Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 224831241

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
         (2036 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         3918   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         3831   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         3810   0.0  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  2588   0.0  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   2519   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  2446   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  2441   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  2440   0.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  2435   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  1306   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  1295   0.0  
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1293   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1293   0.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  1291   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  1288   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  1288   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     1285   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  1276   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  1245   0.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             1141   0.0  
gi|122937345 myosin VB [Homo sapiens]                                 554   e-157
gi|153945715 myosin VC [Homo sapiens]                                 549   e-156
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       536   e-152
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       534   e-151
gi|28416946 myosin 18A isoform a [Homo sapiens]                       531   e-150
gi|42794779 myosin 18A isoform b [Homo sapiens]                       526   e-149
gi|154354979 myosin X [Homo sapiens]                                  464   e-130
gi|122937512 myosin VIIB [Homo sapiens]                               449   e-125
gi|118402590 myosin XV [Homo sapiens]                                 449   e-125
gi|194328685 myosin IB isoform 1 [Homo sapiens]                       441   e-123

>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 3918 bits (10161), Expect = 0.0
 Identities = 2036/2036 (100%), Positives = 2036/2036 (100%)

Query: 1    MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
            MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1    MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60

Query: 61   ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
            ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61   ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120

Query: 121  VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
            VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121  VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180

Query: 181  AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
            AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
Sbjct: 181  AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240

Query: 241  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
            ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 241  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300

Query: 301  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
            RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 301  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360

Query: 361  RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
            RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 361  RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420

Query: 421  RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
            RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 421  RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480

Query: 481  FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
            FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 481  FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540

Query: 541  DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
            DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 541  DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600

Query: 601  DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
            DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
Sbjct: 601  DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660

Query: 661  SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
            SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 661  SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720

Query: 721  RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
            RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 721  RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780

Query: 781  EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
            EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 781  EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840

Query: 841  DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
            DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 841  DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900

Query: 901  PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
            PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 901  PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960

Query: 961  CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
            CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 961  CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020

Query: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
            EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080

Query: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
            KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140

Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
            AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200

Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
            DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260

Query: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
            QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320

Query: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
            EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380

Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
            LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440

Query: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
            EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500

Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
            VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560

Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
            ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620

Query: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
            LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680

Query: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
            EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740

Query: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
            KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800

Query: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
            EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860

Query: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
            EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920

Query: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
            RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980

Query: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
            TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 3831 bits (9935), Expect = 0.0
 Identities = 2003/2036 (98%), Positives = 2003/2036 (98%), Gaps = 33/2036 (1%)

Query: 1    MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
            MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1    MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60

Query: 61   ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
            ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61   ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120

Query: 121  VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
            VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121  VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180

Query: 181  AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
            AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
Sbjct: 181  AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240

Query: 241  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
            ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 241  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300

Query: 301  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
            RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 301  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360

Query: 361  RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
            RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 361  RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420

Query: 421  RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
            RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 421  RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480

Query: 481  FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
            FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 481  FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540

Query: 541  DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
            DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 541  DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600

Query: 601  DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
            DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD            
Sbjct: 601  DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------ 648

Query: 661  SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
                                 VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 649  ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 687

Query: 721  RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
            RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 688  RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 747

Query: 781  EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
            EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 748  EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 807

Query: 841  DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
            DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 808  DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 867

Query: 901  PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
            PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 868  PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 927

Query: 961  CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
            CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 928  CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 987

Query: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
            EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 988  EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1047

Query: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
            KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1048 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1107

Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
            AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1108 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1167

Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
            DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1168 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1227

Query: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
            QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1228 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1287

Query: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
            EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1288 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1347

Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
            LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1348 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1407

Query: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
            EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1408 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1467

Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
            VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527

Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
            ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1587

Query: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
            LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1588 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1647

Query: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
            EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1648 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1707

Query: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
            KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1708 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1767

Query: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
            EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1768 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1827

Query: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
            EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1828 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1887

Query: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
            RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1888 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1947

Query: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
            TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1948 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2003


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 3810 bits (9880), Expect = 0.0
 Identities = 1995/2036 (97%), Positives = 1995/2036 (97%), Gaps = 41/2036 (2%)

Query: 1    MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
            MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1    MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60

Query: 61   ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
            ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61   ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120

Query: 121  VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
            VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121  VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180

Query: 181  AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
            AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP        G
Sbjct: 181  AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G 232

Query: 241  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
            ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 233  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292

Query: 301  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
            RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 293  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 352

Query: 361  RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
            RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 353  RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412

Query: 421  RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
            RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 413  RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 472

Query: 481  FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
            FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 473  FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 532

Query: 541  DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
            DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 533  DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 592

Query: 601  DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
            DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD            
Sbjct: 593  DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------ 640

Query: 661  SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
                                 VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 641  ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 679

Query: 721  RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
            RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 680  RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 739

Query: 781  EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
            EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 740  EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 799

Query: 841  DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
            DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 800  DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 859

Query: 901  PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
            PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 860  PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 919

Query: 961  CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
            CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 920  CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 979

Query: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
            EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 980  EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1039

Query: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
            KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1040 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1099

Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
            AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1100 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1159

Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
            DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1160 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1219

Query: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
            QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1220 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1279

Query: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
            EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1280 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1339

Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
            LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1340 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1399

Query: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
            EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1400 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1459

Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
            VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519

Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
            ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1579

Query: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
            LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1580 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1639

Query: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
            EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1640 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1699

Query: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
            KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1700 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1759

Query: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
            EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1760 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1819

Query: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
            EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1820 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1879

Query: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
            RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1880 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1939

Query: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
            TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1940 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 1995


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 2588 bits (6707), Expect = 0.0
 Identities = 1312/1989 (65%), Positives = 1622/1989 (81%), Gaps = 48/1989 (2%)

Query: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
            Q +WTA++LVW+PSE HGFEAA++++E  +E  VELAE+G++  + +D IQ+MNPPKFSK
Sbjct: 27   QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86

Query: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
             EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK
Sbjct: 87   VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146

Query: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
            RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK
Sbjct: 147  RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206

Query: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            +  +P        GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207  DHNIP--------GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
            ANIETYLLEKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE  ++YRFL+NG    P
Sbjct: 259  ANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIP 318

Query: 347  GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
            GQ+ ++ FQET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT A
Sbjct: 319  GQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVA 378

Query: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
            QKLC LLG+ V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV 
Sbjct: 379  QKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVH 438

Query: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
            R+N+ALDR+ RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439  RINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498

Query: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
            YQREGI W F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG
Sbjct: 499  YQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQG 558

Query: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
             H KFQ+PR L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR  AE+
Sbjct: 559  SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGG--RP 703
            WKD                                 V+ IVGL+QV+ + +   G   + 
Sbjct: 619  WKD---------------------------------VDRIVGLDQVTGMTETAFGSAYKT 645

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            ++GMFRTVGQLYKESL++LMATL NTNP+FVRCI+PNHEKRAGKL+P LVLDQLRCNGVL
Sbjct: 646  KKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVL 705

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
            EGIRICRQGFPNRI+FQEFRQRYEILTPNAIPKGFMDGKQACE+MI+ALELDPNLYR+GQ
Sbjct: 706  EGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765

Query: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
            SKIFFRAGVLA LEEERDLK+TDII+ FQA  RGYLAR+AF K+QQQ SAL+V+QRNCAA
Sbjct: 766  SKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAA 825

Query: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
            YLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+ +EL KV+E Q +   E+ E++ +  QL
Sbjct: 826  YLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQL 885

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
             EE+  LAEQL+AE EL AEAEE R RLAA+KQELE ++ +LE+RV EEEE ++ +Q EK
Sbjct: 886  LEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEK 945

Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
            K++Q HIQ+LE  L+ EEGARQKLQLEKVT EAK+KK EE++LLLEDQNSK  KE+KL+E
Sbjct: 946  KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005

Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
            DR+AE SSQ AEEEEK K+L K+R K E  I+D+E+RL+KEEK RQELEK KR+LDGE++
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT 1065

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
            +LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR +DE   +   LK +RE QA +AE QE
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125

Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
            D ESE+ +R KAEKQ+RDL EELEAL+ ELEDTLD+T AQQELR+KREQEV ELKK LEE
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            ET+ HEA +Q++RQRH  AL EL+EQLEQA+R K   EK +  LE +  EL  E+  LQ 
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
             + E E +R++L+ Q+QE+  +  +G+R R E AEK  + Q EL+NVS  L EAE K I+
Sbjct: 1246 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1305

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
             +K+ +S E+QL D QELLQEETR KL L SR+R +E E   L+EQ EEE  AR+   ++
Sbjct: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365

Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
            +   Q+QL++ +++ +++ G +E+ EEA+++  ++AEAL+QRL EK    D+LE+ + RL
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            QQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLAEEK+   R  EER+RAEAE RE+E +A
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
            LSL RALEE  EA+EE ERQN+ LRA++E L+SSKDDVGK+VHELE++ R  EQ   ++R
Sbjct: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
             Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQ RDE  EE++R L KQ+R+ E E 
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 1605

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            ++ERKQR LAVA++KK+E +L++L+AQ+ +A + ++E +KQLRK+QAQMK+  RE+EE R
Sbjct: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+S+RARR A+Q+RDE+ADE+ N    K+
Sbjct: 1666 ASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKS 1725

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR+RK  LQV++L  EL+AERS + K+++
Sbjct: 1726 ALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDN 1785

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             RQQLERQ +EL+ +L E +   +++ K TI+ALE+K+ Q EEQLEQE +ER  + KLVR
Sbjct: 1786 ARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVR 1845

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            R EK+LKE+ +QVE+ERR ADQ ++Q+EK N R+KQLKRQLEEAEEEA+RA A RR+LQR
Sbjct: 1846 RTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905

Query: 1964 ELEDVTESAESMNREVTTLRNRLRR-GPLTF-TTRTVRQVFRLEEG--VASDEEAEEAQP 2019
            EL+D TE+ E ++REV+TL+NRLRR GP++F ++R+ R+   LE      SD++ E    
Sbjct: 1906 ELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTS 1965

Query: 2020 GSGPSPEPE 2028
                +  P+
Sbjct: 1966 DVNETQPPQ 1974


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 2519 bits (6528), Expect = 0.0
 Identities = 1267/1982 (63%), Positives = 1589/1982 (80%), Gaps = 49/1982 (2%)

Query: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
            Q +W A++LVWVPS+  GFE A+L++E  EEA VEL E+G+++++ +D IQ+MNPPKFSK
Sbjct: 23   QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82

Query: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
             EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK
Sbjct: 83   VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142

Query: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
            RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K
Sbjct: 143  RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202

Query: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            + G           ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 203  DQG-----------ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVG 251

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
            ANIETYLLEKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG  + P
Sbjct: 252  ANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIP 311

Query: 347  GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
            GQ+ +++FQET+E++R++G   EE + +LR++S VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 312  GQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAA 371

Query: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
            QK+  LLG+ VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVL
Sbjct: 372  QKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVL 431

Query: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
            R+N+ALD++ RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 432  RINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEE 491

Query: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
            YQREGI W F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG
Sbjct: 492  YQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQG 551

Query: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
             HPKFQ+P+ L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+  +E+
Sbjct: 552  THPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSEL 611

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
            WKD                                 V+ I+GL+QV+ + +   P   + 
Sbjct: 612  WKD---------------------------------VDRIIGLDQVAGMSETALPGAFKT 638

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            R+GMFRTVGQLYKE L++LMATL NTNP+FVRCI+PNHEK+AGKL+P LVLDQLRCNGVL
Sbjct: 639  RKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVL 698

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
            EGIRICRQGFPNR++FQEFRQRYEILTPN+IPKGFMDGKQAC  MI+ALELD NLYR+GQ
Sbjct: 699  EGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQ 758

Query: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
            SK+FFRAGVLA LEEERDLK+TD+I+ FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 759  SKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAA 818

Query: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
            YLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+ +EL KV+E Q  +   + E++   +QL
Sbjct: 819  YLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQL 878

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
              E+ +L EQL+AE ELCAEAEE R RL A+KQELE +  +LEARV EEEE  + +Q EK
Sbjct: 879  MAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK 938

Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
            K++QQ+IQELE  LE EE ARQKLQLEKVTTEAK+KK EE+ ++LEDQN KL+KE+KLLE
Sbjct: 939  KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998

Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
            DR+AEF++   EEEEK KSL KL+ K+EA I D+E+RLR+EEK RQELEK +R+L+G+S+
Sbjct: 999  DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
            +L +Q+ E Q +  EL+ QL +KEEELQAALAR E+E   +   LK +RE ++ ++E QE
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118

Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
            DLESER +R KAEKQ+RDLGEELEAL+ ELEDTLDST AQQELRSKREQEV  LKKTLEE
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            E + HEA +QE+RQ+H QA+ ELAEQLEQ +R K   EK +  LE E  EL  E+  L  
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
             + + E +R+++E QLQE+Q +  +GER R E A+K+ + Q EL+NV+G L++++SK+ +
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
            L+K+ S+ E+QL D QELLQEE R KL+L ++++ +E E    REQLEEE  A+    ++
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358

Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
            + T  AQ+++ +++ E+  G LE  EE +R+  ++ E L+QR  EK    D+LE+ + RL
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            QQELDD  +DL+ QRQ    LEKKQ+KFDQLLAEEK    +  EER+RAEAE RE+E +A
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
            LSL RALEE  E + ELER N+  R E+E L+SSKDDVGKSVHELE++ R  EQ   +++
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
             Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQGRDE  EE+++QL +Q+R+ E E 
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            ++ERKQR++AVAARKKLE +L++L+A + SA + ++EA+KQLRK+QAQMK+  RE+++TR
Sbjct: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 1658

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             SREEI +Q +E+EK+LK +EAE+++LQEELAA++RA+RQAQQ+RDE+ADE+AN +   A
Sbjct: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
              LEEKR+LE R+ QLEEELEEEQ N+EL+NDR +K  LQ++ + T+L+ ERS + K E+
Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             RQQLERQ +EL+ +L E +   ++++K +I ALE+K+AQ EEQL+ ET+ER  + K VR
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            R EK+LK+V+LQV++ERR A+Q +DQ +K + R+KQLKRQLEEAEEEA RA A RR+LQR
Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898

Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGP 2023
            ELED TE+A++MNREV++L+N+LRRG L F     R++ R   G  SDEE +    G+  
Sbjct: 1899 ELEDATETADAMNREVSSLKNKLRRGDLPFV--VPRRMARKGAGDGSDEEVDGKADGAEA 1956

Query: 2024 SP 2025
             P
Sbjct: 1957 KP 1958


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 2446 bits (6339), Expect = 0.0
 Identities = 1236/1974 (62%), Positives = 1576/1974 (79%), Gaps = 39/1974 (1%)

Query: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86

Query: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146

Query: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206

Query: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            +  +    S  +YGELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207  DTSITQGPS-FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 265

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
            ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P
Sbjct: 266  ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 325

Query: 347  G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
              Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 326  AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 385

Query: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
            QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ 
Sbjct: 386  QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445

Query: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
            R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 446  RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505

Query: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
            YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG
Sbjct: 506  YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565

Query: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
             HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++
Sbjct: 566  SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
            WKD                                 V+ IVGL+Q++ + +   P   + 
Sbjct: 626  WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 652

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+  LVL+QLRCNGVL
Sbjct: 653  KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 712

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
            EGIRICRQGFPNRI+FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYR+GQ
Sbjct: 713  EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 772

Query: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
            SKIFFR GVLA LEEERDLK+TD+I++FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 773  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 832

Query: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
            YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+  ELQK +E QQ++  E+ EL+ + +QL
Sbjct: 833  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 892

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
             EE+  L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+  +Q+Q E+
Sbjct: 893  TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 952

Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
            K++ Q + +LE  LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 953  KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012

Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
            +R+++ ++  AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
            +  EQ+ + Q +  EL+ QL +KEEELQAALAR +DE   +   LK +RE +  +++ QE
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132

Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
            DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST  QQELR+KREQEVT LKK L+E
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K   +K +  LE E ++L  EL  L  
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
            A+QE E ++++LE Q+QE+Q +  DGERARAE  +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
            L+K+++S  +QL D QELLQEETR KL + +++R +E E   L++QL+EE  A++   R 
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372

Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
            + T   QLS+ +++ ++ A  +EA EE ++R  +E E LTQ+  EK    D+LE+ + RL
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            QQELDD  +DL+ QRQLVS LEKKQRKFDQLLAEEK    +  +ER+RAEAE RE+E +A
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
            LSL RALEE  EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R  E    +++
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
             Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE  EE+RRQL +QL + E E 
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            ++ERKQR LA AA+KKLEG+L++L+ Q  SA +G+EEA+KQLRK+QAQMK+  RE+E+ R
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             SR+EIF+  +E+EK+ K LEA++++LQE+LAA++RAR+QA  +++E+A+E+A+    + 
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK   Q E L+ EL+ ERS + K ES
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             RQQLERQ +ELR +L E +   +++ K TIAALE+K+AQ EEQ+EQE RE+  + K ++
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R  A RR+LQR
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912

Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR--LEEGVASDEEAE 2015
            EL++ TES E+M REV  L+++LRRG  T    + R   R  +E    S+EE +
Sbjct: 1913 ELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1966


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 2441 bits (6326), Expect = 0.0
 Identities = 1228/1947 (63%), Positives = 1564/1947 (80%), Gaps = 37/1947 (1%)

Query: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86

Query: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146

Query: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206

Query: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            +  +    S  +YGELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207  DTSITQGPS-FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 265

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
            ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P
Sbjct: 266  ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 325

Query: 347  G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
              Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 326  AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 385

Query: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
            QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ 
Sbjct: 386  QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445

Query: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
            R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 446  RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505

Query: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
            YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG
Sbjct: 506  YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565

Query: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
             HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++
Sbjct: 566  SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
            WKD                                 V+ IVGL+Q++ + +   P   + 
Sbjct: 626  WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 652

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+  LVL+QLRCNGVL
Sbjct: 653  KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 712

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
            EGIRICRQGFPNRI+FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYR+GQ
Sbjct: 713  EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 772

Query: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
            SKIFFR GVLA LEEERDLK+TD+I++FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 773  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 832

Query: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
            YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+  ELQK +E QQ++  E+ EL+ + +QL
Sbjct: 833  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 892

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
             EE+  L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+  +Q+Q E+
Sbjct: 893  TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 952

Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
            K++ Q + +LE  LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 953  KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012

Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
            +R+++ ++  AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
            +  EQ+ + Q +  EL+ QL +KEEELQAALAR +DE   +   LK +RE +  +++ QE
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132

Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
            DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST  QQELR+KREQEVT LKK L+E
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K   +K +  LE E ++L  EL  L  
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
            A+QE E ++++LE Q+QE+Q +  DGERARAE  +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
            L+K+++S  +QL D QELLQEETR KL + +++R +E E   L++QL+EE  A++   R 
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372

Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
            + T   QLS+ +++ ++ A  +EA EE ++R  +E E LTQ+  EK    D+LE+ + RL
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            QQELDD  +DL+ QRQLVS LEKKQRKFDQLLAEEK    +  +ER+RAEAE RE+E +A
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
            LSL RALEE  EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R  E    +++
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
             Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE  EE+RRQL +QL + E E 
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            ++ERKQR LA AA+KKLEG+L++L+ Q  SA +G+EEA+KQLRK+QAQMK+  RE+E+ R
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             SR+EIF+  +E+EK+ K LEA++++LQE+LAA++RAR+QA  +++E+A+E+A+    + 
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK   Q E L+ EL+ ERS + K ES
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             RQQLERQ +ELR +L E +   +++ K TIAALE+K+AQ EEQ+EQE RE+  + K ++
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R  A RR+LQR
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912

Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGP 1990
            EL++ TES E+M REV  L+++LR  P
Sbjct: 1913 ELDEATESNEAMGREVNALKSKLRGPP 1939



 Score =  196 bits (499), Expect = 1e-49
 Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%)

Query: 1142 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1194
            Q+ R+EEE+QA    L + ++        LK L +  + L E     QE L++E     +
Sbjct: 853  QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912

Query: 1195 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1247
            AE+ R       ++L E L  +   LE+  D     Q  R K  Q++ +L++ LEEE   
Sbjct: 913  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 969

Query: 1248 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
             EAA Q+L+     A   + +L +++           K R  LE  +S+L   L+  +  
Sbjct: 970  -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028

Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
             +   + + + E  + E++ R    E++R E  +  ++ + +  +    + + +++   L
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088

Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
              +L+  E +L  A   L +E   K     ++R +E   + L+E L+ E AAR +A ++ 
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148

Query: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1483
            +    +L   +   E+   +    +E R +  +E   L + L E+T + + +++  R++ 
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
             Q +++ T  LEQ ++  + L+K ++  ++  A+    +    + ++  E + ++ EA+ 
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1602
              L     + + AR EL  +   L+ E+E++    ++  GK++           + A D+
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1317

Query: 1603 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1660
             +  ++L+D +    E+ + +L V+ +  + + ER+ LQ + +   E ++ L + +    
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377

Query: 1661 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1713
            ++  D ++K +  A         +K+ + E+E L  Q        ++  K   ++Q ++ 
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437

Query: 1714 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1772
            +L  +++  R    ++ S   + +++   L AE   +  + A   DRA  +A++ ++  A
Sbjct: 1438 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1492

Query: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1825
              +A   L +A  LE K +LE     L+ E+E+  S       N   L    R L  Q+E
Sbjct: 1493 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549

Query: 1826 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1884
             + T+L          E  + +LE  +Q L+G+  E D  AR  +++     L+ +L + 
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1608

Query: 1885 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1944
            E +LE E ++R L+    ++ E  LK++ LQ +   +  ++   QL K   ++K  +R+L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668

Query: 1945 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1990
            E+A              E++A   +A   +LQ +L     + +  + E   L   L    
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1727

Query: 1991 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 2021
            L+       +  RLE  +A  EE  E + G+
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1758


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 2440 bits (6324), Expect = 0.0
 Identities = 1234/1974 (62%), Positives = 1573/1974 (79%), Gaps = 46/1974 (2%)

Query: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86

Query: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146

Query: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206

Query: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            +  +         GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207  DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
            ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P
Sbjct: 259  ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318

Query: 347  G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
              Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 319  AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378

Query: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
            QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ 
Sbjct: 379  QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438

Query: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
            R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439  RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498

Query: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
            YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG
Sbjct: 499  YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558

Query: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
             HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++
Sbjct: 559  SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
            WKD                                 V+ IVGL+Q++ + +   P   + 
Sbjct: 619  WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 645

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+  LVL+QLRCNGVL
Sbjct: 646  KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 705

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
            EGIRICRQGFPNRI+FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYR+GQ
Sbjct: 706  EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 765

Query: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
            SKIFFR GVLA LEEERDLK+TD+I++FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825

Query: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
            YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+  ELQK +E QQ++  E+ EL+ + +QL
Sbjct: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
             EE+  L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+  +Q+Q E+
Sbjct: 886  TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 945

Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
            K++ Q + +LE  LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 946  KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005

Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
            +R+++ ++  AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
            +  EQ+ + Q +  EL+ QL +KEEELQAALAR +DE   +   LK +RE +  +++ QE
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125

Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
            DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST  QQELR+KREQEVT LKK L+E
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K   +K +  LE E ++L  EL  L  
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
            A+QE E ++++LE Q+QE+Q +  DGERARAE  +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
            L+K+++S  +QL D QELLQEETR KL + +++R +E E   L++QL+EE  A++   R 
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365

Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
            + T   QLS+ +++ ++ A  +EA EE ++R  +E E LTQ+  EK    D+LE+ + RL
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            QQELDD  +DL+ QRQLVS LEKKQRKFDQLLAEEK    +  +ER+RAEAE RE+E +A
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
            LSL RALEE  EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R  E    +++
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
             Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE  EE+RRQL +QL + E E 
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            ++ERKQR LA AA+KKLEG+L++L+ Q  SA +G+EEA+KQLRK+QAQMK+  RE+E+ R
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             SR+EIF+  +E+EK+ K LEA++++LQE+LAA++RAR+QA  +++E+A+E+A+    + 
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK   Q E L+ EL+ ERS + K ES
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             RQQLERQ +ELR +L E +   +++ K TIAALE+K+AQ EEQ+EQE RE+  + K ++
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R  A RR+LQR
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905

Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR--LEEGVASDEEAE 2015
            EL++ TES E+M REV  L+++LRRG  T    + R   R  +E    S+EE +
Sbjct: 1906 ELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 2435 bits (6311), Expect = 0.0
 Identities = 1226/1947 (62%), Positives = 1561/1947 (80%), Gaps = 44/1947 (2%)

Query: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86

Query: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146

Query: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206

Query: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            +  +         GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207  DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
            ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P
Sbjct: 259  ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318

Query: 347  G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
              Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 319  AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378

Query: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
            QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ 
Sbjct: 379  QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438

Query: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
            R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439  RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498

Query: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
            YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG
Sbjct: 499  YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558

Query: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
             HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++
Sbjct: 559  SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
            WKD                                 V+ IVGL+Q++ + +   P   + 
Sbjct: 619  WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 645

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+  LVL+QLRCNGVL
Sbjct: 646  KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 705

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
            EGIRICRQGFPNRI+FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYR+GQ
Sbjct: 706  EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 765

Query: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
            SKIFFR GVLA LEEERDLK+TD+I++FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825

Query: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
            YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+  ELQK +E QQ++  E+ EL+ + +QL
Sbjct: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
             EE+  L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+  +Q+Q E+
Sbjct: 886  TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 945

Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
            K++ Q + +LE  LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 946  KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005

Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
            +R+++ ++  AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
            +  EQ+ + Q +  EL+ QL +KEEELQAALAR +DE   +   LK +RE +  +++ QE
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125

Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
            DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST  QQELR+KREQEVT LKK L+E
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K   +K +  LE E ++L  EL  L  
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
            A+QE E ++++LE Q+QE+Q +  DGERARAE  +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
            L+K+++S  +QL D QELLQEETR KL + +++R +E E   L++QL+EE  A++   R 
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365

Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
            + T   QLS+ +++ ++ A  +EA EE ++R  +E E LTQ+  EK    D+LE+ + RL
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            QQELDD  +DL+ QRQLVS LEKKQRKFDQLLAEEK    +  +ER+RAEAE RE+E +A
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
            LSL RALEE  EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R  E    +++
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
             Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE  EE+RRQL +QL + E E 
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            ++ERKQR LA AA+KKLEG+L++L+ Q  SA +G+EEA+KQLRK+QAQMK+  RE+E+ R
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             SR+EIF+  +E+EK+ K LEA++++LQE+LAA++RAR+QA  +++E+A+E+A+    + 
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK   Q E L+ EL+ ERS + K ES
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             RQQLERQ +ELR +L E +   +++ K TIAALE+K+AQ EEQ+EQE RE+  + K ++
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R  A RR+LQR
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905

Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGP 1990
            EL++ TES E+M REV  L+++LR  P
Sbjct: 1906 ELDEATESNEAMGREVNALKSKLRGPP 1932



 Score =  196 bits (499), Expect = 1e-49
 Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%)

Query: 1142 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1194
            Q+ R+EEE+QA    L + ++        LK L +  + L E     QE L++E     +
Sbjct: 846  QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905

Query: 1195 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1247
            AE+ R       ++L E L  +   LE+  D     Q  R K  Q++ +L++ LEEE   
Sbjct: 906  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962

Query: 1248 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
             EAA Q+L+     A   + +L +++           K R  LE  +S+L   L+  +  
Sbjct: 963  -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021

Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
             +   + + + E  + E++ R    E++R E  +  ++ + +  +    + + +++   L
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081

Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
              +L+  E +L  A   L +E   K     ++R +E   + L+E L+ E AAR +A ++ 
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141

Query: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1483
            +    +L   +   E+   +    +E R +  +E   L + L E+T + + +++  R++ 
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
             Q +++ T  LEQ ++  + L+K ++  ++  A+    +    + ++  E + ++ EA+ 
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1602
              L     + + AR EL  +   L+ E+E++    ++  GK++           + A D+
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1310

Query: 1603 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1660
             +  ++L+D +    E+ + +L V+ +  + + ER+ LQ + +   E ++ L + +    
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370

Query: 1661 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1713
            ++  D ++K +  A         +K+ + E+E L  Q        ++  K   ++Q ++ 
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430

Query: 1714 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1772
            +L  +++  R    ++ S   + +++   L AE   +  + A   DRA  +A++ ++  A
Sbjct: 1431 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1485

Query: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1825
              +A   L +A  LE K +LE     L+ E+E+  S       N   L    R L  Q+E
Sbjct: 1486 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542

Query: 1826 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1884
             + T+L          E  + +LE  +Q L+G+  E D  AR  +++     L+ +L + 
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1601

Query: 1885 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1944
            E +LE E ++R L+    ++ E  LK++ LQ +   +  ++   QL K   ++K  +R+L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661

Query: 1945 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1990
            E+A              E++A   +A   +LQ +L     + +  + E   L   L    
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1720

Query: 1991 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 2021
            L+       +  RLE  +A  EE  E + G+
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 1306 bits (3379), Expect = 0.0
 Identities = 735/1943 (37%), Positives = 1156/1943 (59%), Gaps = 65/1943 (3%)

Query: 56   VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113
            V+VP +   F  A +  R+ G+  AE E    G+ + +  DQ+ + NPPKF K EDMA L
Sbjct: 37   VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93

Query: 114  TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173
            T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT  +V  YRGKKR E PPH
Sbjct: 94   TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153

Query: 174  VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
            ++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+     K+   P  
Sbjct: 154  IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213

Query: 234  VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
                  G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYL
Sbjct: 214  ------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267

Query: 294  LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
            LEKSR I Q K E  +HIFYQ+L     +L   LL+    + Y F++ G ++     + E
Sbjct: 268  LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327

Query: 352  LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
                T  +  VLGF+ EE  SM ++  A++ FGN+  K ++  +QA       A K   L
Sbjct: 328  ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387

Query: 412  LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
            +GL   D  + L  PR+KVG +YV K Q  +Q  +A  ALAKA YER+F W+V R+N  L
Sbjct: 388  MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447

Query: 472  D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
            + + PRQ   F+G+LDIAGFEIF  NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 448  ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 505

Query: 531  IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
            I WTF+DFG+DLQ CIDLIE+P    G++++L+EEC FPKATD +F  K+     G    
Sbjct: 506  IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSAN 562

Query: 590  FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
            FQ+PR+++   +A FS++HYAG VDY    WL KN DPLN+ V  L  +S+ +L + ++ 
Sbjct: 563  FQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFA 622

Query: 648  DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
            +         + G+  P   G                                G+ ++G 
Sbjct: 623  N---------YAGADAPIEKGK-------------------------------GKAKKGS 642

Query: 708  -FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGI 766
             F+TV  L++E+L++LM  L +T+P FVRCI+PN  K  G ++  LV+ QLRCNGVLEGI
Sbjct: 643  SFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGI 702

Query: 767  RICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSK 825
            RICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++  EK++ +L++D N Y+ G +K
Sbjct: 703  RICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTK 762

Query: 826  IFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYL 885
            +FF+AG+L  LEE RD +++ II   QA +RG LAR  ++K  +++ +L V+Q N  A++
Sbjct: 763  VFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFM 822

Query: 886  KLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEE 945
             +++W W +L+ K+KPLL+   +++ + +  +E  +++E  ++S     EL+ ++  L +
Sbjct: 823  GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882

Query: 946  ERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKR 1005
            E+  L  Q++AE +  A+AEE   +L   K +LE  V E+  R+ +EEE + ++  +K++
Sbjct: 883  EKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942

Query: 1006 LQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR 1065
            L+    EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L++ 
Sbjct: 943  LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002

Query: 1066 LAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSEL 1125
              +       EE+KV +L K ++K E  + D+E  L +E+K R +LE+ KR+L+G+    
Sbjct: 1003 HQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062

Query: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
            QE +++ +   ++L  +L +K+ EL A  AR EDE    +QL K L+E QA + E +E+L
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122

Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEET 1245
            E+ER AR K EK R DL  ELE +   LE+   +T+ Q E+  KRE E  ++++ LEE T
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1182

Query: 1246 RIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTAR 1305
              HEA    LR++H  ++ EL EQ++  +R K   EK +   + E+ ++ + +  +  A+
Sbjct: 1183 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1242

Query: 1306 QEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLS 1365
               E+  R LE Q+ E + +A + +R+  +   +  + Q E   +S  L+E E+   +L+
Sbjct: 1243 ANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT 1302

Query: 1366 KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 1425
            +   +   QL D +  L+EE +AK AL   +++   +   LREQ EEE  A+    R L 
Sbjct: 1303 RGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLS 1362

Query: 1426 TAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1484
             A +++++WR + E +A    E  EEA+++ A+  +   + +         LE+ + RLQ
Sbjct: 1363 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQ 1422

Query: 1485 QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARAL 1544
             E++D  +D+E+     + L+KKQR FD++LAE K     +  E E ++ E R       
Sbjct: 1423 NEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELF 1482

Query: 1545 SLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRA 1604
             L  A EE  E  E  +R+N+ L+ E+  L       GK++HELE+  +  E    +L++
Sbjct: 1483 KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQS 1542

Query: 1605 QVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERD 1664
             + E E  L   E   LR ++    +K + ER L  +DE  E+ +R   + +   +   D
Sbjct: 1543 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLD 1602

Query: 1665 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRT 1724
             E + R  A+  +KK+EG+L E++ Q++ A +   EA KQ++ +Q+ +K+   ++++   
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR 1662

Query: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
            + +++       E+R   L+AE+  L+  +  ++R+R+ A+Q+  E ++ V   +    +
Sbjct: 1663 ANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTS 1722

Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1844
            ++ +K++++  L QL+ E+EE         ++ +K +     +  EL  E+  SA  E  
Sbjct: 1723 LINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1782

Query: 1845 RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRR 1904
            ++ +E+ I++L+ RL E +  A    K  +  LE+++ + E +LE E +    S K +R+
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842

Query: 1905 AEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1964
            +E+R+KE+  Q EE+R+   +L+D ++K  L+VK  KRQ EEAEE+A+   +  R++Q E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902

Query: 1965 LEDVTESAESMNREVTTLRNRLR 1987
            L++  E A+    +V  LR + R
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSR 1925



 Score =  226 bits (576), Expect = 2e-58
 Identities = 209/959 (21%), Positives = 432/959 (45%), Gaps = 57/959 (5%)

Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS---ELQEQMVEQQQRAEELRA 1141
            KL  K +  +   E R ++    ++E  +LK  L+   +   EL+E+MV   Q   +L+ 
Sbjct: 831  KLYFKIKPLLKSAE-REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQL 889

Query: 1142 QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1201
            Q+  +++ L  A  R +       QL+K+  + +A + E  E LE E     +   ++R 
Sbjct: 890  QVQAEQDNLADAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942

Query: 1202 LGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1258
            L +E   L+ +++D   TL     ++     + + +TE    L+E         + L++ 
Sbjct: 943  LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002

Query: 1259 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQ 1318
            H QAL +L  + ++         K ++ LE +V +L   L   +  R + E+ +R+LE  
Sbjct: 1003 HQQALDDLQAEEDKVN----TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1058

Query: 1319 LQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDA 1378
            L+  Q    D E  + +  E+L++   EL  ++  + + ++   +L K+L   +A++ + 
Sbjct: 1059 LKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEEL 1118

Query: 1379 QELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1438
            +E L+ E  A+  +      +  E   + E+LEE   A        +  +A+  + RR  
Sbjct: 1119 EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178

Query: 1439 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDAT 1491
            EE     EA   A R+   ++      +AE  E +D L+R +++L++E       LDD T
Sbjct: 1179 EEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232

Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LT 1547
             ++EQ  +  + LEK  R  +  + E ++      EE +R+  +   + A+  +    L+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSVNDLTSQRAKLQTENGELS 1288

Query: 1548 RALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT 1607
            R L+E++    +L R       +LE L    ++  K+ + L  A + A    + LR Q  
Sbjct: 1289 RQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYE 1348

Query: 1608 ELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEER 1667
            E  +     +    +    V   +T++E D   R E  EE +++LA++L++AE   +   
Sbjct: 1349 EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVN 1408

Query: 1668 KQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE 1727
             + +     + +L+ E+E+L   +  +        K+ R     + E  ++ EE+++  E
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468

Query: 1728 EIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNL 1780
                    S+K  + L  E+ +L+       E L    R  +  Q++  ++ +++ +   
Sbjct: 1469 S-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521

Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840
            +   + + ++QLE    +L+  LEE +++ E    +  +  L+   +  E+  ER  + K
Sbjct: 1522 TIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEK 1579

Query: 1841 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILS 1898
             E   Q     ++ +       DA  R+R++       +E  L + E QL    R    +
Sbjct: 1580 DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEA 1639

Query: 1899 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1958
             K V+  +  LK+  +Q+++  R  D L++ +     R   L+ +LEE      + +  R
Sbjct: 1640 QKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR 1699

Query: 1959 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
            +  ++EL + +E  + ++ + T+L N+ ++     +         ++E   ++E+A++A
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%)

Query: 918  ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 974
            +L     +  ++ ++V  LQ   + L++ + +L + +RA  +L    A  E     L A 
Sbjct: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684

Query: 975  KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 1018
             +EL  VV + E   ++ E+E  E S ++Q           +KK++   + +L+  +E  
Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744

Query: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1078
             +E    + + +K  T+A M    E+L   +D ++ L + +K +E  + +   +  E E+
Sbjct: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802

Query: 1079 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1137
              +K   K   K EA + ++E+ L  E+K   E  K  R+ +    EL  Q  E ++   
Sbjct: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862

Query: 1138 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1197
             L+  + + + +++A   +AE+        L   R+ Q  L EA+E  +       K   
Sbjct: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922

Query: 1198 QRRDLG 1203
            + RD+G
Sbjct: 1923 KSRDIG 1928


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 1295 bits (3351), Expect = 0.0
 Identities = 760/1955 (38%), Positives = 1133/1955 (57%), Gaps = 64/1955 (3%)

Query: 48   VEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKA 107
            + W  ++ VWVP E   +  A ++ E          +  + L +   ++Q MNPP+F   
Sbjct: 69   IPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLL 128

Query: 108  EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
            EDMA +T LNEASVLHNLR+RY   +IYTYSGLFCV INPYK LP+YT ++V  Y+GK+R
Sbjct: 129  EDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRR 188

Query: 168  HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
             + PPH+YAV + AY  ML++R++QS+L TGESGAGKT NTK+VIQY A VA+   G   
Sbjct: 189  SDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG--- 245

Query: 228  PGVPAS-VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
            PG  A  ++T + G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F  +G +  
Sbjct: 246  PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLAS 305

Query: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSS 345
            A+I++YLLEKSR I Q   E S+H++YQ+L G   +L+  LLL    + Y F + G  + 
Sbjct: 306  ADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITV 365

Query: 346  PGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTA 404
                + E    T  ++ +LGFS +E  +  ++V A+L FGN+  K+++  +QA      +
Sbjct: 366  DNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTES 425

Query: 405  AQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
            A K   L+G+   D  + LL PR++VG +YV K Q+ EQ  FA+ ALAKATY+RLFRWLV
Sbjct: 426  ADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLV 485

Query: 465  LRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
             R+N+ LD + PRQ   F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FN  MFVLEQ
Sbjct: 486  SRINQTLDTKLPRQ--FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQ 543

Query: 524  EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE 583
            EEY+REGI W F+DFGLDLQPCIDLIE+P    G+L++L+EEC FPKA+D SF  K+   
Sbjct: 544  EEYKREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDN 600

Query: 584  QGGH-PKFQRPR---HLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639
              G  P FQ+PR     + QA F V+HYAG V Y    WL KN DPLN+ V  +  +S +
Sbjct: 601  HAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQN 660

Query: 640  RLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPP 699
            RL A ++++         + GS    PP S                           G  
Sbjct: 661  RLLATLYEN---------YAGSCSTEPPKS---------------------------GVK 684

Query: 700  GGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRC 759
              R +   F+TV QL+KE+L++LM  L  T P FVRCIVPN  K  G ++  LVL QLRC
Sbjct: 685  EKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRC 744

Query: 760  NGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNL 818
            NGVLEGIRICRQGFPNR+L+ +FRQRY IL P+AIP   FMD ++A EK++ +L+LD   
Sbjct: 745  NGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQ 804

Query: 819  YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQ 878
            Y+ G +K+FF+AG+L  LEE RD ++  ++   QA +RG L R  +Q+    + AL  +Q
Sbjct: 805  YQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQ 864

Query: 879  RNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQG 938
             N  A+  +++W W +LF K+KPLL+  + +E L A   EL+ ++     +  +  EL+ 
Sbjct: 865  WNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEE 924

Query: 939  RVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQ 998
                + +E+  LA QL+AE +  A+AEE    L   K +LE  V EL  R+ +EEE +  
Sbjct: 925  THVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNAD 984

Query: 999  MQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1058
            +   +++L+    EL+  ++  +    K + EK  TE K+K   E++  L++  ++L+KE
Sbjct: 985  LAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1044

Query: 1059 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1118
            +K L++   +       EE++V +L K +L+ E  + D+E  L +E+K R + E+ KR+L
Sbjct: 1045 KKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKL 1104

Query: 1119 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAAL 1178
            +G+    QE + +  Q  ++L  +L +K+ EL     R EDE    AQ+ K ++E QA  
Sbjct: 1105 EGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA 1164

Query: 1179 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238
             E +E+LE+ER AR + EKQR +   ELE L   LE+   ++  Q+E   KRE E+  L+
Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224

Query: 1239 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAEL 1298
            + LEE    HEA V  LR++  +   EL EQ++  +R +   EK +  L  EV +L A +
Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 1284

Query: 1299 SSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAE 1358
             +L  A+   E+  R  E QL E + +  + +R  A+A+ +  R Q E   +S  L E E
Sbjct: 1285 ETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKE 1344

Query: 1359 SKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARE 1418
                +LS+  +     L + +  L+EE++AK AL   V+A+  +   LREQ EEEA A+ 
Sbjct: 1345 CLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQA 1404

Query: 1419 RAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLE 1477
               R L  A A++++WR + E +A    E  EEA+++ A   +   + +         LE
Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464

Query: 1478 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1537
            + + RLQ E +D T++LE+     + L+KKQR  ++ L E      R  EE  + E E  
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEER-----RRQEEEMQRELEAA 1519

Query: 1538 EREARALS-----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1592
            +RE+R L      L    EE  EA E L+R+N+ L+ E+  L       GKS+ ELE+  
Sbjct: 1520 QRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTK 1579

Query: 1593 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1652
            +  E   ++++A + E E  L   E   LR+++ +  +K + +R L  +DE     RR  
Sbjct: 1580 KALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNH 1639

Query: 1653 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1712
             + +   +   D E + R  A+  +KK+EG+L +L+ Q+  A +   EA    R MQAQ+
Sbjct: 1640 QRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQL 1699

Query: 1713 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMA 1772
            KE     +E +    E+  Q +  E+R   L AE+  L+  L   +R+RR A+Q+  E  
Sbjct: 1700 KEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEAT 1759

Query: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELS 1832
            + +   +     +L +K++LE  L QL  E+EE         ++ +K +     +  EL 
Sbjct: 1760 ERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 1819

Query: 1833 AERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQET 1892
             E+  SA  E  ++ LE+ ++EL+ RL E +  A    K  +  LE+K+ + E +L+ E 
Sbjct: 1820 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQ 1879

Query: 1893 RERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEAS 1952
            ++   + K VR+ E+R+KE+  Q EE+R+   +++D ++K   +VK  KRQ EEAE++A+
Sbjct: 1880 KKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQAN 1939

Query: 1953 RAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
               A  R+ Q EL+D  E A+    +   LR R R
Sbjct: 1940 TNLAKYRKAQHELDDAEERADMAETQANKLRARTR 1974



 Score =  249 bits (637), Expect = 1e-65
 Identities = 234/935 (25%), Positives = 414/935 (44%), Gaps = 60/935 (6%)

Query: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
            R EL  L+  L   + +  EL+E  V   Q   +L  QL  +++ L  A  R        
Sbjct: 902  RAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH------ 955

Query: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221
              L+KS  + +  + E  E LE E         +RR L +E   L+ +++D   TL    
Sbjct: 956  -LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAE 1014

Query: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
             +++    + + +TE    L+E         + L++ H QALG+L  Q E+ R    A  
Sbjct: 1015 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL--QAEEDR--VSALT 1070

Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
            K +L LE +V +L   L   +  R + E+ +R+LE  L+  Q    D  + + +  EKL+
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130

Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401
            +  +EL  +S  + + +    ++ K++   +A+  +    L+EE  A+ A  +RV    A
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE----LEEELEAERAARARVEKQRA 1186

Query: 1402 EAAG----LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1457
            EAA     L E+LEE   A        +  +A+L   RR  EE A   EA   A RR   
Sbjct: 1187 EAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQA 1246

Query: 1458 EAEALTQRLAEKTETVDR----LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1513
            E  A    L E+ +++ R    LE+ +  L+ E+DD   ++E   +  ++ EK  R ++ 
Sbjct: 1247 EGAA---ELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303

Query: 1514 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1573
             L+E K  V     +   A  +    +  +  L+R LEE++    +L R        LE 
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363

Query: 1574 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1633
            L    ++  K+   L  A +      + LR Q  E  +     +    +    V   +++
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423

Query: 1634 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1693
            +E D   R E  EE +++LA +L++AE   +    + +    A+ +L+ E E++  ++  
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLEL-- 1481

Query: 1694 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-- 1751
                 E A      +  + + L R +EE R   EE+  +   +++  +GL  E+ RL+  
Sbjct: 1482 -----ERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536

Query: 1752 -----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEE 1806
                 E L    R  +  Q++  ++ D+V+    S   + + K+ LEG   +++  LEE 
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596

Query: 1807 QSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEED 1863
            +   EL  +  + L +Q+E    +   +R  + K E     R+  +R ++ L+  L   D
Sbjct: 1597 EGALEL--EETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL---D 1651

Query: 1864 AGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERR 1921
            A  RAR++       +E  L   E QL   TR+   +    R  + +LKE     +EE+R
Sbjct: 1652 AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQR 1711

Query: 1922 VADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTT 1981
            +A +L +Q +    R   L  +LEE      + +  RR  ++EL + TE    ++ + T 
Sbjct: 1712 LAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTG 1771

Query: 1982 LRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
            L N+ ++          +    +EE      EAEE
Sbjct: 1772 LLNQKKK----LEADLAQLSGEVEEAAQERREAEE 1802



 Score =  199 bits (507), Expect = 2e-50
 Identities = 241/979 (24%), Positives = 408/979 (41%), Gaps = 183/979 (18%)

Query: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-----LEEERAR 949
            TK K  LQ   Q  +  LQA    +  + + + +  ++V +L+  + Q     ++ ERA+
Sbjct: 1042 TKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAK 1101

Query: 950  --LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
              L   L+   E  A+A + + +L  + ++ +  +S+L  RV +E+    QMQ + K LQ
Sbjct: 1102 RKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1161

Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1067
               +ELE  LEAE  AR +++ ++     ++++  E L   E+     + +R+    R A
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERL---EEAGGASAGQREGCRKREA 1218

Query: 1068 EFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL-------EKLKRRLDG 1120
            E      E EE         L++EAT+A +    RK+ +G  EL       ++++++L+ 
Sbjct: 1219 ELGRLRRELEEAA-------LRHEATVAALR---RKQAEGAAELGEQVDSLQRVRQKLEK 1268

Query: 1121 ESSELQEQM------VEQQQRAEELRAQLGR-----------KEEELQAALA-------R 1156
            E SEL+ ++      VE   RA+    +L R           K EELQ  LA       R
Sbjct: 1269 EKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGR 1328

Query: 1157 AEDEGGARAQLLK---------SLREAQAA--LAEAQEDLESERVARTKAEKQRRDLGEE 1205
             + E G  ++LL+         S  +A AA  L E +  LE E  A++      + L  +
Sbjct: 1329 LQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD 1388

Query: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
             + LR + E+  ++    Q L SK   EV + +   E +       ++E +++    L E
Sbjct: 1389 CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQE 1448

Query: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELS------------------SLQTARQE 1307
              E +E A     + EK +L L+ E  ++  EL                   +L+  R++
Sbjct: 1449 AEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ 1508

Query: 1308 GEQRRRRLELQLQEVQG------RAGDGERARAEAAEKLQRA------------------ 1343
             E+ +R LE   +E +G      R   G     EA E L+R                   
Sbjct: 1509 EEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLS 1568

Query: 1344 ---------------------QAELENVSGALNEAESKTIRLSKELSSTEAQL------- 1375
                                 QA LE   GAL   E+KT+R+  ELS  +A++       
Sbjct: 1569 GKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEK 1628

Query: 1376 ---------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERA 1420
                              Q  L  ETRA+       + ME +   L  QL         A
Sbjct: 1629 DEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688

Query: 1421 GRELQTAQAQLSEWRR-RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERG 1479
                +  QAQL E +  R EE+  A E  E+A+    R A  L   L E    +++ ER 
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQA-LERRASLLAAELEELRAALEQGERS 1747

Query: 1480 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1539
            RR  +QEL +AT  L       + L  +++K +  LA+    V  A +ER  AE + ++ 
Sbjct: 1748 RRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKA 1807

Query: 1540 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 1599
               A  +   L++EQ+    LER  + L               ++V EL+     AEQAA
Sbjct: 1808 ITDAAMMAEELKKEQDTSAHLERMKKTLE--------------QTVRELQARLEEAEQAA 1853

Query: 1600 -NDLRAQVTELEDELTAAEDAKLR-LEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLR 1657
                + QV +LE        AK+R LE  + A + +H   L+G         R+  ++++
Sbjct: 1854 LRGGKKQVQKLE--------AKVRELEAELDAEQKKHAEALKGV--------RKHERRVK 1897

Query: 1658 DAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR 1717
            +   + +E+RK          KL+ +++  K Q   A Q     + + RK Q ++ +   
Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957

Query: 1718 EVEETRTSREEIFSQNRES 1736
              +   T   ++ ++ R++
Sbjct: 1958 RADMAETQANKLRARTRDA 1976


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1293 bits (3345), Expect = 0.0
 Identities = 722/1944 (37%), Positives = 1151/1944 (59%), Gaps = 54/1944 (2%)

Query: 52   ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
            A+  V+V      F    ++     +  V+  E G  L +  DQ+  MNPPK+ K EDMA
Sbjct: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92

Query: 112  ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
             +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152

Query: 172  PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
            PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212

Query: 232  ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
              +     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IET
Sbjct: 213  GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268

Query: 292  YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
            YLLEKSR + Q K E S+HIFYQ+      +L   LL+    + Y F++ G  S     +
Sbjct: 269  YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328

Query: 350  RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
            +E    T  ++ +LGF++EE +S+ ++  AV+ +GN+  K+++  +QA       A K  
Sbjct: 329  QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388

Query: 410  RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
             L  L   D  +AL  PR+KVG +YV K QT EQ   A+ ALAKA YE++F W+V R+N+
Sbjct: 389  YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448

Query: 470  ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
             LD + PRQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 449  QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506

Query: 529  EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
            EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+  Q  G  
Sbjct: 507  EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563

Query: 588  PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
              FQ+P+ ++ +A+  F+++HYAG VDY    WL KN DPLN+ V  L  +S  +  A++
Sbjct: 564  ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
            +                                     G    E   + G    GG+ + 
Sbjct: 624  FS------------------------------------GAQTAEGEGAGGGAKKGGKKKG 647

Query: 706  GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
              F+TV  L++E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEG
Sbjct: 648  SSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEG 707

Query: 766  IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
            IRICR+GFP+RIL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++++D   Y+ G +
Sbjct: 708  IRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHT 767

Query: 825  KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
            K+FF+AG+L  LEE RD K+  +I   QA  RG+LAR  +Q+  +++ A+  +Q N  ++
Sbjct: 768  KVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSF 827

Query: 885  LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
            + ++HW W +LF K+KPLL+    ++ +    +E QK+++   +S  +  EL+ ++  L 
Sbjct: 828  MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLL 887

Query: 945  EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
            +E+  L  Q++AEAE  A+AEE   +L   K +LE  + E+  R  +EEE + ++  +K+
Sbjct: 888  KEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 947

Query: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
            +L+    EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L++
Sbjct: 948  KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1007

Query: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
               +       EE+KV +L K ++K E  + D+E  L +E+K R +LE+ KR+L+G+   
Sbjct: 1008 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKL 1067

Query: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
             QE +++ +   ++L  +L +KE E+    ++ EDE     QL K ++E QA + E +E+
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127

Query: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
            +E+ER +R KAEKQR DL  ELE +   LE+   +T+AQ E+  KRE E  ++++ LEE 
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187

Query: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
            T  HEA    LR++H  ++ EL EQ++  +R K   EK +  ++ E+ +L + + ++  A
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247

Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
            +   E+  R LE QL E++ +  + +R   +   +  R Q E    S  L+E E+   +L
Sbjct: 1248 KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQL 1307

Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
            S+   +   Q+ + +  L+EE +AK AL   +++   +   LREQ EEE  ++    R L
Sbjct: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367

Query: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
              A  ++++WR + E +A    E  EEA+++ A+  +A  + +         LE+ ++RL
Sbjct: 1368 SKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            Q E++D  +D+E+     + L+KKQR FD++LAE K        E E ++ E R      
Sbjct: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
              +  A EE  +  E L+R+N+ L+ E+  L     + GK +HELE+  +  EQ   +L+
Sbjct: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
            A + E E  L   E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   +   
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTL 1607

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            D E + R  A+  +KK+EG+L E++ Q+  A +   EA++  R  Q  +K+    +++  
Sbjct: 1608 DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDAL 1667

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             S+E++  Q    E+R   L+AE+  L+  L  ++R+R+ A+Q+  + ++ V   +    
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            +++  K++LE  + Q++ E+E+    +    ++ +K +     +  EL  E+  SA  E 
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             ++ +E+ +++L+ RL E +  A    K  I  LE+++ + E ++E E +    + K +R
Sbjct: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + E+R+KE+  Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   A  R+LQ 
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907

Query: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
            ELE+  E A+    +V  LR + R
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSR 1931



 Score =  224 bits (572), Expect = 5e-58
 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)

Query: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
            ++E +K+K  L   + +  EL+E+MV   +   +L+ Q+  + E L  A  R +      
Sbjct: 859  KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912

Query: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221
             QL+K+  + +A + E  E  E E     +   ++R L +E   L+ +++D   TL    
Sbjct: 913  -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971

Query: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
             ++     + + +TE    L+E         + L++ H Q L +L  + ++         
Sbjct: 972  KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027

Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
            K ++ LE +V +L   L   +  R + E+ +R+LE  L+  Q    D E  + +  EKL+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087

Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401
            + + E+ N+   + + ++  I+L K++   +A++ + +E ++ E  ++     +   +  
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147

Query: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461
            E   + E+LEE   A        +  +A+  + RR  EE     EA     R+   ++  
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205

Query: 1462 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1519
                +AE  E +D L+R +++L++E  +  M+++     V T+ K +   +++    E++
Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261

Query: 1520 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
             + L++ EE ++       A+    +  +   +R L+E++    +L R  +A   ++E L
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321

Query: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634
                ++  K+ + L  A + +    + LR Q  E ++     + A  +    V   +T++
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381

Query: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694
            E D   R E  EE +++LA++L+ AE   +    +       +++L+ E+E+L   +   
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441

Query: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1751
                    K+ R     + E  ++ EET    E        S+K  + L  E+ +++   
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494

Query: 1752 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
                ++L    R  +  QQ+  ++ +++A G      + + K+Q+E    +L+  LEE +
Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554

Query: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
            ++ E    +  ++ L++  + +E+  +R  + K E   Q     I+ +       DA  R
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612

Query: 1868 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1925
            +R+        +E  L + E QL    R    + +  R  +  LK+  + +++  R  + 
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672

Query: 1926 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1985
            L++QL     R   L+ ++EE      + +  R+  ++EL D +E  + ++ + T+L N 
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732

Query: 1986 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
             ++     +         L+E   ++E+A++A
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764



 Score =  191 bits (486), Expect = 5e-48
 Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%)

Query: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
            TK K  LQ   Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058

Query: 948  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
             +L   L+   E   + E  + +L  + ++ E  +S L++++ +E+    Q+Q + K LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118

Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
              I+ELE  +EAE  +R K + ++     ++++  E L            + + + ++  
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178

Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
            K R+ LE+   +  + AA           E  E++ +L +++ K E         I D+ 
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238

Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
              +    K +  LEK+ R L+ + SEL+ +  EQQ+   +L AQ GR + E      + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298

Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
            ++    +QL +  +     + E +  LE E  A+       +    + + LR + E+  +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358

Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
            S    Q   SK   EV + +   E +       ++E +++  Q L    E +E       
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418

Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
            + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  +   A  EA++
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477

Query: 1339 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
            K  R+   EL  +  A  E+  +   L +E  + + ++ D  E + E  +    L    +
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537

Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
             +E E   L+  LEE  A+ E    ++   Q +L++ +   + + A   E  ++ +R   
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597

Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
            R  E++   L  +  + +   R +++++ +L++  + L    ++ +   +  R    +L 
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657

Query: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1571
            + +  +  A+  +E  + +    E RA  L   +EE +   E+ ER  +    EL     
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717

Query: 1572 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1615
                      +L+++K     D+ +   E+E   + A  A    +  +T+   + +EL  
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777

Query: 1616 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1667
             +D    LE   + ++ Q  +DLQ R DEA       G+++ ++L  ++R+ E E + E+
Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836

Query: 1668 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1706
            K+   AV   +K E  ++EL                     +A++ S  +  EEA +Q  
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 1707 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
               A+ ++L  E+EE     +   ++++ ++ R+K  E     + EE
Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1293 bits (3345), Expect = 0.0
 Identities = 722/1944 (37%), Positives = 1151/1944 (59%), Gaps = 54/1944 (2%)

Query: 52   ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
            A+  V+V      F    ++     +  V+  E G  L +  DQ+  MNPPK+ K EDMA
Sbjct: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92

Query: 112  ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
             +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152

Query: 172  PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
            PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212

Query: 232  ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
              +     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IET
Sbjct: 213  GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268

Query: 292  YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
            YLLEKSR + Q K E S+HIFYQ+      +L   LL+    + Y F++ G  S     +
Sbjct: 269  YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328

Query: 350  RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
            +E    T  ++ +LGF++EE +S+ ++  AV+ +GN+  K+++  +QA       A K  
Sbjct: 329  QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388

Query: 410  RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
             L  L   D  +AL  PR+KVG +YV K QT EQ   A+ ALAKA YE++F W+V R+N+
Sbjct: 389  YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448

Query: 470  ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
             LD + PRQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 449  QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506

Query: 529  EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
            EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+  Q  G  
Sbjct: 507  EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563

Query: 588  PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
              FQ+P+ ++ +A+  F+++HYAG VDY    WL KN DPLN+ V  L  +S  +  A++
Sbjct: 564  ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
            +                                     G    E   + G    GG+ + 
Sbjct: 624  FS------------------------------------GAQTAEGEGAGGGAKKGGKKKG 647

Query: 706  GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
              F+TV  L++E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEG
Sbjct: 648  SSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEG 707

Query: 766  IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
            IRICR+GFP+RIL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++++D   Y+ G +
Sbjct: 708  IRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHT 767

Query: 825  KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
            K+FF+AG+L  LEE RD K+  +I   QA  RG+LAR  +Q+  +++ A+  +Q N  ++
Sbjct: 768  KVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSF 827

Query: 885  LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
            + ++HW W +LF K+KPLL+    ++ +    +E QK+++   +S  +  EL+ ++  L 
Sbjct: 828  MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLL 887

Query: 945  EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
            +E+  L  Q++AEAE  A+AEE   +L   K +LE  + E+  R  +EEE + ++  +K+
Sbjct: 888  KEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 947

Query: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
            +L+    EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L++
Sbjct: 948  KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1007

Query: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
               +       EE+KV +L K ++K E  + D+E  L +E+K R +LE+ KR+L+G+   
Sbjct: 1008 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKL 1067

Query: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
             QE +++ +   ++L  +L +KE E+    ++ EDE     QL K ++E QA + E +E+
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127

Query: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
            +E+ER +R KAEKQR DL  ELE +   LE+   +T+AQ E+  KRE E  ++++ LEE 
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187

Query: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
            T  HEA    LR++H  ++ EL EQ++  +R K   EK +  ++ E+ +L + + ++  A
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247

Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
            +   E+  R LE QL E++ +  + +R   +   +  R Q E    S  L+E E+   +L
Sbjct: 1248 KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQL 1307

Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
            S+   +   Q+ + +  L+EE +AK AL   +++   +   LREQ EEE  ++    R L
Sbjct: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367

Query: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
              A  ++++WR + E +A    E  EEA+++ A+  +A  + +         LE+ ++RL
Sbjct: 1368 SKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            Q E++D  +D+E+     + L+KKQR FD++LAE K        E E ++ E R      
Sbjct: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
              +  A EE  +  E L+R+N+ L+ E+  L     + GK +HELE+  +  EQ   +L+
Sbjct: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
            A + E E  L   E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   +   
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTL 1607

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            D E + R  A+  +KK+EG+L E++ Q+  A +   EA++  R  Q  +K+    +++  
Sbjct: 1608 DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDAL 1667

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
             S+E++  Q    E+R   L+AE+  L+  L  ++R+R+ A+Q+  + ++ V   +    
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            +++  K++LE  + Q++ E+E+    +    ++ +K +     +  EL  E+  SA  E 
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             ++ +E+ +++L+ RL E +  A    K  I  LE+++ + E ++E E +    + K +R
Sbjct: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + E+R+KE+  Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   A  R+LQ 
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907

Query: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
            ELE+  E A+    +V  LR + R
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSR 1931



 Score =  224 bits (572), Expect = 5e-58
 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)

Query: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
            ++E +K+K  L   + +  EL+E+MV   +   +L+ Q+  + E L  A  R +      
Sbjct: 859  KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912

Query: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221
             QL+K+  + +A + E  E  E E     +   ++R L +E   L+ +++D   TL    
Sbjct: 913  -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971

Query: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
             ++     + + +TE    L+E         + L++ H Q L +L  + ++         
Sbjct: 972  KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027

Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
            K ++ LE +V +L   L   +  R + E+ +R+LE  L+  Q    D E  + +  EKL+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087

Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401
            + + E+ N+   + + ++  I+L K++   +A++ + +E ++ E  ++     +   +  
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147

Query: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461
            E   + E+LEE   A        +  +A+  + RR  EE     EA     R+   ++  
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205

Query: 1462 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1519
                +AE  E +D L+R +++L++E  +  M+++     V T+ K +   +++    E++
Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261

Query: 1520 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
             + L++ EE ++       A+    +  +   +R L+E++    +L R  +A   ++E L
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321

Query: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634
                ++  K+ + L  A + +    + LR Q  E ++     + A  +    V   +T++
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381

Query: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694
            E D   R E  EE +++LA++L+ AE   +    +       +++L+ E+E+L   +   
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441

Query: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1751
                    K+ R     + E  ++ EET    E        S+K  + L  E+ +++   
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494

Query: 1752 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
                ++L    R  +  QQ+  ++ +++A G      + + K+Q+E    +L+  LEE +
Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554

Query: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
            ++ E    +  ++ L++  + +E+  +R  + K E   Q     I+ +       DA  R
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612

Query: 1868 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1925
            +R+        +E  L + E QL    R    + +  R  +  LK+  + +++  R  + 
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672

Query: 1926 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1985
            L++QL     R   L+ ++EE      + +  R+  ++EL D +E  + ++ + T+L N 
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732

Query: 1986 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
             ++     +         L+E   ++E+A++A
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764



 Score =  191 bits (486), Expect = 5e-48
 Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%)

Query: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
            TK K  LQ   Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058

Query: 948  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
             +L   L+   E   + E  + +L  + ++ E  +S L++++ +E+    Q+Q + K LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118

Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
              I+ELE  +EAE  +R K + ++     ++++  E L            + + + ++  
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178

Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
            K R+ LE+   +  + AA           E  E++ +L +++ K E         I D+ 
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238

Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
              +    K +  LEK+ R L+ + SEL+ +  EQQ+   +L AQ GR + E      + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298

Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
            ++    +QL +  +     + E +  LE E  A+       +    + + LR + E+  +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358

Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
            S    Q   SK   EV + +   E +       ++E +++  Q L    E +E       
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418

Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
            + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  +   A  EA++
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477

Query: 1339 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
            K  R+   EL  +  A  E+  +   L +E  + + ++ D  E + E  +    L    +
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537

Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
             +E E   L+  LEE  A+ E    ++   Q +L++ +   + + A   E  ++ +R   
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597

Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
            R  E++   L  +  + +   R +++++ +L++  + L    ++ +   +  R    +L 
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657

Query: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1571
            + +  +  A+  +E  + +    E RA  L   +EE +   E+ ER  +    EL     
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717

Query: 1572 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1615
                      +L+++K     D+ +   E+E   + A  A    +  +T+   + +EL  
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777

Query: 1616 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1667
             +D    LE   + ++ Q  +DLQ R DEA       G+++ ++L  ++R+ E E + E+
Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836

Query: 1668 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1706
            K+   AV   +K E  ++EL                     +A++ S  +  EEA +Q  
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 1707 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
               A+ ++L  E+EE     +   ++++ ++ R+K  E     + EE
Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 1291 bits (3340), Expect = 0.0
 Identities = 726/1912 (37%), Positives = 1129/1912 (59%), Gaps = 58/1912 (3%)

Query: 84   ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143
            E G  L +  DQ+  MNPPK+ K EDMA +T L+E  VL+NL+ERY + +IYTYSGLFCV
Sbjct: 67   EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126

Query: 144  VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203
             +NPYK LP+Y   +V  YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG
Sbjct: 127  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186

Query: 204  KTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVK 263
            KT NTK+VIQY A +A + + +K+       S    G LE Q++ ANP+LEAFGNAKTV+
Sbjct: 187  KTVNTKRVIQYFATIAVTGEKKKDE------SGKMQGTLEDQIISANPLLEAFGNAKTVR 240

Query: 264  NDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQL 323
            NDNSSRFGKFIRI+F   G +  A+IETYLLEKSR   Q K E S+HIFYQ+       L
Sbjct: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300

Query: 324  KADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVL 381
               LL+    + Y F++ G  + P   ++E    T  ++ +LGF+ EE +S+ ++  AV+
Sbjct: 301  IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360

Query: 382  QFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTK 441
             +GN+  K+++  +QA       A K   L  L   D  +AL  PR+KVG +YV K QT 
Sbjct: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420

Query: 442  EQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQ 500
            +Q   A+ ALAKA YE++F W+V R+N+ LD + PRQ   F+G+LDIAGFEIF  NS EQ
Sbjct: 421  QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQ 478

Query: 501  LCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLA 560
            LCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL  CI+LIE+P    G+ +
Sbjct: 479  LCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFS 535

Query: 561  LLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANE 617
            +L+EEC FPKATD SF  K+  Q  G    FQ+P+ ++ +A+  FS++HYAG VDY    
Sbjct: 536  ILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITG 595

Query: 618  WLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAI 677
            WL KN DPLND V  L  +S  +  A ++                  S   SAE  SSA 
Sbjct: 596  WLDKNKDPLNDTVVGLYQKSAMKTLASLF------------------STYASAEADSSA- 636

Query: 678  SPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 737
                                  G + +   F+TV  L++E+L++LM  L +T+P FVRCI
Sbjct: 637  --------------------KKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCI 676

Query: 738  VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 797
            +PN  K  G +E  LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L  +AIP+G
Sbjct: 677  IPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEG 736

Query: 798  -FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 856
             F+D K+A EK++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  II   QA  R
Sbjct: 737  QFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCR 796

Query: 857  GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 916
            G+L R  +QK  Q++ AL  +Q N  A++ ++HW W +LF K+KPLL+    ++ +    
Sbjct: 797  GFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMK 856

Query: 917  QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 976
            +E QK ++   +S  +  EL+ ++  L +E+  L  Q+++EA+  A+AEE   +L   K 
Sbjct: 857  EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKI 916

Query: 977  ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1036
            +LE  + E+  R  EEEE + ++  +K++L+    EL+  ++  E    K++ EK  TE 
Sbjct: 917  QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976

Query: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096
            K+K   E++  L++  +KLSKE+K L++   +       EE+KV  L K + K E  + D
Sbjct: 977  KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036

Query: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156
            +E  L +E+K R +LE+ KR+L+G+    QE  ++ +   ++L  +L +KE E+   +++
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096

Query: 1157 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1216
             EDE     QL K ++E QA + E  E++E+ER +R KAEKQR DL  ELE +   LE+ 
Sbjct: 1097 IEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156

Query: 1217 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1276
              +T+AQ EL  KRE E  +L++ LEE T  HEA V  LR++H  ++ EL EQ++  +R 
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRV 1216

Query: 1277 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1336
            K   EK +  L+ E  +L +   ++  A+   E+  R LE Q+ E++ +  + +R   + 
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDL 1276

Query: 1337 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1396
              +  R Q E    S  L+E ++   +LS+   ++  Q+ + +  L+EET+AK AL   +
Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336

Query: 1397 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRA 1455
            ++   +   LREQ EEE   +    R L  A +++++WR + E +A    E  EEA+++ 
Sbjct: 1337 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396

Query: 1456 AREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1515
            A+  +   + +         LE+ ++RLQ E++D  +D+E+     + L+KKQR FD++L
Sbjct: 1397 AQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL 1456

Query: 1516 AEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1575
            +E K        E E ++ E R        +    EE  +  E L R+N+ L+ E+  L 
Sbjct: 1457 SEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516

Query: 1576 SSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHE 1635
                + GK +HELE+  +  EQ   +++A + E E  L   E   LR+++ +  +K++ +
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576

Query: 1636 RDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAG 1695
            R +  +DE  ++ +R   + +   +   D E + R  A+  +KK+EG+L E++ Q+  A 
Sbjct: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636

Query: 1696 QGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELA 1755
            +   E+++  R  Q  +KE    +++    +E++  Q    E+R   L+AE+  L   L 
Sbjct: 1637 RLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLE 1696

Query: 1756 ASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLND 1815
             ++R+R+ A+Q+  + ++ V   +    +++  K++LE  + QL+ E+EE    S    +
Sbjct: 1697 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE 1756

Query: 1816 RYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIA 1875
            + +K +     +  EL  E+  SA  E  ++ LE+ +++L+ RL E +  A    K  I 
Sbjct: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1816

Query: 1876 ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNL 1935
             LE+++ + E ++E E +    + K +R+ E+R+KE+  Q EE+R+   +L+D ++K   
Sbjct: 1817 KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQA 1876

Query: 1936 RVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
            +VK  KRQ EEAEE+++   +  R+LQ ELE+  E A+    +V  LR + R
Sbjct: 1877 KVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928



 Score =  227 bits (579), Expect = 8e-59
 Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%)

Query: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
            +K K  LQ T Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055

Query: 948  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
             +L   L+   E   + E  + +L  + ++ E  +S L +++ +E+    Q+Q + K LQ
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115

Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1067
              I+EL   +EAE  +R K + ++     ++++  E L   E+     S + +L + R A
Sbjct: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172

Query: 1068 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1105
            EF     + EE        +  LR K+  ++A++          + +L KE+        
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232

Query: 1106 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1155
                      K +  LEK+ R L+ + SEL+ +  EQQ+   +L AQ  R + E      
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292

Query: 1156 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1215
            + +++    +QL +S + +   + E +  LE E  A+       +    + + LR + E+
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352

Query: 1216 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1275
              +     Q   SK   EV + +   E +       ++E +++  Q L E  E +E    
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412

Query: 1276 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1335
               + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  + + A  E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471

Query: 1336 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1394
            A++K  R+   EL  V     E+  +   L +E  + + ++ D  E + E  +    L  
Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531

Query: 1395 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1454
              + +E E   ++  LEE  A+ E    ++   Q +L++ +   +               
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576

Query: 1455 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1514
                     +++AEK E +D+L+R   R+ + +  +T+D E + +  +   KK+ + D  
Sbjct: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626

Query: 1515 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1568
              E     A  L A   R     +G  +E + L L  AL  +++ +E+L   ER+   L+
Sbjct: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685

Query: 1569 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1628
            AE+E L ++       + + ER+ ++AEQ   D   +V  L  + T+  + K +LE  V 
Sbjct: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738

Query: 1629 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1685
             L+++ E  +Q    A E+ +    K + DA +  +E +K++  +      +K LE  ++
Sbjct: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794

Query: 1686 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1744
            +L+ ++  A Q   +   KQ++K++A+++EL  EVE  +    E     R+ E+R+K L 
Sbjct: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854

Query: 1745 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1797
             +       VLRLQ+ L    +A+ ++ + + E A+E +N NLSK               
Sbjct: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900

Query: 1798 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1834
            +L+ ELEE +  +++   +  KL ++   + T++SAE
Sbjct: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937



 Score =  219 bits (557), Expect = 3e-56
 Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%)

Query: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
            K+K L    LK   T  +M     + +K + EL K     + +  EL+E+MV   +   +
Sbjct: 838  KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889

Query: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
            L+ Q+  + + L  A  R E       QL+K+  + +A + E  E  E E     +   +
Sbjct: 890  LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942

Query: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
            +R L +E   L+ +++D   TL     ++     + + +TE    L+E         + L
Sbjct: 943  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002

Query: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
            ++ H Q L +L  + ++         K +  LE +V +L   L   +  R + E+ +R+L
Sbjct: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058

Query: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
            E  L+  Q    D E  + +  EKL++ + E+ N+   + + ++  I+L K++   +A++
Sbjct: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118

Query: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
             +  E ++ E  ++     +   +  E   + E+LEE   A        +  +A+  + R
Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178

Query: 1436 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1492
            R  EE     EA   A R+   ++      +AE  E +D L+R +++L++E  +  M   
Sbjct: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232

Query: 1493 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1548
            DL    + +S  +    K  + L ++ + +    EE++R      A+    +  A   +R
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292

Query: 1549 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
             L+E+     +L R  +A   ++E L    ++  K+ + L  A + +    + LR Q  E
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352

Query: 1609 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1668
             ++     + A  +    V   +T++E D   R E  EE +++LA++L++AE   +    
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412

Query: 1669 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1728
            +       +++L+ E+E+L   +  +        K+ R     + E  ++ EET+   E 
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472

Query: 1729 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1788
               ++R     L  ++       ++L    R  +  QQ+  ++ +++A G      + + 
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532

Query: 1789 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1848
            K+Q+E    +++  LEE +++ E    +  ++ L++  + +E+  +R  + K E   Q  
Sbjct: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590

Query: 1849 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1906
                + +       DA  R+R+        +E  L + E QL    R    S +  R  +
Sbjct: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650

Query: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1966
              LKE  L +++  R  + L++QL     R   L+ ++EE      + +  R+  ++EL 
Sbjct: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710

Query: 1967 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
            D +E  + ++ + T+L N  ++    ++     V +V  ++E   ++E+A++A
Sbjct: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 1288 bits (3333), Expect = 0.0
 Identities = 730/1944 (37%), Positives = 1148/1944 (59%), Gaps = 59/1944 (3%)

Query: 52   ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
            A+   +V      +    ++   + +  VE  E  R L +  + +  MNPPKF + EDMA
Sbjct: 34   AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92

Query: 112  ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
             LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y   +VE YRGKKR E P
Sbjct: 93   MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152

Query: 172  PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
            PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++    K+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK--- 209

Query: 232  ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
                +   G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IET
Sbjct: 210  ---DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266

Query: 292  YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
            YLLEKSR   Q K E S+HIFYQ+L     +L   LL+    + Y F++ G        +
Sbjct: 267  YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDD 326

Query: 350  RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
             E    T  ++ +LGF+ EE   + ++  AV+ +GN+  K+++  +QA       A K  
Sbjct: 327  AEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTA 386

Query: 410  RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
             L+GL  +D  +AL  PR+KVG +YV K QT +Q   A+ AL+K+ YE+LF W+V R+N+
Sbjct: 387  YLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQ 446

Query: 470  ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
             LD + PRQ   F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 447  QLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 504

Query: 529  EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
            EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+  Q  G  
Sbjct: 505  EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 561

Query: 588  PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
              FQ+P+ ++ +A+  FS++HYAG VDY  + WL KN DPLN+ V  L  +S++RL A +
Sbjct: 562  NNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL 621

Query: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
            +              +F  +   S                 G ++V+         + + 
Sbjct: 622  Y-------------ATFATADADS-----------------GKKKVA---------KKKG 642

Query: 706  GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
              F+TV  L++E+L++LM+ L  T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEG
Sbjct: 643  SSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEG 702

Query: 766  IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
            IRICR+GFPNRIL+ +F+QRY +L  +AIP+G F+D K+ACEK++ ++++D   Y+ G +
Sbjct: 703  IRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHT 762

Query: 825  KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
            K+FF+AG+L  LEE RD ++  +I   QA  RG+L R  FQK  Q++ ++  +Q N  ++
Sbjct: 763  KVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSF 822

Query: 885  LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
            + ++HW W +LF K+KPLL+    ++ +    +E QK ++   +S  +  EL+ ++  L 
Sbjct: 823  MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLV 882

Query: 945  EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
            +E+  L  Q++AE+E   +AEE   +L   K +LE  + E+  R  +EEE + ++  +K+
Sbjct: 883  QEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKR 942

Query: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
            +L+    EL+  ++  E    K++ EK  TE K+K   E+L  L++  +KL++E+K L++
Sbjct: 943  KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 1002

Query: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
               +       EE+KV SLNK + K E  + D+E  L +E+K R +LE+ KR+L+G+   
Sbjct: 1003 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 1062

Query: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
             QE +++ +   ++L  +L +K+ E     ++ EDE     Q  K ++E QA + E +E+
Sbjct: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 1122

Query: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
            +E+ER  R K EKQR D   ELE L   LE+    T+ Q EL  KRE E  +L++ LEE 
Sbjct: 1123 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEA 1182

Query: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
            T  HEA V  LR++H  ++ EL EQ++  +R K   EK +   + E+ +L + + S+  +
Sbjct: 1183 TLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKS 1242

Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
            +   E+  R LE QL E +G+  + +R+ +E   +  R Q E   +S  L E ES   +L
Sbjct: 1243 KANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQL 1302

Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
            S+   +   Q  + +  L+EE +AK AL   +++   +   LREQ EEE   +    R L
Sbjct: 1303 SRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1362

Query: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
              A +++++WR + E +A    E  EEA+++ A+  +   +++         LE+ ++RL
Sbjct: 1363 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL 1422

Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
            Q E++D  +D+E+   L + L+KKQR FD++LAE K     +  E E +  E R      
Sbjct: 1423 QGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 1482

Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
              L  A EE  +  E ++R+N+ L  E+  L     + GK++HELE++ +  E    D++
Sbjct: 1483 FKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQ 1542

Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
              + E E  L   E   LR+++ +  +K++ +R +  +DE  E+ +R   + +   +   
Sbjct: 1543 LALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602

Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
            D E + R  A+  +KK+EG+L E++ Q++ A +   E +K LR +Q Q+K+    +++  
Sbjct: 1603 DAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDAL 1662

Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
              +E++  Q    E+R   L+AEV  L+  L  ++RAR+ A+Q+  +  + V   +    
Sbjct: 1663 RGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 1722

Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
            +++  K++LE  L QL+ E+E+   ++    ++ +K +     +  EL  E+  SA  E 
Sbjct: 1723 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1782

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
             ++ LE+ +++L+ RL E +  A    K  I  LE+++ + E +LE E ++   S K +R
Sbjct: 1783 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842

Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
            + E+R+KE+  Q EE+R+   +L+D ++K  ++VK  KRQ EEA+E+A+      R+ Q 
Sbjct: 1843 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1902

Query: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
            ELE+  E A+    +V  LR + R
Sbjct: 1903 ELEEAEERADIAESQVNKLRAKTR 1926



 Score =  145 bits (365), Expect = 5e-34
 Identities = 188/868 (21%), Positives = 357/868 (41%), Gaps = 172/868 (19%)

Query: 885  LKLRHWQWWRLFTKVKPL----LQVTRQDEVLQARAQELQ-----------KVQELQQQS 929
            LK + +++ +L +KV+      LQ  ++ + LQAR +EL+           K ++ +   
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140

Query: 930  AREVGELQGRV--------AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 981
            ARE+ EL  R+         Q+E  + R AE L+   +L     +    +AA +++    
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200

Query: 982  VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEA 1036
            V+EL  ++   +   ++++ EK   +  I +L + +E+   ++  L+     LE   +EA
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260

Query: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096
            + K  E     ++   S+L+ ++  L+    E S Q  E+E  V  L++ +  +     +
Sbjct: 1261 RGKNEE-----IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315

Query: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156
            ++ +L +E K +  L    +    +   L+EQ  E+Q+   EL+  L +   E+     +
Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375

Query: 1157 AEDEGGARAQLLKSLREAQAA-LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1215
             E +   R + L+  ++  A  L +++E +E+        EK ++ L  E+E L  ++E 
Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435

Query: 1216 T------LDSTNAQ-----QELRSKREQEVTELKKTLEEETRI----------HEAAVQE 1254
                   LD           E ++K E+   EL+ +L+E   +          +E A+ +
Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495

Query: 1255 LR------QRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1308
            L       +   Q + +L EQ+ +  +     EK+R  +E E ++++  L   + A +  
Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555

Query: 1309 EQRRRRLELQLQEVQGR----------------------------AGDGE-RARAEAAEK 1339
            E +  R++L+L +V+                              A D E R+R EA   
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615

Query: 1340 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL------QEETRAKLALG 1393
             ++ + +L  +   L+ A  +     K L S + QL D Q  L      QE+ + +LA+ 
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675

Query: 1394 SR-VRAMEAEAAGLREQLEEEAAARERAGREL----------QTAQAQLSEWRRRQEEEA 1442
             R    ++AE   LR  LE+   AR+ A +EL           T    L   +++ E + 
Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735

Query: 1443 GALEA-----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
              L++            EE  ++A  +A  + + L ++ +T   LER ++ L+Q + D  
Sbjct: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795

Query: 1492 MDLEQQRQLVSTLEKKQ-----------------------------RKFDQLLAE----- 1517
              L++  QL     KKQ                             RK+++ + E     
Sbjct: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855

Query: 1518 --EKAAVLRAVE--------------ERERAEAEGREREARALSLTRALEEEQEAREELE 1561
              ++  VLR  +              + E A+ +      +       LEE +E  +  E
Sbjct: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915

Query: 1562 RQNRALRAELEALLSSKDDVGKSVHELE 1589
             Q   LRA+     SS+      VHE E
Sbjct: 1916 SQVNKLRAKTRDFTSSR----MVVHESE 1939


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 1288 bits (3333), Expect = 0.0
 Identities = 719/1946 (36%), Positives = 1155/1946 (59%), Gaps = 60/1946 (3%)

Query: 52   ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
            A+  V+V      F  A +  R+ G+  A+ E   +G  + +  DQ+  MNPPK+ K ED
Sbjct: 34   AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90

Query: 110  MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
            MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E
Sbjct: 91   MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150

Query: 170  VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229
             PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE  
Sbjct: 151  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210

Query: 230  VPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 289
                +     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+I
Sbjct: 211  TSGKMQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266

Query: 290  ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG- 347
            ETYLLEKSR   Q K E S+HIFYQ++      L   LL+    + Y F++ G  + P  
Sbjct: 267  ETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326

Query: 348  QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQK 407
             ++E    T  ++ +LGF+ +E +S+ ++  AV+ +GN+  K+++  +QA       A K
Sbjct: 327  DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386

Query: 408  LCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRL 467
               L  L   D  +AL  PR+KVG +YV K QT +Q   A+ ALAKA Y+++F W+V R+
Sbjct: 387  AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446

Query: 468  NRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 526
            N+ LD + PRQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY
Sbjct: 447  NQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504

Query: 527  QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-G 585
            ++EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+ ++  G
Sbjct: 505  KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561

Query: 586  GHPKFQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
                FQ+P+  +   +A FS++HYAG VDY    WL KN DPLN+ V  L  +S  +  A
Sbjct: 562  KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621

Query: 644  EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
             ++                                     G  G E  +  G G  GG+ 
Sbjct: 622  LLFV------------------------------------GATGAE--AEAGGGKKGGKK 643

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            +   F+TV  L++E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVL
Sbjct: 644  KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVL 703

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVG 822
            EGIRICR+GFP+RIL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++++D   Y+ G
Sbjct: 704  EGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFG 763

Query: 823  QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
             +K+FF+AG+L  LEE RD K+  +I   QA  RG+LAR  +QK  +++ ++  +Q N  
Sbjct: 764  HTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVR 823

Query: 883  AYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQ 942
            A++ ++HW W +L+ K+KPLL+    ++ +    +E +K +E   ++  +  EL+ ++  
Sbjct: 824  AFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVT 883

Query: 943  LEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTE 1002
            L +E+  L  Q++AEA+  A+AEE   +L   K +LE  + E+  R  +EEE + ++  +
Sbjct: 884  LMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943

Query: 1003 KKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1062
            K++L+    EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L
Sbjct: 944  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003

Query: 1063 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1122
            ++   +       EE+KV +L K ++K E  + D+E  L +E+K R +LE+ KR+L+G+ 
Sbjct: 1004 QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1063

Query: 1123 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1182
               QE  ++ +   ++L  +L +KE E+    ++ EDE     QL K ++E QA + E +
Sbjct: 1064 KLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 1123

Query: 1183 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1242
            E++E+ER +R KAEKQR DL  ELE +   LE+   +T+AQ E+  KRE E  ++++ LE
Sbjct: 1124 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183

Query: 1243 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQ 1302
            E T  HEA    LR++H  ++ EL EQ++  +R K   EK +  ++ E+ +L + + ++ 
Sbjct: 1184 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 1243

Query: 1303 TARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTI 1362
             A+   E+  R LE QL E++ +  + +R   +   +  R Q E    S  L+E ++   
Sbjct: 1244 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVS 1303

Query: 1363 RLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGR 1422
            +LS+   +   Q+ + +  L+EE +AK AL   +++   +   LREQ EEE  A+    R
Sbjct: 1304 QLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363

Query: 1423 ELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR 1481
             +  A +++++WR + E +A    E  EEA+++ A+  +   + +         LE+ ++
Sbjct: 1364 AMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQ 1423

Query: 1482 RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA 1541
            RLQ E++D  +D+E+     + L+KKQR FD++LAE K        E E ++ E R    
Sbjct: 1424 RLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLST 1483

Query: 1542 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1601
                +  A EE  +  E L+R+N+ L+ E+  L     + GK +HELE+  +  EQ  ++
Sbjct: 1484 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSE 1543

Query: 1602 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 1661
            L+A + E E  L   E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   + 
Sbjct: 1544 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQS 1603

Query: 1662 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE 1721
              D E + R  A+  +KK+EG+L E++ Q+  A +   EA++  R  QA +K+    +++
Sbjct: 1604 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDD 1663

Query: 1722 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1781
               S+E++  Q    E+R   L+AE+  L+  L  ++R+R+ A+Q+  + ++ V   +  
Sbjct: 1664 ALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1723

Query: 1782 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA 1841
              +++  K++LE  + Q++ E+E+    +    ++ +K +     +  EL  E+  SA  
Sbjct: 1724 NTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1783

Query: 1842 ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
            E  ++ LE+ +++L+ RL E +  A    K  I  LE+++ + E ++E E +  + + K 
Sbjct: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843

Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
            +R+ E+++KE+  Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   +  RR+
Sbjct: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903

Query: 1962 QRELEDVTESAESMNREVTTLRNRLR 1987
            Q ELE+  E A+    +V  LR + R
Sbjct: 1904 QHELEEAEERADIAESQVNKLRVKSR 1929



 Score =  227 bits (579), Expect = 8e-59
 Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%)

Query: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
            K+K L    LK   T  +M +   + EK ++EL K     + +  EL+E+MV   Q   +
Sbjct: 839  KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890

Query: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
            L+ Q+  + + L  A  R +       QL+K+  + +A + E  E  E E     +   +
Sbjct: 891  LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943

Query: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
            +R L +E   L+ +++D   TL     ++     + + +TE    L+E         + L
Sbjct: 944  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003

Query: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
            ++ H Q L +L  + ++         K ++ LE +V +L   L   +  R + E+ +R+L
Sbjct: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059

Query: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
            E  L+  Q    D E  + +  EKL++ + E+  +   + + ++  ++L K++   +A++
Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119

Query: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
             + +E ++ E  ++     +   +  E   + E+LEE   A        +  +A+  + R
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179

Query: 1436 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1494
            R  EE     EA     R++ A     L +++        +LE+ +  ++ E+DD   ++
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239

Query: 1495 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1550
            E   +    LEK  R  +  L+E K       EE++R   +   + AR  +     +R L
Sbjct: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295

Query: 1551 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1610
            +E+     +L R  +A   ++E L    ++  K+   L  A + +    + LR Q  E +
Sbjct: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355

Query: 1611 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1670
            +     + A  +    V   +T++E D   R E  EE +++LA++L+DAE   +    + 
Sbjct: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415

Query: 1671 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
                  +++L+ E+E+L   +           K+ R     + E  ++ EET    E   
Sbjct: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475

Query: 1731 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1790
             ++R     L  ++       ++L    R  +  QQ+  ++ +++A G      + + K+
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535

Query: 1791 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850
            Q+E    +L+  LEE +++ E    +  ++ L++  + +E+  +R  + K E   Q    
Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593

Query: 1851 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1908
             I+ +       DA  R+R+        +E  L + E QL    R    + +  R  +  
Sbjct: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653

Query: 1909 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1968
            LK+  L +++  R  + L++QL     R   L+ ++EE      + +  R+  ++EL D 
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713

Query: 1969 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
            +E  + ++ + T+L N  ++     +         ++E   ++E+A++A
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762



 Score =  189 bits (480), Expect = 2e-47
 Identities = 199/947 (21%), Positives = 418/947 (44%), Gaps = 94/947 (9%)

Query: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
            TK K  LQ   Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 997  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056

Query: 948  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
             +L   L+   E   + E  + +L  + ++ E  +S L++++ +E+    Q+Q + K LQ
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116

Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
              I+ELE  +EAE  +R K + ++     ++++  E L            + + + ++  
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176

Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
            K R+ LE+   +  + AA           E  E++ +L +++ K E         I D+ 
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236

Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
              +    K +  LEK+ R L+ + SE++ +  EQQ+   +L AQ  R + E      + +
Sbjct: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296

Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
            ++    +QL +  +     + E +  LE E  A++      +    + + LR + E+  +
Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356

Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
            +    Q   SK   EV + +   E +       ++E +++  Q L +  E +E       
Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCA 1416

Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
            + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  +   A  EA++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1475

Query: 1339 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
            K  R+   EL  +  A  E+  +   L +E  + + ++ D  E + E  +    L    +
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535

Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
             +E E + L+  LEE  A+ E    ++   Q +L++ +   + + A   E  ++ +R   
Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHI 1595

Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
            R  E++   L  +  + +   R +++++ +L++  + L    ++ +   +  R    +L 
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILK 1655

Query: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1571
            + +  +  A+  +E  + +    E RA  L   +EE +   E+ ER  +    EL     
Sbjct: 1656 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1715

Query: 1572 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1615
                      +L+++K     D+ +   E+E   + A  A    +  +T+   + +EL  
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775

Query: 1616 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1667
             +D    LE   + L+ Q  +DLQ R DEA       G+++ ++L  ++R+ E E + E+
Sbjct: 1776 EQDTSAHLERMKKNLE-QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834

Query: 1668 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1706
            K+   AV   +K E +++EL                     +A++ S  +  EEA +Q  
Sbjct: 1835 KRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894

Query: 1707 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
               ++ + +  E+EE     +   ++++ ++ R+K  E     + EE
Sbjct: 1895 VNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 1285 bits (3324), Expect = 0.0
 Identities = 726/1942 (37%), Positives = 1150/1942 (59%), Gaps = 63/1942 (3%)

Query: 57   WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
            +VP +   F  A +  R+ G+  AE E   +G+ + +  DQ+ + NPPKF K EDMA LT
Sbjct: 38   FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94

Query: 115  CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174
             L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E PPH+
Sbjct: 95   FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154

Query: 175  YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVPAS 233
            +++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+   +G+K+      
Sbjct: 155  FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDN----- 209

Query: 234  VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
             +  + G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYL
Sbjct: 210  -ANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268

Query: 294  LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
            LEKSR I Q K E ++HIFYQ+L     +L   LL+    + Y F++ G  S     + E
Sbjct: 269  LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSE 328

Query: 352  LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
                T  +  VLGF+ EE   + ++  A++ +GN+  K+++  +QA       A K   L
Sbjct: 329  ELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYL 388

Query: 412  LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
            +GL   D  + L  PR+KVG +YV K Q+ +Q  +++ ALAKA YE++F W+V R+N  L
Sbjct: 389  MGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATL 448

Query: 472  D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
            + + PRQ   F+G+LDIAGFEIF  NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 449  ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 506

Query: 531  IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
            I WTF+DFG+DLQ CIDLIE+P    G++++L+EEC FPKATD +F  K+     G    
Sbjct: 507  IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNN 563

Query: 590  FQRPRHLR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
            FQ+PR+++   +A FS++HYAG VDY    WL KN DPLN+ V AL  +S+ +L A ++ 
Sbjct: 564  FQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFS 623

Query: 648  DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
                         S+  +  G + +                           GG+ +   
Sbjct: 624  -------------SYATADTGDSGKSK-------------------------GGKKKGSS 645

Query: 708  FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 767
            F+TV  L++E+L++LM  L  T+P FVRCI+PN  K  G ++  LV+ QLRCNGVLEGIR
Sbjct: 646  FQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIR 705

Query: 768  ICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKI 826
            ICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++  EK++ +L++D N Y+ G +K+
Sbjct: 706  ICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKV 765

Query: 827  FFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLK 886
            FF+AG+L  LEE RD +++ II   QA ARG L R  F+K  +++ AL V+Q N  A++ 
Sbjct: 766  FFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG 825

Query: 887  LRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEE 946
            +++W W +L+ K+KPLL+    ++ +    +E  +++E  ++S     EL+ ++  L +E
Sbjct: 826  VKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE 885

Query: 947  RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006
            +  L  Q++AE +   +AEE   +L   K +LE  V E+  R+ +EEE + ++  +K++L
Sbjct: 886  KNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKL 945

Query: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066
            +    EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L++  
Sbjct: 946  EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1005

Query: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQ 1126
             +       EE+KV SL+K ++K E  + D+E  L +E+K R +LE+ KR+L+G+    Q
Sbjct: 1006 QQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1065

Query: 1127 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1186
            E +++ +    +L  +L +KE ++    ++ EDE     QL K L+E QA + E +E+LE
Sbjct: 1066 ESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE 1125

Query: 1187 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETR 1246
            +ER AR K EK R DL  ELE +   LE+   +T+ Q E+  KRE E  ++++ LEE T 
Sbjct: 1126 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185

Query: 1247 IHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQ 1306
             HEA    LR++H  ++ EL EQ++  +R K   EK +   + E+ ++ + +  +  A+ 
Sbjct: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245

Query: 1307 EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366
              E+  R LE Q  E + +  + +R+  +   +  + Q E   ++  L E E+   +L++
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305

Query: 1367 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQT 1426
               S   Q+ D +  L+EE +AK AL   +++   +   LREQ EEE  A+    R L  
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365

Query: 1427 AQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1485
            A +++++WR + E +A    E  EEA+++ A+  +   + +         LE+ + RLQ 
Sbjct: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425

Query: 1486 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545
            E++D  +D+E+     + L+KKQR FD++LAE K     +  E E ++ E R        
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485

Query: 1546 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1605
            L  A EE  E  E  +R+N+ L+ E+  L     + GK+VHELE+  +  E    +L++ 
Sbjct: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545

Query: 1606 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE 1665
            + E E  L   E   LR ++    +K + ER L  +DE  E+ +R   + +   +   D 
Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605

Query: 1666 ERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
            E + R   +  +KK+EG+L E++ Q++ A +   EA KQ++ +Q+ +K+   ++++   +
Sbjct: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665

Query: 1726 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1785
             +++       E+R   L+AE+  L+  +  ++R+R+ A+Q+  E ++ V   +    ++
Sbjct: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725

Query: 1786 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1845
            + +K+++E  L QL+ E+EE         ++ +K +     +  EL  E+  SA  E  +
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1785

Query: 1846 QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1905
            + +E+ I++L+ RL E +  A    K  +  LE+++ + E +LE E +    S K +R++
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKS 1845

Query: 1906 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1965
            E+R+KE+  Q EE+++   +L+D ++K  L+VK  KRQ EEAEE+A+   +  R++Q EL
Sbjct: 1846 ERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1905

Query: 1966 EDVTESAESMNREVTTLRNRLR 1987
            ++  E A+    +V  LR + R
Sbjct: 1906 DEAEERADIAESQVNKLRAKSR 1927



 Score =  236 bits (601), Expect = 2e-61
 Identities = 213/954 (22%), Positives = 431/954 (45%), Gaps = 57/954 (5%)

Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1144
            K++   ++   + E    KEE GR  +++   + +    EL+E+MV   Q   +L+ Q+ 
Sbjct: 837  KIKPLLKSAETEKEMATMKEEFGR--IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQ 894

Query: 1145 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1204
             +++ L  A  R +       QL+K+  + +A + E  E LE E     +   ++R L +
Sbjct: 895  AEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED 947

Query: 1205 ELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1261
            E   L+ +++D   TL     ++     + + +TE    L+E         + L++ H Q
Sbjct: 948  ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007

Query: 1262 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1321
            AL +L  Q+E+ +    +  K+++ LE +V +L   L   +  R + E+ +R+LE  L+ 
Sbjct: 1008 ALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063

Query: 1322 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1381
             Q    D E  + +  EKL++ + ++   +  + + +   ++L K+L   +A++ + +E 
Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEE 1123

Query: 1382 LQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE 1441
            L+ E  A+  +      +  E   + E+LEE   A        +  +A+  + RR  EE 
Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183

Query: 1442 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATMDL 1494
                EA   A R+   ++      +AE  E +D L+R +++L++E       LDD T ++
Sbjct: 1184 TLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237

Query: 1495 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQ 1554
            EQ  +  + LEK  R  +    E +  +  A         +  + +     L R LEE++
Sbjct: 1238 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1297

Query: 1555 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1614
                +L R   +   ++E L    ++ GK+ + L  A + A    + LR Q  E  +   
Sbjct: 1298 ALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKA 1357

Query: 1615 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1674
              +    +    V   +T++E D   R E  EE +++LA++L+DAE   +    + +   
Sbjct: 1358 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLE 1417

Query: 1675 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1734
              + +L+ E+E+L   +  +        K+ R     + E  ++ EE+++  E       
Sbjct: 1418 KTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES------ 1471

Query: 1735 ESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1787
             S+K  + L  E+ +L+       E L    R  +  Q++  ++ +++  G  +   + +
Sbjct: 1472 -SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530

Query: 1788 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AESG 1844
             ++QLE    +L+  LEE +++ E    +  +  L+   +  E+  ER  + K    E  
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEMEQA 1588

Query: 1845 RQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLV 1902
            ++  +R +  L+  L   DA  R+R+++      +E  L + E QL    R    + K V
Sbjct: 1589 KRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645

Query: 1903 RRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQ 1962
            +  +  LK+  +Q+++  R  D L++ +     R   L+ +LEE      + +  R+  +
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705

Query: 1963 RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
            +EL + +E  + ++ + T+L N+ ++     T    +    +EE V     AEE
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%)

Query: 918  ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 974
            +L     +  ++ ++V  LQ   + L++ + +L + +RA  +L    A  E     L A 
Sbjct: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686

Query: 975  KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 1018
             +EL  VV + E   ++ E+E  E S ++Q           +KK+++  + +L++ +E  
Sbjct: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746

Query: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1078
             +E    + + +K  T+A M    E+L   +D ++ L + +K +E  + +   +  E E+
Sbjct: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804

Query: 1079 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1137
              +K   K   K EA + ++E  L  E+K   E  K  R+ +    EL  Q  E ++   
Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864

Query: 1138 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1197
             L+  + + + +++A   +AE+        L   R+ Q  L EA+E  +       K   
Sbjct: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924

Query: 1198 QRRDLG 1203
            + RD+G
Sbjct: 1925 KSRDIG 1930


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 1276 bits (3301), Expect = 0.0
 Identities = 713/1937 (36%), Positives = 1143/1937 (59%), Gaps = 58/1937 (2%)

Query: 59   PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118
            P E +       R+ G+  A+ E   +G  + +  DQ+  MNPPK+ K EDMA +T L+E
Sbjct: 43   PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99

Query: 119  ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178
             +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E PPH+++++
Sbjct: 100  PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159

Query: 179  EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVS 238
            + AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE   PAS     
Sbjct: 160  DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEE--PASGKM-- 215

Query: 239  YGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSR 298
             G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEKSR
Sbjct: 216  QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 275

Query: 299  AIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQET 356
               Q K E S+HIFYQ+L     +L   LL+    + + F++ G  + P   ++E    T
Sbjct: 276  VTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMAT 335

Query: 357  LESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGV 416
              ++ +LGF+ +E +++ ++  AV+ +GN+  K+++  +QA       A K   L  L  
Sbjct: 336  DSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNS 395

Query: 417  TDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSP 475
             D  ++L  PR+KVG ++V K QT +Q   A+ ALAKA YE++F W+V R+N+ LD + P
Sbjct: 396  ADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQP 455

Query: 476  RQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTF 535
            RQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F
Sbjct: 456  RQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEF 513

Query: 536  LDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPR 594
            +DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+ ++  G    FQ+P+
Sbjct: 514  IDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPK 570

Query: 595  HLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGG 652
              +   +A FS++HYAG VDY    WL KN DPLN+ V  L  +S  +  A         
Sbjct: 571  PAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA--------- 621

Query: 653  FQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVG 712
               F F G+      G                          G G  GG+ +   F+TV 
Sbjct: 622  ---FLFSGAQTAEAEG--------------------------GGGKKGGKKKGSSFQTVS 652

Query: 713  QLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQG 772
             L++E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEGIRICR+G
Sbjct: 653  ALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKG 712

Query: 773  FPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAG 831
            FP+RIL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++E+D   Y+ G +K+FF+AG
Sbjct: 713  FPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAG 772

Query: 832  VLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQ 891
            +L  LEE RD K+  +I   QA  RG+L R  F+K  +++ ++  +Q N  A++ ++HW 
Sbjct: 773  LLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWP 832

Query: 892  WWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLA 951
            W +L+ K+KPLL+    ++ +    +E +K +E   ++  +  EL+ ++  L +E+  L 
Sbjct: 833  WMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQ 892

Query: 952  EQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQ 1011
             Q++AEA+  A+AEE   +L   K +LE  + E+  R  +EEE + ++  +K++L+    
Sbjct: 893  LQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 952

Query: 1012 ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSS 1071
            EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L++   +   
Sbjct: 953  ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012

Query: 1072 QAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVE 1131
                EE+KV +L K + K E  + D+E  L +E+K   +LE+ KR+L+G+    QE  ++
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072

Query: 1132 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
             +   ++L  +L +KE E+     + EDE     QL K ++E QA + E +E++E+ER +
Sbjct: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERAS 1132

Query: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
            R KAEKQR DL  ELE +   LE+   +T+AQ E+  KRE E  ++++ LEE T  HEA 
Sbjct: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEAT 1192

Query: 1252 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1311
               LR++H  ++ EL EQ++  +R K   EK +  L+ E+++L + + ++  A+   E+ 
Sbjct: 1193 AAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKM 1252

Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
             R LE QL E++ +  + +R   E + +  R   E    S  L+E ++   +LS+   + 
Sbjct: 1253 CRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAF 1312

Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1431
              Q+ + +  L+EET+AK  L   +++   +   LREQ EEE  A+    R +  A +++
Sbjct: 1313 TQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEV 1372

Query: 1432 SEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDA 1490
            ++WR + E +A    E  EEA+++ A+  +   + +         LE+ ++RLQ E++D 
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDL 1432

Query: 1491 TMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRAL 1550
             +D+E+       L+KKQR FD++LAE K        E E ++ E R        +  A 
Sbjct: 1433 MIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAY 1492

Query: 1551 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1610
            EE  +  E L+R+N+ L+ E+  L     + GK +HELE+  +  +   ++L+  + E E
Sbjct: 1493 EESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAE 1552

Query: 1611 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1670
              L   E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   +   D E + R
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSR 1612

Query: 1671 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
              A+  +KK+EG+L E++ Q+  A +   EA++ LR  Q  +K+    +++    ++++ 
Sbjct: 1613 NDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLK 1672

Query: 1731 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1790
             Q    E+R   ++AEV  L+  L  ++R R+ A+Q+  + ++ V   +    +++  K+
Sbjct: 1673 EQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKK 1732

Query: 1791 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850
            +LE  + Q++ E+E+    +    ++ +K +     +  EL  E+  SA  E  ++ +E+
Sbjct: 1733 KLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1792

Query: 1851 QIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 1910
             +++L+ RL E +  A    K  I  LE+++ + E ++E E +  + + K +R+ E+R+K
Sbjct: 1793 TVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVK 1852

Query: 1911 EVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTE 1970
            E+  Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   A  R+LQ ELE+  E
Sbjct: 1853 ELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKE 1912

Query: 1971 SAESMNREVTTLRNRLR 1987
             A+    +V  LR + R
Sbjct: 1913 RADIAESQVNKLRVKSR 1929



 Score =  241 bits (615), Expect = 5e-63
 Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%)

Query: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
            K+K L    LK   T  +M +   + EK ++EL K     + +  EL+E+MV   Q   +
Sbjct: 839  KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890

Query: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
            L+ Q+  + + L  A  R +       QL+K+  + +A + E  E  E E     +   +
Sbjct: 891  LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943

Query: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
            +R L +E   L+ +++D   TL     ++     + + +TE    L+E         + L
Sbjct: 944  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003

Query: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
            ++ H Q L +L  Q+E+ +       KT+L  E +V +L   L   +    + E+ +R+L
Sbjct: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059

Query: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
            E  L+  Q    D E  + +  EKL++ + E+ N+ G + + ++  I+L K++   +A++
Sbjct: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119

Query: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
             + +E ++ E  ++     +   +  E   + E+LEE   A        +  +A+  + R
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179

Query: 1436 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1495
            R  EE     EA   A R+   ++      +AE  E +D L+R +++L++E  +  M++ 
Sbjct: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233

Query: 1496 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1548
                 + T+ K +  F+++   L ++ + +    EE++R   E   ++AR  +     +R
Sbjct: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293

Query: 1549 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
             L+E+     +L R  +A   ++E L    ++  K+   L  A + A    + LR Q  E
Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353

Query: 1609 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1668
             ++     +    +    V   +T++E D   R E  EE +++LA++L+DAE   +    
Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413

Query: 1669 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1728
            +       +++L+ E+E+L   +  +        K+ R     + E  ++ EET+   E 
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473

Query: 1729 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1788
               ++R     L  ++       + L    R  +  QQ+  ++ +++A G      + + 
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533

Query: 1789 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1848
            K+QL+    +L+  LEE +++ E    +  ++ L++  + +E+  +R  + K E   Q  
Sbjct: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591

Query: 1849 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1906
               ++ +       DA  R+R+        +E  L + E QL    R+   + + +R  +
Sbjct: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651

Query: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1966
              LK+  L +++  R  D L++QL     R   ++ ++EE      R + GR+  ++EL 
Sbjct: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711

Query: 1967 DVTESAESMNREVTTLRNRLRR 1988
            D +E  + ++ + T+L N  ++
Sbjct: 1712 DASERVQLLHTQNTSLINTKKK 1733



 Score =  181 bits (458), Expect = 8e-45
 Identities = 204/949 (21%), Positives = 411/949 (43%), Gaps = 98/949 (10%)

Query: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
            TK K  LQ   Q  +  LQ    ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 997  TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056

Query: 948  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
             +L   L+   E   + E  + +L  + ++ E  +S L+ ++ +E+  + Q+Q + K LQ
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116

Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
              I+ELE  +EAE  +R K + ++     ++++  E L            + + + ++  
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176

Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
            K R+ LE+   +  + AA           E  E++ SL +++ K E         I D+ 
Sbjct: 1177 KMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLA 1236

Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
              +    K +   EK+ R L+ + SE++ +  EQQ+   EL AQ  R   E      + +
Sbjct: 1237 SNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLD 1296

Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
            ++    +QL +  +     + E +  LE E  A++      +    + + LR + E+  +
Sbjct: 1297 EKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQE 1356

Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
            +    Q   SK   EV + +   E +       ++E +++  Q L +  E +E       
Sbjct: 1357 AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCA 1416

Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
            + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  + + A  EA++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQ-AELEASQ 1475

Query: 1339 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
            K  R+   EL  V  A  E+      L +E  + + ++ D  E + E  +    L    +
Sbjct: 1476 KESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK 1535

Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
             ++ E + L+  LEE  A+ E    ++   Q +L++ +   + + A   E  ++ +R   
Sbjct: 1536 QLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHL 1595

Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL--------EQQRQLVST----- 1503
            R  E++   L  +  + +   R +++++ +L++  + L        E  R L +T     
Sbjct: 1596 RVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILK 1655

Query: 1504 -----LEKKQRKFDQL-----LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1553
                 L+   R  D L     + E +A +++A  E  RA  E  ER  +     + L + 
Sbjct: 1656 DTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE--QELLDA 1713

Query: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613
             E  + L  QN +L    + L +    +   + ++ +  R AE+ A         + +EL
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773

Query: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDE 1665
               +D    LE   + ++ Q  +DLQ R DEA       G+++ ++L  ++R+ E E + 
Sbjct: 1774 KKEQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVES 1832

Query: 1666 ERKQRTLAVAARKKLEGELEELKAQ---------------------MASAGQGKEEAVKQ 1704
            E+K    AV   +K E  ++EL  Q                     + +  +  EEA +Q
Sbjct: 1833 EQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQ 1892

Query: 1705 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
                 A+ ++L  E+EE +   +   ++++ ++ R+K  E     + EE
Sbjct: 1893 SNVNLAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939



 Score =  135 bits (340), Expect = 4e-31
 Identities = 170/785 (21%), Positives = 329/785 (41%), Gaps = 120/785 (15%)

Query: 1288 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAEL 1347
            E E++ ++ E    +    + E +R+ LE ++  +     D               Q ++
Sbjct: 850  EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKND--------------LQLQV 895

Query: 1348 ENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLR 1407
            +  + AL +AE +  +L K     EA++ +  E  ++E      L ++ R +E E + L+
Sbjct: 896  QAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955

Query: 1408 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE--AGEEARRRAAREAEALT-Q 1464
            + +++      +  +E    + ++   +   EE AG  E  A     ++A +EA   T  
Sbjct: 956  KDIDDLELTLAKVEKEKHATENKV---KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012

Query: 1465 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1524
             L  + + V+ L + + +L+Q++DD    LEQ+++L   LE+ +RK +  L   + + + 
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072

Query: 1525 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1584
               ++++   + +++E    +L   +E+EQ    +L+++ + L+A +E L   ++++   
Sbjct: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEEL---EEEI--- 1126

Query: 1585 VHELERACRV-AEQAANDLRAQVTELEDELT---AAEDAKLRLEVTVQALKTQHERDLQG 1640
              E ERA R  AE+  +DL  ++ E+ + L     A  A++ +    +A   +  RDL+ 
Sbjct: 1127 --EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184

Query: 1641 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1700
                 E     L K+  D+  E  E   Q       ++KLE E  ELK ++       E 
Sbjct: 1185 STLQHEATAAALRKKHADSVAELGE---QIDSLQRVKQKLEKEKSELKMEINDLASNMET 1241

Query: 1701 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1760
              K     +   + L  ++ E +T  EE        ++ +  L A+  RL  E   S   
Sbjct: 1242 VSKAKANFEKMCRTLEDQLSEIKTKEEE-------QQRLINELSAQKARLHTE---SGEF 1291

Query: 1761 RRQAQQDRDEMADEVANGNLSKAAILEE-KRQLEGRLGQ-----------------LEEE 1802
             RQ  + +D M  +++ G  +    +EE KRQLE                      L E+
Sbjct: 1292 SRQLDE-KDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQ 1350

Query: 1803 LEEEQ------------SNSEL-----------------LNDRYRKLLLQVESLTTELSA 1833
             EEEQ            +NSE+                 L +  +KL  +++     + A
Sbjct: 1351 YEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1410

Query: 1834 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKM------TIAALESKLAQAEEQ 1887
              S  A  E  +Q+L+ ++++L   +   +A   A  K        +A  + K  + + +
Sbjct: 1411 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE 1470

Query: 1888 LEQETRE-RILSGKL----------------VRRAEKRLKEVVLQVEEERRVADQLRDQL 1930
            LE   +E R LS +L                ++R  K L++ +  + E+     +   +L
Sbjct: 1471 LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHEL 1530

Query: 1931 EKGNLRV----KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
            EK   ++     +L+  LEEAE      +    R+Q EL  V    +    E     ++L
Sbjct: 1531 EKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQL 1590

Query: 1987 RRGPL 1991
            +R  L
Sbjct: 1591 KRNHL 1595


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 1245 bits (3221), Expect = 0.0
 Identities = 712/1920 (37%), Positives = 1118/1920 (58%), Gaps = 77/1920 (4%)

Query: 87   RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146
            R L L  DQ+  MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N
Sbjct: 68   RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127

Query: 147  PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206
            PYK LP+Y   +V  YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT 
Sbjct: 128  PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187

Query: 207  NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266
            NTK+VIQY A +A +   +KE   P  +     G LE Q++QANP+LEAFGNAKTV+NDN
Sbjct: 188  NTKRVIQYFATIAVTGDKKKETQ-PGKMQ----GTLEDQIIQANPLLEAFGNAKTVRNDN 242

Query: 267  SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326
            SSRFGKFIRI+F   G +  A+IETYLLEKSR   Q   E S+HIFYQ++     +L  D
Sbjct: 243  SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-ID 301

Query: 327  LLLEPCSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSA 379
            LLL   + + F    P  S G+       + E    T  ++ +LGFS EE + + ++  A
Sbjct: 302  LLLISTNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGA 357

Query: 380  VLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQ 439
            V+ +GN+  K+++  +QA       A K   L+GL   +  + L  PR+KVG +YV K Q
Sbjct: 358  VMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQ 417

Query: 440  TKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSF 498
              +Q   ++ ALAKA YE++F W+V R+N+ LD + PRQ   F+G+LDIAGFEIF  NS 
Sbjct: 418  NVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSL 475

Query: 499  EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGL 558
            EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL  CI+LIE+P    G+
Sbjct: 476  EQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GI 532

Query: 559  LALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKA 615
             ++L+EEC FPKATD SF  K+  Q  G    FQ+P+  + +A+  FS++HYAG VDY  
Sbjct: 533  FSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNI 592

Query: 616  NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSS 675
              WL KN DPLN+ V  L  +S+ +L + ++ +  G                        
Sbjct: 593  AGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----------------------- 629

Query: 676  AISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 735
                          +    G    GG+ +   F+TV  +++E+L++LM  L +T+P FVR
Sbjct: 630  --------------ETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVR 675

Query: 736  CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 795
            C++PN  K  G ++  LV+ QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY IL  +AIP
Sbjct: 676  CLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIP 735

Query: 796  KG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAA 854
            +G F+D K A EK++ ++++D   +R G +K+FF+AG+L  LEE RD K+  ++ S QA 
Sbjct: 736  EGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAV 795

Query: 855  ARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQA 914
             RGYL R  F+K  +++ ++  +Q N  +++ ++HW W  LF K+KPLL+    ++ +  
Sbjct: 796  CRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMAT 855

Query: 915  RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAAR 974
              ++ ++ +E   +S     EL+ ++  L +E+  L  Q+++E E   +AEE    L   
Sbjct: 856  MKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKS 915

Query: 975  KQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTT 1034
            K  LE  V EL  R+ EEEE + ++  +K+ L+     L+  ++  E    K++ EK  T
Sbjct: 916  KILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHAT 975

Query: 1035 EAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI 1094
            E K+K   E++  LE+  SKL+KE+K L++   +       EE+KV  L K+  K E   
Sbjct: 976  ENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQT 1035

Query: 1095 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1154
             D+E  L +E+K R +LE+ KR+L+G+    QE +++ +   +++  +L +KE EL    
Sbjct: 1036 DDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQ 1095

Query: 1155 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1214
            A+ +DE     Q  K ++E QA + E +E++E+E   R K EKQR DL  ELE +   LE
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155

Query: 1215 DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQAR 1274
            +   +T+AQ E+  KRE E  ++++ LEE T  HEA    LR++   ++ EL EQ++  +
Sbjct: 1156 EASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQ 1215

Query: 1275 RGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 1334
            R K   EK +  L+ E+ ++ + + +L  ++   E+  R +E Q  E+  +A D ++ + 
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI--KAKDEQQTQL 1273

Query: 1335 EAAEKLQRAQAELEN--VSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLAL 1392
                 +Q+A+ + +N  +S  + E ES   +L+K   +   QL + +  ++EET+AK A+
Sbjct: 1274 IHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333

Query: 1393 GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEA 1451
               +++   +   LREQ EEE  A+    R L  A +++++WR + E +A    E  EEA
Sbjct: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1393

Query: 1452 RRRAAREAEALTQRLAEKTETVD----RLERGRRRLQQELDDATMDLEQQRQLVSTLEKK 1507
            +++ A+      Q   E TET +     LE+ ++RLQ E++D   DLE+     +TL+KK
Sbjct: 1394 KKKLAQR----LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKK 1449

Query: 1508 QRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL 1567
            QR FD++LAE K  +  +  E E A+ E R        +  A EE  +  E L R+N+ L
Sbjct: 1450 QRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNL 1509

Query: 1568 RAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV 1627
            + E+  L     + GK++ E E+  ++ EQ  +DL+  + E+E  L   E   LR+++ +
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569

Query: 1628 QALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEEL 1687
              +K++ +R +  +DE  E+ +R   +     +   D E + R  A+  +KK+EG+L E+
Sbjct: 1570 SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEM 1629

Query: 1688 KAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEV 1747
            + Q+  + +   E  K LR +Q Q+K+    +++   S E++  Q    E+R   L  E+
Sbjct: 1630 EIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEEL 1689

Query: 1748 LRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
              ++  L  ++R RR ++Q+  + +D V   +    +++  K++LE  + Q + E+E   
Sbjct: 1690 EEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSI 1749

Query: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
              S    ++ +K +     +  EL  E+  SA  E  ++ LE+ +++L+ RL E +  A 
Sbjct: 1750 QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809

Query: 1868 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLR 1927
               K  I  LE+++ + E +L+ E +    + K   + E+++KE+  Q EE+ +   +L+
Sbjct: 1810 KGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQ 1869

Query: 1928 DQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
            D ++K   +VK  KRQ EEAEE+A+   +  RR+Q ELE+  E A+    +V  LR + R
Sbjct: 1870 DLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929



 Score =  214 bits (546), Expect = 5e-55
 Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%)

Query: 1085 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142
            K++   ++  A+ E    KE  E+ ++EL + + R      EL+E+MV   Q   +L+ Q
Sbjct: 839  KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894

Query: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202
            +  + E L  A  R E        L+KS    +A + E  E LE E    ++   ++R+L
Sbjct: 895  VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947

Query: 1203 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1259
             ++  +L+ +++D   TL     ++     + + ++E    LEE         + L++ H
Sbjct: 948  EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007

Query: 1260 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1319
             Q L +L  Q+E+ +       K    LE +  +L   L   +  R + E+ +R+LE  L
Sbjct: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063

Query: 1320 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1379
            +  Q    D E  + +  EKL++ + EL  +   +++ +  +++  K++   +A++ + +
Sbjct: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123

Query: 1380 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1439
            E ++ E   +  +  +   +  E   + E+LEE + A        +  +A+  + RR  E
Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183

Query: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499
            E     EA     R+   ++      +AE  E +D L+R +++L++E  +  M+++    
Sbjct: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237

Query: 1500 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1552
             +  L K +   ++     E++ + ++A +E++         +   L      L+  +EE
Sbjct: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297

Query: 1553 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1612
            ++    +L +  +AL  +LE L    ++  K+ + +  A + +    + LR Q  E ++ 
Sbjct: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357

Query: 1613 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1672
                + A  +    V   +T++E D   R E  EE +++LA++L++AE   +    +   
Sbjct: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417

Query: 1673 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1732
                +++L+GE+E+L   +  +        K+ R     + E  ++++E++   E    +
Sbjct: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477

Query: 1733 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1792
            +R     L  +      + ++L    R  +  Q++  ++ +++A    +     + K+ +
Sbjct: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537

Query: 1793 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1852
            E     L+  LEE + + E    +  ++ L++  + +EL  +R    K E   +QL+R  
Sbjct: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594

Query: 1853 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1909
            Q     L    DA  R+R+        +E  L + E QL    R+   + K +R  + +L
Sbjct: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654

Query: 1910 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1969
            K+  L +++  R  + L++QL     R   L  +LEE +    + +  RR  ++EL D +
Sbjct: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714

Query: 1970 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
            +  + ++ + T+L N  ++               ++E   ++E+A++A
Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762



 Score =  139 bits (349), Expect = 4e-32
 Identities = 181/852 (21%), Positives = 343/852 (40%), Gaps = 195/852 (22%)

Query: 912  LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL 971
            LQA+  + ++V  LQ Q  +++ ELQ R+ +LEEE       + AE  L A+ E+ R  L
Sbjct: 1094 LQAKIDD-EQVHSLQFQ--KKIKELQARIEELEEE-------IEAEHTLRAKIEKQRSDL 1143

Query: 972  AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE----------- 1020
            A   +E+   + E       + E +++ + E +++++ ++E     EA            
Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADS 1203

Query: 1021 -----------EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1069
                       +  +QKL+ EK   + ++     ++  L    S + +  + +ED+ +E 
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI 1263

Query: 1070 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1129
             ++  ++ + +  LN  + + +    ++  R+ ++E    +L K K+ L  +  EL+ QM
Sbjct: 1264 KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM 1323

Query: 1130 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESER 1189
             E+ +    +   L     +      + E+E  A+A+L ++L +A + +A+ +   E++ 
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDA 1383

Query: 1190 VARTKA-EKQRRDLGEELEA---------------------LRGELEDTLD----STNAQ 1223
            + RT+  E+ ++ L + L+                      L+GE+ED +     S  A 
Sbjct: 1384 IQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTAC 1443

Query: 1224 QELRSKR---EQEVTELKKTLEEETRIHEAAVQELRQ------RHGQALGELAEQLEQAR 1274
              L  K+   ++ + E K+ L+E     EAA +E R       +   A  E+ +QLE  R
Sbjct: 1444 ATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLR 1503

Query: 1275 R-------------------GKGAWE--KTRLALEAEVSELRAELSSLQTARQEGEQRRR 1313
            R                   GK   E  KT+  +E E S+L+  L  ++ + +  E +  
Sbjct: 1504 RENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKIL 1563

Query: 1314 RLELQLQEVQGRAGDGERARAEAAEKL----QRAQAELENV------------------S 1351
            R++L+L +V+         + E  E+L    QRA   L++V                   
Sbjct: 1564 RVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKME 1623

Query: 1352 GALNEAE-------SKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
            G LNE E        +     K L + + QL D+Q  L +  R+   L  ++  +E    
Sbjct: 1624 GDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNG 1683

Query: 1405 GLREQLEEEAAARERAGRELQTAQAQLSE-----------------WRRRQEEEAGALEA 1447
             L E+LEE   A E+  R  + ++ +L +                  +++ E +    +A
Sbjct: 1684 LLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA 1743

Query: 1448 -----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 1496
                        EE  ++A  +A  + + L ++ +T   LER ++ L+Q + D    L++
Sbjct: 1744 EVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803

Query: 1497 QRQL--------VSTLEKKQRKFDQLL---------------------------AEE--- 1518
              QL        +  LE + R+ +  L                           AEE   
Sbjct: 1804 AEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHK 1863

Query: 1519 ------------KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRA 1566
                        +A V     + E AE +   + +R   +   LEE  E  +  E Q   
Sbjct: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNK 1923

Query: 1567 LRAELEALLSSK 1578
            LRA+   + S K
Sbjct: 1924 LRAKSRDVGSQK 1935



 Score =  116 bits (291), Expect = 2e-25
 Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%)

Query: 894  RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 943
            R+  K   + Q+T+  + L  + +EL++  E +           QS+R   +L     Q 
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351

Query: 944  EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 997
            EEE+   AE  RA ++  +E  + R +       R +ELE    +L  R+ E EE +   
Sbjct: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411

Query: 998  -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1047
                  ++  K+RLQ  +++L   LE    A     +++   +KV  E K K  E    L
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471

Query: 1048 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1107
               Q     KE + L   L +  +   E  +++++L +     +  I+D+ +++ +  K 
Sbjct: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526

Query: 1108 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1167
             QE EK K+ ++ E S+LQ  + E +   E   +++ R + EL    +  + +   + + 
Sbjct: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586

Query: 1168 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1227
            ++ L+      AEA   L+S   A  ++      L +++E    E+E  L  +N Q    
Sbjct: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643

Query: 1228 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1281
             K  + V  +LK +   L++  R +E   ++L   +R     G L E+LE+ +      E
Sbjct: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700

Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
            +TR   E E+ +    +  L +        +++LE  + + Q    +  +    A EK +
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760

Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1400
            +A  +   ++  L + +  +  L +   + E  + D Q  L E  +  L  G + ++ +E
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820

Query: 1401 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1460
                 L  +L+ E      A +     + ++ E   + EE+   +   ++   +   + +
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880

Query: 1461 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518
            +  ++  E  E  +      RR+Q EL++A    +     V+ L  K R       EE
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 1141 bits (2952), Expect = 0.0
 Identities = 681/1947 (34%), Positives = 1081/1947 (55%), Gaps = 72/1947 (3%)

Query: 53   RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112
            ++  W+P   + +  A ++   ++   +     G  L +  D+IQ+MNPP+F   EDMA 
Sbjct: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110

Query: 113  LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172
            LT LNEASVLH L+ RY   +IYTYSGLFCV INPYK LP+Y + ++  Y+GK+R E PP
Sbjct: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170

Query: 173  HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA 232
            H++AV   A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + RK+ G   
Sbjct: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228

Query: 233  SVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 292
                     LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ Y
Sbjct: 229  ---------LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIY 279

Query: 293  LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERE 351
            LLEKSR I Q   E ++HIFYQ+L G  E     L+    S + F + G  +     + E
Sbjct: 280  LLEKSRVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAE 339

Query: 352  LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
                T +++ +LGF  +E     ++  A++ FGN+  K++   +Q        A K   L
Sbjct: 340  ELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFL 399

Query: 412  LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
            +G+  ++  + L+ PRIKVG +YV + QT EQ   A+ AL+K+ YER+F+WLV R+NRAL
Sbjct: 400  MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459

Query: 472  D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
            D +  RQ   F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN  MFVLEQEEY++E 
Sbjct: 460  DAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKES 517

Query: 531  IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---H 587
            I W  + FGLDLQ CIDLIE+P    G+L++L+EEC FPKATD +F  K+     G   H
Sbjct: 518  IEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVH 574

Query: 588  PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
             +  +P   + +A F ++HYAG V Y  + WL KN D LN+ V A+  +S++RL A +++
Sbjct: 575  LQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFE 634

Query: 648  DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
            +         ++ +    P G  +R   A                               
Sbjct: 635  N---------YMSTDSAIPFGEKKRKKGA------------------------------S 655

Query: 708  FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 767
            F+TV  L+KE+L++LM  L +T P FVRCI PN  K  G L+P LVL QLRCNGVLEG R
Sbjct: 656  FQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTR 715

Query: 768  ICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKI 826
            ICR+GFPNR+ + +F+QRY IL P   PK  F+  ++A E+++ +LE+D   YR G +K+
Sbjct: 716  ICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKV 775

Query: 827  FFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLK 886
            FF+AG L QLE  RD +++ +   FQA A+G L R  FQK  +++ AL ++Q N  A++ 
Sbjct: 776  FFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMA 835

Query: 887  LRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEE 946
            +++W W RLF K+KPL++ +   E +    +E  ++Q+  ++S  +  EL+ +   L +E
Sbjct: 836  VKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQE 895

Query: 947  RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006
            +  L  QL+AE E  A  EE    L   K +LE  V EL  RV EEEE + ++    ++L
Sbjct: 896  KNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKL 955

Query: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066
            +    EL+  ++  E    K + EK TTE K+K   E++  L +  SKL++  K++++  
Sbjct: 956  EDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAH 1015

Query: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQ 1126
             +       EEEK+ SL+K  LK E  + ++E  L +E K R   E+   +L+G     +
Sbjct: 1016 QQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNR 1075

Query: 1127 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1186
            E M   +     L  +L +KE EL    ++ E+E G  AQL K+++E Q  + + +E LE
Sbjct: 1076 ESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLE 1135

Query: 1187 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETR 1246
            +ER  R K E++R DL ++L  L   LE+   S+ AQ E+  K+E +  +L + +EE T 
Sbjct: 1136 AERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATL 1195

Query: 1247 IHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQ 1306
              E     L++RH  +L EL  Q+E  ++ K   EK +  L+ EV +L   +  +  A+ 
Sbjct: 1196 HFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKA 1255

Query: 1307 EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366
              E+     E +L E   +     +   + A +  +  +E       L E E+   +LS+
Sbjct: 1256 NAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR 1315

Query: 1367 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQT 1426
            E S+   Q+ D +  L++ET+++ AL   ++  + +   LREQ EEE   +    R L  
Sbjct: 1316 EKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSK 1375

Query: 1427 AQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1485
              A++ +WR + E       E  E+A++  A   +   + +         LER R +LQ 
Sbjct: 1376 VNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435

Query: 1486 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545
            EL DA  DL + R   + L++KQ +  + LA+ K        E  +A  +  ++E +ALS
Sbjct: 1436 ELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQK-----HEESQALLDASQKEVQALS 1490

Query: 1546 -----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1600
                 L    EE    +E L R+N+ L+ E+  L +   +  K++ E+E+  ++ E+   
Sbjct: 1491 TELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKT 1550

Query: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660
            +++  + E E  L   E   L  ++ +   K + ER L  +DE  E  RR+    +   +
Sbjct: 1551 EVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQ 1610

Query: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720
               D E K R      +KK+E +L E++ Q++ A +   EA K L ++Q Q+K+L  +++
Sbjct: 1611 SSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLD 1670

Query: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780
            ++     ++  Q   +E+R   L++E+  L+     ++R RR ++++  E  + +     
Sbjct: 1671 DSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYT 1730

Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840
               ++L +K++LE  + ++++E EE     +   ++ +K  ++  +L+ EL  ++   A 
Sbjct: 1731 QNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAH 1790

Query: 1841 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGK 1900
             E  R+ +E+ I +L+ RL E +  A    +  I  LES++ + E +LE E R    + +
Sbjct: 1791 LERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQR 1850

Query: 1901 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1960
              RR E+ +KE+  Q EE+++   +++ Q++K  L+V+  K+Q+E AE +A++  +  ++
Sbjct: 1851 GARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKK 1910

Query: 1961 LQRELEDVTESAESMNREVTTLRNRLR 1987
             Q EL +V E AE    +V  L+ + R
Sbjct: 1911 QQHELNEVKERAEVAESQVNKLKIKAR 1937



 Score =  189 bits (479), Expect = 3e-47
 Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%)

Query: 1028 QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1084
            QLE +  E   K F    L       KL   K +K+LE+R A    Q        VK+  
Sbjct: 784  QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840

Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
             +RL ++         + +E  G +E    L+K   + + +  EL+ + V   Q   +L 
Sbjct: 841  WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900

Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
             QL  ++E L     + E        L+KS  + +A + E  E +E E    ++   + R
Sbjct: 901  LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953

Query: 1201 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257
             L +E   L+ E++D    L  +  ++     + + +TE  + L E+      A + +++
Sbjct: 954  KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013

Query: 1258 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1317
             H Q L +L  + E+      +  K  L LE +V EL   L   + AR   E+   +LE 
Sbjct: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069

Query: 1318 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1377
             L+  +    + E ++   AE+L++ + EL  ++  +   +    +L K +   + Q+ D
Sbjct: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129

Query: 1378 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1434
             +E L+ E  TRAK+    R RA +  + A L E+LEE   +        +  + +  + 
Sbjct: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186

Query: 1435 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1493
             R  EE     E    + ++   ++ A  +   E  + V  +LE+ +  LQ E+DD    
Sbjct: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246

Query: 1494 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1553
            +EQ  +  +  EK    +++ L E  A + +  +      A+  +  + +    R LEE+
Sbjct: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306

Query: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613
            +    +L R+      ++E L    +   KS   L  A + A++  + LR Q  E ++  
Sbjct: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366

Query: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
                    ++   +   + ++E ++  R E  E+ +++LA +L++A         +    
Sbjct: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426

Query: 1674 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1733
              AR +L+ EL +  + +         A  +L + Q Q     + + + +   EE  +  
Sbjct: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479

Query: 1734 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1786
              S+K ++ L  E+L+L    +E +   +  RR+    Q++   + ++V  G  +   + 
Sbjct: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539

Query: 1787 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1843
            + K+ +E    +++  LEE +   E   +  + L  Q+E L  +   ER  S K    E+
Sbjct: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597

Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1901
             R++ +  I  L+  L   D+ A++R ++T     +E  L + E QL    R+   + K 
Sbjct: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654

Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
            + + + ++K++ +Q+++  ++   L++Q+     R   L+ +LE+      + + GRR  
Sbjct: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714

Query: 1962 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
            + EL + TE       + T+L ++ ++          R     EE V   + AEE
Sbjct: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  554 bits (1427), Expect = e-157
 Identities = 458/1542 (29%), Positives = 738/1542 (47%), Gaps = 170/1542 (11%)

Query: 56   VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106
            VW+P     + +A L     EG++  ++ L E    L  P D +QR       NP     
Sbjct: 13   VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70

Query: 107  AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165
              D+  L+ L+E +VLHNL+ R+  S  IYTY G+  V INPY+QLPIY + ++  Y G+
Sbjct: 71   ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130

Query: 166  KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225
               ++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K  ++Y A V  S    
Sbjct: 131  NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---- 186

Query: 226  KEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIV 285
                        S   +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD   +I+
Sbjct: 187  -----------ASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHII 235

Query: 286  GANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS 345
            GAN+ TYLLEKSR + QA DE ++HIFYQL   AG     +L L     + + + G  +S
Sbjct: 236  GANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTS 295

Query: 346  --PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDN 402
                 + E F++T ++  +LG      +S+ ++++++L  G++A++ ER+ D  ++ P +
Sbjct: 296  IEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQD 355

Query: 403  TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 462
                  CRLLG+  +     L   ++    +   K  + +Q   A  ALAK  Y +LF W
Sbjct: 356  VYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGW 415

Query: 463  LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 522
            +V  +N+AL  S +Q  SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LE
Sbjct: 416  IVEHINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474

Query: 523  QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 582
            QEEY +E IPWT +DF  D QPCIDLIE      G+L LLDEEC  PK TD+++ +K+  
Sbjct: 475  QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYD 530

Query: 583  EQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 642
                   FQ+PR       F ++H+A KV+Y ++ +L KN D + +    +L  S   L 
Sbjct: 531  RHSSSQHFQKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588

Query: 643  AEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGR 702
            A+++ D+             P + PG     SS IS                   PP   
Sbjct: 589  ADLFHDDK---------DPVPATTPGKGS--SSKISVRSAR--------------PPMKV 623

Query: 703  PRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGV 762
              +   +TVG  ++ SL  LM TL+ T P +VRCI PN EK     +P+  + QLR  GV
Sbjct: 624  SNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGV 683

Query: 763  LEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVG 822
            LE IRI   G+P+R  + +F  RY +L          D K  C  +++ L  DP+ ++ G
Sbjct: 684  LETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELANTDKKAICRSVLENLIKDPDKFQFG 742

Query: 823  QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
            ++KIFFRAG +A LE+ R  K     +  Q   RG+L +    K  + + A   +QR C 
Sbjct: 743  RTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK---VKYHRLKGATLTLQRYCR 799

Query: 883  AYLKLR-------------HWQWWRLFTKVKPLLQVTRQDEVLQA--RAQELQKV--QEL 925
             +L  R               + +R+    +   +V R   V+QA  RA  +++   Q L
Sbjct: 800  GHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVL 859

Query: 926  QQQSAREVGE-LQGRVAQLEEERARLA--------EQLRAEAELCAEAEETRG--RLAAR 974
             +  A  + + ++G +A+   +R R A          L+A  EL A   E R    L   
Sbjct: 860  MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRL 919

Query: 975  KQELELVVSELEARVGEEEE----CSRQMQTEKKRLQQHIQELEAHL-----EAEEGARQ 1025
               +E  V +L+ ++ E+ +     S Q+          ++ L+  L        E    
Sbjct: 920  NVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSL 979

Query: 1026 KLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
            +LQ E  +   ++++   +  +LED +   S+E+  L  R+A+   + A  +++ + LN 
Sbjct: 980  RLQEEVESLRTELQRAHSERKILEDAH---SREKDELRKRVADLEQENALLKDEKEQLNN 1036

Query: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQL-- 1143
              L       +      KE   ++ELE+ + R       L ++  + +QR + LR ++  
Sbjct: 1037 QILCQSKD--EFAQNSVKENLMKKELEEERSRY----QNLVKEYSQLEQRYDNLRDEMTI 1090

Query: 1144 ------GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE-DLESERVART--- 1193
                   R+    Q++L   E +    +     + + + AL + +E  LE   +  T   
Sbjct: 1091 IKQTPGHRRNPSNQSSL---ESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFL 1147

Query: 1194 KAEKQRRDLGEELEALRGELE--DTLDSTNAQQE-------LRSKREQEVTELKK-TLEE 1243
            K +K+ R+L +E + L+ +LE  +  DS   Q E       L    +     LK+  LE 
Sbjct: 1148 KLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELES 1207

Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
            E +  +  + ELR+        +A+Q  Q     G+ +   L            L+ L+ 
Sbjct: 1208 ENKKLKNDLNELRK-------AVADQATQNNSSHGSPDSYSLL-----------LNQLKL 1249

Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
            A +E E R+   E+ +   Q  + D  R     AE    A++   N    +++ ++  I 
Sbjct: 1250 AHEELEVRKE--EVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA--IE 1305

Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
                +  T ++  D   L ++       LG   + ++  A  L  QL+ ++   E     
Sbjct: 1306 AYHGVCQTNSKTEDWGYLNEDG-----ELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEH 1360

Query: 1424 LQTAQAQLSEWRRRQEE---EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGR 1480
            L+     L E   +Q++   +   L    +      +E   LT    +  E V++LE+  
Sbjct: 1361 LKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNE 1420

Query: 1481 RRLQQELD---DATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1519
            R+L+++L        DLE  + L  +  K+     Q+  + K
Sbjct: 1421 RKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%)

Query: 1374 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1433
            ++  A++  Q   RA + + +  RAM       +  +E +A           T Q  +  
Sbjct: 824  RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873

Query: 1434 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1489
            W  R+      +A  +        +A RE +AL    A   E + RL  G   ++ ++  
Sbjct: 874  WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929

Query: 1490 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1549
                +++Q +   TL ++       L+   +     VE  ++     ++      SL R 
Sbjct: 930  LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981

Query: 1550 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1609
             EE +  R EL+R +   +   +A    KD++ K V +LE+   + +     L  Q+   
Sbjct: 982  QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038

Query: 1610 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1669
               L  ++D   +  V    +K + E +          R + L K+    E   D  R +
Sbjct: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087

Query: 1670 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1729
             T+     K+  G       Q +        ++          ++  ++VEE    +  +
Sbjct: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141

Query: 1730 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1780
              +   + +KR++ LE E  +LQ   E+    D  + QA+      D D  AD +A  +L
Sbjct: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200

Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1837
             +  +  E ++L+  L +L + + ++  Q+NS   + D Y  LL Q++    EL   +  
Sbjct: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260

Query: 1838 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1891
                 +  Q +    + L GR  E +  AR+      +H     A+E+     +   + E
Sbjct: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318

Query: 1892 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1951
                +     +  A + LK+V       R +  QL+ Q  +    V+ LK QLE  +EE 
Sbjct: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372

Query: 1952 SRAQ 1955
             + Q
Sbjct: 1373 DKQQ 1376



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%)

Query: 1106 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
            K R+EL+ L  R++  S+E L+   V  + +  +L+ ++  + +E +             
Sbjct: 898  KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943

Query: 1165 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
              L + L    +      E L+ E V   ++  E     L EE+E+LR EL+        
Sbjct: 944  --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001

Query: 1223 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1282
             ++  S+ + E+ +    LE+E  + +    E  Q + Q L +  ++  Q    +   +K
Sbjct: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058

Query: 1283 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1342
                   E+ E R+   +L     + EQR   L  ++  ++   G               
Sbjct: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101

Query: 1343 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1398
                  N S   +++   +I  S E+  TE  L   +E+  E+        L L  RVR 
Sbjct: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155

Query: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1458
            +E E   L+ QLE+      R  ++ +  QA+  +     +  A  L      R+    E
Sbjct: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208

Query: 1459 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518
             + L   L E  + V              D  ++ L Q +     LE ++ +   L  + 
Sbjct: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268

Query: 1519 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1574
             +A      ++ R      E    A S     E+  +  + +E  +   +   +      
Sbjct: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322

Query: 1575 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1619
            L+   ++G +   L++  R+ E           +    L+AQ+  L++E+   +      
Sbjct: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382

Query: 1620 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1671
                 + ++E  VQ   +  T    DL+   E  E+  R+L KQL+    +  +    + 
Sbjct: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442

Query: 1672 LAVAARKKLE 1681
            LA + RK+ E
Sbjct: 1443 LAQSERKRHE 1452


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  549 bits (1415), Expect = e-156
 Identities = 446/1446 (30%), Positives = 696/1446 (48%), Gaps = 164/1446 (11%)

Query: 50   WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103
            +T    VW+P     +++A +  +   G++   + L E G  L     P       NP  
Sbjct: 7    YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65

Query: 104  FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162
                 D+  L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYKQLPIY +AI+  Y
Sbjct: 66   LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125

Query: 163  RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222
             G+   ++ PH++AV E AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S 
Sbjct: 126  SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185

Query: 223  KGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAG 282
                           S   +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD   
Sbjct: 186  ---------------SNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQN 230

Query: 283  YIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGP 342
             I+GAN+ TYLLEKSR + Q+++E ++HIFYQL   A +     L L     + +   G 
Sbjct: 231  QIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGG 290

Query: 343  SS--SPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMP 400
            ++      +R    ET ++  +LGF  +  + + ++++A+L  GN+ +    N   +   
Sbjct: 291  NTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE 350

Query: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLF 460
            D++  +  C LLGL     ++ L   +I    + V K  T+ QA  A +ALAK  Y  LF
Sbjct: 351  DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLF 410

Query: 461  RWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFV 520
             ++V R+N+AL  S +Q  +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN  +F 
Sbjct: 411  DFIVERINQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFK 469

Query: 521  LEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKV 580
            LEQEEY +E IPWT +DF  D QP IDLIE      G+L LLDEEC  P  TD+++++K+
Sbjct: 470  LEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKL 525

Query: 581  AQE-QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639
                   +P F++PR       F + H+A KV+YK   +L KN D + D +  +L  S  
Sbjct: 526  YNNFVNRNPLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKF 583

Query: 640  RLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPP 699
             L A  +++              PPSP GS     SA            +QV        
Sbjct: 584  HLCANFFQE-----------NPTPPSPFGSMITVKSA------------KQVI------- 613

Query: 700  GGRPRRGMFR-TVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLR 758
              +P    FR TVG  ++ SL  LM TL+ T P +VRCI PN EK   + + + ++ QLR
Sbjct: 614  --KPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLR 671

Query: 759  CNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNL 818
              GVLE IRI  Q +P+R  + EF  RY IL        F D K+ C+ ++  L  D N 
Sbjct: 672  ACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKKEVCKVVLHRLIQDSNQ 730

Query: 819  YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQ--------- 869
            Y+ G++KIFFRAG +A LE+ R  K+    V  Q   RG+L R+ F + ++         
Sbjct: 731  YQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYF 790

Query: 870  --QQS--------------ALRVMQRNCAAYLKLRHWQWWRLFTKV-----KPLLQVTRQ 908
              QQ+              A  ++Q++C  YL    +Q  R+ T       +  L   R 
Sbjct: 791  RGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRY 850

Query: 909  DEVLQA-RAQELQKVQE---------------LQQQSAREVGELQGRVAQLEEERARLAE 952
             ++L+  +A  LQK                  L  Q    V  LQ ++    +E   L E
Sbjct: 851  RKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVE 910

Query: 953  QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK--RLQQHI 1010
            +L + A L A   E       +K E EL  +    R  EE+    +   E+K  +LQ+H 
Sbjct: 911  KLTSLAALRAGDVE-----KIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHN 965

Query: 1011 QELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED----RL 1066
             ELE   E     + +L+L++ T E K +K +     L D   K  ++R LLE     + 
Sbjct: 966  SELETQKE-----QIQLKLQEKTEELK-EKMDNLTKQLFDDVQKEERQRMLLEKSFELKT 1019

Query: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIAD---MEDRLRKEEKGRQELEKLKRRLDGESS 1123
             ++  Q    +E++K+L   +++ +  +       D L+ E     +  K     + E  
Sbjct: 1020 QDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079

Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL----LKSLREAQAALA 1179
             LQ Q ++ ++  +  + ++  K  E+   L  + D    R++L    L+ L E    L 
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNE-DGELW 1138

Query: 1180 EAQEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238
             A E L ++ RV  +  + Q+    +E+EAL  ++                  QE+  L+
Sbjct: 1139 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHL--------------SQEINHLQ 1184

Query: 1239 KTLEEETRIHEAAVQELRQ--RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296
            K   EE  I+E+   E+ +       + +  +Q+ +  + K   E  RL  +AE  + + 
Sbjct: 1185 KLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLE-IRLNEQAEKMKGKL 1243

Query: 1297 ELSSLQTARQEGEQRRRRLELQLQ-EVQGRAGDGERARAEAAEKLQRAQAELENVSGALN 1355
            E  S Q  R + E+  +R  L+ Q E+        + + +  +K+Q  Q   +++     
Sbjct: 1244 EELSNQLHRSQEEEGTQRKALEAQNEIH------TKEKEKLIDKIQEMQEASDHLKKQFE 1297

Query: 1356 EAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA 1415
                      +E S    +  D +E L  + R    L  +V+ + ++  G    +   + 
Sbjct: 1298 TESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTL-SKTIGKANDVHSSSG 1356

Query: 1416 ARERAG 1421
             +E  G
Sbjct: 1357 PKEYLG 1362



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%)

Query: 1508 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1565
            +R++ ++L E KA +L+        R   +   R    + LT  +   Q  +++LE QN+
Sbjct: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903

Query: 1566 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1625
                 +E L S        V ++++     E+AA   R    + +    A E+   +L+ 
Sbjct: 904  ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963

Query: 1626 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1676
                L+TQ E+    LQ + E  +E+   L KQL D +V+++E  +QR L   +      
Sbjct: 964  HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020

Query: 1677 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1721
               K+++   EE+KA      Q             G +  V +L K    + E  +E+E 
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080

Query: 1722 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1774
             +  +    + + SQ RE  +++  +  ++L   E     D   R + +D + + ++   
Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137

Query: 1775 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1820
              A   L KA  +LE            E   L  ++  L +E+   Q      ND    +
Sbjct: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197

Query: 1821 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1880
              +V  LT+E      F  +      +LE+Q Q+L  RL E+      + K  +  L ++
Sbjct: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249

Query: 1881 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1940
            L +++E+ E   R+ + +   +   EK  ++++ +++E +  +D L+ Q E  +  VK  
Sbjct: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305

Query: 1941 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1982
             RQ      EASR     R L+ EL+      + +  +V TL
Sbjct: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%)

Query: 1132 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
            Q  R   L  QL  + + LQ  L     E     + L SL   +A   E  + LE+E   
Sbjct: 876  QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933

Query: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
              KA   RR+  E+ +  R  +E+ L      Q+  S+ E +  +++  L+E+T      
Sbjct: 934  -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983

Query: 1252 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1311
             +EL+++      +L + +++  R +   EK+    E +  +   ++ SL+   +  +  
Sbjct: 984  -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039

Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
            + +L+  L E +    DG +A      K  +  +E E                 KE+   
Sbjct: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081

Query: 1372 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1428
            +AQ  D ++ +Q    E R K++  ++      +   +R +L  E         EL  A 
Sbjct: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141

Query: 1429 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1487
              L +  R        LE+  ++++    +E EAL  ++   ++ ++ L++    L +E 
Sbjct: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190

Query: 1488 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1546
            +D    +  +   +++       F Q ++E EK      +   E+AE    + E  +  L
Sbjct: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250

Query: 1547 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1599
             R+ EEE   R+ LE QN     E E L+    ++ ++   L++             Q A
Sbjct: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310

Query: 1600 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1630
            + L  +  +LE+EL   +    +L+  V+ L
Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%)

Query: 904  QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 963
            Q+    E ++A   E  ++Q L +        L+  VA+L ++   ++E  +    L A+
Sbjct: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084

Query: 964  AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 1019
              +    + ++K+E+   +SE+  ++ E    S  ++  + RL     +H+ E      A
Sbjct: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140

Query: 1020 EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1076
             EG ++  ++ +   +++   +E+++  L  +   LS+E   L+    E    +     E
Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200

Query: 1077 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1133
              ++ S N +   ++  I+++E + +  E +  ++ EK+K +L+  S++L     E+  Q
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260

Query: 1134 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
            ++A E + ++  KE        +E+Q A    + +    +++  + R+  + L     DL
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320

Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1233
            E E   + +  K+ +D  + L    G+  D   S+  ++    L+ KRE E
Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  536 bits (1381), Expect = e-152
 Identities = 464/1502 (30%), Positives = 724/1502 (48%), Gaps = 139/1502 (9%)

Query: 56   VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
            VW+P     +++A L  + +   +V L   E G+ L    D   +      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 109  DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
            D+  L+ L+E +VLHNLR R+  S LIYTY G+  V INPY+QLPIY E I+  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 168  HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
             ++ PH++AV E AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186

Query: 228  PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
                      S   +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD    I+GA
Sbjct: 187  ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237

Query: 288  NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
            N+ TYLLEKSR + QA++E ++HIFYQL   A       L L    ++ +   G  P   
Sbjct: 238  NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297

Query: 346  PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
               + +    T ++  +LG S    + + R+++ +L  GN+     R+ D  T+P     
Sbjct: 298  GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356

Query: 406  QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
              + C L+G+   +    L   ++    +   K  +K QA  A +ALAK  Y +LF W+V
Sbjct: 357  LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416

Query: 465  LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
              +N+AL  + +Q  SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQE
Sbjct: 417  DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475

Query: 525  EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
            EY +E IPWT +DF  D QPCI+LIE   +  G+L LLDEEC  PK TD ++ +K+    
Sbjct: 476  EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531

Query: 585  -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
                  F++PR L ++A F + H+A KV+Y+   +L KN D + +    +L  S  ++  
Sbjct: 532  LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589

Query: 644  EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
            E+++D+                          AISP       G   ++     P  GRP
Sbjct: 590  ELFQDD------------------------EKAISPTSATS-SGRTPLTRTPAKPTKGRP 624

Query: 704  ---RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCN 760
                +   +TVG  ++ SL  LM TL+ T P +VRCI PN  K     + +  + QLR  
Sbjct: 625  GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRAC 684

Query: 761  GVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYR 820
            GVLE IRI   GFP+R  +QEF  RY +L          D KQ C+ +++ L LD + Y+
Sbjct: 685  GVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQ 742

Query: 821  VGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 880
             G++KIFFRAG +A LE+ R  K+    +  Q   RG+L R+   K  + + A   MQR 
Sbjct: 743  FGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRY 799

Query: 881  CAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRV 940
               Y + R +  +   TK   ++Q   +  V++ R  ++++   +  QS      L+G +
Sbjct: 800  VRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR-RRYKIRRAATIVLQS-----YLRGFL 852

Query: 941  AQLEEERARLAEQLRAEAELCAEAEETRGRLAAR--KQELELVVSELEARVGEEEECSRQ 998
            A     R R  + LR    +  + +  RG LA    K+ +  ++          + C R+
Sbjct: 853  A-----RNRYRKILREHKAVIIQ-KRVRGWLARTHYKRSMHAII--------YLQCCFRR 898

Query: 999  M--QTEKKRLQQHIQELEAHLEAEEGARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QN 1052
            M  + E K+L+   + +E + +   G   K +QL++   E     K   E L  LE   N
Sbjct: 899  MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958

Query: 1053 SKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE- 1110
            S+  K R  LE RL     Q +EEE KV +   L L+ E A +    ++ R E+K  +E 
Sbjct: 959  SETEKLRSDLE-RL-----QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012

Query: 1111 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL--- 1167
             ++ K+  +   S L+E+    +Q  E L  ++ ++ +E+   + +   E   + +L   
Sbjct: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072

Query: 1168 -----LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
                  ++L    + L E  +DL+ E        K      +   +   E E    S  A
Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIA 1131

Query: 1223 QQELRSKREQEVTELKKTLEEETRIH-EAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
            + E    R +E +E K  L+    +  +  V EL Q       EL  + EQ  R K    
Sbjct: 1132 EMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSK---- 1187

Query: 1282 KTRLALEAEVSELR-AELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAE 1338
                A E E  ++R AEL      RQE E   ++L+ +L E++    +       A  A 
Sbjct: 1188 ----AKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP 1243

Query: 1339 KLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRA 1398
              +    +L +VS  L+  + + + L        +QL   +E +Q +        S +  
Sbjct: 1244 AYRVLMEQLTSVSEELDVRKEEVLIL-------RSQLVSQKEAIQPKDDKNTMTDSTILL 1296

Query: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAR 1457
             + +    + ++ +     +   R L   ++QL   +R  E EA AL    +  +    R
Sbjct: 1297 EDVQKMKDKGEIAQAYIGLKETNRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNR 1353

Query: 1458 EAEALTQ--RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1515
            + + L Q  +L  +      L+    RL  E  D    LE+Q + V  L+K+ + F + +
Sbjct: 1354 QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1413

Query: 1516 AE 1517
             E
Sbjct: 1414 GE 1415



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 129/620 (20%), Positives = 244/620 (39%), Gaps = 106/620 (17%)

Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
            S    ++L    E ++ +L++ ++E+ + ++  V++L    G                  
Sbjct: 914  SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955

Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1337
                      +E  +LR++L  LQ + +E +    R+    +E+     D E+ R+E   
Sbjct: 956  -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008

Query: 1338 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1395
              E   R + E E +   L E  +    L +E  +   ++    + + E    KL   ++
Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065

Query: 1396 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1451
               ++     LR Q  L E +   ER    +E  T    + +   ++ +   +    E  
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125

Query: 1452 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1511
                  E E +  R  E +E    L            D ++ L+ Q+++    ++KQ   
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173

Query: 1512 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1571
            D+L  +E+  +    +E ER +  G E           LE E   R+ELE +N+ L+ EL
Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222

Query: 1572 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK 1631
              L  +  +  KS  E+         A   L  Q+T + +EL   ++  L L      L 
Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILR---SQLV 1274

Query: 1632 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE-ERKQRTLAVAARKKLEGELEELKAQ 1690
            +Q E  +Q +D+        +   L D +  +D+ E  Q  + +    +L      L++Q
Sbjct: 1275 SQKEA-IQPKDDKNTMTDSTIL--LEDVQKMKDKGEIAQAYIGLKETNRL------LESQ 1325

Query: 1691 MASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKG------ 1742
            + S  +  E   + LR     +KE     E  R  ++++ +QN +   E R++       
Sbjct: 1326 LQSQKRSHENEAEALRGEIQSLKE-----ENNR--QQQLLAQNLQLPPEARIEASLQHEI 1378

Query: 1743 --LEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GNLSKAAILEE------ 1788
              L  E L L E+L   D+  R+ ++     A ++         N+S   I++E      
Sbjct: 1379 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVN 1438

Query: 1789 -KRQLEGRLGQLEEELEEEQ 1807
              R+ +   G LE + E+EQ
Sbjct: 1439 IPRKEKDFQGMLEYKKEDEQ 1458



 Score = 65.1 bits (157), Expect = 7e-10
 Identities = 103/551 (18%), Positives = 229/551 (41%), Gaps = 92/551 (16%)

Query: 1464 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
            ++L  +  +V+R ++    ++ ++      +++Q +    L +K    + +   E   + 
Sbjct: 906  KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965

Query: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGK 1583
              +E  + +E E +    R LSL          +EE+ +    LR +LE   S K    K
Sbjct: 966  SDLERLQLSEEEAKVATGRVLSL----------QEEIAK----LRKDLEQTRSEK----K 1007

Query: 1584 SVHE-LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRD 1642
             + E  +R  +  EQ  ++L+ + T L+ E  A                  + R +Q   
Sbjct: 1008 CIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL-----------------NHRIVQQAK 1050

Query: 1643 EAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA------SAGQ 1696
            E  E   ++L ++ +  E++ ++ER +    +    +LE   ++LK +M         G 
Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGH 1110

Query: 1697 GKEEAVKQLRKMQ-------AQMKELWREVEETRTSREEI-FSQNRESEKRLKGLEAEVL 1748
             + ++     + +       A+M+++    EE    +  +  S   + +KR+  LE E  
Sbjct: 1111 KRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ 1170

Query: 1749 RLQEELAASD----RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1804
             +Q+EL   +    R++ + ++       E+   +L +  +  E ++L+  L +L + L 
Sbjct: 1171 VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230

Query: 1805 EEQSNSELLNDR--YRKLLLQVESLTTELSAERS----FSAKAESGRQQLE--------- 1849
            E+ +          YR L+ Q+ S++ EL   +       ++  S ++ ++         
Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT 1290

Query: 1850 ------RQIQELR--GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
                    +Q+++  G + +   G +  +++  + L+S+    E + E   R  I S K 
Sbjct: 1291 DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEA-LRGEIQSLKE 1349

Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLR--------------DQLEKGNLRVKQLKRQLEEA 1947
                +++L    LQ+  E R+   L+              +QLEK +  V++LK+QL+  
Sbjct: 1350 ENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVF 1409

Query: 1948 EEEASRAQAGR 1958
             ++    + G+
Sbjct: 1410 AKKIGELEVGQ 1420



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%)

Query: 1792 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1851
            +E ++ QL+ +++E+  + + L          VE LT   + E  ++++ E  R  LER 
Sbjct: 925  MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971

Query: 1852 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1911
                  +L EE+A         + +L+ ++A+  + LEQ   E+    +   R ++  ++
Sbjct: 972  ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022

Query: 1912 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1971
            +V  ++EE  +  Q ++ L   N R+ Q  +++ E  E+  +     ++L+ +L D    
Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077

Query: 1972 AESMNREVTTLRNR 1985
             +++  E + L  R
Sbjct: 1078 YQNLLNEFSRLEER 1091


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  534 bits (1375), Expect = e-151
 Identities = 470/1522 (30%), Positives = 731/1522 (48%), Gaps = 152/1522 (9%)

Query: 56   VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
            VW+P     +++A L  + +   +V L   E G+ L    D   +      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 109  DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
            D+  L+ L+E +VLHNLR R+  S LIYTY G+  V INPY+QLPIY E I+  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 168  HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
             ++ PH++AV E AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186

Query: 228  PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
                      S   +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD    I+GA
Sbjct: 187  ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237

Query: 288  NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
            N+ TYLLEKSR + QA++E ++HIFYQL   A       L L    ++ +   G  P   
Sbjct: 238  NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297

Query: 346  PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
               + +    T ++  +LG S    + + R+++ +L  GN+     R+ D  T+P     
Sbjct: 298  GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356

Query: 406  QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
              + C L+G+   +    L   ++    +   K  +K QA  A +ALAK  Y +LF W+V
Sbjct: 357  LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416

Query: 465  LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
              +N+AL  + +Q  SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQE
Sbjct: 417  DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475

Query: 525  EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
            EY +E IPWT +DF  D QPCI+LIE   +  G+L LLDEEC  PK TD ++ +K+    
Sbjct: 476  EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531

Query: 585  -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
                  F++PR L ++A F + H+A KV+Y+   +L KN D + +    +L  S  ++  
Sbjct: 532  LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589

Query: 644  EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
            E+++D+                          AISP       G   ++     P  GRP
Sbjct: 590  ELFQDD------------------------EKAISPTSATS-SGRTPLTRTPAKPTKGRP 624

Query: 704  ---RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCN 760
                +   +TVG  ++ SL  LM TL+ T P +VRCI PN  K     + +  + QLR  
Sbjct: 625  GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRAC 684

Query: 761  GVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYR 820
            GVLE IRI   GFP+R  +QEF  RY +L          D KQ C+ +++ L LD + Y+
Sbjct: 685  GVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQ 742

Query: 821  VGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 880
             G++KIFFRAG +A LE+ R  K+    +  Q   RG+L R+   K  + + A   MQR 
Sbjct: 743  FGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRY 799

Query: 881  CAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRV 940
               Y + R +  +   TK   ++Q   +  V++ R  ++++   +  QS      L+G +
Sbjct: 800  VRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR-RRYKIRRAATIVLQS-----YLRGFL 852

Query: 941  AQLEEERARLAEQLRAEAELCAEAEETRGRLAAR--KQELELVVSELEARVGEEEECSRQ 998
            A     R R  + LR    +  + +  RG LA    K+ +  ++          + C R+
Sbjct: 853  A-----RNRYRKILREHKAVIIQ-KRVRGWLARTHYKRSMHAII--------YLQCCFRR 898

Query: 999  M--QTEKKRLQQHIQELEAHLEAEEGARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QN 1052
            M  + E K+L+   + +E + +   G   K +QL++   E     K   E L  LE   N
Sbjct: 899  MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958

Query: 1053 SKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE- 1110
            S+  K R  LE RL     Q +EEE KV +   L L+ E A +    ++ R E+K  +E 
Sbjct: 959  SETEKLRSDLE-RL-----QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012

Query: 1111 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL--- 1167
             ++ K+  +   S L+E+    +Q  E L  ++ ++ +E+   + +   E   + +L   
Sbjct: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072

Query: 1168 -----LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
                  ++L    + L E  +DL+ E        K      +   +   E E    S  A
Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIA 1131

Query: 1223 QQELRSKREQEVTELKKTLEEETRIH-EAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
            + E    R +E +E K  L+    +  +  V EL Q       EL  + EQ  R K    
Sbjct: 1132 EMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSK---- 1187

Query: 1282 KTRLALEAEVSELR-AELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAE 1338
                A E E  ++R AEL      RQE E   ++L+ +L E++    +       A  A 
Sbjct: 1188 ----AKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP 1243

Query: 1339 KLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ----------------LHDAQELL 1382
              +    +L +VS  L+  + + + L  +L S +                  L D Q++ 
Sbjct: 1244 AYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK 1303

Query: 1383 QEETRAKLALG----SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1438
             +   A+  +G    +R  A++        +L       ++A R L   ++QL   +R  
Sbjct: 1304 DKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLL---ESQLQSQKRSH 1360

Query: 1439 EEEAGALEAG-EEARRRAAREAEALTQ--RLAEKTETVDRLERGRRRLQQELDDATMDLE 1495
            E EA AL    +  +    R+ + L Q  +L  +      L+    RL  E  D    LE
Sbjct: 1361 ENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLE 1420

Query: 1496 QQRQLVSTLEKKQRKFDQLLAE 1517
            +Q + V  L+K+ + F + + E
Sbjct: 1421 KQDKTVRKLKKQLKVFAKKIGE 1442



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 141/606 (23%), Positives = 240/606 (39%), Gaps = 133/606 (21%)

Query: 1369 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1424
            S TE    D + L   E  AK+A G RV +++ E A LR+ LE    E+    E A R  
Sbjct: 959  SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017

Query: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1484
            Q  +  +S  +    EE   L+  +EA          + Q+  E TET+++      +L 
Sbjct: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEK------KLV 1061

Query: 1485 QELDDATMDLEQQR----QLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1540
            +E     +DL  +R     L++   + + ++D L  E    V       +R ++     E
Sbjct: 1062 EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNE 1121

Query: 1541 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1600
            +  +  +   E E       E   + +  ++   L                         
Sbjct: 1122 SEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK------------------------ 1157

Query: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660
             L+ +VTELE E    +D   R E  V             R +A EE R     Q+R AE
Sbjct: 1158 -LQKRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAE 1200

Query: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720
            +E +  ++Q     +  KKL+ EL EL+  ++          K   ++ A     +R + 
Sbjct: 1201 LEYESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLM 1249

Query: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780
            E  TS  E     +E          EVL L+ +L +   A  Q + D++ M D       
Sbjct: 1250 EQLTSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI---- 1294

Query: 1781 SKAAILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAE 1834
                +LE+ ++++  G + Q    L+E   +S L    LN+   +L L  E L     A 
Sbjct: 1295 ----LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QAN 1346

Query: 1835 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1894
            R   ++ +S ++  E + + LRG                I +L+          E   ++
Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQ 1382

Query: 1895 RILSGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEAS 1952
            ++L+  L    E R+ E  LQ E  R   + L   +QLEK +  V++LK+QL+   ++  
Sbjct: 1383 QLLAQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIG 1441

Query: 1953 RAQAGR 1958
              + G+
Sbjct: 1442 ELEVGQ 1447



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%)

Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
            S    ++L    E ++ +L++ ++E+ + ++  V++L    G                  
Sbjct: 914  SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955

Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1337
                      +E  +LR++L  LQ + +E +    R+    +E+     D E+ R+E   
Sbjct: 956  -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008

Query: 1338 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1395
              E   R + E E +   L E  +    L +E  +   ++    + + E    KL   ++
Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065

Query: 1396 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1451
               ++     LR Q  L E +   ER    +E  T    + +   ++ +   +    E  
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125

Query: 1452 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1511
                  E E +  R  E +E    L            D ++ L+ Q+++    ++KQ   
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173

Query: 1512 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1571
            D+L  +E+  +    +E ER +  G E           LE E   R+ELE +N+ L+ EL
Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222

Query: 1572 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1627
              L  +  +  KS  E+         A   L  Q+T + +EL   ++  L L   +    
Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277

Query: 1628 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1674
            +A++ + ++           D+Q   + GE  +    L +  R + ++  E  +   L +
Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337

Query: 1675 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
                   A + LE +L+  K      A A +G+ +++K+    Q Q+  L + ++    +
Sbjct: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395

Query: 1726 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1779
            R E   Q+      +  L  E L L E+L   D+  R+ ++     A ++         N
Sbjct: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450

Query: 1780 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1807
            +S   I++E        R+ +   G LE + E+EQ
Sbjct: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%)

Query: 1792 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1851
            +E ++ QL+ +++E+  + + L          VE LT   + E  ++++ E  R  LER 
Sbjct: 925  MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971

Query: 1852 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1911
                  +L EE+A         + +L+ ++A+  + LEQ   E+    +   R ++  ++
Sbjct: 972  ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022

Query: 1912 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1971
            +V  ++EE  +  Q ++ L   N R+ Q  +++ E  E+  +     ++L+ +L D    
Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077

Query: 1972 AESMNREVTTLRNR 1985
             +++  E + L  R
Sbjct: 1078 YQNLLNEFSRLEER 1091


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  531 bits (1369), Expect = e-150
 Identities = 445/1693 (26%), Positives = 793/1693 (46%), Gaps = 189/1693 (11%)

Query: 50   WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
            W     VW+     GF  A+ L+ E     E +  V+L   G  L +  D +++ N P  
Sbjct: 346  WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404

Query: 105  SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
             + ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +Y+E ++ M++G
Sbjct: 405  DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464

Query: 165  KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
             +R ++ PH+YAV + AYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A    G
Sbjct: 465  CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523

Query: 225  RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
             K   V    +  +             +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 524  NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570

Query: 285  VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
              A+I+T LLEK R  R+   E +F++FY LL      L+ +L L   +        P +
Sbjct: 571  ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630

Query: 345  SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
             P ++++    F +   +++VLG S +E  +   +++A+   G   A K      +    
Sbjct: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690

Query: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
             +  AQK   LLG  + + S A+   + K G   +Q++ +  Q                A
Sbjct: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748

Query: 445  DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
               LE +A   Y  LF  LV  +NRAL  S     S + I+D  GF+  +        SF
Sbjct: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807

Query: 499  EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
            E+LC NYT ++LQ+LF+   FV E E Y+ E I   F D        +  +++ ++    
Sbjct: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867

Query: 557  ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
                      GLL LL+EE   P A++ + +E++    G   G  K Q P  H      F
Sbjct: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927

Query: 603  SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFL 659
             + H  G   V+Y    WL     +P   N   LL  S  ++ + +            FL
Sbjct: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNL------------FL 975

Query: 660  GSFPPSPPGSAERCSSAISPPGVEG--IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKE 717
            G       GSA   S +I+  G+EG   + L + +S+         R+     +  + K+
Sbjct: 976  GR-----AGSATVLSGSIA--GLEGGSQLALRRATSM---------RKTFTTGMAAVKKK 1019

Query: 718  SL--------SRLMATLSNTNPSFVRCIVPNHEKRAGK---------------------- 747
            SL          L+ T+  +   FV C +P  E  AG+                      
Sbjct: 1020 SLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDH 1079

Query: 748  -------LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG--- 797
                   L+  L+  QLR + +L+ +R+ RQG+P+ ++F EFR+R+++L P+   K    
Sbjct: 1080 CEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRN 1139

Query: 798  --FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 855
               +D ++A E++++ L+L+ +   +G S++FFRAG LA+LEE+RD + +  +  FQAA 
Sbjct: 1140 YIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAAC 1199

Query: 856  RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 915
            RGYLAR+ F+KR+ Q  A+R +Q+N      ++ W WW+LFT V+PL++V   +E ++ +
Sbjct: 1200 RGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK 1259

Query: 916  AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 975
             +E+Q+++   +++ +E  EL+    +LE   + L  +L  E      A +      A +
Sbjct: 1260 DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAER 1319

Query: 976  QELELVVSELEARVGEEEECSRQMQTEKKRLQQH--IQELEAHLEAEE---GARQKLQLE 1030
               E  + EL+    + +   +QM+  +  + +   I+  E + E ++   G   +L+ E
Sbjct: 1320 LRAEKEMKELQT---QYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376

Query: 1031 KVT-----TEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
            +       T+ ++++  ED L +E QN      ++ LE RL +  + + E +  ++ L K
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLERRLGDLQADSEESQRALQQLKK 1430

Query: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1145
               +  A + D +  L  ++    ELEK +RR D E S+  E+   ++ + E+L+ +   
Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490

Query: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205
               E  +   + E++    A   + +   +A L +       +  +  K +KQ RDL  +
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550

Query: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
            ++    EL++   +    ++ + + E E+  +++T  +E    +  V+E RQ   + L +
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ 1610

Query: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1325
            +  QLE+    K    + +  LE +++ L     S Q  R++ E   +RL   L+  +  
Sbjct: 1611 MEVQLEEEYEDKQKVLREKRELEGKLATL-----SDQVNRRDFES-EKRLRKDLKRTKAL 1664

Query: 1326 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEE 1385
              D +    +  +    ++ E+  +   L E+E       K   + E ++ D    + + 
Sbjct: 1665 LADAQ-LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723

Query: 1386 TRAKLALGSRVRAMEAEAAGLREQLEEE-----------AAARERAGREL---QTAQAQL 1431
             +AK AL  ++  ++ E   ++ +LEE+            AA  +A R+L      QAQL
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1783

Query: 1432 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
             E  + ++E    L+A +        + E L Q + +K+  V R E   R L+  L+   
Sbjct: 1784 EEANKEKQELQEKLQALQS-------QVEFLEQSMVDKS-LVSRQEAKIRELETRLEFER 1835

Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALE 1551
              +++   L S L++   K  +   +  AA  R  E+ +R + + R+ +     L R   
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA 1895

Query: 1552 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELED 1611
            E    + ELE    +L A  ++L +      K + +L+ A    E  +++    +  L+D
Sbjct: 1896 EASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE-DEMESDENEDLINSLQD 1954

Query: 1612 ELTAAEDAKLRLE 1624
             +T  +  K +LE
Sbjct: 1955 MVTKYQKRKNKLE 1967



 Score =  192 bits (489), Expect = 2e-48
 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)

Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
            R  +E+QL E Q R  D E  +  +  KL++A+ E   +    +  ES+   L+ EL+  
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301

Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1411
                  A +LL  ET  +L     ++ ++ +   L++Q+E                    
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361

Query: 1412 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468
               ++A    R   E    +   ++ R +QE E   LE  ++ +R+  R    L     E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420

Query: 1469 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
                + +L++  +RL  EL D  + LE Q+     LEKKQR+FD  L++      R   +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480

Query: 1529 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588
            RE+ + E     A A SL + LEE+        ++  +L AEL+ + S +     S+ ++
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540

Query: 1589 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648
            ++  R  E    D   ++ E    +   E AKLRLE+ ++ ++  H ++++ RDE  EE 
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600

Query: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
            R+   K+L+  EV+ +EE + +   +  +++LEG+L  L  Q+    +   E+ K+LRK 
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657

Query: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1768
              + K L  + +       +    +  S++ +  L+ ++   +   AA+ +AR+  + + 
Sbjct: 1658 LKRTKALLADAQ----LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713

Query: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1828
            +++  ++ +   +K A+ E+  +L+    +++  LEE+Q +   L  +++  + Q     
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773

Query: 1829 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1888
             +++  ++   +A   +Q+L+ ++Q L+ ++  E        K  ++  E+K+ + E +L
Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831

Query: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1946
            E E  +     K +     RLKE + ++ EER  R+A + R++ +      K+L+RQL +
Sbjct: 1832 EFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882

Query: 1947 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1979
             +E   E +R +A   R + ELE   ES E+ N+ +
Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918



 Score =  157 bits (396), Expect = 1e-37
 Identities = 164/804 (20%), Positives = 350/804 (43%), Gaps = 121/804 (15%)

Query: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
            +EQ+  + +  ++LR++L + E+E       ++      ++L   L + +     A + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312

Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1227
            ++E   R +AEK+ ++L  + +AL+ ++E                    +D  +A  E R
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372

Query: 1228 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
             K E+ V E+   KK L++E        Q+ +++  + LG+L    E+++R     +K  
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432

Query: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344
              L AE+ + +  L   Q    E E+++RR + +L +    A           EKLQR  
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482

Query: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
                              +L +E     A+    ++ L+E+         +V ++EAE  
Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524

Query: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1464
             +  Q  ++ A+  +  ++L+  +A++ +     +E+AG ++  E+A+ R   E E + Q
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584

Query: 1465 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
              +++ E+ D  +E  R+  Q++L    + LE++                   E+K  VL
Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626

Query: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1576
            R     E+ E EG+          R  E E+  R++L+R  +AL A+ + +L        
Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680

Query: 1577 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1626
            SK ++ +  ++LE          +A +  E    DL  Q+ ++    TA E+   RL+  
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740

Query: 1627 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1680
               ++ + E D +  +E  ++ +  +A+      Q+ D + + +E  K++       + L
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800

Query: 1681 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1724
            + ++E L+  M       ++EA               VK+L  + +++KE   ++ E R 
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860

Query: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
             R  I ++NRE E+  K L+ ++   +EE+    R   +A + + E+  ++ +   +  +
Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917

Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1844
            +  + +    R+G L+  +E+E       +D    L+  ++ + T+    ++        
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEME-----SDENEDLINSLQDMVTKYQKRKNKLEGDSDV 1972

Query: 1845 RQQLERQIQELRGRLGEEDAGARA 1868
              +LE ++  ++  L +    ++A
Sbjct: 1973 DSELEDRVDGVKSWLSKNKGPSKA 1996



 Score =  116 bits (291), Expect = 2e-25
 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)

Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
            V   E++ R  D+ + + ++ + +A +ER          E+R   LT  L +E+   E  
Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308

Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1616
             +   A  AE         ++      L++   V E    + R    A++    D+  A 
Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368

Query: 1617 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
             + +L+ E  V+ +   K + +++ + + E  ++ +RQL ++L D  ++ D E  QR L 
Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426

Query: 1674 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1731
               +K  +L  EL++ K  +        E  K+ R+  +++ +   E +  +  RE++  
Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484

Query: 1732 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1784
              RE +  L    AE   L+++L   D       +     + +  +++ + +    S A 
Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539

Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1843
            + ++ R LE ++   EEEL+E+    ++L     +L +++E +    S E  S   + E 
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599

Query: 1844 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
             RQ  +++++++  +L EE  D     R K     LE KLA   +Q+ +   E   S K 
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653

Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
            +R+  KR K ++   +    + D L++        + QLK QLEE+E   + A   R+ +
Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709

Query: 1962 QRELEDVTESAESMNREVTTLRNRLRR 1988
            + E+ED+    + + +  T L  +L R
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736



 Score =  109 bits (272), Expect = 3e-23
 Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%)

Query: 1428 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1481
            + QLSE + R ++E        LE  E+ R      ++ L  R++E T E  D    G  
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307

Query: 1482 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1537
              Q       +D E   +L +  E K  Q ++D L  + +   +  +E R    AE  G 
Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361

Query: 1538 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1581
                          ER  R +  T+  L++E E + E+E+QN R L   L  L +  ++ 
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421

Query: 1582 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1641
             +++ +L++ C+       D +  +   +      E  + R +  +     + +R+   R
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481

Query: 1642 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1699
            ++   E+   LA+      +++  E K   +A   +K   LE EL+++ +Q +       
Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538

Query: 1700 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1756
            +  KQLR ++A++K+   E++E   + + +       E   +R++   ++ +  ++E   
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597

Query: 1757 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1816
             + AR+  Q+   +M  ++      K  +L EKR+LEG+L  L +++      SE    R
Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653

Query: 1817 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1876
             RK L + ++L  +          +   +    R+I +L+ +L E +         T AA
Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701

Query: 1877 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1936
                  +A + +E E  +  L    + +A+  L+E + +++ E+   ++++++LE+    
Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754

Query: 1937 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
            + +L ++ + A  +ASR  A    LQ +LE+  +  + +  ++  L++++
Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%)

Query: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1776
            R + E + S E+I +++ E ++    LE       E    SDR   +  +   E+ DE  
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303

Query: 1777 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1836
             G  S + +L+          +  E L  E+   E L  +Y  L  Q+E +  E+   R 
Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352

Query: 1837 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1896
              A              E+ G + ++DAG   R K   A  E      +++L+QE  +++
Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397

Query: 1897 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1941
             +  +  R+ E+RL ++    EE +R   QL+ +              LE   +R  +L+
Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457

Query: 1942 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1994
            +       +L +A EEA R +  R +LQRE + +   A S+ +++      +      FT
Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513

Query: 1995 TRTVRQVFRLEEGVASDEEAEEA 2017
             + V     L++ ++S E  +EA
Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  526 bits (1356), Expect = e-149
 Identities = 445/1701 (26%), Positives = 793/1701 (46%), Gaps = 194/1701 (11%)

Query: 50   WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
            W     VW+     GF  A+ L+ E     E +  V+L   G  L +  D +++ N P  
Sbjct: 346  WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404

Query: 105  SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
             + ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +Y+E ++ M++G
Sbjct: 405  DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464

Query: 165  KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
             +R ++ PH+YAV + AYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A    G
Sbjct: 465  CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523

Query: 225  RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
             K   V    +  +             +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 524  NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570

Query: 285  VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
              A+I+T LLEK R  R+   E +F++FY LL      L+ +L L   +        P +
Sbjct: 571  ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630

Query: 345  SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
             P ++++    F +   +++VLG S +E  +   +++A+   G   A K      +    
Sbjct: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690

Query: 401  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
             +  AQK   LLG  + + S A+   + K G   +Q++ +  Q                A
Sbjct: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748

Query: 445  DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
               LE +A   Y  LF  LV  +NRAL  S     S + I+D  GF+  +        SF
Sbjct: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807

Query: 499  EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
            E+LC NYT ++LQ+LF+   FV E E Y+ E I   F D        +  +++ ++    
Sbjct: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867

Query: 557  ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
                      GLL LL+EE   P A++ + +E++    G   G  K Q P  H      F
Sbjct: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927

Query: 603  SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFL 659
             + H  G   V+Y    WL     +P   N   LL  S  ++ + +            FL
Sbjct: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNL------------FL 975

Query: 660  GSFPPSPPGSAERCSSAISPPGVEG--IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKE 717
            G       GSA   S +I+  G+EG   + L + +S+         R+     +  + K+
Sbjct: 976  GR-----AGSATVLSGSIA--GLEGGSQLALRRATSM---------RKTFTTGMAAVKKK 1019

Query: 718  SL--------SRLMATLSNTNPSFVRCIVPNHEKRAGK---------------------- 747
            SL          L+ T+  +   FV C +P  E  AG+                      
Sbjct: 1020 SLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDH 1079

Query: 748  -------LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG--- 797
                   L+  L+  QLR + +L+ +R+ RQG+P+ ++F EFR+R+++L P+   K    
Sbjct: 1080 CEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRN 1139

Query: 798  --FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 855
               +D ++A E++++ L+L+ +   +G S++FFRAG LA+LEE+RD + +  +  FQAA 
Sbjct: 1140 YIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAAC 1199

Query: 856  RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 915
            RGYLAR+ F+KR+ Q  A+R +Q+N      ++ W WW+LFT V+PL++V   +E ++ +
Sbjct: 1200 RGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK 1259

Query: 916  AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 975
             +E+Q+++   +++ +E  EL+    +LE   + L  +L  E      A +      A +
Sbjct: 1260 DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAER 1319

Query: 976  QELELVVSELEARVGEEEECSRQMQTEKKRLQQH--IQELEAHLEAEE---GARQKLQLE 1030
               E  + EL+    + +   +QM+  +  + +   I+  E + E ++   G   +L+ E
Sbjct: 1320 LRAEKEMKELQT---QYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376

Query: 1031 KVT-----TEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
            +       T+ ++++  ED L +E QN      ++ LE RL +  + + E +  ++ L K
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLERRLGDLQADSEESQRALQQLKK 1430

Query: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1145
               +  A + D +  L  ++    ELEK +RR D E S+  E+   ++ + E+L+ +   
Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490

Query: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205
               E  +   + E++    A   + +   +A L +       +  +  K +KQ RDL  +
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550

Query: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
            ++    EL++   +    ++ + + E E+  +++T  +E    +  V+E RQ   + L +
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ 1610

Query: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1325
            +  QLE+    K    + +  LE +++ L     S Q  R++ E   +RL   L+  +  
Sbjct: 1611 MEVQLEEEYEDKQKVLREKRELEGKLATL-----SDQVNRRDFES-EKRLRKDLKRTKAL 1664

Query: 1326 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEE 1385
              D +    +  +    ++ E+  +   L E+E       K   + E ++ D    + + 
Sbjct: 1665 LADAQ-LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723

Query: 1386 TRAKLALGSRVRAMEAEAAGLREQLEEE-----------AAARERAGREL---QTAQAQL 1431
             +AK AL  ++  ++ E   ++ +LEE+            AA  +A R+L      QAQL
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1783

Query: 1432 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
             E  + ++E    L+A +        + E L Q + +K+  V R E   R L+  L+   
Sbjct: 1784 EEANKEKQELQEKLQALQS-------QVEFLEQSMVDKS-LVSRQEAKIRELETRLEFER 1835

Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALE 1551
              +++   L S L++   K  +   +  AA  R  E+ +R + + R+ +     L R   
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA 1895

Query: 1552 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELED 1611
            E    + ELE    +L A  ++L +      K + +L+ A  + ++  +D    +   E 
Sbjct: 1896 EASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAA--IEDEMESDENEDLINSEG 1953

Query: 1612 ELTAAEDAKLRLEVTVQALKT 1632
            +     D    LE  V  +K+
Sbjct: 1954 D----SDVDSELEDRVDGVKS 1970



 Score =  192 bits (489), Expect = 2e-48
 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)

Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
            R  +E+QL E Q R  D E  +  +  KL++A+ E   +    +  ES+   L+ EL+  
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301

Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1411
                  A +LL  ET  +L     ++ ++ +   L++Q+E                    
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361

Query: 1412 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468
               ++A    R   E    +   ++ R +QE E   LE  ++ +R+  R    L     E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420

Query: 1469 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
                + +L++  +RL  EL D  + LE Q+     LEKKQR+FD  L++      R   +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480

Query: 1529 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588
            RE+ + E     A A SL + LEE+        ++  +L AEL+ + S +     S+ ++
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540

Query: 1589 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648
            ++  R  E    D   ++ E    +   E AKLRLE+ ++ ++  H ++++ RDE  EE 
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600

Query: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
            R+   K+L+  EV+ +EE + +   +  +++LEG+L  L  Q+    +   E+ K+LRK 
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657

Query: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1768
              + K L  + +       +    +  S++ +  L+ ++   +   AA+ +AR+  + + 
Sbjct: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713

Query: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1828
            +++  ++ +   +K A+ E+  +L+    +++  LEE+Q +   L  +++  + Q     
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773

Query: 1829 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1888
             +++  ++   +A   +Q+L+ ++Q L+ ++  E        K  ++  E+K+ + E +L
Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831

Query: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1946
            E E  +     K +     RLKE + ++ EER  R+A + R++ +      K+L+RQL +
Sbjct: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882

Query: 1947 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1979
             +E   E +R +A   R + ELE   ES E+ N+ +
Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918



 Score =  156 bits (394), Expect = 2e-37
 Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)

Query: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
            +EQ+  + +  ++LR++L + E+E       ++      ++L   L + +     A + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312

Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1227
            ++E   R +AEK+ ++L  + +AL+ ++E                    +D  +A  E R
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372

Query: 1228 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
             K E+ V E+   KK L++E        Q+ +++  + LG+L    E+++R     +K  
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432

Query: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344
              L AE+ + +  L   Q    E E+++RR + +L +    A           EKLQR  
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482

Query: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
                              +L +E     A+    ++ L+E+         +V ++EAE  
Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524

Query: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1464
             +  Q  ++ A+  +  ++L+  +A++ +     +E+AG ++  E+A+ R   E E + Q
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584

Query: 1465 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
              +++ E+ D  +E  R+  Q++L    + LE++                   E+K  VL
Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626

Query: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1576
            R     E+ E EG+          R  E E+  R++L+R  +AL A+ + +L        
Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680

Query: 1577 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1626
            SK ++ +  ++LE          +A +  E    DL  Q+ ++    TA E+   RL+  
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740

Query: 1627 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1680
               ++ + E D +  +E  ++ +  +A+      Q+ D + + +E  K++       + L
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800

Query: 1681 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1724
            + ++E L+  M       ++EA               VK+L  + +++KE   ++ E R 
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860

Query: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
             R  I ++NRE E+  K L+ ++   +EE+    R   +A + + E+  ++ +   +  +
Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917

Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSE 1811
            +  + +    R+G L+  +E+E  + E
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944



 Score =  116 bits (291), Expect = 2e-25
 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)

Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
            V   E++ R  D+ + + ++ + +A +ER          E+R   LT  L +E+   E  
Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308

Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1616
             +   A  AE         ++      L++   V E    + R    A++    D+  A 
Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368

Query: 1617 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
             + +L+ E  V+ +   K + +++ + + E  ++ +RQL ++L D  ++ D E  QR L 
Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426

Query: 1674 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1731
               +K  +L  EL++ K  +        E  K+ R+  +++ +   E +  +  RE++  
Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484

Query: 1732 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1784
              RE +  L    AE   L+++L   D       +     + +  +++ + +    S A 
Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539

Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1843
            + ++ R LE ++   EEEL+E+    ++L     +L +++E +    S E  S   + E 
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599

Query: 1844 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
             RQ  +++++++  +L EE  D     R K     LE KLA   +Q+ +   E   S K 
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653

Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
            +R+  KR K ++   +    + D L++        + QLK QLEE+E   + A   R+ +
Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709

Query: 1962 QRELEDVTESAESMNREVTTLRNRLRR 1988
            + E+ED+    + + +  T L  +L R
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736



 Score =  109 bits (272), Expect = 3e-23
 Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%)

Query: 1428 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1481
            + QLSE + R ++E        LE  E+ R      ++ L  R++E T E  D    G  
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307

Query: 1482 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1537
              Q       +D E   +L +  E K  Q ++D L  + +   +  +E R    AE  G 
Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361

Query: 1538 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1581
                          ER  R +  T+  L++E E + E+E+QN R L   L  L +  ++ 
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421

Query: 1582 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1641
             +++ +L++ C+       D +  +   +      E  + R +  +     + +R+   R
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481

Query: 1642 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1699
            ++   E+   LA+      +++  E K   +A   +K   LE EL+++ +Q +       
Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538

Query: 1700 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1756
            +  KQLR ++A++K+   E++E   + + +       E   +R++   ++ +  ++E   
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597

Query: 1757 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1816
             + AR+  Q+   +M  ++      K  +L EKR+LEG+L  L +++      SE    R
Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653

Query: 1817 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1876
             RK L + ++L  +          +   +    R+I +L+ +L E +         T AA
Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701

Query: 1877 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1936
                  +A + +E E  +  L    + +A+  L+E + +++ E+   ++++++LE+    
Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754

Query: 1937 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
            + +L ++ + A  +ASR  A    LQ +LE+  +  + +  ++  L++++
Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%)

Query: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1776
            R + E + S E+I +++ E ++    LE       E    SDR   +  +   E+ DE  
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303

Query: 1777 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1836
             G  S + +L+          +  E L  E+   E L  +Y  L  Q+E +  E+   R 
Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352

Query: 1837 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1896
              A              E+ G + ++DAG   R K   A  E      +++L+QE  +++
Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397

Query: 1897 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1941
             +  +  R+ E+RL ++    EE +R   QL+ +              LE   +R  +L+
Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457

Query: 1942 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1994
            +       +L +A EEA R +  R +LQRE + +   A S+ +++      +      FT
Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513

Query: 1995 TRTVRQVFRLEEGVASDEEAEEA 2017
             + V     L++ ++S E  +EA
Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  464 bits (1195), Expect = e-130
 Identities = 322/977 (32%), Positives = 514/977 (52%), Gaps = 94/977 (9%)

Query: 91   LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ 150
            +   ++  M+P      +DMA LT L+  S+++NL +RY    IYTY G     +NPY+ 
Sbjct: 49   ITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQP 108

Query: 151  LP-IYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTK 209
            +  +Y  A +E Y  +   E+PPH++A+    YR + +  ++Q IL +GESGAGKTE+TK
Sbjct: 109  IAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTK 168

Query: 210  KVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSR 269
             ++++L+ ++       E  +    S V     ER +L+++PI+EAFGNAKTV N+NSSR
Sbjct: 169  LILKFLSVISQQSL---ELSLKEKTSCV-----ERAILESSPIMEAFGNAKTVYNNNSSR 220

Query: 270  FGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLL 329
            FGKF+++N    G I G  I  YLLEK+R +RQ   E ++HIFY LL G   + + +  L
Sbjct: 221  FGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYL 280

Query: 330  EPCSHYRFLTNG--PSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIA 387
                +Y +L            ++E F+E + ++ V+ FS EE+  + R+++ +L  GNI 
Sbjct: 281  STPENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE 340

Query: 388  LKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFA 447
                     A +   TA  +   LLGL  T  + AL    + +  + +      +QA  +
Sbjct: 341  F---ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDS 397

Query: 448  LEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTN 507
             ++LA A Y   F W++ ++N  +     +    +GILDI GFE F++N FEQ  INY N
Sbjct: 398  RDSLAMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYAN 455

Query: 508  EKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECW 567
            EKLQ+ FN  +F LEQ EY REG+ W  +D+ +D   C+DLIE+     GLLAL++EE  
Sbjct: 456  EKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESH 511

Query: 568  FPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLN 627
            FP+ATD + +EK+  +   +  + +PR   +  +F V HYAG+V Y     L KN D   
Sbjct: 512  FPQATDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFR 569

Query: 628  DNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVG 687
            D++  LL +S                 +F F+                       E +  
Sbjct: 570  DDLLNLLRES-----------------RFDFIYDL-------------------FEHVSS 593

Query: 688  LEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGK 747
                 +L  G    RP      TV   +K+SL  LMATLS++NP FVRCI PN +K   +
Sbjct: 594  RNNQDTLKCGSKHRRP------TVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQ 647

Query: 748  LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPN-AIPKGFMDGKQACE 806
             +  +VL+QLR +G+LE +RI + G+  R  FQ+F +RY++L  N A+P+   D +  C 
Sbjct: 648  FDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE---DVRGKCT 704

Query: 807  KMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQK 866
             ++Q  +   + +++G++K+F R  +  +LE+ R+ +V+   +  +A   G+LAR+ ++K
Sbjct: 705  SLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRK 764

Query: 867  RQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQ 926
                   + ++Q+N  A+L  R     R     K  +   +Q     AR    Q + E +
Sbjct: 765  ---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKR 816

Query: 927  QQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELE 986
            +Q  ++  E + +  + EEER R  E+ R EAEL A+ EE       RKQ+      ELE
Sbjct: 817  EQEEKKKQEEEEKKKREEEERER--ERERREAELRAQQEE-----ETRKQQ------ELE 863

Query: 987  ARVGEEEECSRQMQTEKKRLQQHIQE-LEAHLEAEEGARQKLQLEKVTTEAKMKKFEE-- 1043
            A    ++E     + EK++  + ++E L    E E+  R K Q E   TEA ++K +E  
Sbjct: 864  ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERR 923

Query: 1044 --DLLLLEDQNSKLSKE 1058
              +L  LE++  + ++E
Sbjct: 924  DQELRRLEEEACRAAQE 940



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 70/233 (30%), Positives = 113/233 (48%), Gaps = 31/233 (13%)

Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ-E 1439
            ++Q+  RA L L  R   ++  A   ++QL  + A   R  R+L  A+ +  E +++Q E
Sbjct: 771  IIQKNYRAFL-LRRRFLHLKKAAIVFQKQLRGQIA--RRVYRQL-LAEKREQEEKKKQEE 826

Query: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499
            EE    E  E  R R  REAE   Q+  E             R QQEL +A    +++ +
Sbjct: 827  EEKKKREEEERERERERREAELRAQQEEE------------TRKQQEL-EALQKSQKEAE 873

Query: 1500 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA-LEEEQEAR- 1557
            L   LEK++        ++   +LR  +E E  +   R +E + LSLT A L++ QE R 
Sbjct: 874  LTRELEKQKEN------KQVEEILRLEKEIEDLQ---RMKEQQELSLTEASLQKLQERRD 924

Query: 1558 EELER-QNRALRAELEALLS-SKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
            +EL R +  A RA  E L S + D++ + V  +ER+  V  + +++L     E
Sbjct: 925  QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACE 977



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 12/148 (8%)

Query: 1025 QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1084
            ++L  EK   E K K+ EE+    E++  +  +ER     R AE  +Q  EE  K + L 
Sbjct: 809  RQLLAEKREQEEKKKQEEEEKKKREEEERERERER-----REAELRAQQEEETRKQQELE 863

Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1144
             L+   +   A++   L K+++ +Q  E L  RL+ E  +LQ   +++QQ      A L 
Sbjct: 864  ALQKSQKE--AELTRELEKQKENKQVEEIL--RLEKEIEDLQR--MKEQQELSLTEASLQ 917

Query: 1145 RKEEELQAALARAEDEGGARAQ-LLKSL 1171
            + +E     L R E+E    AQ  L+SL
Sbjct: 918  KLQERRDQELRRLEEEACRAAQEFLESL 945



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 36/141 (25%), Positives = 74/141 (52%), Gaps = 12/141 (8%)

Query: 1137 EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAE 1196
            ++LR Q+ R+      A  R ++E   + +  K  RE +    E +E  E+E  A+ + E
Sbjct: 797  KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE-RERREAELRAQQEEE 855

Query: 1197 KQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE--------EETRIH 1248
             +++   +ELEAL+   ++   +   +++  +K+ +E+  L+K +E        +E  + 
Sbjct: 856  TRKQ---QELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLT 912

Query: 1249 EAAVQELRQRHGQALGELAEQ 1269
            EA++Q+L++R  Q L  L E+
Sbjct: 913  EASLQKLQERRDQELRRLEEE 933



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 20/156 (12%)

Query: 1805 EEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDA 1864
            ++Q   ++    YR+LL +      +   E     K E   ++ ER+ +E   R  +E+ 
Sbjct: 796  QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEE- 854

Query: 1865 GARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE----R 1920
                         E++  Q  E L++  +E  L+ +L ++ E +  E +L++E+E    +
Sbjct: 855  -------------ETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ 901

Query: 1921 RVADQLRDQLEKGNLRVKQLKR--QLEEAEEEASRA 1954
            R+ +Q    L + +L+  Q +R  +L   EEEA RA
Sbjct: 902  RMKEQQELSLTEASLQKLQERRDQELRRLEEEACRA 937



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 41/177 (23%), Positives = 79/177 (44%), Gaps = 14/177 (7%)

Query: 1087 RLKYEATIADMEDRLRK-----EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1141
            R  Y   +A+  ++  K     EEK ++E E+ +R  +   +EL+ Q  E+ ++ +EL A
Sbjct: 805  RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA 864

Query: 1142 -QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
             Q  +KE EL   L + ++      + ++ +   +  + + Q   E + ++ T+A  Q+ 
Sbjct: 865  LQKSQKEAELTRELEKQKEN-----KQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL 919

Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257
                + E  R E E       AQ+ L S    E+ E  + +E    +      EL +
Sbjct: 920  QERRDQELRRLEEE---ACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 54/182 (29%), Positives = 90/182 (49%), Gaps = 38/182 (20%)

Query: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG---RKEEELQAA 1153
            + ++  +EEK +QE E+ K+R      E +E+  E+++R  ELRAQ     RK++EL+A 
Sbjct: 812  LAEKREQEEKKKQEEEEKKKR------EEEERERERERREAELRAQQEEETRKQQELEA- 864

Query: 1154 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEAL-RGE 1212
                         L KS +EA     E   +LE ++  +   E  R  L +E+E L R +
Sbjct: 865  -------------LQKSQKEA-----ELTRELEKQKENKQVEEILR--LEKEIEDLQRMK 904

Query: 1213 LEDTLDSTNAQ-QELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE 1271
             +  L  T A  Q+L+ +R+QE+    + LEEE     AA + L   +   + E    +E
Sbjct: 905  EQQELSLTEASLQKLQERRDQEL----RRLEEEA--CRAAQEFLESLNFDEIDECVRNIE 958

Query: 1272 QA 1273
            ++
Sbjct: 959  RS 960



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%)

Query: 1593 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ- 1651
            ++A +    L A+  E E++    E+ K + E   +  + +  R+ + R +  EE R+Q 
Sbjct: 802  QIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQ 860

Query: 1652 ----LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1707
                L K  ++AE+ R+ E+++    V    +LE E+E+L+           EA   L+K
Sbjct: 861  ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA--SLQK 918

Query: 1708 MQAQMKELWREVEE--TRTSREEIFSQN 1733
            +Q +  +  R +EE   R ++E + S N
Sbjct: 919  LQERRDQELRRLEEEACRAAQEFLESLN 946



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 19/139 (13%)

Query: 1178 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1237
            LAE +E  + E+  + + EK++R+  EE E  R   E  L    AQQE  ++++QE+  L
Sbjct: 812  LAEKRE--QEEKKKQEEEEKKKRE-EEERERERERREAEL---RAQQEEETRKQQELEAL 865

Query: 1238 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1297
            +K+ +E     E   Q+  ++  + L  L +++E  +R K            E  EL   
Sbjct: 866  QKSQKEAELTRELEKQKENKQVEEIL-RLEKEIEDLQRMK------------EQQELSLT 912

Query: 1298 LSSLQTARQEGEQRRRRLE 1316
             +SLQ  ++  +Q  RRLE
Sbjct: 913  EASLQKLQERRDQELRRLE 931



 Score = 40.4 bits (93), Expect = 0.018
 Identities = 64/262 (24%), Positives = 113/262 (43%), Gaps = 26/262 (9%)

Query: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660
            D+R + T L  +L  A +++ +L  T   L+   E+ L+ R E        + +      
Sbjct: 698  DVRGKCTSLL-QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756

Query: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720
            + R + RK     V  +K     L  L+ +     +      KQLR   A          
Sbjct: 757  LARKQYRKVLYCVVIIQKNYRAFL--LRRRFLHLKKAAIVFQKQLRGQIA---------- 804

Query: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780
              R    ++ ++ RE E++ K  E E  + +EE    +R RR+A+  R +  +E      
Sbjct: 805  --RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAEL-RAQQEEETRKQQE 861

Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840
             +A    +K Q E    +L  ELE+++ N ++  +   +L  ++E L   +  ++  S  
Sbjct: 862  LEAL---QKSQKE---AELTRELEKQKENKQV--EEILRLEKEIEDL-QRMKEQQELSLT 912

Query: 1841 AESGRQQLERQIQELRGRLGEE 1862
              S ++  ER+ QELR RL EE
Sbjct: 913  EASLQKLQERRDQELR-RLEEE 933



 Score = 38.9 bits (89), Expect = 0.052
 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 11/138 (7%)

Query: 1059 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY-EATIADMEDRLRKEEKGRQELEKL-KR 1116
            R+LL ++  +   +  EEEEK K   + R +  E   A++  +  +E + +QELE L K 
Sbjct: 809  RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS 868

Query: 1117 RLDGESSELQEQMVEQQQRAEELR-------AQLGRKEEELQAALARAEDEGGARAQLLK 1169
            + + E +   E+  E +Q  E LR        Q  ++++EL    A  +     R Q L+
Sbjct: 869  QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELR 928

Query: 1170 SLREAQAALAEAQEDLES 1187
             L E   A   AQE LES
Sbjct: 929  RLEE--EACRAAQEFLES 944



 Score = 38.1 bits (87), Expect = 0.088
 Identities = 33/128 (25%), Positives = 66/128 (51%), Gaps = 12/128 (9%)

Query: 1853 QELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEV 1912
            ++LRG++      AR  ++  +A  E +  + +++ E+E +++    +  R  E+R  E+
Sbjct: 797  KQLRGQI------ARRVYRQLLA--EKREQEEKKKQEEEEKKKREEEERERERERREAEL 848

Query: 1913 VLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESA 1972
              Q EEE R   +L + L+K   +  +L R+LE+ +E     +    RL++E+ED+    
Sbjct: 849  RAQQEEETRKQQEL-EALQKSQ-KEAELTRELEKQKENKQVEEI--LRLEKEIEDLQRMK 904

Query: 1973 ESMNREVT 1980
            E     +T
Sbjct: 905  EQQELSLT 912



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 10/146 (6%)

Query: 1247 IHEAAVQELRQRHGQALGE-----LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL 1301
            + +AA+   +Q  GQ         LAE+ EQ  + K   E+ +   E E    R    + 
Sbjct: 788  LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847

Query: 1302 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1361
              A+QE E R+++   +L+ +Q    + E  R    +K  +   E+  +   + + +   
Sbjct: 848  LRAQQEEETRKQQ---ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--R 902

Query: 1362 IRLSKELSSTEAQLHDAQELLQEETR 1387
            ++  +ELS TEA L   QE   +E R
Sbjct: 903  MKEQQELSLTEASLQKLQERRDQELR 928



 Score = 37.0 bits (84), Expect = 0.20
 Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 30/157 (19%)

Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1431
            E +  + ++  +EE + K     R R  E   A LR Q EEE                  
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET----------------- 856

Query: 1432 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
                R+Q+E    LEA +++++ A    E   Q+  ++ E + RLE+    LQ+  +   
Sbjct: 857  ----RKQQE----LEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE 908

Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
            + L +     ++L+K Q + DQ L   +    RA +E
Sbjct: 909  LSLTE-----ASLQKLQERRDQELRRLEEEACRAAQE 940



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 4/122 (3%)

Query: 1901 LVRRAEKRLKE--VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1958
            L+RR    LK+  +V Q +   ++A ++  QL       ++ K+Q EE +++    +  R
Sbjct: 780  LLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER 839

Query: 1959 RRLQRELEDVTESAESMNR--EVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
             R +RE E   +  E   +  E+  L+   +   LT      ++  ++EE +  ++E E+
Sbjct: 840  ERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIED 899

Query: 2017 AQ 2018
             Q
Sbjct: 900  LQ 901



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 24/125 (19%), Positives = 58/125 (46%), Gaps = 13/125 (10%)

Query: 1894 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1953
            ++ L G++ RR  ++L     + EE+++   Q  ++ +K     ++ +R+  EAE  A +
Sbjct: 796  QKQLRGQIARRVYRQLLAEKREQEEKKK---QEEEEKKKREEEERERERERREAELRAQQ 852

Query: 1954 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 2013
             +  R++ + E    ++    + RE+   +            + V ++ RLE+ +   + 
Sbjct: 853  EEETRKQQELEALQKSQKEAELTRELEKQKE----------NKQVEEILRLEKEIEDLQR 902

Query: 2014 AEEAQ 2018
             +E Q
Sbjct: 903  MKEQQ 907


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  449 bits (1156), Expect = e-125
 Identities = 310/984 (31%), Positives = 496/984 (50%), Gaps = 114/984 (11%)

Query: 99   MNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAI 158
            M+P      +DM  L  LNEA ++HNL  RY    IYTY+G   V +NP++ LP+YT   
Sbjct: 59   MHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQ 118

Query: 159  VEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHV 218
            V++Y  +   E+PPHV+A+    Y SM +++ DQ  + +GESGAGKTE TK ++Q+LA +
Sbjct: 119  VQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATI 178

Query: 219  ASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 278
            +                   +  +E+Q+L+ANPILEAFGNAKT++NDNSSRFGK+I I F
Sbjct: 179  SGQ-----------------HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYF 221

Query: 279  DVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFL 338
            + +G I GA IE +LLEKSR  RQA +E ++HIFY +L G   + K  L L   S Y +L
Sbjct: 222  NPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYL 281

Query: 339  TNGPSSSPG--QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRE--RNT 394
            T G  +S     + + +     ++++L FS  E   ++++++A+L  GN+        N 
Sbjct: 282  TMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENL 341

Query: 395  DQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKA 454
            D + + +  A   + +LL +   +    L+   I +  ++V ++    QA    +A  K 
Sbjct: 342  DASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKG 401

Query: 455  TYERLFRWLVLRLNRALDRSPRQGAS----FLGILDIAGFEIFQLNSFEQLCINYTNEKL 510
             Y  LF W+V ++N A+   P Q        +G+LDI GFE F+ NSFEQLCIN+ NE L
Sbjct: 402  IYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHL 461

Query: 511  QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK 570
            QQ F   +F +EQEEY+ E I W ++ +  D +P +DL+     P  +++LLDEE  FP+
Sbjct: 462  QQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTLDLL--ALKPMSIISLLDEESRFPQ 518

Query: 571  ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV 630
             TD + ++K+      +  F +P+++ D A F + H+AG+V Y+A  +L KN D L+ ++
Sbjct: 519  GTDLTMLQKLNSVHANNKAFLQPKNIHD-ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDI 577

Query: 631  AALLHQSTDRLTAEIWKDE-------HGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVE 683
              L++ S ++   EI+  E       HG  +Q +  G+       S +R S         
Sbjct: 578  LTLVYSSKNKFLREIFNLELAETKLGHGTIRQ-AKAGNHLFKSADSNKRPS--------- 627

Query: 684  GIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEK 743
                                      T+G  +K+SL +LM  L+N  P F+RCI PN  K
Sbjct: 628  --------------------------TLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYK 661

Query: 744  RAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQ 803
            +    +  L L QLR +G++E + I + GFP R  F+EF QR+ +L PNA+        +
Sbjct: 662  KPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLR 721

Query: 804  ACEKMIQALELDPNL-YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARR 862
                 I  + L  +  ++ G++KIF R      LE +R   +    +S Q   RGY  R+
Sbjct: 722  QMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRK 781

Query: 863  AFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRL-FTKVKPLLQ---VTRQDEVLQARAQE 918
             F ++++    L+   R    Y   R+++   + F +++ + +   + RQ + ++ R  +
Sbjct: 782  EFLRQRRAAVTLQAWWR---GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQ 838

Query: 919  LQK------VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLA 972
            LQ       V++  Q   R V  +Q     +   R     +  A   + AE ++++G L 
Sbjct: 839  LQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALP 898

Query: 973  ARKQE-----------LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 1021
            A+K+            +E V   L A +G +E                  +   H E  E
Sbjct: 899  AKKRRSIYDTVTDTEMVEKVFGFLPAMIGGQE-----------------GQASPHFEDLE 941

Query: 1022 GARQKLQLEKVTTEAKMKKFEEDL 1045
               QKL    + T    ++ EED+
Sbjct: 942  SKTQKLLEVDLDTVPMAEEPEEDV 965


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  449 bits (1154), Expect = e-125
 Identities = 302/868 (34%), Positives = 448/868 (51%), Gaps = 90/868 (10%)

Query: 108  EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
            EDM +L  L E +VL NL+ R+   LIYTY G   V +NPY+   IY    V+ Y G+  
Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284

Query: 168  HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
             E PPH++AV   A+  ML  +++Q I+ +GESG+GKTE TK +++YLA +    +  + 
Sbjct: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343

Query: 228  PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
                           + ++L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F   G I GA
Sbjct: 1344 ---------------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGA 1387

Query: 288  NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--S 345
                YLLEKSR + QAK+E ++HIFY+LL G   QL+    L+    Y +L  G +   +
Sbjct: 1388 ITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIA 1447

Query: 346  PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQ--ATMPDNT 403
               + + F+  L ++ VLGFS E+  S+ R+++++L  GN+  ++     Q  A++    
Sbjct: 1448 GKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAR 1507

Query: 404  AAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWL 463
              Q +  LL +      +A+     +  R+ +    T E A  A +A+AK  Y  LF WL
Sbjct: 1508 EIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWL 1567

Query: 464  VLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
            + R+N  +  SPRQ    + ILDI GFE    NSFEQLCINY NE LQ LFN  +F  EQ
Sbjct: 1568 ITRVNALV--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQ 1625

Query: 524  EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE 583
            EEY RE I W  + F  D QPCI+LI     P G+L +LD++C FP+ATD +F++K    
Sbjct: 1626 EEYIREQIDWQEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYH 1682

Query: 584  QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
             G +P + +P+      +F++ HYAGKV Y+ +++L KN D +  +V  L  +S  R+ A
Sbjct: 1683 HGANPLYSKPK--MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740

Query: 644  EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
             +            F    P + P    + SS                            
Sbjct: 1741 HL------------FSSHAPQAAPQRLGKSSSV--------------------------T 1762

Query: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
            R     TV   +++SL  L+  +   NP F+RC+ PNH+K  G  EP +V+ QLR +GVL
Sbjct: 1763 RLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVL 1822

Query: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQAL-ELDPNLYRVG 822
            E +RI ++GFP R+ FQ F  RY  L   A+          C  ++  L ++ PN+YRVG
Sbjct: 1823 ETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKHDLPANGDMCVSVLSRLCKVMPNMYRVG 1880

Query: 823  QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
             SK+F +  +   LE  R+  +    ++ Q   RG+  +R F+  + +   + ++Q    
Sbjct: 1881 VSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHK---IILLQSRAR 1937

Query: 883  AYL-KLRHWQWWRLFTKVKPLLQV---------TRQDEVLQARAQELQKVQELQQQSARE 932
             YL + R+ Q  R   K + L+            R +   Q     L + +EL ++    
Sbjct: 1938 GYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVEGALLWEQEELSKREVVA 1997

Query: 933  VGELQGRVAQLEEERARLAEQLRAEAEL 960
            VG L        E  A LA  L+A A L
Sbjct: 1998 VGHL--------EVPAELAGLLQAVAGL 2017


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  441 bits (1135), Expect = e-123
 Identities = 290/790 (36%), Positives = 417/790 (52%), Gaps = 82/790 (10%)

Query: 109 DMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRH 168
           DM  L  LNE + ++NL++R+    IYTY G   + +NPY+ LPIY+   VE YR +  +
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 169 EVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEP 228
           E+ PH++A+++ AYRS+    +DQ IL TGESGAGKTE +K V+ Y+A V          
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC--------- 129

Query: 229 GVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGAN 288
           G  A V+ V     + QLLQ+NP+LEAFGNAKTV+NDNSSRFGK++ I FD  G  +G  
Sbjct: 130 GKGAEVNQV-----KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGV 184

Query: 289 IETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE-PCSHYRFLTNGPSSSPG 347
           I  YLLEKSR ++Q + E +FH+FYQLL GA E+L   L LE   S Y +L+   +   G
Sbjct: 185 ISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNG 244

Query: 348 -QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNT---DQATMPDNT 403
             +   F+    +++++GF   E  S+L +V+AVL+ GNI  K E      D++ + D  
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304

Query: 404 AAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWL 463
             +++C L G+  +   RA     ++  ++ V       QA +A +ALAK  Y RLF WL
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364

Query: 464 VLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
           V R+N ++    +     +G+LDI GFEIF+ NSFEQ  INY NEKLQQ+F       EQ
Sbjct: 365 VNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQ 424

Query: 524 EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFP-KATDKSFVEKVAQ 582
           EEY RE I WT +D+  +   C DLIE   N  G+LA+LDEEC  P   TD++F+EK+ Q
Sbjct: 425 EEYIREDIEWTHIDYFNNAIIC-DLIENNTN--GILAMLDEECLRPGTVTDETFLEKLNQ 481

Query: 583 EQGGHPKFQR-----PRHLRD----QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAAL 633
               H  F+       R L D     + F + HYAGKV Y+   ++ KN D        L
Sbjct: 482 VCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNND--------L 533

Query: 634 LHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSS 693
           L++    L+  +WK  H                         ++ P G    + L++   
Sbjct: 534 LYRD---LSQAMWKASHA---------------------LIKSLFPEGNPAKINLKR--- 566

Query: 694 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 753
               PP          T G  +K S++ LM  L   NP+++RCI PN +K A      LV
Sbjct: 567 ----PP----------TAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALV 612

Query: 754 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 813
             Q+R  G+LE +R+ R G+  R  ++   +RY++L     P      +   E +   LE
Sbjct: 613 CHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE 672

Query: 814 LDPNLYRVGQSKIFFR-AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQS 872
           +    Y  G+SKIF R    L +LE+ R  ++ D+    Q   RG+  R  F   ++ Q 
Sbjct: 673 IPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQI 732

Query: 873 ALRVMQRNCA 882
            +    R  A
Sbjct: 733 VIAAWYRRYA 742


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,145,202
Number of Sequences: 37866
Number of extensions: 3667588
Number of successful extensions: 78983
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 774
Number of HSP's successfully gapped in prelim test: 1672
Number of HSP's that attempted gapping in prelim test: 19707
Number of HSP's gapped (non-prelim): 18964
length of query: 2036
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1918
effective length of database: 13,779,330
effective search space: 26428754940
effective search space used: 26428754940
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press