              E + S I D  V +HL T+     GR   ++  + 
Sbjct: 202 EYILRHPAQLLKSSYYYFFQIPWFPEFMFS-INDFKVLKHLFTSHSTGIGRKGCQLTTED 260

Query: 232 LTQHL-----------------DKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMR 274
           L  ++                 +     P +      PTL L G N  F+      E+ +
Sbjct: 261 LEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFME-VEMAEVTK 319

Query: 275 LFPR--AQMQTVPNAGHWIHADRP 296
           ++ +   ++  +  A HW+  D+P
Sbjct: 320 IYVKNYFRLTILSEASHWLQQDQP 343


>gi|218777840 abhydrolase domain containing 9 [Homo sapiens]
          Length = 360

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 59/262 (22%), Positives = 110/262 (41%), Gaps = 18/262 (6%)

Query: 60  PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSPHSPDM-SYEIMSQDL 116
           P ++FLHG    +  F+   ++   Q+   V+ VD R +G  D+P   D  + +++  D+
Sbjct: 98  PLMLFLHGF--PENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDI 155

Query: 117 QDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPV---ESTGVSHFATY 173
           +D++  LG   C++V H  G   A   ++  P LVER++ V  +P+   +   + H + +
Sbjct: 156 KDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQF 215

Query: 174 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVD-GRFVWRVN---- 228
             +        +LP    + L+      +   +  R+  +  L   +   F++  +    
Sbjct: 216 FRSHYMFLF--QLPWLPEKLLSMSDFQILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGG 273

Query: 229 -LDALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEI-MRLFP-RAQMQTVP 285
               L  + +    FP   +    PTL L G    ++       I  R  P R +   +P
Sbjct: 274 LTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILP 333

Query: 286 NAGHWIHADRPQDFIAAIRGFL 307
             GHWI    PQ+    +  FL
Sbjct: 334 GIGHWIPQSNPQEMHQYMWAFL 355


>gi|13376164 abhydrolase domain containing 9 [Homo sapiens]
          Length = 360

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 59/262 (22%), Positives = 110/262 (41%), Gaps = 18/262 (6%)

Query: 60  PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSPHSPDM-SYEIMSQDL 116
           P ++FLHG    +  F+   ++   Q+   V+ VD R +G  D+P   D  + +++  D+
Sbjct: 98  PLMLFLHGF--PENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDI 155

Query: 117 QDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPV---ESTGVSHFATY 173
           +D++  LG   C++V H  G   A   ++  P LVER++ V  +P+   +   + H + +
Sbjct: 156 KDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQF 215

Query: 174 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVD-GRFVWRVN---- 228
             +        +LP    + L+      +   +  R+  +  L   +   F++  +    
Sbjct: 216 FRSHYMFLF--QLPWLPEKLLSMSDFQILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGG 273

Query: 229 -LDALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEI-MRLFP-RAQMQTVP 285
               L  + +    FP   +    PTL L G    ++       I  R  P R +   +P
Sbjct: 274 LTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILP 333

Query: 286 NAGHWIHADRPQDFIAAIRGFL 307
             GHWI    PQ+    +  FL
Sbjct: 334 GIGHWIPQSNPQEMHQYMWAFL 355


>gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
          Length = 555

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 48/171 (28%), Positives = 79/171 (46%), Gaps = 17/171 (9%)

Query: 38  PSSSSGGRGGAEPRLLDGEAAL---PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVD 94
           PS  S G    +PR+      L   PAV   HG   S  ++      LAQ  G RVL +D
Sbjct: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ-AGYRVLAMD 292

Query: 95  ARNHGDSPHSPDMS---YEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELV 151
            + +G+S   P++     E++ +++   L +LGL   V +GH  GG     +AL  PE V
Sbjct: 293 MKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERV 352

Query: 152 ERLIAV---------DISPVESTGVSHFATYVAAMRAINIAD-ELPRSRAR 192
             + ++         ++SP+ES   +    Y    +   +A+ EL ++ +R
Sbjct: 353 RAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSR 403


>gi|189027141 abhydrolase domain containing 6 [Homo sapiens]
          Length = 337

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 57/263 (21%), Positives = 113/263 (42%), Gaps = 26/263 (9%)

Query: 60  PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSP--DMSYEIMSQDLQ 117
           P+++ LHG    K  + S+ K L +     ++ VD   H  +  S   D+S +   + + 
Sbjct: 72  PSILMLHGFSAHKDMWLSVVKFLPKNL--HLVCVDMPGHEGTTRSSLDDLSIDGQVKRIH 129

Query: 118 DLLPQLGL--VPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATYVA 175
             +  L L   P  +VG SMGG+ A + A   P  V  L  V  + ++ +  + F   + 
Sbjct: 130 QFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYSTDNQFVQRLK 189

Query: 176 AMRAINIADELPRSRARKLADEQLSSVIQ-----DMAVRQHLLTNLVEV---DGRFVWRV 227
            ++     +++P   +     E++S ++Q        V Q +L  LV+V      F  ++
Sbjct: 190 ELQGSAAVEKIPLIPS---TPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNNFYRKL 246

Query: 228 NLDALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNA 287
            L+ +++      +  Q  +    PT  + G   Q +  S    + +     Q++ + N 
Sbjct: 247 FLEIVSEK--SRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVELLENC 304

Query: 288 GHWIHADRPQ-------DFIAAI 303
           GH +  +RP+       DF+A++
Sbjct: 305 GHSVVMERPRKTAKLIIDFLASV 327


>gi|7706645 protein phosphatase methylesterase 1 [Homo sapiens]
          Length = 386

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 62/299 (20%), Positives = 119/299 (39%), Gaps = 57/299 (19%)

Query: 60  PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDS--PHSPDMSYEIMSQDLQ 117
           P ++ LHG   S  ++      +  +   R++ +D R+HG++   +  D+S E M++D+ 
Sbjct: 77  PVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVG 136

Query: 118 DLLPQLG---LVPCVVVGHSMGGKTAM----------LLALQRPELVERLIAVDISPVES 164
           +++  +      P +++GHSMGG  A+          LL L   ++VE      ++ +++
Sbjct: 137 NVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQN 196

Query: 165 TGVSHFATYVAAMRAINIADELPRSRARKLADEQLSSV--------IQDMAVRQHLLTNL 216
                  T+ +   AI  +  +   + R L   ++S V        I      + ++  +
Sbjct: 197 FLRGRPKTFKSLENAIEWS--VKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGI 254

Query: 217 VE------------------------VDGRFVWRVNLDALTQHLDKILAFPQRQESYLG- 251
           +E                         D  + WR+ L    ++ D    F      +L  
Sbjct: 255 IEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDG--WFRGLSNLFLSC 312

Query: 252 --PTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHADRPQDFIAAIRGFLV 308
             P L LL G  +         I ++  + QMQ +P  GH +H D P     A+  FL+
Sbjct: 313 PIPKLLLLAGVDRL---DKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLI 368


>gi|18777795 serine hydrolase-like 2 [Homo sapiens]
          Length = 314

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 32/119 (26%), Positives = 60/119 (50%), Gaps = 7/119 (5%)

Query: 60  PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPH-SPDMSYEIMS--QDL 116
           P V+ LHG   + ++F+ +  +L Q      + +D   HG S H SP + Y + +   ++
Sbjct: 33  PPVLCLHGWLDNASSFDRLIPLLPQDF--YYVAMDFGGHGLSSHYSPGVPYYLQTFVSEI 90

Query: 117 QDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVD--ISPVESTGVSHFATY 173
           + ++  L      ++GHS GG    +     PE+V++LI +D  +  +ES  + +  TY
Sbjct: 91  RRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTY 149


>gi|31542303 abhydrolase domain containing 5 [Homo sapiens]
          Length = 349

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 62/275 (22%), Positives = 108/275 (39%), Gaps = 52/275 (18%)

Query: 62  VVFLHGLFGS----KTNFNSIAKILAQQTGRRVLTVDARNHGDS--PHSPDMSYEIMSQ- 114
           +V LHG  G       NF  +       T R V   D    G S  P     + E+ +Q 
Sbjct: 78  LVLLHGFGGGLGLWALNFGDLC------TNRPVYAFDLLGFGRSSRPRFDSDAEEVENQF 131

Query: 115 --DLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAV---------DIS--- 160
              +++    LGL   +++GH++GG  A   +L+ P  V  LI V         D++   
Sbjct: 132 VESIEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVEPWGFPERPDLADQD 191

Query: 161 ---PVESTGVSHFATYVAAMRAINIADELPRSRARKLADE---QLSSVIQDMAVRQHLLT 214
              PV    +    T    +  + IA     S  ++L  +   + SS+ +D  V +++  
Sbjct: 192 RPIPVWIRALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYH 251

Query: 215 NLVEVDGRFVWRVNLD--------ALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHP 266
             V+         N+          + Q + K+   P    S +      + GNS     
Sbjct: 252 CNVQTPSGETAFKNMTIPYGWAKRPMLQRIGKM--HPDIPVSVIFGARSCIDGNS----- 304

Query: 267 SHHPEIMRLFPRAQMQTVP--NAGHWIHADRPQDF 299
                I  L P + ++T+    AGH+++AD+P++F
Sbjct: 305 --GTSIQSLRPHSYVKTIAILGAGHYVYADQPEEF 337


>gi|145611434 abhydrolase domain containing 8 [Homo sapiens]
          Length = 439

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 23/143 (16%)

Query: 37  APSSSSGGRGG---------------AEPRLLDGEAALPAVV--FLHGLFGSKTNFNSIA 79
           A S S  G GG                E R+   + A   VV  F+HG+ GS   +    
Sbjct: 136 AGSGSGSGSGGRRRRARRPKRTIHIDCEKRITSCKGAQADVVLFFIHGVGGSLAIWKEQL 195

Query: 80  KILAQQTGRRVLTVDARNHGDSPHSPDMS----YEIMSQDLQDLLPQLGLVPCVVVGHSM 135
               +  G  V+  D   HG S  +P ++    +  +++D++ +  +      V++GHS 
Sbjct: 196 DFFVR-LGYEVVAPDLAGHGASS-APQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSY 253

Query: 136 GGKTAMLLALQRPELVERLIAVD 158
           G      LA + P+LV ++I ++
Sbjct: 254 GVSFCTFLAHEYPDLVHKVIMIN 276


>gi|221316588 biphenyl hydrolase-like [Homo sapiens]
          Length = 291

 Score = 35.0 bits (79), Expect = 0.084
 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 8/101 (7%)

Query: 61  AVVFLHGLFGS-KTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSY-----EIMSQ 114
           AV+ L G+ GS +T+F    K L ++    V+  D R +G S   PD  +     E  ++
Sbjct: 62  AVLLLPGMLGSGETDFGPQLKNLNKKLFT-VVAWDPRGYGHS-RPPDRDFPADFFERDAK 119

Query: 115 DLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLI 155
           D  DL+  L      ++G S GG TA++ A + P  + +++
Sbjct: 120 DAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV 160


>gi|207028748 N-myc downstream regulated 1 [Homo sapiens]
          Length = 394

 Score = 35.0 bits (79), Expect = 0.084
 Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 90  VLTVDARNHGDSPHSPDMSYEIMSQD-LQDLLP----QLGLVPCVVVGHSMGGKTAMLLA 144
           V  VDA    D   S    Y   S D L ++LP    Q GL   + +G   G       A
Sbjct: 91  VCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFA 150

Query: 145 LQRPELVERLIAVDISP 161
           L  PE+VE L+ ++++P
Sbjct: 151 LNNPEMVEGLVLINVNP 167


>gi|37655183 N-myc downstream regulated 1 [Homo sapiens]
          Length = 394

 Score = 35.0 bits (79), Expect = 0.084
 Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 90  VLTVDARNHGDSPHSPDMSYEIMSQD-LQDLLP----QLGLVPCVVVGHSMGGKTAMLLA 144
           V  VDA    D   S    Y   S D L ++LP    Q GL   + +G   G       A
Sbjct: 91  VCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFA 150

Query: 145 LQRPELVERLIAVDISP 161
           L  PE+VE L+ ++++P
Sbjct: 151 LNNPEMVEGLVLINVNP 167


>gi|8923001 abhydrolase domain containing 10 [Homo sapiens]
          Length = 306

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 2/100 (2%)

Query: 60  PAVVFLHGLFGSKTNFNSIA-KILAQQTGRRVLTVDARNHGDSP-HSPDMSYEIMSQDLQ 117
           P ++F+ G         ++A +   +  G   +  D    G S  +S + +     +D+ 
Sbjct: 76  PGIIFIPGYLSYMNGTKALAIEEFCKSLGHACIRFDYSGVGSSDGNSEESTLGKWRKDVL 135

Query: 118 DLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAV 157
            ++  L   P ++VG S+GG   +  A+ RPE V  LI V
Sbjct: 136 SIIDDLADGPQILVGSSLGGWLMLHAAIARPEKVVALIGV 175


>gi|50658087 abhydrolase domain containing 4 [Homo sapiens]
          Length = 342

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 8/103 (7%)

Query: 86  TGRRVL-TVDARNHGDS-----PHSPDMSYEIMSQDLQDLLPQLGLVPCVVVGHSMGGKT 139
           + RR L T D    G S     P  P+ + +     ++     +G+   +++GHS+GG  
Sbjct: 92  SARRTLHTFDLLGFGRSSRPAFPRDPEGAEDEFVTSIETWRETMGIPSMILLGHSLGGFL 151

Query: 140 AMLLALQRPELVERLIAVDI--SPVESTGVSHFATYVAAMRAI 180
           A   +++ P+ V+ LI VD    P+  T  S      A ++A+
Sbjct: 152 ATSYSIKYPDRVKHLILVDPWGFPLRPTNPSEIRAPPAWVKAV 194


>gi|32130514 N-myc downstream-regulated gene 3 isoform b [Homo
           sapiens]
          Length = 363

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 6/100 (6%)

Query: 90  VLTVDARNHGDSPHSPDMSYEIMSQD-LQDLLP----QLGLVPCVVVGHSMGGKTAMLLA 144
           V  VDA    +   S    Y+  + D L ++LP     L L   + +G   G       A
Sbjct: 77  VCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFA 136

Query: 145 LQRPELVERLIAVDISPVESTGVSHFATYVAAMRAINIAD 184
           L  PELVE L+ +++ P     +   A+ ++ +   N+ D
Sbjct: 137 LNHPELVEGLVLINVDPCAKGWIDWAASKLSGL-TTNVVD 175


>gi|14165266 N-myc downstream-regulated gene 3 isoform a [Homo
           sapiens]
          Length = 375

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 6/100 (6%)

Query: 90  VLTVDARNHGDSPHSPDMSYEIMSQD-LQDLLP----QLGLVPCVVVGHSMGGKTAMLLA 144
           V  VDA    +   S    Y+  + D L ++LP     L L   + +G   G       A
Sbjct: 89  VCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFA 148

Query: 145 LQRPELVERLIAVDISPVESTGVSHFATYVAAMRAINIAD 184
           L  PELVE L+ +++ P     +   A+ ++ +   N+ D
Sbjct: 149 LNHPELVEGLVLINVDPCAKGWIDWAASKLSGL-TTNVVD 187


>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score = 32.3 bits (72), Expect = 0.54
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 91  LTVDARNHGDSPHSPDMSYEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPEL 150
           L V A + GD P S +MS  +   D  D  P++ L P +    S G + A   A +R  L
Sbjct: 530 LLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEI-LYPALPTDGSTGVELAPRSA-ERGYL 587

Query: 151 VERLIAVDISPVESTGVSH 169
           V +++AVD    ++  +S+
Sbjct: 588 VTKVVAVDRDSGQNAWLSY 606


>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score = 32.3 bits (72), Expect = 0.54
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 91  LTVDARNHGDSPHSPDMSYEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPEL 150
           L V A + GD P S +MS  +   D  D  P++ L P +    S G + A   A +R  L
Sbjct: 530 LLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEI-LYPALPTDGSTGVELAPRSA-ERGYL 587

Query: 151 VERLIAVDISPVESTGVSH 169
           V +++AVD    ++  +S+
Sbjct: 588 VTKVVAVDRDSGQNAWLSY 606


>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score = 32.0 bits (71), Expect = 0.71
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 91  LTVDARNHGDSPHSPDMSYEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPEL 150
           L V AR+ GD P S ++S  +   D  D  P++ L P +    S G + A L A +   L
Sbjct: 530 LKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEI-LYPALPTDGSTGVELAPLSA-EPGYL 587

Query: 151 VERLIAVDISPVESTGVSH 169
           V +++AVD    ++  +S+
Sbjct: 588 VTKVVAVDRDSGQNAWLSY 606


>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 823

 Score = 32.0 bits (71), Expect = 0.71
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 91  LTVDARNHGDSPHSPDMSYEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPEL 150
           L V AR+ GD P S ++S  +   D  D  P++ L P +    S G + A L A +   L
Sbjct: 530 LKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEI-LYPALPTDGSTGVELAPLSA-EPGYL 587

Query: 151 VERLIAVDISPVESTGVSH 169
           V +++AVD    ++  +S+
Sbjct: 588 VTKVVAVDRDSGQNAWLSY 606


>gi|32528310 abhydrolase domain containing 12B isoform c [Homo
           sapiens]
          Length = 285

 Score = 31.6 bits (70), Expect = 0.93
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 12/94 (12%)

Query: 49  EPRLLDGEAALPAVVFLHGLFGSKTNFN--SIAKILAQQTGRRVLTVDARNHGDSPHSPD 106
           E  L DG    P +V+LHG    +   +   + K+L+   G  VL+VD R  GDS   P 
Sbjct: 55  EAALRDGN---PIIVYLHGSAEHRAASHRLKLVKVLSDG-GFHVLSVDYRGFGDSTGKP- 109

Query: 107 MSYEIMSQD----LQDLLPQLGLVPCVVVGHSMG 136
            + E ++ D     +    + G+ P  + GHS+G
Sbjct: 110 -TEEGLTTDAICVYEWTKARSGITPVCLWGHSLG 142


>gi|32451492 abhydrolase domain containing 12B isoform b [Homo
           sapiens]
          Length = 255

 Score = 31.6 bits (70), Expect = 0.93
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 12/94 (12%)

Query: 49  EPRLLDGEAALPAVVFLHGLFGSKTNFN--SIAKILAQQTGRRVLTVDARNHGDSPHSPD 106
           E  L DG    P +V+LHG    +   +   + K+L+   G  VL+VD R  GDS   P 
Sbjct: 25  EAALRDGN---PIIVYLHGSAEHRAASHRLKLVKVLSDG-GFHVLSVDYRGFGDSTGKP- 79

Query: 107 MSYEIMSQD----LQDLLPQLGLVPCVVVGHSMG 136
            + E ++ D     +    + G+ P  + GHS+G
Sbjct: 80  -TEEGLTTDAICVYEWTKARSGITPVCLWGHSLG 112


>gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]
          Length = 303

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 126 VPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATY-VAAMRAINI 182
           +P  ++GHSMGG  A+L A +RP     ++   ISP+         T+ V A + +N+
Sbjct: 114 LPVFLLGHSMGGAIAILTAAERPGHFAGMVL--ISPLVLANPESATTFKVLAAKVLNL 169


>gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]
          Length = 313

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 126 VPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATY-VAAMRAINI 182
           +P  ++GHSMGG  A+L A +RP     ++   ISP+         T+ V A + +N+
Sbjct: 124 LPVFLLGHSMGGAIAILTAAERPGHFAGMVL--ISPLVLANPESATTFKVLAAKVLNL 179


>gi|123173757 RAVER1 [Homo sapiens]
          Length = 756

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/38 (50%), Positives = 22/38 (57%), Gaps = 5/38 (13%)

Query: 15  RAWRLPRE-GLGPHGPSFARVPVAPSS----SSGGRGG 47
           R +  PRE  LGPHGPS  ++   PS     SSGG GG
Sbjct: 613 RLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGG 650


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,754,525
Number of Sequences: 37866
Number of extensions: 526740
Number of successful extensions: 2112
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1978
Number of HSP's gapped (non-prelim): 151
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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