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Search of human proteins with 226371739
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type
II, gamma isoform a [Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,... 849 0.0
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,... 849 0.0
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,... 798 0.0
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,... 733 0.0
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b... 535 e-152
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a... 525 e-149
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g... 167 2e-41
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 163 3e-40
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 163 3e-40
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al... 163 3e-40
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be... 162 4e-40
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 138 1e-32
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is... 99 7e-21
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso... 65 9e-11
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 62 1e-09
gi|6005997 double C2-like domains, beta [Homo sapiens] 33 0.63
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] 32 1.1
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens] 32 1.1
gi|29789078 UDP glycosyltransferase 1 family, polypeptide A10 pr... 30 3.1
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s... 30 4.1
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s... 30 4.1
gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo sapi... 30 4.1
gi|117553613 coiled-coil domain containing 151 [Homo sapiens] 30 4.1
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa... 30 5.4
gi|4758220 XAP-5 protein [Homo sapiens] 29 7.0
gi|145580615 KRI1 homolog [Homo sapiens] 29 7.0
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 29 7.0
gi|148612879 polyhomeotic like 3 [Homo sapiens] 29 9.2
>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 849 bits (2194), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
Query: 421 A 421
A
Sbjct: 421 A 421
>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 849 bits (2194), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
Query: 421 A 421
A
Sbjct: 421 A 421
>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform b [Homo sapiens]
Length = 403
Score = 798 bits (2062), Expect = 0.0
Identities = 403/421 (95%), Positives = 403/421 (95%), Gaps = 18/421 (4%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
ELSQVPPPVMLLPDDFKASSKIK EYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIK------------------EYCPQVFRNLRDRFGIDDQ 102
Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 103 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 162
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 222
Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 223 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 282
Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 283 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 342
Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 343 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 402
Query: 421 A 421
A
Sbjct: 403 A 403
>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform c [Homo sapiens]
Length = 373
Score = 733 bits (1891), Expect = 0.0
Identities = 373/421 (88%), Positives = 373/421 (88%), Gaps = 48/421 (11%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
DYL YIVKCHGNT
Sbjct: 121 DYL------------------------------------------------YIVKCHGNT 132
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 192
Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 193 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 252
Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 253 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 312
Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 313 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 372
Query: 421 A 421
A
Sbjct: 373 A 373
>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
[Homo sapiens]
Length = 416
Score = 535 bits (1379), Expect = e-152
Identities = 267/397 (67%), Positives = 324/397 (81%), Gaps = 6/397 (1%)
Query: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
+KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIKV+
Sbjct: 21 TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80
Query: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFL 142
NHLF++ENLPS FKFKEYCP VFRNLR+RFGIDDQDY S+TR+ P S+S+G G RFL
Sbjct: 81 NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140
Query: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
+YDR VIK VSSED+A+MH+ L YHQ+IV+CHGNTLLPQFLGMYR++VD ++YM+V
Sbjct: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200
Query: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260
Query: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
LEKLKRDVEFL QLKIMDYSLL+GIHD+ R + E E R ++ E + D + G L+
Sbjct: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317
Query: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
SYGT P+ G + R GPGEF+ +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
Query: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414
>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
alpha [Homo sapiens]
Length = 406
Score = 525 bits (1352), Expect = e-149
Identities = 260/397 (65%), Positives = 316/397 (79%), Gaps = 11/397 (2%)
Query: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
+KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V PVML+PDDFKA SKIKV+
Sbjct: 16 TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75
Query: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEG---SDGRFL 142
NHLF++EN+PSHFKFKEYCP VFRNLR+RFGIDDQD+ SLTR+ P ++ S RF
Sbjct: 76 NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135
Query: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
SYD+ +IK ++SED+A+MH+ L YHQYIV+CHG TLLPQFLGMYR++VD + Y++V
Sbjct: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195
Query: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI + KK+F
Sbjct: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255
Query: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
LEKLK+DVEFL QLK+MDYSLL+GIHD+ R +EE E++ E +G+ T P
Sbjct: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309
Query: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
GT P+ G ++S PL PGEF+ IDVY I+ E +P+KEVYFM +IDILT YDAK
Sbjct: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
Query: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404
>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
gamma [Homo sapiens]
Length = 668
Score = 167 bits (423), Expect = 2e-41
Identities = 135/428 (31%), Positives = 202/428 (47%), Gaps = 29/428 (6%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
+A P V + TA PGPG G + + + L G G+ +++
Sbjct: 33 LAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVG 92
Query: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFKEYCPQVFRNLRDRF 115
LS P +L+ D + S + NL P+H F+FK Y P FR R+ F
Sbjct: 93 HLSSKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHFQDFRFKTYAPVAFRYFRELF 148
Query: 116 GIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQY 172
GI DYL SL P E + G+ G F ++ D +IK V ++ + L Y+
Sbjct: 149 GIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMN 208
Query: 173 IVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKE 232
+ + + TLLP+F G+Y V ++ ++VM N+ + +H K+DLKGS R AS KE
Sbjct: 209 LNQ-NPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKE 267
Query: 233 KVKELPTLKDMDFL-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDII 291
K K PT KD+DF+ + + + + + ++ L+RD L KIMDYSLLLG+H+I
Sbjct: 268 KEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNI- 326
Query: 292 RGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGE-FESF 350
+ E E + +S D + G AL Y T+ E I G GE ES
Sbjct: 327 --DQHERERQAQGAQSTSD-EKRPVGQKAL---YSTAMESIQG------GAARGEAIESD 374
Query: 351 IDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAK 410
+ I + G ++ + +G+IDIL Y KK H K + H G +S P YA+
Sbjct: 375 DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHD-GDTVSVHRPSFYAE 433
Query: 411 RFLDFITN 418
RF F++N
Sbjct: 434 RFFKFMSN 441
>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 1 [Homo sapiens]
Length = 562
Score = 163 bits (412), Expect = 3e-40
Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
L G G+ H++ LS P +L+ D + S + NL P+H F+FK
Sbjct: 85 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 140
Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
Y P FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++
Sbjct: 141 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 200
Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
+ L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYD
Sbjct: 201 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 259
Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
LKGS R AS KE+ K LPT KD+DFL +++ + + L+RD L K
Sbjct: 260 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 319
Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
IMDYSLL+ IH+I + A SE P Y T+ E I G
Sbjct: 320 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 369
Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
R G E + + R+++G ++ + ++G+IDIL Y KK H+ K + H G
Sbjct: 370 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 426
Query: 398 AEISTVHPEQYAKRFLDFITN 418
+S P YA+RF F+ N
Sbjct: 427 DTVSVHRPGFYAERFQRFMCN 447
>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 4 [Homo sapiens]
Length = 500
Score = 163 bits (412), Expect = 3e-40
Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
L G G+ H++ LS P +L+ D + S + NL P+H F+FK
Sbjct: 72 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127
Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
Y P FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++
Sbjct: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187
Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
+ L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYD
Sbjct: 188 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 246
Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
LKGS R AS KE+ K LPT KD+DFL +++ + + L+RD L K
Sbjct: 247 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 306
Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
IMDYSLL+ IH+I + A SE P Y T+ E I G
Sbjct: 307 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 356
Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
R G E + + R+++G ++ + ++G+IDIL Y KK H+ K + H G
Sbjct: 357 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 413
Query: 398 AEISTVHPEQYAKRFLDFITN 418
+S P YA+RF F+ N
Sbjct: 414 DTVSVHRPGFYAERFQRFMCN 434
>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
isoform 2 [Homo sapiens]
Length = 549
Score = 163 bits (412), Expect = 3e-40
Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
L G G+ H++ LS P +L+ D + S + NL P+H F+FK
Sbjct: 72 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127
Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
Y P FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++
Sbjct: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187
Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
+ L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYD
Sbjct: 188 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 246
Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
LKGS R AS KE+ K LPT KD+DFL +++ + + L+RD L K
Sbjct: 247 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 306
Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
IMDYSLL+ IH+I + A SE P Y T+ E I G
Sbjct: 307 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 356
Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
R G E + + R+++G ++ + ++G+IDIL Y KK H+ K + H G
Sbjct: 357 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 413
Query: 398 AEISTVHPEQYAKRFLDFITN 418
+S P YA+RF F+ N
Sbjct: 414 DTVSVHRPGFYAERFQRFMCN 434
>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
isoform 2 [Homo sapiens]
Length = 540
Score = 162 bits (411), Expect = 4e-40
Identities = 128/415 (30%), Positives = 192/415 (46%), Gaps = 32/415 (7%)
Query: 12 SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
SAA G PG KT KK A+ + G G+ +++ L+ P +
Sbjct: 3 SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52
Query: 71 LLPDDFKASSKI--KVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTR 128
L+ D + S ++L + P F+FK Y P FR R+ FGI DYL S+
Sbjct: 53 LMQDFYVVESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICS 111
Query: 129 NPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQF 185
P E + G+ G F ++ D +IK V ++ + L Y+ + + + TLLP+F
Sbjct: 112 EPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKF 170
Query: 186 LGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDF 245
G+Y + + ++VM N+ + +H YDLKGS R AS KE+ K PT KD+DF
Sbjct: 171 YGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDF 230
Query: 246 L-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVR 303
L + ++ +Y E ++ L+RD L KIMDYSLLLGIH + E EEE P
Sbjct: 231 LQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQN 290
Query: 304 EDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAP 363
+++ G + A+ G G G + +G I +
Sbjct: 291 VPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRG 339
Query: 364 QKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 418
+K + FMG+IDIL Y KK H+ K + + G +S P YA RFL F+ +
Sbjct: 340 EKLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 3 [Homo sapiens]
Length = 522
Score = 138 bits (347), Expect = 1e-32
Identities = 117/381 (30%), Positives = 166/381 (43%), Gaps = 55/381 (14%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
L G G+ H++ LS P +L+ D + S + NL P+H F+FK
Sbjct: 73 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 128
Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
Y P FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++
Sbjct: 129 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 188
Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
+ L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYD
Sbjct: 189 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 247
Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
LKGS R AS KE+ K LPT KD+DFL +++ + + L+RD L K
Sbjct: 248 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 307
Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
IMDYSLL+ IH+I + A SE P Y T+ E I G
Sbjct: 308 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 357
Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
E G ++ Q+ KK H+ K + H G
Sbjct: 358 ----------------------------EARRGGTMETDDQF--VKKLEHSWKALVHD-G 386
Query: 398 AEISTVHPEQYAKRFLDFITN 418
+S P YA+RF F+ N
Sbjct: 387 DTVSVHRPGFYAERFQRFMCN 407
>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 1 [Homo sapiens]
Length = 394
Score = 99.0 bits (245), Expect = 7e-21
Identities = 84/315 (26%), Positives = 146/315 (46%), Gaps = 36/315 (11%)
Query: 108 FRNLRDRFGIDDQDYLVSLTRNPPS----ESEGSDGRFLISYDRTLVIKEVSSEDIADMH 163
F LR G+ ++DY +L P + S F +S+D+ +K ++ +
Sbjct: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
Query: 164 SNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGS 222
++L Y Q++ + H ++LL + LG++ + VD + +Y +VM+++F + +YD+KG
Sbjct: 165 AHLPRYVQHLQR-HPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
Query: 223 LVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 281
VSR + L LKD++F K + +G + + FL +++ D FL +L ++DY
Sbjct: 224 EVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
Query: 282 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 341
SLL+ R E E SL A SPE P
Sbjct: 281 SLLIAFQ--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLP 326
Query: 342 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 401
P A+ +G Q+ YF+G++D+ T Y +K+ H KT+++ G S
Sbjct: 327 DAPN---------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFS 374
Query: 402 TVHPEQYAKRFLDFI 416
TV P +YA+R ++
Sbjct: 375 TVSPARYARRLCQWV 389
>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 2 [Homo sapiens]
Length = 191
Score = 65.5 bits (158), Expect = 9e-11
Identities = 59/215 (27%), Positives = 95/215 (44%), Gaps = 30/215 (13%)
Query: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKI 261
M+++F + +YD+KG VSR + L LKD++F K + +G + +
Sbjct: 1 MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSW 57
Query: 262 FLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPAL 321
FL +++ D FL +L ++DYSLL+ R E E SL A
Sbjct: 58 FLRQMELDTTFLRELNVLDYSLLIAFQ--------------RLHEDERGPGSSLIFRTAR 103
Query: 322 VGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDA 381
SPE P P A+ +G Q+ YF+G++D+ T Y
Sbjct: 104 SVQGAQSPEESRAQNRRLLPDAPN---------ALHILDGPEQR--YFLGVVDLATVYGL 152
Query: 382 KKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFI 416
+K+ H KT+++ G STV P +YA+R ++
Sbjct: 153 RKRLEHLWKTLRY-PGRTFSTVSPARYARRLCQWV 186
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 62.0 bits (149), Expect = 1e-09
Identities = 52/185 (28%), Positives = 88/185 (47%), Gaps = 15/185 (8%)
Query: 119 DQDYLVSLTRNPPSESEG--SDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYI--- 173
++D++ SL+ + P ++ G S F + D ++K++ ++ +Y YI
Sbjct: 1842 EEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNA 1901
Query: 174 VKCHGNTLLPQFLGMYRVSVDNEDSY------MLVMRNMFSHRLPVHRKYDLKGSLVSRE 227
V+ T L + LG+YR+ N + +LVM N+F R + + +DLKGSL +R
Sbjct: 1902 VQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRN 1960
Query: 228 A-SDKEKVKELPTLKDMDFLN--KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLL 284
+D K L D + L ++ +YI K + + D FL I+DYSLL
Sbjct: 1961 VKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLL 2020
Query: 285 LGIHD 289
+G D
Sbjct: 2021 VGRDD 2025
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 32.7 bits (73), Expect = 0.63
Identities = 26/93 (27%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 303 REDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGA 362
RED+ +VD L G+YG+SP G + P P E E A+G
Sbjct: 77 REDDEDVD---------QLFGAYGSSPGPSPGPSPARPPAKPPEDEP--------DADGY 119
Query: 363 PQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHG 395
+ +G +D YD + A H T G
Sbjct: 120 ESDDCTALGTLDFSLLYDQENNALHCTITKAKG 152
>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
Length = 828
Score = 32.0 bits (71), Expect = 1.1
Identities = 41/188 (21%), Positives = 75/188 (39%), Gaps = 13/188 (6%)
Query: 11 VSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
V+AA A PG G AS +K H++ + G+ W + ++I+E ++ M
Sbjct: 15 VAAAGAQPGSGENTASVLQKDHYLDSSWRTEN------GLIPWTLDNTISEENRAVIEKM 68
Query: 71 LLPDDFKASSKIKVNN-HLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRN 129
LL +++ S K + L +E+ + K + ++ + + Y V T
Sbjct: 69 LLEEEYYLSKKSQPEKVWLDQKEDDKKYMKSLQKTAKIMVHSPTK----PASYSVKWTIE 124
Query: 130 PPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMY 189
E +F + T + K + S + + S Y + VKC + P +
Sbjct: 125 EKELFEQGLAKFGRRW--TKISKLIGSRTVLQVKSYARQYFKNKVKCGLDKETPNQKTGH 182
Query: 190 RVSVDNED 197
+ V NED
Sbjct: 183 NLQVKNED 190
>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
Length = 724
Score = 32.0 bits (71), Expect = 1.1
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 236
L+P++L R VD+ED + + R M S L V RK +K L S A DKE K
Sbjct: 369 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYK- 427
Query: 237 LPTLKDMDFLNKNQKVYIGEE 257
K + +KN K+ I E+
Sbjct: 428 ----KFYEAFSKNLKLGIHED 444
>gi|29789078 UDP glycosyltransferase 1 family, polypeptide A10
precursor [Homo sapiens]
Length = 530
Score = 30.4 bits (67), Expect = 3.1
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 13/67 (19%)
Query: 50 VFLWGV-AHSINELSQVPPPVMLLPDDFKASS-----KIKVNNHLFHRENLPSHFKFKEY 103
VF G+ H + E +Q P P+ +P+D S K +V NH+ H E+ H +
Sbjct: 167 VFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLED---HL----F 219
Query: 104 CPQVFRN 110
C +FRN
Sbjct: 220 CQYLFRN 226
>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
sapiens]
Length = 732
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 236
L+P++L R VD+ED + + R M S L V RK +K L + A DKE K
Sbjct: 377 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 435
Query: 237 LPTLKDMDFLNKNQKVYIGEEEK 259
K + +KN K+ I E+ +
Sbjct: 436 ----KFYEQFSKNIKLGIHEDSQ 454
>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 30.0 bits (66), Expect = 4.1
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)
Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 236
L+P++L R VD+ED + + R M S L V RK +K L + A DKE K
Sbjct: 499 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 557
Query: 237 LPTLKDMDFLNKNQKVYIGEEEK 259
K + +KN K+ I E+ +
Sbjct: 558 ----KFYEQFSKNIKLGIHEDSQ 576
>gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo
sapiens]
Length = 169
Score = 30.0 bits (66), Expect = 4.1
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 201 LVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKK 260
LV+R S RLPV R +GS E S + L + K+ D + K+ EE+ K
Sbjct: 54 LVLRRDSSQRLPVARPRRSRGS----ENSHSSQSFHLASNKNRDIFAEALKIQESEEKVK 109
Query: 261 IFLEKLKRDVEFLVQLK 277
+L+K K E L L+
Sbjct: 110 -YLQKAKTREEILQLLR 125
>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
Length = 595
Score = 30.0 bits (66), Expect = 4.1
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 249 NQKVYIGEEEKKIFLEK----LKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVRE 304
++K+ + E ++K F E +K++ E + QL+ +L L + D+++G E +A +RE
Sbjct: 75 HKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLDLLKGDEKVVQAVIRE 134
>gi|50053795 eukaryotic translation initiation factor 4B [Homo
sapiens]
Length = 611
Score = 29.6 bits (65), Expect = 5.4
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
Query: 294 SEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGG 334
++P EE P R+DE++VDG + P G+ P G GG
Sbjct: 515 AQPSEEGPGRKDENKVDG---MNAPKGQTGNSSRGP-GDGG 551
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 29.3 bits (64), Expect = 7.0
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 15/93 (16%)
Query: 227 EASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF-----------LEKLKRDVEFLVQ 275
EA K L TL DM Q+ + E EK++ LEKL R+ E +
Sbjct: 57 EAELKSSTVGLVTLNDM---KAKQEALVKEREKQLAKKEQSKELQMKLEKL-REKERKKE 112
Query: 276 LKIMDYSLLLGIHDIIRGSEPEEEAPVREDESE 308
K SL + + G E EEEA + E+E E
Sbjct: 113 AKRKISSLSFTLEEEEEGGEEEEEAAMYEEEME 145
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 29.3 bits (64), Expect = 7.0
Identities = 15/45 (33%), Positives = 22/45 (48%)
Query: 287 IHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEG 331
+ D I EEE EDE E++ + + GPP + +S EG
Sbjct: 246 LRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEG 290
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 29.3 bits (64), Expect = 7.0
Identities = 14/54 (25%), Positives = 28/54 (51%)
Query: 212 PVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEK 265
P + + S E+SD+E+ ++LP + + + +K Y G+ KK ++K
Sbjct: 126 PAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKK 179
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 28.9 bits (63), Expect = 9.2
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 7 PPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQV- 65
PP T+S A G G S+ H + ++V++ P V V S ++ S V
Sbjct: 623 PPPTLSPAAITVGRGEDLTSE----HPLLEQVEL-----PAVASVSASVIKSPSDPSHVS 673
Query: 66 -PPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDD 119
PPP +LLP S+ +++ + EN P K PQ+ ++ + F I +
Sbjct: 674 VPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVK---PQILTHVIEGFVIQE 725
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,279,291
Number of Sequences: 37866
Number of extensions: 817768
Number of successful extensions: 2653
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2599
Number of HSP's gapped (non-prelim): 34
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.