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Search of human proteins with 224922791
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo
sapiens]
(594 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo ... 1227 0.0
gi|21361513 amidohydrolase domain containing 2 isoform 1 [Homo s... 868 0.0
gi|228008407 serine active site containing 1 [Homo sapiens] 32 1.3
gi|93204865 hypothetical protein LOC57724 [Homo sapiens] 32 1.3
gi|73695936 ADAM metallopeptidase with thrombospondin type 1 mot... 31 2.8
gi|21265034 ADAM metallopeptidase with thrombospondin type 1 mot... 31 2.8
gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo... 31 2.8
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 30 6.3
gi|22749325 zinc finger protein 48 [Homo sapiens] 30 6.3
gi|4507267 stanniocalcin 2 precursor [Homo sapiens] 30 8.2
gi|28872803 myeloid translocation gene on chromosome 16 isoform ... 30 8.2
gi|28872805 myeloid translocation gene on chromosome 16 isoform ... 30 8.2
gi|106049528 pyruvate carboxylase precursor [Homo sapiens] 30 8.2
gi|106049295 pyruvate carboxylase precursor [Homo sapiens] 30 8.2
gi|106049292 pyruvate carboxylase precursor [Homo sapiens] 30 8.2
>gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo
sapiens]
Length = 594
Score = 1227 bits (3175), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 1 MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGG 60
MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGG
Sbjct: 1 MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGG 60
Query: 61 RILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHK 120
RILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHK
Sbjct: 61 RILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHK 120
Query: 121 VVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDN 180
VVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDN
Sbjct: 121 VVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDN 180
Query: 181 VRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPF 240
VRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPF
Sbjct: 181 VRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPF 240
Query: 241 HHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALG 300
HHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALG
Sbjct: 241 HHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALG 300
Query: 301 LGNGRHTLGQQEVEVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSG 360
LGNGRHTLGQQEVEVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSG
Sbjct: 301 LGNGRHTLGQQEVEVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSG 360
Query: 361 SIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLH 420
SIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLH
Sbjct: 361 SIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLH 420
Query: 421 VQATYISGPVLAGCGDPAWCWRAVWEAPVCPAHPISVILPSSVSPWPWHTPMWQTRAVRL 480
VQATYISGPVLAGCGDPAWCWRAVWEAPVCPAHPISVILPSSVSPWPWHTPMWQTRAVRL
Sbjct: 421 VQATYISGPVLAGCGDPAWCWRAVWEAPVCPAHPISVILPSSVSPWPWHTPMWQTRAVRL 480
Query: 481 PEQLRGGWASGALLALRTATVGSDVRDWCSPTSGVIVLTFSPFEFWGGWLPSPLLTGAVL 540
PEQLRGGWASGALLALRTATVGSDVRDWCSPTSGVIVLTFSPFEFWGGWLPSPLLTGAVL
Sbjct: 481 PEQLRGGWASGALLALRTATVGSDVRDWCSPTSGVIVLTFSPFEFWGGWLPSPLLTGAVL 540
Query: 541 GTGGTRLALPLFSSLCCKAQLRKCLQVQRDRMVWAPPVGREQPGKNHLPGQGLA 594
GTGGTRLALPLFSSLCCKAQLRKCLQVQRDRMVWAPPVGREQPGKNHLPGQGLA
Sbjct: 541 GTGGTRLALPLFSSLCCKAQLRKCLQVQRDRMVWAPPVGREQPGKNHLPGQGLA 594
>gi|21361513 amidohydrolase domain containing 2 isoform 1 [Homo
sapiens]
Length = 439
Score = 868 bits (2243), Expect = 0.0
Identities = 428/431 (99%), Positives = 430/431 (99%)
Query: 1 MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGG 60
MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGG
Sbjct: 1 MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGG 60
Query: 61 RILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHK 120
RILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHK
Sbjct: 61 RILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHK 120
Query: 121 VVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDN 180
VVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDN
Sbjct: 121 VVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDN 180
Query: 181 VRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPF 240
VRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPF
Sbjct: 181 VRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPF 240
Query: 241 HHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALG 300
HHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALG
Sbjct: 241 HHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALG 300
Query: 301 LGNGRHTLGQQEVEVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSG 360
LGNGRHTLGQQEVEVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSG
Sbjct: 301 LGNGRHTLGQQEVEVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSG 360
Query: 361 SIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLH 420
SIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLH
Sbjct: 361 SIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLH 420
Query: 421 VQATYISGPVL 431
VQATYISG ++
Sbjct: 421 VQATYISGELV 431
>gi|228008407 serine active site containing 1 [Homo sapiens]
Length = 654
Score = 32.3 bits (72), Expect = 1.3
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 440 CWRAVWEAPVCPA-HPISVILPSSVSPWPWHTPM-WQTRAVRLPEQLRGGWASGALLALR 497
CW W A CPA ISV +S+S W PM ++ A R E LR LR
Sbjct: 433 CWPKTWLAKDCPALRIISVEYDTSLSDWRARCPMERKSIAFRSNELLR---------KLR 483
Query: 498 TATVGSDVRDWCSPTSGVIVL 518
A VG W S + G +++
Sbjct: 484 AAGVGDRPVVWISHSMGGLLV 504
>gi|93204865 hypothetical protein LOC57724 [Homo sapiens]
Length = 2579
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 12/73 (16%)
Query: 448 PVCPAHPISVILPSSVSPWPWHTPMWQTRAVRLPEQLRGGWASGALLALRTATVGSDVRD 507
P CPA P SV +P +H L + ++ G G LAL VG +
Sbjct: 986 PNCPAVPFSVTVPDMTESPTFHP---------LLKAVKAGMPIGCYLALSMTAVGHSIEK 1036
Query: 508 WCS---PTSGVIV 517
+C+ P G++V
Sbjct: 1037 FCAEGIPLLGILV 1049
>gi|73695936 ADAM metallopeptidase with thrombospondin type 1 motif,
13 isoform 2 preproprotein [Homo sapiens]
Length = 1371
Score = 31.2 bits (69), Expect = 2.8
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
Query: 536 TGAVLGTGGTRLALPLFSSLCCKAQLRKCLQVQRDRMVWAPPVGREQPG 584
+G V+ + G L S C + QL L R R VW PP R QPG
Sbjct: 245 SGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPP--RPQPG 291
>gi|21265034 ADAM metallopeptidase with thrombospondin type 1 motif,
13 isoform 1 preproprotein [Homo sapiens]
Length = 1427
Score = 31.2 bits (69), Expect = 2.8
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
Query: 536 TGAVLGTGGTRLALPLFSSLCCKAQLRKCLQVQRDRMVWAPPVGREQPG 584
+G V+ + G L S C + QL L R R VW PP R QPG
Sbjct: 245 SGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPP--RPQPG 291
>gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo
sapiens]
Length = 654
Score = 31.2 bits (69), Expect = 2.8
Identities = 17/49 (34%), Positives = 25/49 (51%)
Query: 356 KTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTL 404
+TL IA +D + F + GC E +EA LH + ++ SKG L
Sbjct: 490 ETLENIIATVDTRLPEFSELQGCFREELMEALHLHLVKEYIIQLSKGRL 538
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 30.0 bits (66), Expect = 6.3
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 5/70 (7%)
Query: 330 LGPRSQPACQVAHDPPR-ACPLCSQGTKTLSGSIAPMDVCVRHFLQ----ATGCSMESAL 384
L P Q CQ ++ AC CS G S +P C H L AT C E
Sbjct: 254 LVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGF 313
Query: 385 EAASLHPAQL 394
A PA +
Sbjct: 314 FRAPQDPASM 323
>gi|22749325 zinc finger protein 48 [Homo sapiens]
Length = 618
Score = 30.0 bits (66), Expect = 6.3
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 324 GERPDPLGPRS-QPACQVAHDPPRACPLCSQGTKTLS 359
G P+P GP++ +P +A D P CP C +G + S
Sbjct: 428 GLEPEPGGPQAGEPPPPLAGDKPHKCPECGKGFRRSS 464
>gi|4507267 stanniocalcin 2 precursor [Homo sapiens]
Length = 302
Score = 29.6 bits (65), Expect = 8.2
Identities = 20/67 (29%), Positives = 25/67 (37%), Gaps = 8/67 (11%)
Query: 103 VTSFCPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGA-------- 154
+ SFC + + PP + PQ+ G G HL P RGA
Sbjct: 207 ILSFCTSAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKS 266
Query: 155 HPEAHLR 161
HP AH R
Sbjct: 267 HPNAHAR 273
>gi|28872803 myeloid translocation gene on chromosome 16 isoform
MTG16a [Homo sapiens]
Length = 653
Score = 29.6 bits (65), Expect = 8.2
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 102 GVTSFCPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLG 139
G T+ V PPE H + P +PV + P AG G
Sbjct: 598 GPTAVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAG 635
>gi|28872805 myeloid translocation gene on chromosome 16 isoform
MTG16b [Homo sapiens]
Length = 567
Score = 29.6 bits (65), Expect = 8.2
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 102 GVTSFCPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLG 139
G T+ V PPE H + P +PV + P AG G
Sbjct: 512 GPTAVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAG 549
>gi|106049528 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 29.6 bits (65), Expect = 8.2
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 11/92 (11%)
Query: 115 PEVYH-KVVPQIPVKSGGPHGAGVLGLHL---EGPFISREKRGAHPEAHLRS-FEADAF- 168
PE + KV+ +P G P GA + L L E + R PE L + D F
Sbjct: 960 PEPFRSKVLKDLPRVEGRP-GASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFA 1018
Query: 169 --QDLLATYGPLD--NVRIVTLAPELGRSHEV 196
+D AT+GPLD N R+ P++ EV
Sbjct: 1019 HFKDFTATFGPLDSLNTRLFLQGPKIAEEFEV 1050
>gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 29.6 bits (65), Expect = 8.2
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 11/92 (11%)
Query: 115 PEVYH-KVVPQIPVKSGGPHGAGVLGLHL---EGPFISREKRGAHPEAHLRS-FEADAF- 168
PE + KV+ +P G P GA + L L E + R PE L + D F
Sbjct: 960 PEPFRSKVLKDLPRVEGRP-GASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFA 1018
Query: 169 --QDLLATYGPLD--NVRIVTLAPELGRSHEV 196
+D AT+GPLD N R+ P++ EV
Sbjct: 1019 HFKDFTATFGPLDSLNTRLFLQGPKIAEEFEV 1050
>gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 29.6 bits (65), Expect = 8.2
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 11/92 (11%)
Query: 115 PEVYH-KVVPQIPVKSGGPHGAGVLGLHL---EGPFISREKRGAHPEAHLRS-FEADAF- 168
PE + KV+ +P G P GA + L L E + R PE L + D F
Sbjct: 960 PEPFRSKVLKDLPRVEGRP-GASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFA 1018
Query: 169 --QDLLATYGPLD--NVRIVTLAPELGRSHEV 196
+D AT+GPLD N R+ P++ EV
Sbjct: 1019 HFKDFTATFGPLDSLNTRLFLQGPKIAEEFEV 1050
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,218,815
Number of Sequences: 37866
Number of extensions: 1324211
Number of successful extensions: 2796
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2790
Number of HSP's gapped (non-prelim): 15
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.