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Search of human proteins with 225579065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225579065 solute carrier family 12, member 4 isoform d [Homo
sapiens]
(1079 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225579065 solute carrier family 12, member 4 isoform d [Homo ... 2165 0.0
gi|4827006 solute carrier family 12, member 4 isoform a [Homo sa... 2100 0.0
gi|225579067 solute carrier family 12, member 4 isoform e [Homo ... 2098 0.0
gi|225579061 solute carrier family 12, member 4 isoform b [Homo ... 2083 0.0
gi|225579063 solute carrier family 12, member 4 isoform c [Homo ... 2032 0.0
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 1665 0.0
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 1665 0.0
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 1665 0.0
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 1665 0.0
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 1665 0.0
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 1664 0.0
gi|198041678 solute carrier family 12 (potassium-chloride transp... 1506 0.0
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 1506 0.0
gi|123701900 solute carrier family 12 (potassium/chloride transp... 1503 0.0
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 264 4e-70
gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo ... 234 3e-61
gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo ... 231 4e-60
gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo ... 231 4e-60
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 231 4e-60
gi|134254459 sodium potassium chloride cotransporter 2 [Homo sap... 212 1e-54
gi|38569457 solute carrier family 12, member 8 [Homo sapiens] 102 3e-21
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 51 7e-06
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 47 7e-05
gi|114326550 solute carrier family 7 (cationic amino acid transp... 39 0.020
gi|114326544 solute carrier family 7 (cationic amino acid transp... 39 0.020
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 38 0.045
gi|10947061 adenylate cyclase 6 isoform b [Homo sapiens] 37 0.077
gi|181337167 solute carrier family 7 (cationic amino acid transp... 36 0.17
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 35 0.29
gi|4758646 kinesin family member 3B [Homo sapiens] 35 0.50
>gi|225579065 solute carrier family 12, member 4 isoform d [Homo
sapiens]
Length = 1079
Score = 2165 bits (5609), Expect = 0.0
Identities = 1079/1079 (100%), Positives = 1079/1079 (100%)
Query: 1 MAAEGAVCGFVYLEGTAWAVPEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDRNL 60
MAAEGAVCGFVYLEGTAWAVPEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDRNL
Sbjct: 1 MAAEGAVCGFVYLEGTAWAVPEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDRNL 60
Query: 61 ALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYL 120
ALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYL
Sbjct: 61 ALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYL 120
Query: 121 PCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSY 180
PCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSY
Sbjct: 121 PCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSY 180
Query: 181 FMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNA 240
FMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNA
Sbjct: 181 FMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNA 240
Query: 241 TLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFP 300
TLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFP
Sbjct: 241 TLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFP 300
Query: 301 VCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIP 360
VCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIP
Sbjct: 301 VCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIP 360
Query: 361 GIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGI 420
GIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGI
Sbjct: 361 GIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGI 420
Query: 421 FFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKY 480
FFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKY
Sbjct: 421 FFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKY 480
Query: 481 GDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFG 540
GDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFG
Sbjct: 481 GDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFG 540
Query: 541 HGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPN 600
HGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPN
Sbjct: 541 HGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPN 600
Query: 601 WRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIR 660
WRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIR
Sbjct: 601 WRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIR 660
Query: 661 GLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTI 720
GLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTI
Sbjct: 661 GLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTI 720
Query: 721 VGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGM 780
VGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGM
Sbjct: 721 VGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGM 780
Query: 781 RHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHI 840
RHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHI
Sbjct: 781 RHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHI 840
Query: 841 DVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEA 900
DVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEA
Sbjct: 841 DVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEA 900
Query: 901 EVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLY 960
EVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLY
Sbjct: 901 EVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLY 960
Query: 961 SDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLN 1020
SDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLN
Sbjct: 961 SDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLN 1020
Query: 1021 EVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
EVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS
Sbjct: 1021 EVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
>gi|4827006 solute carrier family 12, member 4 isoform a [Homo
sapiens]
Length = 1085
Score = 2100 bits (5442), Expect = 0.0
Identities = 1052/1067 (98%), Positives = 1054/1067 (98%), Gaps = 1/1067 (0%)
Query: 13 LEGTAWAVPEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPK 72
LEG +W + L GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPK
Sbjct: 20 LEGLSWVDYGERAELDDSD-GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPK 78
Query: 73 VSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILF 132
VSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILF
Sbjct: 79 VSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILF 138
Query: 133 LRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFG 192
LRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFG
Sbjct: 139 LRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFG 198
Query: 193 GAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIF 252
GAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIF
Sbjct: 199 GAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIF 258
Query: 253 LTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRD 312
LTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRD
Sbjct: 259 LTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRD 318
Query: 313 QFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQE 372
QFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQE
Sbjct: 319 QFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQE 378
Query: 373 NLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGS 432
NLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGS
Sbjct: 379 NLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGS 438
Query: 433 NRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGT 492
NRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGT
Sbjct: 439 NRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGT 498
Query: 493 LAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWAL 552
LAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWAL
Sbjct: 499 LAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWAL 558
Query: 553 LLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWAL 612
LLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWAL
Sbjct: 559 LLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWAL 618
Query: 613 SFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALL 672
SFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALL
Sbjct: 619 SFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALL 678
Query: 673 RLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 732
RLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES
Sbjct: 679 RLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 738
Query: 733 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYG 792
YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYG
Sbjct: 739 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYG 798
Query: 793 WRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGML 852
WRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGML
Sbjct: 799 WRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGML 858
Query: 853 MLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDI 912
MLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDI
Sbjct: 859 MLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDI 918
Query: 913 SAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGAD 972
SAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGAD
Sbjct: 919 SAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGAD 978
Query: 973 KIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARL 1032
KIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARL
Sbjct: 979 KIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARL 1038
Query: 1033 VLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
VLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS
Sbjct: 1039 VLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1085
>gi|225579067 solute carrier family 12, member 4 isoform e [Homo
sapiens]
Length = 1054
Score = 2098 bits (5437), Expect = 0.0
Identities = 1047/1047 (100%), Positives = 1047/1047 (100%)
Query: 33 GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKE 92
GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKE
Sbjct: 8 GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKE 67
Query: 93 HEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVL 152
HEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVL
Sbjct: 68 HEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVL 127
Query: 153 ICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYIL 212
ICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYIL
Sbjct: 128 ICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYIL 187
Query: 213 GAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFAS 272
GAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFAS
Sbjct: 188 GAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFAS 247
Query: 273 LFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQL 332
LFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQL
Sbjct: 248 LFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQL 307
Query: 333 WSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPS 392
WSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPS
Sbjct: 308 WSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPS 367
Query: 393 ADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILA 452
ADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILA
Sbjct: 368 ADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILA 427
Query: 453 IITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGA 512
IITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGA
Sbjct: 428 IITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGA 487
Query: 513 GLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVA 572
GLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVA
Sbjct: 488 GLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVA 547
Query: 573 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYA 632
PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYA
Sbjct: 548 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYA 607
Query: 633 LVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLL 692
LVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLL
Sbjct: 608 LVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLL 667
Query: 693 KLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKV 752
KLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKV
Sbjct: 668 KLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKV 727
Query: 753 KGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCT 812
KGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCT
Sbjct: 728 KGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCT 787
Query: 813 TAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRI 872
TAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRI
Sbjct: 788 TAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRI 847
Query: 873 FTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQ 932
FTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQ
Sbjct: 848 FTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQ 907
Query: 933 MRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSH 992
MRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSH
Sbjct: 908 MRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSH 967
Query: 993 APDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYME 1052
APDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYME
Sbjct: 968 APDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYME 1027
Query: 1053 FLEVLTEGLERVLLVRGGGREVITIYS 1079
FLEVLTEGLERVLLVRGGGREVITIYS
Sbjct: 1028 FLEVLTEGLERVLLVRGGGREVITIYS 1054
>gi|225579061 solute carrier family 12, member 4 isoform b [Homo
sapiens]
Length = 1079
Score = 2083 bits (5398), Expect = 0.0
Identities = 1046/1067 (98%), Positives = 1048/1067 (98%), Gaps = 7/1067 (0%)
Query: 13 LEGTAWAVPEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPK 72
LEG +W + L GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPK
Sbjct: 20 LEGLSWVDYGERAELDDSD-GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPK 78
Query: 73 VSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILF 132
VSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILF
Sbjct: 79 VSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILF 138
Query: 133 LRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFG 192
LRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFG
Sbjct: 139 LRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFG 198
Query: 193 GAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIF 252
GAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIF
Sbjct: 199 GAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIF 258
Query: 253 LTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRD 312
LTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRD
Sbjct: 259 LTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRD 318
Query: 313 QFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQE 372
QFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQE
Sbjct: 319 QFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQE 378
Query: 373 NLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGS 432
NLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGS
Sbjct: 379 NLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGS 438
Query: 433 NRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGT 492
NRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGT
Sbjct: 439 NRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGT 498
Query: 493 LAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWAL 552
LAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWAL
Sbjct: 499 LAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWAL 558
Query: 553 LLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWAL 612
LLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWAL
Sbjct: 559 LLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWAL 618
Query: 613 SFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALL 672
SFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALL
Sbjct: 619 SFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALL 678
Query: 673 RLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 732
RLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES
Sbjct: 679 RLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 738
Query: 733 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYG 792
YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYG
Sbjct: 739 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYG 798
Query: 793 WRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGML 852
WRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGML
Sbjct: 799 WRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGML 858
Query: 853 MLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDI 912
MLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAE HNSDI
Sbjct: 859 MLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAE------HNSDI 912
Query: 913 SAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGAD 972
SAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGAD
Sbjct: 913 SAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGAD 972
Query: 973 KIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARL 1032
KIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARL
Sbjct: 973 KIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARL 1032
Query: 1033 VLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
VLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS
Sbjct: 1033 VLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
>gi|225579063 solute carrier family 12, member 4 isoform c [Homo
sapiens]
Length = 1087
Score = 2032 bits (5265), Expect = 0.0
Identities = 1015/1015 (100%), Positives = 1015/1015 (100%)
Query: 65 EELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQ 124
EELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQ
Sbjct: 73 EELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQ 132
Query: 125 NIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMIS 184
NIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMIS
Sbjct: 133 NIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMIS 192
Query: 185 RSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNN 244
RSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNN
Sbjct: 193 RSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNN 252
Query: 245 MRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCML 304
MRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCML
Sbjct: 253 MRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCML 312
Query: 305 GNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPG 364
GNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPG
Sbjct: 313 GNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPG 372
Query: 365 AAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPS 424
AAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPS
Sbjct: 373 AAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPS 432
Query: 425 VTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGV 484
VTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGV
Sbjct: 433 VTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGV 492
Query: 485 SRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKV 544
SRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKV
Sbjct: 493 SRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKV 552
Query: 545 NGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPR 604
NGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPR
Sbjct: 553 NGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPR 612
Query: 605 FKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSL 664
FKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSL
Sbjct: 613 FKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSL 672
Query: 665 SAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSV 724
SAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSV
Sbjct: 673 SAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSV 732
Query: 725 IQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNS 784
IQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNS
Sbjct: 733 IQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNS 792
Query: 785 VVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWW 844
VVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWW
Sbjct: 793 VVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWW 852
Query: 845 IVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEV 904
IVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEV
Sbjct: 853 IVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEV 912
Query: 905 VEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEE 964
VEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEE
Sbjct: 913 VEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEE 972
Query: 965 DESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIV 1024
DESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIV
Sbjct: 973 DESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIV 1032
Query: 1025 TRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
TRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS
Sbjct: 1033 TRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1087
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 96 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 155
Query: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 156 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 215
Query: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 216 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 275
Query: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 276 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 335
Query: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 336 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 395
Query: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 396 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 452
Query: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 453 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 512
Query: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 513 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 572
Query: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 573 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 632
Query: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 633 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 692
Query: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 693 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 752
Query: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 753 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 812
Query: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 813 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 872
Query: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 873 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 932
Query: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 933 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 992
Query: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 993 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1052
Query: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 1053 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1112
Query: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1113 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1141
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 46 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 105
Query: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 106 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 165
Query: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 166 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 225
Query: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 226 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 285
Query: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 286 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 345
Query: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 346 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 402
Query: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 403 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 462
Query: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 463 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 522
Query: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 523 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 582
Query: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 583 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 642
Query: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 643 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 702
Query: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 703 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 762
Query: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 763 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 822
Query: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 823 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 882
Query: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 883 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 942
Query: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 943 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1002
Query: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 1003 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1062
Query: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1063 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 46 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 105
Query: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 106 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 165
Query: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 166 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 225
Query: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 226 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 285
Query: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 286 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 345
Query: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 346 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 402
Query: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 403 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 462
Query: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 463 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 522
Query: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 523 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 582
Query: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 583 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 642
Query: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 643 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 702
Query: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 703 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 762
Query: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 763 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 822
Query: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 823 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 882
Query: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 883 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 942
Query: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 943 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1002
Query: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 1003 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1062
Query: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1063 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 54 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 113
Query: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 114 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 173
Query: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 174 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 233
Query: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 234 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 293
Query: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 294 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 353
Query: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 354 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 410
Query: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 411 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 470
Query: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 471 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 530
Query: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 531 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 590
Query: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 591 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 650
Query: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 651 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 710
Query: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 711 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 770
Query: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 771 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 830
Query: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 831 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 890
Query: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 891 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 950
Query: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 951 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1010
Query: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 1011 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1070
Query: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1071 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1099
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 105 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 164
Query: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 165 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 224
Query: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 225 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 284
Query: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 285 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 344
Query: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 345 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 404
Query: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 405 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 461
Query: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 462 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 521
Query: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 522 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 581
Query: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 582 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 641
Query: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 642 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 701
Query: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 702 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 761
Query: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 762 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 821
Query: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 822 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 881
Query: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 882 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 941
Query: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 942 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 1001
Query: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 1002 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1061
Query: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 1062 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1121
Query: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1122 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1150
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 1664 bits (4310), Expect = 0.0
Identities = 820/1046 (78%), Positives = 924/1046 (88%), Gaps = 4/1046 (0%)
Query: 35 GNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHE 94
G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAKEHE
Sbjct: 93 GHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHE 152
Query: 95 EAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLIC 154
EAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IVLIC
Sbjct: 153 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 212
Query: 155 CCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGA 214
CCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYILGA
Sbjct: 213 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 272
Query: 215 IEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 274
IEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFASLF
Sbjct: 273 IEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 332
Query: 275 LACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWS 334
LACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++LW
Sbjct: 333 LACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWG 392
Query: 335 FFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSAD 394
FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK PSA
Sbjct: 393 FFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSAK 449
Query: 395 APSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAI 453
+ + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTILAI
Sbjct: 450 SSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAI 509
Query: 454 ITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAG 513
+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTCGAG
Sbjct: 510 LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAG 569
Query: 514 LQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAP 573
LQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+VAP
Sbjct: 570 LQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAP 629
Query: 574 ILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYAL 633
ILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWYYA+
Sbjct: 630 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAI 689
Query: 634 VAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLK 693
VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVLLK
Sbjct: 690 VAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLK 749
Query: 694 LDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVK 753
LDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME EKVK
Sbjct: 750 LDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVK 809
Query: 754 GFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTT 813
GFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR TT
Sbjct: 810 GFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTT 869
Query: 814 AAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIF 873
AAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RIF
Sbjct: 870 AAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIF 929
Query: 874 TVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQM 933
TVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQMLR M
Sbjct: 930 TVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHM 989
Query: 934 RLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHA 993
RL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM + +
Sbjct: 990 RLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKS 1049
Query: 994 PDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEF 1053
+ F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENYMEF
Sbjct: 1050 MEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEF 1109
Query: 1054 LEVLTEGLERVLLVRGGGREVITIYS 1079
LEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1110 LEVLTEGLERVLLVRGGGSEVITIYS 1135
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 1506 bits (3898), Expect = 0.0
Identities = 760/1101 (69%), Positives = 883/1101 (80%), Gaps = 56/1101 (5%)
Query: 33 GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKE 92
G GN +ESSPF++ + +G +Y +N+ALFEEE+D P VSSLL L +YTNL QG++E
Sbjct: 41 GDGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSRE 100
Query: 93 HEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVL 152
HEEAE+ EG +++ +AP MGT MGVYLPCLQNIFGVILFLRLTW+VG AG++++ +V
Sbjct: 101 HEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVF 160
Query: 153 ICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYIL 212
ICC CT+LTAISMSAIATNGVVPAGGSY+MISRSLGPEFGGAVGLCFYLGTTFA AMYIL
Sbjct: 161 ICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYIL 220
Query: 213 GAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFAS 272
G IEILL Y+ P AIF A + A LNNMRVYGT LT M VVFVGVKYVNKFA
Sbjct: 221 GTIEILLAYLFPAMAIFKAEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFAL 280
Query: 273 LFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQL 332
+FL CVI+SIL+IYAG IKS FDPP FP+C+LGNRTLSR FD+CAK A NETV T+L
Sbjct: 281 VFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRL 340
Query: 333 WSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPS 392
W FC S L +CD YF NNVTEI GIPGAA+G+++ENLWS+YL KG IVE+ G+ S
Sbjct: 341 WGLFCSSRFLNA-TCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTS 399
Query: 393 ---ADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGT 449
AD + P YV +D+ + FT+LVGI+FPSVTGIMAGSNRSGDLRDAQKSIP GT
Sbjct: 400 VGLADGTPIDMDHP-YVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGT 458
Query: 450 ILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFST 509
ILAI TTS VY SSVVLFGACIEGVVLRDK+G+ V+ NLVVGTLAWPSPWVIVIGSFFST
Sbjct: 459 ILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFST 518
Query: 510 CGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLD 569
CGAGLQSLTGAPRLLQAI++D I+PFL+VFGHGK NGEPTWALLLTA I E+GILIASLD
Sbjct: 519 CGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLD 578
Query: 570 MVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSW 629
VAPILSMFFLMCY+FVNLACAVQTLLRTPNWRPRF+YYHW LSFLGMSLCLALMF+ SW
Sbjct: 579 EVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSW 638
Query: 630 YYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLL 689
YYALVAMLIAG+IYKYIEY+GAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLL
Sbjct: 639 YYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLL 698
Query: 690 VLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEI 749
VL+++D+D +V +P+LL+ SQLKAGKGLTIVGSV++G+FLE++ +AQ AE++I+ +ME
Sbjct: 699 VLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEA 758
Query: 750 EKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTV 809
EKVKGFCQVV++S +R+G++HLIQS GLGG++HN+V++GWP WRQ ED + W+ FI+ V
Sbjct: 759 EKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELV 818
Query: 810 RCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCR 869
R TTA HLALLV KN++ +P N ER+ EG IDVWWIVHDGGMLMLLPFLLR HKVWRKC+
Sbjct: 819 RETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCK 878
Query: 870 MRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQM 929
MRIFTVAQMDDNSIQMKKDL FLYHLR+ AEVEVVEMH SDISAYTYE+TL+MEQRSQ+
Sbjct: 879 MRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQI 938
Query: 930 LRQMRLTKTEREREAQLVKDR-----------HSALRL---ESLYSDEED---------- 965
L+QM LTK ERERE Q + D ++ LRL E D E+
Sbjct: 939 LKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDSEEKPEEEVQLIH 998
Query: 966 --------------------ESAVGADKIQMTWTRDKYMTE-TWDPSH-APDNFRELVHI 1003
E +K+ +TWT+DK + E PS + + ++ +
Sbjct: 999 DQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSM 1058
Query: 1004 KPD-----QSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLT 1058
KP+ QSNVRRMHTAV+LNEVIV +S DA+LVLLNMPGPPRN GDENYMEFLEVLT
Sbjct: 1059 KPEWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLT 1118
Query: 1059 EGLERVLLVRGGGREVITIYS 1079
E L+RV+LVRGGGREVITIYS
Sbjct: 1119 EHLDRVMLVRGGGREVITIYS 1139
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 1506 bits (3898), Expect = 0.0
Identities = 760/1101 (69%), Positives = 883/1101 (80%), Gaps = 56/1101 (5%)
Query: 33 GHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKE 92
G GN +ESSPF++ + +G +Y +N+ALFEEE+D P VSSLL L +YTNL QG++E
Sbjct: 18 GDGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSRE 77
Query: 93 HEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVL 152
HEEAE+ EG +++ +AP MGT MGVYLPCLQNIFGVILFLRLTW+VG AG++++ +V
Sbjct: 78 HEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVF 137
Query: 153 ICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYIL 212
ICC CT+LTAISMSAIATNGVVPAGGSY+MISRSLGPEFGGAVGLCFYLGTTFA AMYIL
Sbjct: 138 ICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYIL 197
Query: 213 GAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFAS 272
G IEILL Y+ P AIF A + A LNNMRVYGT LT M VVFVGVKYVNKFA
Sbjct: 198 GTIEILLAYLFPAMAIFKAEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFAL 257
Query: 273 LFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQL 332
+FL CVI+SIL+IYAG IKS FDPP FP+C+LGNRTLSR FD+CAK A NETV T+L
Sbjct: 258 VFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRL 317
Query: 333 WSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPS 392
W FC S L +CD YF NNVTEI GIPGAA+G+++ENLWS+YL KG IVE+ G+ S
Sbjct: 318 WGLFCSSRFLNA-TCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTS 376
Query: 393 ---ADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGT 449
AD + P YV +D+ + FT+LVGI+FPSVTGIMAGSNRSGDLRDAQKSIP GT
Sbjct: 377 VGLADGTPIDMDHP-YVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGT 435
Query: 450 ILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFST 509
ILAI TTS VY SSVVLFGACIEGVVLRDK+G+ V+ NLVVGTLAWPSPWVIVIGSFFST
Sbjct: 436 ILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFST 495
Query: 510 CGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLD 569
CGAGLQSLTGAPRLLQAI++D I+PFL+VFGHGK NGEPTWALLLTA I E+GILIASLD
Sbjct: 496 CGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLD 555
Query: 570 MVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSW 629
VAPILSMFFLMCY+FVNLACAVQTLLRTPNWRPRF+YYHW LSFLGMSLCLALMF+ SW
Sbjct: 556 EVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSW 615
Query: 630 YYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLL 689
YYALVAMLIAG+IYKYIEY+GAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLL
Sbjct: 616 YYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLL 675
Query: 690 VLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEI 749
VL+++D+D +V +P+LL+ SQLKAGKGLTIVGSV++G+FLE++ +AQ AE++I+ +ME
Sbjct: 676 VLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEA 735
Query: 750 EKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTV 809
EKVKGFCQVV++S +R+G++HLIQS GLGG++HN+V++GWP WRQ ED + W+ FI+ V
Sbjct: 736 EKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELV 795
Query: 810 RCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCR 869
R TTA HLALLV KN++ +P N ER+ EG IDVWWIVHDGGMLMLLPFLLR HKVWRKC+
Sbjct: 796 RETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCK 855
Query: 870 MRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQM 929
MRIFTVAQMDDNSIQMKKDL FLYHLR+ AEVEVVEMH SDISAYTYE+TL+MEQRSQ+
Sbjct: 856 MRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQI 915
Query: 930 LRQMRLTKTEREREAQLVKDR-----------HSALRL---ESLYSDEED---------- 965
L+QM LTK ERERE Q + D ++ LRL E D E+
Sbjct: 916 LKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDSEEKPEEEVQLIH 975
Query: 966 --------------------ESAVGADKIQMTWTRDKYMTE-TWDPSH-APDNFRELVHI 1003
E +K+ +TWT+DK + E PS + + ++ +
Sbjct: 976 DQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSM 1035
Query: 1004 KPD-----QSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLT 1058
KP+ QSNVRRMHTAV+LNEVIV +S DA+LVLLNMPGPPRN GDENYMEFLEVLT
Sbjct: 1036 KPEWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLT 1095
Query: 1059 EGLERVLLVRGGGREVITIYS 1079
E L+RV+LVRGGGREVITIYS
Sbjct: 1096 EHLDRVMLVRGGGREVITIYS 1116
>gi|123701900 solute carrier family 12 (potassium/chloride
transporters), member 7 [Homo sapiens]
Length = 1083
Score = 1503 bits (3892), Expect = 0.0
Identities = 750/1062 (70%), Positives = 869/1062 (81%), Gaps = 12/1062 (1%)
Query: 21 PEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKL 80
PE EP G GN RE+SPFL+ +E + + +N+ALFEEE+D P VSSLL KL
Sbjct: 31 PEGPEPERPSP-GDGNPRENSPFLNNVEVEQESFFEGKNMALFEEEMDSNPMVSSLLNKL 89
Query: 81 VSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVG 140
+YTNL+QG EHEE E +RRR A+AP MGT +GVYLPCLQNI GVILFLRLTW+VG
Sbjct: 90 ANYTNLSQGVVEHEEDEE---SRRREAKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVG 146
Query: 141 TAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFY 200
AGVL++ LIV +CC CT+LTAISMSAIATNGVVPAGGSY+MISRSLGPEFGGAVGLCFY
Sbjct: 147 VAGVLESFLIVAMCCTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFY 206
Query: 201 LGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVV 260
LGTTFA AMYILG IEI LTYI+P AAIF A + A L+NMRVYGT L M LVV
Sbjct: 207 LGTTFAGAMYILGTIEIFLTYISPGAAIFQAEAAGGEAAAMLHNMRVYGTCTLVLMALVV 266
Query: 261 FVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKT 320
FVGVKYVNK A +FLACV++SIL+IYAG IKS FDPP PVC+LGNRTLSR FD C K
Sbjct: 267 FVGVKYVNKLALVFLACVVLSILAIYAGVIKSAFDPPDIPVCLLGNRTLSRRSFDACVKA 326
Query: 321 AVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLE 380
+ N + + LW FC+ + +CD YF+ NNVTEI GIPGAA+GV ENLWS Y
Sbjct: 327 YGIHNNSATSALWGLFCNGSQPSA-ACDEYFIQNNVTEIQGIPGAASGVFLENLWSTYAH 385
Query: 381 KGDIVEKHGLPSADAP--SLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDL 438
G VEK G+PS S +LP YV+ DIA SFT+LVGI+FPSVTGIMAGSNRSGDL
Sbjct: 386 AGAFVEKKGVPSVPVAEESRASALP-YVLTDIAASFTLLVGIYFPSVTGIMAGSNRSGDL 444
Query: 439 RDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSP 498
+DAQKSIP GTILAI+TTS +Y S +VLFGACIEGVVLRDK+G+ + NLV+G LAWPSP
Sbjct: 445 KDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSP 504
Query: 499 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALI 558
WVIVIGSFFSTCGAGLQSLTGAPRLLQAIA+D I+PFL+VFGHGK NGEPTWALLLT LI
Sbjct: 505 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLTVLI 564
Query: 559 AELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMS 618
E GILIASLD VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFK+YHW LSFLGMS
Sbjct: 565 CETGILIASLDSVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMS 624
Query: 619 LCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGP 678
LCLALMF+ SWYYAL AMLIAG IYKYIEY+GAEKEWGDGIRGLSL+AARYALLR+E GP
Sbjct: 625 LCLALMFICSWYYALSAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALLRVEHGP 684
Query: 679 PHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQA 738
PHTKNWRPQ+LV+L LD + VK+PRLL+F SQLKAGKGLTIVGSV++G++L+ + EAQ
Sbjct: 685 PHTKNWRPQVLVMLNLDAEQAVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHMEAQR 744
Query: 739 AEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSED 798
AE+ I+++M EK KGFCQ+VV+S +R+G++HLIQS GLGG++HN+V++ WP W+Q ++
Sbjct: 745 AEENIRSLMSTEKTKGFCQLVVSSSLRDGMSHLIQSAGLGGLKHNTVLMAWPASWKQEDN 804
Query: 799 PRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFL 858
P +WK F+DTVR TTAAH ALLV KN+ +P N ER+ GHIDVWWIVHDGGMLMLLPFL
Sbjct: 805 PFSWKNFVDTVRDTTAAHQALLVAKNVDSFPQNQERFGGGHIDVWWIVHDGGMLMLLPFL 864
Query: 859 LRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYE 918
LRQHKVWRKCRMRIFTVAQ+DDNSIQMKKDL +FLYHLR+ AEVEVVEM +DISA+TYE
Sbjct: 865 LRQHKVWRKCRMRIFTVAQVDDNSIQMKKDLQMFLYHLRISAEVEVVEMVENDISAFTYE 924
Query: 919 RTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTW 978
RTLMMEQRSQML+QM+L+K E+EREAQL+ DR++A + ++ DK+QMTW
Sbjct: 925 RTLMMEQRSQMLKQMQLSKNEQEREAQLIHDRNTASHTAAA---ARTQAPPTPDKVQMTW 981
Query: 979 TRDKYMTETW-DPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNM 1037
TR+K + E + + F++L +KPDQSNVRRMHTAVKLN V++ +S DA+LVLLNM
Sbjct: 982 TREKLIAEKYRSRDTSLSGFKDLFSMKPDQSNVRRMHTAVKLNGVVLNKSQDAQLVLLNM 1041
Query: 1038 PGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
PGPP+N +GDENYMEFLEVLTEGL RVLLVRGGGREVITIYS
Sbjct: 1042 PGPPKNRQGDENYMEFLEVLTEGLNRVLLVRGGGREVITIYS 1083
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 264 bits (674), Expect = 4e-70
Identities = 251/868 (28%), Positives = 391/868 (45%), Gaps = 167/868 (19%)
Query: 107 AEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMS 166
A A + T +GV +P + ++F +++FLR+ ++VG AG+LQAL ++L+ LT +S+
Sbjct: 32 ASARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVC 91
Query: 167 AIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPA 226
AIATNG V GG+YFMISR+LGPE GG++GL FYL + G LL +
Sbjct: 92 AIATNGAVQGGGAYFMISRTLGPEVGGSIGLMFYLAN-------VCGCAVSLLGLVESVL 144
Query: 227 AIFYPSGAHDTSNATLNNM-RVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSI 285
+F GA T + L + + YG L + SL L V
Sbjct: 145 DVF---GADATGPSGLRVLPQGYGWNLL----------------YGSLLLGLV------- 178
Query: 286 YAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTD 345
GG VC LG +R F T ++ + ++A+ L SF P
Sbjct: 179 --GG-----------VCTLGAGLYARASF----LTFLLVSGSLASVLISFVAVGPRDIRL 221
Query: 346 SCDPYFMLNNVTEIPG----IPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKES 401
+ P N + +P G + L++NL + Y E
Sbjct: 222 TPRPG---PNGSSLPPRFGHFTGFNSSTLKDNLGAGYAE--------------------D 258
Query: 402 LPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYF 461
V + A+ F VL F TGIMAG+N SG+L+D ++IP+GTI+A+ T VY
Sbjct: 259 YTTGAVMNFASVFAVL----FNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFVYV 314
Query: 462 SSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAP 521
L + +L++ YG + +L WP +++IG + + A + SL GA
Sbjct: 315 LLFFLSSFTCDRTLLQEDYGFFRAISL------WPP--LVLIGIYATALSASMSSLIGAS 366
Query: 522 RLLQAIAKDNIIPFLRVFGHGKV---NGEPTWALLLTALIAELGILIASLDMVAPILSMF 578
R+L A+A+D++ F + KV G P A+L + + +L +L L+ +A ++++F
Sbjct: 367 RILHALARDDL--FGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVF 424
Query: 579 FLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLI 638
+L+ Y V+L+C PN+RP F + W LG++ CL +MF+ S A ++L+
Sbjct: 425 YLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLL 484
Query: 639 AGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDL 698
G++ + +G WG + L R LLRL+ H K WRPQLL+L
Sbjct: 485 MGLLAALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLL------- 537
Query: 699 HVKYPR----LLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQ--TIKNMMEIEKV 752
V PR LL A+QLK G GL ++G V G L+S Q ++++ +V
Sbjct: 538 -VGNPRGALPLLRLANQLKKG-GLYVLGHVTLGD-LDSLPSDPVQPQYGAWLSLVDRAQV 594
Query: 753 KGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGW----PYGWRQSEDPRAWKTFIDT 808
K F + ++ VR+G HL++ GLGGM+ N++VLG+ P DP A+ D+
Sbjct: 595 KAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDP-AFSEPADS 653
Query: 809 VRCTTAAHLALLVP---------------------------KNIAFYPSN----HERYLE 837
R ++ L+ L P KN+ ++ ER
Sbjct: 654 TREGSSPALSTLFPPPRAPGSPRALNPQDYVATVADALKMNKNVVLARASGALPPERLSR 713
Query: 838 G--------HIDVW------------WIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQ 877
G H+DVW ++ G L+ + +L W R+RIF
Sbjct: 714 GSGGTSQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLG 773
Query: 878 MDDNSIQMKKDLAVFLYHLRLEAEVEVV 905
+ + L L LR+ AEV+ V
Sbjct: 774 PREAPGAAEGRLRALLSQLRIRAEVQEV 801
>gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo
sapiens]
Length = 1021
Score = 234 bits (597), Expect = 3e-61
Identities = 195/739 (26%), Positives = 314/739 (42%), Gaps = 131/739 (17%)
Query: 413 SFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACI- 471
+F + IFFPS TGI+AG+N SGDL+D +IP GT++AI T++ Y + G+C+
Sbjct: 339 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVV 398
Query: 472 --EGVVLRDKY--GDGVSRNLVVG-----------------------TLAWPSPW--VIV 502
VL D G G L T++ S + +I
Sbjct: 399 RDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLIT 458
Query: 503 IGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALIAEL 561
G F +T + L L A ++ Q + +D + P + FG G N EP LL IA
Sbjct: 459 AGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVA 518
Query: 562 GILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCL 621
I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G + +
Sbjct: 519 FIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISV 578
Query: 622 ALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHT 681
+MF+ +W+ AL+A+ + + Y+ Y+ E WG ++ S + A + L E H
Sbjct: 579 VIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHI 638
Query: 682 KNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQ 741
KN+RPQ LVL P L+ F L I G V+ G + E Q
Sbjct: 639 KNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIAN 694
Query: 742 TIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRA 801
+ K+K F V+A +R G+ L+Q+ GLG M+ N +V+G+ W QS P
Sbjct: 695 GHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNW-QSAHPAT 753
Query: 802 WKTFIDTVR---------CTTAAHLALLVPK------NIAFYPSNHERYLEGH------- 839
+ +I + C L V K N F P+ +
Sbjct: 754 VEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVDPKALV 813
Query: 840 -----------------IDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNS 882
ID++W+ DGG+ +L+P+LL + + W KC++R+F Q+ +
Sbjct: 814 KEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQI-NRM 872
Query: 883 IQMKKDLAVFLYHLRLE-AEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTERE 941
Q +K + L RL EV ++ + + R
Sbjct: 873 DQERKAIISLLSKFRLGFHEVHILP---------------------------DINQNPRA 905
Query: 942 REAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTW-TRDKYMTETWDPSHAPDNFREL 1000
+ +D + RL + +DE+ V + W D+ +T+
Sbjct: 906 EHTKRFEDMIAPFRLNDGF---KDEATVNEMRRDCPWKISDEEITK-------------- 948
Query: 1001 VHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEG 1060
N + V+LNE+++ S DA L+++ +P + YM +LE L++
Sbjct: 949 --------NRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLSQD 1000
Query: 1061 LE-RVLLVRGGGREVITIY 1078
L V+L+RG V+T Y
Sbjct: 1001 LRPPVILIRGNQENVLTFY 1019
Score = 125 bits (315), Expect = 2e-28
Identities = 69/198 (34%), Positives = 111/198 (56%), Gaps = 17/198 (8%)
Query: 95 EAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLIC 154
E E+G + + E G + GV + C+ NI+GVIL+LRL W+ AG++ +I+L+
Sbjct: 119 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 178
Query: 155 CCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGA 214
T +T +S+SAI+TNG V +GG+YF+ISRSLGPE GG++GL F AM+ +G
Sbjct: 179 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 238
Query: 215 IE----ILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKF 270
E +L Y AP I P +N++R+ G + +T + + G+++ +K
Sbjct: 239 AETVRDLLQEYGAP---IVDP----------INDIRIIGVVSVTVLLAISLAGMEWESKA 285
Query: 271 ASLFLACVIISILSIYAG 288
LF +++S + G
Sbjct: 286 QVLFFLVIMVSFANYLVG 303
>gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo
sapiens]
Length = 1029
Score = 231 bits (588), Expect = 4e-60
Identities = 195/748 (26%), Positives = 314/748 (41%), Gaps = 140/748 (18%)
Query: 413 SFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACI- 471
+F + IFFPS TGI+AG+N SGDL+D +IP GT++AI T++ Y + G+C+
Sbjct: 338 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVV 397
Query: 472 --EGVVLRDKY--GDGVSRNLVVG-----------------------TLAWPSPW--VIV 502
VL D G G L T++ S + +I
Sbjct: 398 RDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLIT 457
Query: 503 IGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALIAEL 561
G F +T + L L A ++ Q + +D + P + FG G N EP LL IA
Sbjct: 458 AGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVA 517
Query: 562 GILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCL 621
I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G + +
Sbjct: 518 FIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISV 577
Query: 622 ALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHT 681
+MF+ +W+ AL+A+ + + Y+ Y+ E WG ++ S + A + L E H
Sbjct: 578 VIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHI 637
Query: 682 KNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQ 741
KN+RPQ LVL P L+ F L I G V+ G + E Q
Sbjct: 638 KNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIAN 693
Query: 742 TIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRA 801
+ K+K F V+A +R G+ L+Q+ GLG M+ N +V+G+ W QS P
Sbjct: 694 GHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNW-QSAHPAT 752
Query: 802 WKTFIDTVR---------CTTAAHLALLVPK------NIAFYPSNHERYLEGH------- 839
+ +I + C L V K N F P+ +
Sbjct: 753 VEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARGARPSVS 812
Query: 840 --------------------------IDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIF 873
ID++W+ DGG+ +L+P+LL + + W KC++R+F
Sbjct: 813 GALDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVF 872
Query: 874 TVAQMDDNSIQMKKDLAVFLYHLRLE-AEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQ 932
Q+ + Q +K + L RL EV ++
Sbjct: 873 VGGQI-NRMDQERKAIISLLSKFRLGFHEVHILP-------------------------- 905
Query: 933 MRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTW-TRDKYMTETWDPS 991
+ + R + +D + RL + +DE+ V + W D+ +T+
Sbjct: 906 -DINQNPRAEHTKRFEDMIAPFRLNDGF---KDEATVNEMRRDCPWKISDEEITK----- 956
Query: 992 HAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYM 1051
N + V+LNE+++ S DA L+++ +P + YM
Sbjct: 957 -----------------NRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYM 999
Query: 1052 EFLEVLTEGLE-RVLLVRGGGREVITIY 1078
+LE L++ L V+L+RG V+T Y
Sbjct: 1000 AWLETLSQDLRPPVILIRGNQENVLTFY 1027
Score = 125 bits (315), Expect = 2e-28
Identities = 69/198 (34%), Positives = 111/198 (56%), Gaps = 17/198 (8%)
Query: 95 EAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLIC 154
E E+G + + E G + GV + C+ NI+GVIL+LRL W+ AG++ +I+L+
Sbjct: 118 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 177
Query: 155 CCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGA 214
T +T +S+SAI+TNG V +GG+YF+ISRSLGPE GG++GL F AM+ +G
Sbjct: 178 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 237
Query: 215 IE----ILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKF 270
E +L Y AP I P +N++R+ G + +T + + G+++ +K
Sbjct: 238 AETVRDLLQEYGAP---IVDP----------INDIRIIGVVSVTVLLAISLAGMEWESKA 284
Query: 271 ASLFLACVIISILSIYAG 288
LF +++S + G
Sbjct: 285 QVLFFLVIMVSFANYLVG 302
>gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo
sapiens]
Length = 1030
Score = 231 bits (588), Expect = 4e-60
Identities = 195/748 (26%), Positives = 314/748 (41%), Gaps = 140/748 (18%)
Query: 413 SFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACI- 471
+F + IFFPS TGI+AG+N SGDL+D +IP GT++AI T++ Y + G+C+
Sbjct: 339 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVV 398
Query: 472 --EGVVLRDKY--GDGVSRNLVVG-----------------------TLAWPSPW--VIV 502
VL D G G L T++ S + +I
Sbjct: 399 RDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLIT 458
Query: 503 IGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALIAEL 561
G F +T + L L A ++ Q + +D + P + FG G N EP LL IA
Sbjct: 459 AGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVA 518
Query: 562 GILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCL 621
I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G + +
Sbjct: 519 FIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISV 578
Query: 622 ALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHT 681
+MF+ +W+ AL+A+ + + Y+ Y+ E WG ++ S + A + L E H
Sbjct: 579 VIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHI 638
Query: 682 KNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQ 741
KN+RPQ LVL P L+ F L I G V+ G + E Q
Sbjct: 639 KNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIAN 694
Query: 742 TIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRA 801
+ K+K F V+A +R G+ L+Q+ GLG M+ N +V+G+ W QS P
Sbjct: 695 GHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNW-QSAHPAT 753
Query: 802 WKTFIDTVR---------CTTAAHLALLVPK------NIAFYPSNHERYLEGH------- 839
+ +I + C L V K N F P+ +
Sbjct: 754 VEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARGARPSVS 813
Query: 840 --------------------------IDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIF 873
ID++W+ DGG+ +L+P+LL + + W KC++R+F
Sbjct: 814 GALDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVF 873
Query: 874 TVAQMDDNSIQMKKDLAVFLYHLRLE-AEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQ 932
Q+ + Q +K + L RL EV ++
Sbjct: 874 VGGQI-NRMDQERKAIISLLSKFRLGFHEVHILP-------------------------- 906
Query: 933 MRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTW-TRDKYMTETWDPS 991
+ + R + +D + RL + +DE+ V + W D+ +T+
Sbjct: 907 -DINQNPRAEHTKRFEDMIAPFRLNDGF---KDEATVNEMRRDCPWKISDEEITK----- 957
Query: 992 HAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYM 1051
N + V+LNE+++ S DA L+++ +P + YM
Sbjct: 958 -----------------NRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYM 1000
Query: 1052 EFLEVLTEGLE-RVLLVRGGGREVITIY 1078
+LE L++ L V+L+RG V+T Y
Sbjct: 1001 AWLETLSQDLRPPVILIRGNQENVLTFY 1028
Score = 125 bits (315), Expect = 2e-28
Identities = 69/198 (34%), Positives = 111/198 (56%), Gaps = 17/198 (8%)
Query: 95 EAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLIC 154
E E+G + + E G + GV + C+ NI+GVIL+LRL W+ AG++ +I+L+
Sbjct: 119 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 178
Query: 155 CCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGA 214
T +T +S+SAI+TNG V +GG+YF+ISRSLGPE GG++GL F AM+ +G
Sbjct: 179 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 238
Query: 215 IE----ILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKF 270
E +L Y AP I P +N++R+ G + +T + + G+++ +K
Sbjct: 239 AETVRDLLQEYGAP---IVDP----------INDIRIIGVVSVTVLLAISLAGMEWESKA 285
Query: 271 ASLFLACVIISILSIYAG 288
LF +++S + G
Sbjct: 286 QVLFFLVIMVSFANYLVG 303
>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
transporters), member 2 [Homo sapiens]
Length = 1212
Score = 231 bits (588), Expect = 4e-60
Identities = 148/420 (35%), Positives = 214/420 (50%), Gaps = 44/420 (10%)
Query: 413 SFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIE 472
+F + IFFP+ TGI+AG+N SGDL D Q +IP GT+LAI+ T+LVY V G+C
Sbjct: 486 TFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSC-- 543
Query: 473 GVVLRDKYGD---------------------------------GVSRNLVVGTLAWPSPW 499
V+RD G+ G+ N V ++
Sbjct: 544 --VVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTP 601
Query: 500 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVF--GHGKVNGEPTWALLLTAL 557
+I G F +T + L SL AP++ QA+ KDNI P ++F G+GK N EP +LT L
Sbjct: 602 LISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGK-NNEPLRGYILTFL 660
Query: 558 IAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGM 617
IA ILIA L+++API+S FFL Y +N + +L ++P WRP FKYY+ +S LG
Sbjct: 661 IALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLGA 720
Query: 618 SLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEG 677
LC +MFV +W+ AL+ +I +Y Y+ Y+ + WG + L+ A +RL
Sbjct: 721 ILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSGV 780
Query: 678 PPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQ 737
H KN+RPQ LV+ P LL GL I G V G ++ E
Sbjct: 781 EDHVKNFRPQCLVMTGAPN----SRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMS 836
Query: 738 AAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSE 797
+ + + K+K F V A +REG +L+Q+ GLG M+ N++VLG+ W Q++
Sbjct: 837 IDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQAD 896
Score = 130 bits (326), Expect = 9e-30
Identities = 76/239 (31%), Positives = 131/239 (54%), Gaps = 13/239 (5%)
Query: 47 LEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRA 106
++A ID+Y A E+L +RP ++ L +L A E + +
Sbjct: 218 MDAVPRIDHYRHTAAQLGEKL-LRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYT 276
Query: 107 AEAPSM---GTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAI 163
AE+ + G + GV + C+ NI+GV+LF+RL+W+VG AG+ ++L++++ T +T +
Sbjct: 277 AESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGL 336
Query: 164 SMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIA 223
S SAIATNG V GG+Y++ISRSLGPEFGGA+GL F A AMY++G E ++ +
Sbjct: 337 STSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLK 396
Query: 224 PPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISI 282
+ + +N++R+ G I + + + G+++ K + L ++++I
Sbjct: 397 EHSILMIDE---------INDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAI 446
Score = 74.3 bits (181), Expect = 6e-13
Identities = 58/242 (23%), Positives = 113/242 (46%), Gaps = 55/242 (22%)
Query: 840 IDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQM-KKDLAVFLYHLRL 898
IDVWW+ DGG+ +L+P+LL K W+ C++R+F ++ N I ++ +A L R+
Sbjct: 1024 IDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKI--NRIDHDRRAMATLLSKFRI 1081
Query: 899 E-AEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLE 957
+ +++ V+ DI+ + ++ + +++ RL + ++E++
Sbjct: 1082 DFSDIMVL----GDINTKPKKENIIAFE--EIIEPYRLHEDDKEQDI------------- 1122
Query: 958 SLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAV 1017
ADK++ +P DN EL K + +
Sbjct: 1123 -------------ADKMKED-----------EPWRITDNELELYKTK--------TYRQI 1150
Query: 1018 KLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITI 1077
+LNE++ S A ++++++P + + YM +LE L++ L +LLVRG + V+T
Sbjct: 1151 RLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTF 1210
Query: 1078 YS 1079
YS
Sbjct: 1211 YS 1212
>gi|134254459 sodium potassium chloride cotransporter 2 [Homo
sapiens]
Length = 1099
Score = 212 bits (540), Expect = 1e-54
Identities = 139/418 (33%), Positives = 203/418 (48%), Gaps = 44/418 (10%)
Query: 414 FTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEG 473
F + IFFP+ TGI+AG+N SGDL D Q +IP GT+LAI T++ Y + GAC
Sbjct: 380 FFSVFAIFFPAATGILAGANISGDLEDPQDAIPRGTMLAIFITTVAYLGVAICVGAC--- 436
Query: 474 VVLRDKYGD---------------------------------GVSRNLVVGTLAWPSPWV 500
V+RD G+ G+ N V ++ +
Sbjct: 437 -VVRDATGNMNDTIISGMNCNGSAACGLGYDFSRCRHEPCQYGLMNNFQVMSMVSGFGPL 495
Query: 501 IVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVF--GHGKVNGEPTWALLLTALI 558
I G F +T + L SL AP++ QA+ KDNI L+ F G+GK N EP +LT LI
Sbjct: 496 ITAGIFSATLSSALASLVSAPKVFQALCKDNIYKALQFFAKGYGK-NNEPLRGYILTFLI 554
Query: 559 AELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMS 618
A ILIA L+ +API+S FFL Y +N +C + ++P WRP + Y+ +S G
Sbjct: 555 AMAFILIAELNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAYGIYNMWVSLFGAV 614
Query: 619 LCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGP 678
LC A+MFV +W+ A++ +I +Y Y+ + + WG + LS +A L L
Sbjct: 615 LCCAVMFVINWWAAVITYVIEFFLYVYVTCKKPDVNWGSSTQALSYVSALDNALELTTVE 674
Query: 679 PHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQA 738
H KN+RPQ +VL + P LL GL I V G E +
Sbjct: 675 DHVKNFRPQCIVL----TGGPMTRPALLDITHAFTKNSGLCICCEVFVGPRKLCVKEMNS 730
Query: 739 AEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQS 796
+ + K+K F V A R+G+ L+Q+ GLG M+ N++V+G+ WR++
Sbjct: 731 GMAKKQAWLIKNKIKAFYAAVAADCFRDGVRSLLQASGLGRMKPNTLVIGYKKNWRKA 788
Score = 128 bits (321), Expect = 3e-29
Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 23/254 (9%)
Query: 47 LEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEH----------EEA 96
++A I+YY RN RP + + +L +T + + E+A
Sbjct: 106 MDAVPKIEYY-RNTGSISGPKVNRPSLLEIHEQLAKNVAVTPSSADRVANGDGIPGDEQA 164
Query: 97 ESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCC 156
E+ E + A G + GV + C+ NI+GV+LF+RL+W+VG AG+ +LI+L+
Sbjct: 165 ENKEDDQ---AGVVKFGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVLIILLSTM 221
Query: 157 CTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIE 216
T +T +S SAIATNG V GG+Y++ISRSLGPEFGG++GL F A AMY++G E
Sbjct: 222 VTSITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAE 281
Query: 217 ILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLA 276
++ + ++ N++R+ G+I + + + G+++ K + L
Sbjct: 282 TVVDLLKESDSMMVD---------PTNDIRIIGSITVVILLGISVAGMEWEAKAQVILLV 332
Query: 277 CVIISILSIYAGGI 290
++I+I + + G +
Sbjct: 333 ILLIAIANFFIGTV 346
Score = 79.3 bits (194), Expect = 2e-14
Identities = 66/246 (26%), Positives = 117/246 (47%), Gaps = 57/246 (23%)
Query: 837 EGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKD-LAVFLYH 895
+G IDVWW+ DGG+ +L+P++L K W+ C++RI+ ++ N I+ +K +A L
Sbjct: 908 KGTIDVWWLFDDGGLTLLIPYILTLRKKWKDCKLRIYVGGKI--NRIEEEKIVMASLLSK 965
Query: 896 LRLE-AEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSAL 954
R++ A++ ++ DI+ + + + + +M+ RL ++ ++
Sbjct: 966 FRIKFADIHII----GDINIRPNKESWKVFE--EMIEPYRLHESCKDLT----------- 1008
Query: 955 RLESLYSDEEDESAVGADKIQMTWTRDKYMTET-WDPSHAPDNFRELVHIKPDQSNVRRM 1013
T +K ET W + A EL +K +
Sbjct: 1009 ------------------------TAEKLKRETPWKITDA-----ELEAVK------EKS 1033
Query: 1014 HTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGRE 1073
+ V+LNE++ S A L++L++P + S D YM +LE+LT+ L VLLVRG +
Sbjct: 1034 YRQVRLNELLQEHSRAANLIVLSLPVARKGSISDLLYMAWLEILTKNLPPVLLVRGNHKN 1093
Query: 1074 VITIYS 1079
V+T YS
Sbjct: 1094 VLTFYS 1099
>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
Length = 714
Score = 102 bits (253), Expect = 3e-21
Identities = 57/176 (32%), Positives = 99/176 (56%), Gaps = 9/176 (5%)
Query: 413 SFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIE 472
SF + G+FFP+ TG+MAG N GDLR+ SIP+G++ A+ + +Y V L GA
Sbjct: 232 SFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIVFVFLLGAICT 291
Query: 473 GVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNI 532
LR + ++ ++ ++G + S+ + + L GAPR+LQ IA++ +
Sbjct: 292 REALR--------YDFLIAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKV 343
Query: 533 IPFLRVFGHGK-VNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVN 587
IP L G GK N P A+ LT+L+ + + ++++API+++ F++ Y+ V+
Sbjct: 344 IPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVD 399
Score = 86.7 bits (213), Expect = 1e-16
Identities = 44/104 (42%), Positives = 58/104 (55%)
Query: 113 GTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNG 172
GT GV+ C+ NIFGV+LFLR W+VG GVL + +V L+T +S +
Sbjct: 40 GTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERS 99
Query: 173 VVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIE 216
+ +GG Y MIS LG + GG +GL + G A AMYI G E
Sbjct: 100 SIGSGGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAE 143
Score = 34.3 bits (77), Expect = 0.65
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 601 WRPRFKYYH-----WALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYI 646
WR +Y W +S LG L +MFV W Y LV M +A ++Y YI
Sbjct: 582 WRRSTSFYTHMCNPW-VSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYI 631
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 50.8 bits (120), Expect = 7e-06
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 16/187 (8%)
Query: 407 VADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVL 466
+A AT F VG + TG ++R+ QK+IP+G + +++ + YF
Sbjct: 298 LAGAATCFYAFVGFDCIATTG--------EEVRNPQKAIPIGIVTSLLVCFMAYFGVSAA 349
Query: 467 FGACIEGVVLRDKYGDGVSRNLVVGTLAW-PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 525
+ +L +K V+ V W P+ +V+ GS + + L S+ PR+L
Sbjct: 350 LTLMMPYYLLDEKSPLPVAFEYV----GWGPAKYVVAAGSLCALSTSLLGSMFPLPRILF 405
Query: 526 AIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLF 585
A+A+D ++ R P A L +I+ L + L + ++S+ LM Y
Sbjct: 406 AMARDGLL--FRFLARVSKRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSL 463
Query: 586 VNLACAV 592
V AC +
Sbjct: 464 V-AACVL 469
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 47.4 bits (111), Expect = 7e-05
Identities = 46/187 (24%), Positives = 83/187 (44%), Gaps = 15/187 (8%)
Query: 407 VADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVL 466
+A AT F VG + TG ++R+ QK+IP+G + +++ + YF
Sbjct: 258 LAGAATCFYAFVGFDCIATTG--------EEVRNPQKAIPIGIVTSLLVCFMAYFGVSAA 309
Query: 467 FGACIEGVVLRDKYGDGVSRNLVVGTLAW-PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 525
+ +L +K V+ V W P+ +V+ GS + + L S+ PR++
Sbjct: 310 LTLMMPYYLLDEKSPLPVAFEYV----GWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIY 365
Query: 526 AIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLF 585
A+A+D ++ F + P A L + +A L + L + ++S+ LM Y
Sbjct: 366 AMAEDGLL-FKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSL 424
Query: 586 VNLACAV 592
V AC +
Sbjct: 425 V-AACVL 430
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 39.3 bits (90), Expect = 0.020
Identities = 42/189 (22%), Positives = 84/189 (44%), Gaps = 16/189 (8%)
Query: 406 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 465
++ AT F VG + TG A ++ Q+SIP+G ++++ L YF+
Sbjct: 253 ILRGAATCFYAFVGFDCIATTGEEA--------QNPQRSIPMGIVISLSVCFLAYFAVSS 304
Query: 466 LFGACIEGVVLRDKYGDGVSRNLVVGTLAW-PSPWVIVIGSFFSTCGAGLQSLTGAPRLL 524
+ L+ + L +G W P+ +V+ +GS + + L S+ PR++
Sbjct: 305 ALTLMMPYYQLQPE-SPLPEAFLYIG---WAPARYVVAVGSLCALSTSLLGSMFPMPRVI 360
Query: 525 QAIAKDNIIPFLRVFGHGKVNGE-PTWALLLTALIAELGILIASLDMVAPILSMFFLMCY 583
A+A+D ++ RV P A +++ +IA + L + ++S+ L+ Y
Sbjct: 361 YAMAEDGLL--FRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAY 418
Query: 584 LFVNLACAV 592
V++ +
Sbjct: 419 SLVSICVLI 427
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 39.3 bits (90), Expect = 0.020
Identities = 42/189 (22%), Positives = 84/189 (44%), Gaps = 16/189 (8%)
Query: 406 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 465
++ AT F VG + TG A ++ Q+SIP+G ++++ L YF+
Sbjct: 253 ILRGAATCFYAFVGFDCIATTGEEA--------QNPQRSIPMGIVISLSVCFLAYFAVSS 304
Query: 466 LFGACIEGVVLRDKYGDGVSRNLVVGTLAW-PSPWVIVIGSFFSTCGAGLQSLTGAPRLL 524
+ L+ + L +G W P+ +V+ +GS + + L S+ PR++
Sbjct: 305 ALTLMMPYYQLQPE-SPLPEAFLYIG---WAPARYVVAVGSLCALSTSLLGSMFPMPRVI 360
Query: 525 QAIAKDNIIPFLRVFGHGKVNGE-PTWALLLTALIAELGILIASLDMVAPILSMFFLMCY 583
A+A+D ++ RV P A +++ +IA + L + ++S+ L+ Y
Sbjct: 361 YAMAEDGLL--FRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAY 418
Query: 584 LFVNLACAV 592
V++ +
Sbjct: 419 SLVSICVLI 427
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 38.1 bits (87), Expect = 0.045
Identities = 44/209 (21%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Query: 406 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFS--- 462
V++ AT F VG + TG ++++ QK+IPVG + +++ + YF
Sbjct: 255 VLSGAATCFYAFVGFDCIATTG--------EEVKNPQKAIPVGIVASLLICFIAYFGVSA 306
Query: 463 --SVVLFGACIE-GVVLRDKYGDGVSRNLVVGTLAWP-SPWVIVIGSFFSTCGAGLQSLT 518
++++ C++ L D + + W + + + +GS + + L S+
Sbjct: 307 ALTLMMPYFCLDNNSPLPDAFKH----------VGWEGAKYAVAVGSLCALSASLLGSMF 356
Query: 519 GAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMF 578
PR++ A+A+D ++ F + P A L + +A + + L + ++S+
Sbjct: 357 PMPRVIYAMAEDGLL-FKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIG 415
Query: 579 FLMCYLFVNLACAVQTLLRTPNWRPRFKY 607
L+ Y +L A +LR +P Y
Sbjct: 416 TLLAY---SLVAACVLVLRYQPEQPNLVY 441
>gi|10947061 adenylate cyclase 6 isoform b [Homo sapiens]
Length = 1115
Score = 37.4 bits (85), Expect = 0.077
Identities = 58/248 (23%), Positives = 101/248 (40%), Gaps = 37/248 (14%)
Query: 52 GIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPS 111
GID ++ ++ L+ +V L + + ++ Q K+H R + S
Sbjct: 603 GIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS 662
Query: 112 --MGTLMGVYLPCLQNIFGVILFLRL------TWMVGT-AGVLQALLIVLICC----CCT 158
+ G Y+ C +F I F++L T M+G A + LLI ++ C C +
Sbjct: 663 RKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSCGS 722
Query: 159 L----LTAISMSAIATNGVVPAGGSYFMI----SRSLGPEFGGAVGLCFYLGTTFA---- 206
L L +S S + + A G + ++ S F G + L + F
Sbjct: 723 LFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMYFIGNMLLSLLASSVFLHISS 782
Query: 207 ----AAMYILGAIEILLTYIAPPAAIF----YPSGAHD--TSNATLNNM--RVYGTIFLT 254
A +++LG I ++L + PPA IF G H +SN T + + G + L
Sbjct: 783 IGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALK 842
Query: 255 FMTLVVFV 262
+MT V+ +
Sbjct: 843 YMTPVILL 850
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 36.2 bits (82), Expect = 0.17
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 406 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 465
V+ AT F +G + TG A ++ SIP +++ Y S V
Sbjct: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
Query: 466 LFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 525
+ + + + + V + + +V+ IGS + L SL PR++
Sbjct: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
Query: 526 AIAKDNIIPFLRVFGH-GKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYL 584
A+A D ++ R H P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
Query: 585 FVNL 588
V++
Sbjct: 421 LVSV 424
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 35.4 bits (80), Expect = 0.29
Identities = 39/188 (20%), Positives = 83/188 (44%), Gaps = 26/188 (13%)
Query: 869 RMRIFTVAQMDDNSIQ----MKKDLAVFLYHLRLEAEVEV---VEMHNSDISAYTYERTL 921
R RI + + S+Q KDLAV L + + E+ VE H +++ + +++
Sbjct: 566 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 625
Query: 922 MMEQRSQMLRQMRLTKTERERE------AQLVKDRHSALR----------LESLYSDEED 965
+ ++ Q+L+Q T+ E+ RE L+KD+ + LE L + +
Sbjct: 626 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTE 685
Query: 966 ESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQS---NVRRMHTAVKLNEV 1022
++ ++ ++ R K E D ++ + K D+ + +++ + +K +EV
Sbjct: 686 LESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEV 745
Query: 1023 IVTRSHDA 1030
+ R+ A
Sbjct: 746 SIQRTEKA 753
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 34.7 bits (78), Expect = 0.50
Identities = 24/123 (19%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
Query: 858 LLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTY 917
++ H + + +MR+ + ++ +KD A L +++A + + +I +T
Sbjct: 428 IVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEML-GAKIKAMESKLLVGGKNIVDHTN 486
Query: 918 ERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMT 977
E+ ++EQ+ Q + + + + ERE + Q+ L L+ YS + E + K++
Sbjct: 487 EQQKILEQKRQEIAEQK--RREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKL 544
Query: 978 WTR 980
+++
Sbjct: 545 FSK 547
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,258,225
Number of Sequences: 37866
Number of extensions: 1710218
Number of successful extensions: 4378
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 4280
Number of HSP's gapped (non-prelim): 85
length of query: 1079
length of database: 18,247,518
effective HSP length: 113
effective length of query: 966
effective length of database: 13,968,660
effective search space: 13493725560
effective search space used: 13493725560
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.