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Search of human proteins with 227116325
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227116325 kringle-containing transmembrane protein 1 isoform
3 precursor [Homo sapiens]
(458 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227116325 kringle-containing transmembrane protein 1 isoform ... 969 0.0
gi|24041012 kringle-containing transmembrane protein 1 isoform 2... 952 0.0
gi|27437008 kringle-containing transmembrane protein 2 isoform d... 328 6e-90
gi|13375642 kringle-containing transmembrane protein 2 isoform b... 327 1e-89
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 84 3e-16
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 84 3e-16
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 84 3e-16
gi|4504383 HGF activator preproprotein [Homo sapiens] 75 9e-14
gi|4505881 plasminogen [Homo sapiens] 70 4e-12
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 69 9e-12
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 69 9e-12
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 69 9e-12
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 69 1e-11
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s... 68 2e-11
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s... 68 2e-11
gi|145275213 coagulation factor XII precursor [Homo sapiens] 68 2e-11
gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 67 3e-11
gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 67 3e-11
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 67 3e-11
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 67 3e-11
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 65 1e-10
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu... 65 1e-10
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 63 5e-10
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 63 5e-10
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 63 5e-10
gi|134152686 receptor tyrosine kinase-like orphan receptor 1 iso... 62 1e-09
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso... 62 1e-09
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 62 1e-09
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 60 4e-09
gi|54792094 WSC domain containing 1 [Homo sapiens] 54 4e-07
>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
precursor [Homo sapiens]
Length = 458
Score = 969 bits (2504), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW
Sbjct: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
Query: 61 NETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG 120
NETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG
Sbjct: 61 NETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG 120
Query: 121 NLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY 180
NLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY
Sbjct: 121 NLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY 180
Query: 181 GEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGR 240
GEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGR
Sbjct: 181 GEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGR 240
Query: 241 VCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDF 300
VCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDF
Sbjct: 241 VCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDF 300
Query: 301 VILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLY 360
VILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLY
Sbjct: 301 VILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLY 360
Query: 361 VITTSPSHPPQTVPGWTVYGLATLLILTVTAIVAKILLHVTFKSHRVPASGDLRDCHQPG 420
VITTSPSHPPQTVPGWTVYGLATLLILTVTAIVAKILLHVTFKSHRVPASGDLRDCHQPG
Sbjct: 361 VITTSPSHPPQTVPGWTVYGLATLLILTVTAIVAKILLHVTFKSHRVPASGDLRDCHQPG 420
Query: 421 TSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPLVSD 458
TSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPLVSD
Sbjct: 421 TSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPLVSD 458
>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
precursor [Homo sapiens]
Length = 492
Score = 952 bits (2462), Expect = 0.0
Identities = 455/472 (96%), Positives = 455/472 (96%), Gaps = 17/472 (3%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW
Sbjct: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
Query: 61 NETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG 120
NETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG
Sbjct: 61 NETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG 120
Query: 121 NLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY 180
NLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY
Sbjct: 121 NLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY 180
Query: 181 GEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGR 240
GEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGR
Sbjct: 181 GEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGR 240
Query: 241 VCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDF 300
VCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDF
Sbjct: 241 VCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDF 300
Query: 301 VILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLY 360
VILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLY
Sbjct: 301 VILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLY 360
Query: 361 VITTSPSHPPQTVP-----------------GWTVYGLATLLILTVTAIVAKILLHVTFK 403
VITTSPSHPPQTVP GWTVYGLATLLILTVTAIVAKILLHVTFK
Sbjct: 361 VITTSPSHPPQTVPGSNSWAPPMGAGSHRVEGWTVYGLATLLILTVTAIVAKILLHVTFK 420
Query: 404 SHRVPASGDLRDCHQPGTSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPL 455
SHRVPASGDLRDCHQPGTSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPL
Sbjct: 421 SHRVPASGDLRDCHQPGTSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPL 472
>gi|27437008 kringle-containing transmembrane protein 2 isoform d
precursor [Homo sapiens]
Length = 462
Score = 328 bits (841), Expect = 6e-90
Identities = 172/379 (45%), Positives = 234/379 (61%), Gaps = 31/379 (8%)
Query: 25 SPGLGPGPECFTANGADYRGTQNWTALQG-GKPCLFWNETFQHPYNTLKYPNGEGGLGEH 83
SPGL ECF NGADYRG QN T +G G+PCLFW++T QH Y++ P+G GLG H
Sbjct: 30 SPGLS---ECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAH 86
Query: 84 NYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNK 143
N+CRNPDGDV PWCYVAE E+G+YW+YC+IP+C MPG LGC+ D G PP L+G S TS K
Sbjct: 87 NFCRNPDGDVQPWCYVAETEEGIYWRYCDIPSCHMPGYLGCFVDSGAPPALSGPSGTSTK 146
Query: 144 LTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGD 203
LT+Q C+ FCR + ++ AG+E+GYACFCG+ D + A +T+C+ +CFG Q CGGD
Sbjct: 147 LTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRLAPATDCDQICFGHPGQLCGGD 206
Query: 204 GRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDI 263
GR+ +++ VG+C GN++A V+YSPDFPD Y R C W + PGA+ + +F LF++
Sbjct: 207 GRLGVYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWALGPPGAA-LELTFRLFEL 265
Query: 264 RDSADMVELLDGYTHRVLARFHGRSRPPLS--FNVSLDFVILYFFSDRINQAQGFAVLYQ 321
D D +EL D + +L F G +RPP S + ++L F SD AQGFA+ Y+
Sbjct: 266 ADPRDRLELRDAASGSLLRAFDG-ARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYR 324
Query: 322 AVKE--ELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGWTVY 379
+++ E P+ QT A + + AN+S S P PP + G V+
Sbjct: 325 GLQDAAEDPEAPEGSAQTPAAPL-DGANVSCS------------PRPGAPPAAI-GARVF 370
Query: 380 GLATLLILTVTAIVAKILL 398
TVTA+ +LL
Sbjct: 371 S-------TVTAVSVLLLL 382
>gi|13375642 kringle-containing transmembrane protein 2 isoform b
precursor [Homo sapiens]
Length = 420
Score = 327 bits (839), Expect = 1e-89
Identities = 161/332 (48%), Positives = 219/332 (65%), Gaps = 11/332 (3%)
Query: 25 SPGLGPGPECFTANGADYRGTQNWTALQG-GKPCLFWNETFQHPYNTLKYPNGEGGLGEH 83
SPGL ECF NGADYRG QN T +G G+PCLFW++T QH Y++ P+G GLG H
Sbjct: 30 SPGLS---ECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAH 86
Query: 84 NYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNK 143
N+CRNPDGDV PWCYVAE E+G+YW+YC+IP+C MPG LGC+ D G PP L+G S TS K
Sbjct: 87 NFCRNPDGDVQPWCYVAETEEGIYWRYCDIPSCHMPGYLGCFVDSGAPPALSGPSGTSTK 146
Query: 144 LTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGD 203
LT+Q C+ FCR + ++ AG+E+GYACFCG+ D + A +T+C+ +CFG Q CGGD
Sbjct: 147 LTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRLAPATDCDQICFGHPGQLCGGD 206
Query: 204 GRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDI 263
GR+ +++ VG+C GN++A V+YSPDFPD Y R C W + PGA+ + +F LF++
Sbjct: 207 GRLGVYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWALGPPGAA-LELTFRLFEL 265
Query: 264 RDSADMVELLDGYTHRVLARFHGRSRPPLS--FNVSLDFVILYFFSDRINQAQGFAVLYQ 321
D D +EL D + +L F G +RPP S + ++L F SD AQGFA+ Y+
Sbjct: 266 ADPRDRLELRDAASGSLLRAFDG-ARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYR 324
Query: 322 AVKE--ELPQERPAVNQTVAEVITEQANLSVS 351
+++ E P+ QT A + + AN+S S
Sbjct: 325 GLQDAAEDPEAPEGSAQTPAAPL-DGANVSCS 355
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 84.0 bits (206), Expect = 3e-16
Identities = 36/86 (41%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNE--TFQHPYNTLKYPNGEGGLGEHNYCRNPD 90
+C+ +G YRG N T Q CL+WN Q YN G+GEHN+CRNPD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHA--CLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPD 250
Query: 91 GDVSPWCYVAEHEDGVYWKYCEIPAC 116
D PWC++ D V W+YC++ AC
Sbjct: 251 ADEKPWCFIKVTNDKVKWEYCDVSAC 276
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 83.6 bits (205), Expect = 3e-16
Identities = 42/101 (41%), Positives = 59/101 (58%), Gaps = 8/101 (7%)
Query: 22 PAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQ-HPYNTLKYPNGEG-G 79
PA S G +C+ NG+ YRGT + T + G CL WN T + P+ + G
Sbjct: 206 PACSEG---NSDCYFGNGSAYRGTHSLT--ESGASCLPWNSMILIGKVYTAQNPSAQALG 260
Query: 80 LGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG 120
LG+HNYCRNPDGD PWC+V ++ + W+YC++P+C G
Sbjct: 261 LGKHNYCRNPDGDAKPWCHVLKNR-RLTWEYCDVPSCSTCG 300
Score = 78.2 bits (191), Expect = 1e-14
Identities = 42/100 (42%), Positives = 53/100 (53%), Gaps = 8/100 (8%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETF--QHPYNTLKYPNGEGGLGEHNYCRNPDG 91
C+ G YRGT W+ + G C WN + Q PY+ + GLG HNYCRNPD
Sbjct: 127 CYEDQGISYRGT--WSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDR 184
Query: 92 DVSPWCYVAEHEDGVY-WKYCEIPACQMPGNLGCYKDHGN 130
D PWCYV + G Y ++C PAC GN CY +G+
Sbjct: 185 DSKPWCYV--FKAGKYSSEFCSTPACS-EGNSDCYFGNGS 221
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 83.6 bits (205), Expect = 3e-16
Identities = 42/101 (41%), Positives = 59/101 (58%), Gaps = 8/101 (7%)
Query: 22 PAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQ-HPYNTLKYPNGEG-G 79
PA S G +C+ NG+ YRGT + T + G CL WN T + P+ + G
Sbjct: 160 PACSEG---NSDCYFGNGSAYRGTHSLT--ESGASCLPWNSMILIGKVYTAQNPSAQALG 214
Query: 80 LGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPG 120
LG+HNYCRNPDGD PWC+V ++ + W+YC++P+C G
Sbjct: 215 LGKHNYCRNPDGDAKPWCHVLKNR-RLTWEYCDVPSCSTCG 254
Score = 78.2 bits (191), Expect = 1e-14
Identities = 42/100 (42%), Positives = 53/100 (53%), Gaps = 8/100 (8%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETF--QHPYNTLKYPNGEGGLGEHNYCRNPDG 91
C+ G YRGT W+ + G C WN + Q PY+ + GLG HNYCRNPD
Sbjct: 81 CYEDQGISYRGT--WSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDR 138
Query: 92 DVSPWCYVAEHEDGVY-WKYCEIPACQMPGNLGCYKDHGN 130
D PWCYV + G Y ++C PAC GN CY +G+
Sbjct: 139 DSKPWCYV--FKAGKYSSEFCSTPACS-EGNSDCYFGNGS 175
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 75.5 bits (184), Expect = 9e-14
Identities = 41/114 (35%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 10 LLSAAALTLAARPAPSPG----LGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQ 65
L+ A T+ A P G + P CF NG YRG + +A G CL WN
Sbjct: 258 LIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSA--SGLSCLAWNSDLL 315
Query: 66 HPYNTLKYPNGEG--GLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQ 117
+ + GLG H YCRNPD D PWCYV + + + W+YC + AC+
Sbjct: 316 YQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVK-DSALSWEYCRLEACE 368
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 70.1 bits (170), Expect = 4e-12
Identities = 44/135 (32%), Positives = 56/135 (41%), Gaps = 24/135 (17%)
Query: 24 PSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEH 83
P P GP +C G +YRG N G C W+ H +N L E
Sbjct: 265 PPPSSGPTYQCLKGTGENYRG--NVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDE- 321
Query: 84 NYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQ-----------------MPGNLGCYK 126
NYCRNPDG +PWC+ + V W+YC+IP+C P CY
Sbjct: 322 NYCRNPDGKRAPWCHTTNSQ--VRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCY- 378
Query: 127 DHGNPPPLTGTSKTS 141
HG+ GTS T+
Sbjct: 379 -HGDGQSYRGTSSTT 392
Score = 66.2 bits (160), Expect = 6e-11
Identities = 39/108 (36%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 12 SAAALTLAARPAPSPGLGPG-PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNT 70
S+ T P P L P +C+ +G YRGT + T GK C W+ H +
Sbjct: 354 SSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTT--GKKCQSWSSMTPHRHQK 411
Query: 71 L--KYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
YPN GL NYCRNPD D PWC+ + V W+YC + C
Sbjct: 412 TPENYPNA--GL-TMNYCRNPDADKGPWCFTT--DPSVRWEYCNLKKC 454
Score = 63.9 bits (154), Expect = 3e-10
Identities = 39/106 (36%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLK-YPNGEGGLGEHNYCRNPDG 91
+C NG YRG + T G PC W H ++ N GL E NYCRNPDG
Sbjct: 480 DCMFGNGKGYRGKRATTVT--GTPCQDWAAQEPHRHSIFTPETNPRAGL-EKNYCRNPDG 536
Query: 92 DV-SPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTG 136
DV PWCY + YC++P C P + C K P G
Sbjct: 537 DVGGPWCYTTNPRK--LYDYCDVPQCAAP-SFDCGKPQVEPKKCPG 579
Score = 61.6 bits (148), Expect = 1e-09
Identities = 35/86 (40%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC T NG +YRGT + T + G C W+ T H + GL E NYCRNPD D
Sbjct: 102 ECKTGNGKNYRGTMSKT--KNGITCQKWSSTSPHRPRFSPATHPSEGL-EENYCRNPDND 158
Query: 93 -VSPWCYVAEHEDGVYWKYCEIPACQ 117
PWCY + E + YC+I C+
Sbjct: 159 PQGPWCYTTDPEK--RYDYCDILECE 182
Score = 56.6 bits (135), Expect = 5e-08
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 9/89 (10%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTL--KYPNGEGGLGEHNYCRNPD 90
EC +G +Y G + T G C W+ H + + K+PN + NYCRNPD
Sbjct: 184 ECMHCSGENYDGKISKT--MSGLECQAWDSQSPHAHGYIPSKFPNKNL---KKNYCRNPD 238
Query: 91 GDVSPWCYVAEHEDGVYWKYCEIPACQMP 119
++ PWC+ + W+ C+IP C P
Sbjct: 239 RELRPWCFTT--DPNKRWELCDIPRCTTP 265
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 68.9 bits (167), Expect = 9e-12
Identities = 43/123 (34%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG S S V+ SP FP Y + C WTI +P +H F F D +E+ G
Sbjct: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSG 2130
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK-EELPQERP 332
T V+ R G P F+ + + LYF SD QGF ++YQA + + P RP
Sbjct: 2131 SSETSTVIGRLSGPQIPSSLFSTTHE-TSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2189
Query: 333 AVN 335
N
Sbjct: 2190 FRN 2192
Score = 65.5 bits (158), Expect = 1e-10
Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 22/172 (12%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGGN +AM+ +YSP +PD Y + C+W +RVP + I+ +F + D + + DG
Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2302
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVL-YQAVKEELPQERP 332
+ +F G + ++ S + +++ F SD GF VL Y A + + Q P
Sbjct: 2303 PDQNSPQIGQFSGNTALESVYSTS-NQILIKFHSD--FTTSGFFVLSYHAYQLRVCQPPP 2359
Query: 333 AVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGWTVYGLATL 384
V AE++TE + + Y Q +PG+T+ G A L
Sbjct: 2360 PVPN--AEILTEDDEFEI----GDIIRY----------QCLPGFTLVGNAIL 2395
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Query: 203 DGRII---LFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFP 259
DG+++ L CGG++SA S V+ SP +P Y C W I I +F
Sbjct: 839 DGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE 898
Query: 260 LFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFA 317
F + D++E+ DG +L ++G P F+ S +F+ L F +D GF
Sbjct: 899 RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFS-SSNFIYLLFTTDNSRSNNGFK 957
Query: 318 VLYQAV 323
+ Y++V
Sbjct: 958 IHYESV 963
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
C N++A V SPD+P+ Y C WTI S IH SF FD+ D + + DG
Sbjct: 681 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 740
Query: 276 YTHR--VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLY 320
+ +L F G + P + + L F +D +GF + Y
Sbjct: 741 DSPESPILGTFTG-AEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 786
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD- 274
CGG+ S + SP +P+ Y C WT+ V + F+F F + D D + + +
Sbjct: 1027 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1086
Query: 275 GYTHRVLARFHGRSRPPLSFNVSL--DF-VILYFFSDRINQAQGFAVLYQAVKEELPQER 331
G + LAR G PP + N L +F L F SD +GF + + E P E
Sbjct: 1087 GSFTQPLARLTGSDLPP-TINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLE-PCED 1144
Query: 332 PAVNQ 336
P + Q
Sbjct: 1145 PGIPQ 1149
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 9/114 (7%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG ++ + SP FP Y G C W I + I F F + + D + L DG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 276 YTHRV-----LARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 324
+ H L FH PP++ S+ L SD A GF V Y+ ++
Sbjct: 85 HPHPTNFRTRLTGFH--LPPPVTSTKSV--FSLRLTSDFAVSAHGFKVYYEELQ 134
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
+ CGGN + S + SP+FP Y R C WTI V I +F F I + D + +
Sbjct: 1545 IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1604
Query: 273 LDG-YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
DG ++ L S+ P S + + L F SD GF + Y+A E
Sbjct: 1605 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRE 1659
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 200 CGGDGRIILFDTL---VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHF 256
C G GR + L V CG + + ++ SP++P Y C ++I+V I+
Sbjct: 1182 CLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINI 1241
Query: 257 SFPLFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQ 314
S F + D++++ DG T +L F G S L+ + + + + L F SD +
Sbjct: 1242 SARTFHLA-QGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDE 1300
Query: 315 GFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVP 374
GF ++Y + E E P + Q I++Q + + S ++Y P
Sbjct: 1301 GFQLVYTSF-ELSHCEDPGIPQ-FGYKISDQGHFA-----GSTIIYGCN----------P 1343
Query: 375 GWTVYGLATLLILT 388
G+T++G + L +T
Sbjct: 1344 GYTLHGSSLLKCMT 1357
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Query: 215 ACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD 274
ACGG S ++ SP FP+ Y C WTI I F F + + D +E ++
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE-IE 258
Query: 275 GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQ 321
G + PP+ N +++ L+F +D ++ +GF+ YQ
Sbjct: 259 GSEPPTIWLSGMNIPPPIISN--KNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/155 (26%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 174 NPDYWKYGEAA---STECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSP 230
NP Y +G A T NS+ + + P T + CGG + + SP
Sbjct: 1865 NPGYILHGSIAIRCETVPNSLAQWNDSLP-----------TCIVPCGGILTKRKGTILSP 1913
Query: 231 DFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRV--LARFHGRS 288
+P+ Y C W I VP + I F + D ++ DG + L + G +
Sbjct: 1914 GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTT 1973
Query: 289 RPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
P L N + + + L F SD A GF + Y A+
Sbjct: 1974 IPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
Score = 46.2 bits (108), Expect = 6e-05
Identities = 47/158 (29%), Positives = 67/158 (42%), Gaps = 16/158 (10%)
Query: 178 WKYGEAASTECNS--VCFGDHTQPC--GGDGRIILFDTLVGA---CGGNYSAMSSVVYSP 230
+K G + C++ V G T C G DGR L CG + V SP
Sbjct: 1677 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSP 1736
Query: 231 DFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHR-----VLARFH 285
++P Y+ G C ++I VP + F F D+VE+ DG T + L+ H
Sbjct: 1737 NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQ-TSLHDVVEVYDGPTQQSSLLSSLSGSH 1795
Query: 286 GRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
PLS S + + + F S A+GF +YQAV
Sbjct: 1796 SGESLPLS---SGNQITIRFTSVGPITAKGFHFVYQAV 1830
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 213 VGACGGNYSAMSSV-VYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVE 271
+ CGG + SS + SP +P Y C W I V + + F FD S D++
Sbjct: 1371 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR 1430
Query: 272 LLDGYTHR-VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQA 322
+ DG +L + S P + +L+ V + F +D GFA+ + +
Sbjct: 1431 VWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSS 1482
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 224 SSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG--YTHRVL 281
+ V+ SP +PD+Y ++C W+I V +I F D++++ DG VL
Sbjct: 2426 TGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVL 2485
Query: 282 ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERP 332
G + + V L + +D N +GF + Y A P+ P
Sbjct: 2486 ISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPP 2536
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASH-IHFSFPLFDIRDSADMVE 271
V CG N S SP+FP Y + C W I + I +F FD+ D +
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
Query: 272 LLD----GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
+ D G VL G P L ++S + L+ +D + GF V Y+ +++E
Sbjct: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ-MWLHLQTDESVGSVGFKVNYKEIEKE 622
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 68.9 bits (167), Expect = 9e-12
Identities = 43/123 (34%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG S S V+ SP FP Y + C WTI +P +H F F D +E+ G
Sbjct: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSG 2066
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK-EELPQERP 332
T V+ R G P F+ + + LYF SD QGF ++YQA + + P RP
Sbjct: 2067 SSETSTVIGRLSGPQIPSSLFSTTHE-TSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2125
Query: 333 AVN 335
N
Sbjct: 2126 FRN 2128
Score = 65.5 bits (158), Expect = 1e-10
Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 22/172 (12%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGGN +AM+ +YSP +PD Y + C+W +RVP + I+ +F + D + + DG
Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVL-YQAVKEELPQERP 332
+ +F G + ++ S + +++ F SD GF VL Y A + + Q P
Sbjct: 2239 PDQNSPQIGQFSGNTALESVYSTS-NQILIKFHSD--FTTSGFFVLSYHAYQLRVCQPPP 2295
Query: 333 AVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGWTVYGLATL 384
V AE++TE + + Y Q +PG+T+ G A L
Sbjct: 2296 PVPN--AEILTEDDEFEI----GDIIRY----------QCLPGFTLVGNAIL 2331
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Query: 203 DGRII---LFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFP 259
DG+++ L CGG++SA S V+ SP +P Y C W I I +F
Sbjct: 775 DGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE 834
Query: 260 LFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFA 317
F + D++E+ DG +L ++G P F+ S +F+ L F +D GF
Sbjct: 835 RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFS-SSNFIYLLFTTDNSRSNNGFK 893
Query: 318 VLYQAV 323
+ Y++V
Sbjct: 894 IHYESV 899
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
C N++A V SPD+P+ Y C WTI S IH SF FD+ D + + DG
Sbjct: 617 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 676
Query: 276 YTHR--VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLY 320
+ +L F G + P + + L F +D +GF + Y
Sbjct: 677 DSPESPILGTFTG-AEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 722
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD- 274
CGG+ S + SP +P+ Y C WT+ V + F+F F + D D + + +
Sbjct: 963 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1022
Query: 275 GYTHRVLARFHGRSRPPLSFNVSL--DF-VILYFFSDRINQAQGFAVLYQAVKEELPQER 331
G + LAR G PP + N L +F L F SD +GF + + E P E
Sbjct: 1023 GSFTQPLARLTGSDLPP-TINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLE-PCED 1080
Query: 332 PAVNQ 336
P + Q
Sbjct: 1081 PGIPQ 1085
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 9/114 (7%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG ++ + SP FP Y G C W I + I F F + + D + L DG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 276 YTHRV-----LARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 324
+ H L FH PP++ S+ L SD A GF V Y+ ++
Sbjct: 125 HPHPTNFRTRLTGFH--LPPPVTSTKSV--FSLRLTSDFAVSAHGFKVYYEELQ 174
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
+ CGGN + S + SP+FP Y R C WTI V I +F F I + D + +
Sbjct: 1481 IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1540
Query: 273 LDG-YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
DG ++ L S+ P S + + L F SD GF + Y+A E
Sbjct: 1541 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRE 1595
Score = 48.5 bits (114), Expect = 1e-05
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
Query: 215 ACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD 274
ACGG S ++ SP FP+ Y C WTI I F F + + D +E ++
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE-IE 298
Query: 275 GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 324
G + PP+ N +++ L+F +D ++ +GF+ YQ K
Sbjct: 299 GSEPPTIWLSGMNIPPPIISN--KNWLRLHFVTDSNHRYRGFSAPYQVKK 346
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 200 CGGDGRIILFDTL---VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHF 256
C G GR + L V CG + + ++ SP++P Y C ++I+V I+
Sbjct: 1118 CLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINI 1177
Query: 257 SFPLFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQ 314
S F + D++++ DG T +L F G S L+ + + + + L F SD +
Sbjct: 1178 SARTFHLA-QGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDE 1236
Query: 315 GFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVP 374
GF ++Y + E E P + Q I++Q + + S ++Y P
Sbjct: 1237 GFQLVYTSF-ELSHCEDPGIPQ-FGYKISDQGHFA-----GSTIIYGCN----------P 1279
Query: 375 GWTVYGLATLLILT 388
G+T++G + L +T
Sbjct: 1280 GYTLHGSSLLKCMT 1293
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/155 (26%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 174 NPDYWKYGEAA---STECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSP 230
NP Y +G A T NS+ + + P T + CGG + + SP
Sbjct: 1801 NPGYILHGSIAIRCETVPNSLAQWNDSLP-----------TCIVPCGGILTKRKGTILSP 1849
Query: 231 DFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRV--LARFHGRS 288
+P+ Y C W I VP + I F + D ++ DG + L + G +
Sbjct: 1850 GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTT 1909
Query: 289 RPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
P L N + + + L F SD A GF + Y A+
Sbjct: 1910 IPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
Score = 46.2 bits (108), Expect = 6e-05
Identities = 47/158 (29%), Positives = 67/158 (42%), Gaps = 16/158 (10%)
Query: 178 WKYGEAASTECNS--VCFGDHTQPC--GGDGRIILFDTLVGA---CGGNYSAMSSVVYSP 230
+K G + C++ V G T C G DGR L CG + V SP
Sbjct: 1613 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSP 1672
Query: 231 DFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHR-----VLARFH 285
++P Y+ G C ++I VP + F F D+VE+ DG T + L+ H
Sbjct: 1673 NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQ-TSLHDVVEVYDGPTQQSSLLSSLSGSH 1731
Query: 286 GRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
PLS S + + + F S A+GF +YQAV
Sbjct: 1732 SGESLPLS---SGNQITIRFTSVGPITAKGFHFVYQAV 1766
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 213 VGACGGNYSAMSSV-VYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVE 271
+ CGG + SS + SP +P Y C W I V + + F FD S D++
Sbjct: 1307 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR 1366
Query: 272 LLDGYTHR-VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQA 322
+ DG +L + S P + +L+ V + F +D GFA+ + +
Sbjct: 1367 VWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSS 1418
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 224 SSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG--YTHRVL 281
+ V+ SP +PD+Y ++C W+I V +I F D++++ DG VL
Sbjct: 2362 TGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVL 2421
Query: 282 ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERP 332
G + + V L + +D N +GF + Y A P+ P
Sbjct: 2422 ISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPP 2472
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASH-IHFSFPLFDIRDSADMVE 271
V CG N S SP+FP Y + C W I + I +F FD+ D +
Sbjct: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
Query: 272 LLD----GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
+ D G VL G P L ++S + L+ +D + GF V Y+ +++E
Sbjct: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ-MWLHLQTDESVGSVGFKVNYKEIEKE 558
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 68.9 bits (167), Expect = 9e-12
Identities = 43/123 (34%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG S S V+ SP FP Y + C WTI +P +H F F D +E+ G
Sbjct: 2111 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSG 2170
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK-EELPQERP 332
T V+ R G P F+ + + LYF SD QGF ++YQA + + P RP
Sbjct: 2171 SSETSTVIGRLSGPQIPSSLFSTTHE-TSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2229
Query: 333 AVN 335
N
Sbjct: 2230 FRN 2232
Score = 65.5 bits (158), Expect = 1e-10
Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 22/172 (12%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGGN +AM+ +YSP +PD Y + C+W +RVP + I+ +F + D + + DG
Sbjct: 2283 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2342
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVL-YQAVKEELPQERP 332
+ +F G + ++ S + +++ F SD GF VL Y A + + Q P
Sbjct: 2343 PDQNSPQIGQFSGNTALESVYSTS-NQILIKFHSD--FTTSGFFVLSYHAYQLRVCQPPP 2399
Query: 333 AVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGWTVYGLATL 384
V AE++TE + + Y Q +PG+T+ G A L
Sbjct: 2400 PVPN--AEILTEDDEFEI----GDIIRY----------QCLPGFTLVGNAIL 2435
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Query: 203 DGRII---LFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFP 259
DG+++ L CGG++SA S V+ SP +P Y C W I I +F
Sbjct: 879 DGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE 938
Query: 260 LFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFA 317
F + D++E+ DG +L ++G P F+ S +F+ L F +D GF
Sbjct: 939 RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFS-SSNFIYLLFTTDNSRSNNGFK 997
Query: 318 VLYQAV 323
+ Y++V
Sbjct: 998 IHYESV 1003
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
C N++A V SPD+P+ Y C WTI S IH SF FD+ D + + DG
Sbjct: 721 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 780
Query: 276 YTHR--VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLY 320
+ +L F G + P + + L F +D +GF + Y
Sbjct: 781 DSPESPILGTFTG-AEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 826
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD- 274
CGG+ S + SP +P+ Y C WT+ V + F+F F + D D + + +
Sbjct: 1067 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1126
Query: 275 GYTHRVLARFHGRSRPPLSFNVSL--DF-VILYFFSDRINQAQGFAVLYQAVKEELPQER 331
G + LAR G PP + N L +F L F SD +GF + + E P E
Sbjct: 1127 GSFTQPLARLTGSDLPP-TINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLE-PCED 1184
Query: 332 PAVNQ 336
P + Q
Sbjct: 1185 PGIPQ 1189
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 9/114 (7%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG ++ + SP FP Y G C W I + I F F + + D + L DG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 276 YTHRV-----LARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 324
+ H L FH PP++ S+ L SD A GF V Y+ ++
Sbjct: 125 HPHPTNFRTRLTGFH--LPPPVTSTKSV--FSLRLTSDFAVSAHGFKVYYEELQ 174
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
+ CGGN + S + SP+FP Y R C WTI V I +F F I + D + +
Sbjct: 1585 IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1644
Query: 273 LDG-YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
DG ++ L S+ P S + + L F SD GF + Y+A E
Sbjct: 1645 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRE 1699
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 200 CGGDGRIILFDTL---VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHF 256
C G GR + L V CG + + ++ SP++P Y C ++I+V I+
Sbjct: 1222 CLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINI 1281
Query: 257 SFPLFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQ 314
S F + D++++ DG T +L F G S L+ + + + + L F SD +
Sbjct: 1282 SARTFHLA-QGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDE 1340
Query: 315 GFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVP 374
GF ++Y + E E P + Q I++Q + + S ++Y P
Sbjct: 1341 GFQLVYTSF-ELSHCEDPGIPQ-FGYKISDQGHFA-----GSTIIYGCN----------P 1383
Query: 375 GWTVYGLATLLILT 388
G+T++G + L +T
Sbjct: 1384 GYTLHGSSLLKCMT 1397
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Query: 215 ACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD 274
ACGG S ++ SP FP+ Y C WTI I F F + + D +E ++
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE-IE 298
Query: 275 GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQ 321
G + PP+ N +++ L+F +D ++ +GF+ YQ
Sbjct: 299 GSEPPTIWLSGMNIPPPIISN--KNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/155 (26%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 174 NPDYWKYGEAA---STECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSP 230
NP Y +G A T NS+ + + P T + CGG + + SP
Sbjct: 1905 NPGYILHGSIAIRCETVPNSLAQWNDSLP-----------TCIVPCGGILTKRKGTILSP 1953
Query: 231 DFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRV--LARFHGRS 288
+P+ Y C W I VP + I F + D ++ DG + L + G +
Sbjct: 1954 GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTT 2013
Query: 289 RPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
P L N + + + L F SD A GF + Y A+
Sbjct: 2014 IPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2047
Score = 46.2 bits (108), Expect = 6e-05
Identities = 47/158 (29%), Positives = 67/158 (42%), Gaps = 16/158 (10%)
Query: 178 WKYGEAASTECNS--VCFGDHTQPC--GGDGRIILFDTLVGA---CGGNYSAMSSVVYSP 230
+K G + C++ V G T C G DGR L CG + V SP
Sbjct: 1717 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSP 1776
Query: 231 DFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHR-----VLARFH 285
++P Y+ G C ++I VP + F F D+VE+ DG T + L+ H
Sbjct: 1777 NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQ-TSLHDVVEVYDGPTQQSSLLSSLSGSH 1835
Query: 286 GRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
PLS S + + + F S A+GF +YQAV
Sbjct: 1836 SGESLPLS---SGNQITIRFTSVGPITAKGFHFVYQAV 1870
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 213 VGACGGNYSAMSSV-VYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVE 271
+ CGG + SS + SP +P Y C W I V + + F FD S D++
Sbjct: 1411 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR 1470
Query: 272 LLDGYTHR-VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQA 322
+ DG +L + S P + +L+ V + F +D GFA+ + +
Sbjct: 1471 VWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSS 1522
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 224 SSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG--YTHRVL 281
+ V+ SP +PD+Y ++C W+I V +I F D++++ DG VL
Sbjct: 2466 TGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVL 2525
Query: 282 ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERP 332
G + + V L + +D N +GF + Y A P+ P
Sbjct: 2526 ISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPP 2576
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASH-IHFSFPLFDIRDSADMVE 271
V CG N S SP+FP Y + C W I + I +F FD+ D +
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 604
Query: 272 LLD----GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
+ D G VL G P L ++S + L+ +D + GF V Y+ +++E
Sbjct: 605 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ-MWLHLQTDESVGSVGFKVNYKEIEKE 662
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 68.6 bits (166), Expect = 1e-11
Identities = 40/107 (37%), Positives = 55/107 (51%), Gaps = 12/107 (11%)
Query: 12 SAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPY--N 69
S A + A SPG+ +C+ +G YRG+ + T G+ C W+ H +
Sbjct: 1149 STEASSEEAPTEQSPGV---QDCYHGDGQSYRGSFSTTVT--GRTCQSWSSMTPHWHQRT 1203
Query: 70 TLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
T YPN GGL NYCRNPD ++SPWCY + V W+YC + C
Sbjct: 1204 TEYYPN--GGL-TRNYCRNPDAEISPWCYTM--DPNVRWEYCNLTQC 1245
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/180 (30%), Positives = 73/180 (40%), Gaps = 46/180 (25%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 113 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 166
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC-- 116
+ H ++ YPN GL NYCRNPD +P+CY + GV W+YC + C
Sbjct: 167 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDAVAAPYCYT--RDPGVRWEYCNLTQCSD 221
Query: 117 ---------------------------QMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
Q PG CY HGN GT T+ +T +TC
Sbjct: 222 AEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY--HGNGQSYRGTYSTT--VTGRTC 277
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/180 (30%), Positives = 73/180 (40%), Gaps = 46/180 (25%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 227 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 280
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC-- 116
+ H ++ YPN GL NYCRNPD +P+CY + GV W+YC + C
Sbjct: 281 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDAVAAPYCYT--RDPGVRWEYCNLTQCSD 335
Query: 117 ---------------------------QMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
Q PG CY HGN GT T+ +T +TC
Sbjct: 336 AEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY--HGNGQSYRGTYSTT--VTGRTC 391
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/180 (30%), Positives = 73/180 (40%), Gaps = 46/180 (25%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 341 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 394
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC-- 116
+ H ++ YPN GL NYCRNPD +P+CY + GV W+YC + C
Sbjct: 395 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDAVAAPYCYT--RDPGVRWEYCNLTQCSD 449
Query: 117 ---------------------------QMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
Q PG CY HGN GT T+ +T +TC
Sbjct: 450 AEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY--HGNGQSYRGTYSTT--VTGRTC 505
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/180 (30%), Positives = 73/180 (40%), Gaps = 46/180 (25%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 455 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 508
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC-- 116
+ H ++ YPN GL NYCRNPD +P+CY + GV W+YC + C
Sbjct: 509 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDAVAAPYCYT--RDPGVRWEYCNLTQCSD 563
Query: 117 ---------------------------QMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
Q PG CY HGN GT T+ +T +TC
Sbjct: 564 AEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY--HGNGQSYRGTYSTT--VTGRTC 619
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/180 (30%), Positives = 73/180 (40%), Gaps = 46/180 (25%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 569 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 622
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC-- 116
+ H ++ YPN GL NYCRNPD +P+CY + GV W+YC + C
Sbjct: 623 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDAVAAPYCYT--RDPGVRWEYCNLTQCSD 677
Query: 117 ---------------------------QMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
Q PG CY HGN GT T+ +T +TC
Sbjct: 678 AEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY--HGNGQSYRGTYSTT--VTGRTC 733
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/180 (30%), Positives = 73/180 (40%), Gaps = 46/180 (25%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 683 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 736
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC-- 116
+ H ++ YPN GL NYCRNPD +P+CY + GV W+YC + C
Sbjct: 737 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDAVAAPYCYT--RDPGVRWEYCNLTQCSD 791
Query: 117 ---------------------------QMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
Q PG CY HGN GT T+ +T +TC
Sbjct: 792 AEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY--HGNGQSYRGTYSTT--VTGRTC 847
Score = 67.4 bits (163), Expect = 3e-11
Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 9/105 (8%)
Query: 14 AALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYN--TL 71
A T + AP+ +C+ +G YRG+ + T G+ C W+ H + T
Sbjct: 1254 ATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTVT--GRTCQSWSSMTPHWHQRTTE 1311
Query: 72 KYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
YPNG GL NYCRNPD ++ PWCY + V W+YC + C
Sbjct: 1312 YYPNG--GL-TRNYCRNPDAEIRPWCYTM--DPSVRWEYCNLTQC 1351
Score = 67.0 bits (162), Expect = 3e-11
Identities = 48/148 (32%), Positives = 63/148 (42%), Gaps = 42/148 (28%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYN--TLKYPNGEGGLGEHNYCRNPD 90
+C+ +G YRGT + T G+ C W+ H +N T YPN GL NYCRNPD
Sbjct: 27 DCYHGDGQSYRGTYSTTVT--GRTCQAWSSMTPHQHNRTTENYPNA--GL-IMNYCRNPD 81
Query: 91 GDVSPWCYVAEHEDGVYWKYCEIPAC-----------------------------QMPGN 121
+P+CY + GV W+YC + C Q PG
Sbjct: 82 AVAAPYCYT--RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGV 139
Query: 122 LGCYKDHGNPPPLTGTSKTSNKLTIQTC 149
CY HGN GT T+ +T +TC
Sbjct: 140 QECY--HGNGQSYRGTYSTT--VTGRTC 163
Score = 67.0 bits (162), Expect = 3e-11
Identities = 44/116 (37%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 26 PGLGPGPE--CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNT-LKYPNGEGGLGE 82
P LGP E C NG YRG + T G PC W H ++T + N GL E
Sbjct: 1710 PSLGPPSEQDCMFGNGKGYRGKKATTVT--GTPCQEWAAQEPHRHSTFIPGTNKWAGL-E 1766
Query: 83 HNYCRNPDGDVS-PWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGT 137
NYCRNPDGD++ PWCY + YC+IP C + C K P G+
Sbjct: 1767 KNYCRNPDGDINGPWCYTMNPRK--LFDYCDIPLC-ASSSFDCGKPQVEPKKCPGS 1819
Score = 66.6 bits (161), Expect = 4e-11
Identities = 36/101 (35%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Query: 18 LAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNT--LKYPN 75
L + AP+ +C+ +G YRGT + T G+ C W+ H + L YPN
Sbjct: 1372 LPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTIT--GRTCQSWSSMTPHWHRRIPLYYPN 1429
Query: 76 GEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
GL NYCRNPD ++ PWCY + V W+YC + C
Sbjct: 1430 A--GL-TRNYCRNPDAEIRPWCYTM--DPSVRWEYCNLTRC 1465
Score = 64.3 bits (155), Expect = 2e-10
Identities = 41/116 (35%), Positives = 55/116 (47%), Gaps = 13/116 (11%)
Query: 3 PPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNE 62
PP LA S A A +PG+ +C+ G YRGT + T G+ C W+
Sbjct: 1027 PPNVILAP-SLEAFFEQALTEETPGV---QDCYYHYGQSYRGTYSTTVT--GRTCQAWSS 1080
Query: 63 TFQHPYNTL--KYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
H ++ YPN GL NYCRNPD ++ PWCY + V W+YC + C
Sbjct: 1081 MTPHQHSRTPENYPNA--GL-TRNYCRNPDAEIRPWCYTM--DPSVRWEYCNLTQC 1131
Score = 63.9 bits (154), Expect = 3e-10
Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTL--KYPNGEGGLGEHNYCRNPD 90
+C+ NG YRGT + T G+ C W+ H + YPN GL NYCRNPD
Sbjct: 1615 QCYHGNGQSYRGTFSTTVT--GRTCQSWSSMTPHRHQRTPENYPND--GL-TMNYCRNPD 1669
Query: 91 GDVSPWCYVAEHEDGVYWKYCEIPAC 116
D PWC+ + + W+YC + C
Sbjct: 1670 ADTGPWCFTM--DPSIRWEYCNLTRC 1693
Score = 62.8 bits (151), Expect = 6e-10
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 13/118 (11%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG Y+GT T G+ C W
Sbjct: 911 VAPPT----ITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVT--GRTCQAW 964
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
+ H ++ YPN GL + NYCRNPD +PWCY + V W+YC + C
Sbjct: 965 SSMTPHSHSRTPAYYPNA--GLIK-NYCRNPDPVAAPWCYTT--DPSVRWEYCNLTRC 1017
Score = 62.0 bits (149), Expect = 1e-09
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 13/118 (11%)
Query: 1 MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFW 60
+APP + +L + AP+ EC+ NG YRGT + T G+ C W
Sbjct: 797 VAPPT----VTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVT--GRTCQAW 850
Query: 61 NETFQHPYNTLK--YPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
+ H ++ YPN GL NYCRNPD +P+CY + V W+YC + C
Sbjct: 851 SSMTPHSHSRTPEYYPNA--GL-IMNYCRNPDPVAAPYCYT--RDPSVRWEYCNLTQC 903
Score = 62.0 bits (149), Expect = 1e-09
Identities = 38/107 (35%), Positives = 50/107 (46%), Gaps = 12/107 (11%)
Query: 12 SAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTL 71
S A + A P SP + +C+ +G YRG + T G+ C W+ H +
Sbjct: 1483 STEAPSEQAPPEKSPVV---QDCYHGDGRSYRGISSTTVT--GRTCQSWSSMIPHWHQRT 1537
Query: 72 --KYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
YPN GL E NYCRNPD PWCY + V W+YC + C
Sbjct: 1538 PENYPNA--GLTE-NYCRNPDSGKQPWCYTT--DPCVRWEYCNLTQC 1579
>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
Length = 285
Score = 67.8 bits (164), Expect = 2e-11
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 205 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 261
Query: 93 VSPWCYVAEHEDGVYWKYCEIPACQ 117
PWCY + W+YC I C+
Sbjct: 262 PRPWCYTLDPH--TRWEYCAIKTCE 284
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDV 93
C G Y+GT + T + G C W+ H ++ G + NYCRNP G+
Sbjct: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSY------RGKDLQENYCRNPRGEE 179
Query: 94 -SPWCYVAEHEDGVYWKYCEIPAC 116
PWC+ + E V ++ C+IP C
Sbjct: 180 GGPWCFTSNPE--VRYEVCDIPQC 201
>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
Length = 290
Score = 67.8 bits (164), Expect = 2e-11
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 210 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 266
Query: 93 VSPWCYVAEHEDGVYWKYCEIPACQ 117
PWCY + W+YC I C+
Sbjct: 267 PRPWCYTLDPH--TRWEYCAIKTCE 289
Score = 50.8 bits (120), Expect = 2e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 8/85 (9%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG-EHNYCRNPDGD 92
C G Y+GT + T + G C W+ H ++ L P+ G + NYCRNP G+
Sbjct: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSFL--PSSYRGKDLQENYCRNPRGE 183
Query: 93 V-SPWCYVAEHEDGVYWKYCEIPAC 116
PWC+ + E V ++ C+IP C
Sbjct: 184 EGGPWCFTSNPE--VRYEVCDIPQC 206
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 67.8 bits (164), Expect = 2e-11
Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDV 93
C+ G YRG T G PC W + T + GLG H +CRNPD D+
Sbjct: 217 CYDGRGLSYRGLARTTL--SGAPCQPWASEATYRNVTAEQARN-WGLGGHAFCRNPDNDI 273
Query: 94 SPWCYVAEHEDGVYWKYCEIPACQMP 119
PWC+V + D + W+YC++ CQ P
Sbjct: 274 RPWCFVL-NRDRLSWEYCDLAQCQTP 298
>gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 67.4 bits (163), Expect = 3e-11
Identities = 38/103 (36%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 16 LTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTL--KY 73
L L + AP+ EC+ +NG YRGT T G+ C W+ H ++ KY
Sbjct: 10 LLLFLKSAPTETGPSVQECYHSNGQSYRGTYFTTVT--GRTCQAWSSMTPHQHSRTPEKY 67
Query: 74 PNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
PN +G + NYCRNPD PWCY + V W+YC + C
Sbjct: 68 PN-DGLIS--NYCRNPDCSAGPWCYTT--DPNVRWEYCNLTRC 105
>gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 67.4 bits (163), Expect = 3e-11
Identities = 38/103 (36%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 16 LTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTL--KY 73
L L + AP+ EC+ +NG YRGT T G+ C W+ H ++ KY
Sbjct: 10 LLLFLKSAPTETGPSVQECYHSNGQSYRGTYFTTVT--GRTCQAWSSMTPHQHSRTPEKY 67
Query: 74 PNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPAC 116
PN +G + NYCRNPD PWCY + V W+YC + C
Sbjct: 68 PN-DGLIS--NYCRNPDCSAGPWCYTT--DPNVRWEYCNLTRC 105
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 67.0 bits (162), Expect = 3e-11
Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 205 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 261
Query: 93 VSPWCYVAEHEDGVYWKYCEIPAC 116
PWCY + W+YC I C
Sbjct: 262 PRPWCYTLDPH--TRWEYCAIKTC 283
Score = 65.9 bits (159), Expect = 8e-11
Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC G YRGT N + G PC W+ + H ++ L E NYCRNPDG
Sbjct: 299 ECIQGQGEGYRGTVN--TIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRE-NYCRNPDGS 355
Query: 93 VSPWCYVAEHEDGVYWKYC-EIPACQMPGNLGCYKDHG 129
SPWC+ + + YC +IP C M CY+ +G
Sbjct: 356 ESPWCFTT--DPNIRVGYCSQIPNCDMSHGQDCYRGNG 391
Score = 59.3 bits (142), Expect = 7e-09
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 6/95 (6%)
Query: 24 PSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEH 83
P+ + G +C+ NG +Y G N + + G C W++ + + + + L E
Sbjct: 376 PNCDMSHGQDCYRGNGKNYMG--NLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNE- 432
Query: 84 NYCRNPDGDV-SPWCYVAEHEDGVYWKYCEIPACQ 117
NYCRNPD D PWCY + W YC I C+
Sbjct: 433 NYCRNPDDDAHGPWCYTG--NPLIPWDYCPISRCE 465
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDV 93
C G Y+GT + T + G C W+ H ++ G + NYCRNP G+
Sbjct: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSY------RGKDLQENYCRNPRGEE 179
Query: 94 -SPWCYVAEHEDGVYWKYCEIPAC 116
PWC+ + E V ++ C+IP C
Sbjct: 180 GGPWCFTSNPE--VRYEVCDIPQC 201
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 67.0 bits (162), Expect = 3e-11
Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 210 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 266
Query: 93 VSPWCYVAEHEDGVYWKYCEIPAC 116
PWCY + W+YC I C
Sbjct: 267 PRPWCYTLDPH--TRWEYCAIKTC 288
Score = 65.9 bits (159), Expect = 8e-11
Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
EC G YRGT N + G PC W+ + H ++ L E NYCRNPDG
Sbjct: 304 ECIQGQGEGYRGTVN--TIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRE-NYCRNPDGS 360
Query: 93 VSPWCYVAEHEDGVYWKYC-EIPACQMPGNLGCYKDHG 129
SPWC+ + + YC +IP C M CY+ +G
Sbjct: 361 ESPWCFTT--DPNIRVGYCSQIPNCDMSHGQDCYRGNG 396
Score = 59.3 bits (142), Expect = 7e-09
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 6/95 (6%)
Query: 24 PSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEH 83
P+ + G +C+ NG +Y G N + + G C W++ + + + + L E
Sbjct: 381 PNCDMSHGQDCYRGNGKNYMG--NLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNE- 437
Query: 84 NYCRNPDGDV-SPWCYVAEHEDGVYWKYCEIPACQ 117
NYCRNPD D PWCY + W YC I C+
Sbjct: 438 NYCRNPDDDAHGPWCYTG--NPLIPWDYCPISRCE 470
Score = 50.8 bits (120), Expect = 2e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 8/85 (9%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG-EHNYCRNPDGD 92
C G Y+GT + T + G C W+ H ++ L P+ G + NYCRNP G+
Sbjct: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSFL--PSSYRGKDLQENYCRNPRGE 183
Query: 93 V-SPWCYVAEHEDGVYWKYCEIPAC 116
PWC+ + E V ++ C+IP C
Sbjct: 184 EGGPWCFTSNPE--VRYEVCDIPQC 206
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 65.5 bits (158), Expect = 1e-10
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
+ CGG S + V+ SP FP +Y C W I +P H F F + D +E+
Sbjct: 1972 IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEI 2031
Query: 273 LDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK-EELPQ 329
+G +T ++ +F G P + + + +++F+SD QGF + YQA + + P
Sbjct: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHE-TLIHFYSDHSQNRQGFKLAYQAYELQNCPD 2090
Query: 330 ERPAVN 335
P N
Sbjct: 2091 PPPFQN 2096
Score = 61.6 bits (148), Expect = 1e-09
Identities = 63/242 (26%), Positives = 98/242 (40%), Gaps = 21/242 (8%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CG N ++ + +YSP FPD Y + C W I VP ++ +F L D + + DG
Sbjct: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVL-YQAVKEELPQERP 332
L F G + +++ S + V+L F SD N GF VL + A + + Q P
Sbjct: 2207 PDQNSPQLGVFSGNTALETAYS-STNQVLLKFHSDFSN--GGFFVLNFHAFQLKKCQPPP 2263
Query: 333 AVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGWTVYGLATLLILTVTAI 392
AV Q AE++TE + + HP T+ G + L
Sbjct: 2264 AVPQ--AEMLTEDDDFEIGD---------FVKYQCHPGYTLVGTDILTCKLSSQLQFEGS 2312
Query: 393 VAKILLHVTFKSHRVPASGDLRDCHQPG----TSGEIWSIFYKPSTSISIFKKKLKGQSQ 448
+ R +SG + PG + WSI +P+ +I+IF + + Q
Sbjct: 2313 LPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ 2372
Query: 449 QD 450
D
Sbjct: 2373 FD 2374
Score = 55.8 bits (133), Expect = 8e-08
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG Y+ VV SP++P Y G++C ++I VP + F F + D+ EL DG
Sbjct: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALN-DLAELFDG 1684
Query: 276 YTH---RVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
TH R+L+ G + + ++L F + A+GF +YQAV
Sbjct: 1685 -THAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 6/129 (4%)
Query: 203 DGRIILFDTLV---GACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFP 259
DG ++ T+ CGG+ +A S V+ P +P Y C W I I +F
Sbjct: 743 DGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFD 802
Query: 260 LFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFA 317
F + D +E+ DG + ++ +HG P + +F+ L F +D + GF
Sbjct: 803 RFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTG-NFMYLLFTTDNSRSSIGFL 861
Query: 318 VLYQAVKEE 326
+ Y++V E
Sbjct: 862 IHYESVTLE 870
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Query: 211 TLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMV 270
T + ACGGN + + V+ SP++P Y G+ C W ++V I F F++ S D +
Sbjct: 1447 TCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFL 1506
Query: 271 ELLDGY-THRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEE 326
+ +G ++ L + S+ P S + + L F SD GFA+ ++ E
Sbjct: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPRE 1563
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 3/110 (2%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
V +C N++A S ++ SP++P+ Y C W I S IH F FD+ D + +
Sbjct: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
Query: 273 LDGYTH--RVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLY 320
D VL F G + P S V L F SD +GF + Y
Sbjct: 642 KDDGISDITVLGTFSG-NEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
Score = 50.1 bits (118), Expect = 4e-06
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 3/111 (2%)
Query: 214 GACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELL 273
GACGG SS + SP FP Y C WTI I F F + + D +E+
Sbjct: 206 GACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEIS 265
Query: 274 DGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 324
+ P +S S +++ L+F SD ++ +GF +Q K
Sbjct: 266 GTEAPSIWLTGMNLPSPVIS---SKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Score = 49.7 bits (117), Expect = 6e-06
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
C GN++ + SP +P+ Y C W I V S I F + D +E+ DG
Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDG 1862
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
T L F G + P L N + + + L+F SD A GF + Y+ V
Sbjct: 1863 GDVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG + + SP FP Y C W I + I SF F + + D++ + DG
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
Query: 276 YTHR--VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
+ + R G + P S + + L+F +D AQGF LY+ +
Sbjct: 92 QPQQGNLKVRLSG-FQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVL 140
Score = 45.8 bits (107), Expect = 8e-05
Identities = 37/122 (30%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELL-D 274
CGG S V SP FPD Y C WTI V + F F + S D + + D
Sbjct: 931 CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITED 990
Query: 275 GYTHRVLARFHGRSRP-PLSFNVSLDFVI-LYFFSDRINQAQGFAVLYQAVKEELPQERP 332
G +AR G P + + +F L F SD +GF + + E P + P
Sbjct: 991 GSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLE-PCDDP 1049
Query: 333 AV 334
V
Sbjct: 1050 GV 1051
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 5/132 (3%)
Query: 194 GDHTQPC-GGDGRII--LFDTLVGACGGN-YSAMSSVVYSPDFPDTYATGRVCYWTIRVP 249
G +T C GD R+ + + CGG ++A S + SP +P Y C W I
Sbjct: 1253 GSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEAD 1312
Query: 250 GASHIHFSFPLFDIRDSADMVELLDG-YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSD 308
I F +FD + D++++ DG +L + S P + + + + L F SD
Sbjct: 1313 PGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSD 1372
Query: 309 RINQAQGFAVLY 320
GF++ +
Sbjct: 1373 FFISKSGFSIQF 1384
Score = 42.7 bits (99), Expect = 7e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASH-IHFSFPLFDIRDSADMVELLD 274
CG N S V+ SP++P Y C W I I +F F++ D + + D
Sbjct: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGD 471
Query: 275 ----GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKE 325
G T VL G S P L ++S + + L+ SD + GF +YQ +++
Sbjct: 472 AGKVGDTRSVLYVLTGSSVPDLIVSMS-NQMWLHLQSDDSIGSPGFKAVYQEIEK 525
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
Query: 224 SSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHR--VL 281
S V+ SP +P Y + C W+I+V +I F D +E+ DG + + +L
Sbjct: 2330 SGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLL 2389
Query: 282 ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQA 322
G +F + + L + +D +GF + Y A
Sbjct: 2390 VVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
Score = 40.8 bits (94), Expect = 0.003
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 200 CGGDGRIILFDTL---VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHF 256
C G GR + L V CG + + SP+FP Y C + I IH
Sbjct: 1086 CLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHL 1145
Query: 257 ---SFPLFDIRDSADMVELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRIN 311
SF LF+ D +++ DG + R L F L N + + + L F ++ +
Sbjct: 1146 RTRSFQLFE----GDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSD 1201
Query: 312 QAQGFAVLY 320
QGF + Y
Sbjct: 1202 TDQGFQLTY 1210
>gi|26051243 tumor necrosis factor, alpha-induced protein 6
precursor [Homo sapiens]
Length = 277
Score = 65.1 bits (157), Expect = 1e-10
Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 7/114 (6%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDS----ADMVE 271
CGG ++ + SP FP+ Y ++CYW IR+ IH SF FD+ D AD VE
Sbjct: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194
Query: 272 LLDGY--THRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
+ D Y H + R+ G P + + + L F SD A GF + Y A+
Sbjct: 195 IYDSYDDVHGFVGRYCGDELPDDIISTG-NVMTLKFLSDASVTAGGFQIKYVAM 247
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 63.2 bits (152), Expect = 5e-10
Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNET--FQHPYNTLKYPNGEGGLGEHNYCRNPDG 91
C+ NG YRG + + G+PCL WN Q Y+ + + GLG+HNYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTM--GRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDN 110
Query: 92 DVSPWCYV 99
PWCYV
Sbjct: 111 RRRPWCYV 118
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 63.2 bits (152), Expect = 5e-10
Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNET--FQHPYNTLKYPNGEGGLGEHNYCRNPDG 91
C+ NG YRG + + G+PCL WN Q Y+ + + GLG+HNYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTM--GRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDN 127
Query: 92 DVSPWCYV 99
PWCYV
Sbjct: 128 RRRPWCYV 135
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 63.2 bits (152), Expect = 5e-10
Identities = 35/111 (31%), Positives = 49/111 (44%), Gaps = 3/111 (2%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
+ CGG M V+ SP FP Y + C W I +P H F F + D +E+
Sbjct: 1965 IAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
Query: 273 LDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQ 321
+G T R++ RF G P + S + + YF SD GF + YQ
Sbjct: 2025 RNGPYETSRMMGRFSGSELPSSLLSTSHETTV-YFHSDHSQNRPGFKLEYQ 2074
Score = 59.7 bits (143), Expect = 5e-09
Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 211 TLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMV 270
T V CGGN + + SP FP+ Y C W I VP + I F + D +
Sbjct: 1791 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSL 1850
Query: 271 ELLDGYTHRV--LARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
E+ DG + V L F G + P L N + + + L+F+SD A GF + Y+ V
Sbjct: 1851 EVFDGADNTVTMLGSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
Score = 57.0 bits (136), Expect = 3e-08
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 9/156 (5%)
Query: 172 GNNPDYWKYG--EAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYS 229
G++ Y+ +G E T S G +P + R + CGG Y VV S
Sbjct: 1577 GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC----TAPCGGQYVGSDGVVLS 1632
Query: 230 PDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTH--RVLARFHGR 287
P++P Y +G++C + + VP + F F + D+VE+ DG++ R+L+ G
Sbjct: 1633 PNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-DVVEVHDGHSQHSRLLSSLSGS 1691
Query: 288 SRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
+ + V++ F + + A+GF +YQAV
Sbjct: 1692 HTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 6/137 (4%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGGN ++ + VYSP FP Y++ + C W I VP + + L S D + + DG
Sbjct: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDG 2241
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERPA 333
T L F RS + S + V+L F D FA+ + A L + P
Sbjct: 2242 PQQTAPRLGVF-TRSMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAY--PLTKCPPP 2297
Query: 334 VNQTVAEVITEQANLSV 350
AEV+TE ++
Sbjct: 2298 TILPNAEVVTENEEFNI 2314
Score = 53.5 bits (127), Expect = 4e-07
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 3/112 (2%)
Query: 211 TLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMV 270
T + CGG+ + S V+ SP++P+ Y G+ C W + V I F +F++ D +
Sbjct: 1440 TCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFL 1499
Query: 271 ELLDG--YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLY 320
+ DG ++ F+G S+ P S + + L F SD GF + Y
Sbjct: 1500 HIYDGRDSLSPLIGSFYG-SQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
Score = 52.4 bits (124), Expect = 9e-07
Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 215 ACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD 274
ACGG S ++ SP FP Y C WTI I F F + D D +E+
Sbjct: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTG 260
Query: 275 GYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKE 325
T F G S P + S +++ L+F SD ++ +GF+ YQ K+
Sbjct: 261 --TEGSSLWFTGASLPAPVIS-SKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
Score = 52.4 bits (124), Expect = 9e-07
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 4/126 (3%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
V +C N+++ S VV SP++P+ Y C W I S IH +F D+ D + +
Sbjct: 575 VFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
Query: 273 LDGYTHR--VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK-EELPQ 329
DG T VL F G ++ P S S L F +D +GF + + + E P
Sbjct: 635 KDGATAEAPVLGTFSG-NQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPD 693
Query: 330 ERPAVN 335
VN
Sbjct: 694 PGVPVN 699
Score = 52.4 bits (124), Expect = 9e-07
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG 275
CGG+ ++ S + SP +P Y C W I I +F F + D +E+ DG
Sbjct: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDG 811
Query: 276 --YTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
Y+ ++ +HG P + S +++ L F +D+ + GF + Y+ +
Sbjct: 812 RTYSAPLIGVYHGTQVPQFLISTS-NYLYLLFSTDKSHSDIGFQLRYETI 860
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 2/112 (1%)
Query: 211 TLVGACGGNYSA-MSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADM 269
T V CGG +S V SP +P Y C WTI I F +FD + D+
Sbjct: 1266 TCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDV 1325
Query: 270 VELLDGYTHR-VLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLY 320
+ + DG VL + P + + + V+L F +D QGFA+ +
Sbjct: 1326 LRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 1377
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 4/122 (3%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLD- 274
CGG S + SP FPD Y C W I + F+F F + D + + +
Sbjct: 924 CGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITEN 983
Query: 275 GYTHRVLARFHGRSRP-PLSFNVSLDFVI-LYFFSDRINQAQGFAVLYQAVKEELPQERP 332
G + L + G P P+S + +F + F SD +GF + + E P E P
Sbjct: 984 GSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLE-PCEEP 1042
Query: 333 AV 334
V
Sbjct: 1043 EV 1044
Score = 42.7 bits (99), Expect = 7e-04
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
Query: 224 SSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHR--VL 281
+ V+ S +P +Y + C W +RV +I + F D E+ DG + + +L
Sbjct: 2365 TGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLL 2424
Query: 282 ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQ 329
G PL S + V L + SD +GF + Y A LP+
Sbjct: 2425 KALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPR 2472
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/112 (22%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 213 VGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVEL 272
V CG + + + SP+FP Y C ++I+ I F++ + D++++
Sbjct: 1095 VAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSE-GDVLKV 1153
Query: 273 LDGYTH--RVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQA 322
DG + R+L F ++ N + + L F +D N ++GF + + +
Sbjct: 1154 YDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
Score = 37.7 bits (86), Expect = 0.022
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 6/115 (5%)
Query: 216 CGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASH-IHFSFPLFDIRDSADMVEL-- 272
C + S ++ SP+FP Y C W I S I +F FD+ D + +
Sbjct: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGD 464
Query: 273 --LDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKE 325
DG VL G S P L + + +L F +D + GF Y+ +++
Sbjct: 465 GGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLL-FQTDGSGSSLGFKASYEEIEQ 518
Score = 37.0 bits (84), Expect = 0.037
Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Query: 224 SSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDG--YTHRVL 281
+ V SP FP Y C WTI I F F + + D++ + DG +
Sbjct: 34 NGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDGPPQPENLR 93
Query: 282 ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAV 323
R G P + + + L SD AQGF Y+ +
Sbjct: 94 TRLTGFQLPATIVSAATT-LSLRLISDYAVSAQGFHATYEVL 134
>gi|134152686 receptor tyrosine kinase-like orphan receptor 1
isoform 2 [Homo sapiens]
Length = 393
Score = 62.0 bits (149), Expect = 1e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETF--QHPYNTLKYPNGEGGLGEHNYCRNPD 90
+C+ + G DYRGT + T + G+ C WN + H + L++P GG H+YCRNP
Sbjct: 312 KCYNSTGVDYRGTVSVT--KSGRQCQPWNSQYPHTHTFTALRFPELNGG---HSYCRNPG 366
Query: 91 GD-VSPWCYVAEHEDGVYWKYCEIPAC 116
+PWC+ ++ C+IPAC
Sbjct: 367 NQKEAPWCFTL--DENFKSDLCDIPAC 391
>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
isoform 1 [Homo sapiens]
Length = 937
Score = 62.0 bits (149), Expect = 1e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETF--QHPYNTLKYPNGEGGLGEHNYCRNPD 90
+C+ + G DYRGT + T + G+ C WN + H + L++P GG H+YCRNP
Sbjct: 312 KCYNSTGVDYRGTVSVT--KSGRQCQPWNSQYPHTHTFTALRFPELNGG---HSYCRNPG 366
Query: 91 GD-VSPWCYVAEHEDGVYWKYCEIPAC 116
+PWC+ ++ C+IPAC
Sbjct: 367 NQKEAPWCFTL--DENFKSDLCDIPAC 391
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 61.6 bits (148), Expect = 1e-09
Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 18/117 (15%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWN--ETFQHPYNTLKYPNGEGGLGEHNYCRNPDG 91
C NG +YRG + T + G+ C W+ QHP+ K+ + GL + NYCRNPDG
Sbjct: 205 CVWCNGEEYRGAVDRT--ESGRECQRWDLQHPHQHPFEPGKFL--DQGLDD-NYCRNPDG 259
Query: 92 DVSPWCYVAEHEDGVYWKYCEIPAC-------QMPGNLGCYKDHGNPPPLTGTSKTS 141
PWCY + + + ++C++P C Q + C++ G GT+ T+
Sbjct: 260 SERPWCYTTDPQ--IEREFCDLPRCGSEAQPRQEATTVSCFRGKGE--GYRGTANTT 312
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/93 (39%), Positives = 47/93 (50%), Gaps = 10/93 (10%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKY-PNGEGGLGEHNYCRNPDGD 92
C NG YRGT T GG PC W+ F + + KY P GL E N+CRNPDGD
Sbjct: 124 CIMNNGVGYRGTMATTV--GGLPCQAWSHKFPNDH---KYTPTLRNGL-EENFCRNPDGD 177
Query: 93 V-SPWCYVAEHEDGVYWKYCEIPACQMPGNLGC 124
PWCY + V ++ C I +C+ + C
Sbjct: 178 PGGPWCYTT--DPAVRFQSCGIKSCREAACVWC 208
Score = 52.8 bits (125), Expect = 7e-07
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDV 93
CF G YRGT N T G PC W+ H + L E N+CRNPDG
Sbjct: 297 CFRGKGEGYRGTANTTT--AGVPCQRWDAQIPHQHRFTPEKYACKDLRE-NFCRNPDGSE 353
Query: 94 SPWCY 98
+PWC+
Sbjct: 354 APWCF 358
Score = 46.6 bits (109), Expect = 5e-05
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 8/86 (9%)
Query: 33 ECFTANGADYRGTQNWTALQGGKPCLFWN-ETFQHPYNTLKYPNGEGGLGEHNYCRNPDG 91
+C+ G YRGT + T + G C W+ ET P T + + E N+CRNPDG
Sbjct: 383 DCYHGAGEQYRGTVSKT--RKGVQCQRWSAETPHKPQFT--FTSEPHAQLEENFCRNPDG 438
Query: 92 DV-SPWCYVAEHEDGVYWKYCEIPAC 116
D PWCY + + YC + C
Sbjct: 439 DSHGPWCYTMDPR--TPFDYCALRRC 462
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 60.1 bits (144), Expect = 4e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 14/98 (14%)
Query: 24 PSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPY----NTLKYPNGEGG 79
P+ LG +C+ +G DYRGT + T + G C W QHP+ ++ +P GG
Sbjct: 306 PAERLGRYHQCYNGSGMDYRGTASTT--KSGHQCQPW--ALQHPHSHHLSSTDFPELGGG 361
Query: 80 LGEHNYCRNPDGDV-SPWCYVAEHEDGVYWKYCEIPAC 116
H YCRNP G + PWC+ V + C++P+C
Sbjct: 362 ---HAYCRNPGGQMEGPWCFT--QNKNVRMELCDVPSC 394
>gi|54792094 WSC domain containing 1 [Homo sapiens]
Length = 575
Score = 53.5 bits (127), Expect = 4e-07
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 114 PACQMPGN-LGCYKDHGNPPPLTGTSKTS-NKLTIQTCISFCRSQRFKFAGMESGYACFC 171
PA G +GC+ D G+ L G K+T+ C C + + +AG+E+G C+C
Sbjct: 137 PAIHSRGTYIGCFSDDGHERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYC 196
Query: 172 GNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILF 209
GN G ECN C G+ CG R+ ++
Sbjct: 197 GNRLPAVSVG---LEECNHECKGEKGSVCGAVDRLSVY 231
Score = 29.3 bits (64), Expect = 7.8
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 123 GCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFC 171
GC++ N +S +T+ TC FC + F A + G+ C+C
Sbjct: 250 GCFRLPENITHAFPSSLIQANVTVGTCSGFCSQKEFPLAILR-GWECYC 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,760,501
Number of Sequences: 37866
Number of extensions: 1044698
Number of successful extensions: 3379
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3012
Number of HSP's gapped (non-prelim): 315
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.