Guide to the Human Genome
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Search of human proteins with 226371739

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type
II, gamma isoform a [Homo sapiens]
         (421 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,...   849   0.0  
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,...   849   0.0  
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,...   798   0.0  
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,...   733   0.0  
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b...   535   e-152
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a...   525   e-149
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g...   167   2e-41
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   163   3e-40
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   163   3e-40
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al...   163   3e-40
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be...   162   4e-40
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   138   1e-32
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is...    99   7e-21
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso...    65   9e-11
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    62   1e-09
gi|6005997 double C2-like domains, beta [Homo sapiens]                 33   0.63 
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]          32   1.1  
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            32   1.1  
gi|29789078 UDP glycosyltransferase 1 family, polypeptide A10 pr...    30   3.1  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...    30   4.1  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...    30   4.1  
gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo sapi...    30   4.1  
gi|117553613 coiled-coil domain containing 151 [Homo sapiens]          30   4.1  
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa...    30   5.4  
gi|4758220 XAP-5 protein [Homo sapiens]                                29   7.0  
gi|145580615 KRI1 homolog [Homo sapiens]                               29   7.0  
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  29   7.0  
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        29   9.2  

>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score =  849 bits (2194), Expect = 0.0
 Identities = 421/421 (100%), Positives = 421/421 (100%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120

Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
           DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240

Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300

Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360

Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420

Query: 421 A 421
           A
Sbjct: 421 A 421


>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score =  849 bits (2194), Expect = 0.0
 Identities = 421/421 (100%), Positives = 421/421 (100%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120

Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
           DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240

Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300

Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360

Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420

Query: 421 A 421
           A
Sbjct: 421 A 421


>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform b [Homo sapiens]
          Length = 403

 Score =  798 bits (2062), Expect = 0.0
 Identities = 403/421 (95%), Positives = 403/421 (95%), Gaps = 18/421 (4%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIK                  EYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIK------------------EYCPQVFRNLRDRFGIDDQ 102

Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
           DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 103 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 162

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 222

Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 223 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 282

Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 283 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 342

Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 343 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 402

Query: 421 A 421
           A
Sbjct: 403 A 403


>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform c [Homo sapiens]
          Length = 373

 Score =  733 bits (1891), Expect = 0.0
 Identities = 373/421 (88%), Positives = 373/421 (88%), Gaps = 48/421 (11%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
           ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
Sbjct: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120

Query: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
           DYL                                                YIVKCHGNT
Sbjct: 121 DYL------------------------------------------------YIVKCHGNT 132

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
           LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 192

Query: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
           KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 193 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 252

Query: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
           PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 253 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 312

Query: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
           GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 313 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 372

Query: 421 A 421
           A
Sbjct: 373 A 373


>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
           [Homo sapiens]
          Length = 416

 Score =  535 bits (1379), Expect = e-152
 Identities = 267/397 (67%), Positives = 324/397 (81%), Gaps = 6/397 (1%)

Query: 26  SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
           +KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIKV+
Sbjct: 21  TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80

Query: 86  NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFL 142
           NHLF++ENLPS FKFKEYCP VFRNLR+RFGIDDQDY  S+TR+ P  S+S+G  G RFL
Sbjct: 81  NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140

Query: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
            +YDR  VIK VSSED+A+MH+ L  YHQ+IV+CHGNTLLPQFLGMYR++VD  ++YM+V
Sbjct: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200

Query: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
            RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260

Query: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
           LEKLKRDVEFL QLKIMDYSLL+GIHD+ R  + E E   R ++ E + D  + G   L+
Sbjct: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317

Query: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
            SYGT P+  G  +   R  GPGEF+  +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377

Query: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
           KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414


>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
           alpha [Homo sapiens]
          Length = 406

 Score =  525 bits (1352), Expect = e-149
 Identities = 260/397 (65%), Positives = 316/397 (79%), Gaps = 11/397 (2%)

Query: 26  SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
           +KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V  PVML+PDDFKA SKIKV+
Sbjct: 16  TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75

Query: 86  NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEG---SDGRFL 142
           NHLF++EN+PSHFKFKEYCP VFRNLR+RFGIDDQD+  SLTR+ P  ++    S  RF 
Sbjct: 76  NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135

Query: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
            SYD+  +IK ++SED+A+MH+ L  YHQYIV+CHG TLLPQFLGMYR++VD  + Y++V
Sbjct: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195

Query: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
            RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI +  KK+F
Sbjct: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255

Query: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
           LEKLK+DVEFL QLK+MDYSLL+GIHD+ R    +EE    E++ E +G+   T P    
Sbjct: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309

Query: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
              GT P+  G  ++S  PL PGEF+  IDVY I+  E +P+KEVYFM +IDILT YDAK
Sbjct: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367

Query: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
           KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404


>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
           gamma [Homo sapiens]
          Length = 668

 Score =  167 bits (423), Expect = 2e-41
 Identities = 135/428 (31%), Positives = 202/428 (47%), Gaps = 29/428 (6%)

Query: 1   MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
           +A     P  V + TA PGPG G     +      +       +  L G    G+ +++ 
Sbjct: 33  LAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVG 92

Query: 61  ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFKEYCPQVFRNLRDRF 115
            LS  P   +L+ D +   S    +       NL P+H    F+FK Y P  FR  R+ F
Sbjct: 93  HLSSKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHFQDFRFKTYAPVAFRYFRELF 148

Query: 116 GIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQY 172
           GI   DYL SL   P  E  + G+ G  F ++ D   +IK V  ++   +   L  Y+  
Sbjct: 149 GIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMN 208

Query: 173 IVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKE 232
           + + +  TLLP+F G+Y V    ++  ++VM N+    + +H K+DLKGS   R AS KE
Sbjct: 209 LNQ-NPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKE 267

Query: 233 KVKELPTLKDMDFL-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDII 291
           K K  PT KD+DF+ +  + + +  +     ++ L+RD   L   KIMDYSLLLG+H+I 
Sbjct: 268 KEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNI- 326

Query: 292 RGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGE-FESF 350
              + E E   +  +S  D +    G  AL   Y T+ E I G          GE  ES 
Sbjct: 327 --DQHERERQAQGAQSTSD-EKRPVGQKAL---YSTAMESIQG------GAARGEAIESD 374

Query: 351 IDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAK 410
             +  I +  G  ++ +  +G+IDIL  Y   KK  H  K + H  G  +S   P  YA+
Sbjct: 375 DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHD-GDTVSVHRPSFYAE 433

Query: 411 RFLDFITN 418
           RF  F++N
Sbjct: 434 RFFKFMSN 441


>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 1 [Homo sapiens]
          Length = 562

 Score =  163 bits (412), Expect = 3e-40
 Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 85  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 140

Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
            Y P  FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++
Sbjct: 141 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 200

Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
              +   L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYD
Sbjct: 201 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 259

Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
           LKGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   K
Sbjct: 260 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 319

Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
           IMDYSLL+ IH+I       + A      SE         P      Y T+ E I G   
Sbjct: 320 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 369

Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
             R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G
Sbjct: 370 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 426

Query: 398 AEISTVHPEQYAKRFLDFITN 418
             +S   P  YA+RF  F+ N
Sbjct: 427 DTVSVHRPGFYAERFQRFMCN 447


>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 4 [Homo sapiens]
          Length = 500

 Score =  163 bits (412), Expect = 3e-40
 Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127

Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
            Y P  FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++
Sbjct: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187

Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
              +   L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYD
Sbjct: 188 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 246

Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
           LKGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   K
Sbjct: 247 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 306

Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
           IMDYSLL+ IH+I       + A      SE         P      Y T+ E I G   
Sbjct: 307 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 356

Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
             R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G
Sbjct: 357 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 413

Query: 398 AEISTVHPEQYAKRFLDFITN 418
             +S   P  YA+RF  F+ N
Sbjct: 414 DTVSVHRPGFYAERFQRFMCN 434


>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
           isoform 2 [Homo sapiens]
          Length = 549

 Score =  163 bits (412), Expect = 3e-40
 Identities = 125/381 (32%), Positives = 182/381 (47%), Gaps = 27/381 (7%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 72  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 127

Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
            Y P  FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++
Sbjct: 128 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 187

Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
              +   L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYD
Sbjct: 188 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 246

Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
           LKGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   K
Sbjct: 247 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 306

Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
           IMDYSLL+ IH+I       + A      SE         P      Y T+ E I G   
Sbjct: 307 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 356

Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
             R  G  E +  +     R+++G  ++ + ++G+IDIL  Y   KK  H+ K + H  G
Sbjct: 357 EARRGGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-G 413

Query: 398 AEISTVHPEQYAKRFLDFITN 418
             +S   P  YA+RF  F+ N
Sbjct: 414 DTVSVHRPGFYAERFQRFMCN 434


>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
           isoform 2 [Homo sapiens]
          Length = 540

 Score =  162 bits (411), Expect = 4e-40
 Identities = 128/415 (30%), Positives = 192/415 (46%), Gaps = 32/415 (7%)

Query: 12  SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
           SAA  G   PG     KT KK           A+  + G    G+ +++  L+  P   +
Sbjct: 3   SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52

Query: 71  LLPDDFKASSKI--KVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTR 128
           L+ D +   S       ++L    + P  F+FK Y P  FR  R+ FGI   DYL S+  
Sbjct: 53  LMQDFYVVESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICS 111

Query: 129 NPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQF 185
            P  E  + G+ G  F ++ D   +IK V  ++   +   L  Y+  + + +  TLLP+F
Sbjct: 112 EPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKF 170

Query: 186 LGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDF 245
            G+Y +     +  ++VM N+    + +H  YDLKGS   R AS KE+ K  PT KD+DF
Sbjct: 171 YGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDF 230

Query: 246 L-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVR 303
           L + ++ +Y   E     ++ L+RD   L   KIMDYSLLLGIH +     E EEE P  
Sbjct: 231 LQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQN 290

Query: 304 EDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAP 363
             +++  G   +    A+    G    G G    +   +G            I +     
Sbjct: 291 VPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRG 339

Query: 364 QKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 418
           +K + FMG+IDIL  Y   KK  H+ K + +  G  +S   P  YA RFL F+ +
Sbjct: 340 EKLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393


>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 3 [Homo sapiens]
          Length = 522

 Score =  138 bits (347), Expect = 1e-32
 Identities = 117/381 (30%), Positives = 166/381 (43%), Gaps = 55/381 (14%)

Query: 47  LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENL-PSH----FKFK 101
           L G    G+ H++  LS  P   +L+ D +   S    +       NL P+H    F+FK
Sbjct: 73  LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEG----SNLTPAHHYNDFRFK 128

Query: 102 EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSED 158
            Y P  FR  R+ FGI   DYL SL   P  E  S G+ G  F +S D   +IK V  ++
Sbjct: 129 TYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKE 188

Query: 159 IADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
              +   L  Y+  + + +  TLLP+F G+Y V    ++  ++VM N+    + +H KYD
Sbjct: 189 AEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYD 247

Query: 219 LKGSLVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLK 277
           LKGS   R AS KE+ K LPT KD+DFL      +++  +      + L+RD   L   K
Sbjct: 248 LKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFK 307

Query: 278 IMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIH 337
           IMDYSLL+ IH+I       + A      SE         P      Y T+ E I G   
Sbjct: 308 IMDYSLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG--- 357

Query: 338 SHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
                                       E    G ++   Q+   KK  H+ K + H  G
Sbjct: 358 ----------------------------EARRGGTMETDDQF--VKKLEHSWKALVHD-G 386

Query: 398 AEISTVHPEQYAKRFLDFITN 418
             +S   P  YA+RF  F+ N
Sbjct: 387 DTVSVHRPGFYAERFQRFMCN 407


>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 1 [Homo sapiens]
          Length = 394

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 84/315 (26%), Positives = 146/315 (46%), Gaps = 36/315 (11%)

Query: 108 FRNLRDRFGIDDQDYLVSLTRNPPS----ESEGSDGRFLISYDRTLVIKEVSSEDIADMH 163
           F  LR   G+ ++DY  +L    P      +  S   F +S+D+   +K     ++  + 
Sbjct: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164

Query: 164 SNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGS 222
           ++L  Y Q++ + H ++LL + LG++ + VD  + +Y +VM+++F     +  +YD+KG 
Sbjct: 165 AHLPRYVQHLQR-HPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223

Query: 223 LVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 281
            VSR      +   L   LKD++F  K   + +G + +  FL +++ D  FL +L ++DY
Sbjct: 224 EVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDY 280

Query: 282 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 341
           SLL+                 R  E E     SL    A       SPE          P
Sbjct: 281 SLLIAFQ--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLP 326

Query: 342 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 401
             P          A+   +G  Q+  YF+G++D+ T Y  +K+  H  KT+++  G   S
Sbjct: 327 DAPN---------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFS 374

Query: 402 TVHPEQYAKRFLDFI 416
           TV P +YA+R   ++
Sbjct: 375 TVSPARYARRLCQWV 389


>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 2 [Homo sapiens]
          Length = 191

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 59/215 (27%), Positives = 95/215 (44%), Gaps = 30/215 (13%)

Query: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKI 261
           M+++F     +  +YD+KG  VSR      +   L   LKD++F  K   + +G + +  
Sbjct: 1   MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSW 57

Query: 262 FLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPAL 321
           FL +++ D  FL +L ++DYSLL+                 R  E E     SL    A 
Sbjct: 58  FLRQMELDTTFLRELNVLDYSLLIAFQ--------------RLHEDERGPGSSLIFRTAR 103

Query: 322 VGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDA 381
                 SPE          P  P          A+   +G  Q+  YF+G++D+ T Y  
Sbjct: 104 SVQGAQSPEESRAQNRRLLPDAPN---------ALHILDGPEQR--YFLGVVDLATVYGL 152

Query: 382 KKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFI 416
           +K+  H  KT+++  G   STV P +YA+R   ++
Sbjct: 153 RKRLEHLWKTLRY-PGRTFSTVSPARYARRLCQWV 186


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
            isoform 2 [Homo sapiens]
          Length = 2098

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 52/185 (28%), Positives = 88/185 (47%), Gaps = 15/185 (8%)

Query: 119  DQDYLVSLTRNPPSESEG--SDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYI--- 173
            ++D++ SL+ + P ++ G  S   F  + D   ++K++   ++        +Y  YI   
Sbjct: 1842 EEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNA 1901

Query: 174  VKCHGNTLLPQFLGMYRVSVDNEDSY------MLVMRNMFSHRLPVHRKYDLKGSLVSRE 227
            V+    T L + LG+YR+   N  +       +LVM N+F  R  + + +DLKGSL +R 
Sbjct: 1902 VQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRN 1960

Query: 228  A-SDKEKVKELPTLKDMDFLN--KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLL 284
              +D  K      L D + L   ++  +YI    K +    +  D  FL    I+DYSLL
Sbjct: 1961 VKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLL 2020

Query: 285  LGIHD 289
            +G  D
Sbjct: 2021 VGRDD 2025


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score = 32.7 bits (73), Expect = 0.63
 Identities = 26/93 (27%), Positives = 36/93 (38%), Gaps = 17/93 (18%)

Query: 303 REDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGA 362
           RED+ +VD          L G+YG+SP    G   +  P  P E E          A+G 
Sbjct: 77  REDDEDVD---------QLFGAYGSSPGPSPGPSPARPPAKPPEDEP--------DADGY 119

Query: 363 PQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHG 395
              +   +G +D    YD +  A H   T   G
Sbjct: 120 ESDDCTALGTLDFSLLYDQENNALHCTITKAKG 152


>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
          Length = 828

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 41/188 (21%), Positives = 75/188 (39%), Gaps = 13/188 (6%)

Query: 11  VSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
           V+AA A PG G   AS  +K H++    +         G+  W + ++I+E ++     M
Sbjct: 15  VAAAGAQPGSGENTASVLQKDHYLDSSWRTEN------GLIPWTLDNTISEENRAVIEKM 68

Query: 71  LLPDDFKASSKIKVNN-HLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRN 129
           LL +++  S K +     L  +E+   + K  +   ++  +   +       Y V  T  
Sbjct: 69  LLEEEYYLSKKSQPEKVWLDQKEDDKKYMKSLQKTAKIMVHSPTK----PASYSVKWTIE 124

Query: 130 PPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMY 189
                E    +F   +  T + K + S  +  + S    Y +  VKC  +   P     +
Sbjct: 125 EKELFEQGLAKFGRRW--TKISKLIGSRTVLQVKSYARQYFKNKVKCGLDKETPNQKTGH 182

Query: 190 RVSVDNED 197
            + V NED
Sbjct: 183 NLQVKNED 190


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 236
           L+P++L   R  VD+ED  + + R M   S  L V RK  +K    L S  A DKE  K 
Sbjct: 369 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYK- 427

Query: 237 LPTLKDMDFLNKNQKVYIGEE 257
               K  +  +KN K+ I E+
Sbjct: 428 ----KFYEAFSKNLKLGIHED 444


>gi|29789078 UDP glycosyltransferase 1 family, polypeptide A10
           precursor [Homo sapiens]
          Length = 530

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 13/67 (19%)

Query: 50  VFLWGV-AHSINELSQVPPPVMLLPDDFKASS-----KIKVNNHLFHRENLPSHFKFKEY 103
           VF  G+  H + E +Q P P+  +P+D    S     K +V NH+ H E+   H     +
Sbjct: 167 VFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLED---HL----F 219

Query: 104 CPQVFRN 110
           C  +FRN
Sbjct: 220 CQYLFRN 226


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 236
           L+P++L   R  VD+ED  + + R M   S  L V RK  +K    L +  A DKE  K 
Sbjct: 377 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 435

Query: 237 LPTLKDMDFLNKNQKVYIGEEEK 259
               K  +  +KN K+ I E+ +
Sbjct: 436 ----KFYEQFSKNIKLGIHEDSQ 454


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)

Query: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 236
           L+P++L   R  VD+ED  + + R M   S  L V RK  +K    L +  A DKE  K 
Sbjct: 499 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 557

Query: 237 LPTLKDMDFLNKNQKVYIGEEEK 259
               K  +  +KN K+ I E+ +
Sbjct: 558 ----KFYEQFSKNIKLGIHEDSQ 576


>gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo
           sapiens]
          Length = 169

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 201 LVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKK 260
           LV+R   S RLPV R    +GS    E S   +   L + K+ D   +  K+   EE+ K
Sbjct: 54  LVLRRDSSQRLPVARPRRSRGS----ENSHSSQSFHLASNKNRDIFAEALKIQESEEKVK 109

Query: 261 IFLEKLKRDVEFLVQLK 277
            +L+K K   E L  L+
Sbjct: 110 -YLQKAKTREEILQLLR 125


>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
          Length = 595

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (6%)

Query: 249 NQKVYIGEEEKKIFLEK----LKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVRE 304
           ++K+ + E ++K F E     +K++ E + QL+    +L L + D+++G E   +A +RE
Sbjct: 75  HKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLDLLKGDEKVVQAVIRE 134


>gi|50053795 eukaryotic translation initiation factor 4B [Homo
           sapiens]
          Length = 611

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 4/41 (9%)

Query: 294 SEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGG 334
           ++P EE P R+DE++VDG   +  P    G+    P G GG
Sbjct: 515 AQPSEEGPGRKDENKVDG---MNAPKGQTGNSSRGP-GDGG 551


>gi|4758220 XAP-5 protein [Homo sapiens]
          Length = 339

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 15/93 (16%)

Query: 227 EASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF-----------LEKLKRDVEFLVQ 275
           EA  K     L TL DM      Q+  + E EK++            LEKL R+ E   +
Sbjct: 57  EAELKSSTVGLVTLNDM---KAKQEALVKEREKQLAKKEQSKELQMKLEKL-REKERKKE 112

Query: 276 LKIMDYSLLLGIHDIIRGSEPEEEAPVREDESE 308
            K    SL   + +   G E EEEA + E+E E
Sbjct: 113 AKRKISSLSFTLEEEEEGGEEEEEAAMYEEEME 145


>gi|145580615 KRI1 homolog [Homo sapiens]
          Length = 709

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 15/45 (33%), Positives = 22/45 (48%)

Query: 287 IHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEG 331
           + D I     EEE    EDE E++ +  + GPP  +    +S EG
Sbjct: 246 LRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEG 290


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 14/54 (25%), Positives = 28/54 (51%)

Query: 212 PVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEK 265
           P   +   + S    E+SD+E+ ++LP  +  +   + +K Y G+  KK  ++K
Sbjct: 126 PAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKK 179


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 14/115 (12%)

Query: 7   PPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQV- 65
           PP T+S A    G G    S+    H + ++V++     P V      V  S ++ S V 
Sbjct: 623 PPPTLSPAAITVGRGEDLTSE----HPLLEQVEL-----PAVASVSASVIKSPSDPSHVS 673

Query: 66  -PPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDD 119
            PPP +LLP     S+   +++ +   EN P     K   PQ+  ++ + F I +
Sbjct: 674 VPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVK---PQILTHVIEGFVIQE 725


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,279,291
Number of Sequences: 37866
Number of extensions: 817768
Number of successful extensions: 2653
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2599
Number of HSP's gapped (non-prelim): 34
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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