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Search of human proteins with 224831241
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
(2036 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 3918 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 3831 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 3810 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 2588 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 2519 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 2446 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 2441 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 2440 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 2435 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 1306 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 1295 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1293 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1293 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 1291 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 1288 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 1288 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 1285 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 1276 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 1245 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 1141 0.0
gi|122937345 myosin VB [Homo sapiens] 554 e-157
gi|153945715 myosin VC [Homo sapiens] 549 e-156
gi|215982794 myosin VA isoform 2 [Homo sapiens] 536 e-152
gi|215982791 myosin VA isoform 1 [Homo sapiens] 534 e-151
gi|28416946 myosin 18A isoform a [Homo sapiens] 531 e-150
gi|42794779 myosin 18A isoform b [Homo sapiens] 526 e-149
gi|154354979 myosin X [Homo sapiens] 464 e-130
gi|122937512 myosin VIIB [Homo sapiens] 449 e-125
gi|118402590 myosin XV [Homo sapiens] 449 e-125
gi|194328685 myosin IB isoform 1 [Homo sapiens] 441 e-123
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 3918 bits (10161), Expect = 0.0
Identities = 2036/2036 (100%), Positives = 2036/2036 (100%)
Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
Query: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
Query: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
Query: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
Query: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
Query: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
Query: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
Query: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
Sbjct: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
Query: 661 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 661 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
Query: 721 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 721 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
Query: 781 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 781 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
Query: 841 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 841 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
Query: 901 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 901 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
Query: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
Query: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
Query: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
Query: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
Query: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
Query: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
Query: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
Query: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
Query: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
Query: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
Query: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
Query: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
Query: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 3831 bits (9935), Expect = 0.0
Identities = 2003/2036 (98%), Positives = 2003/2036 (98%), Gaps = 33/2036 (1%)
Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
Query: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
Query: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
Query: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
Query: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
Query: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
Query: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
Query: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD
Sbjct: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------ 648
Query: 661 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 649 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 687
Query: 721 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 688 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 747
Query: 781 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 748 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 807
Query: 841 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 808 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 867
Query: 901 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 868 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 927
Query: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 928 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 987
Query: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 988 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1047
Query: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1048 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1107
Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1108 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1167
Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1168 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1227
Query: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1228 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1287
Query: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1288 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1347
Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1348 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1407
Query: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1408 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1467
Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527
Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1587
Query: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1588 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1647
Query: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1648 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1707
Query: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1708 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1767
Query: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1768 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1827
Query: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1828 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1887
Query: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1888 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1947
Query: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1948 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2003
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 3810 bits (9880), Expect = 0.0
Identities = 1995/2036 (97%), Positives = 1995/2036 (97%), Gaps = 41/2036 (2%)
Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP G
Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G 232
Query: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 233 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292
Query: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 293 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 352
Query: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412
Query: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 472
Query: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 473 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 532
Query: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 533 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 592
Query: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD
Sbjct: 593 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------ 640
Query: 661 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 641 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 679
Query: 721 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 680 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 739
Query: 781 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 740 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 799
Query: 841 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 800 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 859
Query: 901 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 860 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 919
Query: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 920 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 979
Query: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 980 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1039
Query: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1040 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1099
Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1100 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1159
Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1160 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1219
Query: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1220 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1279
Query: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1280 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1339
Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1340 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1399
Query: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1400 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1459
Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519
Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1579
Query: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1580 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1639
Query: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1640 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1699
Query: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1700 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1759
Query: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1760 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1819
Query: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1820 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1879
Query: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1880 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1939
Query: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1940 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 1995
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 2588 bits (6707), Expect = 0.0
Identities = 1312/1989 (65%), Positives = 1622/1989 (81%), Gaps = 48/1989 (2%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +WTA++LVW+PSE HGFEAA++++E +E VELAE+G++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK
Sbjct: 87 VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK
Sbjct: 147 RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ +P GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DHNIP--------GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE ++YRFL+NG P
Sbjct: 259 ANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIP 318
Query: 347 GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
GQ+ ++ FQET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT A
Sbjct: 319 GQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVA 378
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QKLC LLG+ V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV
Sbjct: 379 QKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVH 438
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALDR+ RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439 RINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG
Sbjct: 499 YQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQG 558
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
H KFQ+PR L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR AE+
Sbjct: 559 SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGG--RP 703
WKD V+ IVGL+QV+ + + G +
Sbjct: 619 WKD---------------------------------VDRIVGLDQVTGMTETAFGSAYKT 645
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
++GMFRTVGQLYKESL++LMATL NTNP+FVRCI+PNHEKRAGKL+P LVLDQLRCNGVL
Sbjct: 646 KKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVL 705
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
EGIRICRQGFPNRI+FQEFRQRYEILTPNAIPKGFMDGKQACE+MI+ALELDPNLYR+GQ
Sbjct: 706 EGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765
Query: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
SKIFFRAGVLA LEEERDLK+TDII+ FQA RGYLAR+AF K+QQQ SAL+V+QRNCAA
Sbjct: 766 SKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAA 825
Query: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
YLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+ +EL KV+E Q + E+ E++ + QL
Sbjct: 826 YLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQL 885
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
EE+ LAEQL+AE EL AEAEE R RLAA+KQELE ++ +LE+RV EEEE ++ +Q EK
Sbjct: 886 LEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEK 945
Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
K++Q HIQ+LE L+ EEGARQKLQLEKVT EAK+KK EE++LLLEDQNSK KE+KL+E
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
DR+AE SSQ AEEEEK K+L K+R K E I+D+E+RL+KEEK RQELEK KR+LDGE++
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT 1065
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
+LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR +DE + LK +RE QA +AE QE
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
D ESE+ +R KAEKQ+RDL EELEAL+ ELEDTLD+T AQQELR+KREQEV ELKK LEE
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
ET+ HEA +Q++RQRH AL EL+EQLEQA+R K EK + LE + EL E+ LQ
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
+ E E +R++L+ Q+QE+ + +G+R R E AEK + Q EL+NVS L EAE K I+
Sbjct: 1246 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1305
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
+K+ +S E+QL D QELLQEETR KL L SR+R +E E L+EQ EEE AR+ ++
Sbjct: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
+ Q+QL++ +++ +++ G +E+ EEA+++ ++AEAL+QRL EK D+LE+ + RL
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
QQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLAEEK+ R EER+RAEAE RE+E +A
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
LSL RALEE EA+EE ERQN+ LRA++E L+SSKDDVGK+VHELE++ R EQ ++R
Sbjct: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQ RDE EE++R L KQ+R+ E E
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 1605
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
++ERKQR LAVA++KK+E +L++L+AQ+ +A + ++E +KQLRK+QAQMK+ RE+EE R
Sbjct: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+S+RARR A+Q+RDE+ADE+ N K+
Sbjct: 1666 ASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKS 1725
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR+RK LQV++L EL+AERS + K+++
Sbjct: 1726 ALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDN 1785
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
RQQLERQ +EL+ +L E + +++ K TI+ALE+K+ Q EEQLEQE +ER + KLVR
Sbjct: 1786 ARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVR 1845
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
R EK+LKE+ +QVE+ERR ADQ ++Q+EK N R+KQLKRQLEEAEEEA+RA A RR+LQR
Sbjct: 1846 RTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905
Query: 1964 ELEDVTESAESMNREVTTLRNRLRR-GPLTF-TTRTVRQVFRLEEG--VASDEEAEEAQP 2019
EL+D TE+ E ++REV+TL+NRLRR GP++F ++R+ R+ LE SD++ E
Sbjct: 1906 ELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTS 1965
Query: 2020 GSGPSPEPE 2028
+ P+
Sbjct: 1966 DVNETQPPQ 1974
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 2519 bits (6528), Expect = 0.0
Identities = 1267/1982 (63%), Positives = 1589/1982 (80%), Gaps = 49/1982 (2%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A++LVWVPS+ GFE A+L++E EEA VEL E+G+++++ +D IQ+MNPPKFSK
Sbjct: 23 QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK
Sbjct: 83 VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K
Sbjct: 143 RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ G ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 203 DQG-----------ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVG 251
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG + P
Sbjct: 252 ANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIP 311
Query: 347 GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
GQ+ +++FQET+E++R++G EE + +LR++S VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 312 GQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAA 371
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+ LLG+ VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVL
Sbjct: 372 QKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVL 431
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 432 RINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEE 491
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG
Sbjct: 492 YQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQG 551
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+ +E+
Sbjct: 552 THPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSEL 611
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
WKD V+ I+GL+QV+ + + P +
Sbjct: 612 WKD---------------------------------VDRIIGLDQVAGMSETALPGAFKT 638
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
R+GMFRTVGQLYKE L++LMATL NTNP+FVRCI+PNHEK+AGKL+P LVLDQLRCNGVL
Sbjct: 639 RKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVL 698
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
EGIRICRQGFPNR++FQEFRQRYEILTPN+IPKGFMDGKQAC MI+ALELD NLYR+GQ
Sbjct: 699 EGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQ 758
Query: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
SK+FFRAGVLA LEEERDLK+TD+I+ FQA RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 759 SKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAA 818
Query: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
YLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+ +EL KV+E Q + + E++ +QL
Sbjct: 819 YLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQL 878
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
E+ +L EQL+AE ELCAEAEE R RL A+KQELE + +LEARV EEEE + +Q EK
Sbjct: 879 MAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK 938
Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
K++QQ+IQELE LE EE ARQKLQLEKVTTEAK+KK EE+ ++LEDQN KL+KE+KLLE
Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
DR+AEF++ EEEEK KSL KL+ K+EA I D+E+RLR+EEK RQELEK +R+L+G+S+
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
+L +Q+ E Q + EL+ QL +KEEELQAALAR E+E + LK +RE ++ ++E QE
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
DLESER +R KAEKQ+RDLGEELEAL+ ELEDTLDST AQQELRSKREQEV LKKTLEE
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
E + HEA +QE+RQ+H QA+ ELAEQLEQ +R K EK + LE E EL E+ L
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
+ + E +R+++E QLQE+Q + +GER R E A+K+ + Q EL+NV+G L++++SK+ +
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
L+K+ S+ E+QL D QELLQEE R KL+L ++++ +E E REQLEEE A+ ++
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
+ T AQ+++ +++ E+ G LE EE +R+ ++ E L+QR EK D+LE+ + RL
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
QQELDD +DL+ QRQ LEKKQ+KFDQLLAEEK + EER+RAEAE RE+E +A
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
LSL RALEE E + ELER N+ R E+E L+SSKDDVGKSVHELE++ R EQ +++
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQGRDE EE+++QL +Q+R+ E E
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
++ERKQR++AVAARKKLE +L++L+A + SA + ++EA+KQLRK+QAQMK+ RE+++TR
Sbjct: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 1658
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
SREEI +Q +E+EK+LK +EAE+++LQEELAA++RA+RQAQQ+RDE+ADE+AN + A
Sbjct: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
LEEKR+LE R+ QLEEELEEEQ N+EL+NDR +K LQ++ + T+L+ ERS + K E+
Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
RQQLERQ +EL+ +L E + ++++K +I ALE+K+AQ EEQL+ ET+ER + K VR
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
R EK+LK+V+LQV++ERR A+Q +DQ +K + R+KQLKRQLEEAEEEA RA A RR+LQR
Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898
Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGP 2023
ELED TE+A++MNREV++L+N+LRRG L F R++ R G SDEE + G+
Sbjct: 1899 ELEDATETADAMNREVSSLKNKLRRGDLPFV--VPRRMARKGAGDGSDEEVDGKADGAEA 1956
Query: 2024 SP 2025
P
Sbjct: 1957 KP 1958
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 2446 bits (6339), Expect = 0.0
Identities = 1236/1974 (62%), Positives = 1576/1974 (79%), Gaps = 39/1974 (1%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + S +YGELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSITQGPS-FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 265
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 266 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 325
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 385
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 386 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 566 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
WKD V+ IVGL+Q++ + + P +
Sbjct: 626 WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 652
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+ LVL+QLRCNGVL
Sbjct: 653 KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 712
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
EGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQAC MI+ALELDPNLYR+GQ
Sbjct: 713 EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 772
Query: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
SKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 773 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 832
Query: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E QQ++ E+ EL+ + +QL
Sbjct: 833 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 892
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+ +Q+Q E+
Sbjct: 893 TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 952
Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 953 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + LK +RE + +++ QE
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQELR+KREQEVT LKK L+E
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + LE E ++L EL L
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
L+K+++S +QL D QELLQEETR KL + +++R +E E L++QL+EE A++ R
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
+ T QLS+ +++ ++ A +EA EE ++R +E E LTQ+ EK D+LE+ + RL
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
QQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + +ER+RAEAE RE+E +A
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
LSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R E +++
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE EE+RRQL +QL + E E
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQLRK+QAQMK+ RE+E+ R
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA +++E+A+E+A+ +
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q E L+ EL+ ERS + K ES
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ EEQ+EQE RE+ + K ++
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R A RR+LQR
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912
Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR--LEEGVASDEEAE 2015
EL++ TES E+M REV L+++LRRG T + R R +E S+EE +
Sbjct: 1913 ELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1966
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 2441 bits (6326), Expect = 0.0
Identities = 1228/1947 (63%), Positives = 1564/1947 (80%), Gaps = 37/1947 (1%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + S +YGELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSITQGPS-FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 265
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 266 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 325
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 385
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 386 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 566 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
WKD V+ IVGL+Q++ + + P +
Sbjct: 626 WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 652
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+ LVL+QLRCNGVL
Sbjct: 653 KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 712
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
EGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQAC MI+ALELDPNLYR+GQ
Sbjct: 713 EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 772
Query: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
SKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 773 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 832
Query: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E QQ++ E+ EL+ + +QL
Sbjct: 833 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 892
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+ +Q+Q E+
Sbjct: 893 TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 952
Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 953 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + LK +RE + +++ QE
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQELR+KREQEVT LKK L+E
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + LE E ++L EL L
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
L+K+++S +QL D QELLQEETR KL + +++R +E E L++QL+EE A++ R
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
+ T QLS+ +++ ++ A +EA EE ++R +E E LTQ+ EK D+LE+ + RL
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
QQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + +ER+RAEAE RE+E +A
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
LSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R E +++
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE EE+RRQL +QL + E E
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQLRK+QAQMK+ RE+E+ R
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA +++E+A+E+A+ +
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q E L+ EL+ ERS + K ES
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ EEQ+EQE RE+ + K ++
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R A RR+LQR
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912
Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGP 1990
EL++ TES E+M REV L+++LR P
Sbjct: 1913 ELDEATESNEAMGREVNALKSKLRGPP 1939
Score = 196 bits (499), Expect = 1e-49
Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%)
Query: 1142 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1194
Q+ R+EEE+QA L + ++ LK L + + L E QE L++E +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 1195 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1247
AE+ R ++L E L + LE+ D Q R K Q++ +L++ LEEE
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 969
Query: 1248 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
EAA Q+L+ A + +L +++ K R LE +S+L L+ +
Sbjct: 970 -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
+ + + + E + E++ R E++R E + ++ + + + + + +++ L
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088
Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
+L+ E +L A L +E K ++R +E + L+E L+ E AAR +A ++
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1483
+ +L + E+ + +E R + +E L + L E+T + + +++ R++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Q +++ T LEQ ++ + L+K ++ ++ A+ + + ++ E + ++ EA+
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1602
L + + AR EL + L+ E+E++ ++ GK++ + A D+
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1317
Query: 1603 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1660
+ ++L+D + E+ + +L V+ + + + ER+ LQ + + E ++ L + +
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 1661 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1713
++ D ++K + A +K+ + E+E L Q ++ K ++Q ++
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 1714 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1772
+L +++ R ++ S + +++ L AE + + A DRA +A++ ++ A
Sbjct: 1438 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1492
Query: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1825
+A L +A LE K +LE L+ E+E+ S N L R L Q+E
Sbjct: 1493 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549
Query: 1826 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1884
+ T+L E + +LE +Q L+G+ E D AR +++ L+ +L +
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1608
Query: 1885 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1944
E +LE E ++R L+ ++ E LK++ LQ + + ++ QL K ++K +R+L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668
Query: 1945 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1990
E+A E++A +A +LQ +L + + + E L L
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1727
Query: 1991 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 2021
L+ + RLE +A EE E + G+
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1758
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 2440 bits (6324), Expect = 0.0
Identities = 1234/1974 (62%), Positives = 1573/1974 (79%), Gaps = 46/1974 (2%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 259 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 319 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 379 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 499 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 559 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
WKD V+ IVGL+Q++ + + P +
Sbjct: 619 WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 645
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+ LVL+QLRCNGVL
Sbjct: 646 KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 705
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
EGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQAC MI+ALELDPNLYR+GQ
Sbjct: 706 EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 765
Query: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
SKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
Query: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E QQ++ E+ EL+ + +QL
Sbjct: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+ +Q+Q E+
Sbjct: 886 TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 945
Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + LK +RE + +++ QE
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQELR+KREQEVT LKK L+E
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + LE E ++L EL L
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
L+K+++S +QL D QELLQEETR KL + +++R +E E L++QL+EE A++ R
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
+ T QLS+ +++ ++ A +EA EE ++R +E E LTQ+ EK D+LE+ + RL
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
QQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + +ER+RAEAE RE+E +A
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
LSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R E +++
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE EE+RRQL +QL + E E
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQLRK+QAQMK+ RE+E+ R
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA +++E+A+E+A+ +
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q E L+ EL+ ERS + K ES
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ EEQ+EQE RE+ + K ++
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R A RR+LQR
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR--LEEGVASDEEAE 2015
EL++ TES E+M REV L+++LRRG T + R R +E S+EE +
Sbjct: 1906 ELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 2435 bits (6311), Expect = 0.0
Identities = 1226/1947 (62%), Positives = 1561/1947 (80%), Gaps = 44/1947 (2%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 259 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 319 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 379 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 499 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 559 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
WKD V+ IVGL+Q++ + + P +
Sbjct: 619 WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 645
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+ LVL+QLRCNGVL
Sbjct: 646 KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 705
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
EGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQAC MI+ALELDPNLYR+GQ
Sbjct: 706 EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 765
Query: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
SKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
Query: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E QQ++ E+ EL+ + +QL
Sbjct: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+ +Q+Q E+
Sbjct: 886 TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 945
Query: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + LK +RE + +++ QE
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQELR+KREQEVT LKK L+E
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + LE E ++L EL L
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
L+K+++S +QL D QELLQEETR KL + +++R +E E L++QL+EE A++ R
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
+ T QLS+ +++ ++ A +EA EE ++R +E E LTQ+ EK D+LE+ + RL
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
QQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + +ER+RAEAE RE+E +A
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
LSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R E +++
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE EE+RRQL +QL + E E
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQLRK+QAQMK+ RE+E+ R
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA +++E+A+E+A+ +
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q E L+ EL+ ERS + K ES
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ EEQ+EQE RE+ + K ++
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R A RR+LQR
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
Query: 1964 ELEDVTESAESMNREVTTLRNRLRRGP 1990
EL++ TES E+M REV L+++LR P
Sbjct: 1906 ELDEATESNEAMGREVNALKSKLRGPP 1932
Score = 196 bits (499), Expect = 1e-49
Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%)
Query: 1142 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1194
Q+ R+EEE+QA L + ++ LK L + + L E QE L++E +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 1195 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1247
AE+ R ++L E L + LE+ D Q R K Q++ +L++ LEEE
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962
Query: 1248 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
EAA Q+L+ A + +L +++ K R LE +S+L L+ +
Sbjct: 963 -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
+ + + + E + E++ R E++R E + ++ + + + + + +++ L
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
+L+ E +L A L +E K ++R +E + L+E L+ E AAR +A ++
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1483
+ +L + E+ + +E R + +E L + L E+T + + +++ R++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Q +++ T LEQ ++ + L+K ++ ++ A+ + + ++ E + ++ EA+
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1602
L + + AR EL + L+ E+E++ ++ GK++ + A D+
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1310
Query: 1603 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1660
+ ++L+D + E+ + +L V+ + + + ER+ LQ + + E ++ L + +
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 1661 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1713
++ D ++K + A +K+ + E+E L Q ++ K ++Q ++
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 1714 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1772
+L +++ R ++ S + +++ L AE + + A DRA +A++ ++ A
Sbjct: 1431 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1485
Query: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1825
+A L +A LE K +LE L+ E+E+ S N L R L Q+E
Sbjct: 1486 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542
Query: 1826 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1884
+ T+L E + +LE +Q L+G+ E D AR +++ L+ +L +
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 1885 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1944
E +LE E ++R L+ ++ E LK++ LQ + + ++ QL K ++K +R+L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 1945 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1990
E+A E++A +A +LQ +L + + + E L L
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1720
Query: 1991 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 2021
L+ + RLE +A EE E + G+
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 1306 bits (3379), Expect = 0.0
Identities = 735/1943 (37%), Positives = 1156/1943 (59%), Gaps = 65/1943 (3%)
Query: 56 VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113
V+VP + F A + R+ G+ AE E G+ + + DQ+ + NPPKF K EDMA L
Sbjct: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93
Query: 114 TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173
T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT +V YRGKKR E PPH
Sbjct: 94 TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153
Query: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K+ P
Sbjct: 154 IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213
Query: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 214 ------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
Query: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
LEKSR I Q K E +HIFYQ+L +L LL+ + Y F++ G ++ + E
Sbjct: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327
Query: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
T + VLGF+ EE SM ++ A++ FGN+ K ++ +QA A K L
Sbjct: 328 ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387
Query: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
+GL D + L PR+KVG +YV K Q +Q +A ALAKA YER+F W+V R+N L
Sbjct: 388 MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447
Query: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 448 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 505
Query: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 506 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSAN 562
Query: 590 FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V L +S+ +L + ++
Sbjct: 563 FQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFA 622
Query: 648 DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
+ + G+ P G G+ ++G
Sbjct: 623 N---------YAGADAPIEKGK-------------------------------GKAKKGS 642
Query: 708 -FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGI 766
F+TV L++E+L++LM L +T+P FVRCI+PN K G ++ LV+ QLRCNGVLEGI
Sbjct: 643 SFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGI 702
Query: 767 RICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSK 825
RICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++ EK++ +L++D N Y+ G +K
Sbjct: 703 RICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTK 762
Query: 826 IFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYL 885
+FF+AG+L LEE RD +++ II QA +RG LAR ++K +++ +L V+Q N A++
Sbjct: 763 VFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFM 822
Query: 886 KLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEE 945
+++W W +L+ K+KPLL+ +++ + + +E +++E ++S EL+ ++ L +
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 946 ERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKR 1005
E+ L Q++AE + A+AEE +L K +LE V E+ R+ +EEE + ++ +K++
Sbjct: 883 EKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942
Query: 1006 LQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR 1065
L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++
Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002
Query: 1066 LAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSEL 1125
+ EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1003 HQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
QE +++ + ++L +L +K+ EL A AR EDE +QL K L+E QA + E +E+L
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEET 1245
E+ER AR K EK R DL ELE + LE+ +T+ Q E+ KRE E ++++ LEE T
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1182
Query: 1246 RIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTAR 1305
HEA LR++H ++ EL EQ++ +R K EK + + E+ ++ + + + A+
Sbjct: 1183 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1242
Query: 1306 QEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLS 1365
E+ R LE Q+ E + +A + +R+ + + + Q E +S L+E E+ +L+
Sbjct: 1243 ANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT 1302
Query: 1366 KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 1425
+ + QL D + L+EE +AK AL +++ + LREQ EEE A+ R L
Sbjct: 1303 RGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLS 1362
Query: 1426 TAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1484
A +++++WR + E +A E EEA+++ A+ + + + LE+ + RLQ
Sbjct: 1363 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQ 1422
Query: 1485 QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARAL 1544
E++D +D+E+ + L+KKQR FD++LAE K + E E ++ E R
Sbjct: 1423 NEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELF 1482
Query: 1545 SLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRA 1604
L A EE E E +R+N+ L+ E+ L GK++HELE+ + E +L++
Sbjct: 1483 KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQS 1542
Query: 1605 QVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERD 1664
+ E E L E LR ++ +K + ER L +DE E+ +R + + + D
Sbjct: 1543 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLD 1602
Query: 1665 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRT 1724
E + R A+ +KK+EG+L E++ Q++ A + EA KQ++ +Q+ +K+ ++++
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR 1662
Query: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
+ +++ E+R L+AE+ L+ + ++R+R+ A+Q+ E ++ V + +
Sbjct: 1663 ANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTS 1722
Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1844
++ +K++++ L QL+ E+EE ++ +K + + EL E+ SA E
Sbjct: 1723 LINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1782
Query: 1845 RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRR 1904
++ +E+ I++L+ RL E + A K + LE+++ + E +LE E + S K +R+
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 1905 AEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1964
+E+R+KE+ Q EE+R+ +L+D ++K L+VK KRQ EEAEE+A+ + R++Q E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 1965 LEDVTESAESMNREVTTLRNRLR 1987
L++ E A+ +V LR + R
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSR 1925
Score = 226 bits (576), Expect = 2e-58
Identities = 209/959 (21%), Positives = 432/959 (45%), Gaps = 57/959 (5%)
Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS---ELQEQMVEQQQRAEELRA 1141
KL K + + E R ++ ++E +LK L+ + EL+E+MV Q +L+
Sbjct: 831 KLYFKIKPLLKSAE-REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQL 889
Query: 1142 QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1201
Q+ +++ L A R + QL+K+ + +A + E E LE E + ++R
Sbjct: 890 QVQAEQDNLADAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942
Query: 1202 LGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1258
L +E L+ +++D TL ++ + + +TE L+E + L++
Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002
Query: 1259 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQ 1318
H QAL +L + ++ K ++ LE +V +L L + R + E+ +R+LE
Sbjct: 1003 HQQALDDLQAEEDKVN----TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1058
Query: 1319 LQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDA 1378
L+ Q D E + + E+L++ EL ++ + + ++ +L K+L +A++ +
Sbjct: 1059 LKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEEL 1118
Query: 1379 QELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1438
+E L+ E A+ + + E + E+LEE A + +A+ + RR
Sbjct: 1119 EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178
Query: 1439 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDAT 1491
EE EA A R+ ++ +AE E +D L+R +++L++E LDD T
Sbjct: 1179 EEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232
Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LT 1547
++EQ + + LEK R + + E ++ EE +R+ + + A+ + L+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSVNDLTSQRAKLQTENGELS 1288
Query: 1548 RALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT 1607
R L+E++ +L R +LE L ++ K+ + L A + A + LR Q
Sbjct: 1289 RQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYE 1348
Query: 1608 ELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEER 1667
E + + + V +T++E D R E EE +++LA++L++AE +
Sbjct: 1349 EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 1668 KQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE 1727
+ + + +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 1728 EIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNL 1780
S+K + L E+ +L+ E L R + Q++ ++ +++ +
Sbjct: 1469 S-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840
+ + + ++QLE +L+ LEE +++ E + + L+ + E+ ER + K
Sbjct: 1522 TIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEK 1579
Query: 1841 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILS 1898
E Q ++ + DA R+R++ +E L + E QL R +
Sbjct: 1580 DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEA 1639
Query: 1899 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1958
K V+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R
Sbjct: 1640 QKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 1959 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
+ ++EL + +E + ++ + T+L N+ ++ + ++E ++E+A++A
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%)
Query: 918 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 974
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
Query: 975 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 1018
+EL VV + E ++ E+E E S ++Q +KK++ + +L+ +E
Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Query: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1078
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
Query: 1079 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1137
+K K K EA + ++E+ L E+K E K R+ + EL Q E ++
Sbjct: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
Query: 1138 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1197
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
Query: 1198 QRRDLG 1203
+ RD+G
Sbjct: 1923 KSRDIG 1928
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 1295 bits (3351), Expect = 0.0
Identities = 760/1955 (38%), Positives = 1133/1955 (57%), Gaps = 64/1955 (3%)
Query: 48 VEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKA 107
+ W ++ VWVP E + A ++ E + + L + ++Q MNPP+F
Sbjct: 69 IPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLL 128
Query: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
EDMA +T LNEASVLHNLR+RY +IYTYSGLFCV INPYK LP+YT ++V Y+GK+R
Sbjct: 129 EDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRR 188
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
+ PPH+YAV + AY ML++R++QS+L TGESGAGKT NTK+VIQY A VA+ G
Sbjct: 189 SDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG--- 245
Query: 228 PGVPAS-VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
PG A ++T + G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F +G +
Sbjct: 246 PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLAS 305
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSS 345
A+I++YLLEKSR I Q E S+H++YQ+L G +L+ LLL + Y F + G +
Sbjct: 306 ADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITV 365
Query: 346 PGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTA 404
+ E T ++ +LGFS +E + ++V A+L FGN+ K+++ +QA +
Sbjct: 366 DNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTES 425
Query: 405 AQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
A K L+G+ D + LL PR++VG +YV K Q+ EQ FA+ ALAKATY+RLFRWLV
Sbjct: 426 ADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLV 485
Query: 465 LRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
R+N+ LD + PRQ F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FN MFVLEQ
Sbjct: 486 SRINQTLDTKLPRQ--FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQ 543
Query: 524 EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE 583
EEY+REGI W F+DFGLDLQPCIDLIE+P G+L++L+EEC FPKA+D SF K+
Sbjct: 544 EEYKREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDN 600
Query: 584 QGGH-PKFQRPR---HLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639
G P FQ+PR + QA F V+HYAG V Y WL KN DPLN+ V + +S +
Sbjct: 601 HAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQN 660
Query: 640 RLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPP 699
RL A ++++ + GS PP S G
Sbjct: 661 RLLATLYEN---------YAGSCSTEPPKS---------------------------GVK 684
Query: 700 GGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRC 759
R + F+TV QL+KE+L++LM L T P FVRCIVPN K G ++ LVL QLRC
Sbjct: 685 EKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRC 744
Query: 760 NGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNL 818
NGVLEGIRICRQGFPNR+L+ +FRQRY IL P+AIP FMD ++A EK++ +L+LD
Sbjct: 745 NGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQ 804
Query: 819 YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQ 878
Y+ G +K+FF+AG+L LEE RD ++ ++ QA +RG L R +Q+ + AL +Q
Sbjct: 805 YQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQ 864
Query: 879 RNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQG 938
N A+ +++W W +LF K+KPLL+ + +E L A EL+ ++ + + EL+
Sbjct: 865 WNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEE 924
Query: 939 RVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQ 998
+ +E+ LA QL+AE + A+AEE L K +LE V EL R+ +EEE +
Sbjct: 925 THVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNAD 984
Query: 999 MQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1058
+ +++L+ EL+ ++ + K + EK TE K+K E++ L++ ++L+KE
Sbjct: 985 LAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1044
Query: 1059 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1118
+K L++ + EE++V +L K +L+ E + D+E L +E+K R + E+ KR+L
Sbjct: 1045 KKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKL 1104
Query: 1119 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAAL 1178
+G+ QE + + Q ++L +L +K+ EL R EDE AQ+ K ++E QA
Sbjct: 1105 EGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA 1164
Query: 1179 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238
E +E+LE+ER AR + EKQR + ELE L LE+ ++ Q+E KRE E+ L+
Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224
Query: 1239 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAEL 1298
+ LEE HEA V LR++ + EL EQ++ +R + EK + L EV +L A +
Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 1284
Query: 1299 SSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAE 1358
+L A+ E+ R E QL E + + + +R A+A+ + R Q E +S L E E
Sbjct: 1285 ETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKE 1344
Query: 1359 SKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARE 1418
+LS+ + L + + L+EE++AK AL V+A+ + LREQ EEEA A+
Sbjct: 1345 CLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQA 1404
Query: 1419 RAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLE 1477
R L A A++++WR + E +A E EEA+++ A + + + LE
Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464
Query: 1478 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1537
+ + RLQ E +D T++LE+ + L+KKQR ++ L E R EE + E E
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEER-----RRQEEEMQRELEAA 1519
Query: 1538 EREARALS-----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1592
+RE+R L L EE EA E L+R+N+ L+ E+ L GKS+ ELE+
Sbjct: 1520 QRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTK 1579
Query: 1593 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1652
+ E ++++A + E E L E LR+++ + +K + +R L +DE RR
Sbjct: 1580 KALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNH 1639
Query: 1653 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1712
+ + + D E + R A+ +KK+EG+L +L+ Q+ A + EA R MQAQ+
Sbjct: 1640 QRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQL 1699
Query: 1713 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMA 1772
KE +E + E+ Q + E+R L AE+ L+ L +R+RR A+Q+ E
Sbjct: 1700 KEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEAT 1759
Query: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELS 1832
+ + + +L +K++LE L QL E+EE ++ +K + + EL
Sbjct: 1760 ERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 1819
Query: 1833 AERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQET 1892
E+ SA E ++ LE+ ++EL+ RL E + A K + LE+K+ + E +L+ E
Sbjct: 1820 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQ 1879
Query: 1893 RERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEAS 1952
++ + K VR+ E+R+KE+ Q EE+R+ +++D ++K +VK KRQ EEAE++A+
Sbjct: 1880 KKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQAN 1939
Query: 1953 RAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
A R+ Q EL+D E A+ + LR R R
Sbjct: 1940 TNLAKYRKAQHELDDAEERADMAETQANKLRARTR 1974
Score = 249 bits (637), Expect = 1e-65
Identities = 234/935 (25%), Positives = 414/935 (44%), Gaps = 60/935 (6%)
Query: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
R EL L+ L + + EL+E V Q +L QL +++ L A R
Sbjct: 902 RAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH------ 955
Query: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221
L+KS + + + E E LE E +RR L +E L+ +++D TL
Sbjct: 956 -LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAE 1014
Query: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
+++ + + +TE L+E + L++ H QALG+L Q E+ R A
Sbjct: 1015 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL--QAEEDR--VSALT 1070
Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
K +L LE +V +L L + R + E+ +R+LE L+ Q D + + + EKL+
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401
+ +EL +S + + + ++ K++ +A+ + L+EE A+ A +RV A
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE----LEEELEAERAARARVEKQRA 1186
Query: 1402 EAAG----LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1457
EAA L E+LEE A + +A+L RR EE A EA A RR
Sbjct: 1187 EAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQA 1246
Query: 1458 EAEALTQRLAEKTETVDR----LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1513
E A L E+ +++ R LE+ + L+ E+DD ++E + ++ EK R ++
Sbjct: 1247 EGAA---ELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303
Query: 1514 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1573
L+E K V + A + + + L+R LEE++ +L R LE
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363
Query: 1574 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1633
L ++ K+ L A + + LR Q E + + + V +++
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423
Query: 1634 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1693
+E D R E EE +++LA +L++AE + + + A+ +L+ E E++ ++
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLEL-- 1481
Query: 1694 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-- 1751
E A + + + L R +EE R EE+ + +++ +GL E+ RL+
Sbjct: 1482 -----ERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536
Query: 1752 -----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEE 1806
E L R + Q++ ++ D+V+ S + + K+ LEG +++ LEE
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596
Query: 1807 QSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEED 1863
+ EL + + L +Q+E + +R + K E R+ +R ++ L+ L D
Sbjct: 1597 EGALEL--EETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL---D 1651
Query: 1864 AGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERR 1921
A RAR++ +E L E QL TR+ + R + +LKE +EE+R
Sbjct: 1652 AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQR 1711
Query: 1922 VADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTT 1981
+A +L +Q + R L +LEE + + RR ++EL + TE ++ + T
Sbjct: 1712 LAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTG 1771
Query: 1982 LRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
L N+ ++ + +EE EAEE
Sbjct: 1772 LLNQKKK----LEADLAQLSGEVEEAAQERREAEE 1802
Score = 199 bits (507), Expect = 2e-50
Identities = 241/979 (24%), Positives = 408/979 (41%), Gaps = 183/979 (18%)
Query: 897 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-----LEEERAR 949
TK K LQ Q + LQA + + + + + ++V +L+ + Q ++ ERA+
Sbjct: 1042 TKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAK 1101
Query: 950 --LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
L L+ E A+A + + +L + ++ + +S+L RV +E+ QMQ + K LQ
Sbjct: 1102 RKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1161
Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1067
+ELE LEAE AR +++ ++ ++++ E L E+ + +R+ R A
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERL---EEAGGASAGQREGCRKREA 1218
Query: 1068 EFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL-------EKLKRRLDG 1120
E E EE L++EAT+A + RK+ +G EL ++++++L+
Sbjct: 1219 ELGRLRRELEEAA-------LRHEATVAALR---RKQAEGAAELGEQVDSLQRVRQKLEK 1268
Query: 1121 ESSELQEQM------VEQQQRAEELRAQLGR-----------KEEELQAALA-------R 1156
E SEL+ ++ VE RA+ +L R K EELQ LA R
Sbjct: 1269 EKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGR 1328
Query: 1157 AEDEGGARAQLLK---------SLREAQAA--LAEAQEDLESERVARTKAEKQRRDLGEE 1205
+ E G ++LL+ S +A AA L E + LE E A++ + L +
Sbjct: 1329 LQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD 1388
Query: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
+ LR + E+ ++ Q L SK EV + + E + ++E +++ L E
Sbjct: 1389 CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQE 1448
Query: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELS------------------SLQTARQE 1307
E +E A + EK +L L+ E ++ EL +L+ R++
Sbjct: 1449 AEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ 1508
Query: 1308 GEQRRRRLELQLQEVQG------RAGDGERARAEAAEKLQRA------------------ 1343
E+ +R LE +E +G R G EA E L+R
Sbjct: 1509 EEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLS 1568
Query: 1344 ---------------------QAELENVSGALNEAESKTIRLSKELSSTEAQL------- 1375
QA LE GAL E+KT+R+ ELS +A++
Sbjct: 1569 GKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEK 1628
Query: 1376 ---------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERA 1420
Q L ETRA+ + ME + L QL A
Sbjct: 1629 DEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688
Query: 1421 GRELQTAQAQLSEWRR-RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERG 1479
+ QAQL E + R EE+ A E E+A+ R A L L E +++ ER
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQA-LERRASLLAAELEELRAALEQGERS 1747
Query: 1480 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1539
RR +QEL +AT L + L +++K + LA+ V A +ER AE + ++
Sbjct: 1748 RRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKA 1807
Query: 1540 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 1599
A + L++EQ+ LER + L ++V EL+ AEQAA
Sbjct: 1808 ITDAAMMAEELKKEQDTSAHLERMKKTLE--------------QTVRELQARLEEAEQAA 1853
Query: 1600 -NDLRAQVTELEDELTAAEDAKLR-LEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLR 1657
+ QV +LE AK+R LE + A + +H L+G R+ ++++
Sbjct: 1854 LRGGKKQVQKLE--------AKVRELEAELDAEQKKHAEALKGV--------RKHERRVK 1897
Query: 1658 DAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR 1717
+ + +E+RK KL+ +++ K Q A Q + + RK Q ++ +
Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957
Query: 1718 EVEETRTSREEIFSQNRES 1736
+ T ++ ++ R++
Sbjct: 1958 RADMAETQANKLRARTRDA 1976
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 1293 bits (3345), Expect = 0.0
Identities = 722/1944 (37%), Positives = 1151/1944 (59%), Gaps = 54/1944 (2%)
Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA
Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
+T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
Query: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 213 GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
YLLEKSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S +
Sbjct: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328
Query: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
+E T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 329 QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388
Query: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
L L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+
Sbjct: 389 YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448
Query: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 449 QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
Query: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 507 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
Query: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
FQ+P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A++
Sbjct: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
+ G E + G GG+ +
Sbjct: 624 FS------------------------------------GAQTAEGEGAGGGAKKGGKKKG 647
Query: 706 GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
F+TV L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEG
Sbjct: 648 SSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEG 707
Query: 766 IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
IRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G +
Sbjct: 708 IRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHT 767
Query: 825 KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
K+FF+AG+L LEE RD K+ +I QA RG+LAR +Q+ +++ A+ +Q N ++
Sbjct: 768 KVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSF 827
Query: 885 LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
+ ++HW W +LF K+KPLL+ ++ + +E QK+++ +S + EL+ ++ L
Sbjct: 828 MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLL 887
Query: 945 EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
+E+ L Q++AEAE A+AEE +L K +LE + E+ R +EEE + ++ +K+
Sbjct: 888 KEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 947
Query: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
+L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++
Sbjct: 948 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1007
Query: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
+ EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1008 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKL 1067
Query: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
QE +++ + ++L +L +KE E+ ++ EDE QL K ++E QA + E +E+
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
+E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
T HEA LR++H ++ EL EQ++ +R K EK + ++ E+ +L + + ++ A
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247
Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
+ E+ R LE QL E++ + + +R + + R Q E S L+E E+ +L
Sbjct: 1248 KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQL 1307
Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
S+ + Q+ + + L+EE +AK AL +++ + LREQ EEE ++ R L
Sbjct: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367
Query: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
A ++++WR + E +A E EEA+++ A+ +A + + LE+ ++RL
Sbjct: 1368 SKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Q E++D +D+E+ + L+KKQR FD++LAE K E E ++ E R
Sbjct: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
+ A EE + E L+R+N+ L+ E+ L + GK +HELE+ + EQ +L+
Sbjct: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
A + E E L E LR+++ + +K++ +R + +DE ++ +R + + +
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTL 1607
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
D E + R A+ +KK+EG+L E++ Q+ A + EA++ R Q +K+ +++
Sbjct: 1608 DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDAL 1667
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
S+E++ Q E+R L+AE+ L+ L ++R+R+ A+Q+ + ++ V +
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
+++ K++LE + Q++ E+E+ + ++ +K + + EL E+ SA E
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
++ +E+ +++L+ RL E + A K I LE+++ + E ++E E + + K +R
Sbjct: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ A R+LQ
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
ELE+ E A+ +V LR + R
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSR 1931
Score = 224 bits (572), Expect = 5e-58
Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)
Query: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R +
Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
Query: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221
QL+K+ + +A + E E E E + ++R L +E L+ +++D TL
Sbjct: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
++ + + +TE L+E + L++ H Q L +L + ++
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401
+ + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + +
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
Query: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461
E + E+LEE A + +A+ + RR EE EA R+ ++
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
Query: 1462 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1519
+AE E +D L+R +++L++E + M+++ V T+ K + +++ E++
Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 1520 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
+ L++ EE ++ A+ + + +R L+E++ +L R +A ++E L
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Query: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634
++ K+ + L A + + + LR Q E ++ + A + V +T++
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
Query: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694
E D R E EE +++LA++L+ AE + + +++L+ E+E+L +
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
Query: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1751
K+ R + E ++ EET E S+K + L E+ +++
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
Query: 1752 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE +
Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
Query: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
++ E + ++ L++ + +E+ +R + K E Q I+ + DA R
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
Query: 1868 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1925
+R+ +E L + E QL R + + R + LK+ + +++ R +
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
Query: 1926 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1985
L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
Query: 1986 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
++ + L+E ++E+A++A
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
Score = 191 bits (486), Expect = 5e-48
Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%)
Query: 897 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058
Query: 948 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
+L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178
Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
K R+ LE+ + + AA E E++ +L +++ K E I D+
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
+ K + LEK+ R L+ + SEL+ + EQQ+ +L AQ GR + E + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
++ +QL + + + E + LE E A+ + + + LR + E+ +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358
Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
S Q SK EV + + E + ++E +++ Q L E +E
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418
Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
+ EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477
Query: 1339 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
K R+ EL + A E+ + L +E + + ++ D E + E + L +
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537
Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
+E E L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
R E++ L + + + R +++++ +L++ + L ++ + + R +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657
Query: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1571
+ + + A+ +E + + E RA L +EE + E+ ER + EL
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717
Query: 1572 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1615
+L+++K D+ + E+E + A A + +T+ + +EL
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 1616 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1667
+D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + E+
Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Query: 1668 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1706
K+ AV +K E ++EL +A++ S + EEA +Q
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Query: 1707 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
A+ ++L E+EE + ++++ ++ R+K E + EE
Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 1293 bits (3345), Expect = 0.0
Identities = 722/1944 (37%), Positives = 1151/1944 (59%), Gaps = 54/1944 (2%)
Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA
Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
+T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
Query: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 213 GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
YLLEKSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S +
Sbjct: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328
Query: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
+E T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 329 QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388
Query: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
L L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+
Sbjct: 389 YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448
Query: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 449 QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
Query: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 507 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
Query: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
FQ+P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A++
Sbjct: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
+ G E + G GG+ +
Sbjct: 624 FS------------------------------------GAQTAEGEGAGGGAKKGGKKKG 647
Query: 706 GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
F+TV L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEG
Sbjct: 648 SSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEG 707
Query: 766 IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
IRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G +
Sbjct: 708 IRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHT 767
Query: 825 KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
K+FF+AG+L LEE RD K+ +I QA RG+LAR +Q+ +++ A+ +Q N ++
Sbjct: 768 KVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSF 827
Query: 885 LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
+ ++HW W +LF K+KPLL+ ++ + +E QK+++ +S + EL+ ++ L
Sbjct: 828 MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLL 887
Query: 945 EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
+E+ L Q++AEAE A+AEE +L K +LE + E+ R +EEE + ++ +K+
Sbjct: 888 KEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 947
Query: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
+L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++
Sbjct: 948 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1007
Query: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
+ EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1008 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKL 1067
Query: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
QE +++ + ++L +L +KE E+ ++ EDE QL K ++E QA + E +E+
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
+E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
T HEA LR++H ++ EL EQ++ +R K EK + ++ E+ +L + + ++ A
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247
Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
+ E+ R LE QL E++ + + +R + + R Q E S L+E E+ +L
Sbjct: 1248 KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQL 1307
Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
S+ + Q+ + + L+EE +AK AL +++ + LREQ EEE ++ R L
Sbjct: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367
Query: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
A ++++WR + E +A E EEA+++ A+ +A + + LE+ ++RL
Sbjct: 1368 SKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Q E++D +D+E+ + L+KKQR FD++LAE K E E ++ E R
Sbjct: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
+ A EE + E L+R+N+ L+ E+ L + GK +HELE+ + EQ +L+
Sbjct: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
A + E E L E LR+++ + +K++ +R + +DE ++ +R + + +
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTL 1607
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
D E + R A+ +KK+EG+L E++ Q+ A + EA++ R Q +K+ +++
Sbjct: 1608 DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDAL 1667
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
S+E++ Q E+R L+AE+ L+ L ++R+R+ A+Q+ + ++ V +
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
+++ K++LE + Q++ E+E+ + ++ +K + + EL E+ SA E
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
++ +E+ +++L+ RL E + A K I LE+++ + E ++E E + + K +R
Sbjct: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ A R+LQ
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
ELE+ E A+ +V LR + R
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSR 1931
Score = 224 bits (572), Expect = 5e-58
Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)
Query: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R +
Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
Query: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221
QL+K+ + +A + E E E E + ++R L +E L+ +++D TL
Sbjct: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
++ + + +TE L+E + L++ H Q L +L + ++
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401
+ + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + +
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
Query: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461
E + E+LEE A + +A+ + RR EE EA R+ ++
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
Query: 1462 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1519
+AE E +D L+R +++L++E + M+++ V T+ K + +++ E++
Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 1520 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
+ L++ EE ++ A+ + + +R L+E++ +L R +A ++E L
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Query: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634
++ K+ + L A + + + LR Q E ++ + A + V +T++
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
Query: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694
E D R E EE +++LA++L+ AE + + +++L+ E+E+L +
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
Query: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1751
K+ R + E ++ EET E S+K + L E+ +++
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
Query: 1752 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE +
Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
Query: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
++ E + ++ L++ + +E+ +R + K E Q I+ + DA R
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
Query: 1868 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1925
+R+ +E L + E QL R + + R + LK+ + +++ R +
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
Query: 1926 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1985
L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
Query: 1986 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
++ + L+E ++E+A++A
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
Score = 191 bits (486), Expect = 5e-48
Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%)
Query: 897 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058
Query: 948 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
+L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178
Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
K R+ LE+ + + AA E E++ +L +++ K E I D+
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
+ K + LEK+ R L+ + SEL+ + EQQ+ +L AQ GR + E + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
++ +QL + + + E + LE E A+ + + + LR + E+ +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358
Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
S Q SK EV + + E + ++E +++ Q L E +E
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418
Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
+ EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477
Query: 1339 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
K R+ EL + A E+ + L +E + + ++ D E + E + L +
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537
Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
+E E L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
R E++ L + + + R +++++ +L++ + L ++ + + R +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657
Query: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1571
+ + + A+ +E + + E RA L +EE + E+ ER + EL
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717
Query: 1572 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1615
+L+++K D+ + E+E + A A + +T+ + +EL
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 1616 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1667
+D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + E+
Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Query: 1668 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1706
K+ AV +K E ++EL +A++ S + EEA +Q
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Query: 1707 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
A+ ++L E+EE + ++++ ++ R+K E + EE
Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 1291 bits (3340), Expect = 0.0
Identities = 726/1912 (37%), Positives = 1129/1912 (59%), Gaps = 58/1912 (3%)
Query: 84 ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143
E G L + DQ+ MNPPK+ K EDMA +T L+E VL+NL+ERY + +IYTYSGLFCV
Sbjct: 67 EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126
Query: 144 VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203
+NPYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG
Sbjct: 127 TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186
Query: 204 KTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVK 263
KT NTK+VIQY A +A + + +K+ S G LE Q++ ANP+LEAFGNAKTV+
Sbjct: 187 KTVNTKRVIQYFATIAVTGEKKKDE------SGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 264 NDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQL 323
NDNSSRFGKFIRI+F G + A+IETYLLEKSR Q K E S+HIFYQ+ L
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300
Query: 324 KADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVL 381
LL+ + Y F++ G + P ++E T ++ +LGF+ EE +S+ ++ AV+
Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360
Query: 382 QFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTK 441
+GN+ K+++ +QA A K L L D +AL PR+KVG +YV K QT
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 442 EQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQ 500
+Q A+ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS EQ
Sbjct: 421 QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQ 478
Query: 501 LCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLA 560
LCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL CI+LIE+P G+ +
Sbjct: 479 LCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFS 535
Query: 561 LLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANE 617
+L+EEC FPKATD SF K+ Q G FQ+P+ ++ +A+ FS++HYAG VDY
Sbjct: 536 ILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITG 595
Query: 618 WLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAI 677
WL KN DPLND V L +S + A ++ S SAE SSA
Sbjct: 596 WLDKNKDPLNDTVVGLYQKSAMKTLASLF------------------STYASAEADSSA- 636
Query: 678 SPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 737
G + + F+TV L++E+L++LM L +T+P FVRCI
Sbjct: 637 --------------------KKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCI 676
Query: 738 VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 797
+PN K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G
Sbjct: 677 IPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEG 736
Query: 798 -FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 856
F+D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ II QA R
Sbjct: 737 QFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCR 796
Query: 857 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 916
G+L R +QK Q++ AL +Q N A++ ++HW W +LF K+KPLL+ ++ +
Sbjct: 797 GFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMK 856
Query: 917 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 976
+E QK ++ +S + EL+ ++ L +E+ L Q+++EA+ A+AEE +L K
Sbjct: 857 EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKI 916
Query: 977 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1036
+LE + E+ R EEEE + ++ +K++L+ EL+ ++ E K++ EK TE
Sbjct: 917 QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
Query: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096
K+K E++ L++ +KLSKE+K L++ + EE+KV L K + K E + D
Sbjct: 977 KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036
Query: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156
+E L +E+K R +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ +++
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096
Query: 1157 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1216
EDE QL K ++E QA + E E++E+ER +R KAEKQR DL ELE + LE+
Sbjct: 1097 IEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Query: 1217 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1276
+T+AQ EL KRE E +L++ LEE T HEA V LR++H ++ EL EQ++ +R
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRV 1216
Query: 1277 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1336
K EK + L+ E +L + ++ A+ E+ R LE Q+ E++ + + +R +
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDL 1276
Query: 1337 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1396
+ R Q E S L+E ++ +LS+ ++ Q+ + + L+EET+AK AL +
Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336
Query: 1397 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRA 1455
++ + LREQ EEE + R L A +++++WR + E +A E EEA+++
Sbjct: 1337 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
Query: 1456 AREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1515
A+ + + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++L
Sbjct: 1397 AQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL 1456
Query: 1516 AEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1575
+E K E E ++ E R + EE + E L R+N+ L+ E+ L
Sbjct: 1457 SEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516
Query: 1576 SSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHE 1635
+ GK +HELE+ + EQ +++A + E E L E LR+++ + +K++ +
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576
Query: 1636 RDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAG 1695
R + +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A
Sbjct: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636
Query: 1696 QGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELA 1755
+ E+++ R Q +KE +++ +E++ Q E+R L+AE+ L L
Sbjct: 1637 RLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLE 1696
Query: 1756 ASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLND 1815
++R+R+ A+Q+ + ++ V + +++ K++LE + QL+ E+EE S +
Sbjct: 1697 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE 1756
Query: 1816 RYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIA 1875
+ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A K I
Sbjct: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1816
Query: 1876 ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNL 1935
LE+++ + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K
Sbjct: 1817 KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQA 1876
Query: 1936 RVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
+VK KRQ EEAEE+++ + R+LQ ELE+ E A+ +V LR + R
Sbjct: 1877 KVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
Score = 227 bits (579), Expect = 8e-59
Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%)
Query: 897 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
+K K LQ T Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
Query: 948 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
+L L+ E + E + +L + ++ E +S L +++ +E+ Q+Q + K LQ
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1067
I+EL +EAE +R K + ++ ++++ E L E+ S + +L + R A
Sbjct: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172
Query: 1068 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1105
EF + EE + LR K+ ++A++ + +L KE+
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Query: 1106 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1155
K + LEK+ R L+ + SEL+ + EQQ+ +L AQ R + E
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
Query: 1156 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1215
+ +++ +QL +S + + + E + LE E A+ + + + LR + E+
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 1216 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1275
+ Q SK EV + + E + ++E +++ Q L E E +E
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
Query: 1276 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1335
+ EKT+ L+ EV +L ++ A ++++R + L E + + + + A E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471
Query: 1336 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1394
A++K R+ EL V E+ + L +E + + ++ D E + E + L
Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
Query: 1395 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1454
+ +E E ++ LEE A+ E ++ Q +L++ + +
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576
Query: 1455 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1514
+++AEK E +D+L+R R+ + + +T+D E + + + KK+ + D
Sbjct: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626
Query: 1515 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1568
E A L A R +G +E + L L AL +++ +E+L ER+ L+
Sbjct: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685
Query: 1569 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1628
AE+E L ++ + + ER+ ++AEQ D +V L + T+ + K +LE V
Sbjct: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
Query: 1629 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1685
L+++ E +Q A E+ + K + DA + +E +K++ + +K LE ++
Sbjct: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794
Query: 1686 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1744
+L+ ++ A Q + KQ++K++A+++EL EVE + E R+ E+R+K L
Sbjct: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854
Query: 1745 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1797
+ VLRLQ+ L +A+ ++ + + E A+E +N NLSK
Sbjct: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900
Query: 1798 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1834
+L+ ELEE + +++ + KL ++ + T++SAE
Sbjct: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 219 bits (557), Expect = 3e-56
Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%)
Query: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
K+K L LK T +M + +K + EL K + + EL+E+MV + +
Sbjct: 838 KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889
Query: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
L+ Q+ + + L A R E QL+K+ + +A + E E E E + +
Sbjct: 890 LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942
Query: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 943 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
Query: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
++ H Q L +L + ++ K + LE +V +L L + R + E+ +R+L
Sbjct: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058
Query: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
E L+ Q D E + + EKL++ + E+ N+ + + ++ I+L K++ +A++
Sbjct: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118
Query: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
+ E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178
Query: 1436 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1492
R EE EA A R+ ++ +AE E +D L+R +++L++E + M
Sbjct: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Query: 1493 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1548
DL + +S + K + L ++ + + EE++R A+ + A +R
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
Query: 1549 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
L+E+ +L R +A ++E L ++ K+ + L A + + + LR Q E
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 1609 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1668
++ + A + V +T++E D R E EE +++LA++L++AE +
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
Query: 1669 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1728
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
Query: 1729 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1788
++R L ++ ++L R + QQ+ ++ +++A G + +
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
Query: 1789 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1848
K+Q+E +++ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590
Query: 1849 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1906
+ + DA R+R+ +E L + E QL R S + R +
Sbjct: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
Query: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1966
LKE L +++ R + L++QL R L+ ++EE + + R+ ++EL
Sbjct: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710
Query: 1967 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
D +E + ++ + T+L N ++ ++ V +V ++E ++E+A++A
Sbjct: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 1288 bits (3333), Expect = 0.0
Identities = 730/1944 (37%), Positives = 1148/1944 (59%), Gaps = 59/1944 (3%)
Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
A+ +V + ++ + + VE E R L + + + MNPPKF + EDMA
Sbjct: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y +VE YRGKKR E P
Sbjct: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ K+
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK--- 209
Query: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 210 ---DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266
Query: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
YLLEKSR Q K E S+HIFYQ+L +L LL+ + Y F++ G +
Sbjct: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDD 326
Query: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
E T ++ +LGF+ EE + ++ AV+ +GN+ K+++ +QA A K
Sbjct: 327 AEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTA 386
Query: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
L+GL +D +AL PR+KVG +YV K QT +Q A+ AL+K+ YE+LF W+V R+N+
Sbjct: 387 YLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQ 446
Query: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
LD + PRQ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 447 QLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 504
Query: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 505 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 561
Query: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
FQ+P+ ++ +A+ FS++HYAG VDY + WL KN DPLN+ V L +S++RL A +
Sbjct: 562 NNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL 621
Query: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
+ +F + S G ++V+ + +
Sbjct: 622 Y-------------ATFATADADS-----------------GKKKVA---------KKKG 642
Query: 706 GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
F+TV L++E+L++LM+ L T+P FVRCI+PN K G +E LVL QLRCNGVLEG
Sbjct: 643 SSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEG 702
Query: 766 IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
IRICR+GFPNRIL+ +F+QRY +L +AIP+G F+D K+ACEK++ ++++D Y+ G +
Sbjct: 703 IRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHT 762
Query: 825 KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
K+FF+AG+L LEE RD ++ +I QA RG+L R FQK Q++ ++ +Q N ++
Sbjct: 763 KVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSF 822
Query: 885 LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
+ ++HW W +LF K+KPLL+ ++ + +E QK ++ +S + EL+ ++ L
Sbjct: 823 MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLV 882
Query: 945 EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
+E+ L Q++AE+E +AEE +L K +LE + E+ R +EEE + ++ +K+
Sbjct: 883 QEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKR 942
Query: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
+L+ EL+ ++ E K++ EK TE K+K E+L L++ +KL++E+K L++
Sbjct: 943 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 1002
Query: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
+ EE+KV SLNK + K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1003 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 1062
Query: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
QE +++ + ++L +L +K+ E ++ EDE Q K ++E QA + E +E+
Sbjct: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 1122
Query: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
+E+ER R K EKQR D ELE L LE+ T+ Q EL KRE E +L++ LEE
Sbjct: 1123 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEA 1182
Query: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
T HEA V LR++H ++ EL EQ++ +R K EK + + E+ +L + + S+ +
Sbjct: 1183 TLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKS 1242
Query: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
+ E+ R LE QL E +G+ + +R+ +E + R Q E +S L E ES +L
Sbjct: 1243 KANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQL 1302
Query: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
S+ + Q + + L+EE +AK AL +++ + LREQ EEE + R L
Sbjct: 1303 SRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1362
Query: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
A +++++WR + E +A E EEA+++ A+ + +++ LE+ ++RL
Sbjct: 1363 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL 1422
Query: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Q E++D +D+E+ L + L+KKQR FD++LAE K + E E + E R
Sbjct: 1423 QGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 1482
Query: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
L A EE + E ++R+N+ L E+ L + GK++HELE++ + E D++
Sbjct: 1483 FKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQ 1542
Query: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
+ E E L E LR+++ + +K++ +R + +DE E+ +R + + +
Sbjct: 1543 LALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602
Query: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
D E + R A+ +KK+EG+L E++ Q++ A + E +K LR +Q Q+K+ +++
Sbjct: 1603 DAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDAL 1662
Query: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
+E++ Q E+R L+AEV L+ L ++RAR+ A+Q+ + + V +
Sbjct: 1663 RGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 1722
Query: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
+++ K++LE L QL+ E+E+ ++ ++ +K + + EL E+ SA E
Sbjct: 1723 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1782
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
++ LE+ +++L+ RL E + A K I LE+++ + E +LE E ++ S K +R
Sbjct: 1783 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842
Query: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
+ E+R+KE+ Q EE+R+ +L+D ++K ++VK KRQ EEA+E+A+ R+ Q
Sbjct: 1843 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1902
Query: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
ELE+ E A+ +V LR + R
Sbjct: 1903 ELEEAEERADIAESQVNKLRAKTR 1926
Score = 145 bits (365), Expect = 5e-34
Identities = 188/868 (21%), Positives = 357/868 (41%), Gaps = 172/868 (19%)
Query: 885 LKLRHWQWWRLFTKVKPL----LQVTRQDEVLQARAQELQ-----------KVQELQQQS 929
LK + +++ +L +KV+ LQ ++ + LQAR +EL+ K ++ +
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
Query: 930 AREVGELQGRV--------AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 981
ARE+ EL R+ Q+E + R AE L+ +L + +AA +++
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200
Query: 982 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEA 1036
V+EL ++ + ++++ EK + I +L + +E+ ++ L+ LE +EA
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096
+ K E ++ S+L+ ++ L+ E S Q E+E V L++ + + +
Sbjct: 1261 RGKNEE-----IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315
Query: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156
++ +L +E K + L + + L+EQ E+Q+ EL+ L + E+ +
Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375
Query: 1157 AEDEGGARAQLLKSLREAQAA-LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1215
E + R + L+ ++ A L +++E +E+ EK ++ L E+E L ++E
Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
Query: 1216 T------LDSTNAQ-----QELRSKREQEVTELKKTLEEETRI----------HEAAVQE 1254
LD E ++K E+ EL+ +L+E + +E A+ +
Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
Query: 1255 LR------QRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1308
L + Q + +L EQ+ + + EK+R +E E ++++ L + A +
Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
Query: 1309 EQRRRRLELQLQEVQGR----------------------------AGDGE-RARAEAAEK 1339
E + R++L+L +V+ A D E R+R EA
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
Query: 1340 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL------QEETRAKLALG 1393
++ + +L + L+ A + K L S + QL D Q L QE+ + +LA+
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675
Query: 1394 SR-VRAMEAEAAGLREQLEEEAAARERAGREL----------QTAQAQLSEWRRRQEEEA 1442
R ++AE LR LE+ AR+ A +EL T L +++ E +
Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735
Query: 1443 GALEA-----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
L++ EE ++A +A + + L ++ +T LER ++ L+Q + D
Sbjct: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795
Query: 1492 MDLEQQRQLVSTLEKKQ-----------------------------RKFDQLLAE----- 1517
L++ QL KKQ RK+++ + E
Sbjct: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855
Query: 1518 --EKAAVLRAVE--------------ERERAEAEGREREARALSLTRALEEEQEAREELE 1561
++ VLR + + E A+ + + LEE +E + E
Sbjct: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915
Query: 1562 RQNRALRAELEALLSSKDDVGKSVHELE 1589
Q LRA+ SS+ VHE E
Sbjct: 1916 SQVNKLRAKTRDFTSSR----MVVHESE 1939
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 1288 bits (3333), Expect = 0.0
Identities = 719/1946 (36%), Positives = 1155/1946 (59%), Gaps = 60/1946 (3%)
Query: 52 ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
A+ V+V F A + R+ G+ A+ E +G + + DQ+ MNPPK+ K ED
Sbjct: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90
Query: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E
Sbjct: 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150
Query: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229
PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210
Query: 230 VPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 289
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+I
Sbjct: 211 TSGKMQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
Query: 290 ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG- 347
ETYLLEKSR Q K E S+HIFYQ++ L LL+ + Y F++ G + P
Sbjct: 267 ETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 348 QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQK 407
++E T ++ +LGF+ +E +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 408 LCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRL 467
L L D +AL PR+KVG +YV K QT +Q A+ ALAKA Y+++F W+V R+
Sbjct: 387 AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446
Query: 468 NRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 526
N+ LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY
Sbjct: 447 NQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
Query: 527 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-G 585
++EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G
Sbjct: 505 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561
Query: 586 GHPKFQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
FQ+P+ + +A FS++HYAG VDY WL KN DPLN+ V L +S + A
Sbjct: 562 KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621
Query: 644 EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
++ G G E + G G GG+
Sbjct: 622 LLFV------------------------------------GATGAE--AEAGGGKKGGKK 643
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
+ F+TV L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVL
Sbjct: 644 KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVL 703
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVG 822
EGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G
Sbjct: 704 EGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFG 763
Query: 823 QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
+K+FF+AG+L LEE RD K+ +I QA RG+LAR +QK +++ ++ +Q N
Sbjct: 764 HTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVR 823
Query: 883 AYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQ 942
A++ ++HW W +L+ K+KPLL+ ++ + +E +K +E ++ + EL+ ++
Sbjct: 824 AFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVT 883
Query: 943 LEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTE 1002
L +E+ L Q++AEA+ A+AEE +L K +LE + E+ R +EEE + ++ +
Sbjct: 884 LMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
Query: 1003 KKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1062
K++L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 1063 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1122
++ + EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1004 QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1063
Query: 1123 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1182
QE ++ + ++L +L +KE E+ ++ EDE QL K ++E QA + E +
Sbjct: 1064 KLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 1123
Query: 1183 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1242
E++E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LE
Sbjct: 1124 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 1243 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQ 1302
E T HEA LR++H ++ EL EQ++ +R K EK + ++ E+ +L + + ++
Sbjct: 1184 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 1243
Query: 1303 TARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTI 1362
A+ E+ R LE QL E++ + + +R + + R Q E S L+E ++
Sbjct: 1244 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVS 1303
Query: 1363 RLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGR 1422
+LS+ + Q+ + + L+EE +AK AL +++ + LREQ EEE A+ R
Sbjct: 1304 QLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363
Query: 1423 ELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR 1481
+ A +++++WR + E +A E EEA+++ A+ + + + LE+ ++
Sbjct: 1364 AMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQ 1423
Query: 1482 RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA 1541
RLQ E++D +D+E+ + L+KKQR FD++LAE K E E ++ E R
Sbjct: 1424 RLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLST 1483
Query: 1542 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1601
+ A EE + E L+R+N+ L+ E+ L + GK +HELE+ + EQ ++
Sbjct: 1484 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSE 1543
Query: 1602 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 1661
L+A + E E L E LR+++ + +K++ +R + +DE ++ +R + + +
Sbjct: 1544 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQS 1603
Query: 1662 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE 1721
D E + R A+ +KK+EG+L E++ Q+ A + EA++ R QA +K+ +++
Sbjct: 1604 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDD 1663
Query: 1722 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1781
S+E++ Q E+R L+AE+ L+ L ++R+R+ A+Q+ + ++ V +
Sbjct: 1664 ALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1723
Query: 1782 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA 1841
+++ K++LE + Q++ E+E+ + ++ +K + + EL E+ SA
Sbjct: 1724 NTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1783
Query: 1842 ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
E ++ LE+ +++L+ RL E + A K I LE+++ + E ++E E + + + K
Sbjct: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843
Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
+R+ E+++KE+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ + RR+
Sbjct: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903
Query: 1962 QRELEDVTESAESMNREVTTLRNRLR 1987
Q ELE+ E A+ +V LR + R
Sbjct: 1904 QHELEEAEERADIAESQVNKLRVKSR 1929
Score = 227 bits (579), Expect = 8e-59
Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%)
Query: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
Query: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 891 LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
Query: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
++ H Q L +L + ++ K ++ LE +V +L L + R + E+ +R+L
Sbjct: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
Query: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
E L+ Q D E + + EKL++ + E+ + + + ++ ++L K++ +A++
Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 1436 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1494
R EE EA R++ A L +++ +LE+ + ++ E+DD ++
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
Query: 1495 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1550
E + LEK R + L+E K EE++R + + AR + +R L
Sbjct: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295
Query: 1551 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1610
+E+ +L R +A ++E L ++ K+ L A + + + LR Q E +
Sbjct: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355
Query: 1611 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1670
+ + A + V +T++E D R E EE +++LA++L+DAE + +
Sbjct: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415
Query: 1671 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
+++L+ E+E+L + K+ R + E ++ EET E
Sbjct: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475
Query: 1731 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1790
++R L ++ ++L R + QQ+ ++ +++A G + + K+
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
Query: 1791 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850
Q+E +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593
Query: 1851 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1908
I+ + DA R+R+ +E L + E QL R + + R +
Sbjct: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653
Query: 1909 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1968
LK+ L +++ R + L++QL R L+ ++EE + + R+ ++EL D
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713
Query: 1969 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
+E + ++ + T+L N ++ + ++E ++E+A++A
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762
Score = 189 bits (480), Expect = 2e-47
Identities = 199/947 (21%), Positives = 418/947 (44%), Gaps = 94/947 (9%)
Query: 897 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 997 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056
Query: 948 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
+L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116
Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176
Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
K R+ LE+ + + AA E E++ +L +++ K E I D+
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236
Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
+ K + LEK+ R L+ + SE++ + EQQ+ +L AQ R + E + +
Sbjct: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296
Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
++ +QL + + + E + LE E A++ + + + LR + E+ +
Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356
Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
+ Q SK EV + + E + ++E +++ Q L + E +E
Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCA 1416
Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
+ EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1475
Query: 1339 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
K R+ EL + A E+ + L +E + + ++ D E + E + L +
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
+E E + L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHI 1595
Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
R E++ L + + + R +++++ +L++ + L ++ + + R +L
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILK 1655
Query: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1571
+ + + A+ +E + + E RA L +EE + E+ ER + EL
Sbjct: 1656 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1715
Query: 1572 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1615
+L+++K D+ + E+E + A A + +T+ + +EL
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775
Query: 1616 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1667
+D LE + L+ Q +DLQ R DEA G+++ ++L ++R+ E E + E+
Sbjct: 1776 EQDTSAHLERMKKNLE-QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834
Query: 1668 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1706
K+ AV +K E +++EL +A++ S + EEA +Q
Sbjct: 1835 KRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894
Query: 1707 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
++ + + E+EE + ++++ ++ R+K E + EE
Sbjct: 1895 VNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 1285 bits (3324), Expect = 0.0
Identities = 726/1942 (37%), Positives = 1150/1942 (59%), Gaps = 63/1942 (3%)
Query: 57 WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
+VP + F A + R+ G+ AE E +G+ + + DQ+ + NPPKF K EDMA LT
Sbjct: 38 FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94
Query: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174
L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+
Sbjct: 95 FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154
Query: 175 YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVPAS 233
+++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+K+
Sbjct: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDN----- 209
Query: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
+ + G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 210 -ANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
Query: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
LEKSR I Q K E ++HIFYQ+L +L LL+ + Y F++ G S + E
Sbjct: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSE 328
Query: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
T + VLGF+ EE + ++ A++ +GN+ K+++ +QA A K L
Sbjct: 329 ELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYL 388
Query: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
+GL D + L PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V R+N L
Sbjct: 389 MGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATL 448
Query: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 449 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 506
Query: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 507 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNN 563
Query: 590 FQRPRHLR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V AL +S+ +L A ++
Sbjct: 564 FQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFS 623
Query: 648 DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
S+ + G + + GG+ +
Sbjct: 624 -------------SYATADTGDSGKSK-------------------------GGKKKGSS 645
Query: 708 FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 767
F+TV L++E+L++LM L T+P FVRCI+PN K G ++ LV+ QLRCNGVLEGIR
Sbjct: 646 FQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIR 705
Query: 768 ICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKI 826
ICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++ EK++ +L++D N Y+ G +K+
Sbjct: 706 ICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKV 765
Query: 827 FFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLK 886
FF+AG+L LEE RD +++ II QA ARG L R F+K +++ AL V+Q N A++
Sbjct: 766 FFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG 825
Query: 887 LRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEE 946
+++W W +L+ K+KPLL+ ++ + +E +++E ++S EL+ ++ L +E
Sbjct: 826 VKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE 885
Query: 947 RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006
+ L Q++AE + +AEE +L K +LE V E+ R+ +EEE + ++ +K++L
Sbjct: 886 KNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKL 945
Query: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066
+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++
Sbjct: 946 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1005
Query: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQ 1126
+ EE+KV SL+K ++K E + D+E L +E+K R +LE+ KR+L+G+ Q
Sbjct: 1006 QQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1065
Query: 1127 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1186
E +++ + +L +L +KE ++ ++ EDE QL K L+E QA + E +E+LE
Sbjct: 1066 ESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE 1125
Query: 1187 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETR 1246
+ER AR K EK R DL ELE + LE+ +T+ Q E+ KRE E ++++ LEE T
Sbjct: 1126 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
Query: 1247 IHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQ 1306
HEA LR++H ++ EL EQ++ +R K EK + + E+ ++ + + + A+
Sbjct: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245
Query: 1307 EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366
E+ R LE Q E + + + +R+ + + + Q E ++ L E E+ +L++
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305
Query: 1367 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQT 1426
S Q+ D + L+EE +AK AL +++ + LREQ EEE A+ R L
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365
Query: 1427 AQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1485
A +++++WR + E +A E EEA+++ A+ + + + LE+ + RLQ
Sbjct: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 1486 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545
E++D +D+E+ + L+KKQR FD++LAE K + E E ++ E R
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485
Query: 1546 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1605
L A EE E E +R+N+ L+ E+ L + GK+VHELE+ + E +L++
Sbjct: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
Query: 1606 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE 1665
+ E E L E LR ++ +K + ER L +DE E+ +R + + + D
Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
Query: 1666 ERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
E + R + +KK+EG+L E++ Q++ A + EA KQ++ +Q+ +K+ ++++ +
Sbjct: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
Query: 1726 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1785
+++ E+R L+AE+ L+ + ++R+R+ A+Q+ E ++ V + ++
Sbjct: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725
Query: 1786 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1845
+ +K+++E L QL+ E+EE ++ +K + + EL E+ SA E +
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1785
Query: 1846 QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1905
+ +E+ I++L+ RL E + A K + LE+++ + E +LE E + S K +R++
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKS 1845
Query: 1906 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1965
E+R+KE+ Q EE+++ +L+D ++K L+VK KRQ EEAEE+A+ + R++Q EL
Sbjct: 1846 ERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1905
Query: 1966 EDVTESAESMNREVTTLRNRLR 1987
++ E A+ +V LR + R
Sbjct: 1906 DEAEERADIAESQVNKLRAKSR 1927
Score = 236 bits (601), Expect = 2e-61
Identities = 213/954 (22%), Positives = 431/954 (45%), Gaps = 57/954 (5%)
Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1144
K++ ++ + E KEE GR +++ + + EL+E+MV Q +L+ Q+
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR--IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQ 894
Query: 1145 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1204
+++ L A R + QL+K+ + +A + E E LE E + ++R L +
Sbjct: 895 AEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED 947
Query: 1205 ELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1261
E L+ +++D TL ++ + + +TE L+E + L++ H Q
Sbjct: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 1262 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1321
AL +L Q+E+ + + K+++ LE +V +L L + R + E+ +R+LE L+
Sbjct: 1008 ALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
Query: 1322 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1381
Q D E + + EKL++ + ++ + + + + ++L K+L +A++ + +E
Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEE 1123
Query: 1382 LQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE 1441
L+ E A+ + + E + E+LEE A + +A+ + RR EE
Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183
Query: 1442 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATMDL 1494
EA A R+ ++ +AE E +D L+R +++L++E LDD T ++
Sbjct: 1184 TLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Query: 1495 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQ 1554
EQ + + LEK R + E + + A + + + L R LEE++
Sbjct: 1238 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1297
Query: 1555 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1614
+L R + ++E L ++ GK+ + L A + A + LR Q E +
Sbjct: 1298 ALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKA 1357
Query: 1615 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1674
+ + V +T++E D R E EE +++LA++L+DAE + + +
Sbjct: 1358 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLE 1417
Query: 1675 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1734
+ +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1418 KTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES------ 1471
Query: 1735 ESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1787
S+K + L E+ +L+ E L R + Q++ ++ +++ G + + +
Sbjct: 1472 -SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 1788 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AESG 1844
++QLE +L+ LEE +++ E + + L+ + E+ ER + K E
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEMEQA 1588
Query: 1845 RQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLV 1902
++ +R + L+ L DA R+R+++ +E L + E QL R + K V
Sbjct: 1589 KRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645
Query: 1903 RRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQ 1962
+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R+ +
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Query: 1963 RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
+EL + +E + ++ + T+L N+ ++ T + +EE V AEE
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755
Score = 71.2 bits (173), Expect = 9e-12
Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%)
Query: 918 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 974
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
Query: 975 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 1018
+EL VV + E ++ E+E E S ++Q +KK+++ + +L++ +E
Sbjct: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746
Query: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1078
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804
Query: 1079 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1137
+K K K EA + ++E L E+K E K R+ + EL Q E ++
Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864
Query: 1138 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1197
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924
Query: 1198 QRRDLG 1203
+ RD+G
Sbjct: 1925 KSRDIG 1930
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 1276 bits (3301), Expect = 0.0
Identities = 713/1937 (36%), Positives = 1143/1937 (59%), Gaps = 58/1937 (2%)
Query: 59 PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118
P E + R+ G+ A+ E +G + + DQ+ MNPPK+ K EDMA +T L+E
Sbjct: 43 PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99
Query: 119 ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178
+VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+++++
Sbjct: 100 PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159
Query: 179 EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVS 238
+ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE PAS
Sbjct: 160 DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEE--PASGKM-- 215
Query: 239 YGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSR 298
G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 216 QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 275
Query: 299 AIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQET 356
Q K E S+HIFYQ+L +L LL+ + + F++ G + P ++E T
Sbjct: 276 VTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMAT 335
Query: 357 LESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGV 416
++ +LGF+ +E +++ ++ AV+ +GN+ K+++ +QA A K L L
Sbjct: 336 DSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNS 395
Query: 417 TDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSP 475
D ++L PR+KVG ++V K QT +Q A+ ALAKA YE++F W+V R+N+ LD + P
Sbjct: 396 ADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQP 455
Query: 476 RQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTF 535
RQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F
Sbjct: 456 RQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEF 513
Query: 536 LDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPR 594
+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G FQ+P+
Sbjct: 514 IDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPK 570
Query: 595 HLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGG 652
+ +A FS++HYAG VDY WL KN DPLN+ V L +S + A
Sbjct: 571 PAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA--------- 621
Query: 653 FQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVG 712
F F G+ G G G GG+ + F+TV
Sbjct: 622 ---FLFSGAQTAEAEG--------------------------GGGKKGGKKKGSSFQTVS 652
Query: 713 QLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQG 772
L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEGIRICR+G
Sbjct: 653 ALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKG 712
Query: 773 FPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAG 831
FP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++E+D Y+ G +K+FF+AG
Sbjct: 713 FPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAG 772
Query: 832 VLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQ 891
+L LEE RD K+ +I QA RG+L R F+K +++ ++ +Q N A++ ++HW
Sbjct: 773 LLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWP 832
Query: 892 WWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLA 951
W +L+ K+KPLL+ ++ + +E +K +E ++ + EL+ ++ L +E+ L
Sbjct: 833 WMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQ 892
Query: 952 EQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQ 1011
Q++AEA+ A+AEE +L K +LE + E+ R +EEE + ++ +K++L+
Sbjct: 893 LQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 952
Query: 1012 ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSS 1071
EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++ +
Sbjct: 953 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012
Query: 1072 QAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVE 1131
EE+KV +L K + K E + D+E L +E+K +LE+ KR+L+G+ QE ++
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072
Query: 1132 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
+ ++L +L +KE E+ + EDE QL K ++E QA + E +E++E+ER +
Sbjct: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERAS 1132
Query: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE T HEA
Sbjct: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEAT 1192
Query: 1252 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1311
LR++H ++ EL EQ++ +R K EK + L+ E+++L + + ++ A+ E+
Sbjct: 1193 AAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKM 1252
Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
R LE QL E++ + + +R E + + R E S L+E ++ +LS+ +
Sbjct: 1253 CRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAF 1312
Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1431
Q+ + + L+EET+AK L +++ + LREQ EEE A+ R + A +++
Sbjct: 1313 TQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEV 1372
Query: 1432 SEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDA 1490
++WR + E +A E EEA+++ A+ + + + LE+ ++RLQ E++D
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDL 1432
Query: 1491 TMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRAL 1550
+D+E+ L+KKQR FD++LAE K E E ++ E R + A
Sbjct: 1433 MIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAY 1492
Query: 1551 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1610
EE + E L+R+N+ L+ E+ L + GK +HELE+ + + ++L+ + E E
Sbjct: 1493 EESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAE 1552
Query: 1611 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1670
L E LR+++ + +K++ +R + +DE ++ +R + + + D E + R
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSR 1612
Query: 1671 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
A+ +KK+EG+L E++ Q+ A + EA++ LR Q +K+ +++ ++++
Sbjct: 1613 NDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLK 1672
Query: 1731 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1790
Q E+R ++AEV L+ L ++R R+ A+Q+ + ++ V + +++ K+
Sbjct: 1673 EQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKK 1732
Query: 1791 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850
+LE + Q++ E+E+ + ++ +K + + EL E+ SA E ++ +E+
Sbjct: 1733 KLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1792
Query: 1851 QIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 1910
+++L+ RL E + A K I LE+++ + E ++E E + + + K +R+ E+R+K
Sbjct: 1793 TVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVK 1852
Query: 1911 EVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTE 1970
E+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ A R+LQ ELE+ E
Sbjct: 1853 ELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKE 1912
Query: 1971 SAESMNREVTTLRNRLR 1987
A+ +V LR + R
Sbjct: 1913 RADIAESQVNKLRVKSR 1929
Score = 241 bits (615), Expect = 5e-63
Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%)
Query: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
Query: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 891 LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
Query: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
++ H Q L +L Q+E+ + KT+L E +V +L L + + E+ +R+L
Sbjct: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
Query: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
E L+ Q D E + + EKL++ + E+ N+ G + + ++ I+L K++ +A++
Sbjct: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119
Query: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 1436 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1495
R EE EA A R+ ++ +AE E +D L+R +++L++E + M++
Sbjct: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
Query: 1496 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1548
+ T+ K + F+++ L ++ + + EE++R E ++AR + +R
Sbjct: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
Query: 1549 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
L+E+ +L R +A ++E L ++ K+ L A + A + LR Q E
Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
Query: 1609 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1668
++ + + V +T++E D R E EE +++LA++L+DAE +
Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
Query: 1669 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1728
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
Query: 1729 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1788
++R L ++ + L R + QQ+ ++ +++A G + +
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
Query: 1789 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1848
K+QL+ +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591
Query: 1849 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1906
++ + DA R+R+ +E L + E QL R+ + + +R +
Sbjct: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651
Query: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1966
LK+ L +++ R D L++QL R ++ ++EE R + GR+ ++EL
Sbjct: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711
Query: 1967 DVTESAESMNREVTTLRNRLRR 1988
D +E + ++ + T+L N ++
Sbjct: 1712 DASERVQLLHTQNTSLINTKKK 1733
Score = 181 bits (458), Expect = 8e-45
Identities = 204/949 (21%), Positives = 411/949 (43%), Gaps = 98/949 (10%)
Query: 897 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947
TK K LQ Q + LQ ++ + + + + ++V +L+G + Q LE +
Sbjct: 997 TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056
Query: 948 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007
+L L+ E + E + +L + ++ E +S L+ ++ +E+ + Q+Q + K LQ
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116
Query: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1056
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176
Query: 1057 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1098
K R+ LE+ + + AA E E++ SL +++ K E I D+
Sbjct: 1177 KMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLA 1236
Query: 1099 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1158
+ K + EK+ R L+ + SE++ + EQQ+ EL AQ R E + +
Sbjct: 1237 SNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLD 1296
Query: 1159 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1218
++ +QL + + + E + LE E A++ + + + LR + E+ +
Sbjct: 1297 EKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQE 1356
Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
+ Q SK EV + + E + ++E +++ Q L + E +E
Sbjct: 1357 AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCA 1416
Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1338
+ EKT+ L+ EV +L ++ A ++++R + L E + + + + A EA++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQ-AELEASQ 1475
Query: 1339 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1397
K R+ EL V A E+ L +E + + ++ D E + E + L +
Sbjct: 1476 KESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK 1535
Query: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1456
++ E + L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1536 QLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHL 1595
Query: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL--------EQQRQLVST----- 1503
R E++ L + + + R +++++ +L++ + L E R L +T
Sbjct: 1596 RVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILK 1655
Query: 1504 -----LEKKQRKFDQL-----LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1553
L+ R D L + E +A +++A E RA E ER + + L +
Sbjct: 1656 DTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE--QELLDA 1713
Query: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613
E + L QN +L + L + + + ++ + R AE+ A + +EL
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773
Query: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDE 1665
+D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E +
Sbjct: 1774 KKEQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVES 1832
Query: 1666 ERKQRTLAVAARKKLEGELEELKAQ---------------------MASAGQGKEEAVKQ 1704
E+K AV +K E ++EL Q + + + EEA +Q
Sbjct: 1833 EQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQ 1892
Query: 1705 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
A+ ++L E+EE + + ++++ ++ R+K E + EE
Sbjct: 1893 SNVNLAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939
Score = 135 bits (340), Expect = 4e-31
Identities = 170/785 (21%), Positives = 329/785 (41%), Gaps = 120/785 (15%)
Query: 1288 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAEL 1347
E E++ ++ E + + E +R+ LE ++ + D Q ++
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKND--------------LQLQV 895
Query: 1348 ENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLR 1407
+ + AL +AE + +L K EA++ + E ++E L ++ R +E E + L+
Sbjct: 896 QAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955
Query: 1408 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE--AGEEARRRAAREAEALT-Q 1464
+ +++ + +E + ++ + EE AG E A ++A +EA T
Sbjct: 956 KDIDDLELTLAKVEKEKHATENKV---KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012
Query: 1465 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1524
L + + V+ L + + +L+Q++DD LEQ+++L LE+ +RK + L + + +
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072
Query: 1525 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1584
++++ + +++E +L +E+EQ +L+++ + L+A +E L ++++
Sbjct: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEEL---EEEI--- 1126
Query: 1585 VHELERACRV-AEQAANDLRAQVTELEDELT---AAEDAKLRLEVTVQALKTQHERDLQG 1640
E ERA R AE+ +DL ++ E+ + L A A++ + +A + RDL+
Sbjct: 1127 --EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 1641 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1700
E L K+ D+ E E Q ++KLE E ELK ++ E
Sbjct: 1185 STLQHEATAAALRKKHADSVAELGE---QIDSLQRVKQKLEKEKSELKMEINDLASNMET 1241
Query: 1701 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1760
K + + L ++ E +T EE ++ + L A+ RL E S
Sbjct: 1242 VSKAKANFEKMCRTLEDQLSEIKTKEEE-------QQRLINELSAQKARLHTE---SGEF 1291
Query: 1761 RRQAQQDRDEMADEVANGNLSKAAILEE-KRQLEGRLGQ-----------------LEEE 1802
RQ + +D M +++ G + +EE KRQLE L E+
Sbjct: 1292 SRQLDE-KDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQ 1350
Query: 1803 LEEEQ------------SNSEL-----------------LNDRYRKLLLQVESLTTELSA 1833
EEEQ +NSE+ L + +KL +++ + A
Sbjct: 1351 YEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1410
Query: 1834 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKM------TIAALESKLAQAEEQ 1887
S A E +Q+L+ ++++L + +A A K +A + K + + +
Sbjct: 1411 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE 1470
Query: 1888 LEQETRE-RILSGKL----------------VRRAEKRLKEVVLQVEEERRVADQLRDQL 1930
LE +E R LS +L ++R K L++ + + E+ + +L
Sbjct: 1471 LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHEL 1530
Query: 1931 EKGNLRV----KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
EK ++ +L+ LEEAE + R+Q EL V + E ++L
Sbjct: 1531 EKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQL 1590
Query: 1987 RRGPL 1991
+R L
Sbjct: 1591 KRNHL 1595
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 1245 bits (3221), Expect = 0.0
Identities = 712/1920 (37%), Positives = 1118/1920 (58%), Gaps = 77/1920 (4%)
Query: 87 RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146
R L L DQ+ MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N
Sbjct: 68 RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127
Query: 147 PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206
PYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT
Sbjct: 128 PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187
Query: 207 NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266
NTK+VIQY A +A + +KE P + G LE Q++QANP+LEAFGNAKTV+NDN
Sbjct: 188 NTKRVIQYFATIAVTGDKKKETQ-PGKMQ----GTLEDQIIQANPLLEAFGNAKTVRNDN 242
Query: 267 SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326
SSRFGKFIRI+F G + A+IETYLLEKSR Q E S+HIFYQ++ +L D
Sbjct: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-ID 301
Query: 327 LLLEPCSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSA 379
LLL + + F P S G+ + E T ++ +LGFS EE + + ++ A
Sbjct: 302 LLLISTNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGA 357
Query: 380 VLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQ 439
V+ +GN+ K+++ +QA A K L+GL + + L PR+KVG +YV K Q
Sbjct: 358 VMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQ 417
Query: 440 TKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSF 498
+Q ++ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS
Sbjct: 418 NVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSL 475
Query: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGL 558
EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL CI+LIE+P G+
Sbjct: 476 EQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GI 532
Query: 559 LALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKA 615
++L+EEC FPKATD SF K+ Q G FQ+P+ + +A+ FS++HYAG VDY
Sbjct: 533 FSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNI 592
Query: 616 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSS 675
WL KN DPLN+ V L +S+ +L + ++ + G
Sbjct: 593 AGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----------------------- 629
Query: 676 AISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 735
+ G GG+ + F+TV +++E+L++LM L +T+P FVR
Sbjct: 630 --------------ETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVR 675
Query: 736 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 795
C++PN K G ++ LV+ QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY IL +AIP
Sbjct: 676 CLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIP 735
Query: 796 KG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAA 854
+G F+D K A EK++ ++++D +R G +K+FF+AG+L LEE RD K+ ++ S QA
Sbjct: 736 EGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAV 795
Query: 855 ARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQA 914
RGYL R F+K +++ ++ +Q N +++ ++HW W LF K+KPLL+ ++ +
Sbjct: 796 CRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMAT 855
Query: 915 RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAAR 974
++ ++ +E +S EL+ ++ L +E+ L Q+++E E +AEE L
Sbjct: 856 MKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKS 915
Query: 975 KQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTT 1034
K LE V EL R+ EEEE + ++ +K+ L+ L+ ++ E K++ EK T
Sbjct: 916 KILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHAT 975
Query: 1035 EAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI 1094
E K+K E++ LE+ SKL+KE+K L++ + EE+KV L K+ K E
Sbjct: 976 ENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQT 1035
Query: 1095 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1154
D+E L +E+K R +LE+ KR+L+G+ QE +++ + +++ +L +KE EL
Sbjct: 1036 DDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQ 1095
Query: 1155 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1214
A+ +DE Q K ++E QA + E +E++E+E R K EKQR DL ELE + LE
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155
Query: 1215 DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQAR 1274
+ +T+AQ E+ KRE E ++++ LEE T HEA LR++ ++ EL EQ++ +
Sbjct: 1156 EASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQ 1215
Query: 1275 RGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 1334
R K EK + L+ E+ ++ + + +L ++ E+ R +E Q E+ +A D ++ +
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI--KAKDEQQTQL 1273
Query: 1335 EAAEKLQRAQAELEN--VSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLAL 1392
+Q+A+ + +N +S + E ES +L+K + QL + + ++EET+AK A+
Sbjct: 1274 IHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333
Query: 1393 GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEA 1451
+++ + LREQ EEE A+ R L A +++++WR + E +A E EEA
Sbjct: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1393
Query: 1452 RRRAAREAEALTQRLAEKTETVD----RLERGRRRLQQELDDATMDLEQQRQLVSTLEKK 1507
+++ A+ Q E TET + LE+ ++RLQ E++D DLE+ +TL+KK
Sbjct: 1394 KKKLAQR----LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKK 1449
Query: 1508 QRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL 1567
QR FD++LAE K + + E E A+ E R + A EE + E L R+N+ L
Sbjct: 1450 QRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNL 1509
Query: 1568 RAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV 1627
+ E+ L + GK++ E E+ ++ EQ +DL+ + E+E L E LR+++ +
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569
Query: 1628 QALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEEL 1687
+K++ +R + +DE E+ +R + + D E + R A+ +KK+EG+L E+
Sbjct: 1570 SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEM 1629
Query: 1688 KAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEV 1747
+ Q+ + + E K LR +Q Q+K+ +++ S E++ Q E+R L E+
Sbjct: 1630 EIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEEL 1689
Query: 1748 LRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
++ L ++R RR ++Q+ + +D V + +++ K++LE + Q + E+E
Sbjct: 1690 EEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSI 1749
Query: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
S ++ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A
Sbjct: 1750 QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809
Query: 1868 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLR 1927
K I LE+++ + E +L+ E + + K + E+++KE+ Q EE+ + +L+
Sbjct: 1810 KGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQ 1869
Query: 1928 DQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
D ++K +VK KRQ EEAEE+A+ + RR+Q ELE+ E A+ +V LR + R
Sbjct: 1870 DLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929
Score = 214 bits (546), Expect = 5e-55
Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%)
Query: 1085 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142
K++ ++ A+ E KE E+ ++EL + + R EL+E+MV Q +L+ Q
Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894
Query: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202
+ + E L A R E L+KS +A + E E LE E ++ ++R+L
Sbjct: 895 VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947
Query: 1203 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1259
++ +L+ +++D TL ++ + + ++E LEE + L++ H
Sbjct: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007
Query: 1260 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1319
Q L +L Q+E+ + K LE + +L L + R + E+ +R+LE L
Sbjct: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063
Query: 1320 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1379
+ Q D E + + EKL++ + EL + +++ + +++ K++ +A++ + +
Sbjct: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123
Query: 1380 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1439
E ++ E + + + + E + E+LEE + A + +A+ + RR E
Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499
E EA R+ ++ +AE E +D L+R +++L++E + M+++
Sbjct: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237
Query: 1500 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1552
+ L K + ++ E++ + ++A +E++ + L L+ +EE
Sbjct: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297
Query: 1553 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1612
++ +L + +AL +LE L ++ K+ + + A + + + LR Q E ++
Sbjct: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357
Query: 1613 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1672
+ A + V +T++E D R E EE +++LA++L++AE + +
Sbjct: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417
Query: 1673 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1732
+++L+GE+E+L + + K+ R + E ++++E++ E +
Sbjct: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477
Query: 1733 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1792
+R L + + ++L R + Q++ ++ +++A + + K+ +
Sbjct: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537
Query: 1793 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1852
E L+ LEE + + E + ++ L++ + +EL +R K E +QL+R
Sbjct: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594
Query: 1853 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1909
Q L DA R+R+ +E L + E QL R+ + K +R + +L
Sbjct: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654
Query: 1910 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1969
K+ L +++ R + L++QL R L +LEE + + + RR ++EL D +
Sbjct: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714
Query: 1970 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
+ + ++ + T+L N ++ ++E ++E+A++A
Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762
Score = 139 bits (349), Expect = 4e-32
Identities = 181/852 (21%), Positives = 343/852 (40%), Gaps = 195/852 (22%)
Query: 912 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL 971
LQA+ + ++V LQ Q +++ ELQ R+ +LEEE + AE L A+ E+ R L
Sbjct: 1094 LQAKIDD-EQVHSLQFQ--KKIKELQARIEELEEE-------IEAEHTLRAKIEKQRSDL 1143
Query: 972 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE----------- 1020
A +E+ + E + E +++ + E +++++ ++E EA
Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADS 1203
Query: 1021 -----------EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1069
+ +QKL+ EK + ++ ++ L S + + + +ED+ +E
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI 1263
Query: 1070 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1129
++ ++ + + LN + + + ++ R+ ++E +L K K+ L + EL+ QM
Sbjct: 1264 KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM 1323
Query: 1130 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESER 1189
E+ + + L + + E+E A+A+L ++L +A + +A+ + E++
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDA 1383
Query: 1190 VARTKA-EKQRRDLGEELEA---------------------LRGELEDTLD----STNAQ 1223
+ RT+ E+ ++ L + L+ L+GE+ED + S A
Sbjct: 1384 IQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTAC 1443
Query: 1224 QELRSKR---EQEVTELKKTLEEETRIHEAAVQELRQ------RHGQALGELAEQLEQAR 1274
L K+ ++ + E K+ L+E EAA +E R + A E+ +QLE R
Sbjct: 1444 ATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLR 1503
Query: 1275 R-------------------GKGAWE--KTRLALEAEVSELRAELSSLQTARQEGEQRRR 1313
R GK E KT+ +E E S+L+ L ++ + + E +
Sbjct: 1504 RENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKIL 1563
Query: 1314 RLELQLQEVQGRAGDGERARAEAAEKL----QRAQAELENV------------------S 1351
R++L+L +V+ + E E+L QRA L++V
Sbjct: 1564 RVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKME 1623
Query: 1352 GALNEAE-------SKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
G LNE E + K L + + QL D+Q L + R+ L ++ +E
Sbjct: 1624 GDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNG 1683
Query: 1405 GLREQLEEEAAARERAGRELQTAQAQLSE-----------------WRRRQEEEAGALEA 1447
L E+LEE A E+ R + ++ +L + +++ E + +A
Sbjct: 1684 LLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA 1743
Query: 1448 -----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 1496
EE ++A +A + + L ++ +T LER ++ L+Q + D L++
Sbjct: 1744 EVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803
Query: 1497 QRQL--------VSTLEKKQRKFDQLL---------------------------AEE--- 1518
QL + LE + R+ + L AEE
Sbjct: 1804 AEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHK 1863
Query: 1519 ------------KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRA 1566
+A V + E AE + + +R + LEE E + E Q
Sbjct: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNK 1923
Query: 1567 LRAELEALLSSK 1578
LRA+ + S K
Sbjct: 1924 LRAKSRDVGSQK 1935
Score = 116 bits (291), Expect = 2e-25
Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%)
Query: 894 RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 943
R+ K + Q+T+ + L + +EL++ E + QS+R +L Q
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351
Query: 944 EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 997
EEE+ AE RA ++ +E + R + R +ELE +L R+ E EE +
Sbjct: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411
Query: 998 -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1047
++ K+RLQ +++L LE A +++ +KV E K K E L
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471
Query: 1048 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1107
Q KE + L L + + E +++++L + + I+D+ +++ + K
Sbjct: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526
Query: 1108 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1167
QE EK K+ ++ E S+LQ + E + E +++ R + EL + + + + +
Sbjct: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586
Query: 1168 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1227
++ L+ AEA L+S A ++ L +++E E+E L +N Q
Sbjct: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643
Query: 1228 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1281
K + V +LK + L++ R +E ++L +R G L E+LE+ + E
Sbjct: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700
Query: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
+TR E E+ + + L + +++LE + + Q + + A EK +
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760
Query: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1400
+A + ++ L + + + L + + E + D Q L E + L G + ++ +E
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
Query: 1401 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1460
L +L+ E A + + ++ E + EE+ + ++ + + +
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880
Query: 1461 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518
+ ++ E E + RR+Q EL++A + V+ L K R EE
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 1141 bits (2952), Expect = 0.0
Identities = 681/1947 (34%), Positives = 1081/1947 (55%), Gaps = 72/1947 (3%)
Query: 53 RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112
++ W+P + + A ++ ++ + G L + D+IQ+MNPP+F EDMA
Sbjct: 51 KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
Query: 113 LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172
LT LNEASVLH L+ RY +IYTYSGLFCV INPYK LP+Y + ++ Y+GK+R E PP
Sbjct: 111 LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
Query: 173 HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA 232
H++AV A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+ + RK+ G
Sbjct: 171 HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228
Query: 233 SVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 292
LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F G + +I+ Y
Sbjct: 229 ---------LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIY 279
Query: 293 LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERE 351
LLEKSR I Q E ++HIFYQ+L G E L+ S + F + G + + E
Sbjct: 280 LLEKSRVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAE 339
Query: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
T +++ +LGF +E ++ A++ FGN+ K++ +Q A K L
Sbjct: 340 ELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFL 399
Query: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
+G+ ++ + L+ PRIKVG +YV + QT EQ A+ AL+K+ YER+F+WLV R+NRAL
Sbjct: 400 MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459
Query: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
D + RQ F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN MFVLEQEEY++E
Sbjct: 460 DAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKES 517
Query: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---H 587
I W + FGLDLQ CIDLIE+P G+L++L+EEC FPKATD +F K+ G H
Sbjct: 518 IEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVH 574
Query: 588 PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
+ +P + +A F ++HYAG V Y + WL KN D LN+ V A+ +S++RL A +++
Sbjct: 575 LQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFE 634
Query: 648 DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
+ ++ + P G +R A
Sbjct: 635 N---------YMSTDSAIPFGEKKRKKGA------------------------------S 655
Query: 708 FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 767
F+TV L+KE+L++LM L +T P FVRCI PN K G L+P LVL QLRCNGVLEG R
Sbjct: 656 FQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTR 715
Query: 768 ICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKI 826
ICR+GFPNR+ + +F+QRY IL P PK F+ ++A E+++ +LE+D YR G +K+
Sbjct: 716 ICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKV 775
Query: 827 FFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLK 886
FF+AG L QLE RD +++ + FQA A+G L R FQK +++ AL ++Q N A++
Sbjct: 776 FFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMA 835
Query: 887 LRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEE 946
+++W W RLF K+KPL++ + E + +E ++Q+ ++S + EL+ + L +E
Sbjct: 836 VKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQE 895
Query: 947 RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006
+ L QL+AE E A EE L K +LE V EL RV EEEE + ++ ++L
Sbjct: 896 KNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKL 955
Query: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066
+ EL+ ++ E K + EK TTE K+K E++ L + SKL++ K++++
Sbjct: 956 EDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAH 1015
Query: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQ 1126
+ EEEK+ SL+K LK E + ++E L +E K R E+ +L+G +
Sbjct: 1016 QQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNR 1075
Query: 1127 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1186
E M + L +L +KE EL ++ E+E G AQL K+++E Q + + +E LE
Sbjct: 1076 ESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLE 1135
Query: 1187 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETR 1246
+ER R K E++R DL ++L L LE+ S+ AQ E+ K+E + +L + +EE T
Sbjct: 1136 AERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATL 1195
Query: 1247 IHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQ 1306
E L++RH +L EL Q+E ++ K EK + L+ EV +L + + A+
Sbjct: 1196 HFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKA 1255
Query: 1307 EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366
E+ E +L E + + + A + + +E L E E+ +LS+
Sbjct: 1256 NAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR 1315
Query: 1367 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQT 1426
E S+ Q+ D + L++ET+++ AL ++ + + LREQ EEE + R L
Sbjct: 1316 EKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSK 1375
Query: 1427 AQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1485
A++ +WR + E E E+A++ A + + + LER R +LQ
Sbjct: 1376 VNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435
Query: 1486 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545
EL DA DL + R + L++KQ + + LA+ K E +A + ++E +ALS
Sbjct: 1436 ELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQK-----HEESQALLDASQKEVQALS 1490
Query: 1546 -----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1600
L EE +E L R+N+ L+ E+ L + + K++ E+E+ ++ E+
Sbjct: 1491 TELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKT 1550
Query: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660
+++ + E E L E L ++ + K + ER L +DE E RR+ + +
Sbjct: 1551 EVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQ 1610
Query: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720
D E K R +KK+E +L E++ Q++ A + EA K L ++Q Q+K+L +++
Sbjct: 1611 SSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLD 1670
Query: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780
++ ++ Q +E+R L++E+ L+ ++R RR ++++ E + +
Sbjct: 1671 DSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYT 1730
Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840
++L +K++LE + ++++E EE + ++ +K ++ +L+ EL ++ A
Sbjct: 1731 QNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAH 1790
Query: 1841 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGK 1900
E R+ +E+ I +L+ RL E + A + I LES++ + E +LE E R + +
Sbjct: 1791 LERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQR 1850
Query: 1901 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1960
RR E+ +KE+ Q EE+++ +++ Q++K L+V+ K+Q+E AE +A++ + ++
Sbjct: 1851 GARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKK 1910
Query: 1961 LQRELEDVTESAESMNREVTTLRNRLR 1987
Q EL +V E AE +V L+ + R
Sbjct: 1911 QQHELNEVKERAEVAESQVNKLKIKAR 1937
Score = 189 bits (479), Expect = 3e-47
Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%)
Query: 1028 QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1084
QLE + E K F L KL K +K+LE+R A Q VK+
Sbjct: 784 QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840
Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
+RL ++ + +E G +E L+K + + + EL+ + V Q +L
Sbjct: 841 WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900
Query: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
QL ++E L + E L+KS + +A + E E +E E ++ + R
Sbjct: 901 LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
Query: 1201 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257
L +E L+ E++D L + ++ + + +TE + L E+ A + +++
Sbjct: 954 KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
Query: 1258 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1317
H Q L +L + E+ + K L LE +V EL L + AR E+ +LE
Sbjct: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
Query: 1318 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1377
L+ + + E ++ AE+L++ + EL ++ + + +L K + + Q+ D
Sbjct: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
Query: 1378 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1434
+E L+ E TRAK+ R RA + + A L E+LEE + + + + +
Sbjct: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186
Query: 1435 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1493
R EE E + ++ ++ A + E + V +LE+ + LQ E+DD
Sbjct: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246
Query: 1494 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1553
+EQ + + EK +++ L E A + + + A+ + + + R LEE+
Sbjct: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306
Query: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613
+ +L R+ ++E L + KS L A + A++ + LR Q E ++
Sbjct: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366
Query: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
++ + + ++E ++ R E E+ +++LA +L++A +
Sbjct: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426
Query: 1674 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1733
AR +L+ EL + + + A +L + Q Q + + + + EE +
Sbjct: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479
Query: 1734 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1786
S+K ++ L E+L+L +E + + RR+ Q++ + ++V G + +
Sbjct: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539
Query: 1787 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1843
+ K+ +E +++ LEE + E + + L Q+E L + ER S K E+
Sbjct: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597
Query: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1901
R++ + I L+ L D+ A++R ++T +E L + E QL R+ + K
Sbjct: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654
Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
+ + + ++K++ +Q+++ ++ L++Q+ R L+ +LE+ + + GRR
Sbjct: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714
Query: 1962 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
+ EL + TE + T+L ++ ++ R EE V + AEE
Sbjct: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 554 bits (1427), Expect = e-157
Identities = 458/1542 (29%), Positives = 738/1542 (47%), Gaps = 170/1542 (11%)
Query: 56 VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106
VW+P + +A L EG++ ++ L E L P D +QR NP
Sbjct: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70
Query: 107 AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V INPY+QLPIY + ++ Y G+
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
Query: 166 KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225
++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S
Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---- 186
Query: 226 KEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIV 285
S +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+
Sbjct: 187 -----------ASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHII 235
Query: 286 GANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS 345
GAN+ TYLLEKSR + QA DE ++HIFYQL AG +L L + + + G +S
Sbjct: 236 GANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTS 295
Query: 346 --PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDN 402
+ E F++T ++ +LG +S+ ++++++L G++A++ ER+ D ++ P +
Sbjct: 296 IEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQD 355
Query: 403 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 462
CRLLG+ + L ++ + K + +Q A ALAK Y +LF W
Sbjct: 356 VYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGW 415
Query: 463 LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 522
+V +N+AL S +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LE
Sbjct: 416 IVEHINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474
Query: 523 QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 582
QEEY +E IPWT +DF D QPCIDLIE G+L LLDEEC PK TD+++ +K+
Sbjct: 475 QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYD 530
Query: 583 EQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 642
FQ+PR F ++H+A KV+Y ++ +L KN D + + +L S L
Sbjct: 531 RHSSSQHFQKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588
Query: 643 AEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGR 702
A+++ D+ P + PG SS IS PP
Sbjct: 589 ADLFHDDK---------DPVPATTPGKGS--SSKISVRSAR--------------PPMKV 623
Query: 703 PRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGV 762
+ +TVG ++ SL LM TL+ T P +VRCI PN EK +P+ + QLR GV
Sbjct: 624 SNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGV 683
Query: 763 LEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVG 822
LE IRI G+P+R + +F RY +L D K C +++ L DP+ ++ G
Sbjct: 684 LETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELANTDKKAICRSVLENLIKDPDKFQFG 742
Query: 823 QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
++KIFFRAG +A LE+ R K + Q RG+L + K + + A +QR C
Sbjct: 743 RTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK---VKYHRLKGATLTLQRYCR 799
Query: 883 AYLKLR-------------HWQWWRLFTKVKPLLQVTRQDEVLQA--RAQELQKV--QEL 925
+L R + +R+ + +V R V+QA RA +++ Q L
Sbjct: 800 GHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVL 859
Query: 926 QQQSAREVGE-LQGRVAQLEEERARLA--------EQLRAEAELCAEAEETRG--RLAAR 974
+ A + + ++G +A+ +R R A L+A EL A E R L
Sbjct: 860 MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRL 919
Query: 975 KQELELVVSELEARVGEEEE----CSRQMQTEKKRLQQHIQELEAHL-----EAEEGARQ 1025
+E V +L+ ++ E+ + S Q+ ++ L+ L E
Sbjct: 920 NVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSL 979
Query: 1026 KLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
+LQ E + ++++ + +LED + S+E+ L R+A+ + A +++ + LN
Sbjct: 980 RLQEEVESLRTELQRAHSERKILEDAH---SREKDELRKRVADLEQENALLKDEKEQLNN 1036
Query: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQL-- 1143
L + KE ++ELE+ + R L ++ + +QR + LR ++
Sbjct: 1037 QILCQSKD--EFAQNSVKENLMKKELEEERSRY----QNLVKEYSQLEQRYDNLRDEMTI 1090
Query: 1144 ------GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE-DLESERVART--- 1193
R+ Q++L E + + + + + AL + +E LE + T
Sbjct: 1091 IKQTPGHRRNPSNQSSL---ESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFL 1147
Query: 1194 KAEKQRRDLGEELEALRGELE--DTLDSTNAQQE-------LRSKREQEVTELKK-TLEE 1243
K +K+ R+L +E + L+ +LE + DS Q E L + LK+ LE
Sbjct: 1148 KLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELES 1207
Query: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
E + + + ELR+ +A+Q Q G+ + L L+ L+
Sbjct: 1208 ENKKLKNDLNELRK-------AVADQATQNNSSHGSPDSYSLL-----------LNQLKL 1249
Query: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
A +E E R+ E+ + Q + D R AE A++ N +++ ++ I
Sbjct: 1250 AHEELEVRKE--EVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA--IE 1305
Query: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
+ T ++ D L ++ LG + ++ A L QL+ ++ E
Sbjct: 1306 AYHGVCQTNSKTEDWGYLNEDG-----ELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEH 1360
Query: 1424 LQTAQAQLSEWRRRQEE---EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGR 1480
L+ L E +Q++ + L + +E LT + E V++LE+
Sbjct: 1361 LKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNE 1420
Query: 1481 RRLQQELD---DATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1519
R+L+++L DLE + L + K+ Q+ + K
Sbjct: 1421 RKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462
Score = 53.1 bits (126), Expect = 3e-06
Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%)
Query: 1374 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1433
++ A++ Q RA + + + RAM + +E +A T Q +
Sbjct: 824 RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873
Query: 1434 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1489
W R+ +A + +A RE +AL A E + RL G ++ ++
Sbjct: 874 WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929
Query: 1490 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1549
+++Q + TL ++ L+ + VE ++ ++ SL R
Sbjct: 930 LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981
Query: 1550 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1609
EE + R EL+R + + +A KD++ K V +LE+ + + L Q+
Sbjct: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038
Query: 1610 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1669
L ++D + V +K + E + R + L K+ E D R +
Sbjct: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087
Query: 1670 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1729
T+ K+ G Q + ++ ++ ++VEE + +
Sbjct: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141
Query: 1730 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1780
+ + +KR++ LE E +LQ E+ D + QA+ D D AD +A +L
Sbjct: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200
Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1837
+ + E ++L+ L +L + + ++ Q+NS + D Y LL Q++ EL +
Sbjct: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
Query: 1838 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1891
+ Q + + L GR E + AR+ +H A+E+ + + E
Sbjct: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318
Query: 1892 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1951
+ + A + LK+V R + QL+ Q + V+ LK QLE +EE
Sbjct: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372
Query: 1952 SRAQ 1955
+ Q
Sbjct: 1373 DKQQ 1376
Score = 47.8 bits (112), Expect = 1e-04
Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%)
Query: 1106 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
K R+EL+ L R++ S+E L+ V + + +L+ ++ + +E +
Sbjct: 898 KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943
Query: 1165 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
L + L + E L+ E V ++ E L EE+E+LR EL+
Sbjct: 944 --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
Query: 1223 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1282
++ S+ + E+ + LE+E + + E Q + Q L + ++ Q + +K
Sbjct: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058
Query: 1283 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1342
E+ E R+ +L + EQR L ++ ++ G
Sbjct: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101
Query: 1343 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1398
N S +++ +I S E+ TE L +E+ E+ L L RVR
Sbjct: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155
Query: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1458
+E E L+ QLE+ R ++ + QA+ + + A L R+ E
Sbjct: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208
Query: 1459 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518
+ L L E + V D ++ L Q + LE ++ + L +
Sbjct: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268
Query: 1519 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1574
+A ++ R E A S E+ + + +E + + +
Sbjct: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322
Query: 1575 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1619
L+ ++G + L++ R+ E + L+AQ+ L++E+ +
Sbjct: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382
Query: 1620 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1671
+ ++E VQ + T DL+ E E+ R+L KQL+ + + +
Sbjct: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442
Query: 1672 LAVAARKKLE 1681
LA + RK+ E
Sbjct: 1443 LAQSERKRHE 1452
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 549 bits (1415), Expect = e-156
Identities = 446/1446 (30%), Positives = 696/1446 (48%), Gaps = 164/1446 (11%)
Query: 50 WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103
+T VW+P +++A + + G++ + L E G L P NP
Sbjct: 7 YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65
Query: 104 FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162
D+ L+ L+E +VLHNLR R+ S LIYTYSG+ V +NPYKQLPIY +AI+ Y
Sbjct: 66 LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125
Query: 163 RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222
G+ ++ PH++AV E AY+ M ++ +QSI+ +GESGAGKT + + ++Y A V+ S
Sbjct: 126 SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185
Query: 223 KGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAG 282
S +E ++L +NPI EA GNAKT +NDNSSRFGK+ I+FD
Sbjct: 186 ---------------SNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQN 230
Query: 283 YIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGP 342
I+GAN+ TYLLEKSR + Q+++E ++HIFYQL A + L L + + G
Sbjct: 231 QIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGG 290
Query: 343 SS--SPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMP 400
++ +R ET ++ +LGF + + + ++++A+L GN+ + N +
Sbjct: 291 NTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE 350
Query: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLF 460
D++ + C LLGL ++ L +I + V K T+ QA A +ALAK Y LF
Sbjct: 351 DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLF 410
Query: 461 RWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFV 520
++V R+N+AL S +Q +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN +F
Sbjct: 411 DFIVERINQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFK 469
Query: 521 LEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKV 580
LEQEEY +E IPWT +DF D QP IDLIE G+L LLDEEC P TD+++++K+
Sbjct: 470 LEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKL 525
Query: 581 AQE-QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639
+P F++PR F + H+A KV+YK +L KN D + D + +L S
Sbjct: 526 YNNFVNRNPLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKF 583
Query: 640 RLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPP 699
L A +++ PPSP GS SA +QV
Sbjct: 584 HLCANFFQE-----------NPTPPSPFGSMITVKSA------------KQVI------- 613
Query: 700 GGRPRRGMFR-TVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLR 758
+P FR TVG ++ SL LM TL+ T P +VRCI PN EK + + + ++ QLR
Sbjct: 614 --KPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLR 671
Query: 759 CNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNL 818
GVLE IRI Q +P+R + EF RY IL F D K+ C+ ++ L D N
Sbjct: 672 ACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKKEVCKVVLHRLIQDSNQ 730
Query: 819 YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQ--------- 869
Y+ G++KIFFRAG +A LE+ R K+ V Q RG+L R+ F + ++
Sbjct: 731 YQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYF 790
Query: 870 --QQS--------------ALRVMQRNCAAYLKLRHWQWWRLFTKV-----KPLLQVTRQ 908
QQ+ A ++Q++C YL +Q R+ T + L R
Sbjct: 791 RGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRY 850
Query: 909 DEVLQA-RAQELQKVQE---------------LQQQSAREVGELQGRVAQLEEERARLAE 952
++L+ +A LQK L Q V LQ ++ +E L E
Sbjct: 851 RKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVE 910
Query: 953 QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK--RLQQHI 1010
+L + A L A E +K E EL + R EE+ + E+K +LQ+H
Sbjct: 911 KLTSLAALRAGDVE-----KIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHN 965
Query: 1011 QELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED----RL 1066
ELE E + +L+L++ T E K +K + L D K ++R LLE +
Sbjct: 966 SELETQKE-----QIQLKLQEKTEELK-EKMDNLTKQLFDDVQKEERQRMLLEKSFELKT 1019
Query: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIAD---MEDRLRKEEKGRQELEKLKRRLDGESS 1123
++ Q +E++K+L +++ + + D L+ E + K + E
Sbjct: 1020 QDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079
Query: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL----LKSLREAQAALA 1179
LQ Q ++ ++ + + ++ K E+ L + D R++L L+ L E L
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNE-DGELW 1138
Query: 1180 EAQEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238
A E L ++ RV + + Q+ +E+EAL ++ QE+ L+
Sbjct: 1139 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHL--------------SQEINHLQ 1184
Query: 1239 KTLEEETRIHEAAVQELRQ--RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296
K EE I+E+ E+ + + + +Q+ + + K E RL +AE + +
Sbjct: 1185 KLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLE-IRLNEQAEKMKGKL 1243
Query: 1297 ELSSLQTARQEGEQRRRRLELQLQ-EVQGRAGDGERARAEAAEKLQRAQAELENVSGALN 1355
E S Q R + E+ +R L+ Q E+ + + + +K+Q Q +++
Sbjct: 1244 EELSNQLHRSQEEEGTQRKALEAQNEIH------TKEKEKLIDKIQEMQEASDHLKKQFE 1297
Query: 1356 EAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA 1415
+E S + D +E L + R L +V+ + ++ G + +
Sbjct: 1298 TESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTL-SKTIGKANDVHSSSG 1356
Query: 1416 ARERAG 1421
+E G
Sbjct: 1357 PKEYLG 1362
Score = 70.1 bits (170), Expect = 2e-11
Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%)
Query: 1508 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1565
+R++ ++L E KA +L+ R + R + LT + Q +++LE QN+
Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903
Query: 1566 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1625
+E L S V ++++ E+AA R + + A E+ +L+
Sbjct: 904 ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
Query: 1626 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1676
L+TQ E+ LQ + E +E+ L KQL D +V+++E +QR L +
Sbjct: 964 HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020
Query: 1677 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1721
K+++ EE+KA Q G + V +L K + E +E+E
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
Query: 1722 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1774
+ + + + SQ RE +++ + ++L E D R + +D + + ++
Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137
Query: 1775 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1820
A L KA +LE E L ++ L +E+ Q ND +
Sbjct: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
Query: 1821 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1880
+V LT+E F + +LE+Q Q+L RL E+ + K + L ++
Sbjct: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249
Query: 1881 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1940
L +++E+ E R+ + + + EK ++++ +++E + +D L+ Q E + VK
Sbjct: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305
Query: 1941 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1982
RQ EASR R L+ EL+ + + +V TL
Sbjct: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
Score = 67.0 bits (162), Expect = 2e-10
Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%)
Query: 1132 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
Q R L QL + + LQ L E + L SL +A E + LE+E
Sbjct: 876 QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933
Query: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
KA RR+ E+ + R +E+ L Q+ S+ E + +++ L+E+T
Sbjct: 934 -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983
Query: 1252 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1311
+EL+++ +L + +++ R + EK+ E + + ++ SL+ + +
Sbjct: 984 -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039
Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
+ +L+ L E + DG +A K + +E E KE+
Sbjct: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081
Query: 1372 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1428
+AQ D ++ +Q E R K++ ++ + +R +L E EL A
Sbjct: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141
Query: 1429 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1487
L + R LE+ ++++ +E EAL ++ ++ ++ L++ L +E
Sbjct: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190
Query: 1488 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1546
+D + + +++ F Q ++E EK + E+AE + E + L
Sbjct: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250
Query: 1547 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1599
R+ EEE R+ LE QN E E L+ ++ ++ L++ Q A
Sbjct: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
Query: 1600 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1630
+ L + +LE+EL + +L+ V+ L
Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
Score = 57.0 bits (136), Expect = 2e-07
Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%)
Query: 904 QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 963
Q+ E ++A E ++Q L + L+ VA+L ++ ++E + L A+
Sbjct: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084
Query: 964 AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 1019
+ + ++K+E+ +SE+ ++ E S ++ + RL +H+ E A
Sbjct: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
Query: 1020 EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1076
EG ++ ++ + +++ +E+++ L + LS+E L+ E + E
Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
Query: 1077 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1133
++ S N + ++ I+++E + + E + ++ EK+K +L+ S++L E+ Q
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
Query: 1134 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
++A E + ++ KE +E+Q A + + +++ + R+ + L DL
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1233
E E + + K+ +D + L G+ D S+ ++ L+ KRE E
Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 536 bits (1381), Expect = e-152
Identities = 464/1502 (30%), Positives = 724/1502 (48%), Gaps = 139/1502 (9%)
Query: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
Query: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
S +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GA
Sbjct: 187 ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
Query: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
N+ TYLLEKSR + QA++E ++HIFYQL A L L ++ + G P
Sbjct: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297
Query: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
+ + T ++ +LG S + + R+++ +L GN+ R+ D T+P
Sbjct: 298 GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356
Query: 406 QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
+ C L+G+ + L ++ + K +K QA A +ALAK Y +LF W+V
Sbjct: 357 LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416
Query: 465 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
+N+AL + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQE
Sbjct: 417 DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
Query: 525 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
EY +E IPWT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+
Sbjct: 476 EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
Query: 585 -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
F++PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++
Sbjct: 532 LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
Query: 644 EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
E+++D+ AISP G ++ P GRP
Sbjct: 590 ELFQDD------------------------EKAISPTSATS-SGRTPLTRTPAKPTKGRP 624
Query: 704 ---RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCN 760
+ +TVG ++ SL LM TL+ T P +VRCI PN K + + + QLR
Sbjct: 625 GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRAC 684
Query: 761 GVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYR 820
GVLE IRI GFP+R +QEF RY +L D KQ C+ +++ L LD + Y+
Sbjct: 685 GVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQ 742
Query: 821 VGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 880
G++KIFFRAG +A LE+ R K+ + Q RG+L R+ K + + A MQR
Sbjct: 743 FGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRY 799
Query: 881 CAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRV 940
Y + R + + TK ++Q + V++ R ++++ + QS L+G +
Sbjct: 800 VRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR-RRYKIRRAATIVLQS-----YLRGFL 852
Query: 941 AQLEEERARLAEQLRAEAELCAEAEETRGRLAAR--KQELELVVSELEARVGEEEECSRQ 998
A R R + LR + + + RG LA K+ + ++ + C R+
Sbjct: 853 A-----RNRYRKILREHKAVIIQ-KRVRGWLARTHYKRSMHAII--------YLQCCFRR 898
Query: 999 M--QTEKKRLQQHIQELEAHLEAEEGARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QN 1052
M + E K+L+ + +E + + G K +QL++ E K E L LE N
Sbjct: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
Query: 1053 SKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE- 1110
S+ K R LE RL Q +EEE KV + L L+ E A + ++ R E+K +E
Sbjct: 959 SETEKLRSDLE-RL-----QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
Query: 1111 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL--- 1167
++ K+ + S L+E+ +Q E L ++ ++ +E+ + + E + +L
Sbjct: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072
Query: 1168 -----LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
++L + L E +DL+ E K + + E E S A
Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIA 1131
Query: 1223 QQELRSKREQEVTELKKTLEEETRIH-EAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
+ E R +E +E K L+ + + V EL Q EL + EQ R K
Sbjct: 1132 EMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSK---- 1187
Query: 1282 KTRLALEAEVSELR-AELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAE 1338
A E E ++R AEL RQE E ++L+ +L E++ + A A
Sbjct: 1188 ----AKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP 1243
Query: 1339 KLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRA 1398
+ +L +VS L+ + + + L +QL +E +Q + S +
Sbjct: 1244 AYRVLMEQLTSVSEELDVRKEEVLIL-------RSQLVSQKEAIQPKDDKNTMTDSTILL 1296
Query: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAR 1457
+ + + ++ + + R L ++QL +R E EA AL + + R
Sbjct: 1297 EDVQKMKDKGEIAQAYIGLKETNRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNR 1353
Query: 1458 EAEALTQ--RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1515
+ + L Q +L + L+ RL E D LE+Q + V L+K+ + F + +
Sbjct: 1354 QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1413
Query: 1516 AE 1517
E
Sbjct: 1414 GE 1415
Score = 66.6 bits (161), Expect = 2e-10
Identities = 129/620 (20%), Positives = 244/620 (39%), Gaps = 106/620 (17%)
Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1337
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
Query: 1338 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1395
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
Query: 1396 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1451
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Query: 1452 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1511
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
Query: 1512 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1571
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
Query: 1572 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK 1631
L + + KS E+ A L Q+T + +EL ++ L L L
Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILR---SQLV 1274
Query: 1632 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE-ERKQRTLAVAARKKLEGELEELKAQ 1690
+Q E +Q +D+ + L D + +D+ E Q + + +L L++Q
Sbjct: 1275 SQKEA-IQPKDDKNTMTDSTIL--LEDVQKMKDKGEIAQAYIGLKETNRL------LESQ 1325
Query: 1691 MASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKG------ 1742
+ S + E + LR +KE E R ++++ +QN + E R++
Sbjct: 1326 LQSQKRSHENEAEALRGEIQSLKE-----ENNR--QQQLLAQNLQLPPEARIEASLQHEI 1378
Query: 1743 --LEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GNLSKAAILEE------ 1788
L E L L E+L D+ R+ ++ A ++ N+S I++E
Sbjct: 1379 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVN 1438
Query: 1789 -KRQLEGRLGQLEEELEEEQ 1807
R+ + G LE + E+EQ
Sbjct: 1439 IPRKEKDFQGMLEYKKEDEQ 1458
Score = 65.1 bits (157), Expect = 7e-10
Identities = 103/551 (18%), Positives = 229/551 (41%), Gaps = 92/551 (16%)
Query: 1464 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
++L + +V+R ++ ++ ++ +++Q + L +K + + E +
Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965
Query: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGK 1583
+E + +E E + R LSL +EE+ + LR +LE S K K
Sbjct: 966 SDLERLQLSEEEAKVATGRVLSL----------QEEIAK----LRKDLEQTRSEK----K 1007
Query: 1584 SVHE-LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRD 1642
+ E +R + EQ ++L+ + T L+ E A + R +Q
Sbjct: 1008 CIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL-----------------NHRIVQQAK 1050
Query: 1643 EAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA------SAGQ 1696
E E ++L ++ + E++ ++ER + + +LE ++LK +M G
Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGH 1110
Query: 1697 GKEEAVKQLRKMQ-------AQMKELWREVEETRTSREEI-FSQNRESEKRLKGLEAEVL 1748
+ ++ + + A+M+++ EE + + S + +KR+ LE E
Sbjct: 1111 KRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ 1170
Query: 1749 RLQEELAASD----RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1804
+Q+EL + R++ + ++ E+ +L + + E ++L+ L +L + L
Sbjct: 1171 VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230
Query: 1805 EEQSNSELLNDR--YRKLLLQVESLTTELSAERS----FSAKAESGRQQLE--------- 1849
E+ + YR L+ Q+ S++ EL + ++ S ++ ++
Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT 1290
Query: 1850 ------RQIQELR--GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
+Q+++ G + + G + +++ + L+S+ E + E R I S K
Sbjct: 1291 DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEA-LRGEIQSLKE 1349
Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLR--------------DQLEKGNLRVKQLKRQLEEA 1947
+++L LQ+ E R+ L+ +QLEK + V++LK+QL+
Sbjct: 1350 ENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVF 1409
Query: 1948 EEEASRAQAGR 1958
++ + G+
Sbjct: 1410 AKKIGELEVGQ 1420
Score = 41.6 bits (96), Expect = 0.008
Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%)
Query: 1792 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1851
+E ++ QL+ +++E+ + + L VE LT + E ++++ E R LER
Sbjct: 925 MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971
Query: 1852 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1911
+L EE+A + +L+ ++A+ + LEQ E+ + R ++ ++
Sbjct: 972 ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022
Query: 1912 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1971
+V ++EE + Q ++ L N R+ Q +++ E E+ + ++L+ +L D
Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077
Query: 1972 AESMNREVTTLRNR 1985
+++ E + L R
Sbjct: 1078 YQNLLNEFSRLEER 1091
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 534 bits (1375), Expect = e-151
Identities = 470/1522 (30%), Positives = 731/1522 (48%), Gaps = 152/1522 (9%)
Query: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
Query: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
S +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GA
Sbjct: 187 ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
Query: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
N+ TYLLEKSR + QA++E ++HIFYQL A L L ++ + G P
Sbjct: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297
Query: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
+ + T ++ +LG S + + R+++ +L GN+ R+ D T+P
Sbjct: 298 GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356
Query: 406 QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
+ C L+G+ + L ++ + K +K QA A +ALAK Y +LF W+V
Sbjct: 357 LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416
Query: 465 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
+N+AL + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQE
Sbjct: 417 DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
Query: 525 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
EY +E IPWT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+
Sbjct: 476 EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
Query: 585 -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
F++PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++
Sbjct: 532 LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
Query: 644 EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
E+++D+ AISP G ++ P GRP
Sbjct: 590 ELFQDD------------------------EKAISPTSATS-SGRTPLTRTPAKPTKGRP 624
Query: 704 ---RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCN 760
+ +TVG ++ SL LM TL+ T P +VRCI PN K + + + QLR
Sbjct: 625 GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRAC 684
Query: 761 GVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYR 820
GVLE IRI GFP+R +QEF RY +L D KQ C+ +++ L LD + Y+
Sbjct: 685 GVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQ 742
Query: 821 VGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 880
G++KIFFRAG +A LE+ R K+ + Q RG+L R+ K + + A MQR
Sbjct: 743 FGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRY 799
Query: 881 CAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRV 940
Y + R + + TK ++Q + V++ R ++++ + QS L+G +
Sbjct: 800 VRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR-RRYKIRRAATIVLQS-----YLRGFL 852
Query: 941 AQLEEERARLAEQLRAEAELCAEAEETRGRLAAR--KQELELVVSELEARVGEEEECSRQ 998
A R R + LR + + + RG LA K+ + ++ + C R+
Sbjct: 853 A-----RNRYRKILREHKAVIIQ-KRVRGWLARTHYKRSMHAII--------YLQCCFRR 898
Query: 999 M--QTEKKRLQQHIQELEAHLEAEEGARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QN 1052
M + E K+L+ + +E + + G K +QL++ E K E L LE N
Sbjct: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
Query: 1053 SKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE- 1110
S+ K R LE RL Q +EEE KV + L L+ E A + ++ R E+K +E
Sbjct: 959 SETEKLRSDLE-RL-----QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
Query: 1111 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL--- 1167
++ K+ + S L+E+ +Q E L ++ ++ +E+ + + E + +L
Sbjct: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072
Query: 1168 -----LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
++L + L E +DL+ E K + + E E S A
Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIA 1131
Query: 1223 QQELRSKREQEVTELKKTLEEETRIH-EAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
+ E R +E +E K L+ + + V EL Q EL + EQ R K
Sbjct: 1132 EMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSK---- 1187
Query: 1282 KTRLALEAEVSELR-AELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAE 1338
A E E ++R AEL RQE E ++L+ +L E++ + A A
Sbjct: 1188 ----AKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP 1243
Query: 1339 KLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ----------------LHDAQELL 1382
+ +L +VS L+ + + + L +L S + L D Q++
Sbjct: 1244 AYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK 1303
Query: 1383 QEETRAKLALG----SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1438
+ A+ +G +R A++ +L ++A R L ++QL +R
Sbjct: 1304 DKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLL---ESQLQSQKRSH 1360
Query: 1439 EEEAGALEAG-EEARRRAAREAEALTQ--RLAEKTETVDRLERGRRRLQQELDDATMDLE 1495
E EA AL + + R+ + L Q +L + L+ RL E D LE
Sbjct: 1361 ENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLE 1420
Query: 1496 QQRQLVSTLEKKQRKFDQLLAE 1517
+Q + V L+K+ + F + + E
Sbjct: 1421 KQDKTVRKLKKQLKVFAKKIGE 1442
Score = 77.4 bits (189), Expect = 1e-13
Identities = 141/606 (23%), Positives = 240/606 (39%), Gaps = 133/606 (21%)
Query: 1369 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1424
S TE D + L E AK+A G RV +++ E A LR+ LE E+ E A R
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
Query: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1484
Q + +S + EE L+ +EA + Q+ E TET+++ +L
Sbjct: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEK------KLV 1061
Query: 1485 QELDDATMDLEQQR----QLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1540
+E +DL +R L++ + + ++D L E V +R ++ E
Sbjct: 1062 EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNE 1121
Query: 1541 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1600
+ + + E E E + + ++ L
Sbjct: 1122 SEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK------------------------ 1157
Query: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660
L+ +VTELE E +D R E V R +A EE R Q+R AE
Sbjct: 1158 -LQKRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAE 1200
Query: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720
+E + ++Q + KKL+ EL EL+ ++ K ++ A +R +
Sbjct: 1201 LEYESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLM 1249
Query: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780
E TS E +E EVL L+ +L + A Q + D++ M D
Sbjct: 1250 EQLTSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI---- 1294
Query: 1781 SKAAILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAE 1834
+LE+ ++++ G + Q L+E +S L LN+ +L L E L A
Sbjct: 1295 ----LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QAN 1346
Query: 1835 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1894
R ++ +S ++ E + + LRG I +L+ E ++
Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQ 1382
Query: 1895 RILSGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEAS 1952
++L+ L E R+ E LQ E R + L +QLEK + V++LK+QL+ ++
Sbjct: 1383 QLLAQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIG 1441
Query: 1953 RAQAGR 1958
+ G+
Sbjct: 1442 ELEVGQ 1447
Score = 63.5 bits (153), Expect = 2e-09
Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%)
Query: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
Query: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1337
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
Query: 1338 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1395
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
Query: 1396 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1451
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Query: 1452 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1511
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
Query: 1512 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1571
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
Query: 1572 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1627
L + + KS E+ A L Q+T + +EL ++ L L +
Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
Query: 1628 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1674
+A++ + ++ D+Q + GE + L + R + ++ E + L +
Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
Query: 1675 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
A + LE +L+ K A A +G+ +++K+ Q Q+ L + ++ +
Sbjct: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395
Query: 1726 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1779
R E Q+ + L E L L E+L D+ R+ ++ A ++ N
Sbjct: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450
Query: 1780 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1807
+S I++E R+ + G LE + E+EQ
Sbjct: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485
Score = 41.6 bits (96), Expect = 0.008
Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%)
Query: 1792 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1851
+E ++ QL+ +++E+ + + L VE LT + E ++++ E R LER
Sbjct: 925 MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971
Query: 1852 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1911
+L EE+A + +L+ ++A+ + LEQ E+ + R ++ ++
Sbjct: 972 ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022
Query: 1912 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1971
+V ++EE + Q ++ L N R+ Q +++ E E+ + ++L+ +L D
Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077
Query: 1972 AESMNREVTTLRNR 1985
+++ E + L R
Sbjct: 1078 YQNLLNEFSRLEER 1091
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 531 bits (1369), Expect = e-150
Identities = 445/1693 (26%), Positives = 793/1693 (46%), Gaps = 189/1693 (11%)
Query: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
Query: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
Query: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
Query: 225 RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
K V + + +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 524 NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
Query: 285 VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
A+I+T LLEK R R+ E +F++FY LL L+ +L L + P +
Sbjct: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
Query: 345 SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
P ++++ F + +++VLG S +E + +++A+ G A K +
Sbjct: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
Query: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
+ AQK LLG + + S A+ + K G +Q++ + Q A
Sbjct: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
Query: 445 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
LE +A Y LF LV +NRAL S S + I+D GF+ + SF
Sbjct: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
Query: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
E+LC NYT ++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
Query: 557 ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
GLL LL+EE P A++ + +E++ G G K Q P H F
Sbjct: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
Query: 603 SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFL 659
+ H G V+Y WL +P N LL S ++ + + FL
Sbjct: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNL------------FL 975
Query: 660 GSFPPSPPGSAERCSSAISPPGVEG--IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKE 717
G GSA S +I+ G+EG + L + +S+ R+ + + K+
Sbjct: 976 GR-----AGSATVLSGSIA--GLEGGSQLALRRATSM---------RKTFTTGMAAVKKK 1019
Query: 718 SL--------SRLMATLSNTNPSFVRCIVPNHEKRAGK---------------------- 747
SL L+ T+ + FV C +P E AG+
Sbjct: 1020 SLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDH 1079
Query: 748 -------LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG--- 797
L+ L+ QLR + +L+ +R+ RQG+P+ ++F EFR+R+++L P+ K
Sbjct: 1080 CEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRN 1139
Query: 798 --FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 855
+D ++A E++++ L+L+ + +G S++FFRAG LA+LEE+RD + + + FQAA
Sbjct: 1140 YIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAAC 1199
Query: 856 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 915
RGYLAR+ F+KR+ Q A+R +Q+N ++ W WW+LFT V+PL++V +E ++ +
Sbjct: 1200 RGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK 1259
Query: 916 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 975
+E+Q+++ +++ +E EL+ +LE + L +L E A + A +
Sbjct: 1260 DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAER 1319
Query: 976 QELELVVSELEARVGEEEECSRQMQTEKKRLQQH--IQELEAHLEAEE---GARQKLQLE 1030
E + EL+ + + +QM+ + + + I+ E + E ++ G +L+ E
Sbjct: 1320 LRAEKEMKELQT---QYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376
Query: 1031 KVT-----TEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
+ T+ ++++ ED L +E QN ++ LE RL + + + E + ++ L K
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLERRLGDLQADSEESQRALQQLKK 1430
Query: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1145
+ A + D + L ++ ELEK +RR D E S+ E+ ++ + E+L+ +
Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490
Query: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205
E + + E++ A + + +A L + + + K +KQ RDL +
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
Query: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
++ EL++ + ++ + + E E+ +++T +E + V+E RQ + L +
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ 1610
Query: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1325
+ QLE+ K + + LE +++ L S Q R++ E +RL L+ +
Sbjct: 1611 MEVQLEEEYEDKQKVLREKRELEGKLATL-----SDQVNRRDFES-EKRLRKDLKRTKAL 1664
Query: 1326 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEE 1385
D + + + ++ E+ + L E+E K + E ++ D + +
Sbjct: 1665 LADAQ-LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 1386 TRAKLALGSRVRAMEAEAAGLREQLEEE-----------AAARERAGREL---QTAQAQL 1431
+AK AL ++ ++ E ++ +LEE+ AA +A R+L QAQL
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1783
Query: 1432 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
E + ++E L+A + + E L Q + +K+ V R E R L+ L+
Sbjct: 1784 EEANKEKQELQEKLQALQS-------QVEFLEQSMVDKS-LVSRQEAKIRELETRLEFER 1835
Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALE 1551
+++ L S L++ K + + AA R E+ +R + + R+ + L R
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA 1895
Query: 1552 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELED 1611
E + ELE +L A ++L + K + +L+ A E +++ + L+D
Sbjct: 1896 EASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE-DEMESDENEDLINSLQD 1954
Query: 1612 ELTAAEDAKLRLE 1624
+T + K +LE
Sbjct: 1955 MVTKYQKRKNKLE 1967
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1411
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1412 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
Query: 1469 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
Query: 1529 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 1589 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
Query: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
Query: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1768
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1658 LKRTKALLADAQ----LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
Query: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1828
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 1829 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1888
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
Query: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1946
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1832 EFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
Query: 1947 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1979
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Score = 157 bits (396), Expect = 1e-37
Identities = 164/804 (20%), Positives = 350/804 (43%), Gaps = 121/804 (15%)
Query: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1227
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1228 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
Query: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1464
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
Query: 1465 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
Query: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1576
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
Query: 1577 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1626
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
Query: 1627 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1680
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
Query: 1681 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1724
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
Query: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1844
+ + + R+G L+ +E+E +D L+ ++ + T+ ++
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEME-----SDENEDLINSLQDMVTKYQKRKNKLEGDSDV 1972
Query: 1845 RQQLERQIQELRGRLGEEDAGARA 1868
+LE ++ ++ L + ++A
Sbjct: 1973 DSELEDRVDGVKSWLSKNKGPSKA 1996
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1616
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
Query: 1617 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
Query: 1674 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1731
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
Query: 1732 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1784
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1843
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
Query: 1844 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
Query: 1962 QRELEDVTESAESMNREVTTLRNRLRR 1988
+ E+ED+ + + + T L +L R
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Score = 109 bits (272), Expect = 3e-23
Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%)
Query: 1428 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1481
+ QLSE + R ++E LE E+ R ++ L R++E T E D G
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 1482 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1537
Q +D E +L + E K Q ++D L + + + +E R AE G
Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1538 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1581
ER R + T+ L++E E + E+E+QN R L L L + ++
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 1582 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1641
+++ +L++ C+ D + + + E + R + + + +R+ R
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 1642 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1699
++ E+ LA+ +++ E K +A +K LE EL+++ +Q +
Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Query: 1700 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1756
+ KQLR ++A++K+ E++E + + + E +R++ ++ + ++E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597
Query: 1757 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1816
+ AR+ Q+ +M ++ K +L EKR+LEG+L L +++ SE R
Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653
Query: 1817 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1876
RK L + ++L + + + R+I +L+ +L E + T AA
Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701
Query: 1877 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1936
+A + +E E + L + +A+ L+E + +++ E+ ++++++LE+
Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754
Query: 1937 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
+ +L ++ + A +ASR A LQ +LE+ + + + ++ L++++
Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804
Score = 59.3 bits (142), Expect = 4e-08
Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%)
Query: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1776
R + E + S E+I +++ E ++ LE E SDR + + E+ DE
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303
Query: 1777 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1836
G S + +L+ + E L E+ E L +Y L Q+E + E+ R
Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352
Query: 1837 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1896
A E+ G + ++DAG R K A E +++L+QE +++
Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397
Query: 1897 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1941
+ + R+ E+RL ++ EE +R QL+ + LE +R +L+
Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Query: 1942 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1994
+ +L +A EEA R + R +LQRE + + A S+ +++ + FT
Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513
Query: 1995 TRTVRQVFRLEEGVASDEEAEEA 2017
+ V L++ ++S E +EA
Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 526 bits (1356), Expect = e-149
Identities = 445/1701 (26%), Positives = 793/1701 (46%), Gaps = 194/1701 (11%)
Query: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
Query: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
Query: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
Query: 225 RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
K V + + +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 524 NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
Query: 285 VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
A+I+T LLEK R R+ E +F++FY LL L+ +L L + P +
Sbjct: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
Query: 345 SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
P ++++ F + +++VLG S +E + +++A+ G A K +
Sbjct: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
Query: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
+ AQK LLG + + S A+ + K G +Q++ + Q A
Sbjct: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
Query: 445 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
LE +A Y LF LV +NRAL S S + I+D GF+ + SF
Sbjct: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
Query: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
E+LC NYT ++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
Query: 557 ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
GLL LL+EE P A++ + +E++ G G K Q P H F
Sbjct: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
Query: 603 SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFL 659
+ H G V+Y WL +P N LL S ++ + + FL
Sbjct: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNL------------FL 975
Query: 660 GSFPPSPPGSAERCSSAISPPGVEG--IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKE 717
G GSA S +I+ G+EG + L + +S+ R+ + + K+
Sbjct: 976 GR-----AGSATVLSGSIA--GLEGGSQLALRRATSM---------RKTFTTGMAAVKKK 1019
Query: 718 SL--------SRLMATLSNTNPSFVRCIVPNHEKRAGK---------------------- 747
SL L+ T+ + FV C +P E AG+
Sbjct: 1020 SLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDH 1079
Query: 748 -------LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG--- 797
L+ L+ QLR + +L+ +R+ RQG+P+ ++F EFR+R+++L P+ K
Sbjct: 1080 CEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRN 1139
Query: 798 --FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 855
+D ++A E++++ L+L+ + +G S++FFRAG LA+LEE+RD + + + FQAA
Sbjct: 1140 YIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAAC 1199
Query: 856 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 915
RGYLAR+ F+KR+ Q A+R +Q+N ++ W WW+LFT V+PL++V +E ++ +
Sbjct: 1200 RGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK 1259
Query: 916 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 975
+E+Q+++ +++ +E EL+ +LE + L +L E A + A +
Sbjct: 1260 DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAER 1319
Query: 976 QELELVVSELEARVGEEEECSRQMQTEKKRLQQH--IQELEAHLEAEE---GARQKLQLE 1030
E + EL+ + + +QM+ + + + I+ E + E ++ G +L+ E
Sbjct: 1320 LRAEKEMKELQT---QYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376
Query: 1031 KVT-----TEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
+ T+ ++++ ED L +E QN ++ LE RL + + + E + ++ L K
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLERRLGDLQADSEESQRALQQLKK 1430
Query: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1145
+ A + D + L ++ ELEK +RR D E S+ E+ ++ + E+L+ +
Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490
Query: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205
E + + E++ A + + +A L + + + K +KQ RDL +
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
Query: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
++ EL++ + ++ + + E E+ +++T +E + V+E RQ + L +
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ 1610
Query: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1325
+ QLE+ K + + LE +++ L S Q R++ E +RL L+ +
Sbjct: 1611 MEVQLEEEYEDKQKVLREKRELEGKLATL-----SDQVNRRDFES-EKRLRKDLKRTKAL 1664
Query: 1326 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEE 1385
D + + + ++ E+ + L E+E K + E ++ D + +
Sbjct: 1665 LADAQ-LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 1386 TRAKLALGSRVRAMEAEAAGLREQLEEE-----------AAARERAGREL---QTAQAQL 1431
+AK AL ++ ++ E ++ +LEE+ AA +A R+L QAQL
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1783
Query: 1432 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
E + ++E L+A + + E L Q + +K+ V R E R L+ L+
Sbjct: 1784 EEANKEKQELQEKLQALQS-------QVEFLEQSMVDKS-LVSRQEAKIRELETRLEFER 1835
Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALE 1551
+++ L S L++ K + + AA R E+ +R + + R+ + L R
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA 1895
Query: 1552 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELED 1611
E + ELE +L A ++L + K + +L+ A + ++ +D + E
Sbjct: 1896 EASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAA--IEDEMESDENEDLINSEG 1953
Query: 1612 ELTAAEDAKLRLEVTVQALKT 1632
+ D LE V +K+
Sbjct: 1954 D----SDVDSELEDRVDGVKS 1970
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1411
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1412 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
Query: 1469 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
Query: 1529 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 1589 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
Query: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
Query: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1768
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
Query: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1828
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 1829 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1888
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
Query: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1946
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
Query: 1947 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1979
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Score = 156 bits (394), Expect = 2e-37
Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)
Query: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1186 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1227
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1228 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
Query: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1464
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
Query: 1465 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
Query: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1576
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
Query: 1577 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1626
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
Query: 1627 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1680
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
Query: 1681 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1724
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
Query: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSE 1811
+ + + R+G L+ +E+E + E
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
Query: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1616
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
Query: 1617 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
Query: 1674 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1731
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
Query: 1732 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1784
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
Query: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1843
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
Query: 1844 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
Query: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
Query: 1962 QRELEDVTESAESMNREVTTLRNRLRR 1988
+ E+ED+ + + + T L +L R
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Score = 109 bits (272), Expect = 3e-23
Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%)
Query: 1428 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1481
+ QLSE + R ++E LE E+ R ++ L R++E T E D G
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 1482 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1537
Q +D E +L + E K Q ++D L + + + +E R AE G
Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1538 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1581
ER R + T+ L++E E + E+E+QN R L L L + ++
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 1582 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1641
+++ +L++ C+ D + + + E + R + + + +R+ R
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 1642 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1699
++ E+ LA+ +++ E K +A +K LE EL+++ +Q +
Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Query: 1700 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1756
+ KQLR ++A++K+ E++E + + + E +R++ ++ + ++E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597
Query: 1757 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1816
+ AR+ Q+ +M ++ K +L EKR+LEG+L L +++ SE R
Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653
Query: 1817 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1876
RK L + ++L + + + R+I +L+ +L E + T AA
Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701
Query: 1877 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1936
+A + +E E + L + +A+ L+E + +++ E+ ++++++LE+
Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754
Query: 1937 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
+ +L ++ + A +ASR A LQ +LE+ + + + ++ L++++
Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804
Score = 59.3 bits (142), Expect = 4e-08
Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%)
Query: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1776
R + E + S E+I +++ E ++ LE E SDR + + E+ DE
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303
Query: 1777 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1836
G S + +L+ + E L E+ E L +Y L Q+E + E+ R
Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352
Query: 1837 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1896
A E+ G + ++DAG R K A E +++L+QE +++
Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397
Query: 1897 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1941
+ + R+ E+RL ++ EE +R QL+ + LE +R +L+
Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Query: 1942 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1994
+ +L +A EEA R + R +LQRE + + A S+ +++ + FT
Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513
Query: 1995 TRTVRQVFRLEEGVASDEEAEEA 2017
+ V L++ ++S E +EA
Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 464 bits (1195), Expect = e-130
Identities = 322/977 (32%), Positives = 514/977 (52%), Gaps = 94/977 (9%)
Query: 91 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ 150
+ ++ M+P +DMA LT L+ S+++NL +RY IYTY G +NPY+
Sbjct: 49 ITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQP 108
Query: 151 LP-IYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTK 209
+ +Y A +E Y + E+PPH++A+ YR + + ++Q IL +GESGAGKTE+TK
Sbjct: 109 IAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTK 168
Query: 210 KVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSR 269
++++L+ ++ E + S V ER +L+++PI+EAFGNAKTV N+NSSR
Sbjct: 169 LILKFLSVISQQSL---ELSLKEKTSCV-----ERAILESSPIMEAFGNAKTVYNNNSSR 220
Query: 270 FGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLL 329
FGKF+++N G I G I YLLEK+R +RQ E ++HIFY LL G + + + L
Sbjct: 221 FGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYL 280
Query: 330 EPCSHYRFLTNG--PSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIA 387
+Y +L ++E F+E + ++ V+ FS EE+ + R+++ +L GNI
Sbjct: 281 STPENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE 340
Query: 388 LKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFA 447
A + TA + LLGL T + AL + + + + +QA +
Sbjct: 341 F---ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDS 397
Query: 448 LEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTN 507
++LA A Y F W++ ++N + + +GILDI GFE F++N FEQ INY N
Sbjct: 398 RDSLAMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYAN 455
Query: 508 EKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECW 567
EKLQ+ FN +F LEQ EY REG+ W +D+ +D C+DLIE+ GLLAL++EE
Sbjct: 456 EKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESH 511
Query: 568 FPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLN 627
FP+ATD + +EK+ + + + +PR + +F V HYAG+V Y L KN D
Sbjct: 512 FPQATDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFR 569
Query: 628 DNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVG 687
D++ LL +S +F F+ E +
Sbjct: 570 DDLLNLLRES-----------------RFDFIYDL-------------------FEHVSS 593
Query: 688 LEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGK 747
+L G RP TV +K+SL LMATLS++NP FVRCI PN +K +
Sbjct: 594 RNNQDTLKCGSKHRRP------TVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQ 647
Query: 748 LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPN-AIPKGFMDGKQACE 806
+ +VL+QLR +G+LE +RI + G+ R FQ+F +RY++L N A+P+ D + C
Sbjct: 648 FDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE---DVRGKCT 704
Query: 807 KMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQK 866
++Q + + +++G++K+F R + +LE+ R+ +V+ + +A G+LAR+ ++K
Sbjct: 705 SLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRK 764
Query: 867 RQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQ 926
+ ++Q+N A+L R R K + +Q AR Q + E +
Sbjct: 765 ---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKR 816
Query: 927 QQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELE 986
+Q ++ E + + + EEER R E+ R EAEL A+ EE RKQ+ ELE
Sbjct: 817 EQEEKKKQEEEEKKKREEEERER--ERERREAELRAQQEE-----ETRKQQ------ELE 863
Query: 987 ARVGEEEECSRQMQTEKKRLQQHIQE-LEAHLEAEEGARQKLQLEKVTTEAKMKKFEE-- 1043
A ++E + EK++ + ++E L E E+ R K Q E TEA ++K +E
Sbjct: 864 ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERR 923
Query: 1044 --DLLLLEDQNSKLSKE 1058
+L LE++ + ++E
Sbjct: 924 DQELRRLEEEACRAAQE 940
Score = 53.5 bits (127), Expect = 2e-06
Identities = 70/233 (30%), Positives = 113/233 (48%), Gaps = 31/233 (13%)
Query: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ-E 1439
++Q+ RA L L R ++ A ++QL + A R R+L A+ + E +++Q E
Sbjct: 771 IIQKNYRAFL-LRRRFLHLKKAAIVFQKQLRGQIA--RRVYRQL-LAEKREQEEKKKQEE 826
Query: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499
EE E E R R REAE Q+ E R QQEL +A +++ +
Sbjct: 827 EEKKKREEEERERERERREAELRAQQEEE------------TRKQQEL-EALQKSQKEAE 873
Query: 1500 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA-LEEEQEAR- 1557
L LEK++ ++ +LR +E E + R +E + LSLT A L++ QE R
Sbjct: 874 LTRELEKQKEN------KQVEEILRLEKEIEDLQ---RMKEQQELSLTEASLQKLQERRD 924
Query: 1558 EELER-QNRALRAELEALLS-SKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
+EL R + A RA E L S + D++ + V +ER+ V + +++L E
Sbjct: 925 QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACE 977
Score = 47.0 bits (110), Expect = 2e-04
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 12/148 (8%)
Query: 1025 QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1084
++L EK E K K+ EE+ E++ + +ER R AE +Q EE K + L
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERER-----REAELRAQQEEETRKQQELE 863
Query: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1144
L+ + A++ L K+++ +Q E L RL+ E +LQ +++QQ A L
Sbjct: 864 ALQKSQKE--AELTRELEKQKENKQVEEIL--RLEKEIEDLQR--MKEQQELSLTEASLQ 917
Query: 1145 RKEEELQAALARAEDEGGARAQ-LLKSL 1171
+ +E L R E+E AQ L+SL
Sbjct: 918 KLQERRDQELRRLEEEACRAAQEFLESL 945
Score = 45.8 bits (107), Expect = 4e-04
Identities = 36/141 (25%), Positives = 74/141 (52%), Gaps = 12/141 (8%)
Query: 1137 EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAE 1196
++LR Q+ R+ A R ++E + + K RE + E +E E+E A+ + E
Sbjct: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE-RERREAELRAQQEEE 855
Query: 1197 KQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE--------EETRIH 1248
+++ +ELEAL+ ++ + +++ +K+ +E+ L+K +E +E +
Sbjct: 856 TRKQ---QELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLT 912
Query: 1249 EAAVQELRQRHGQALGELAEQ 1269
EA++Q+L++R Q L L E+
Sbjct: 913 EASLQKLQERRDQELRRLEEE 933
Score = 43.9 bits (102), Expect = 0.002
Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 20/156 (12%)
Query: 1805 EEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDA 1864
++Q ++ YR+LL + + E K E ++ ER+ +E R +E+
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEE- 854
Query: 1865 GARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE----R 1920
E++ Q E L++ +E L+ +L ++ E + E +L++E+E +
Sbjct: 855 -------------ETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ 901
Query: 1921 RVADQLRDQLEKGNLRVKQLKR--QLEEAEEEASRA 1954
R+ +Q L + +L+ Q +R +L EEEA RA
Sbjct: 902 RMKEQQELSLTEASLQKLQERRDQELRRLEEEACRA 937
Score = 43.9 bits (102), Expect = 0.002
Identities = 41/177 (23%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Query: 1087 RLKYEATIADMEDRLRK-----EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1141
R Y +A+ ++ K EEK ++E E+ +R + +EL+ Q E+ ++ +EL A
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA 864
Query: 1142 -QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
Q +KE EL L + ++ + ++ + + + + Q E + ++ T+A Q+
Sbjct: 865 LQKSQKEAELTRELEKQKEN-----KQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL 919
Query: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257
+ E R E E AQ+ L S E+ E + +E + EL +
Sbjct: 920 QERRDQELRRLEEE---ACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973
Score = 43.9 bits (102), Expect = 0.002
Identities = 54/182 (29%), Positives = 90/182 (49%), Gaps = 38/182 (20%)
Query: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG---RKEEELQAA 1153
+ ++ +EEK +QE E+ K+R E +E+ E+++R ELRAQ RK++EL+A
Sbjct: 812 LAEKREQEEKKKQEEEEKKKR------EEEERERERERREAELRAQQEEETRKQQELEA- 864
Query: 1154 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEAL-RGE 1212
L KS +EA E +LE ++ + E R L +E+E L R +
Sbjct: 865 -------------LQKSQKEA-----ELTRELEKQKENKQVEEILR--LEKEIEDLQRMK 904
Query: 1213 LEDTLDSTNAQ-QELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE 1271
+ L T A Q+L+ +R+QE+ + LEEE AA + L + + E +E
Sbjct: 905 EQQELSLTEASLQKLQERRDQEL----RRLEEEA--CRAAQEFLESLNFDEIDECVRNIE 958
Query: 1272 QA 1273
++
Sbjct: 959 RS 960
Score = 42.0 bits (97), Expect = 0.006
Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%)
Query: 1593 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ- 1651
++A + L A+ E E++ E+ K + E + + + R+ + R + EE R+Q
Sbjct: 802 QIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQ 860
Query: 1652 ----LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1707
L K ++AE+ R+ E+++ V +LE E+E+L+ EA L+K
Sbjct: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA--SLQK 918
Query: 1708 MQAQMKELWREVEE--TRTSREEIFSQN 1733
+Q + + R +EE R ++E + S N
Sbjct: 919 LQERRDQELRRLEEEACRAAQEFLESLN 946
Score = 41.2 bits (95), Expect = 0.010
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 19/139 (13%)
Query: 1178 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1237
LAE +E + E+ + + EK++R+ EE E R E L AQQE ++++QE+ L
Sbjct: 812 LAEKRE--QEEKKKQEEEEKKKRE-EEERERERERREAEL---RAQQEEETRKQQELEAL 865
Query: 1238 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1297
+K+ +E E Q+ ++ + L L +++E +R K E EL
Sbjct: 866 QKSQKEAELTRELEKQKENKQVEEIL-RLEKEIEDLQRMK------------EQQELSLT 912
Query: 1298 LSSLQTARQEGEQRRRRLE 1316
+SLQ ++ +Q RRLE
Sbjct: 913 EASLQKLQERRDQELRRLE 931
Score = 40.4 bits (93), Expect = 0.018
Identities = 64/262 (24%), Positives = 113/262 (43%), Gaps = 26/262 (9%)
Query: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660
D+R + T L +L A +++ +L T L+ E+ L+ R E + +
Sbjct: 698 DVRGKCTSLL-QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756
Query: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720
+ R + RK V +K L L+ + + KQLR A
Sbjct: 757 LARKQYRKVLYCVVIIQKNYRAFL--LRRRFLHLKKAAIVFQKQLRGQIA---------- 804
Query: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780
R ++ ++ RE E++ K E E + +EE +R RR+A+ R + +E
Sbjct: 805 --RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAEL-RAQQEEETRKQQE 861
Query: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840
+A +K Q E +L ELE+++ N ++ + +L ++E L + ++ S
Sbjct: 862 LEAL---QKSQKE---AELTRELEKQKENKQV--EEILRLEKEIEDL-QRMKEQQELSLT 912
Query: 1841 AESGRQQLERQIQELRGRLGEE 1862
S ++ ER+ QELR RL EE
Sbjct: 913 EASLQKLQERRDQELR-RLEEE 933
Score = 38.9 bits (89), Expect = 0.052
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 11/138 (7%)
Query: 1059 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY-EATIADMEDRLRKEEKGRQELEKL-KR 1116
R+LL ++ + + EEEEK K + R + E A++ + +E + +QELE L K
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS 868
Query: 1117 RLDGESSELQEQMVEQQQRAEELR-------AQLGRKEEELQAALARAEDEGGARAQLLK 1169
+ + E + E+ E +Q E LR Q ++++EL A + R Q L+
Sbjct: 869 QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELR 928
Query: 1170 SLREAQAALAEAQEDLES 1187
L E A AQE LES
Sbjct: 929 RLEE--EACRAAQEFLES 944
Score = 38.1 bits (87), Expect = 0.088
Identities = 33/128 (25%), Positives = 66/128 (51%), Gaps = 12/128 (9%)
Query: 1853 QELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEV 1912
++LRG++ AR ++ +A E + + +++ E+E +++ + R E+R E+
Sbjct: 797 KQLRGQI------ARRVYRQLLA--EKREQEEKKKQEEEEKKKREEEERERERERREAEL 848
Query: 1913 VLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESA 1972
Q EEE R +L + L+K + +L R+LE+ +E + RL++E+ED+
Sbjct: 849 RAQQEEETRKQQEL-EALQKSQ-KEAELTRELEKQKENKQVEEI--LRLEKEIEDLQRMK 904
Query: 1973 ESMNREVT 1980
E +T
Sbjct: 905 EQQELSLT 912
Score = 37.7 bits (86), Expect = 0.12
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
Query: 1247 IHEAAVQELRQRHGQALGE-----LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL 1301
+ +AA+ +Q GQ LAE+ EQ + K E+ + E E R +
Sbjct: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
Query: 1302 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1361
A+QE E R+++ +L+ +Q + E R +K + E+ + + + +
Sbjct: 848 LRAQQEEETRKQQ---ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--R 902
Query: 1362 IRLSKELSSTEAQLHDAQELLQEETR 1387
++ +ELS TEA L QE +E R
Sbjct: 903 MKEQQELSLTEASLQKLQERRDQELR 928
Score = 37.0 bits (84), Expect = 0.20
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 30/157 (19%)
Query: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1431
E + + ++ +EE + K R R E A LR Q EEE
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET----------------- 856
Query: 1432 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1491
R+Q+E LEA +++++ A E Q+ ++ E + RLE+ LQ+ +
Sbjct: 857 ----RKQQE----LEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE 908
Query: 1492 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
+ L + ++L+K Q + DQ L + RA +E
Sbjct: 909 LSLTE-----ASLQKLQERRDQELRRLEEEACRAAQE 940
Score = 33.5 bits (75), Expect = 2.2
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 1901 LVRRAEKRLKE--VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1958
L+RR LK+ +V Q + ++A ++ QL ++ K+Q EE +++ + R
Sbjct: 780 LLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER 839
Query: 1959 RRLQRELEDVTESAESMNR--EVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
R +RE E + E + E+ L+ + LT ++ ++EE + ++E E+
Sbjct: 840 ERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIED 899
Query: 2017 AQ 2018
Q
Sbjct: 900 LQ 901
Score = 32.7 bits (73), Expect = 3.7
Identities = 24/125 (19%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Query: 1894 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1953
++ L G++ RR ++L + EE+++ Q ++ +K ++ +R+ EAE A +
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKK---QEEEEKKKREEEERERERERREAELRAQQ 852
Query: 1954 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 2013
+ R++ + E ++ + RE+ + + V ++ RLE+ + +
Sbjct: 853 EEETRKQQELEALQKSQKEAELTRELEKQKE----------NKQVEEILRLEKEIEDLQR 902
Query: 2014 AEEAQ 2018
+E Q
Sbjct: 903 MKEQQ 907
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 449 bits (1156), Expect = e-125
Identities = 310/984 (31%), Positives = 496/984 (50%), Gaps = 114/984 (11%)
Query: 99 MNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAI 158
M+P +DM L LNEA ++HNL RY IYTY+G V +NP++ LP+YT
Sbjct: 59 MHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQ 118
Query: 159 VEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHV 218
V++Y + E+PPHV+A+ Y SM +++ DQ + +GESGAGKTE TK ++Q+LA +
Sbjct: 119 VQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATI 178
Query: 219 ASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 278
+ + +E+Q+L+ANPILEAFGNAKT++NDNSSRFGK+I I F
Sbjct: 179 SGQ-----------------HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYF 221
Query: 279 DVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFL 338
+ +G I GA IE +LLEKSR RQA +E ++HIFY +L G + K L L S Y +L
Sbjct: 222 NPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYL 281
Query: 339 TNGPSSSPG--QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRE--RNT 394
T G +S + + + ++++L FS E ++++++A+L GN+ N
Sbjct: 282 TMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENL 341
Query: 395 DQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKA 454
D + + + A + +LL + + L+ I + ++V ++ QA +A K
Sbjct: 342 DASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKG 401
Query: 455 TYERLFRWLVLRLNRALDRSPRQGAS----FLGILDIAGFEIFQLNSFEQLCINYTNEKL 510
Y LF W+V ++N A+ P Q +G+LDI GFE F+ NSFEQLCIN+ NE L
Sbjct: 402 IYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHL 461
Query: 511 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK 570
QQ F +F +EQEEY+ E I W ++ + D +P +DL+ P +++LLDEE FP+
Sbjct: 462 QQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTLDLL--ALKPMSIISLLDEESRFPQ 518
Query: 571 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV 630
TD + ++K+ + F +P+++ D A F + H+AG+V Y+A +L KN D L+ ++
Sbjct: 519 GTDLTMLQKLNSVHANNKAFLQPKNIHD-ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDI 577
Query: 631 AALLHQSTDRLTAEIWKDE-------HGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVE 683
L++ S ++ EI+ E HG +Q + G+ S +R S
Sbjct: 578 LTLVYSSKNKFLREIFNLELAETKLGHGTIRQ-AKAGNHLFKSADSNKRPS--------- 627
Query: 684 GIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEK 743
T+G +K+SL +LM L+N P F+RCI PN K
Sbjct: 628 --------------------------TLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYK 661
Query: 744 RAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQ 803
+ + L L QLR +G++E + I + GFP R F+EF QR+ +L PNA+ +
Sbjct: 662 KPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLR 721
Query: 804 ACEKMIQALELDPNL-YRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARR 862
I + L + ++ G++KIF R LE +R + +S Q RGY R+
Sbjct: 722 QMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRK 781
Query: 863 AFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRL-FTKVKPLLQ---VTRQDEVLQARAQE 918
F ++++ L+ R Y R+++ + F +++ + + + RQ + ++ R +
Sbjct: 782 EFLRQRRAAVTLQAWWR---GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQ 838
Query: 919 LQK------VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLA 972
LQ V++ Q R V +Q + R + A + AE ++++G L
Sbjct: 839 LQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALP 898
Query: 973 ARKQE-----------LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 1021
A+K+ +E V L A +G +E + H E E
Sbjct: 899 AKKRRSIYDTVTDTEMVEKVFGFLPAMIGGQE-----------------GQASPHFEDLE 941
Query: 1022 GARQKLQLEKVTTEAKMKKFEEDL 1045
QKL + T ++ EED+
Sbjct: 942 SKTQKLLEVDLDTVPMAEEPEEDV 965
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 449 bits (1154), Expect = e-125
Identities = 302/868 (34%), Positives = 448/868 (51%), Gaps = 90/868 (10%)
Query: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
EDM +L L E +VL NL+ R+ LIYTY G V +NPY+ IY V+ Y G+
Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
E PPH++AV A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343
Query: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
+ ++L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA
Sbjct: 1344 ---------------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGA 1387
Query: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--S 345
YLLEKSR + QAK+E ++HIFY+LL G QL+ L+ Y +L G + +
Sbjct: 1388 ITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIA 1447
Query: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQ--ATMPDNT 403
+ + F+ L ++ VLGFS E+ S+ R+++++L GN+ ++ Q A++
Sbjct: 1448 GKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAR 1507
Query: 404 AAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWL 463
Q + LL + +A+ + R+ + T E A A +A+AK Y LF WL
Sbjct: 1508 EIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWL 1567
Query: 464 VLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
+ R+N + SPRQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQ
Sbjct: 1568 ITRVNALV--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQ 1625
Query: 524 EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE 583
EEY RE I W + F D QPCI+LI P G+L +LD++C FP+ATD +F++K
Sbjct: 1626 EEYIREQIDWQEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYH 1682
Query: 584 QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
G +P + +P+ +F++ HYAGKV Y+ +++L KN D + +V L +S R+ A
Sbjct: 1683 HGANPLYSKPK--MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740
Query: 644 EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
+ F P + P + SS
Sbjct: 1741 HL------------FSSHAPQAAPQRLGKSSSV--------------------------T 1762
Query: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
R TV +++SL L+ + NP F+RC+ PNH+K G EP +V+ QLR +GVL
Sbjct: 1763 RLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVL 1822
Query: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQAL-ELDPNLYRVG 822
E +RI ++GFP R+ FQ F RY L A+ C ++ L ++ PN+YRVG
Sbjct: 1823 ETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKHDLPANGDMCVSVLSRLCKVMPNMYRVG 1880
Query: 823 QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
SK+F + + LE R+ + ++ Q RG+ +R F+ + + + ++Q
Sbjct: 1881 VSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHK---IILLQSRAR 1937
Query: 883 AYL-KLRHWQWWRLFTKVKPLLQV---------TRQDEVLQARAQELQKVQELQQQSARE 932
YL + R+ Q R K + L+ R + Q L + +EL ++
Sbjct: 1938 GYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVEGALLWEQEELSKREVVA 1997
Query: 933 VGELQGRVAQLEEERARLAEQLRAEAEL 960
VG L E A LA L+A A L
Sbjct: 1998 VGHL--------EVPAELAGLLQAVAGL 2017
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 441 bits (1135), Expect = e-123
Identities = 290/790 (36%), Positives = 417/790 (52%), Gaps = 82/790 (10%)
Query: 109 DMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRH 168
DM L LNE + ++NL++R+ IYTY G + +NPY+ LPIY+ VE YR + +
Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78
Query: 169 EVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEP 228
E+ PH++A+++ AYRS+ +DQ IL TGESGAGKTE +K V+ Y+A V
Sbjct: 79 ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC--------- 129
Query: 229 GVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGAN 288
G A V+ V + QLLQ+NP+LEAFGNAKTV+NDNSSRFGK++ I FD G +G
Sbjct: 130 GKGAEVNQV-----KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGV 184
Query: 289 IETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE-PCSHYRFLTNGPSSSPG 347
I YLLEKSR ++Q + E +FH+FYQLL GA E+L L LE S Y +L+ + G
Sbjct: 185 ISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNG 244
Query: 348 -QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNT---DQATMPDNT 403
+ F+ +++++GF E S+L +V+AVL+ GNI K E D++ + D
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304
Query: 404 AAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWL 463
+++C L G+ + RA ++ ++ V QA +A +ALAK Y RLF WL
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364
Query: 464 VLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
V R+N ++ + +G+LDI GFEIF+ NSFEQ INY NEKLQQ+F EQ
Sbjct: 365 VNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQ 424
Query: 524 EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFP-KATDKSFVEKVAQ 582
EEY RE I WT +D+ + C DLIE N G+LA+LDEEC P TD++F+EK+ Q
Sbjct: 425 EEYIREDIEWTHIDYFNNAIIC-DLIENNTN--GILAMLDEECLRPGTVTDETFLEKLNQ 481
Query: 583 EQGGHPKFQR-----PRHLRD----QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAAL 633
H F+ R L D + F + HYAGKV Y+ ++ KN D L
Sbjct: 482 VCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNND--------L 533
Query: 634 LHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSS 693
L++ L+ +WK H ++ P G + L++
Sbjct: 534 LYRD---LSQAMWKASHA---------------------LIKSLFPEGNPAKINLKR--- 566
Query: 694 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 753
PP T G +K S++ LM L NP+++RCI PN +K A LV
Sbjct: 567 ----PP----------TAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALV 612
Query: 754 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 813
Q+R G+LE +R+ R G+ R ++ +RY++L P + E + LE
Sbjct: 613 CHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE 672
Query: 814 LDPNLYRVGQSKIFFR-AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQS 872
+ Y G+SKIF R L +LE+ R ++ D+ Q RG+ R F ++ Q
Sbjct: 673 IPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQI 732
Query: 873 ALRVMQRNCA 882
+ R A
Sbjct: 733 VIAAWYRRYA 742
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,145,202
Number of Sequences: 37866
Number of extensions: 3667588
Number of successful extensions: 78983
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 774
Number of HSP's successfully gapped in prelim test: 1672
Number of HSP's that attempted gapping in prelim test: 19707
Number of HSP's gapped (non-prelim): 18964
length of query: 2036
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1918
effective length of database: 13,779,330
effective search space: 26428754940
effective search space used: 26428754940
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.