Search of human proteins with 226693363

Search of human proteins with 226693363

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226693363 phospholipase A2, group IVC isoform 3 [Homo
sapiens]
         (527 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]    1072   0.0  
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho...  1072   0.0  
gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho...  1049   0.0  
gi|67972429 phospholipase A2, group IVF [Homo sapiens]                195   7e-50
gi|116174754 phospholipase A2, group IVD [Homo sapiens]               179   4e-45
gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]      167   3e-41
gi|167860120 phospholipase A2, group IVB [Homo sapiens]               165   8e-41
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]                       165   8e-41
gi|122937428 phospholipase A2, group 4E [Homo sapiens]                154   2e-37
gi|24308237 phosphatidylinositol transfer protein, membrane-asso...    33   0.84 
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    32   1.1  
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    32   1.1  
gi|254281232 zinc finger and SCAN domain containing 12 [Homo sap...    29   9.3  
gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Ho...    29   9.3  
gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]          29   9.3  

>gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]
          Length = 527

 Score = 1072 bits (2773), Expect = 0.0
 Identities = 527/527 (100%), Positives = 527/527 (100%)

Query: 1   MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL 60
           MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL
Sbjct: 1   MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL 60

Query: 61  GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL 120
           GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL
Sbjct: 61  GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL 120

Query: 121 QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ 180
           QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ
Sbjct: 121 QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ 180

Query: 181 PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG 240
           PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG
Sbjct: 181 PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG 240

Query: 241 SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED 300
           SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED
Sbjct: 241 SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED 300

Query: 301 EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT 360
           EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT
Sbjct: 301 EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT 360

Query: 361 HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET 420
           HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET
Sbjct: 361 HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET 420

Query: 421 IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE 480
           IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE
Sbjct: 421 IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE 480

Query: 481 AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 527
           AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG
Sbjct: 481 AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 527


>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
           sapiens]
          Length = 541

 Score = 1072 bits (2773), Expect = 0.0
 Identities = 527/527 (100%), Positives = 527/527 (100%)

Query: 1   MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL 60
           MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL
Sbjct: 1   MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL 60

Query: 61  GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL 120
           GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL
Sbjct: 61  GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL 120

Query: 121 QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ 180
           QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ
Sbjct: 121 QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ 180

Query: 181 PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG 240
           PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG
Sbjct: 181 PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG 240

Query: 241 SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED 300
           SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED
Sbjct: 241 SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED 300

Query: 301 EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT 360
           EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT
Sbjct: 301 EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT 360

Query: 361 HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET 420
           HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET
Sbjct: 361 HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET 420

Query: 421 IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE 480
           IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE
Sbjct: 421 IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE 480

Query: 481 AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 527
           AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG
Sbjct: 481 AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 527


>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
           sapiens]
          Length = 551

 Score = 1049 bits (2712), Expect = 0.0
 Identities = 514/515 (99%), Positives = 515/515 (100%)

Query: 13  QKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL 72
           +KEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL
Sbjct: 23  KKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL 82

Query: 73  DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY 132
           DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY
Sbjct: 83  DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY 142

Query: 133 SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW 192
           SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW
Sbjct: 143 SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW 202

Query: 193 FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY 252
           FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY
Sbjct: 203 FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY 262

Query: 253 IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE 312
           IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE
Sbjct: 263 IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE 322

Query: 313 MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD 372
           MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD
Sbjct: 323 MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD 382

Query: 373 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK 432
           KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK
Sbjct: 383 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK 442

Query: 433 IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA 492
           IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA
Sbjct: 443 IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA 502

Query: 493 DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 527
           DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG
Sbjct: 503 DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 537


>gi|67972429 phospholipase A2, group IVF [Homo sapiens]
          Length = 849

 Score =  195 bits (496), Expect = 7e-50
 Identities = 158/509 (31%), Positives = 233/509 (45%), Gaps = 86/509 (16%)

Query: 1   MGSSEVSIIPG--LQKEEKAAVERRRLHVLKALKKL-----RIEADEAPVVAVLGSGGGL 53
           M S ++ +  G  L   E+  ++RR+  V KAL+++      +++ + PVVAVLGSGGG 
Sbjct: 307 MSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVLGSGGGT 366

Query: 54  RAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQE 113
           RA  +  G L+ ++E GLLD VTYL+GVSGSTW IS+LY    D    +  L+    R +
Sbjct: 367 RAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYR---DPAWSQVALQGPIERAQ 423

Query: 114 WDLAKSLQKTIQAARSENY--------------SLTDFWAYMVISKQTRELPESHLSNMK 159
             +  S    +   R + Y              SL D W  +V     +E   + LS+ +
Sbjct: 424 VHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENPAKLSDQQ 483

Query: 160 KPVEEGTLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFK 219
           + V +G  PYPI+ +++     S ++      W EFTP+  GF   GA+V    FGS+  
Sbjct: 484 EAVRQGQNPYPIYTSVNVRTNLSGEDF---AEWCEFTPYEVGFPKYGAYVPTELFGSELF 540

Query: 220 KGRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGL-WRRAVANAKSIGH 278
            GRL++  PE  + +L+G+WGSA   +    + IF +     L  L W R   N      
Sbjct: 541 MGRLLQLQPEPRICYLQGMWGSAFATS---LDEIFLKTAGSGLSFLEWYRGSVNI----- 592

Query: 279 LIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTEMLENWT--RTSLEKQEQPHEDPER-- 334
                                D+  +P+       L N +  RT L   + P        
Sbjct: 593 --------------------TDDCQKPQ-------LHNPSRLRTRLLTPQGPFSQAVLDI 625

Query: 335 -KGSLSNLMDFVKKTGICASK--------WEWGTTHNFLYKHGGIRDKIMSSRKHLHLVD 385
                ++   F    G+C  K          W  TH   +      +++   R  L+LVD
Sbjct: 626 FTSRFTSAQSFNFTRGLCLHKDYVAGREFVAWKDTHPDAFP-----NQLTPMRDCLYLVD 680

Query: 386 AGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDL 445
            G AIN+PFPL L P R V LILSFD+S   PFE ++ T  YC    IPFP +E    D+
Sbjct: 681 GGFAINSPFPLALLPQRAVDLILSFDYSLEAPFEVLKMTEKYCLDRGIPFPSIEVGPEDV 740

Query: 446 WSKAPASCYIL---KGETGPVVMHFPLFN 471
             +    CY+    +    P+V+HFPL N
Sbjct: 741 --EEARECYLFAKAEDPRSPIVLHFPLVN 767


>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
          Length = 818

 Score =  179 bits (455), Expect = 4e-45
 Identities = 153/548 (27%), Positives = 240/548 (43%), Gaps = 76/548 (13%)

Query: 15  EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
           EE+A + RR+  V KALK+       ++ DE PVV ++ +GGG RA  +  G L  +++ 
Sbjct: 289 EEQAFLSRRKQVVAKALKQALQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKL 348

Query: 70  GLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARS 129
           GLLD VTY +G+SGSTW ++ LY   GD E  + DL+         LAKS  +     R 
Sbjct: 349 GLLDCVTYFSGISGSTWTMAHLY---GDPEWSQRDLEGPIRYAREHLAKSKLEVFSPERL 405

Query: 130 ENY--------------SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAI 175
            +Y              +  D WA ++ S    ++ +  LS  +  +E G  P P++ ++
Sbjct: 406 ASYRRELELRAEQGHPTTFVDLWALVLESMLHGQVMDQKLSGQRAALERGQNPLPLYLSL 465

Query: 176 DNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFL 235
             +++ +  E    + W EF+P+  GF   GAFV    FGS+F  GRL+R  PE  + FL
Sbjct: 466 --NVKENNLETLDFKEWVEFSPYEVGFLKYGAFVPPELFGSEFFMGRLMRRIPEPRICFL 523

Query: 236 RGLWGSALGNTEVIREYIFDQLRNLTLKG-LWRRAVANAKSIGHLIFARLLRLQESSQGE 294
             +W      + +    + D   +LT  G  W++ + +                 S + E
Sbjct: 524 EAIW------SNIFSLNLLDAWYDLTSSGESWKQHIKDK--------------TRSLEKE 563

Query: 295 HPPPEDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICA 352
                      E +WL     L    +  L  +      P     L    D+      C+
Sbjct: 564 PLTTSGTSSRLEASWLQPGTALAQAFKGFLTGRPLHQRSPNFLQGLQLHQDY------CS 617

Query: 353 SKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDF 412
            K ++ T  +  Y+   +  ++      L LVDA   INT  P +  P R + LILSFD+
Sbjct: 618 HK-DFSTWAD--YQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMFRPGRRLDLILSFDY 674

Query: 413 SAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGET---GPVVMHFPL 469
           S   PFE ++ T  YCR   +PFP+VE +  D     P  C++         P+++HFPL
Sbjct: 675 SLSAPFEALQQTELYCRARGLPFPRVEPSPQD--QHQPRECHLFSDPACPEAPILLHFPL 732

Query: 470 FN---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVREN 514
            N                +  GG ++    T        TY  +    LL L+  NV+ +
Sbjct: 733 VNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFERLLRLSDYNVQTS 792

Query: 515 KKKILREL 522
           +  IL+ L
Sbjct: 793 QGAILQAL 800


>gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]
          Length = 749

 Score =  167 bits (422), Expect = 3e-41
 Identities = 140/516 (27%), Positives = 237/516 (45%), Gaps = 79/516 (15%)

Query: 15  EEKAAVERRRLHVLKALKKLR--------IEADEAPVVAVLGSGGGLRAHIACLGVLSEM 66
           +EK   ++R+ H+ +++KKL           A + PVVA+LGSGGG RA +   GV+  +
Sbjct: 153 QEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKAL 212

Query: 67  KEQGLLDAVTYLAGVSGSTWAISSLYTN--------DGDMEALEADLKHR----FTRQEW 114
            E G+LD  TY+AG+SGSTW +S+LY++        +   E L  ++ H      T Q+ 
Sbjct: 213 YESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKV 272

Query: 115 D-LAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFA 173
               +SL K  + +  +  + TD +  ++          + LS++K+ V     P P+F 
Sbjct: 273 KRYVESLWK--KKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFT 330

Query: 174 AIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLT 233
            +   ++P   E    + W EF+P+  G +  G F++   FGSKF  G +V+ + E  L 
Sbjct: 331 CL--HVKPDVSELMFAD-WVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLH 387

Query: 234 FLRGLWGSA----------LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFAR 283
           FL G+WGSA          +  ++     + ++L N+T K +    V+N  S        
Sbjct: 388 FLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHI----VSNDSSDSD----- 438

Query: 284 LLRLQESSQGEHPPPEDEG----GEPEHTWLTEML------ENWTRTSLEKQEQPHE--- 330
                ES + +    ED G     + + +W+  M+           T   +  + H    
Sbjct: 439 ----DESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFML 494

Query: 331 --DPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGL 388
             +      LS L DF  +      + +        ++   I + +    K +H+VD+GL
Sbjct: 495 GLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFER--IYEPLDVKSKKIHVVDSGL 552

Query: 389 AINTPFPLVLPPTREVHLILSFDFSA-----GDPFETIRATTDYCRRHKIPFPQVEEAEL 443
             N P+PL+L P R V LI+SFDFSA       PF+ +     + + +K+PFP+++    
Sbjct: 553 TFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVF 612

Query: 444 DLWSKAPASCYILKGETG------PVVMHFPLFNID 473
           D   +    CY+ K +        P ++HF L NI+
Sbjct: 613 D--REGLKECYVFKPKNPDMEKDCPTIIHFVLANIN 646


>gi|167860120 phospholipase A2, group IVB [Homo sapiens]
          Length = 781

 Score =  165 bits (418), Expect = 8e-41
 Identities = 153/550 (27%), Positives = 243/550 (44%), Gaps = 86/550 (15%)

Query: 15  EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
           EE+A + RR+  V  AL++       ++ DE PVVA++ +GGG+RA  +  G L+ +KE 
Sbjct: 263 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 322

Query: 70  GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 119
           GLLD V+Y+ G SGSTWA+++LY     +  D+      LK + T+ +        L + 
Sbjct: 323 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 382

Query: 120 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 177
            Q+  + AR    S  T+ WA ++      + P  H LS+ ++ +  G  P PI+ A++ 
Sbjct: 383 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 441

Query: 178 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 237
             Q S       E W EF+P+  GF   GAF+    FGS+F  G+L++  PE  + FL G
Sbjct: 442 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 499

Query: 238 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 297
           +W +       +++ ++           W R  AN           LL+++E       P
Sbjct: 500 IWSNLYAAN--LQDSLYWASEPSQFWDRWVRNQANLDKEQ----VPLLKIEE-------P 546

Query: 298 PEDEGGEPEH-----TW--LTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI 350
           P   G   E      TW  L +   N+ R  L   +   + P                  
Sbjct: 547 PSTAGRIAEFFTDLLTWRPLAQATHNFLR-GLHFHKDYFQHPH----------------- 588

Query: 351 CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF 410
             S W+  T         G+ +++  S  HL L+D G  INT    +L PTR+V LILS 
Sbjct: 589 -FSTWKATTL-------DGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSL 640

Query: 411 DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGET---GPVVMHF 467
           D++    F+ ++    +C+   IPFP +  +  +     P  C+     T    P V+HF
Sbjct: 641 DYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPRECHTFSDPTCPGAPAVLHF 698

Query: 468 PLFN---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVR 512
           PL +                +A  G++   S          TY+ + V  LL L   NV 
Sbjct: 699 PLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVC 758

Query: 513 ENKKKILREL 522
            N++++L  L
Sbjct: 759 NNQEQLLEAL 768


>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
          Length = 1012

 Score =  165 bits (418), Expect = 8e-41
 Identities = 153/550 (27%), Positives = 243/550 (44%), Gaps = 86/550 (15%)

Query: 15  EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
           EE+A + RR+  V  AL++       ++ DE PVVA++ +GGG+RA  +  G L+ +KE 
Sbjct: 494 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 553

Query: 70  GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 119
           GLLD V+Y+ G SGSTWA+++LY     +  D+      LK + T+ +        L + 
Sbjct: 554 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 613

Query: 120 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 177
            Q+  + AR    S  T+ WA ++      + P  H LS+ ++ +  G  P PI+ A++ 
Sbjct: 614 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 672

Query: 178 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 237
             Q S       E W EF+P+  GF   GAF+    FGS+F  G+L++  PE  + FL G
Sbjct: 673 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 730

Query: 238 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 297
           +W +       +++ ++           W R  AN           LL+++E       P
Sbjct: 731 IWSNLYAAN--LQDSLYWASEPSQFWDRWVRNQANLDKEQ----VPLLKIEE-------P 777

Query: 298 PEDEGGEPEH-----TW--LTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI 350
           P   G   E      TW  L +   N+ R  L   +   + P                  
Sbjct: 778 PSTAGRIAEFFTDLLTWRPLAQATHNFLR-GLHFHKDYFQHPH----------------- 819

Query: 351 CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF 410
             S W+  T         G+ +++  S  HL L+D G  INT    +L PTR+V LILS 
Sbjct: 820 -FSTWKATTL-------DGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSL 871

Query: 411 DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGET---GPVVMHF 467
           D++    F+ ++    +C+   IPFP +  +  +     P  C+     T    P V+HF
Sbjct: 872 DYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPRECHTFSDPTCPGAPAVLHF 929

Query: 468 PLFN---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVR 512
           PL +                +A  G++   S          TY+ + V  LL L   NV 
Sbjct: 930 PLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVC 989

Query: 513 ENKKKILREL 522
            N++++L  L
Sbjct: 990 NNQEQLLEAL 999


>gi|122937428 phospholipase A2, group 4E [Homo sapiens]
          Length = 839

 Score =  154 bits (389), Expect = 2e-37
 Identities = 141/546 (25%), Positives = 237/546 (43%), Gaps = 81/546 (14%)

Query: 20  VERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDA 74
           +++R++ V KALK++      ++ DE P++A++ +GGG R+  +  G L  +++  LLD 
Sbjct: 316 LQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDC 375

Query: 75  VTYLAGVSGSTWAISSLYTNDGD----------MEALEADLKHRFTRQEWDLAKSLQKTI 124
            +Y+ G+SG+TW +++LY  D D           EA    +K +      D  +  Q+ +
Sbjct: 376 ASYITGLSGATWTMATLY-RDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEEL 434

Query: 125 QAARSENY--SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPS 182
           +    E Y  + TDFW  ++ +    E  E  LS+ +  +  G  P PI+  I+     S
Sbjct: 435 RQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVS 494

Query: 183 WQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSA 242
            Q+ R    WFEF+P+  G    GAF+    FGS+F  GRLV+  PE  + ++ GLW S 
Sbjct: 495 NQDFR---EWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSS- 550

Query: 243 LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHP----PP 298
                         + +L L   W     N        F R  R +     + P     P
Sbjct: 551 --------------IFSLNLLDAW-----NLSHTSEEFFHRWTREKVQDIEDEPILPEIP 591

Query: 299 EDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWE 356
           + +    E T +     L N  R  L  +    E       L    ++++      S+W+
Sbjct: 592 KCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQF--SRWK 649

Query: 357 WGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGD 416
                 F        +++  S  HL L+D    +N+ +P +L P R+  LI+  ++ AG 
Sbjct: 650 DTVLDGF-------PNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGS 702

Query: 417 PFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG---ETGPVVMHFPLFN-- 471
             + ++ T +YC    IPFP+    EL   ++    CY+++       P+V  FPL N  
Sbjct: 703 QTKPLKQTCEYCTVQNIPFPKY---ELPDENENLKECYLMENPQEPDAPIVTFFPLINDT 759

Query: 472 ---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKK 516
                          ++    DI      Y T +L  TYT      L+ L++ N+  NK 
Sbjct: 760 FRKYKAPGVERSPEELEQGQVDIYGPKTPYATKEL--TYTEATFDKLVKLSEYNILNNKD 817

Query: 517 KILREL 522
            +L+ L
Sbjct: 818 TLLQAL 823


>gi|24308237 phosphatidylinositol transfer protein,
           membrane-associated 2 [Homo sapiens]
          Length = 1349

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 36/172 (20%), Positives = 63/172 (36%), Gaps = 46/172 (26%)

Query: 287 LQESSQGEHPPPEDEGGEP------EHTWLT----------------EMLENWTRTSLEK 324
           + + + GE P P    GEP      +  W T                  +  W   S+ +
Sbjct: 276 VSDQTSGEPPEPSSSNGEPLVGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIAR 335

Query: 325 QEQPHEDPERKGSLSNLMDFVKKTGICASKW------------EWGTTHNFLYKHGGIRD 372
                 D E   +  +L D  +      +KW            E   T + LY+ G    
Sbjct: 336 DSDESSDDEFFDAHEDLSDTEEMFPKDITKWSSNDLMDKIESPEPEDTQDGLYRQGAPEF 395

Query: 373 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLIL-------SFDFSAGDP 417
           ++ SS + L++++  ++     PL  PP++ +H++L         D  AGDP
Sbjct: 396 RVASSVEQLNIIEDEVS----QPLAAPPSK-IHVLLLVLHGGTILDTGAGDP 442


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
            sapiens]
          Length = 1591

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 17/141 (12%)

Query: 7    SIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEM 66
            +II  L+K+ +  V  +     + ++KL  E DEA           ++  +    +  E+
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEA-----------IQTALKEFKLEREV 1255

Query: 67   KEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQA 126
             E+ LL+ V +L      + AI S     GD  +L A+L+ +   ++   AK L++  + 
Sbjct: 1256 VEKELLEKVKHLENQIAKSPAIDS---TRGDSSSLVAELQEKLQEEK---AKFLEQLEEQ 1309

Query: 127  ARSENYSLTDFWAYMVISKQT 147
             + +N  + +    ++  +QT
Sbjct: 1310 EKRKNEEMQNVRTSLIAEQQT 1330


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
            sapiens]
          Length = 1594

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 17/141 (12%)

Query: 7    SIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEM 66
            +II  L+K+ +  V  +     + ++KL  E DEA           ++  +    +  E+
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEA-----------IQTALKEFKLEREV 1255

Query: 67   KEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQA 126
             E+ LL+ V +L      + AI S     GD  +L A+L+ +   ++   AK L++  + 
Sbjct: 1256 VEKELLEKVKHLENQIAKSPAIDS---TRGDSSSLVAELQEKLQEEK---AKFLEQLEEQ 1309

Query: 127  ARSENYSLTDFWAYMVISKQT 147
             + +N  + +    ++  +QT
Sbjct: 1310 EKRKNEEMQNVRTSLIAEQQT 1330


>gi|254281232 zinc finger and SCAN domain containing 12 [Homo
           sapiens]
          Length = 611

 Score = 29.3 bits (64), Expect = 9.3
 Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)

Query: 84  STWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKS 119
           STWAI +    D  +E    + K+  TRQ+WDL K+
Sbjct: 3   STWAIQAHMDQDEPLEVKIEEEKYT-TRQDWDLRKN 37


>gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Homo
           sapiens]
          Length = 411

 Score = 29.3 bits (64), Expect = 9.3
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 288 QESSQGEHPPPEDEGGEP---EHTWLTEMLENWTRTSLEKQEQPHEDPERKGSL--SNLM 342
           QE    E PPP D GG+    + T      E+ T  S+E+ E+   D E K ++  ++L+
Sbjct: 238 QEEHAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLV 297

Query: 343 DFVKKTGI-CASKWEWGTTHN-FLYKHGGIRDKI 374
                 G  C ++ E     N FL K+  +R K+
Sbjct: 298 VLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKV 331


>gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]
          Length = 992

 Score = 29.3 bits (64), Expect = 9.3
 Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 8/109 (7%)

Query: 221 GRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLI 280
           GR++  H ER L  L+ L G  + N      Y   + + L+      R    A      +
Sbjct: 798 GRIMEDHEERKLQHLKTLQGERMEN------YKLRKKQELSNPSSGSRTAGGAHETSQAV 851

Query: 281 FARLLRLQESSQGEHPPPEDE--GGEPEHTWLTEMLENWTRTSLEKQEQ 327
             R+L  Q+    + P  +      + +   + ++LE    T L++ EQ
Sbjct: 852 HQRMLSQQKRFLAQFPVHQQMRLHAQQQQAGVMDLLEAQLETQLQEAEQ 900


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,271,242
Number of Sequences: 37866
Number of extensions: 1002555
Number of successful extensions: 2626
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2584
Number of HSP's gapped (non-prelim): 23
length of query: 527
length of database: 18,247,518
effective HSP length: 107
effective length of query: 420
effective length of database: 14,195,856
effective search space: 5962259520
effective search space used: 5962259520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.