Guide to the Human Genome
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Search of human proteins with 226371743

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type
II, gamma isoform c [Homo sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,...   755   0.0  
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,...   733   0.0  
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,...   733   0.0  
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,...   682   0.0  
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b...   463   e-130
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a...   459   e-129
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g...   139   3e-33
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be...   135   6e-32
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   132   4e-31
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   132   4e-31
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al...   132   4e-31
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   107   1e-23
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is...    82   8e-16
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso...    65   8e-11
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    49   7e-06
gi|6005997 double C2-like domains, beta [Homo sapiens]                 33   0.54 
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            32   0.92 
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]          30   2.7  
gi|29789078 UDP glycosyltransferase 1 family, polypeptide A10 pr...    30   2.7  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    30   3.5  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    30   3.5  
gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo sapi...    30   3.5  
gi|117553613 coiled-coil domain containing 151 [Homo sapiens]          30   3.5  
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa...    30   4.6  
gi|4758220 XAP-5 protein [Homo sapiens]                                29   6.0  
gi|145580615 KRI1 homolog [Homo sapiens]                               29   6.0  
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  29   6.0  
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        29   7.8  

>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform c [Homo sapiens]
          Length = 373

 Score =  755 bits (1950), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120

Query: 121 DYLYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREA 180
           DYLYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREA
Sbjct: 121 DYLYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREA 180

Query: 181 SDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIH 240
           SDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIH
Sbjct: 181 SDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIH 240

Query: 241 DIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFE 300
           DIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFE
Sbjct: 241 DIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFE 300

Query: 301 SFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQY 360
           SFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQY
Sbjct: 301 SFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQY 360

Query: 361 AKRFLDFITNIFA 373
           AKRFLDFITNIFA
Sbjct: 361 AKRFLDFITNIFA 373


>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score =  733 bits (1891), Expect = 0.0
 Identities = 373/421 (88%), Positives = 373/421 (88%), Gaps = 48/421 (11%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120

Query: 121 DYL------------------------------------------------YIVKCHGNT 132
           DYL                                                YIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180

Query: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 192
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240

Query: 193 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 252
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300

Query: 253 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 312
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360

Query: 313 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 372
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420

Query: 373 A 373
           A
Sbjct: 421 A 421


>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score =  733 bits (1891), Expect = 0.0
 Identities = 373/421 (88%), Positives = 373/421 (88%), Gaps = 48/421 (11%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120

Query: 121 DYL------------------------------------------------YIVKCHGNT 132
           DYL                                                YIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180

Query: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 192
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240

Query: 193 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 252
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300

Query: 253 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 312
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360

Query: 313 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 372
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420

Query: 373 A 373
           A
Sbjct: 421 A 421


>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform b [Homo sapiens]
          Length = 403

 Score =  682 bits (1759), Expect = 0.0
 Identities = 355/421 (84%), Positives = 355/421 (84%), Gaps = 66/421 (15%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIK                  EYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIK------------------EYCPQVFRNLRDRFGIDDQ 102

Query: 121 DYL------------------------------------------------YIVKCHGNT 132
           DYL                                                YIVKCHGNT
Sbjct: 103 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 162

Query: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 192
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 222

Query: 193 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 252
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 223 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 282

Query: 253 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 312
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 283 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 342

Query: 313 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 372
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 343 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 402

Query: 373 A 373
           A
Sbjct: 403 A 403


>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
           [Homo sapiens]
          Length = 416

 Score =  463 bits (1192), Expect = e-130
 Identities = 238/397 (59%), Positives = 287/397 (72%), Gaps = 54/397 (13%)

Query: 26  SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
           +KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIKV+
Sbjct: 21  TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80

Query: 86  NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYL---------------------- 123
           NHLF++ENLPS FKFKEYCP VFRNLR+RFGIDDQDY                       
Sbjct: 81  NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140

Query: 124 -----------------------------YIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 154
                                        +IV+CHGNTLLPQFLGMYR++VD  ++YM+V
Sbjct: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200

Query: 155 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 214
            RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260

Query: 215 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 274
           LEKLKRDVEFL QLKIMDYSLL+GIHD+ R  + E E   R ++ E + D  + G   L+
Sbjct: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317

Query: 275 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 334
            SYGT P+  G  +   R  GPGEF+  +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377

Query: 335 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 371
           KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414


>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
           alpha [Homo sapiens]
          Length = 406

 Score =  459 bits (1181), Expect = e-129
 Identities = 237/397 (59%), Positives = 283/397 (71%), Gaps = 59/397 (14%)

Query: 26  SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
           +KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V  PVML+PDDFKA SKIKV+
Sbjct: 16  TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75

Query: 86  NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYL---------------------- 123
           NHLF++EN+PSHFKFKEYCP VFRNLR+RFGIDDQD+                       
Sbjct: 76  NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135

Query: 124 -----------------------------YIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 154
                                        YIV+CHG TLLPQFLGMYR++VD  + Y++V
Sbjct: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195

Query: 155 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 214
            RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI +  KK+F
Sbjct: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255

Query: 215 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 274
           LEKLK+DVEFL QLK+MDYSLL+GIHD+ R    +EE    E++ E +G+   T P    
Sbjct: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309

Query: 275 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 334
              GT P+  G  ++S  PL PGEF+  IDVY I+  E +P+KEVYFM +IDILT YDAK
Sbjct: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367

Query: 335 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 371
           KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404


>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
           gamma [Homo sapiens]
          Length = 668

 Score =  139 bits (351), Expect = 3e-33
 Identities = 125/427 (29%), Positives = 182/427 (42%), Gaps = 75/427 (17%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           +A     P  V + TA PGPG G     +      +       +  L G    G+ +++ 
Sbjct: 33  LAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVG 92

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFKEYCPQVFRNLRDRF 115
            LS  P   +L+ D +   S    +       NL P+H    F+FK Y P  FR  R+ F
Sbjct: 93  HLSSKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHFQDFRFKTYAPVAFRYFRELF 148

Query: 116 GIDDQDYLY----------------------------IVKC------------------- 128
           GI   DYLY                            I+K                    
Sbjct: 149 GIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMN 208

Query: 129 ---HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEK 185
              +  TLLP+F G+Y V    ++  ++VM N+    + +H K+DLKGS   R AS KEK
Sbjct: 209 LNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEK 268

Query: 186 VKELPTLKDMDFL-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIR 244
            K  PT KD+DF+ +  + + +  +     ++ L+RD   L   KIMDYSLLLG+H+I  
Sbjct: 269 EKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNI-- 326

Query: 245 GSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGE-FESFI 303
             + E E   +  +S  D +    G  AL   Y T+ E I G          GE  ES  
Sbjct: 327 -DQHERERQAQGAQSTSD-EKRPVGQKAL---YSTAMESIQG------GAARGEAIESDD 375

Query: 304 DVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKR 363
            +  I +  G  ++ +  +G+IDIL  Y   KK  H  K + H  G  +S   P  YA+R
Sbjct: 376 TMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHD-GDTVSVHRPSFYAER 434

Query: 364 FLDFITN 370
           F  F++N
Sbjct: 435 FFKFMSN 441


>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
           isoform 2 [Homo sapiens]
          Length = 540

 Score =  135 bits (340), Expect = 6e-32
 Identities = 119/414 (28%), Positives = 172/414 (41%), Gaps = 78/414 (18%)

Query: 12  SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
           SAA  G   PG     KT KK           A+  + G    G+ +++  L+  P   +
Sbjct: 3   SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52

Query: 71  LLPDDFKASSKI--KVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLY---- 124
           L+ D +   S       ++L    + P  F+FK Y P  FR  R+ FGI   DYLY    
Sbjct: 53  LMQDFYVVESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICS 111

Query: 125 ------------------------IVKC----------------------HGNTLLPQFL 138
                                   I+K                       +  TLLP+F 
Sbjct: 112 EPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFY 171

Query: 139 GMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFL 198
           G+Y +     +  ++VM N+    + +H  YDLKGS   R AS KE+ K  PT KD+DFL
Sbjct: 172 GLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFL 231

Query: 199 -NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVRE 256
            + ++ +Y   E     ++ L+RD   L   KIMDYSLLLGIH +     E EEE P   
Sbjct: 232 QDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNV 291

Query: 257 DESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQ 316
            +++  G   +    A+    G    G G    +   +G            I +     +
Sbjct: 292 PDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRGE 340

Query: 317 KEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 370
           K + FMG+IDIL  Y   KK  H+ K + +  G  +S   P  YA RFL F+ +
Sbjct: 341 KLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393


>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 1 [Homo sapiens]
          Length = 562

 Score =  132 bits (333), Expect = 4e-31
 Identities = 113/380 (29%), Positives = 162/380 (42%), Gaps = 73/380 (19%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 85  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 140

Query: 102 EYCPQVFRNLRDRFGIDDQDYLY----------------------------IVKC----- 128
            Y P  FR  R+ FGI   DYLY                            I+K      
Sbjct: 141 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 200

Query: 129 -----------------HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDL 171
                            +  TLLP+F G+Y V    ++  ++VM N+    + +H KYDL
Sbjct: 201 AEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDL 260

Query: 172 KGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKI 230
           KGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   KI
Sbjct: 261 KGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKI 320

Query: 231 MDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHS 290
           MDYSLL+ IH+I       + A      SE         P      Y T+ E I G    
Sbjct: 321 MDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---E 370

Query: 291 HRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGA 350
            R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G 
Sbjct: 371 ARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GD 427

Query: 351 EISTVHPEQYAKRFLDFITN 370
            +S   P  YA+RF  F+ N
Sbjct: 428 TVSVHRPGFYAERFQRFMCN 447


>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 4 [Homo sapiens]
          Length = 500

 Score =  132 bits (333), Expect = 4e-31
 Identities = 113/380 (29%), Positives = 162/380 (42%), Gaps = 73/380 (19%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127

Query: 102 EYCPQVFRNLRDRFGIDDQDYLY----------------------------IVKC----- 128
            Y P  FR  R+ FGI   DYLY                            I+K      
Sbjct: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187

Query: 129 -----------------HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDL 171
                            +  TLLP+F G+Y V    ++  ++VM N+    + +H KYDL
Sbjct: 188 AEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDL 247

Query: 172 KGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKI 230
           KGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   KI
Sbjct: 248 KGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKI 307

Query: 231 MDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHS 290
           MDYSLL+ IH+I       + A      SE         P      Y T+ E I G    
Sbjct: 308 MDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---E 357

Query: 291 HRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGA 350
            R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G 
Sbjct: 358 ARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GD 414

Query: 351 EISTVHPEQYAKRFLDFITN 370
            +S   P  YA+RF  F+ N
Sbjct: 415 TVSVHRPGFYAERFQRFMCN 434


>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
           isoform 2 [Homo sapiens]
          Length = 549

 Score =  132 bits (333), Expect = 4e-31
 Identities = 113/380 (29%), Positives = 162/380 (42%), Gaps = 73/380 (19%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127

Query: 102 EYCPQVFRNLRDRFGIDDQDYLY----------------------------IVKC----- 128
            Y P  FR  R+ FGI   DYLY                            I+K      
Sbjct: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187

Query: 129 -----------------HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDL 171
                            +  TLLP+F G+Y V    ++  ++VM N+    + +H KYDL
Sbjct: 188 AEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDL 247

Query: 172 KGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKI 230
           KGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   KI
Sbjct: 248 KGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKI 307

Query: 231 MDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHS 290
           MDYSLL+ IH+I       + A      SE         P      Y T+ E I G    
Sbjct: 308 MDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---E 357

Query: 291 HRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGA 350
            R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G 
Sbjct: 358 ARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GD 414

Query: 351 EISTVHPEQYAKRFLDFITN 370
            +S   P  YA+RF  F+ N
Sbjct: 415 TVSVHRPGFYAERFQRFMCN 434


>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 3 [Homo sapiens]
          Length = 522

 Score =  107 bits (268), Expect = 1e-23
 Identities = 105/380 (27%), Positives = 146/380 (38%), Gaps = 101/380 (26%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 73  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 128

Query: 102 EYCPQVFRNLRDRFGIDDQDYLY----------------------------IVKC----- 128
            Y P  FR  R+ FGI   DYLY                            I+K      
Sbjct: 129 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 188

Query: 129 -----------------HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDL 171
                            +  TLLP+F G+Y V    ++  ++VM N+    + +H KYDL
Sbjct: 189 AEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDL 248

Query: 172 KGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKI 230
           KGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   KI
Sbjct: 249 KGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKI 308

Query: 231 MDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHS 290
           MDYSLL+ IH+I       + A      SE         P      Y T+ E I G    
Sbjct: 309 MDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---- 357

Query: 291 HRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGA 350
                                      E    G ++   Q+   KK  H+ K + H  G 
Sbjct: 358 ---------------------------EARRGGTMETDDQF--VKKLEHSWKALVHD-GD 387

Query: 351 EISTVHPEQYAKRFLDFITN 370
            +S   P  YA+RF  F+ N
Sbjct: 388 TVSVHRPGFYAERFQRFMCN 407


>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 1 [Homo sapiens]
          Length = 394

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 69/249 (27%), Positives = 117/249 (46%), Gaps = 31/249 (12%)

Query: 122 YLYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREA 180
           Y+  ++ H ++LL + LG++ + VD  + +Y +VM+++F     +  +YD+KG  VSR  
Sbjct: 170 YVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWV 229

Query: 181 SDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGI 239
               +   L   LKD++F  K   + +G + +  FL +++ D  FL +L ++DYSLL+  
Sbjct: 230 DPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDYSLLIAF 286

Query: 240 HDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEF 299
                          R  E E     SL    A       SPE          P  P   
Sbjct: 287 Q--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLPDAPN-- 330

Query: 300 ESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQ 359
                  A+   +G  Q+  YF+G++D+ T Y  +K+  H  KT+++  G   STV P +
Sbjct: 331 -------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFSTVSPAR 380

Query: 360 YAKRFLDFI 368
           YA+R   ++
Sbjct: 381 YARRLCQWV 389


>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 2 [Homo sapiens]
          Length = 191

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 59/215 (27%), Positives = 95/215 (44%), Gaps = 30/215 (13%)

Query: 155 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKI 213
           M+++F     +  +YD+KG  VSR      +   L   LKD++F  K   + +G + +  
Sbjct: 1   MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSW 57

Query: 214 FLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPAL 273
           FL +++ D  FL +L ++DYSLL+                 R  E E     SL    A 
Sbjct: 58  FLRQMELDTTFLRELNVLDYSLLIAFQ--------------RLHEDERGPGSSLIFRTAR 103

Query: 274 VGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDA 333
                 SPE          P  P          A+   +G  Q+  YF+G++D+ T Y  
Sbjct: 104 SVQGAQSPEESRAQNRRLLPDAPN---------ALHILDGPEQR--YFLGVVDLATVYGL 152

Query: 334 KKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFI 368
           +K+  H  KT+++  G   STV P +YA+R   ++
Sbjct: 153 RKRLEHLWKTLRY-PGRTFSTVSPARYARRLCQWV 186


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
            isoform 2 [Homo sapiens]
          Length = 2098

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 10/119 (8%)

Query: 132  TLLPQFLGMYRVSVDNEDSY------MLVMRNMFSHRLPVHRKYDLKGSLVSREA-SDKE 184
            T L + LG+YR+   N  +       +LVM N+F  R  + + +DLKGSL +R   +D  
Sbjct: 1908 TALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRNVKTDTG 1966

Query: 185  KVKELPTLKDMDFLN--KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHD 241
            K      L D + L   ++  +YI    K +    +  D  FL    I+DYSLL+G  D
Sbjct: 1967 KESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score = 32.7 bits (73), Expect = 0.54
 Identities = 26/93 (27%), Positives = 36/93 (38%), Gaps = 17/93 (18%)

Query: 255 REDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGA 314
           RED+ +VD          L G+YG+SP    G   +  P  P E E          A+G 
Sbjct: 77  REDDEDVD---------QLFGAYGSSPGPSPGPSPARPPAKPPEDEP--------DADGY 119

Query: 315 PQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHG 347
              +   +G +D    YD +  A H   T   G
Sbjct: 120 ESDDCTALGTLDFSLLYDQENNALHCTITKAKG 152


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 188
           L+P++L   R  VD+ED  + + R M   S  L V RK  +K    L S  A DKE  K 
Sbjct: 369 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYK- 427

Query: 189 LPTLKDMDFLNKNQKVYIGEE 209
               K  +  +KN K+ I E+
Sbjct: 428 ----KFYEAFSKNLKLGIHED 444


>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
          Length = 828

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 11 VSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
          V+AA A PG G   AS  +K H++    +         G+  W + ++I+E ++     M
Sbjct: 15 VAAAGAQPGSGENTASVLQKDHYLDSSWRTEN------GLIPWTLDNTISEENRAVIEKM 68

Query: 71 LLPDDFKASSK 81
          LL +++  S K
Sbjct: 69 LLEEEYYLSKK 79


>gi|29789078 UDP glycosyltransferase 1 family, polypeptide A10
           precursor [Homo sapiens]
          Length = 530

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 13/67 (19%)

Query: 50  VFLWGV-AHSINELSQVPPPVMLLPDDFKASS-----KIKVNNHLFHRENLPSHFKFKEY 103
           VF  G+  H + E +Q P P+  +P+D    S     K +V NH+ H E+   H     +
Sbjct: 167 VFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLED---HL----F 219

Query: 104 CPQVFRN 110
           C  +FRN
Sbjct: 220 CQYLFRN 226


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)

Query: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 188
           L+P++L   R  VD+ED  + + R M   S  L V RK  +K    L +  A DKE  K 
Sbjct: 377 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 435

Query: 189 LPTLKDMDFLNKNQKVYIGEEEK 211
               K  +  +KN K+ I E+ +
Sbjct: 436 ----KFYEQFSKNIKLGIHEDSQ 454


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)

Query: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 188
           L+P++L   R  VD+ED  + + R M   S  L V RK  +K    L +  A DKE  K 
Sbjct: 499 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 557

Query: 189 LPTLKDMDFLNKNQKVYIGEEEK 211
               K  +  +KN K+ I E+ +
Sbjct: 558 ----KFYEQFSKNIKLGIHEDSQ 576


>gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo
           sapiens]
          Length = 169

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 153 LVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKK 212
           LV+R   S RLPV R    +GS    E S   +   L + K+ D   +  K+   EE+ K
Sbjct: 54  LVLRRDSSQRLPVARPRRSRGS----ENSHSSQSFHLASNKNRDIFAEALKIQESEEKVK 109

Query: 213 IFLEKLKRDVEFLVQLK 229
            +L+K K   E L  L+
Sbjct: 110 -YLQKAKTREEILQLLR 125


>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
          Length = 595

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (6%)

Query: 201 NQKVYIGEEEKKIFLEK----LKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVRE 256
           ++K+ + E ++K F E     +K++ E + QL+    +L L + D+++G E   +A +RE
Sbjct: 75  HKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLDLLKGDEKVVQAVIRE 134


>gi|50053795 eukaryotic translation initiation factor 4B [Homo
           sapiens]
          Length = 611

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 4/41 (9%)

Query: 246 SEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGG 286
           ++P EE P R+DE++VDG   +  P    G+    P G GG
Sbjct: 515 AQPSEEGPGRKDENKVDG---MNAPKGQTGNSSRGP-GDGG 551


>gi|4758220 XAP-5 protein [Homo sapiens]
          Length = 339

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 15/93 (16%)

Query: 179 EASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF-----------LEKLKRDVEFLVQ 227
           EA  K     L TL DM      Q+  + E EK++            LEKL R+ E   +
Sbjct: 57  EAELKSSTVGLVTLNDM---KAKQEALVKEREKQLAKKEQSKELQMKLEKL-REKERKKE 112

Query: 228 LKIMDYSLLLGIHDIIRGSEPEEEAPVREDESE 260
            K    SL   + +   G E EEEA + E+E E
Sbjct: 113 AKRKISSLSFTLEEEEEGGEEEEEAAMYEEEME 145


>gi|145580615 KRI1 homolog [Homo sapiens]
          Length = 709

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 15/45 (33%), Positives = 22/45 (48%)

Query: 239 IHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEG 283
           + D I     EEE    EDE E++ +  + GPP  +    +S EG
Sbjct: 246 LRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEG 290


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 14/54 (25%), Positives = 28/54 (51%)

Query: 164 PVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEK 217
           P   +   + S    E+SD+E+ ++LP  +  +   + +K Y G+  KK  ++K
Sbjct: 126 PAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKK 179


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 14/115 (12%)

Query: 7   PPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQV- 65
           PP T+S A    G G    S+    H + ++V++     P V      V  S ++ S V 
Sbjct: 623 PPPTLSPAAITVGRGEDLTSE----HPLLEQVEL-----PAVASVSASVIKSPSDPSHVS 673

Query: 66  -PPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDD 119
            PPP +LLP     S+   +++ +   EN P     K   PQ+  ++ + F I +
Sbjct: 674 VPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVK---PQILTHVIEGFVIQE 725


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,482,841
Number of Sequences: 37866
Number of extensions: 744418
Number of successful extensions: 2426
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2372
Number of HSP's gapped (non-prelim): 43
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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