Guide to the Human Genome
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Search of human proteins with 224922839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224922839 hypothetical protein LOC138311 [Homo sapiens]
         (431 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224922839 hypothetical protein LOC138311 [Homo sapiens]            888   0.0  
gi|165932391 family with sequence similarity 69, member A [Homo ...   434   e-122
gi|195546915 hypothetical protein LOC125704 [Homo sapiens]             88   1e-17
gi|14149946 protein kinase-like protein SgK196 [Homo sapiens]          34   0.22 
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]                32   1.1  
gi|169169677 PREDICTED: hypothetical protein [Homo sapiens]            30   3.2  
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]         30   3.2  
gi|22779873 family with sequence similarity 89, member B isoform...    30   4.2  
gi|4758844 nucleoporin 155kDa isoform 2 [Homo sapiens]                 30   4.2  
gi|24430149 nucleoporin 155kDa isoform 1 [Homo sapiens]                30   4.2  
gi|116284392 mucin 2 precursor [Homo sapiens]                          29   9.4  
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              29   9.4  
gi|30425428 deltex homolog 3 [Homo sapiens]                            29   9.4  
gi|5901884 cytochrome b-561 domain containing 2 [Homo sapiens]         29   9.4  

>gi|224922839 hypothetical protein LOC138311 [Homo sapiens]
          Length = 431

 Score =  888 bits (2294), Expect = 0.0
 Identities = 431/431 (100%), Positives = 431/431 (100%)

Query: 1   MRRLRRLAHLVLFCPFSKRLQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGH 60
           MRRLRRLAHLVLFCPFSKRLQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGH
Sbjct: 1   MRRLRRLAHLVLFCPFSKRLQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGH 60

Query: 61  VCQVVICDQYRKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIE 120
           VCQVVICDQYRKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIE
Sbjct: 61  VCQVVICDQYRKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIE 120

Query: 121 ETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLM 180
           ETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLM
Sbjct: 121 ETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLM 180

Query: 181 ADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWH 240
           ADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWH
Sbjct: 181 ADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWH 240

Query: 241 AAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTL 300
           AAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTL
Sbjct: 241 AAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTL 300

Query: 301 ANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGD 360
           ANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGD
Sbjct: 301 ANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGD 360

Query: 361 LIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTL 420
           LIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTL
Sbjct: 361 LIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTL 420

Query: 421 LWKKISNTKYS 431
           LWKKISNTKYS
Sbjct: 421 LWKKISNTKYS 431


>gi|165932391 family with sequence similarity 69, member A [Homo
           sapiens]
          Length = 428

 Score =  434 bits (1117), Expect = e-122
 Identities = 199/412 (48%), Positives = 281/412 (68%)

Query: 20  LQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQYRKGIISGSV 79
           LQ R   +R++ +F +WL VF GSW++YV YS+Y+E CRG  C+ +ICD+Y+ G+I G  
Sbjct: 17  LQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPA 76

Query: 80  CQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVL 139
           C  LC    + +  CLS  P  Q+Y G+W +    +KC +E+ L     ++  PR+E+VL
Sbjct: 77  CNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVL 136

Query: 140 FDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDNRVSLAEAKSVWA 199
           FDKPTRGT++++F+EM  S  KA LGD  +L  LV  +L +AD +KD +VSL EAKS WA
Sbjct: 137 FDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWA 196

Query: 200 LLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGA 259
           LLQ NEFLL++ LQ+KEH  +L+G+CGDLY+ E V + + +  +LP ++   +P   + +
Sbjct: 197 LLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRS 256

Query: 260 LQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQV 319
           + Q   P+WP +AKIAIGLLEFVE++FHG YG F MC+T+  N+GY   YD KM D++++
Sbjct: 257 MDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKI 316

Query: 320 APEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPNLAKVCALLRGYLLP 379
            PE  ++  ++ R CE   DC YG DCR  CD+   +C  ++IQPNLAK C LL+ YLL 
Sbjct: 317 VPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLR 376

Query: 380 GAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKKISNTKYS 431
           GAP+++REEL  QL +C  L   A+Q+E  HSL+L++LKTLLWKKIS T  S
Sbjct: 377 GAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS 428


>gi|195546915 hypothetical protein LOC125704 [Homo sapiens]
          Length = 419

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 88/346 (25%), Positives = 143/346 (41%), Gaps = 31/346 (8%)

Query: 33  FLAWLG--VFAGSWLVYVHYSSYSERCRGHVCQVVI---CDQYRKGIISGSVCQDLCELH 87
           F AW    V A + L+  H    SERC     + ++   C  Y+ G ++G +C+DLC   
Sbjct: 28  FAAWTAGWVLAAALLLRAHPGVLSERCTDEKSRRILAALCQDYQGGTLAGDLCEDLCVAG 87

Query: 88  MVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGT 147
            + ++ CL    G++V    WR + V +K   E      A S   P   L L ++   G 
Sbjct: 88  ELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEE------AFSSFPP---LSLLEEEA-GE 137

Query: 148 SIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDNRVSL--AEAKSVWALLQRNE 205
             ++  E  L  + A  G++ S   L      +  +    R      +  S+WALLQ+ E
Sbjct: 138 GGQDMPEAELLLMVA--GEVKSALGLELSNSSLGPWWPGRRGPRWRGQLASLWALLQQEE 195

Query: 206 FLLLLSLQE-KEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGALQQWL 264
           ++    LQ+   H   +LG CG  Y  E +  G+ H  AL PL R   P A  G   + +
Sbjct: 196 YVYFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDR--APGAPGGGQAKAI 253

Query: 265 GPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEAT 324
                  + IA+  L+ V           ++C+    N    + +     D+     E  
Sbjct: 254 -------SDIALSFLDMVNHFDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDMAFFEPK 306

Query: 325 VRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPNLAKVC 370
           +R  L+ + C    DC +  DC + CD  + +C    +  NL  +C
Sbjct: 307 MREILE-QNCTGDEDCNF-FDCFSRCDLRVNKCGAQRVNNNLQVIC 350


>gi|14149946 protein kinase-like protein SgK196 [Homo sapiens]
          Length = 350

 Score = 34.3 bits (77), Expect = 0.22
 Identities = 41/143 (28%), Positives = 62/143 (43%), Gaps = 26/143 (18%)

Query: 185 KDNRVSLAEAKSVWALLQRNEFL----LLLSLQEKEHASRLLGYCGD--LYLTEGVPHGA 238
           K+++V+L++  S   L  +++FL    +L SLQ   H   LLGYC D    LTE  P G+
Sbjct: 101 KEHKVALSQLTS---LEMKDDFLHGLQMLKSLQGT-HVVTLLGYCEDDNTMLTEYHPLGS 156

Query: 239 WHAAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCET 298
                L  L   L     Q          W  R ++A+  +  +  L H   GT  MC++
Sbjct: 157 -----LSNLEETLNLSKYQNV------NTWQHRLELAMDYVSIINYLHHSPVGTRVMCDS 205

Query: 299 -----TLANVGYTATYDFKMADL 316
                TL+    T+ +     DL
Sbjct: 206 NDLPKTLSQYLLTSNFSILANDL 228


>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
          Length = 1140

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 13/113 (11%)

Query: 314 ADLQQVAPEATVRRFLQGRRCEHSTDC-TYGRDCRAPCDRLMRQCKGDLIQPNLAKVCAL 372
           AD   ++ + T R    GR CE      TYG  CR  CD     C  +    ++   C  
Sbjct: 765 ADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD-----CLNNSTCDHITGTCYC 819

Query: 373 LRGYLLPGAPAD-----LREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTL 420
             G+   GA  D     +   L +  RT T L   + Q+ A   +++  L  L
Sbjct: 820 SPGW--KGARCDQAGVIIVGNLNSLSRTSTALPADSYQIGAIAGIIILVLVVL 870


>gi|169169677 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 167

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 14/26 (53%), Positives = 16/26 (61%)

Query: 242 AALPPLLRPLLPPALQGALQQWLGPA 267
           A  PP   PLLPPA  G  ++WLG A
Sbjct: 42  APRPPASDPLLPPAFPGWGERWLGRA 67


>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
          Length = 544

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 128 RSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLK-ANLGDLPSLPA-----LVGQVLLMA 181
           R ++AP  +  L     R    KE   +TLS +K +  G  PSL +     +  Q L+  
Sbjct: 412 RQNSAPLLQTALLGNGERPPGAKEAPPLTLSLVKPSGRGAAPSLTSQAAAQVANQALIRG 471

Query: 182 DFNKDNRVSLAEAKSV 197
           D+N+   V +A  + V
Sbjct: 472 DWNRGGGVRVASVQQV 487


>gi|22779873 family with sequence similarity 89, member B isoform 2
           [Homo sapiens]
          Length = 176

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 19/96 (19%)

Query: 184 NKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDL----YLTEGVPHGAW 239
           N D+ ++    + +W L +        S+Q+ +H  + L +C DL    +     P  A 
Sbjct: 85  NLDSALAALRKEMLWGLYE--------SIQDYKHLCQDLSFCQDLSSSLHSDSSYPPDAG 136

Query: 240 HA-------AALPPLLRPLLPPALQGALQQWLGPAW 268
            +       A+LPP   PL  P    A  QWL  A+
Sbjct: 137 LSDDEEPPDASLPPDPPPLTVPQTHNARDQWLQDAF 172


>gi|4758844 nucleoporin 155kDa isoform 2 [Homo sapiens]
          Length = 1332

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 21/114 (18%)

Query: 118 GIEETLDSKARSDAAP----------RRELVLFDKPTRGTSIKEFREMTLSFLKANLGDL 167
           G++E LD  ++    P          ++ L+ F +P  G   +  +E+   F +A L + 
Sbjct: 657 GLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEK 716

Query: 168 PSLPALVGQVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRL 221
            SL A+  Q L+   +         +A ++W LL  ++F ++++  +KE   +L
Sbjct: 717 ISLQAI--QQLVRKSY---------QALALWKLLCEHQFTIIVAELQKELQEQL 759


>gi|24430149 nucleoporin 155kDa isoform 1 [Homo sapiens]
          Length = 1391

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 21/114 (18%)

Query: 118 GIEETLDSKARSDAAP----------RRELVLFDKPTRGTSIKEFREMTLSFLKANLGDL 167
           G++E LD  ++    P          ++ L+ F +P  G   +  +E+   F +A L + 
Sbjct: 716 GLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEK 775

Query: 168 PSLPALVGQVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRL 221
            SL A+  Q L+   +         +A ++W LL  ++F ++++  +KE   +L
Sbjct: 776 ISLQAI--QQLVRKSY---------QALALWKLLCEHQFTIIVAELQKELQEQL 818


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 28.9 bits (63), Expect = 9.4
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 14/68 (20%)

Query: 98   APGQQVYSGLWRDKDVTIKCGIEETLD--------------SKARSDAAPRRELVLFDKP 143
            APG++VY+G + D    + C +  TL+              + ++S   P +      KP
Sbjct: 4344 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKP 4403

Query: 144  TRGTSIKE 151
            T GT   E
Sbjct: 4404 TPGTKPPE 4411


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 28.9 bits (63), Expect = 9.4
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 14/68 (20%)

Query: 98   APGQQVYSGLWRDKDVTIKCGIEETLD--------------SKARSDAAPRRELVLFDKP 143
            APG++VY+G + D    + C +  TL+              + ++S   P +      KP
Sbjct: 1804 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKP 1863

Query: 144  TRGTSIKE 151
            T GT   E
Sbjct: 1864 TPGTKPPE 1871


>gi|30425428 deltex homolog 3 [Homo sapiens]
          Length = 347

 Score = 28.9 bits (63), Expect = 9.4
 Identities = 25/61 (40%), Positives = 26/61 (42%), Gaps = 3/61 (4%)

Query: 201 LQRNEFLLLLSLQEKE--HASRLLGYCGDLYLTEGVPHGAWHAAALPPL-LRPLLPPALQ 257
           L R     LL   EKE   A R     G L L  G  H   H A  PPL   PLLPP  +
Sbjct: 77  LARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLLPPGAR 136

Query: 258 G 258
           G
Sbjct: 137 G 137


>gi|5901884 cytochrome b-561 domain containing 2 [Homo sapiens]
          Length = 222

 Score = 28.9 bits (63), Expect = 9.4
 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 218 ASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLL 252
           AS LLG C  L+ T  V   AW+ A L P+L  L+
Sbjct: 172 ASLLLGMCS-LWFTASVTGAAWYLAVLCPVLTSLV 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,309,483
Number of Sequences: 37866
Number of extensions: 773290
Number of successful extensions: 2398
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2382
Number of HSP's gapped (non-prelim): 21
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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