Guide to the Human Genome
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Search of human proteins with 229892345

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
         (978 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]       2070   0.0  
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]         2070   0.0  
gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]             489   e-138
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]            452   e-127
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]       229   7e-60
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]       229   7e-60
gi|166706915 GLIS family zinc finger 1 [Homo sapiens]                 224   4e-58
gi|110431364 GLIS family zinc finger 2 [Homo sapiens]                 197   4e-50
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]    178   2e-44
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]   177   6e-44
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]    176   1e-43
gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]    172   2e-42
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]     171   3e-42
gi|116014328 zinc finger protein 143 [Homo sapiens]                   129   1e-29
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]   120   6e-27
gi|21361146 zinc finger protein 76 (expressed in testis) [Homo s...   118   2e-26
gi|10863995 zinc finger protein 410 [Homo sapiens]                    115   2e-25
gi|28376656 zinc finger, X-linked, duplicated B [Homo sapiens]        110   5e-24
gi|28274709 zinc finger, X-linked, duplicated A [Homo sapiens]        110   5e-24
gi|65507817 Wilms tumor 1 isoform B [Homo sapiens]                    106   9e-23
gi|65507714 Wilms tumor 1 isoform A [Homo sapiens]                    106   9e-23
gi|48717244 zinc finger protein 782 [Homo sapiens]                    105   2e-22
gi|197313746 zinc finger protein 502 [Homo sapiens]                   103   6e-22
gi|197313744 zinc finger protein 502 [Homo sapiens]                   103   6e-22
gi|197313742 zinc finger protein 502 [Homo sapiens]                   103   6e-22
gi|21361857 zinc finger protein 502 [Homo sapiens]                    103   6e-22
gi|61676193 zinc finger protein 260 [Homo sapiens]                    103   1e-21
gi|148596977 zinc finger protein 31 [Homo sapiens]                    102   2e-21
gi|155029531 zinc finger protein 774 [Homo sapiens]                   102   2e-21
gi|65508004 Wilms tumor 1 isoform D [Homo sapiens]                    101   3e-21

>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
          Length = 978

 Score = 2070 bits (5364), Expect = 0.0
 Identities = 978/978 (100%), Positives = 978/978 (100%)

Query: 1   MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG 60
           MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG
Sbjct: 1   MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG 60

Query: 61  KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS 120
           KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS
Sbjct: 61  KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS 120

Query: 121 QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC 180
           QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC
Sbjct: 121 QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC 180

Query: 181 RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG 240
           RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG
Sbjct: 181 RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG 240

Query: 241 CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR 300
           CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR
Sbjct: 241 CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR 300

Query: 301 LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA 360
           LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA
Sbjct: 301 LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA 360

Query: 361 GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS 420
           GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS
Sbjct: 361 GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS 420

Query: 421 ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS 480
           ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS
Sbjct: 421 ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS 480

Query: 481 LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT 540
           LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT
Sbjct: 481 LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT 540

Query: 541 VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD 600
           VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD
Sbjct: 541 VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD 600

Query: 601 TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG 660
           TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG
Sbjct: 601 TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG 660

Query: 661 LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF 720
           LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF
Sbjct: 661 LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF 720

Query: 721 SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL 780
           SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL
Sbjct: 721 SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL 780

Query: 781 LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS 840
           LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS
Sbjct: 781 LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS 840

Query: 841 PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP 900
           PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP
Sbjct: 841 PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP 900

Query: 901 PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM 960
           PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM
Sbjct: 901 PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM 960

Query: 961 SVLLRSLPGETEFLNSSA 978
           SVLLRSLPGETEFLNSSA
Sbjct: 961 SVLLRSLPGETEFLNSSA 978


>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
          Length = 1106

 Score = 2070 bits (5364), Expect = 0.0
 Identities = 978/978 (100%), Positives = 978/978 (100%)

Query: 1    MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG 60
            MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG
Sbjct: 129  MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG 188

Query: 61   KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS 120
            KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS
Sbjct: 189  KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS 248

Query: 121  QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC 180
            QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC
Sbjct: 249  QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC 308

Query: 181  RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG 240
            RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG
Sbjct: 309  RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG 368

Query: 241  CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR 300
            CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR
Sbjct: 369  CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR 428

Query: 301  LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA 360
            LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA
Sbjct: 429  LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA 488

Query: 361  GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS 420
            GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS
Sbjct: 489  GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS 548

Query: 421  ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS 480
            ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS
Sbjct: 549  ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS 608

Query: 481  LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT 540
            LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT
Sbjct: 609  LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT 668

Query: 541  VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD 600
            VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD
Sbjct: 669  VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD 728

Query: 601  TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG 660
            TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG
Sbjct: 729  TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG 788

Query: 661  LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF 720
            LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF
Sbjct: 789  LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF 848

Query: 721  SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL 780
            SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL
Sbjct: 849  SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL 908

Query: 781  LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS 840
            LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS
Sbjct: 909  LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS 968

Query: 841  PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP 900
            PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP
Sbjct: 969  PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP 1028

Query: 901  PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM 960
            PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM
Sbjct: 1029 PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM 1088

Query: 961  SVLLRSLPGETEFLNSSA 978
            SVLLRSLPGETEFLNSSA
Sbjct: 1089 SVLLRSLPGETEFLNSSA 1106


>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
          Length = 1586

 Score =  489 bits (1260), Expect = e-138
 Identities = 427/1210 (35%), Positives = 539/1210 (44%), Gaps = 322/1210 (26%)

Query: 68   EGDMSSPNSTGIQDPLLG--MLDGREDLEREE-KREPESV-YETDCRWDGCSQEFDSQEQ 123
            +G +S   S G   PL    + D +EDL+R++ K+E E V YET+C W+ C++E+D+QEQ
Sbjct: 394  QGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQ 453

Query: 124  LVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKS 183
            LVHHIN+EHIHGE+KEFVC W  C+RE +PFKAQYMLVVHMRRHTGEKPHKCTFEGC K+
Sbjct: 454  LVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKA 513

Query: 184  YSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTK 243
            YSRLENLKTHLRSHTGEKPY+CEHEGC+KAFSNASDRAKHQNRTHSNEKPY+CK+PGCTK
Sbjct: 514  YSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTK 573

Query: 244  RYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKR--EREGGPIREES-- 299
            RYTDPSSLRKHVKTVHGPDAHVTK+ R D  L R P +            GGP   E+  
Sbjct: 574  RYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHL-RTPLLKENGDSEAGTEPGGPESTEASS 632

Query: 300  -----------RLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTE 348
                       R    E +   Q SPGAQSSCSS+ SP GSA N DSGVEM G   GS  
Sbjct: 633  TSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLG 692

Query: 349  DLSSLDEGPCIAGTG---------------LSTLRRLENLRLDQLHQLRPI--------G 385
            DL++LD+ P  A T                ++T+ R E L+ ++L  L+           
Sbjct: 693  DLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPH 752

Query: 386  TRGLKLPSLSHTGTTVSRRVGP----PVSL---------------------ERRSSSSSS 420
            TR  KLP L  +G+ +    G     P  L                     ERR SS+S+
Sbjct: 753  TRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTST 812

Query: 421  ISSAYTV------------SRRSSLASPFPPGSPPE------------------------ 444
            +SSAYTV            SRRSS ASP   G P                          
Sbjct: 813  VSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQC 872

Query: 445  NGASSLPGLMPAQHYLLRARYASARGGGTSPTAASSLDRI-----------------GGL 487
            +G S L  L PAQ Y LRA+YA+A  GG  PT    L+R+                  G 
Sbjct: 873  SGGSGLLNLTPAQQYSLRAKYAAAT-GGPPPTPLPGLERMSLRTRLALLDAPERTLPAGC 931

Query: 488  PMPPWRSRAE---------------YPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSL 532
            P P    R                 +P   P  G  RRASDP +  D  +  RVQRF S 
Sbjct: 932  PRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGG-ARRASDPVRRPDALSLPRVQRFHST 990

Query: 533  GCVH---TPPTVAGGG------QNFDPYLPTSVYSPQPPSITENAAMDA----------- 572
              V+    PP     G       + D  L    YSP+PPSI+EN AM+A           
Sbjct: 991  HNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPE 1050

Query: 573  --RGLQEE----PEVGTSMVGSGLNPYMD-----FPPTDTLGYG--------GPEG---- 609
               GL E+    P+     + +  +  +D       PT++ G+         G  G    
Sbjct: 1051 ADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRM 1110

Query: 610  -AAAEPYGARGP--GSLPLGPGPPTNYGPNPCPQQ------------ASYPDP------- 647
             AA    G   P  G   LG G P++   N  P Q            AS   P       
Sbjct: 1111 VAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGN 1170

Query: 648  -----TQETWGEFPSHS--GLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCP------- 693
                  +  +G++P +S  GL   P   GG  S  P L+        P QG P       
Sbjct: 1171 LAVVQQKPAFGQYPGYSPQGLQASP---GGLDSTQPHLQPRSGA---PSQGIPRVNYMQQ 1224

Query: 694  -----VGSDSTGLAPCLNAHPSEGPPHPQ-------PLFSHYPQ-----PSPPQYLQSGP 736
                  GS   G+   ++ H   G  HPQ          + +PQ     P+ P +L    
Sbjct: 1225 LRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQ 1284

Query: 737  YTQ--PPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELLWEGGGREDAPAQE 794
             T+  P P  + +  R     DS     G      V +Y Q    L         + +QE
Sbjct: 1285 QTEVAPDPTTMGNRHRELGVPDSAL--AGVPPPHPVQSYPQQSHHL-------AASMSQE 1335

Query: 795  PSYQSPKFLGGSQVSPSRAK-APVNTYGPGFGPNLPNHKSGSYPTPSPCH------ENFV 847
              +Q P  L   Q      +  P+     GFG  L   +    P+P+  H      +  +
Sbjct: 1336 GYHQVPSLLPARQPGFMEPQTGPMGVATAGFG--LVQPRPPLEPSPTGRHRGVRAVQQQL 1393

Query: 848  VGANRASHRAAAPPR-----------------LLPPLPT--------------CYGPLKV 876
              A    H  AA P                   +PP P                YG + +
Sbjct: 1394 AYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHM 1453

Query: 877  ----GGTN--PSC-------GHPEVGRLGGGPALYPPP-EGQVCNPLDSLDLDNTQLDFV 922
                GG     SC         P+  +    P   P P   QV + +DS  L+  Q+DF 
Sbjct: 1454 YEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFD 1513

Query: 923  AILDEPQ-------GLSPPPSHD-QRGSSGHTPP---------PSGPPNMAVGNMSVLLR 965
            AI+D+          LSP   H   + SS  T P         P+G  NMAVG+MS +L 
Sbjct: 1514 AIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLT 1573

Query: 966  SLPGETEFLN 975
            SL  E++FLN
Sbjct: 1574 SLAEESKFLN 1583


>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
          Length = 1580

 Score =  452 bits (1164), Expect = e-127
 Identities = 337/867 (38%), Positives = 428/867 (49%), Gaps = 189/867 (21%)

Query: 17   PSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLK--------SELDMLVGKCREEPLE 68
            P+P+F  Q   P       + P   S GP  + Q K        S  D +  K  +   +
Sbjct: 383  PAPTFPTQR--PIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPD 440

Query: 69   GDMSSPNSTGIQDPLLGMLDGREDLEREE-KREPESVYETDCRWDGCSQEFDSQEQLVHH 127
             D+ SP + G Q+   G    +E+ +++E K+EPE +YET+C W+GC++EFD+QEQLVHH
Sbjct: 441  EDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHH 500

Query: 128  INSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRL 187
            IN++HIHGE+KEFVC W  CSRE +PFKAQYMLVVHMRRHTGEKPHKCTFEGC K+YSRL
Sbjct: 501  INNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRL 560

Query: 188  ENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTD 247
            ENLKTHLRSHTGEKPY+CEHEGC+KAFSNASDRAKHQNRTHSNEKPYVCK+PGCTKRYTD
Sbjct: 561  ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTD 620

Query: 248  PSSLRKHVKTVHGPDAHVTKRHRGD-GPLPRAPSISTVEPKREREGGPI----------- 295
            PSSLRKHVKTVHGP+AHVTK+ RGD  P P  P  S    +    G P            
Sbjct: 621  PSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLS 680

Query: 296  -----REES---RLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGST 347
                 REE    +    E  M  QPSPG QSSCSS  SP  + +N  SG+E+    GGS 
Sbjct: 681  NTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSI 738

Query: 348  EDLSSLDEGPCI------AGTGLSTLRR--------LENLRLDQLHQ-------LRPI-- 384
             DLS++DE P +      A T L+   R        +E+++L++L Q       L PI  
Sbjct: 739  GDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILP 798

Query: 385  ------------GTRGLKLPSLSHTGTTVSRR---VGPPVS----LERRSSSSSSISSAY 425
                        GT+     SL    T +  R    G  V+    L RR SS+S+ISSAY
Sbjct: 799  PKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSASTISSAY 858

Query: 426  TVSRRSSLASP-------------------------FPPGS----------PPENGASSL 450
              SRRSS  SP                         + P S             +G  SL
Sbjct: 859  LSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSL 918

Query: 451  PGLMPAQHYLLRARYASARGGGTSPTAASSLDRIG--------------GLPMPP----- 491
              L PAQ Y L+A+YA+A  GG  PT   +++R+               G+ +PP     
Sbjct: 919  LSLTPAQQYRLKAKYAAAT-GGPPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPR 977

Query: 492  ---------WRSRAEYPGYNPNAGVTRRASDPAQ-AADRPAPARVQRFKSLGCVHTPPTV 541
                     +  R   P   P  GV RRASDP +  ++  A  RV RF SL   + PP +
Sbjct: 978  RCSDGGAHGYGRRHLQPHDAPGHGV-RRASDPVRTGSEGLALPRVPRFSSLSSCN-PPAM 1035

Query: 542  AGGGQNFDPYLPTSV-----------YSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 590
            A   +     L                SP PPSITEN  +++  +  +  +         
Sbjct: 1036 ATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDE------ 1089

Query: 591  NPYMDFPPTDTLGYGGPEGAAAE----PYGARGPGSLPLGPG-------PPTNYG----- 634
                DF P D + Y   +  A      P        +P GPG       P ++ G     
Sbjct: 1090 ----DFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHA 1145

Query: 635  -PNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALGGTYSQCPRLEHYG---QVQVKPEQ 690
               PCP+ +    P Q  W E  S S      K   G     P+   +G    + V P+ 
Sbjct: 1146 LEQPCPEGSKTDLPIQ--WNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQN 1203

Query: 691  GCPVGSDSTGLAPCL--NAHPSEGPPH 715
              P+ S   G    L  N++P  GP H
Sbjct: 1204 --PLRSGPAGGYQTLGENSNPYGGPEH 1228



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 20/98 (20%)

Query: 897  LYPPPEGQVCNPLDSLD---LDNTQLDFVAILDEPQ-------GLSPPPSHDQRGSSGH- 945
            L  P   QV + +DSLD   L+  Q+DF AI+D+          LSP    +   SS   
Sbjct: 1479 LLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRL 1538

Query: 946  -TPPPSGP--------PNMAVGNMSVLLRSLPGETEFL 974
             TP  S P         NMA+G+MS LL SL  E++FL
Sbjct: 1539 TTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFL 1576


>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
          Length = 930

 Score =  229 bits (585), Expect = 7e-60
 Identities = 104/168 (61%), Positives = 123/168 (73%), Gaps = 2/168 (1%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRH 167
           CRW  CS  +D QE+LV HI   HI   + E F C W GC R  +PF A+Y L++HMR H
Sbjct: 502 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 561

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           +GEKP+KCTFEGC K++SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 562 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 620

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPL 275
           H + KPY C++PGCTKRYTDPSSLRKHVK     +    K+ R    L
Sbjct: 621 HLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTEL 668


>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
          Length = 775

 Score =  229 bits (585), Expect = 7e-60
 Identities = 104/168 (61%), Positives = 123/168 (73%), Gaps = 2/168 (1%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRH 167
           CRW  CS  +D QE+LV HI   HI   + E F C W GC R  +PF A+Y L++HMR H
Sbjct: 347 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 406

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           +GEKP+KCTFEGC K++SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 465

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPL 275
           H + KPY C++PGCTKRYTDPSSLRKHVK     +    K+ R    L
Sbjct: 466 HLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTEL 513


>gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
          Length = 620

 Score =  224 bits (570), Expect = 4e-58
 Identities = 101/165 (61%), Positives = 122/165 (73%), Gaps = 3/165 (1%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRH 167
           CRW  C   ++ QE+LV HI   HI   + E F C W GC R  +PF A+Y L++HMR H
Sbjct: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           +GEKP+KC FEGC K++SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 315

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKR-HRG 271
           H + KPY C++PGC+KRYTDPSSLRKHVK     +  V K+ H G
Sbjct: 316 HLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAG 360


>gi|110431364 GLIS family zinc finger 2 [Homo sapiens]
          Length = 524

 Score =  197 bits (501), Expect = 4e-50
 Identities = 98/200 (49%), Positives = 128/200 (64%), Gaps = 11/200 (5%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRH 167
           CRW  C+Q F+  + LV H+N  H+  E+   + CHW GC+R  R F A+Y +++H+R H
Sbjct: 170 CRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTH 229

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           T EKPH+C    C KS+SRLENLK H RSHTGEKPY+C +EGC+K +SN+SDR KH  RT
Sbjct: 230 TNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKH-TRT 286

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPK 287
           H  +KPY CK+PGC KRYTDPSSLRKH+K  HG   H     + +    R P      P 
Sbjct: 287 HYVDKPYYCKMPGCHKRYTDPSSLRKHIK-AHG---HFVSHEQQELLQLRPP---PKPPL 339

Query: 288 REREGGPIREESRLTVPEGA 307
              +GGP    +++ +P  A
Sbjct: 340 PAPDGGPYVSGAQIIIPNPA 359


>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
          Length = 334

 Score =  178 bits (452), Expect = 2e-44
 Identities = 86/165 (52%), Positives = 111/165 (67%), Gaps = 12/165 (7%)

Query: 106 ETDCRW---DG------CSQEFDSQEQLVHHINSEHIHG-ERKEFVCHWGGCSRELRPFK 155
           E  C+W   DG      CS+ F +  +LV H+  EH+ G E+   +C W  C R+ +PFK
Sbjct: 127 ELICKWLAADGTATPSLCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFK 186

Query: 156 AQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFS 215
           A+Y LV H+R HTGEKP  C F GC K ++R ENLK H R+HTGEKP+ CE EGC + F+
Sbjct: 187 AKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFA 246

Query: 216 NASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           N+SDR KH +  H+++KPY CK+ GC K YT PSSLRKH+K VHG
Sbjct: 247 NSSDRKKH-SHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMK-VHG 289


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score =  177 bits (448), Expect = 6e-44
 Identities = 78/144 (54%), Positives = 103/144 (71%), Gaps = 2/144 (1%)

Query: 114 CSQEFDSQEQLVHHINSEHIHG-ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKP 172
           CS+ F +  +LV+H+  EH+ G E+   VC W  C RE +PFKA+Y L+ H+R HTGEKP
Sbjct: 431 CSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP 490

Query: 173 HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK 232
             C F GC K ++R ENLK H R+HTGEKP+ CE +GC + F+N+SDR KH +  H+++K
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKH-SHVHTSDK 549

Query: 233 PYVCKLPGCTKRYTDPSSLRKHVK 256
           PY CK+ GC K YT PSSLRKH+K
Sbjct: 550 PYYCKIRGCDKSYTHPSSLRKHMK 573



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 10/128 (7%)

Query: 109 CRWDGCSQE---FDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMR 165
           C W+ C +E   F ++ +L++HI    +H   K F C + GC    + F     L +H R
Sbjct: 460 CFWEDCPREGKPFKAKYKLINHIR---VHTGEKPFPCPFPGCG---KVFARSENLKIHKR 513

Query: 166 RHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQN 225
            HTGEKP KC F+GC + ++   + K H   HT +KPY C+  GC K++++ S   KH  
Sbjct: 514 THTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHM- 572

Query: 226 RTHSNEKP 233
           + H    P
Sbjct: 573 KIHCKSPP 580



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 180 CRKSYSRLENLKTHLR-SHTG---EKPYMCEHEGCSKAFSNASDRAKHQN--RTHSNEKP 233
           C K++  +  L  H+   H G   +  ++C  E C +       + K  N  R H+ EKP
Sbjct: 431 CSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP 490

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           + C  PGC K +    +L+ H +T  G
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRTHTG 517



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 83/363 (22%), Positives = 108/363 (29%), Gaps = 80/363 (22%)

Query: 609 GAAAEPYGARGPGSLPLGPGPPT-NYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKA 667
           GA + P G    G+ P  P PP     P P P     P P     G   ++SG   G   
Sbjct: 132 GAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSG-GGGSSG 190

Query: 668 LGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPS 727
            G +     R +           G P+G +            +  P HP P     P  S
Sbjct: 191 KGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRS--------GTGSPQHPAP-----PPHS 237

Query: 728 PPQYLQ-SGPYTQPP----PDYLPS-EPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELL 781
              ++  SG Y  P     P   P+    P      P    GQ++  L      +  EL 
Sbjct: 238 AGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELY 297

Query: 782 WEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPG---FGPNLPNHKSGSYPT 838
               GR + P    S       G +      A A    +G G      NL    + +   
Sbjct: 298 ----GRAEPPFAPRS-------GDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAG 346

Query: 839 PSPCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALY 898
           P P             H A  P    PP P           +P   HP +    G    Y
Sbjct: 347 PGP----------HLQHHAPPPAPPPPPAP---------AQHPHQHHPHLPGAAGAFLRY 387

Query: 899 ---PPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNM 955
              P  +  +C  +D               DE  GL PPP           PPP  PP  
Sbjct: 388 MRQPIKQELICKWIDP--------------DELAGLPPPPP---------PPPPPPPPPP 424

Query: 956 AVG 958
           A G
Sbjct: 425 AGG 427



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 64/270 (23%), Positives = 83/270 (30%), Gaps = 47/270 (17%)

Query: 567 NAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTDTLG-YGGPEGAAAEPYGARGPGSLPL 625
           +A   A  +   P  G    G+G +P    PP  + G +    G  A P G+ GP   P 
Sbjct: 204 SATAPAAAMHGAPLGGEQRSGTG-SPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPA 262

Query: 626 ---GPGPPTNYGPNPCPQQ------ASYPDPTQETWGEFPSHSGLYPGPKALGGTYSQCP 676
               PG P  + P+P   Q      A+      E +G          G    G   +   
Sbjct: 263 LHDTPGAPGGH-PHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAA 321

Query: 677 RLEH-YGQVQVKPEQGCPVGSDSTGLAPCLNAH--PSEGPPHPQPL---FSHYP------ 724
              H YG V +         + + G  P L  H  P   PP P P      H+P      
Sbjct: 322 AALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAA 381

Query: 725 --------QP---------SPPQYLQSGPYTQPPPDYLPSEP-----RPCLDFDSPTHS- 761
                   QP           P  L   P   PPP   P  P     +PC       H  
Sbjct: 382 GAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHEL 441

Query: 762 TGQLKAQLVCNYVQSQQELLWEGGGREDAP 791
              +  + V    QS     WE   RE  P
Sbjct: 442 VNHVTVEHVGGPEQSSHVCFWEDCPREGKP 471


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score =  176 bits (446), Expect = 1e-43
 Identities = 100/252 (39%), Positives = 138/252 (54%), Gaps = 24/252 (9%)

Query: 106 ETDCRW----------DGCSQEFDSQEQLVHHINSEHIHG-ERKEFVCHWGGCSRELRPF 154
           E  C+W            C++ F +  +LV H++ EH+ G E+   VC W  C RE +PF
Sbjct: 255 ELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPF 314

Query: 155 KAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAF 214
           KA+Y LV H+R HTGEKP  C F GC K ++R ENLK H R+HTGEKP+ CE EGC + F
Sbjct: 315 KAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRF 374

Query: 215 SNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGP 274
           +N+SDR KH +  H+++KPY+CK+  C K YT PSSLRKH+K VH      ++      P
Sbjct: 375 ANSSDRKKHMH-VHTSDKPYLCKM--CDKSYTHPSSLRKHMK-VHESSPQGSE----SSP 426

Query: 275 LPRAPSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTD 334
              +   S+  P         +  S L+ P  A     +  A ++ S+ H   GS +   
Sbjct: 427 AASSGYESSTPPGLVSPSAEPQSSSNLS-PAAAAAAAAAAAAAAAVSAVHRGGGSGSGGA 485

Query: 335 SGVEMTGNAGGS 346
            G    G+ GGS
Sbjct: 486 GG----GSGGGS 493


>gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]
          Length = 447

 Score =  172 bits (435), Expect = 2e-42
 Identities = 87/186 (46%), Positives = 115/186 (61%), Gaps = 21/186 (11%)

Query: 106 ETDCRW----------DGCSQEFDSQEQLVHHINSEHIHG-ERKEFVCHWGGCSRELRPF 154
           E  C+W            C++ F +  +LV H+  EH+ G E+   +C W  C RE +PF
Sbjct: 224 ELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPF 283

Query: 155 KAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAF 214
           KA+Y LV H+R HTGEKP  C F GC K ++R ENLK H R+HTGEKP+ CE EGC + F
Sbjct: 284 KAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRF 343

Query: 215 SNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGP 274
           +N+SDR KH +  H+++KPY+CK+  C K YT PSSLRKH+K VH   +      +G  P
Sbjct: 344 ANSSDRKKHMH-VHTSDKPYLCKM--CDKSYTHPSSLRKHMK-VHESSS------QGSQP 393

Query: 275 LPRAPS 280
            P A S
Sbjct: 394 SPAASS 399


>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
          Length = 467

 Score =  171 bits (433), Expect = 3e-42
 Identities = 99/260 (38%), Positives = 137/260 (52%), Gaps = 30/260 (11%)

Query: 19  PSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSEL-DMLVGKCRE-EPLEGDMSSPNS 76
           PS+ + P G H+   G    HP   G     Q+   L   L G+     P+    + P +
Sbjct: 157 PSYLLFP-GLHEQGAG----HPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYA 211

Query: 77  TGIQDPLLGMLDGREDLEREEKREPESVY---------ETDCRW----------DGCSQE 117
            G Q P    ++    +       P + +         E  C+W            C + 
Sbjct: 212 AGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCDRT 271

Query: 118 FDSQEQLVHHINSEHIHG-ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCT 176
           F +  +LV H+  EH+ G E+   VC+W  C RE + FKA+Y LV H+R HTGEKP  C 
Sbjct: 272 FSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCP 331

Query: 177 FEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVC 236
           F GC K ++R ENLK H R+HTGEKP+ CE EGC + F+N+SDR KH +  H+++KPY+C
Sbjct: 332 FPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMH-VHTSDKPYIC 390

Query: 237 KLPGCTKRYTDPSSLRKHVK 256
           K+  C K YT PSSLRKH+K
Sbjct: 391 KV--CDKSYTHPSSLRKHMK 408



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 43/177 (24%), Positives = 74/177 (41%), Gaps = 25/177 (14%)

Query: 178 EGCRKSYSRLENLKTHLR-SHTG---EKPYMCEHEGCSKAFSNASDRAKHQN--RTHSNE 231
           + C +++S +  L TH+   H G   +  ++C  E C +   +   + K  N  R H+ E
Sbjct: 266 KSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGE 325

Query: 232 KPYVCKLPGCTKRYTDPSSLRKHVKTVHG---------------PDAHVTKRHRGDGPLP 276
           KP+ C  PGC K +    +L+ H +T  G                ++   K+H       
Sbjct: 326 KPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSD 385

Query: 277 RAPSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANT 333
           + P I  V  K       +R+  ++   +G+     SP A S   S   PA ++AN+
Sbjct: 386 K-PYICKVCDKSYTHPSSLRKHMKVHESQGS---DSSPAASSGYESSTPPAIASANS 438


>gi|116014328 zinc finger protein 143 [Homo sapiens]
          Length = 638

 Score =  129 bits (324), Expect = 1e-29
 Identities = 74/207 (35%), Positives = 105/207 (50%), Gaps = 14/207 (6%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHT 168
           C   GC + F +   L  H+ +   H   K + C    C++    FK    L  H+R HT
Sbjct: 269 CEHAGCGKAFATGYGLKSHVRT---HTGEKPYRCSEDNCTKS---FKTSGDLQKHIRTHT 322

Query: 169 GEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTH 228
           GE+P KC FEGC +S++     K H+R+HTGE+PY C   GC +AF++A++   H  R H
Sbjct: 323 GERPFKCPFEGCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHV-RIH 381

Query: 229 SNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKR 288
           + EKPYVC +PGC KR+T+ SSL KH   VH         H G     +  +++  +   
Sbjct: 382 TGEKPYVCTVPGCDKRFTEYSSLYKH-HVVHTHSKPYNCNHCGK-TYKQISTLAMHKRTA 439

Query: 289 EREGGPIREESRLTVPEGAMKPQPSPG 315
             +  PI EE      E   +P P  G
Sbjct: 440 HNDTEPIEEEQ-----EAFFEPPPGQG 461



 Score =  108 bits (269), Expect = 3e-23
 Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 4/123 (3%)

Query: 138 KEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSH 197
           K F C + GC +    +   + L VH R HTG++P++C   GC K+++    LK+H+R+H
Sbjct: 235 KAFRCEYDGCGKL---YTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRTH 291

Query: 198 TGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKT 257
           TGEKPY C  + C+K+F  + D  KH  RTH+ E+P+ C   GC + +T  +  + HV+T
Sbjct: 292 TGEKPYRCSEDNCTKSFKTSGDLQKH-IRTHTGERPFKCPFEGCGRSFTTSNIRKVHVRT 350

Query: 258 VHG 260
             G
Sbjct: 351 HTG 353



 Score =  100 bits (248), Expect = 9e-21
 Identities = 49/112 (43%), Positives = 63/112 (56%), Gaps = 7/112 (6%)

Query: 155 KAQYMLVVHMRRHT------GEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHE 208
           K Q +L  H  R T      GEK  +C ++GC K Y+   +LK H RSHTG++PY CEH 
Sbjct: 213 KMQIVLQGHATRVTAKSQQSGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHA 272

Query: 209 GCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           GC KAF+       H  RTH+ EKPY C    CTK +     L+KH++T  G
Sbjct: 273 GCGKAFATGYGLKSHV-RTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTG 323


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score =  120 bits (301), Expect = 6e-27
 Identities = 61/162 (37%), Positives = 87/162 (53%), Gaps = 8/162 (4%)

Query: 95  REEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPF 154
           R  ++     Y   C  +GC + F +   L  H+    +H + K F C   GC +    F
Sbjct: 158 RTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVR---VHTKEKPFECDVQGCEKA---F 211

Query: 155 KAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAF 214
              Y L  H R HTG K   C  EGC K ++ L +L+ H+R+HTGEKP+ C+H+GC KAF
Sbjct: 212 NTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAF 270

Query: 215 SNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVK 256
           + AS   K   RTH+ E+P+ C   GC K ++   SL+ H+K
Sbjct: 271 A-ASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMK 311



 Score =  117 bits (292), Expect = 7e-26
 Identities = 65/165 (39%), Positives = 89/165 (53%), Gaps = 10/165 (6%)

Query: 96  EEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFK 155
           E KR+    Y+  C ++GC + + +   L  H   +  H     FVC+  GC +    F 
Sbjct: 131 ETKRKEVKRYQ--CTFEGCPRTYSTAGNLRTH---QKTHRGEYTFVCNQEGCGKA---FL 182

Query: 156 AQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFS 215
             Y L +H+R HT EKP +C  +GC K+++ L  LK H R HTG K + CE EGCSK F+
Sbjct: 183 TSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFT 241

Query: 216 NASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
             SD  KH  RTH+ EKP+ C   GC K +     L+ HV+T  G
Sbjct: 242 TLSDLRKHI-RTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTG 285



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 48/126 (38%), Positives = 68/126 (53%), Gaps = 11/126 (8%)

Query: 108 DCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRH 167
           +C   GC + F++  +L  H   + +H   K F C   GCS+    F     L  H+R H
Sbjct: 201 ECDVQGCEKAFNTLYRLKAH---QRLH-TGKTFNCESEGCSKY---FTTLSDLRKHIRTH 253

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSN----ASDRAKH 223
           TGEKP +C  +GC K+++   +LKTH+R+HTGE+P+ C   GC K FS      S    H
Sbjct: 254 TGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGH 313

Query: 224 QNRTHS 229
            N+ HS
Sbjct: 314 DNKGHS 319


>gi|21361146 zinc finger protein 76 (expressed in testis) [Homo
           sapiens]
          Length = 570

 Score =  118 bits (296), Expect = 2e-26
 Identities = 59/146 (40%), Positives = 84/146 (57%), Gaps = 7/146 (4%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHT 168
           C +  C + F +   L  H+ +   H   K + C    CS+    FK    L  H+R HT
Sbjct: 197 CDFPSCGKAFATGYGLKSHVRT---HTGEKPYKCPEELCSKA---FKTSGDLQKHVRTHT 250

Query: 169 GEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTH 228
           GE+P +C FEGC +S++     K H+R+HTGE+PY C    C + F++A++   H  R H
Sbjct: 251 GERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHV-RIH 309

Query: 229 SNEKPYVCKLPGCTKRYTDPSSLRKH 254
           + EKPYVC +PGC KR+T+ SSL KH
Sbjct: 310 TGEKPYVCTVPGCGKRFTEYSSLYKH 335



 Score =  112 bits (279), Expect = 2e-24
 Identities = 54/157 (34%), Positives = 86/157 (54%), Gaps = 7/157 (4%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHT 168
           C + GC + + +   L  H   E  H   + + C +  C +    F   Y L  H+R HT
Sbjct: 167 CGYKGCGRLYTTAHHLKVH---ERAHTGDRPYRCDFPSCGKA---FATGYGLKSHVRTHT 220

Query: 169 GEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTH 228
           GEKP+KC  E C K++    +L+ H+R+HTGE+P+ C  EGC ++F+ ++ R  H  RTH
Sbjct: 221 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHV-RTH 279

Query: 229 SNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHV 265
           + E+PY C  P C + +T  ++ + HV+   G   +V
Sbjct: 280 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYV 316



 Score =  109 bits (273), Expect = 1e-23
 Identities = 51/123 (41%), Positives = 74/123 (60%), Gaps = 4/123 (3%)

Query: 138 KEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSH 197
           + F C + GC R    +   + L VH R HTG++P++C F  C K+++    LK+H+R+H
Sbjct: 163 RAFRCGYKGCGRL---YTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTH 219

Query: 198 TGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKT 257
           TGEKPY C  E CSKAF  + D  KH  RTH+ E+P+ C   GC + +T  +  + HV+T
Sbjct: 220 TGEKPYKCPEELCSKAFKTSGDLQKHV-RTHTGERPFQCPFEGCGRSFTTSNIRKVHVRT 278

Query: 258 VHG 260
             G
Sbjct: 279 HTG 281



 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 36/95 (37%), Positives = 55/95 (57%), Gaps = 1/95 (1%)

Query: 166 RHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQN 225
           +  G++  +C ++GC + Y+   +LK H R+HTG++PY C+   C KAF+       H  
Sbjct: 158 QQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHV- 216

Query: 226 RTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           RTH+ EKPY C    C+K +     L+KHV+T  G
Sbjct: 217 RTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTG 251



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 62/260 (23%), Positives = 100/260 (38%), Gaps = 29/260 (11%)

Query: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHT 168
           C ++GC + F +      H+ +   H   + + C    C R    F +      H+R HT
Sbjct: 257 CPFEGCGRSFTTSNIRKVHVRT---HTGERPYTCPEPHCGRG---FTSATNYKNHVRIHT 310

Query: 169 GEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTH 228
           GEKP+ CT  GC K ++   +L  H   HT  KPY C    C K +   S  A H+   H
Sbjct: 311 GEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTC--STCGKTYRQTSTLAMHKRSAH 368

Query: 229 SNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTV-EPK 287
              +         T+        ++ ++     +         + P P+ P I+ + E K
Sbjct: 369 GELE--------ATEESEQALYEQQQLEAASAAE---------ESPPPKRPRIAYLSEVK 411

Query: 288 REREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGST 347
            ER+  P  + + +T  +GA  PQ +   Q                 S + M    G +T
Sbjct: 412 EERDDIP-AQVAMVTEEDGA--PQVALITQDGAQQVSLSPEDLQALGSAISMVTQHGSTT 468

Query: 348 EDLSSLDEGPCIAGTGLSTL 367
             + S D     +GT   T+
Sbjct: 469 LTIPSPDADLATSGTHTVTM 488


>gi|10863995 zinc finger protein 410 [Homo sapiens]
          Length = 478

 Score =  115 bits (289), Expect = 2e-25
 Identities = 92/305 (30%), Positives = 135/305 (44%), Gaps = 44/305 (14%)

Query: 56  DMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCS 115
           D L+   R +  +   +S N   +    LG  DG+    ++    P+   +  C  +GC 
Sbjct: 174 DSLIAATRAQLAKNAKTSSNGENVH---LGSGDGQS---KDSGPLPQVEKKLKCTVEGCD 227

Query: 116 QEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKC 175
           + F       +H+ +   H   + F+C   GC +    F     L VHMR H GEKP  C
Sbjct: 228 RTFVWPAHFKYHLKT---HRNDRSFICPAEGCGKS---FYVLQRLKVHMRTHNGEKPFMC 281

Query: 176 TFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYV 235
              GC K ++   NLK H R HTGEKP++CE +GC ++F+  S   KH    HS EKP+ 
Sbjct: 282 HESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHL-VVHSGEKPHQ 340

Query: 236 CKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPI 295
           C++  C K ++   S           + H+ K H   G         T EP     G  +
Sbjct: 341 CQV--CGKTFSQSGS----------RNVHMRKHHLQLGAAGSQEQEQTAEPLM---GSSL 385

Query: 296 REESRLTVPEG---AMKPQPSPGAQSSCSSDHSPAGSAANTDS--GVEMTGNAGGSTEDL 350
            EE+  +VP     +M  QPS G +S          +  NT+S  GV+    A GS   L
Sbjct: 386 LEEA--SVPSKNLVSMNSQPSLGGESL---------NLPNTNSILGVDDEVLAEGSPRSL 434

Query: 351 SSLDE 355
           SS+ +
Sbjct: 435 SSVPD 439


>gi|28376656 zinc finger, X-linked, duplicated B [Homo sapiens]
          Length = 803

 Score =  110 bits (276), Expect = 5e-24
 Identities = 67/214 (31%), Positives = 106/214 (49%), Gaps = 32/214 (14%)

Query: 100 EPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYM 159
           EPE  Y+  C + GC + F +   L  H N  H   E++ F C + GCS++   +     
Sbjct: 388 EPERPYQ--CAFSGCKKTFITVSALFSH-NRAHFR-EQELFSCSFPGCSKQ---YDKACR 440

Query: 160 LVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 219
           L +H+R HTGE+P  C F+GC  +++ +  L  H R H  ++ +MC  EGC K+F+ A +
Sbjct: 441 LKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRA-E 499

Query: 220 RAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSL----RKHVKTV----------------- 258
             K  + TH   KP+VC + GC  R++  SSL    +KH++ V                 
Sbjct: 500 HLKGHSITHLGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKSRCPISSCNKLFT 559

Query: 259 --HGPDAHVTKRHR-GDGPLPRAPSISTVEPKRE 289
             H    H+ KRH+ G   L +  + +++ P  E
Sbjct: 560 SKHSMKTHMVKRHKVGQDLLAQLEAANSLTPSSE 593



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 45/141 (31%), Positives = 66/141 (46%), Gaps = 5/141 (3%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C Q F  + QL  H+ +      ++ F C  GGC      F   Y L  H++ H   +P 
Sbjct: 278 CGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWT---FTTSYKLKRHLQSHDKLRPF 334

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
            C  EGC KS++ + NLK H++ H  E  + CE   C ++F   +  + HQ      E+P
Sbjct: 335 GCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEV--CEESFPTQAKLSAHQRSHFEPERP 392

Query: 234 YVCKLPGCTKRYTDPSSLRKH 254
           Y C   GC K +   S+L  H
Sbjct: 393 YQCAFSGCKKTFITVSALFSH 413



 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 34/126 (26%), Positives = 62/126 (49%), Gaps = 9/126 (7%)

Query: 140 FVCHWGGCSRELRPFKAQYMLVVHMRRHT---GEKPHKCTFEGCRKSYSRLENLKTHLRS 196
           ++C    C +    F  ++ L VH+  H+   G++P KC   GC  +++    LK HL+S
Sbjct: 271 YLCPEAQCGQT---FAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQS 327

Query: 197 HTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVK 256
           H   +P+ C  EGC K+F+   +   H  + H  E  + C++  C + +   + L  H +
Sbjct: 328 HDKLRPFGCPAEGCGKSFTTVYNLKAHM-KGHEQENSFKCEV--CEESFPTQAKLSAHQR 384

Query: 257 TVHGPD 262
           +   P+
Sbjct: 385 SHFEPE 390


>gi|28274709 zinc finger, X-linked, duplicated A [Homo sapiens]
          Length = 799

 Score =  110 bits (276), Expect = 5e-24
 Identities = 67/214 (31%), Positives = 106/214 (49%), Gaps = 32/214 (14%)

Query: 100 EPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYM 159
           EPE  Y+  C + GC + F +   L  H N  H   E++ F C + GCS++   +     
Sbjct: 384 EPERPYQ--CAFSGCKKTFITVSALFSH-NRAHFR-EQELFSCSFPGCSKQ---YDKACR 436

Query: 160 LVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 219
           L +H+R HTGE+P  C F+GC  +++ +  L  H R H  ++ +MC  EGC K+F+ A +
Sbjct: 437 LKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRA-E 495

Query: 220 RAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSL----RKHVKTV----------------- 258
             K  + TH   KP+VC + GC  R++  SSL    +KH++ V                 
Sbjct: 496 HLKGHSITHLGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKSRCPISSCNKLFT 555

Query: 259 --HGPDAHVTKRHR-GDGPLPRAPSISTVEPKRE 289
             H    H+ KRH+ G   L +  + +++ P  E
Sbjct: 556 SKHSMKTHMVKRHKVGQDLLAQLEAANSLTPSSE 589



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 45/141 (31%), Positives = 65/141 (46%), Gaps = 5/141 (3%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C Q F  + QL  H+ +      ++ F C  GGC      F   Y L  H++ H   +P 
Sbjct: 274 CGQTFAKKHQLKMHLLTHSSSQGQRPFKCPLGGCGWT---FTTSYKLKRHLQSHDKLRPF 330

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
            C  EGC KS++ + NLK H++ H  E  + CE   C ++F   +    HQ      E+P
Sbjct: 331 GCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEV--CEESFPTQAKLGAHQRSHFEPERP 388

Query: 234 YVCKLPGCTKRYTDPSSLRKH 254
           Y C   GC K +   S+L  H
Sbjct: 389 YQCAFSGCKKTFITVSALFSH 409



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 6/112 (5%)

Query: 154 FKAQYMLVVHMRRHT---GEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGC 210
           F  ++ L +H+  H+   G++P KC   GC  +++    LK HL+SH   +P+ C  EGC
Sbjct: 278 FAKKHQLKMHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGC 337

Query: 211 SKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPD 262
            K+F+   +   H  + H  E  + C++  C + +   + L  H ++   P+
Sbjct: 338 GKSFTTVYNLKAHM-KGHEQENSFKCEV--CEESFPTQAKLGAHQRSHFEPE 386


>gi|65507817 Wilms tumor 1 isoform B [Homo sapiens]
          Length = 514

 Score =  106 bits (265), Expect = 9e-23
 Identities = 50/119 (42%), Positives = 74/119 (62%), Gaps = 6/119 (5%)

Query: 136 ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 195
           E++ F+C + GC++  R FK  + L +H R+HTGEKP++C F+ C + +SR + LK H R
Sbjct: 387 EKRPFMCAYPGCNK--RYFKLSH-LQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQR 443

Query: 196 SHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 254
            HTG KP+ C  + C + FS  SD  K   RTH+ EKP+ C+ P C K++     L +H
Sbjct: 444 RHTGVKPFQC--KTCQRKFSR-SDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRH 499



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 17/155 (10%)

Query: 85  GMLDGREDLEREEKREP---ESVYETD------CRWDGCSQEFDSQEQLVHHINSEHIHG 135
           G+  G +D+ R     P    S  ET       C + GC++ +     L  H      H 
Sbjct: 360 GVFRGIQDVRRVPGVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRK---HT 416

Query: 136 ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 195
             K + C +  C R    F     L  H RRHTG KP +C  + C++ +SR ++LKTH R
Sbjct: 417 GEKPYQCDFKDCERR---FSRSDQLKRHQRRHTGVKPFQC--KTCQRKFSRSDHLKTHTR 471

Query: 196 SHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSN 230
           +HTGEKP+ C    C K F+ + +  +H N    N
Sbjct: 472 THTGEKPFSCRWPSCQKKFARSDELVRHHNMHQRN 506



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 39/101 (38%), Positives = 56/101 (55%), Gaps = 4/101 (3%)

Query: 161 VVHMRRHTGEK-PHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 219
           +V     T EK P  C + GC K Y +L +L+ H R HTGEKPY C+ + C + FS  SD
Sbjct: 378 LVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSR-SD 436

Query: 220 RAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           + K   R H+  KP+ CK   C ++++    L+ H +T  G
Sbjct: 437 QLKRHQRRHTGVKPFQCKT--CQRKFSRSDHLKTHTRTHTG 475


>gi|65507714 Wilms tumor 1 isoform A [Homo sapiens]
          Length = 497

 Score =  106 bits (265), Expect = 9e-23
 Identities = 50/119 (42%), Positives = 74/119 (62%), Gaps = 6/119 (5%)

Query: 136 ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 195
           E++ F+C + GC++  R FK  + L +H R+HTGEKP++C F+ C + +SR + LK H R
Sbjct: 370 EKRPFMCAYPGCNK--RYFKLSH-LQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQR 426

Query: 196 SHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 254
            HTG KP+ C  + C + FS  SD  K   RTH+ EKP+ C+ P C K++     L +H
Sbjct: 427 RHTGVKPFQC--KTCQRKFSR-SDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRH 482



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 17/155 (10%)

Query: 85  GMLDGREDLEREEKREP---ESVYETD------CRWDGCSQEFDSQEQLVHHINSEHIHG 135
           G+  G +D+ R     P    S  ET       C + GC++ +     L  H      H 
Sbjct: 343 GVFRGIQDVRRVPGVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRK---HT 399

Query: 136 ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 195
             K + C +  C R    F     L  H RRHTG KP +C  + C++ +SR ++LKTH R
Sbjct: 400 GEKPYQCDFKDCERR---FSRSDQLKRHQRRHTGVKPFQC--KTCQRKFSRSDHLKTHTR 454

Query: 196 SHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSN 230
           +HTGEKP+ C    C K F+ + +  +H N    N
Sbjct: 455 THTGEKPFSCRWPSCQKKFARSDELVRHHNMHQRN 489



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 39/101 (38%), Positives = 56/101 (55%), Gaps = 4/101 (3%)

Query: 161 VVHMRRHTGEK-PHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 219
           +V     T EK P  C + GC K Y +L +L+ H R HTGEKPY C+ + C + FS  SD
Sbjct: 361 LVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSR-SD 419

Query: 220 RAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           + K   R H+  KP+ CK   C ++++    L+ H +T  G
Sbjct: 420 QLKRHQRRHTGVKPFQCKT--CQRKFSRSDHLKTHTRTHTG 458


>gi|48717244 zinc finger protein 782 [Homo sapiens]
          Length = 699

 Score =  105 bits (262), Expect = 2e-22
 Identities = 66/178 (37%), Positives = 89/178 (50%), Gaps = 16/178 (8%)

Query: 95  REEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPF 154
           R  K +     E   + DGC + F ++  L  H   +  H   K F CH  G S     F
Sbjct: 408 RLRKHQRTHTGEKPYKCDGCDKAFSAKSGLRIH---QRTHTGEKPFECHECGKS-----F 459

Query: 155 KAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAF 214
             + +L+VH R HTGEKP +C    C KS+S +  L+ H R+HTGE+PY C+   C KAF
Sbjct: 460 NYKSILIVHQRTHTGEKPFECN--ECGKSFSHMSGLRNHRRTHTGERPYKCDE--CGKAF 515

Query: 215 SNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGD 272
              S   KH +RTH+ EKPY C    C K +   S LR H + +H  +      H G+
Sbjct: 516 KLKSGLRKH-HRTHTGEKPYKCN--QCGKAFGQKSQLRGHHR-IHTGEKPYKCNHCGE 569



 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 60/155 (38%), Positives = 80/155 (51%), Gaps = 15/155 (9%)

Query: 106 ETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMR 165
           E   + D C + F  +  L  H      H   K + C+  G     + F  +  L  H R
Sbjct: 503 ERPYKCDECGKAFKLKSGLRKH---HRTHTGEKPYKCNQCG-----KAFGQKSQLRGHHR 554

Query: 166 RHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQN 225
            HTGEKP+KC    C +++S+  NL+ H R+HTGEKPY CE   C K F   S+   HQ 
Sbjct: 555 IHTGEKPYKCNH--CGEAFSQKSNLRVHHRTHTGEKPYQCEE--CGKTFRQKSNLRGHQ- 609

Query: 226 RTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           RTH+ EKPY C    C K +++ S LRKH +T  G
Sbjct: 610 RTHTGEKPYECN--ECGKAFSEKSVLRKHQRTHTG 642



 Score = 93.6 bits (231), Expect = 8e-19
 Identities = 58/148 (39%), Positives = 77/148 (52%), Gaps = 17/148 (11%)

Query: 114 CSQEFDSQEQL-VHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKP 172
           C + F  +  L VHH      H   K + C   G     + F+ +  L  H R HTGEKP
Sbjct: 567 CGEAFSQKSNLRVHH----RTHTGEKPYQCEECG-----KTFRQKSNLRGHQRTHTGEKP 617

Query: 173 HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK 232
           ++C    C K++S    L+ H R+HTGEKPY C    C +AFS  S+   HQ RTH+ EK
Sbjct: 618 YECN--ECGKAFSEKSVLRKHQRTHTGEKPYNCNQ--CGEAFSQKSNLRVHQ-RTHTGEK 672

Query: 233 PYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           PY C    C + ++  SSLR+H K   G
Sbjct: 673 PYKC--DKCGRTFSQKSSLREHQKAHPG 698



 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 54/147 (36%), Positives = 71/147 (48%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C++ F  Q     H    HI  +  E+      CS           L+   + HTGEKP+
Sbjct: 343 CTETFSYQSTFSVH-QKVHIRAKPYEYNECGKSCSMNSH-------LIWPQKSHTGEKPY 394

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           +C    C K++S    L+ H R+HTGEKPY C  +GC KAFS  S    HQ RTH+ EKP
Sbjct: 395 ECP--ECGKAFSEKSRLRKHQRTHTGEKPYKC--DGCDKAFSAKSGLRIHQ-RTHTGEKP 449

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           + C    C K +   S L  H +T  G
Sbjct: 450 FECH--ECGKSFNYKSILIVHQRTHTG 474



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 31/129 (24%), Positives = 49/129 (37%), Gaps = 52/129 (40%)

Query: 182 KSYSRLENLKTHLRSHTGEKPY-----------------------MCEHEGCSKAFSNAS 218
           KS+S+  +++ H R H G KP+                         ++  C++ FS  S
Sbjct: 292 KSFSQKSHIREHHRVHIGVKPFEYGKSFNRNSTLPVHQRTHATDKYSDYHPCTETFSYQS 351

Query: 219 DRAKHQ---------------------------NRTHSNEKPYVCKLPGCTKRYTDPSSL 251
             + HQ                            ++H+ EKPY C  P C K +++ S L
Sbjct: 352 TFSVHQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYEC--PECGKAFSEKSRL 409

Query: 252 RKHVKTVHG 260
           RKH +T  G
Sbjct: 410 RKHQRTHTG 418


>gi|197313746 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  103 bits (258), Expect = 6e-22
 Identities = 58/141 (41%), Positives = 74/141 (52%), Gaps = 15/141 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L+HH   + IH   K ++C   G S     F+    L  H R HTGEKPH
Sbjct: 272 CGKAFNQNTHLIHH---QRIHTGEKPYICSECGSS-----FRKHSNLTQHQRIHTGEKPH 323

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K++    NL  H R H+GEKPY C+   C KAF  +    KHQ R H+ EKP
Sbjct: 324 KC--DECGKTFQTKANLSQHQRIHSGEKPYKCKE--CGKAFCQSPSLIKHQ-RIHTGEKP 378

Query: 234 YVCKLPGCTKRYTDPSSLRKH 254
           Y CK   C K +T  + L KH
Sbjct: 379 YKCK--ECGKAFTQSTPLTKH 397



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 54/151 (35%), Positives = 71/151 (47%), Gaps = 15/151 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     LV H   + IH   K +     GC +  + F+ +  L  H R HTGEKP+
Sbjct: 188 CGKAFSRSSFLVQH---QRIHTGVKPY-----GCEQCGKTFRCRSFLTQHQRIHTGEKPY 239

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C  S+    +L  H R HTGEKPY C    C KAF N +    H  R H+ EKP
Sbjct: 240 KC--NECGNSFRNHSHLTEHQRIHTGEKPYKCNR--CGKAF-NQNTHLIHHQRIHTGEKP 294

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAH 264
           Y+C    C   +   S+L +H +   G   H
Sbjct: 295 YICS--ECGSSFRKHSNLTQHQRIHTGEKPH 323



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 54/147 (36%), Positives = 72/147 (48%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H   + IH   K + C   G     + F     L  H R HTGE+P+
Sbjct: 356 CGKAFCQSPSLIKH---QRIHTGEKPYKCKECG-----KAFTQSTPLTKHQRIHTGERPY 407

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC+   C K++ +   L  H RSHTGEKPY C    C K F+  +   +H  R H+ EKP
Sbjct: 408 KCS--ECGKAFIQSICLIRHQRSHTGEKPYKCNE--CGKGFNQNTCLTQHM-RIHTGEKP 462

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y CK   C K +   SSL +H +T  G
Sbjct: 463 YKCK--ECGKAFAHSSSLTEHHRTHTG 487



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 50/143 (34%), Positives = 72/143 (50%), Gaps = 15/143 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L  H   + IH   + + C   G     + F     L+ H R HTGEKP+
Sbjct: 384 CGKAFTQSTPLTKH---QRIHTGERPYKCSECG-----KAFIQSICLIRHQRSHTGEKPY 435

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K +++   L  H+R HTGEKPY C+   C KAF+++S   +H +RTH+ EK 
Sbjct: 436 KCN--ECGKGFNQNTCLTQHMRIHTGEKPYKCKE--CGKAFAHSSSLTEH-HRTHTGEKL 490

Query: 234 YVCKLPGCTKRYTDPSSLRKHVK 256
           Y C    C K +   + L +H +
Sbjct: 491 YKCS--ECEKTFRKYAHLSEHYR 511



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 52/154 (33%), Positives = 76/154 (49%), Gaps = 15/154 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F  +  L  H   + IH   K + C+  G S     F+    L  H R HTGEKP+
Sbjct: 216 CGKTFRCRSFLTQH---QRIHTGEKPYKCNECGNS-----FRNHSHLTEHQRIHTGEKPY 267

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K++++  +L  H R HTGEKPY+C    C  +F   S+  +HQ R H+ EKP
Sbjct: 268 KCN--RCGKAFNQNTHLIHHQRIHTGEKPYICSE--CGSSFRKHSNLTQHQ-RIHTGEKP 322

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTK 267
           + C    C K +   ++L +H +   G   +  K
Sbjct: 323 HKC--DECGKTFQTKANLSQHQRIHSGEKPYKCK 354



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H  S   H   K + C+  G     + F     L  HMR HTGEKP+
Sbjct: 412 CGKAFIQSICLIRHQRS---HTGEKPYKCNECG-----KGFNQNTCLTQHMRIHTGEKPY 463

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K+++   +L  H R+HTGEK Y C    C K F   +  ++H  R H+ EKP
Sbjct: 464 KC--KECGKAFAHSSSLTEHHRTHTGEKLYKCSE--CEKTFRKYAHLSEHY-RIHTGEKP 518

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y C    C K +   S L +H K   G
Sbjct: 519 YEC--IECGKFFRHSSVLFRHQKLHSG 543



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 46/122 (37%), Positives = 59/122 (48%), Gaps = 7/122 (5%)

Query: 147 CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE 206
           C+   + F     L  H R HTGE+P+ C  E C K++SR   L  H R HTG KPY CE
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTC--EECGKAFSRSSFLVQHQRIHTGVKPYGCE 214

Query: 207 HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVT 266
              C K F   S   +HQ R H+ EKPY C    C   + + S L +H +   G   +  
Sbjct: 215 Q--CGKTFRCRSFLTQHQ-RIHTGEKPYKCN--ECGNSFRNHSHLTEHQRIHTGEKPYKC 269

Query: 267 KR 268
            R
Sbjct: 270 NR 271



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 41/118 (34%), Positives = 57/118 (48%), Gaps = 13/118 (11%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L  H+    IH   K + C   G     + F     L  H R HTGEK +
Sbjct: 440 CGKGFNQNTCLTQHMR---IHTGEKPYKCKECG-----KAFAHSSSLTEHHRTHTGEKLY 491

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNE 231
           KC+   C K++ +  +L  H R HTGEKPY C    C K F ++S   +HQ + HS +
Sbjct: 492 KCS--ECEKTFRKYAHLSEHYRIHTGEKPYECIE--CGKFFRHSSVLFRHQ-KLHSGD 544



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 7/87 (8%)

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           T +K  KC    C K++++  +L  H R+HTGE+PY CE   C KAFS +S   +HQ R 
Sbjct: 150 TQKKSWKCN--ECGKTFTQSSSLTQHQRTHTGERPYTCEE--CGKAFSRSSFLVQHQ-RI 204

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKH 254
           H+  KPY C+   C K +   S L +H
Sbjct: 205 HTGVKPYGCE--QCGKTFRCRSFLTQH 229


>gi|197313744 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  103 bits (258), Expect = 6e-22
 Identities = 58/141 (41%), Positives = 74/141 (52%), Gaps = 15/141 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L+HH   + IH   K ++C   G S     F+    L  H R HTGEKPH
Sbjct: 272 CGKAFNQNTHLIHH---QRIHTGEKPYICSECGSS-----FRKHSNLTQHQRIHTGEKPH 323

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K++    NL  H R H+GEKPY C+   C KAF  +    KHQ R H+ EKP
Sbjct: 324 KC--DECGKTFQTKANLSQHQRIHSGEKPYKCKE--CGKAFCQSPSLIKHQ-RIHTGEKP 378

Query: 234 YVCKLPGCTKRYTDPSSLRKH 254
           Y CK   C K +T  + L KH
Sbjct: 379 YKCK--ECGKAFTQSTPLTKH 397



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 54/151 (35%), Positives = 71/151 (47%), Gaps = 15/151 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     LV H   + IH   K +     GC +  + F+ +  L  H R HTGEKP+
Sbjct: 188 CGKAFSRSSFLVQH---QRIHTGVKPY-----GCEQCGKTFRCRSFLTQHQRIHTGEKPY 239

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C  S+    +L  H R HTGEKPY C    C KAF N +    H  R H+ EKP
Sbjct: 240 KC--NECGNSFRNHSHLTEHQRIHTGEKPYKCNR--CGKAF-NQNTHLIHHQRIHTGEKP 294

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAH 264
           Y+C    C   +   S+L +H +   G   H
Sbjct: 295 YICS--ECGSSFRKHSNLTQHQRIHTGEKPH 323



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 54/147 (36%), Positives = 72/147 (48%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H   + IH   K + C   G     + F     L  H R HTGE+P+
Sbjct: 356 CGKAFCQSPSLIKH---QRIHTGEKPYKCKECG-----KAFTQSTPLTKHQRIHTGERPY 407

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC+   C K++ +   L  H RSHTGEKPY C    C K F+  +   +H  R H+ EKP
Sbjct: 408 KCS--ECGKAFIQSICLIRHQRSHTGEKPYKCNE--CGKGFNQNTCLTQHM-RIHTGEKP 462

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y CK   C K +   SSL +H +T  G
Sbjct: 463 YKCK--ECGKAFAHSSSLTEHHRTHTG 487



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 50/143 (34%), Positives = 72/143 (50%), Gaps = 15/143 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L  H   + IH   + + C   G     + F     L+ H R HTGEKP+
Sbjct: 384 CGKAFTQSTPLTKH---QRIHTGERPYKCSECG-----KAFIQSICLIRHQRSHTGEKPY 435

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K +++   L  H+R HTGEKPY C+   C KAF+++S   +H +RTH+ EK 
Sbjct: 436 KCN--ECGKGFNQNTCLTQHMRIHTGEKPYKCKE--CGKAFAHSSSLTEH-HRTHTGEKL 490

Query: 234 YVCKLPGCTKRYTDPSSLRKHVK 256
           Y C    C K +   + L +H +
Sbjct: 491 YKCS--ECEKTFRKYAHLSEHYR 511



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 52/154 (33%), Positives = 76/154 (49%), Gaps = 15/154 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F  +  L  H   + IH   K + C+  G S     F+    L  H R HTGEKP+
Sbjct: 216 CGKTFRCRSFLTQH---QRIHTGEKPYKCNECGNS-----FRNHSHLTEHQRIHTGEKPY 267

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K++++  +L  H R HTGEKPY+C    C  +F   S+  +HQ R H+ EKP
Sbjct: 268 KCN--RCGKAFNQNTHLIHHQRIHTGEKPYICSE--CGSSFRKHSNLTQHQ-RIHTGEKP 322

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTK 267
           + C    C K +   ++L +H +   G   +  K
Sbjct: 323 HKC--DECGKTFQTKANLSQHQRIHSGEKPYKCK 354



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H  S   H   K + C+  G     + F     L  HMR HTGEKP+
Sbjct: 412 CGKAFIQSICLIRHQRS---HTGEKPYKCNECG-----KGFNQNTCLTQHMRIHTGEKPY 463

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K+++   +L  H R+HTGEK Y C    C K F   +  ++H  R H+ EKP
Sbjct: 464 KC--KECGKAFAHSSSLTEHHRTHTGEKLYKCSE--CEKTFRKYAHLSEHY-RIHTGEKP 518

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y C    C K +   S L +H K   G
Sbjct: 519 YEC--IECGKFFRHSSVLFRHQKLHSG 543



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 46/122 (37%), Positives = 59/122 (48%), Gaps = 7/122 (5%)

Query: 147 CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE 206
           C+   + F     L  H R HTGE+P+ C  E C K++SR   L  H R HTG KPY CE
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTC--EECGKAFSRSSFLVQHQRIHTGVKPYGCE 214

Query: 207 HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVT 266
              C K F   S   +HQ R H+ EKPY C    C   + + S L +H +   G   +  
Sbjct: 215 Q--CGKTFRCRSFLTQHQ-RIHTGEKPYKCN--ECGNSFRNHSHLTEHQRIHTGEKPYKC 269

Query: 267 KR 268
            R
Sbjct: 270 NR 271



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 41/118 (34%), Positives = 57/118 (48%), Gaps = 13/118 (11%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L  H+    IH   K + C   G     + F     L  H R HTGEK +
Sbjct: 440 CGKGFNQNTCLTQHMR---IHTGEKPYKCKECG-----KAFAHSSSLTEHHRTHTGEKLY 491

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNE 231
           KC+   C K++ +  +L  H R HTGEKPY C    C K F ++S   +HQ + HS +
Sbjct: 492 KCS--ECEKTFRKYAHLSEHYRIHTGEKPYECIE--CGKFFRHSSVLFRHQ-KLHSGD 544



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 7/87 (8%)

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           T +K  KC    C K++++  +L  H R+HTGE+PY CE   C KAFS +S   +HQ R 
Sbjct: 150 TQKKSWKCN--ECGKTFTQSSSLTQHQRTHTGERPYTCEE--CGKAFSRSSFLVQHQ-RI 204

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKH 254
           H+  KPY C+   C K +   S L +H
Sbjct: 205 HTGVKPYGCE--QCGKTFRCRSFLTQH 229


>gi|197313742 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  103 bits (258), Expect = 6e-22
 Identities = 58/141 (41%), Positives = 74/141 (52%), Gaps = 15/141 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L+HH   + IH   K ++C   G S     F+    L  H R HTGEKPH
Sbjct: 272 CGKAFNQNTHLIHH---QRIHTGEKPYICSECGSS-----FRKHSNLTQHQRIHTGEKPH 323

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K++    NL  H R H+GEKPY C+   C KAF  +    KHQ R H+ EKP
Sbjct: 324 KC--DECGKTFQTKANLSQHQRIHSGEKPYKCKE--CGKAFCQSPSLIKHQ-RIHTGEKP 378

Query: 234 YVCKLPGCTKRYTDPSSLRKH 254
           Y CK   C K +T  + L KH
Sbjct: 379 YKCK--ECGKAFTQSTPLTKH 397



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 54/151 (35%), Positives = 71/151 (47%), Gaps = 15/151 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     LV H   + IH   K +     GC +  + F+ +  L  H R HTGEKP+
Sbjct: 188 CGKAFSRSSFLVQH---QRIHTGVKPY-----GCEQCGKTFRCRSFLTQHQRIHTGEKPY 239

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C  S+    +L  H R HTGEKPY C    C KAF N +    H  R H+ EKP
Sbjct: 240 KC--NECGNSFRNHSHLTEHQRIHTGEKPYKCNR--CGKAF-NQNTHLIHHQRIHTGEKP 294

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAH 264
           Y+C    C   +   S+L +H +   G   H
Sbjct: 295 YICS--ECGSSFRKHSNLTQHQRIHTGEKPH 323



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 54/147 (36%), Positives = 72/147 (48%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H   + IH   K + C   G     + F     L  H R HTGE+P+
Sbjct: 356 CGKAFCQSPSLIKH---QRIHTGEKPYKCKECG-----KAFTQSTPLTKHQRIHTGERPY 407

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC+   C K++ +   L  H RSHTGEKPY C    C K F+  +   +H  R H+ EKP
Sbjct: 408 KCS--ECGKAFIQSICLIRHQRSHTGEKPYKCNE--CGKGFNQNTCLTQHM-RIHTGEKP 462

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y CK   C K +   SSL +H +T  G
Sbjct: 463 YKCK--ECGKAFAHSSSLTEHHRTHTG 487



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 50/143 (34%), Positives = 72/143 (50%), Gaps = 15/143 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L  H   + IH   + + C   G     + F     L+ H R HTGEKP+
Sbjct: 384 CGKAFTQSTPLTKH---QRIHTGERPYKCSECG-----KAFIQSICLIRHQRSHTGEKPY 435

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K +++   L  H+R HTGEKPY C+   C KAF+++S   +H +RTH+ EK 
Sbjct: 436 KCN--ECGKGFNQNTCLTQHMRIHTGEKPYKCKE--CGKAFAHSSSLTEH-HRTHTGEKL 490

Query: 234 YVCKLPGCTKRYTDPSSLRKHVK 256
           Y C    C K +   + L +H +
Sbjct: 491 YKCS--ECEKTFRKYAHLSEHYR 511



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 52/154 (33%), Positives = 76/154 (49%), Gaps = 15/154 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F  +  L  H   + IH   K + C+  G S     F+    L  H R HTGEKP+
Sbjct: 216 CGKTFRCRSFLTQH---QRIHTGEKPYKCNECGNS-----FRNHSHLTEHQRIHTGEKPY 267

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K++++  +L  H R HTGEKPY+C    C  +F   S+  +HQ R H+ EKP
Sbjct: 268 KCN--RCGKAFNQNTHLIHHQRIHTGEKPYICSE--CGSSFRKHSNLTQHQ-RIHTGEKP 322

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTK 267
           + C    C K +   ++L +H +   G   +  K
Sbjct: 323 HKC--DECGKTFQTKANLSQHQRIHSGEKPYKCK 354



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H  S   H   K + C+  G     + F     L  HMR HTGEKP+
Sbjct: 412 CGKAFIQSICLIRHQRS---HTGEKPYKCNECG-----KGFNQNTCLTQHMRIHTGEKPY 463

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K+++   +L  H R+HTGEK Y C    C K F   +  ++H  R H+ EKP
Sbjct: 464 KC--KECGKAFAHSSSLTEHHRTHTGEKLYKCSE--CEKTFRKYAHLSEHY-RIHTGEKP 518

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y C    C K +   S L +H K   G
Sbjct: 519 YEC--IECGKFFRHSSVLFRHQKLHSG 543



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 46/122 (37%), Positives = 59/122 (48%), Gaps = 7/122 (5%)

Query: 147 CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE 206
           C+   + F     L  H R HTGE+P+ C  E C K++SR   L  H R HTG KPY CE
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTC--EECGKAFSRSSFLVQHQRIHTGVKPYGCE 214

Query: 207 HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVT 266
              C K F   S   +HQ R H+ EKPY C    C   + + S L +H +   G   +  
Sbjct: 215 Q--CGKTFRCRSFLTQHQ-RIHTGEKPYKCN--ECGNSFRNHSHLTEHQRIHTGEKPYKC 269

Query: 267 KR 268
            R
Sbjct: 270 NR 271



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 41/118 (34%), Positives = 57/118 (48%), Gaps = 13/118 (11%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L  H+    IH   K + C   G     + F     L  H R HTGEK +
Sbjct: 440 CGKGFNQNTCLTQHMR---IHTGEKPYKCKECG-----KAFAHSSSLTEHHRTHTGEKLY 491

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNE 231
           KC+   C K++ +  +L  H R HTGEKPY C    C K F ++S   +HQ + HS +
Sbjct: 492 KCS--ECEKTFRKYAHLSEHYRIHTGEKPYECIE--CGKFFRHSSVLFRHQ-KLHSGD 544



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 7/87 (8%)

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           T +K  KC    C K++++  +L  H R+HTGE+PY CE   C KAFS +S   +HQ R 
Sbjct: 150 TQKKSWKCN--ECGKTFTQSSSLTQHQRTHTGERPYTCEE--CGKAFSRSSFLVQHQ-RI 204

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKH 254
           H+  KPY C+   C K +   S L +H
Sbjct: 205 HTGVKPYGCE--QCGKTFRCRSFLTQH 229


>gi|21361857 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  103 bits (258), Expect = 6e-22
 Identities = 58/141 (41%), Positives = 74/141 (52%), Gaps = 15/141 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L+HH   + IH   K ++C   G S     F+    L  H R HTGEKPH
Sbjct: 272 CGKAFNQNTHLIHH---QRIHTGEKPYICSECGSS-----FRKHSNLTQHQRIHTGEKPH 323

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K++    NL  H R H+GEKPY C+   C KAF  +    KHQ R H+ EKP
Sbjct: 324 KC--DECGKTFQTKANLSQHQRIHSGEKPYKCKE--CGKAFCQSPSLIKHQ-RIHTGEKP 378

Query: 234 YVCKLPGCTKRYTDPSSLRKH 254
           Y CK   C K +T  + L KH
Sbjct: 379 YKCK--ECGKAFTQSTPLTKH 397



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 54/151 (35%), Positives = 71/151 (47%), Gaps = 15/151 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     LV H   + IH   K +     GC +  + F+ +  L  H R HTGEKP+
Sbjct: 188 CGKAFSRSSFLVQH---QRIHTGVKPY-----GCEQCGKTFRCRSFLTQHQRIHTGEKPY 239

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C  S+    +L  H R HTGEKPY C    C KAF N +    H  R H+ EKP
Sbjct: 240 KC--NECGNSFRNHSHLTEHQRIHTGEKPYKCNR--CGKAF-NQNTHLIHHQRIHTGEKP 294

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAH 264
           Y+C    C   +   S+L +H +   G   H
Sbjct: 295 YICS--ECGSSFRKHSNLTQHQRIHTGEKPH 323



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 54/147 (36%), Positives = 72/147 (48%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H   + IH   K + C   G     + F     L  H R HTGE+P+
Sbjct: 356 CGKAFCQSPSLIKH---QRIHTGEKPYKCKECG-----KAFTQSTPLTKHQRIHTGERPY 407

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC+   C K++ +   L  H RSHTGEKPY C    C K F+  +   +H  R H+ EKP
Sbjct: 408 KCS--ECGKAFIQSICLIRHQRSHTGEKPYKCNE--CGKGFNQNTCLTQHM-RIHTGEKP 462

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y CK   C K +   SSL +H +T  G
Sbjct: 463 YKCK--ECGKAFAHSSSLTEHHRTHTG 487



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 50/143 (34%), Positives = 72/143 (50%), Gaps = 15/143 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L  H   + IH   + + C   G     + F     L+ H R HTGEKP+
Sbjct: 384 CGKAFTQSTPLTKH---QRIHTGERPYKCSECG-----KAFIQSICLIRHQRSHTGEKPY 435

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K +++   L  H+R HTGEKPY C+   C KAF+++S   +H +RTH+ EK 
Sbjct: 436 KCN--ECGKGFNQNTCLTQHMRIHTGEKPYKCKE--CGKAFAHSSSLTEH-HRTHTGEKL 490

Query: 234 YVCKLPGCTKRYTDPSSLRKHVK 256
           Y C    C K +   + L +H +
Sbjct: 491 YKCS--ECEKTFRKYAHLSEHYR 511



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 52/154 (33%), Positives = 76/154 (49%), Gaps = 15/154 (9%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F  +  L  H   + IH   K + C+  G S     F+    L  H R HTGEKP+
Sbjct: 216 CGKTFRCRSFLTQH---QRIHTGEKPYKCNECGNS-----FRNHSHLTEHQRIHTGEKPY 267

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C K++++  +L  H R HTGEKPY+C    C  +F   S+  +HQ R H+ EKP
Sbjct: 268 KCN--RCGKAFNQNTHLIHHQRIHTGEKPYICSE--CGSSFRKHSNLTQHQ-RIHTGEKP 322

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTK 267
           + C    C K +   ++L +H +   G   +  K
Sbjct: 323 HKC--DECGKTFQTKANLSQHQRIHSGEKPYKCK 354



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 15/147 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H  S   H   K + C+  G     + F     L  HMR HTGEKP+
Sbjct: 412 CGKAFIQSICLIRHQRS---HTGEKPYKCNECG-----KGFNQNTCLTQHMRIHTGEKPY 463

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC  + C K+++   +L  H R+HTGEK Y C    C K F   +  ++H  R H+ EKP
Sbjct: 464 KC--KECGKAFAHSSSLTEHHRTHTGEKLYKCSE--CEKTFRKYAHLSEHY-RIHTGEKP 518

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           Y C    C K +   S L +H K   G
Sbjct: 519 YEC--IECGKFFRHSSVLFRHQKLHSG 543



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 46/122 (37%), Positives = 59/122 (48%), Gaps = 7/122 (5%)

Query: 147 CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE 206
           C+   + F     L  H R HTGE+P+ C  E C K++SR   L  H R HTG KPY CE
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTC--EECGKAFSRSSFLVQHQRIHTGVKPYGCE 214

Query: 207 HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVT 266
              C K F   S   +HQ R H+ EKPY C    C   + + S L +H +   G   +  
Sbjct: 215 Q--CGKTFRCRSFLTQHQ-RIHTGEKPYKCN--ECGNSFRNHSHLTEHQRIHTGEKPYKC 269

Query: 267 KR 268
            R
Sbjct: 270 NR 271



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 41/118 (34%), Positives = 57/118 (48%), Gaps = 13/118 (11%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+    L  H+    IH   K + C   G     + F     L  H R HTGEK +
Sbjct: 440 CGKGFNQNTCLTQHMR---IHTGEKPYKCKECG-----KAFAHSSSLTEHHRTHTGEKLY 491

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNE 231
           KC+   C K++ +  +L  H R HTGEKPY C    C K F ++S   +HQ + HS +
Sbjct: 492 KCS--ECEKTFRKYAHLSEHYRIHTGEKPYECIE--CGKFFRHSSVLFRHQ-KLHSGD 544



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 7/87 (8%)

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227
           T +K  KC    C K++++  +L  H R+HTGE+PY CE   C KAFS +S   +HQ R 
Sbjct: 150 TQKKSWKCN--ECGKTFTQSSSLTQHQRTHTGERPYTCEE--CGKAFSRSSFLVQHQ-RI 204

Query: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKH 254
           H+  KPY C+   C K +   S L +H
Sbjct: 205 HTGVKPYGCE--QCGKTFRCRSFLTQH 229


>gi|61676193 zinc finger protein 260 [Homo sapiens]
          Length = 412

 Score =  103 bits (256), Expect = 1e-21
 Identities = 60/143 (41%), Positives = 79/143 (55%), Gaps = 15/143 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F+ +  L  H   E IH   K F C+  G     R F  +  L+ H   HTG+KP 
Sbjct: 141 CGKAFNGKAYLTEH---EKIHTGEKPFECNQCG-----RAFSQKQYLIKHQNIHTGKKPF 192

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC+   C K++S+ ENL  H R HTGEKPY C  +GC KAF   S   +HQ R+H+ EKP
Sbjct: 193 KCS--ECGKAFSQKENLIIHQRIHTGEKPYEC--KGCGKAFIQKSSLIRHQ-RSHTGEKP 247

Query: 234 YVCKLPGCTKRYTDPSSLRKHVK 256
           Y CK   C K ++  S+L +H K
Sbjct: 248 YTCK--ECGKAFSGKSNLTEHEK 268



 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 59/166 (35%), Positives = 85/166 (51%), Gaps = 18/166 (10%)

Query: 89  GREDLEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCS 148
           G+ +L   EK     + E   + + C   F  ++ L+ H N   IH   K + C+  G  
Sbjct: 259 GKSNLTEHEKIH---IGEKPYKCNECGTIFRQKQYLIKHHN---IHTGEKPYECNKCG-- 310

Query: 149 RELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHE 208
              + F     L+VH+R HTG+KP++C  + C K++ +  +L  H+RSHTGEKPY C   
Sbjct: 311 ---KAFSRITSLIVHVRIHTGDKPYEC--KVCGKAFCQSSSLTVHMRSHTGEKPYGCNE- 364

Query: 209 GCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 254
            C KAFS  S  A H  R H+ EKPY C    C K ++  S   +H
Sbjct: 365 -CGKAFSQFSTLALHM-RIHTGEKPYQCS--ECGKAFSQKSHHIRH 406



 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 54/149 (36%), Positives = 73/149 (48%), Gaps = 16/149 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F  +E L+ H   + IH   K + C   GC +    F  +  L+ H R HTGEKP+
Sbjct: 197 CGKAFSQKENLIIH---QRIHTGEKPYECK--GCGKA---FIQKSSLIRHQRSHTGEKPY 248

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
            C  + C K++S   NL  H + H GEKPY C    C   F       KH N  H+ EKP
Sbjct: 249 TC--KECGKAFSGKSNLTEHEKIHIGEKPYKCNE--CGTIFRQKQYLIKHHN-IHTGEKP 303

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKTVHGPD 262
           Y C    C K ++  +SL  HV+ +H  D
Sbjct: 304 YECN--KCGKAFSRITSLIVHVR-IHTGD 329



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 57/180 (31%), Positives = 85/180 (47%), Gaps = 30/180 (16%)

Query: 83  LLGMLDGRED----LEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERK 138
           ++GML+  +     L+ ++    E  YE +     C + F  ++ LV H   + +H   K
Sbjct: 1   MIGMLESLQHESDLLQHDQIHTGEKPYECN----ECRKTFSLKQNLVEH---KKMHTGEK 53

Query: 139 EFVCHWGG--CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRS 196
              C   G  CSR          L +H+R HTG+K +KC    C K++S+ EN  +H + 
Sbjct: 54  SHECTECGKVCSRVSS-------LTLHLRSHTGKKAYKCN--KCGKAFSQKENFLSHQKH 104

Query: 197 HTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVK 256
           HTGEKPY CE     K         +HQ + H+  KPY CK   C K +   + L +H K
Sbjct: 105 HTGEKPYECE-----KVSIQMPTIIRHQ-KNHTGTKPYACK--ECGKAFNGKAYLTEHEK 156



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 46/117 (39%), Positives = 59/117 (50%), Gaps = 13/117 (11%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     L+ H+    IH   K + C   G     + F     L VHMR HTGEKP+
Sbjct: 309 CGKAFSRITSLIVHVR---IHTGDKPYECKVCG-----KAFCQSSSLTVHMRSHTGEKPY 360

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSN 230
            C    C K++S+   L  H+R HTGEKPY C    C KAFS  S   +HQ R H++
Sbjct: 361 GCN--ECGKAFSQFSTLALHMRIHTGEKPYQCSE--CGKAFSQKSHHIRHQ-RIHTH 412


>gi|148596977 zinc finger protein 31 [Homo sapiens]
          Length = 1043

 Score =  102 bits (254), Expect = 2e-21
 Identities = 83/259 (32%), Positives = 117/259 (45%), Gaps = 29/259 (11%)

Query: 65  EPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDSQEQL 124
           E L G +S   +  +  PL    D  ED E E + E +    +  +W    QE  S+E L
Sbjct: 643 EGLPGALSKCPTEAVCQPL----DWGEDSENENEDEGQWGNPSQEQW----QESSSEEDL 694

Query: 125 VHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSY 184
              I+ + ++   K + C    C   ++ F      + H R HTGEKP+KC    C K++
Sbjct: 695 EKLIDHQGLYLAEKPYKCDT--C---MKSFSRSSHFIAHQRIHTGEKPYKCL--ECGKNF 747

Query: 185 SRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKR 244
           S   NL TH R HTGEKPY C    C K+FS+ S+   HQ R H+ EKPY C    C K 
Sbjct: 748 SDRSNLNTHQRIHTGEKPYKCLE--CGKSFSDHSNLITHQ-RIHTGEKPYKC--GECWKS 802

Query: 245 YTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESRLTVP 304
           +   S+L KH +   G +        G+    ++PS S        E  P +       P
Sbjct: 803 FNQSSNLLKHQRIHLGGNPDQCSEPGGN--FAQSPSFSAHWRNSTEETAPEQ-------P 853

Query: 305 EGAMKPQPSPGAQSSCSSD 323
           +   K   SPG  S+ S +
Sbjct: 854 QSISKDLNSPGPHSTNSGE 872



 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 56/151 (37%), Positives = 70/151 (46%), Gaps = 17/151 (11%)

Query: 114  CSQEFDSQEQLVHHINSEHIHGERKEFVC-HWGGCSRELRPFKAQYMLVVHMRRHTGEKP 172
            C + F     L +H   +  H   K + C   G C      F  +  L+ H R HTGEKP
Sbjct: 908  CGKSFSKSSTLANH---QRTHTGEKPYKCVDCGKC------FSERSKLITHQRVHTGEKP 958

Query: 173  HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK 232
            +KC    C K +    NL TH R HTGEKPY C    C K F+ +S    HQ R H+ EK
Sbjct: 959  YKCL--ECGKFFRDRSNLITHQRIHTGEKPYKCRE--CGKCFNQSSSLIIHQ-RIHTGEK 1013

Query: 233  PYVCKLPGCTKRYTDPSSLRKHVKTVHGPDA 263
            PY C    C K + + S    H +T  G  A
Sbjct: 1014 PYKC--TECGKDFNNSSHFSAHRRTHAGGKA 1042



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 49/108 (45%), Positives = 58/108 (53%), Gaps = 7/108 (6%)

Query: 147 CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE 206
           CS   R F     L+ H R HTGEKP++C    C KS+S+   L  H R+HTGEKPY C 
Sbjct: 877 CSECGRSFSKSSALISHQRIHTGEKPYECA--ECGKSFSKSSTLANHQRTHTGEKPYKC- 933

Query: 207 HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 254
              C K FS  S    HQ R H+ EKPY C    C K + D S+L  H
Sbjct: 934 -VDCGKCFSERSKLITHQ-RVHTGEKPYKCL--ECGKFFRDRSNLITH 977


>gi|155029531 zinc finger protein 774 [Homo sapiens]
          Length = 483

 Score =  102 bits (254), Expect = 2e-21
 Identities = 60/158 (37%), Positives = 81/158 (51%), Gaps = 21/158 (13%)

Query: 113 GCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKP 172
           GC ++F     L+ H   +  H   + + C   G     + F  +  L++H R HTGEKP
Sbjct: 211 GCEKKFSDSSTLIKH---QRTHTGERPYECPECG-----KTFGRKPHLIMHQRTHTGEKP 262

Query: 173 HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK 232
           + C    C KS+SR  N  TH R+HTG KPY C    C ++FS +SD  KHQ RTH+ E+
Sbjct: 263 YACL--ECHKSFSRSSNFITHQRTHTGVKPYRC--NDCGESFSQSSDLIKHQ-RTHTGER 317

Query: 233 PYVCKLPGCTKRYTDPSSLRKHVKTVHG------PDAH 264
           P+ C  P C K + D S    H+ T  G      PD H
Sbjct: 318 PFKC--PECGKGFRDSSHFVAHMSTHSGERPFSCPDCH 353



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 48/114 (42%), Positives = 65/114 (57%), Gaps = 7/114 (6%)

Query: 147 CSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE 206
           C+   + F     L+ H+R HTGE+P+ C    C K + +  +L TH R+HTGEKPY C 
Sbjct: 153 CAECGKSFNQSSYLIRHLRTHTGERPYTCI--ECGKGFKQSSDLVTHRRTHTGEKPYQC- 209

Query: 207 HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
            +GC K FS++S   KHQ RTH+ E+PY C  P C K +     L  H +T  G
Sbjct: 210 -KGCEKKFSDSSTLIKHQ-RTHTGERPYEC--PECGKTFGRKPHLIMHQRTHTG 259



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 50/145 (34%), Positives = 72/145 (49%), Gaps = 15/145 (10%)

Query: 110 RWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTG 169
           R + C + F     L+ H   +  H   + F C   G     + F+     V HM  H+G
Sbjct: 292 RCNDCGESFSQSSDLIKH---QRTHTGERPFKCPECG-----KGFRDSSHFVAHMSTHSG 343

Query: 170 EKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHS 229
           E+P  C    C KS+S+  +L TH R+HTGE+P+ CE+  C K F+++S   KHQ R H+
Sbjct: 344 ERPFSCP--DCHKSFSQSSHLVTHQRTHTGERPFKCEN--CGKGFADSSALIKHQ-RIHT 398

Query: 230 NEKPYVCKLPGCTKRYTDPSSLRKH 254
            E+PY C    C K +   S    H
Sbjct: 399 GERPYKC--GECGKSFNQSSHFITH 421



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 49/144 (34%), Positives = 67/144 (46%), Gaps = 15/144 (10%)

Query: 114 CSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPH 173
           C + F     LV H   +  H   + F C   G     + F     L+ H R HTGE+P+
Sbjct: 352 CHKSFSQSSHLVTH---QRTHTGERPFKCENCG-----KGFADSSALIKHQRIHTGERPY 403

Query: 174 KCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKP 233
           KC    C KS+++  +  TH R H G++PY C    C K F+  S    HQ RTH+ EKP
Sbjct: 404 KCG--ECGKSFNQSSHFITHQRIHLGDRPYRCPE--CGKTFNQRSHFLTHQ-RTHTGEKP 458

Query: 234 YVCKLPGCTKRYTDPSSLRKHVKT 257
           + C    C K +   + L  H  T
Sbjct: 459 FHCS--KCNKSFRQKAHLLCHQNT 480



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 60/123 (48%), Gaps = 13/123 (10%)

Query: 106 ETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMR 165
           E   + + C + F     L+ H   + IH   + + C  G C +    F      + H R
Sbjct: 372 ERPFKCENCGKGFADSSALIKH---QRIHTGERPYKC--GECGKS---FNQSSHFITHQR 423

Query: 166 RHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQN 225
            H G++P++C    C K++++  +  TH R+HTGEKP+ C    C+K+F   +    HQN
Sbjct: 424 IHLGDRPYRCP--ECGKTFNQRSHFLTHQRTHTGEKPFHCSK--CNKSFRQKAHLLCHQN 479

Query: 226 RTH 228
            TH
Sbjct: 480 -TH 481



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 63/238 (26%), Positives = 90/238 (37%), Gaps = 52/238 (21%)

Query: 58  LVGKCREEPLE----GDMSSPNSTGIQDP-LLGMLDGRED-----LEREEKREPESVYET 107
           L G C E PL+      +      GI  P ++   + +E+     L+  E R+      T
Sbjct: 11  LPGHCLENPLQECHPAQLEEWALKGISRPSVISQPEQKEEPWVLPLQNFEARKIPRESHT 70

Query: 108 DCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRH 167
           DC         D+ E       S     +       WGG   +    + Q+         
Sbjct: 71  DCEHQVAKLNQDNSETAEQCGTSSERTNKDLSHTLSWGGNWEQGLELEGQH--------- 121

Query: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE-----------------HEG- 209
            G  P     EG  +S+S+  +L   L  + GEKP   E                 H G 
Sbjct: 122 -GTLPG----EGQLESFSQERDLNKLLDGYVGEKPMCAECGKSFNQSSYLIRHLRTHTGE 176

Query: 210 -------CSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
                  C K F  +SD   H+ RTH+ EKPY CK  GC K+++D S+L KH +T  G
Sbjct: 177 RPYTCIECGKGFKQSSDLVTHR-RTHTGEKPYQCK--GCEKKFSDSSTLIKHQRTHTG 231


>gi|65508004 Wilms tumor 1 isoform D [Homo sapiens]
          Length = 517

 Score =  101 bits (252), Expect = 3e-21
 Identities = 50/122 (40%), Positives = 75/122 (61%), Gaps = 9/122 (7%)

Query: 136 ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 195
           E++ F+C + GC++  R FK  + L +H R+HTGEKP++C F+ C + +SR + LK H R
Sbjct: 387 EKRPFMCAYPGCNK--RYFKLSH-LQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQR 443

Query: 196 SHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTH---SNEKPYVCKLPGCTKRYTDPSSLR 252
            HTG KP+ C  + C + FS  SD  K   RTH   ++EKP+ C+ P C K++     L 
Sbjct: 444 RHTGVKPFQC--KTCQRKFSR-SDHLKTHTRTHTGKTSEKPFSCRWPSCQKKFARSDELV 500

Query: 253 KH 254
           +H
Sbjct: 501 RH 502



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 39/101 (38%), Positives = 56/101 (55%), Gaps = 4/101 (3%)

Query: 161 VVHMRRHTGEK-PHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 219
           +V     T EK P  C + GC K Y +L +L+ H R HTGEKPY C+ + C + FS  SD
Sbjct: 378 LVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSR-SD 436

Query: 220 RAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHG 260
           + K   R H+  KP+ CK   C ++++    L+ H +T  G
Sbjct: 437 QLKRHQRRHTGVKPFQCKT--CQRKFSRSDHLKTHTRTHTG 475



 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 20/158 (12%)

Query: 85  GMLDGREDLEREEKREP---ESVYETD------CRWDGCSQEFDSQEQLVHHINSEHIHG 135
           G+  G +D+ R     P    S  ET       C + GC++ +     L  H      H 
Sbjct: 360 GVFRGIQDVRRVPGVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRK---HT 416

Query: 136 ERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 195
             K + C +  C R    F     L  H RRHTG KP +C  + C++ +SR ++LKTH R
Sbjct: 417 GEKPYQCDFKDCERR---FSRSDQLKRHQRRHTGVKPFQC--KTCQRKFSRSDHLKTHTR 471

Query: 196 SHTG---EKPYMCEHEGCSKAFSNASDRAKHQNRTHSN 230
           +HTG   EKP+ C    C K F+ + +  +H N    N
Sbjct: 472 THTGKTSEKPFSCRWPSCQKKFARSDELVRHHNMHQRN 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,336,466
Number of Sequences: 37866
Number of extensions: 3792583
Number of successful extensions: 43195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1025
Number of HSP's successfully gapped in prelim test: 929
Number of HSP's that attempted gapping in prelim test: 12976
Number of HSP's gapped (non-prelim): 11090
length of query: 978
length of database: 18,247,518
effective HSP length: 112
effective length of query: 866
effective length of database: 14,006,526
effective search space: 12129651516
effective search space used: 12129651516
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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