Search of human proteins with 23110925

Search of human proteins with 23110925

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23110925 proteasome beta 6 subunit [Homo sapiens]
         (239 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23110925 proteasome beta 6 subunit [Homo sapiens]                  480   e-136
gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo...   265   3e-71
gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo ...   265   3e-71
gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]        103   1e-22
gi|153791216 proteasome beta 11 subunit [Homo sapiens]                102   2e-22
gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]         102   2e-22
gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Hom...    99   4e-21
gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo...    99   4e-21
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]        97   9e-21
gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]        69   5e-12
gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]        63   3e-10
gi|22538465 proteasome beta 3 subunit [Homo sapiens]                   60   2e-09
gi|4506193 proteasome beta 1 subunit [Homo sapiens]                    53   3e-07
gi|4506195 proteasome beta 2 subunit [Homo sapiens]                    43   2e-04
gi|22538467 proteasome beta 4 subunit [Homo sapiens]                   39   0.005
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            30   1.4  
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            30   1.4  
gi|38570064 hypothetical protein LOC136895 [Homo sapiens]              30   1.8  
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            30   2.4  
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            30   2.4  
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            30   2.4  
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            29   3.2  
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            29   3.2  
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    29   3.2  
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            29   3.2  
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            29   3.2  
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi...    28   9.2  

>gi|23110925 proteasome beta 6 subunit [Homo sapiens]
          Length = 239

 Score =  480 bits (1236), Expect = e-136
 Identities = 239/239 (100%), Positives = 239/239 (100%)

Query: 1   MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYI 60
           MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYI
Sbjct: 1   MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYI 60

Query: 61  ANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEM 120
           ANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEM
Sbjct: 61  ANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEM 120

Query: 121 CYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREG 180
           CYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREG
Sbjct: 121 CYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREG 180

Query: 181 MTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA 239
           MTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA
Sbjct: 181 MTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA 239


>gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo
           sapiens]
          Length = 209

 Score =  265 bits (677), Expect = 3e-71
 Identities = 126/202 (62%), Positives = 160/202 (79%), Gaps = 1/202 (0%)

Query: 30  EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89
           EV TGTTIMAV+FDGGVV+G+DSR + G  + NRV DKL+P+H+RI+C  SGSAAD QAV
Sbjct: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65

Query: 90  ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVP 149
           AD   YQL  H IEL EPPLV  AA++ + + Y+YREDL A +++AGWD +EGGQVY   
Sbjct: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGT- 124

Query: 150 MGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIR 209
           +GGM+ RQ FAIGGSGS++IYGYVDA Y+ GM+ EEC +FT +A+ALAM RDGSSGGVI 
Sbjct: 125 LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIY 184

Query: 210 LAAIAESGVERQVLLGDQIPKF 231
           L  I  +GV+ +V+LG+++PKF
Sbjct: 185 LVTITAAGVDHRVILGNELPKF 206


>gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo
           sapiens]
          Length = 219

 Score =  265 bits (677), Expect = 3e-71
 Identities = 126/202 (62%), Positives = 160/202 (79%), Gaps = 1/202 (0%)

Query: 30  EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89
           EV TGTTIMAV+FDGGVV+G+DSR + G  + NRV DKL+P+H+RI+C  SGSAAD QAV
Sbjct: 16  EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 75

Query: 90  ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVP 149
           AD   YQL  H IEL EPPLV  AA++ + + Y+YREDL A +++AGWD +EGGQVY   
Sbjct: 76  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGT- 134

Query: 150 MGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIR 209
           +GGM+ RQ FAIGGSGS++IYGYVDA Y+ GM+ EEC +FT +A+ALAM RDGSSGGVI 
Sbjct: 135 LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIY 194

Query: 210 LAAIAESGVERQVLLGDQIPKF 231
           L  I  +GV+ +V+LG+++PKF
Sbjct: 195 LVTITAAGVDHRVILGNELPKF 216


>gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]
          Length = 277

 Score =  103 bits (257), Expect = 1e-22
 Identities = 60/187 (32%), Positives = 96/187 (51%), Gaps = 1/187 (0%)

Query: 33  TGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADA 92
           TGTTI  V +  G+VLGAD+R T G  +A++   K+  I   I+CC +G+AADT      
Sbjct: 42  TGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQL 101

Query: 93  VTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGG 152
           ++  L  HS+     P V TA  + K+M +RY+  + A +++ G D   G  +YS+   G
Sbjct: 102 ISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVD-VTGPHLYSIYPHG 160

Query: 153 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAA 212
              +  +   GSGS       +  +R  M +EE     + A+A  +  D  SG  I L  
Sbjct: 161 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCV 220

Query: 213 IAESGVE 219
           I+++ ++
Sbjct: 221 ISKNKLD 227


>gi|153791216 proteasome beta 11 subunit [Homo sapiens]
          Length = 300

 Score =  102 bits (255), Expect = 2e-22
 Identities = 63/187 (33%), Positives = 95/187 (50%), Gaps = 2/187 (1%)

Query: 34  GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAV 93
           GTT +A +F  GV+  AD+R++ GSY+A   + K+ P+H  +    SG++AD       +
Sbjct: 49  GTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVL 108

Query: 94  TYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSVPMGG 152
             +L    +   + P V +AA L   M  +YR  DL     + GWD + G +++ V   G
Sbjct: 109 QRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWD-RSGPELFYVYSDG 167

Query: 153 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAA 212
             ++      GSGS Y YG +D  YR  M+ +E       A+A A  RD  SGG + L  
Sbjct: 168 TRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFH 227

Query: 213 IAESGVE 219
           + ESG E
Sbjct: 228 VRESGWE 234


>gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]
          Length = 263

 Score =  102 bits (255), Expect = 2e-22
 Identities = 66/205 (32%), Positives = 97/205 (47%), Gaps = 6/205 (2%)

Query: 14  APAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHD 73
           AP WG     P+    E+  GTT +A +F  GV++ ADSR T G+YIA++   K+  I+ 
Sbjct: 43  APGWG----VPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINP 98

Query: 74  RIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGI 132
            +    +G AAD       +  Q   + +   E   V  A+ L   M Y+Y+   L  G 
Sbjct: 99  YLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGT 158

Query: 133 IIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTAN 192
           +I GWD +  G  Y    G  +   +F++ GSGS Y YG +D  Y   +  E+       
Sbjct: 159 MICGWDKRGPGLYYVDSEGNRISGATFSV-GSGSVYAYGVMDRGYSYDLEVEQAYDLARR 217

Query: 193 ALALAMERDGSSGGVIRLAAIAESG 217
           A+  A  RD  SGG + L  + E G
Sbjct: 218 AIYQATYRDAYSGGAVNLYHVREDG 242


>gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Homo
           sapiens]
          Length = 276

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 62/189 (32%), Positives = 95/189 (50%), Gaps = 2/189 (1%)

Query: 30  EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89
           E++ GTT +A +F  GV+   DSR + GSYI+    +K+  I+  +    SG AAD Q  
Sbjct: 68  EMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYW 127

Query: 90  ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSV 148
              +  +   + +   E   V  A+ L   M  +YR   L  G +I GWD ++G  +Y V
Sbjct: 128 ERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWD-KKGPGLYYV 186

Query: 149 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVI 208
              G  +  +    GSG++Y YG +D+ YR  ++ EE       A+A A  RD  SGGV+
Sbjct: 187 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 246

Query: 209 RLAAIAESG 217
            +  + E G
Sbjct: 247 NMYHMKEDG 255


>gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo
           sapiens]
          Length = 272

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 62/189 (32%), Positives = 95/189 (50%), Gaps = 2/189 (1%)

Query: 30  EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89
           E++ GTT +A +F  GV+   DSR + GSYI+    +K+  I+  +    SG AAD Q  
Sbjct: 64  EMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYW 123

Query: 90  ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSV 148
              +  +   + +   E   V  A+ L   M  +YR   L  G +I GWD ++G  +Y V
Sbjct: 124 ERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWD-KKGPGLYYV 182

Query: 149 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVI 208
              G  +  +    GSG++Y YG +D+ YR  ++ EE       A+A A  RD  SGGV+
Sbjct: 183 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 242

Query: 209 RLAAIAESG 217
            +  + E G
Sbjct: 243 NMYHMKEDG 251


>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
          Length = 273

 Score = 97.4 bits (241), Expect = 9e-21
 Identities = 56/187 (29%), Positives = 91/187 (48%), Gaps = 1/187 (0%)

Query: 33  TGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADA 92
           TGTTI  + F  GV+LGAD+R T  S +A++  +K+  I  +I+CC +G AAD +     
Sbjct: 38  TGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRM 97

Query: 93  VTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGG 152
           V  ++  H++     P V T   + ++  +RY+  + A +I+ G D   G Q+Y V   G
Sbjct: 98  VASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVD-LTGPQLYGVHPHG 156

Query: 153 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAA 212
              R  F   GSG       ++  ++  MT E        A+   +  D  SGG +    
Sbjct: 157 SYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACV 216

Query: 213 IAESGVE 219
           I ++G +
Sbjct: 217 ITKTGAK 223


>gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]
          Length = 203

 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 42/126 (33%), Positives = 62/126 (49%), Gaps = 5/126 (3%)

Query: 14  APAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHD 73
           AP WG     P+    E+  GTT +A +F  GV++ ADSR T G+YIA++   K+  I+ 
Sbjct: 43  APGWG----VPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINP 98

Query: 74  RIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGI 132
            +    +G AAD       +  Q   + +   E   V  A+ L   M Y+Y+   L  G 
Sbjct: 99  YLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGT 158

Query: 133 IIAGWD 138
           +I GWD
Sbjct: 159 MICGWD 164


>gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]
          Length = 160

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 2/139 (1%)

Query: 80  SGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWD 138
           +G AAD       +  Q   + +   E   V  A+ L   M Y+Y+   L  G +I GWD
Sbjct: 2   AGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD 61

Query: 139 PQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAM 198
            +  G  Y    G  +   +F++G SGS Y YG +D  Y   +  E+       A+  A 
Sbjct: 62  KRGPGLYYVDSEGNRISGATFSVG-SGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQAT 120

Query: 199 ERDGSSGGVIRLAAIAESG 217
            RD  SGG + L  + E G
Sbjct: 121 YRDAYSGGAVNLYHVREDG 139


>gi|22538465 proteasome beta 3 subunit [Homo sapiens]
          Length = 205

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 4/179 (2%)

Query: 34  GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAV 93
           G  +MA++    V + AD R    + +      K+ P+ DR++   +G A D Q VA  +
Sbjct: 8   GGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRL 67

Query: 94  TYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQ-VYSVPM- 150
            ++L  + ++       +T  S+   + Y  R        +IAG DP+     + S+ + 
Sbjct: 68  KFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLI 127

Query: 151 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSG-GVI 208
           G  MV   F + G+ +  +YG  ++ +   M  +   +  + A+  A++RD  SG GVI
Sbjct: 128 GCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVI 186


>gi|4506193 proteasome beta 1 subunit [Homo sapiens]
          Length = 241

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 44/203 (21%), Positives = 81/203 (39%), Gaps = 10/203 (4%)

Query: 31  VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVA 90
           V  G TI+A+  +   ++ +D+R + G  I  R + K   + D+     SG   D   + 
Sbjct: 34  VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93

Query: 91  DAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSVP 149
             +  +L  +    N+       A++   + Y  R        II G D +  G VYS  
Sbjct: 94  KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153

Query: 150 MGGMMVRQSFAIGGSGSSYIYGYVD---------ATYREGMTKEECLQFTANALALAMER 200
             G   R SF  GGS S+ +   +D               ++ +  ++   +    A ER
Sbjct: 154 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 213

Query: 201 DGSSGGVIRLAAIAESGVERQVL 223
           D  +G  +R+  + + G+  + +
Sbjct: 214 DVYTGDALRICIVTKEGIREETV 236


>gi|4506195 proteasome beta 2 subunit [Homo sapiens]
          Length = 201

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 5/139 (3%)

Query: 66  DKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEM----C 121
           DK+  + ++I     G A DT   A+ +   +  + +  N   L  TAA+ F       C
Sbjct: 33  DKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMR-NGYELSPTAAANFTRRNLADC 91

Query: 122 YRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGM 181
            R R      +++AG+D  EG  +Y +     + +  FA  G G+      +D  Y   +
Sbjct: 92  LRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTI 151

Query: 182 TKEECLQFTANALALAMER 200
           ++E  ++     L    +R
Sbjct: 152 SRERAVELLRKCLEELQKR 170


>gi|22538467 proteasome beta 4 subunit [Homo sapiens]
          Length = 264

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 44/197 (22%), Positives = 74/197 (37%), Gaps = 15/197 (7%)

Query: 33  TGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADA 92
           TGT+++ V+F+GGVV+ AD   + GS    R   ++  +++      SG  AD Q +   
Sbjct: 52  TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111

Query: 93  VTYQLGFHSI----ELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSV 148
           +   +    +        P  +H+  +            L   ++I G+   E    Y  
Sbjct: 112 LGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVD 171

Query: 149 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFT------ANALALAMERDG 202
            +G      S A G     Y         RE + K+  L  T         + +   RD 
Sbjct: 172 MLGVAYEAPSLATG-----YGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDA 226

Query: 203 SSGGVIRLAAIAESGVE 219
            S    ++A + E GVE
Sbjct: 227 RSYNRFQIATVTEKGVE 243


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1209

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  S   +   L  TA SL
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSL 1258


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1209

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  S   +   L  TA SL
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSL 1258


>gi|38570064 hypothetical protein LOC136895 [Homo sapiens]
          Length = 590

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 30/123 (24%), Positives = 49/123 (39%), Gaps = 10/123 (8%)

Query: 71  IHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMA 130
           IH R +CCR    AD  +          F+S EL+ P    T  +  ++     RE L  
Sbjct: 4   IHGRPYCCRELEGADILSNT--------FYSNELHNPLQTVTRPTASEDRYQELRESLQQ 55

Query: 131 GIIIAGWDPQEGGQV-YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQF 189
             +  G + + GG +  S+P       +   + G G  + YG+   T+   +  E+    
Sbjct: 56  CRLPWGAEREYGGIIPISLPEDHRPKYEPPRVMGKGHQH-YGFGGETWPRKLPVEQFYYL 114

Query: 190 TAN 192
           T N
Sbjct: 115 TQN 117


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 6/109 (5%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T  +          A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST---AGSETTTASTAGSETTTASTS 1219

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1220 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 6/109 (5%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T  +          A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST---AGSETTTASTAGSETTTASTS 1219

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1220 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 6/109 (5%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T  +          A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST---AGSETTTASTAGSETTTASTS 1219

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1220 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1209

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1184 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1230

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1231 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1279


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1209

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1209

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 16/109 (14%)

Query: 11   AGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP 70
            A  + A G EA T   E  E +T +T             A S TTT S   +  T   T 
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTAST-------------AGSETTTASTAGSETTTASTS 1209

Query: 71   IHDRIFCCRSGSAADTQAVADAVT---YQLGFHSIELNEPPLVHTAASL 116
              +    C +GS   T + A + T   + +G  +   +   L  TA SL
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258


>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
           sapiens]
          Length = 252

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 5/50 (10%)

Query: 163 GSGSSYIYGYVDATYREGMTKEECLQ----FTANALA-LAMERDGSSGGV 207
           GS   ++YG  D      +TKEECL+     T NA   LA  R+ +   V
Sbjct: 61  GSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSV 110


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,807,959
Number of Sequences: 37866
Number of extensions: 366152
Number of successful extensions: 886
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 824
Number of HSP's gapped (non-prelim): 84
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.