Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 23110962
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23110962 cathepsin S preproprotein [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23110962 cathepsin S preproprotein [Homo sapiens] 700 0.0
gi|4503151 cathepsin K preproprotein [Homo sapiens] 369 e-102
gi|23110960 cathepsin L2 preproprotein [Homo sapiens] 329 2e-90
gi|22202619 cathepsin L1 preproprotein [Homo sapiens] 323 1e-88
gi|4503155 cathepsin L1 preproprotein [Homo sapiens] 323 1e-88
gi|23110957 cathepsin H isoform b precursor [Homo sapiens] 204 7e-53
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 202 3e-52
gi|6042196 cathepsin F [Homo sapiens] 156 3e-38
gi|4557501 cathepsin O preproprotein [Homo sapiens] 141 9e-34
gi|23110964 cathepsin W preproprotein [Homo sapiens] 137 1e-32
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] 116 2e-26
gi|22538437 cathepsin B preproprotein [Homo sapiens] 107 1e-23
gi|22538435 cathepsin B preproprotein [Homo sapiens] 107 1e-23
gi|22538433 cathepsin B preproprotein [Homo sapiens] 107 1e-23
gi|22538431 cathepsin B preproprotein [Homo sapiens] 107 1e-23
gi|4503139 cathepsin B preproprotein [Homo sapiens] 107 1e-23
gi|22538442 cathepsin Z preproprotein [Homo sapiens] 105 4e-23
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa... 88 9e-18
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 81 1e-15
gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro... 64 1e-10
gi|4557367 bleomycin hydrolase [Homo sapiens] 30 3.9
gi|41152072 zinc finger, DHHC domain containing 5 [Homo sapiens] 29 5.1
gi|21704283 junctophilin 3 [Homo sapiens] 28 8.7
>gi|23110962 cathepsin S preproprotein [Homo sapiens]
Length = 331
Score = 700 bits (1807), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD 120
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD 120
Query: 121 WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 180
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
Sbjct: 121 WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 180
Query: 181 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE 240
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
Sbjct: 181 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE 240
Query: 241 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW 300
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
Sbjct: 241 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW 300
Query: 301 GHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
Sbjct: 301 GHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
>gi|4503151 cathepsin K preproprotein [Homo sapiens]
Length = 329
Score = 369 bits (947), Expect = e-102
Identities = 178/317 (56%), Positives = 224/317 (70%), Gaps = 6/317 (1%)
Query: 18 LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGM 77
L+ + LD HW LWKKT+ KQY K +E RRLIWEKNLK++ +HNLE S+G+H+Y+L M
Sbjct: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75
Query: 78 NHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGS 135
NHLGDMTSEEV+ M+ L+VP R + Y PDSVD+R+KG VT VK QG
Sbjct: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135
Query: 136 CGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 195
CG+CWAFS+VGALE QLK KTGKL++LS QNLVDC +E N GC GG+MT AFQY+ N
Sbjct: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---NDGCGGGYMTNAFQYVQKN 192
Query: 196 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 255
+GIDS+ +YPY ++ C Y+ +AA C Y E+P G E LK AVA GPVSV +DA
Sbjct: 193 RGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDAS 252
Query: 256 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 314
SF Y GVYY+ SC + N+NH VL VGYG G ++W++KNSWG N+G +GYI MAR
Sbjct: 253 LTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312
Query: 315 NKGNHCGIASFPSYPEI 331
NK N CGIA+ S+P++
Sbjct: 313 NKNNACGIANLASFPKM 329
>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
Length = 334
Score = 329 bits (843), Expect = 2e-90
Identities = 166/333 (49%), Positives = 222/333 (66%), Gaps = 10/333 (3%)
Query: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63
L L +SAV + D LD W+ WK T+ + Y NEE RR +WEKN+K + LHN
Sbjct: 7 LAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMKMIELHN 63
Query: 64 LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWRE 123
E+S G H + + MN GDMT+EE +M R ++++ ++ LP SVDWR+
Sbjct: 64 GEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFR-NQKFRKGKVFREPLFLDLPKSVDWRK 122
Query: 124 KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGG 183
KG VT VK Q CG+CWAFSA GALE Q+ KTGKLVSLS QNLVDCS + GN+GCNGG
Sbjct: 123 KGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQGCNGG 181
Query: 184 FMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVA 243
FM AFQY+ +N G+DS+ SYPY A+D+ C+Y + A + +T + G+E L +AVA
Sbjct: 182 FMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVA 241
Query: 244 NKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKN 298
GP+SV +DA H SF Y+SG+Y+EP C ++N++HGVLVVGYG + N +YWLVKN
Sbjct: 242 TVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKN 301
Query: 299 SWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
SWG +G GY+++A++K NHCGIA+ SYP +
Sbjct: 302 SWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 323 bits (828), Expect = 1e-88
Identities = 163/338 (48%), Positives = 220/338 (65%), Gaps = 19/338 (5%)
Query: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63
L+ A A L D +L+ W WK + + Y NEE RR +WEKN+K + LHN
Sbjct: 5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHN 63
Query: 64 LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL-----RVPSQWQRNITYKSNPNRILPDS 118
E+ G HS+ + MN GDMTSEE +M+ R +Q + Y++ P S
Sbjct: 64 QEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRS 117
Query: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
VDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+
Sbjct: 118 VDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNE 176
Query: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVL 238
GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L
Sbjct: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKAL 235
Query: 239 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEY 293
+AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + +Y
Sbjct: 236 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY 295
Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
WLVKNSWG +G GY++MA+++ NHCGIAS SYP +
Sbjct: 296 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 323 bits (828), Expect = 1e-88
Identities = 163/338 (48%), Positives = 220/338 (65%), Gaps = 19/338 (5%)
Query: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63
L+ A A L D +L+ W WK + + Y NEE RR +WEKN+K + LHN
Sbjct: 5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHN 63
Query: 64 LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL-----RVPSQWQRNITYKSNPNRILPDS 118
E+ G HS+ + MN GDMTSEE +M+ R +Q + Y++ P S
Sbjct: 64 QEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRS 117
Query: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
VDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+
Sbjct: 118 VDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNE 176
Query: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVL 238
GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L
Sbjct: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKAL 235
Query: 239 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEY 293
+AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + +Y
Sbjct: 236 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY 295
Query: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
WLVKNSWG +G GY++MA+++ NHCGIAS SYP +
Sbjct: 296 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
Length = 323
Score = 204 bits (520), Expect = 7e-53
Identities = 123/333 (36%), Positives = 177/333 (53%), Gaps = 27/333 (8%)
Query: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLH 62
L+C +C +++ + H + H +KTY EE RL + N + + H
Sbjct: 7 LLCAAELCVNSLEKFHFKSWMSKH----RKTYS------TEEYHHRLQTFASNWRKINAH 56
Query: 63 NLEHSMGMHSYDLGMNHLGDMTSEEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVD 120
N G H++ + +N DM+ E+ L S + S + N + P P SVD
Sbjct: 57 N----NGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGP---YPPSVD 109
Query: 121 WREKG-CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKG 179
WR+KG V+ VK QG+CG+CW FS GALE+ + + TGK++SL+ Q LVDC+ + + N G
Sbjct: 110 WRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCA-QDFNNHG 168
Query: 180 CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLK 239
C GG + AF+YI+ NKGI + +YPY+ D C++ + E+ +
Sbjct: 169 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 228
Query: 240 EAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC---TQNVNHGVLVVGYGDLNGKEYWLV 296
EAVA PVS + F +YR+G+Y SC VNH VL VGYG+ NG YW+V
Sbjct: 229 EAVALYNPVSFAFEVTQ-DFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIV 287
Query: 297 KNSWGHNFGEEGYIRMARNKGNHCGIASFPSYP 329
KNSWG +G GY + R K N CG+A+ SYP
Sbjct: 288 KNSWGPQWGMNGYFLIERGK-NMCGLAACASYP 319
>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
Length = 335
Score = 202 bits (515), Expect = 3e-52
Identities = 119/310 (38%), Positives = 167/310 (53%), Gaps = 19/310 (6%)
Query: 27 HWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTS 85
H+ W + K Y EE RL + N + + HN G H++ + +N DM+
Sbjct: 34 HFKSWMSKHRKTYS--TEEYHHRLQTFASNWRKINAHN----NGNHTFKMALNQFSDMSF 87
Query: 86 EEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKG-CVTEVKYQGSCGACWAF 142
E+ L S + S + N + P P SVDWR+KG V+ VK QG+CG+CW F
Sbjct: 88 AEIKHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTF 144
Query: 143 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 202
S GALE+ + + TGK++SL+ Q LVDC+ + + N GC GG + AF+YI+ NKGI +
Sbjct: 145 STTGALESAIAIATGKMLSLAEQQLVDCA-QDFNNHGCQGGLPSQAFEYILYNKGIMGED 203
Query: 203 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 262
+YPY+ D C++ + E+ + EAVA PVS + F +Y
Sbjct: 204 TYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQ-DFMMY 262
Query: 263 RSGVYYEPSC---TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNH 319
R+G+Y SC VNH VL VGYG+ NG YW+VKNSWG +G GY + R K N
Sbjct: 263 RTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NM 321
Query: 320 CGIASFPSYP 329
CG+A+ SYP
Sbjct: 322 CGLAACASYP 331
>gi|6042196 cathepsin F [Homo sapiens]
Length = 484
Score = 156 bits (394), Expect = 3e-38
Identities = 91/295 (30%), Positives = 150/295 (50%), Gaps = 9/295 (3%)
Query: 34 TYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMS 93
TY + Y+ K E R ++ N+ V ++ ++ + G+ D+T EE ++
Sbjct: 193 TYNRTYESKEEARWRLSVFVNNM--VRAQKIQ-ALDRGTAQYGVTKFSDLTEEEFRTIYL 249
Query: 94 SLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLK 153
+ + + + + + P DWR KG VT+VK QG CG+CWAFS G +E Q
Sbjct: 250 NTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWF 309
Query: 154 LKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKC 213
L G L+SLS Q L+DC +K C GG + A+ I + G++++ Y Y+ Q C
Sbjct: 310 LNQGTLLSLSEQELLDCDKM---DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSC 366
Query: 214 QYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT 273
+ ++ + EL E L +A +GP+SV ++A F+ + P C+
Sbjct: 367 NFSAEKAKVYINDSVELSQ-NEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCS 425
Query: 274 Q-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327
++H VL+VGYG+ + +W +KNSWG ++GE+GY + R G CG+ + S
Sbjct: 426 PWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSG-ACGVNTMAS 479
>gi|4557501 cathepsin O preproprotein [Homo sapiens]
Length = 321
Score = 141 bits (355), Expect = 9e-34
Identities = 90/255 (35%), Positives = 133/255 (52%), Gaps = 16/255 (6%)
Query: 76 GMNHLGDMTSEEVMSLMSSLRVPSQWQRNIT--YKSNPNRILPDSVDWREKGCVTEVKYQ 133
G+N + EE ++ + PS++ R + S PN LP DWR+K VT+V+ Q
Sbjct: 68 GINQFSYLFPEEFKAIYLRSK-PSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQ 126
Query: 134 GSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYII 193
CG CWAFS VGA+E+ +K L LS Q ++DCS Y N GCNGG A ++
Sbjct: 127 QMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS---YNNYGCNGGSTLNALNWL- 182
Query: 194 DNK---GIDSDASYPYKAMDQKCQYDS-KYRAATCSKYTELPYG-REDVLKEAVANKGPV 248
NK + D+ YP+KA + C Y S + + Y+ + +ED + +A+ GP+
Sbjct: 183 -NKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPL 241
Query: 249 SVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEG 308
V VDA S+ Y G+ + NH VL+ G+ YW+V+NSWG ++G +G
Sbjct: 242 VVIVDA--VSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWGVDG 299
Query: 309 YIRMARNKGNHCGIA 323
Y + + N CGIA
Sbjct: 300 YAHV-KMGSNVCGIA 313
>gi|23110964 cathepsin W preproprotein [Homo sapiens]
Length = 376
Score = 137 bits (345), Expect = 1e-32
Identities = 94/303 (31%), Positives = 144/303 (47%), Gaps = 44/303 (14%)
Query: 59 VMLHNLEHSMGMHSYDLGMNHLG-----DMTSEEVMSLMSSLR----VPSQWQRNITYKS 109
+ HNL + + DLG G D+T EE L R VPS +
Sbjct: 65 IFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGRE--IRSE 122
Query: 110 NPNRILPDSVDWRE-KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV 168
P +P S DWR+ G ++ +K Q +C CWA +A G +E ++ V +S Q L+
Sbjct: 123 EPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELL 182
Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPY--KAMDQKCQYDSKYRAATCSK 226
DC + G+ GC+GGF+ AF +++N G+ S+ YP+ K +C + KY+ +
Sbjct: 183 DCG--RCGD-GCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRC-HPKKYQKVAWIQ 238
Query: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT---QNVNHGVLVV 283
+ E + + +A GP++V ++ + LYR GV T Q V+H VL+V
Sbjct: 239 DFIMLQNNEHRIAQYLATYGPITVTINMK--PLQLYRKGVIKATPTTCDPQLVDHSVLLV 296
Query: 284 GYGDLNGKE--------------------YWLVKNSWGHNFGEEGYIRMARNKGNHCGIA 323
G+G + +E YW++KNSWG +GE+GY R+ R N CGI
Sbjct: 297 GFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG-SNTCGIT 355
Query: 324 SFP 326
FP
Sbjct: 356 KFP 358
>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
Length = 463
Score = 116 bits (291), Expect = 2e-26
Identities = 76/227 (33%), Positives = 118/227 (51%), Gaps = 22/227 (9%)
Query: 115 LPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVS--LSAQNLVD 169
LP S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V
Sbjct: 231 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 290
Query: 170 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 229
CS +Y +GC GGF + G+ +A +PY D C+ S+Y
Sbjct: 291 CS--QYA-QGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHY 347
Query: 230 LP--YG--REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT------QNVNHG 279
+ YG E ++K + + GP++V + + F Y+ G+Y+ + NH
Sbjct: 348 VGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNHA 406
Query: 280 VLVVGYG--DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIAS 324
VL+VGYG +G +YW+VKNSWG +GE GY R+ R + C I S
Sbjct: 407 VLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIES 452
>gi|22538437 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 107 bits (268), Expect = 1e-23
Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%)
Query: 115 LPDSVDWREKG----CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168
LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+
Sbjct: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139
Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221
C G+ GCNGG+ A+ + KG+ S Y PY + +
Sbjct: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197
Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255
T CSK E Y +D++ E N GPV G +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255
Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315
+ F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315
Query: 316 KGNHCGIAS 324
+ +HCGI S
Sbjct: 316 Q-DHCGIES 323
>gi|22538435 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 107 bits (268), Expect = 1e-23
Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%)
Query: 115 LPDSVDWREKG----CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168
LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+
Sbjct: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139
Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221
C G+ GCNGG+ A+ + KG+ S Y PY + +
Sbjct: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197
Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255
T CSK E Y +D++ E N GPV G +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255
Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315
+ F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315
Query: 316 KGNHCGIAS 324
+ +HCGI S
Sbjct: 316 Q-DHCGIES 323
>gi|22538433 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 107 bits (268), Expect = 1e-23
Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%)
Query: 115 LPDSVDWREKG----CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168
LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+
Sbjct: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139
Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221
C G+ GCNGG+ A+ + KG+ S Y PY + +
Sbjct: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197
Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255
T CSK E Y +D++ E N GPV G +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255
Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315
+ F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315
Query: 316 KGNHCGIAS 324
+ +HCGI S
Sbjct: 316 Q-DHCGIES 323
>gi|22538431 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 107 bits (268), Expect = 1e-23
Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%)
Query: 115 LPDSVDWREKG----CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168
LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+
Sbjct: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139
Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221
C G+ GCNGG+ A+ + KG+ S Y PY + +
Sbjct: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197
Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255
T CSK E Y +D++ E N GPV G +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255
Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315
+ F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315
Query: 316 KGNHCGIAS 324
+ +HCGI S
Sbjct: 316 Q-DHCGIES 323
>gi|4503139 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 107 bits (268), Expect = 1e-23
Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%)
Query: 115 LPDSVDWREKG----CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 168
LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+
Sbjct: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139
Query: 169 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 221
C G+ GCNGG+ A+ + KG+ S Y PY + +
Sbjct: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197
Query: 222 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 255
T CSK E Y +D++ E N GPV G +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255
Query: 256 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 315
+ F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315
Query: 316 KGNHCGIAS 324
+ +HCGI S
Sbjct: 316 Q-DHCGIES 323
>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
Length = 303
Score = 105 bits (263), Expect = 4e-23
Identities = 75/224 (33%), Positives = 109/224 (48%), Gaps = 36/224 (16%)
Query: 115 LPDSVDWREKGCVTEVKYQGS------CGACWAFSAVGALEAQLKLKT-GKLVS--LSAQ 165
LP S DWR V + CG+CWA ++ A+ ++ +K G S LS Q
Sbjct: 62 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 121
Query: 166 NLVDCSTEKYGNKG-CNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATC 224
N++DC GN G C GG + + Y + GI + Y+A DQ+C D + TC
Sbjct: 122 NVIDC-----GNAGSCEGGNDLSVWDYAHQH-GIPDETCNNYQAKDQEC--DKFNQCGTC 173
Query: 225 SKYTELPY----------------GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY 268
+++ E GRE ++ E AN GP+S G+ A Y G+Y
Sbjct: 174 NEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATE-RLANYTGGIYA 231
Query: 269 EPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRM 312
E T +NH V V G+G +G EYW+V+NSWG +GE G++R+
Sbjct: 232 EYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
sapiens]
Length = 467
Score = 88.2 bits (217), Expect = 9e-18
Identities = 74/260 (28%), Positives = 115/260 (44%), Gaps = 50/260 (19%)
Query: 110 NPNRILPDSVDWREK--GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT-GKLVS-LSAQ 165
NP +LP + + EK + E QG+C WAFS ++ + + G + LS Q
Sbjct: 198 NPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQ 257
Query: 166 NLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQK-------CQYDSK 218
NL+ C T + +GC GG + A+ + + +G+ SD YP+ ++ C S+
Sbjct: 258 NLLSCDTHQ--QQGCRGGRLDGAW-WFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSR 314
Query: 219 Y-----RAATC----------SKYTELPYGR-----EDVLKEAVANKGPVSVGVDARHPS 258
R AT Y P R ++++KE + N GPV ++ H
Sbjct: 315 AMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN-GPVQALMEV-HED 372
Query: 259 FFLYRSGVYYEPSCT--------QNVNHGVLVVGYG-----DLNGKEYWLVKNSWGHNFG 305
FFLY+ G+Y + ++ H V + G+G D +YW NSWG +G
Sbjct: 373 FFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWG 432
Query: 306 EEGYIRMARNKGNHCGIASF 325
E G+ R+ R N C I SF
Sbjct: 433 ERGHFRIVRGV-NECDIESF 451
>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
Length = 476
Score = 81.3 bits (199), Expect = 1e-15
Identities = 63/221 (28%), Positives = 97/221 (43%), Gaps = 44/221 (19%)
Query: 133 QGSCGACWAFS--AVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQ 190
Q +C A WAFS +V A ++ K +LS QNL+ C + GCN G + A+
Sbjct: 237 QKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKN--RHGCNSGSIDRAWW 294
Query: 191 YIIDNKGIDSDASYPY----KAMDQKCQYDSKY--------------------RAATCSK 226
Y+ +G+ S A YP A + C S+ R CS
Sbjct: 295 YL-RKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSP 353
Query: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVN--------H 278
+ +++KE + N GPV + R FF Y++G+Y + T + H
Sbjct: 354 PYRVSSNETEIMKEIMQN-GPVQAIMQVRE-DFFHYKTGIYRHVTSTNKESEKYRKLQTH 411
Query: 279 GVLVVGYGDLNG-----KEYWLVKNSWGHNFGEEGYIRMAR 314
V + G+G L G +++W+ NSWG ++GE GY R+ R
Sbjct: 412 AVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILR 452
>gi|239744067 PREDICTED: similar to Putative cathepsin L-like
protein 6 [Homo sapiens]
Length = 81
Score = 64.3 bits (155), Expect = 1e-10
Identities = 36/81 (44%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
Query: 56 LKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRIL 115
+K HN E+S G HS+ + MN GDMT+EE +M+ Q+Q++ K R+L
Sbjct: 1 MKMTEQHNQEYSQGKHSFTMAMNTFGDMTTEEFRQVMNGF----QYQKHRNGKQFQERLL 56
Query: 116 ---PDSVDWREKGCVTEVKYQ 133
P SVDWREKG VT VK Q
Sbjct: 57 LEIPTSVDWREKGYVTPVKDQ 77
>gi|4557367 bleomycin hydrolase [Homo sapiens]
Length = 455
Score = 29.6 bits (65), Expect = 3.9
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 294 WLVKNSWGHNFGEEGYIRM 312
W V+NSWG + G +GY+ M
Sbjct: 392 WRVENSWGEDHGHKGYLCM 410
>gi|41152072 zinc finger, DHHC domain containing 5 [Homo sapiens]
Length = 715
Score = 29.3 bits (64), Expect = 5.1
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 6/102 (5%)
Query: 218 KYRAATCSKYTE--LPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN 275
KYR S T +P+ L + K P S+ +RHPS YRS EP ++
Sbjct: 353 KYRPGYSSSSTSAAMPHSSSAKLSRGDSLKEPTSIAESSRHPS---YRSEPSLEPESFRS 409
Query: 276 VNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKG 317
G +G +K++ G F E G ++ R++G
Sbjct: 410 PTFGKSFHFDPLSSGSRSSSLKSAQGTGF-ELGQLQSIRSEG 450
>gi|21704283 junctophilin 3 [Homo sapiens]
Length = 748
Score = 28.5 bits (62), Expect = 8.7
Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 7/63 (11%)
Query: 260 FLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNF-GEEGYIRMARNKGN 318
+ + SG Y+ + Q HG+ L K W+ K W H F G G A N
Sbjct: 53 YTWPSGNTYQGTWAQGKRHGI------GLESKGKWVYKGEWTHGFKGRYGVRECAGNGAK 106
Query: 319 HCG 321
+ G
Sbjct: 107 YEG 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,027,744
Number of Sequences: 37866
Number of extensions: 550670
Number of successful extensions: 1269
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1190
Number of HSP's gapped (non-prelim): 25
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.