Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 22748979

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748979 transmembrane protein 199 [Homo sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748979 transmembrane protein 199 [Homo sapiens]                  401   e-112
gi|171543850 RUN domain containing 1 [Homo sapiens]                    29   2.5  
gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho...    29   3.2  
gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho...    29   3.2  
gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho...    29   3.2  
gi|239754182 PREDICTED: hypothetical protein [Homo sapiens]            28   4.2  
gi|239748704 PREDICTED: hypothetical protein XP_002346777 [Homo ...    28   4.2  
gi|239742735 PREDICTED: hypothetical protein XP_002342625 [Homo ...    28   4.2  
gi|130502140 NEZHA isoform 2 [Homo sapiens]                            28   4.2  
gi|122937255 NEZHA isoform 1 [Homo sapiens]                            28   4.2  
gi|156104874 envoplakin [Homo sapiens]                                 28   4.2  
gi|33359682 ephrin A1 isoform a precursor [Homo sapiens]               28   4.2  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           28   5.5  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           28   5.5  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           28   5.5  
gi|38202246 syntaphilin [Homo sapiens]                                 28   5.5  
gi|45446749 kinesin family member 5A [Homo sapiens]                    28   7.2  
gi|7705939 Rap guanine nucleotide exchange factor (GEF)-like 1 [...    28   7.2  
gi|14670354 general transcription factor II, i isoform 3 [Homo s...    27   9.4  
gi|14670352 general transcription factor II, i isoform 2 [Homo s...    27   9.4  
gi|14670350 general transcription factor II, i isoform 1 [Homo s...    27   9.4  
gi|169881252 general transcription factor II, i isoform 4 [Homo ...    27   9.4  
gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide ...    27   9.4  
gi|46559747 hypothetical protein LOC399947 [Homo sapiens]              27   9.4  

>gi|22748979 transmembrane protein 199 [Homo sapiens]
          Length = 208

 Score =  401 bits (1031), Expect = e-112
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MASSLLAGERLVRALGPGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLI 60
           MASSLLAGERLVRALGPGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLI
Sbjct: 1   MASSLLAGERLVRALGPGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLI 60

Query: 61  RDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITR 120
           RDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITR
Sbjct: 61  RDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITR 120

Query: 121 NVTCQDTRHGGTLSDLGKQVRSLKALVITIFNFIVTVVAAFVCTYLGSQYIFTEMASRVL 180
           NVTCQDTRHGGTLSDLGKQVRSLKALVITIFNFIVTVVAAFVCTYLGSQYIFTEMASRVL
Sbjct: 121 NVTCQDTRHGGTLSDLGKQVRSLKALVITIFNFIVTVVAAFVCTYLGSQYIFTEMASRVL 180

Query: 181 AALIVASVVGLAELYVMVRAMEGELGEL 208
           AALIVASVVGLAELYVMVRAMEGELGEL
Sbjct: 181 AALIVASVVGLAELYVMVRAMEGELGEL 208


>gi|171543850 RUN domain containing 1 [Homo sapiens]
          Length = 613

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 52  QRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLA 111
           QR++   LI+ L  +L E  S L   EL +  +  + ++V P R  E +  +E++K Q+ 
Sbjct: 218 QRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQL--VEQLKTQIR 275

Query: 112 NEE 114
           + E
Sbjct: 276 DLE 278


>gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo
           sapiens]
          Length = 1645

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 54  LVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANE 113
           L+    I+  H+H++E+  K  + E  E SE+       PP +P  +A L    I+LA E
Sbjct: 310 LIHIENIQGAHKHIKEKRHKKNILEKQEESELR----SLPPPSPAHLAALSVAVIELAKE 365


>gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo
           sapiens]
          Length = 1644

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 54  LVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANE 113
           L+    I+  H+H++E+  K  + E  E SE+       PP +P  +A L    I+LA E
Sbjct: 310 LIHIENIQGAHKHIKEKRHKKNILEKQEESELR----SLPPPSPAHLAALSVAVIELAKE 365


>gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo
           sapiens]
          Length = 1640

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 54  LVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANE 113
           L+    I+  H+H++E+  K  + E  E SE+       PP +P  +A L    I+LA E
Sbjct: 310 LIHIENIQGAHKHIKEKRHKKNILEKQEESELR----SLPPPSPAHLAALSVAVIELAKE 365


>gi|239754182 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 136

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)

Query: 37 ALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEG 82
          A G   +GG  S G   +    L+RD  Q L +R     LH+LLEG
Sbjct: 40 AAGVPTRGGIGSEGQAEVEGLYLLRDGQQDLVQR-----LHQLLEG 80


>gi|239748704 PREDICTED: hypothetical protein XP_002346777 [Homo
          sapiens]
          Length = 136

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)

Query: 37 ALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEG 82
          A G   +GG  S G   +    L+RD  Q L +R     LH+LLEG
Sbjct: 40 AAGVPTRGGIGSEGQAEVEGLYLLRDGQQDLVQR-----LHQLLEG 80


>gi|239742735 PREDICTED: hypothetical protein XP_002342625 [Homo
          sapiens]
          Length = 136

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)

Query: 37 ALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEG 82
          A G   +GG  S G   +    L+RD  Q L +R     LH+LLEG
Sbjct: 40 AAGVPTRGGIGSEGQAEVEGLYLLRDGQQDLVQR-----LHQLLEG 80


>gi|130502140 NEZHA isoform 2 [Homo sapiens]
          Length = 1249

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 15/113 (13%)

Query: 13   RALGPGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDS 72
            RA  P G + P RLP     + E         G ++S P  +  +   R L++    + +
Sbjct: 1071 RAPSPSGLMSPSRLPGSRERDWE--------NGSNASSPASVPEYTGPR-LYKEPSAKSN 1121

Query: 73   KLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQ 125
            K  +H  L  S   L   V  P+   ++  +EK K       +  + R+ +CQ
Sbjct: 1122 KFIIHNAL--SHCCLAGKVNEPQKNRILEEIEKSKA----NHFLILFRDSSCQ 1168


>gi|122937255 NEZHA isoform 1 [Homo sapiens]
          Length = 1276

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 15/113 (13%)

Query: 13   RALGPGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDS 72
            RA  P G + P RLP     + E         G ++S P  +  +   R L++    + +
Sbjct: 1098 RAPSPSGLMSPSRLPGSRERDWE--------NGSNASSPASVPEYTGPR-LYKEPSAKSN 1148

Query: 73   KLYLHELLEGSEIYLPEVVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQ 125
            K  +H  L  S   L   V  P+   ++  +EK K       +  + R+ +CQ
Sbjct: 1149 KFIIHNAL--SHCCLAGKVNEPQKNRILEEIEKSKA----NHFLILFRDSSCQ 1195


>gi|156104874 envoplakin [Homo sapiens]
          Length = 2033

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 16/89 (17%)

Query: 22   EPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLE 81
            E E+   +L+A+L+   GK+       SG ++ V  +L+ DL + LR +   +   E+ +
Sbjct: 1205 ETEQEITRLKAKLQEMAGKR-------SGVEKEVE-KLLPDL-EVLRAQKPTVEYKEVTQ 1255

Query: 82   GSEIYLPEVVKPPRNPELVARLEKIKIQL 110
                   EVV+  R+PE++  ++++K QL
Sbjct: 1256 -------EVVRHERSPEVLREIDRLKAQL 1277


>gi|33359682 ephrin A1 isoform a precursor [Homo sapiens]
          Length = 205

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 11/92 (11%)

Query: 17  PGGELEPERLPRKLRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYL 76
           P  +  PE+L  K +      LGK+ K G S         + + + +HQH    D  L L
Sbjct: 95  PSAKHGPEKLSEKFQRFTPFTLGKEFKEGHS--------YYYISKPIHQH---EDRCLRL 143

Query: 77  HELLEGSEIYLPEVVKPPRNPELVARLEKIKI 108
              + G   + P+    P+   L A   ++++
Sbjct: 144 KVTVSGKITHSPQAHDNPQEKRLAADDPEVRV 175


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 11   LVRALGPGGEL--EPERLPRKLRAELEAALGKKHKGGDSSSGPQRL--VSFRLIRDLHQH 66
            L RAL    E   E ER  R LRAELEA L  K   G S    +R   V+ +   DL   
Sbjct: 1513 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1572

Query: 67   LRERDSKL 74
            + E + +L
Sbjct: 1573 VTELEDEL 1580


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 11   LVRALGPGGEL--EPERLPRKLRAELEAALGKKHKGGDSSSGPQRL--VSFRLIRDLHQH 66
            L RAL    E   E ER  R LRAELEA L  K   G S    +R   V+ +   DL   
Sbjct: 1505 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1564

Query: 67   LRERDSKL 74
            + E + +L
Sbjct: 1565 VTELEDEL 1572


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 11   LVRALGPGGEL--EPERLPRKLRAELEAALGKKHKGGDSSSGPQRL--VSFRLIRDLHQH 66
            L RAL    E   E ER  R LRAELEA L  K   G S    +R   V+ +   DL   
Sbjct: 1546 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1605

Query: 67   LRERDSKL 74
            + E + +L
Sbjct: 1606 VTELEDEL 1613


>gi|38202246 syntaphilin [Homo sapiens]
          Length = 494

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 23/126 (18%)

Query: 42  HKGGDSSSGPQRLVSFRLIRDLH--------QHLRERDSK----LYLHELLEGSEIYLPE 89
           +KG DSS  P+R + + L  D H        Q+L     K     +L   L+ ++  L +
Sbjct: 43  YKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQD 102

Query: 90  VVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVIT 149
             +     +L  +L +++     EE  R+   +  ++ R         K+++ LK ++ T
Sbjct: 103 --RDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEAR---------KEIKQLKQVIDT 151

Query: 150 IFNFIV 155
           + N ++
Sbjct: 152 VKNNLI 157


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 1/57 (1%)

Query: 35  EAALGKKHKGGDSSSGPQRL-VSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPEV 90
           + + GK H        PQ + +  R+ RD+  H+   D  L  H  +   EIYL ++
Sbjct: 87  QTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKI 143


>gi|7705939 Rap guanine nucleotide exchange factor (GEF)-like 1
          [Homo sapiens]
          Length = 456

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%)

Query: 63 LHQHLRERDSKLYLHELLEGSEIYLPEVVKPP 94
          L+Q LRE    L LH+L+E  E+ +PE  +PP
Sbjct: 51 LYQGLRE--DTLRLHQLVETVELKIPEENQPP 80


>gi|14670354 general transcription factor II, i isoform 3 [Homo
           sapiens]
          Length = 977

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 8/122 (6%)

Query: 30  LRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPE 89
           LR ++E    +K+     + GP   + + L +    H+ +    LY+  L EG     P 
Sbjct: 340 LRKQVEELFERKYAQAIKAKGPVT-IPYPLFQS---HVED----LYVEGLPEGIPFRRPS 391

Query: 90  VVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVIT 149
               PR   ++   E+I+  +   E    TR     D    G   +   ++  L+ +V  
Sbjct: 392 TYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQ 451

Query: 150 IF 151
           +F
Sbjct: 452 LF 453


>gi|14670352 general transcription factor II, i isoform 2 [Homo
           sapiens]
          Length = 978

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 8/122 (6%)

Query: 30  LRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPE 89
           LR ++E    +K+     + GP   + + L +    H+ +    LY+  L EG     P 
Sbjct: 341 LRKQVEELFERKYAQAIKAKGPVT-IPYPLFQS---HVED----LYVEGLPEGIPFRRPS 392

Query: 90  VVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVIT 149
               PR   ++   E+I+  +   E    TR     D    G   +   ++  L+ +V  
Sbjct: 393 TYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQ 452

Query: 150 IF 151
           +F
Sbjct: 453 LF 454


>gi|14670350 general transcription factor II, i isoform 1 [Homo
           sapiens]
          Length = 998

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 8/122 (6%)

Query: 30  LRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPE 89
           LR ++E    +K+     + GP   + + L +    H+ +    LY+  L EG     P 
Sbjct: 361 LRKQVEELFERKYAQAIKAKGPVT-IPYPLFQS---HVED----LYVEGLPEGIPFRRPS 412

Query: 90  VVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVIT 149
               PR   ++   E+I+  +   E    TR     D    G   +   ++  L+ +V  
Sbjct: 413 TYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQ 472

Query: 150 IF 151
           +F
Sbjct: 473 LF 474


>gi|169881252 general transcription factor II, i isoform 4 [Homo
           sapiens]
          Length = 957

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 26/122 (21%), Positives = 48/122 (39%), Gaps = 8/122 (6%)

Query: 30  LRAELEAALGKKHKGGDSSSGPQRLVSFRLIRDLHQHLRERDSKLYLHELLEGSEIYLPE 89
           LR ++E    +K+     + GP   + + L +    H+ +    LY+  L EG     P 
Sbjct: 320 LRKQVEELFERKYAQAIKAKGPVT-IPYPLFQS---HVED----LYVEGLPEGIPFRRPS 371

Query: 90  VVKPPRNPELVARLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQVRSLKALVIT 149
               PR   ++   E+I+  +   E    TR     D    G   +   ++  L+ +V  
Sbjct: 372 TYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQ 431

Query: 150 IF 151
           +F
Sbjct: 432 LF 433


>gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide 1
           [Homo sapiens]
          Length = 512

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 13/31 (41%), Positives = 21/31 (67%), Gaps = 3/31 (9%)

Query: 60  IRDLHQHLRERDSKLYLHELLEGSEIYLPEV 90
           I D+H++ R+  SK++ HE LE    YLP++
Sbjct: 134 IGDIHRNKRKVFSKIFSHEALES---YLPKI 161


>gi|46559747 hypothetical protein LOC399947 [Homo sapiens]
          Length = 197

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 4/38 (10%)

Query: 102 RLEKIKIQLANEEYKRITRNVTCQDTRHGGTLSDLGKQ 139
           R++K K+Q A EEY+R      C  +R GG L   G+Q
Sbjct: 88  RMKKRKMQRAQEEYER----DHCSGSRGGGGLPRPGRQ 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,348,933
Number of Sequences: 37866
Number of extensions: 315588
Number of successful extensions: 1061
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1050
Number of HSP's gapped (non-prelim): 34
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press