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Search of human proteins with 115527082
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115527082 myosin, heavy chain 1, skeletal muscle, adult
[Homo sapiens]
(1939 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3752 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3588 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3588 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3577 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3503 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3220 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 3159 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 3150 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 3122 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2600 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2308 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1421 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1421 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1420 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1420 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1405 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1400 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1301 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1301 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1288 0.0
gi|153945715 myosin VC [Homo sapiens] 595 e-169
gi|215982791 myosin VA isoform 1 [Homo sapiens] 586 e-167
gi|215982794 myosin VA isoform 2 [Homo sapiens] 584 e-166
gi|122937345 myosin VB [Homo sapiens] 570 e-162
gi|42794779 myosin 18A isoform b [Homo sapiens] 511 e-144
gi|28416946 myosin 18A isoform a [Homo sapiens] 510 e-144
gi|154354979 myosin X [Homo sapiens] 481 e-135
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 478 e-134
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 478 e-134
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 478 e-134
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 3752 bits (9731), Expect = 0.0
Identities = 1939/1939 (100%), Positives = 1939/1939 (100%)
Query: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV
Sbjct: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
Query: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
Query: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM
Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN
Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLN 660
KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLN 660
Query: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA
Sbjct: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
Query: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEM 780
DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEM
Sbjct: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEM 780
Query: 781 RDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKI 840
RDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKI
Sbjct: 781 RDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKI 840
Query: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
Query: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
Query: 1021 VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQL 1080
VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQL
Sbjct: 1021 VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQL 1080
Query: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR
Sbjct: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1200
SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1200
Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQL 1260
ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQL
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQL 1260
Query: 1261 SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK
Sbjct: 1261 SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
Query: 1321 RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE 1380
RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE
Sbjct: 1321 RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE 1380
Query: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN 1440
TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN 1440
Query: 1441 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLE 1500
AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLE
Sbjct: 1441 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLE 1500
Query: 1501 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG 1560
TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG
Sbjct: 1501 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG 1560
Query: 1561 KILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1620
KILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK
Sbjct: 1561 KILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1620
Query: 1621 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER 1680
KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER
Sbjct: 1621 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER 1680
Query: 1681 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ
Sbjct: 1681 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 1741 IQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800
IQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR
Sbjct: 1741 IQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800
Query: 1801 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE 1860
LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE
Sbjct: 1801 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE 1860
Query: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQ 1920
DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQ
Sbjct: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQ 1920
Query: 1921 VNKLRVKSREVHTKIISEE 1939
VNKLRVKSREVHTKIISEE
Sbjct: 1921 VNKLRVKSREVHTKIISEE 1939
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3588 bits (9305), Expect = 0.0
Identities = 1839/1941 (94%), Positives = 1897/1941 (97%), Gaps = 2/1941 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
MSSDSE+A+FGEAAPFLRKSERERIEAQN+PFDAKTSVFV +PKESFVK T+QSREGGKV
Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
Query: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
T KTE GAT+TVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY EVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEE+TSGK+QGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKP+L
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
Query: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
IEMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAI+ILGFT++E+VSIYKLTGAVM
Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
HYGN+KFKQKQREEQAEPDGTEVADKAAYLQ+LNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
+QV NAVGALAKAVY+KMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHF+LIHYAG VDYNI GWL+KN
Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGG--KKGGKKKGSSFQTVSALFREN 658
KDPLNETVVGLYQKSAMKTLA LF GA AE E GG KKGGKKKGSSFQTVSALFREN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
Query: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718
LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
Query: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLE 778
YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SIDIDHTQYKFGHTKVFFKAGLLGLLE
Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
Query: 779 EMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYF 838
EMRD+KLAQLITRTQA CRGFLARVEYQ+MVERRE+IFCIQYN+R+FMNVKHWPWMKL+F
Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
Query: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 899 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018
DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ 1078
DKVNTLTKAKIKLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKLAQES MDIEN+KQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 1079 QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
QLDEKLKKKEFE+S LQSKIEDEQALG+QLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198
QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 1199 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258
KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN+ETVSKAKGNLEKMCR LED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 1259 QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318
QLSE+K+KEEEQQRLINDLTAQR RLQTESGE+SRQLDEK+ LVSQLSRGKQAFTQQIEE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378
LKRQLEEEIKAK+ALAHALQSSRHDCDLLREQYEEEQE+KAELQRA+SKAN+EVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 1438
YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLM+DVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE+RSL TELFKIKNAYEESLDQ
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE 1558
LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK ELQAALEEAEASLEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 1559 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRL 1618
EGKILRIQLELNQVKSEVDRKIAEKDEEIDQ+KRNHIRIVESMQSTLDAEIRSRNDAIRL
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
Query: 1619 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMV 1678
KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ ILKDTQ+HLDDALRSQEDLKEQLAMV
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
Query: 1679 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
Query: 1739 SQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798
SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
Query: 1799 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQT 1858
RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN EAVKGLRKHER+VKELTYQT
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
Query: 1859 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAE 1918
EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFR++QHELEEAEERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
Query: 1919 SQVNKLRVKSREVHTKIISEE 1939
SQVNKLRVKSREVHTK+ISEE
Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3588 bits (9305), Expect = 0.0
Identities = 1839/1941 (94%), Positives = 1897/1941 (97%), Gaps = 2/1941 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
MSSDSE+A+FGEAAPFLRKSERERIEAQN+PFDAKTSVFV +PKESFVK T+QSREGGKV
Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
Query: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
T KTE GAT+TVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY EVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEE+TSGK+QGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKP+L
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
Query: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
IEMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAI+ILGFT++E+VSIYKLTGAVM
Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
HYGN+KFKQKQREEQAEPDGTEVADKAAYLQ+LNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
+QV NAVGALAKAVY+KMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHF+LIHYAG VDYNI GWL+KN
Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGG--KKGGKKKGSSFQTVSALFREN 658
KDPLNETVVGLYQKSAMKTLA LF GA AE E GG KKGGKKKGSSFQTVSALFREN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
Query: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718
LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
Query: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLE 778
YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SIDIDHTQYKFGHTKVFFKAGLLGLLE
Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
Query: 779 EMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYF 838
EMRD+KLAQLITRTQA CRGFLARVEYQ+MVERRE+IFCIQYN+R+FMNVKHWPWMKL+F
Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
Query: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 899 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018
DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ 1078
DKVNTLTKAKIKLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKLAQES MDIEN+KQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 1079 QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
QLDEKLKKKEFE+S LQSKIEDEQALG+QLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198
QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 1199 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258
KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN+ETVSKAKGNLEKMCR LED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 1259 QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318
QLSE+K+KEEEQQRLINDLTAQR RLQTESGE+SRQLDEK+ LVSQLSRGKQAFTQQIEE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378
LKRQLEEEIKAK+ALAHALQSSRHDCDLLREQYEEEQE+KAELQRA+SKAN+EVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 1438
YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLM+DVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE+RSL TELFKIKNAYEESLDQ
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE 1558
LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK ELQAALEEAEASLEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 1559 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRL 1618
EGKILRIQLELNQVKSEVDRKIAEKDEEIDQ+KRNHIRIVESMQSTLDAEIRSRNDAIRL
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
Query: 1619 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMV 1678
KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ ILKDTQ+HLDDALRSQEDLKEQLAMV
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
Query: 1679 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
Query: 1739 SQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798
SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
Query: 1799 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQT 1858
RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN EAVKGLRKHER+VKELTYQT
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
Query: 1859 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAE 1918
EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFR++QHELEEAEERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
Query: 1919 SQVNKLRVKSREVHTKIISEE 1939
SQVNKLRVKSREVHTK+ISEE
Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 3577 bits (9276), Expect = 0.0
Identities = 1824/1939 (94%), Positives = 1892/1939 (97%)
Query: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
MSSDSEMAIFGEAAPFLRKSE+ERIEAQNKPFDAKTSVFVVDPKES+VKA VQSREGGKV
Sbjct: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
Query: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
TAKTEAGATVTVK+DQVF MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYN EVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEE SGKMQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI+SNKKP+L
Sbjct: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
Query: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
IEMLLITTNPYD+AFVSQGEITVPSIDDQEELMATDSA++ILGFT+DE+V+IYKLTGAVM
Sbjct: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADKAAYL +LNSADLLK+LCYPRVKVGNE+VTKGQTV
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
Query: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QQVYNAVGALAKA+Y+KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSL+HYAGTVDYNIAGWLDKN
Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLN 660
KDPLNETVVGLYQKSAMKTLA LF GA AEAE GGGKKGGKKKGSSFQTVSALFRENLN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN 660
Query: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA
Sbjct: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
Query: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEM 780
DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSI+IDHTQYKFGHTKVFFKAGLLG LEEM
Sbjct: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM 780
Query: 781 RDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKI 840
RDEKLAQLITRTQA+CRGFL RVE++KM+ERRESIFCIQYN+RAFMNVKHWPWMKLYFKI
Sbjct: 781 RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI 840
Query: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
+LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
Sbjct: 901 ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
Query: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ EEDK
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
Query: 1021 VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQL 1080
VNTLTKAK KLEQQVDDLEGSLEQEKK+ MDLERAKRKLEGDLKLAQESTMD ENDKQQL
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL 1080
Query: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+EKLKKKEFEMS LQ KIEDEQAL +QLQKKIKELQARIEELEEEIEAERASRAKAEKQR
Sbjct: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1200
SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRKKH
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQL 1260
ADSVAELGEQID+LQRVKQKLEKEKSE+KMEI+DLASNMETVSKAK N EKMCR LEDQL
Sbjct: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
Query: 1261 SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
SEIKTKEEEQQRLIN+L+AQ+ARL TESGE+SRQLDEKD +VSQLSRGKQAFTQQIEELK
Sbjct: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
Query: 1321 RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE 1380
RQLEEE KAKS LAHALQS+RHDCDLLREQYEEEQEAKAELQR MSKANSEVAQWRTKYE
Sbjct: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
Query: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN 1440
TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN+KCASLEKTKQRLQNEVEDLMIDVER+N
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN 1440
Query: 1441 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLE 1500
AAC ALDKKQRNFDK+LAEWKQK EET AELEASQKESRSLSTELFK+KNAYEESLD LE
Sbjct: 1441 AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE 1500
Query: 1501 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG 1560
TLKRENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EKSELQ +LEEAEASLEHEEG
Sbjct: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG 1560
Query: 1561 KILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1620
KILRIQLELNQVKSE+DRKIAEKDEE+DQ+KRNH+R+VESMQSTLDAEIRSRNDA+R+KK
Sbjct: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 1621 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER 1680
KMEGDLNEMEIQLNHANR AAEALRN RNTQ ILKDTQLHLDDA+R Q+DLKEQLAMVER
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 1681 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
RANL+QAE+EELRA+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLETDISQ
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 1741 IQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800
IQGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ R
Sbjct: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
Query: 1801 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE 1860
LDEAEQLALKGGKKQIQKLEARVRELE EVESEQK NVEAVKGLRKHER+VKELTYQTEE
Sbjct: 1801 LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE 1860
Query: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQ 1920
DRKNILRLQDLVDKLQ KVK+YKRQAEEAEEQSNVNL+KFR++QHELEEA+ERADIAESQ
Sbjct: 1861 DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ 1920
Query: 1921 VNKLRVKSREVHTKIISEE 1939
VNKLRVKSREVHTK+ISEE
Sbjct: 1921 VNKLRVKSREVHTKVISEE 1939
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 3503 bits (9084), Expect = 0.0
Identities = 1786/1937 (92%), Positives = 1874/1937 (96%), Gaps = 3/1937 (0%)
Query: 2 SSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVT 61
SSD+EMA+FGEAAP+LRKSE+ERIEAQNKPFDAKTSVFV +PKES+VK+T+QS+EGGKVT
Sbjct: 4 SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
Query: 62 AKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121
KTE GAT+TV++DQVFPMNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 64 VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
Query: 122 FCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181
FCVTVNPYKWLPVY EVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 124 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
Query: 182 GAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
GAGKTVNTKRVIQYFATIAVTGEKKK+E SGKMQGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 184 GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
Query: 242 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLI 301
DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI SNKKPDLI
Sbjct: 242 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301
Query: 302 EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMH 361
EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAI+ILGFT +E+VSIYKLTGAVMH
Sbjct: 302 EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361
Query: 362 YGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
YGNMKFKQKQREEQAEPDGTEVADKAAYLQ+LNSADLLKALCYPRVKVGNEYVTKGQTVQ
Sbjct: 362 YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
Query: 422 QVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
QVYNAVGALAKAVY+KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422 QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
Query: 482 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 541
NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541
Query: 542 MFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNK 601
MFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHFSLIHYAGTVDYNI GWLDKNK
Sbjct: 542 MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
Query: 602 DPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNK 661
DPLN+TVVGLYQKSAMKTLA LF AEA++ KKG KKKGSSFQTVSALFRENLNK
Sbjct: 602 DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSA-KKGAKKKGSSFQTVSALFRENLNK 660
Query: 662 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 721
LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY D
Sbjct: 661 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720
Query: 722 FKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 781
FKQRYKVLNASAIPEGQFIDSKKASEKLL SIDIDHTQYKFGHTKVFFKAGLLGLLEEMR
Sbjct: 721 FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780
Query: 782 DEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIK 841
DEKLAQ+ITRTQA+CRGFL RVEYQKM++RRE++FCIQYNVRAFMNVKHWPWMKL+FKIK
Sbjct: 781 DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840
Query: 842 PLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADS 901
PLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQ+EADS
Sbjct: 841 PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
Query: 902 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDIDDL
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1021
ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQAEEDKV
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 1022 NTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLD 1081
N LTKAK KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKLAQESTMD+ENDKQQLD
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 1082 EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
EKL+KKEFE+S L SKIEDEQA+ +QLQKKIKELQARIEEL EEIEAERASRAKAEKQRS
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201
DLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA A LRKKHA
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
Query: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261
DS+AELGEQIDNLQRVKQKLEKEKSE+KME DDL+SN E +SKAKGNLEKMCR+LEDQ+S
Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260
Query: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKR 1321
E+KTKEEEQQRLINDLTAQRARLQTE+GEYSRQLDEKD LVSQLSR KQA TQQIEELK
Sbjct: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
Query: 1322 QLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYET 1381
QLEEE KAK+ALAHALQSSRHDCDLLREQYEEEQE KAELQRA+SKANSEVAQWRTKYET
Sbjct: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
Query: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNA 1441
DAIQRTEELEEAKKKLAQRLQ+AEEHVEAVNAKCASLEKTKQRLQNEVEDLM+DVER+NA
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
Query: 1442 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLET 1501
ACAALDKKQRNFDK+L+EWKQK EET AELEASQKESRSLSTELFK+KN YEESLDQLET
Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
Query: 1502 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGK 1561
L+RENKNLQQEISDLTEQIAEGGK+IHELEKIKKQVEQEK E+QAALEEAEASLEHEEGK
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
Query: 1562 ILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1621
ILRIQLELNQVKSEVDRKIAEKDEEIDQ+KRNH R+VE+MQSTLDAEIRSRNDA+R+KKK
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620
Query: 1622 MEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERR 1681
MEGDLNEMEIQLNHANR+AAE+LRNYRNTQ ILK+TQLHLDDALR QEDLKEQLA+VERR
Sbjct: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
Query: 1682 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQI 1741
ANLLQAEIEEL ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE D+SQ+
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
Query: 1742 QGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801
Q E+E++IQE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL
Sbjct: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
Query: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEED 1861
DEAEQLALKGGKKQIQKLEARVRELEGEVE+EQKRN EAVKGLRKHER+VKELTYQTEED
Sbjct: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860
Query: 1862 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921
RKN+LRLQDLVDKLQAKVKSYKRQAEEAEEQSN NLSKFR++QHELEEAEERADIAESQV
Sbjct: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920
Query: 1922 NKLRVKSREVHTKIISE 1938
NKLRVKSREVHTKI +E
Sbjct: 1921 NKLRVKSREVHTKISAE 1937
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 3220 bits (8348), Expect = 0.0
Identities = 1627/1931 (84%), Positives = 1792/1931 (92%), Gaps = 5/1931 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
MSSD+EM +FG AAPFLRKSE+ERIEAQN+PFDAKT FVVD KE + K ++S + GKV
Sbjct: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
Query: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
T +TE T+ VK + V+ MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYN EVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIA TG+ K++ KM+GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVR 238
Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI+SNKKP+L
Sbjct: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298
Query: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
IE+LLITTNPYDY F+SQGEI V SIDD EEL+ATDSAI+ILGFT +E+ +YKLTGAVM
Sbjct: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADK AYL LNS+DLLKALC+PRVKVGNEYVTKGQTV
Sbjct: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418
Query: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QV++AV AL+K+VY+K+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKSNNFQKPK KG+ EAHFSLIHYAGTVDY+++GWL+KN
Sbjct: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598
Query: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKG-GKKKGSSFQTVSALFRENL 659
KDPLNETVVGLYQKS+ + LA L+ AT A A+A GKK KKKGSSFQTVSALFRENL
Sbjct: 599 KDPLNETVVGLYQKSSNRLLAHLY--ATFATADADSGKKKVAKKKGSSFQTVSALFRENL 656
Query: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719
NKLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 657 NKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILY 716
Query: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEE 779
DFKQRY+VLNASAIPEGQFIDSKKA EKLL SIDIDHTQYKFGHTKVFFKAGLLG LEE
Sbjct: 717 GDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEE 776
Query: 780 MRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFK 839
MRD++LA+LITRTQA+CRGFL RVE+QKMV+RRESIFCIQYN+R+FMNVKHWPWMKL+FK
Sbjct: 777 MRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFK 836
Query: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899
IKPLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEK+VTL+QEKNDLQLQVQAE+
Sbjct: 837 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES 896
Query: 900 DSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
++L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID
Sbjct: 897 ENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 956
Query: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019
DLELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQAEED
Sbjct: 957 DLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEED 1016
Query: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQ 1079
KVN+L K K KLEQQV+DLE SLEQEKK+R+DLER KRKLEGDLKLAQES +D+ENDKQQ
Sbjct: 1017 KVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ 1076
Query: 1080 LDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
LDE+LKKK+FE LQSK+EDEQ LG+Q QKKIKELQARIEELEEEIEAERA+RAK EKQ
Sbjct: 1077 LDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQ 1136
Query: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
RSD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRKK
Sbjct: 1137 RSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKK 1196
Query: 1200 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ 1259
HADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDDL+S+ME+VSK+K NLEK+CR LEDQ
Sbjct: 1197 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQ 1256
Query: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL 1319
LSE + K EE QR +++LT Q++RLQTE+GE SRQL+EK+++VSQLSR KQAFTQQ EEL
Sbjct: 1257 LSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEEL 1316
Query: 1320 KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY 1379
KRQLEEE KAK+ALAHALQSSRHDCDLLREQYEEEQE KAELQRA+SKANSEVAQWRTKY
Sbjct: 1317 KRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1376
Query: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT 1439
ETDAIQRTEELEEAKKKLAQRLQD+EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER
Sbjct: 1377 ETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERA 1436
Query: 1440 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQL 1499
N+ AALDKKQRNFDK+LAEWK KCEE+ AELEAS KESRSLSTELFK+KNAYEE+LDQL
Sbjct: 1437 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 1496
Query: 1500 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEE 1559
ET+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK+++Q ALEEAEA+LEHEE
Sbjct: 1497 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 1556
Query: 1560 GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
KILRIQLEL QVKSE+DRKIAEKDEEI+Q+KRN+ R VE+MQS LDAE+RSRN+AIRLK
Sbjct: 1557 AKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLK 1616
Query: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
KKMEGDLNE+EIQL+HANR AAE L++ R+ Q LKDTQLHLDDALR QEDLKEQLA+VE
Sbjct: 1617 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 1676
Query: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
RRANLLQAE+EELRATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+
Sbjct: 1677 RRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLM 1736
Query: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Q+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH
Sbjct: 1737 QLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1796
Query: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTE 1859
RLDEAEQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ER+VKELTYQ+E
Sbjct: 1797 RLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSE 1856
Query: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAES 1919
EDRKN+LRLQDLVDKLQ KVKSYKRQAEEA+EQ+N +L+KFR+ QHELEEAEERADIAES
Sbjct: 1857 EDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAES 1916
Query: 1920 QVNKLRVKSRE 1930
QVNKLR K+R+
Sbjct: 1917 QVNKLRAKTRD 1927
Score = 228 bits (581), Expect = 4e-59
Identities = 220/964 (22%), Positives = 432/964 (44%), Gaps = 110/964 (11%)
Query: 994 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLE 1053
A+ KE ++E Q+T D+L E K L + + L Q+ +DL+ ++ E + +D E
Sbjct: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
Query: 1054 RAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIK 1113
++ D+ +K K QL+ KIK
Sbjct: 904 ------------------------ERCDQLIKAK------------------FQLEAKIK 921
Query: 1114 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1172
E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++
Sbjct: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970
Query: 1173 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEMK 1229
A K++ EE + E A R+K A A + +D+LQ + K L K KS+++
Sbjct: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029
Query: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG 1289
+++DL S++E K + +LE+ R LE ++K +E L ND RL+ +
Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086
Query: 1290 EYSR---QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1346
EY + +++++ TL Q + + +IEEL+ ++E E ++ + +
Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
L E+ EE + K +E + R E +Q + +KK A + + E
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGE 1206
Query: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
++ + LEK K + E++DL +E + + A L+K R + L+E + K EE
Sbjct: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE 1266
Query: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
L + L TE ++ EE + L R + Q+ +L Q+ E K
Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
Query: 1527 I-----------HELEKIKKQVEQE---KSELQAALEEAEASLEHEEGKILRIQLELNQV 1572
H+ + +++Q E+E K+ELQ AL +A + E+ Q
Sbjct: 1327 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS--------------EVAQW 1372
Query: 1573 KSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1632
+++ + ++ EE+++ K+ + ++ + ++A + K++++G++ ++ +
Sbjct: 1373 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 1432
Query: 1633 LNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE-DLKEQLAMVERRANLLQAEIEE 1691
+ AN +AA + RN +L + + +++ E LKE ++ L A EE
Sbjct: 1433 VERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA-YEE 1491
Query: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQE 1751
LE +R K EQE+ D +E++ L ++K++E + + IQ +E+
Sbjct: 1492 ALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAA 1551
Query: 1752 ARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALK 1810
+ E K + + + E+ +K + +E++K+N ++TV+ +Q LD AE +
Sbjct: 1552 LEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD-AEVRSRN 1610
Query: 1811 GGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQD 1870
+ +K+E + E+E ++ ++ E +K LR + ++K+ T+ + LR Q+
Sbjct: 1611 EAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKD----TQLHLDDALRGQE 1666
Query: 1871 LVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSRE 1930
K Q E ++N+ ++ ++ LE+ E +AE ++ + +
Sbjct: 1667 ----------DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQL 1716
Query: 1931 VHTK 1934
+HT+
Sbjct: 1717 LHTQ 1720
Score = 179 bits (454), Expect = 2e-44
Identities = 195/844 (23%), Positives = 364/844 (43%), Gaps = 113/844 (13%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKR----KELEEKMVTLMQEKNDLQLQVQAEAD 900
K E + + ++EE E + AKTE +R +ELEE L + Q++
Sbjct: 1108 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 1167
Query: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDE-----EEINAELTAKKRKLEDECSELK 955
A+ + L + +Q EA + + ++ D E+I+ L K+KLE E SE K
Sbjct: 1168 REAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQID-NLQRVKQKLEKEKSEFK 1226
Query: 956 KDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-------LDETIAKLTKEKKALQEAHQ 1008
+IDDL ++ V K K E + L ++++ + ++++LT +K LQ
Sbjct: 1227 LEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAG 1286
Query: 1009 QTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQE 1068
+ L+ +E V+ L+++K QQ ++L+ LE+E K + L A + D L +E
Sbjct: 1287 ELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLRE 1346
Query: 1069 STMDIENDKQQLDEKLKKKEFEMSGLQSKIE-DEQALGMQLQKKIKELQARIEELEEEIE 1127
+ + K +L L K E++ ++K E D +L++ K+L R+++ EE++E
Sbjct: 1347 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVE 1406
Query: 1128 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1187
A A A EK + L E+E++ +E A +A + + + + + EE+
Sbjct: 1407 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQA 1466
Query: 1188 QHEATAATLRKKHADSVA---ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSK 1244
+ EA+ R + E +D L+ VK +E ++ EI DL + K
Sbjct: 1467 ELEASLKESRSLSTELFKLKNAYEEALDQLETVK----RENKNLEQEIADLTEQIAENGK 1522
Query: 1245 AKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE----SGEYSRQLDEKDT 1300
LEK + +E + ++I+ EE + + A+ R+Q E E R++ EKD
Sbjct: 1523 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582
Query: 1301 LVSQLSRGKQAFTQQIEE--------------LKRQLEEEI-KAKSALAHALQSSRHDCD 1345
+ QL R Q + ++ LK+++E ++ + + L+HA + +
Sbjct: 1583 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLK 1642
Query: 1346 LLREQYEEEQEAKAELQRAMS-----KANSEVAQWRTKY---ETDAIQRT-EELEEAKKK 1396
LR + ++ + L A+ K + + R E + ++ T E+ E A+K
Sbjct: 1643 HLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKL 1702
Query: 1397 LAQRLQDAEEHVEAVNAKCASLEKTKQRL-------QNEVEDLMIDVER---------TN 1440
Q L D+ E V+ ++ + SL TK++L Q+EVED D T+
Sbjct: 1703 AEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 1762
Query: 1441 AACAA------------LDKKQRNFDKILAEWKQKCEETHA------------------- 1469
AA A L++ ++N ++ + + + + +E
Sbjct: 1763 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1822
Query: 1470 ---ELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
ELE QK+ +TE K YE + +L E++ + DL +++ K
Sbjct: 1823 LEFELEGEQKK----NTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
Query: 1527 I-HELEKIKKQVEQEKSELQAA---LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1582
+ E+ +Q ++ + A LEEAE + E ++ +++ + S R +
Sbjct: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTS--SRMVVH 1936
Query: 1583 KDEE 1586
+ EE
Sbjct: 1937 ESEE 1940
Score = 38.9 bits (89), Expect = 0.049
Identities = 25/130 (19%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 1813 KKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLV 1872
+K++ ++ ++ + E+ + + E + L ++ +L Q + + +N+L ++
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
Query: 1873 DKL-------QAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLR 1925
D+L +AK+K +AE+ EE + +K R+++ E E ++ D E + K+
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
Query: 1926 VKSREVHTKI 1935
+ K+
Sbjct: 967 KEKHATENKV 976
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 3159 bits (8189), Expect = 0.0
Identities = 1588/1939 (81%), Positives = 1766/1939 (91%), Gaps = 2/1939 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
MSSD+EMAIFGEAAP+LRK E+ERIEAQN+PFD+K + FV D KE +VK +Q+RE KV
Sbjct: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60
Query: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
KT +T+ +DQVFPMNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY EVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTG+KKKE GKMQGTLEDQII ANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKE-TQPGKMQGTLEDQIIQANPLLEAFGNAKTVR 239
Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQL +ERSYHIFYQIMSNKKP+L
Sbjct: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299
Query: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
I++LLI+TNP+D+ FVSQGE+TV SIDD EEL+ATD+AI+ILGF+S+E+V IYKLTGAVM
Sbjct: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNEYVTKGQ V
Sbjct: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419
Query: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QQV N+VGALAKAVY+KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKSNNFQKPKPAKGK EAHFSL+HYAGTVDYNIAGWLDKN
Sbjct: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599
Query: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEA-EAGGGKKGGKKKGSSFQTVSALFRENL 659
KDPLNETVVGLYQKS++K L+ LF GAE ++GG KKGGKKKGSSFQTVSA+FRENL
Sbjct: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENL 659
Query: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719
NKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRILY
Sbjct: 660 NKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILY 719
Query: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEE 779
ADFKQRY++LNASAIPEGQFIDSK ASEKLL SID+D Q++FG+TKVFFKAGLLGLLEE
Sbjct: 720 ADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEE 779
Query: 780 MRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFK 839
MRDEKL L+T TQA+CRG+L RVE++KM+ERR+SIFCIQYN+R+FMNVKHWPWM L+FK
Sbjct: 780 MRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFK 839
Query: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899
IKPLLKSAE EKEMA MKE+FE+TKEELA++EA+RKELEEKMV+L+QEKNDLQLQVQ+E
Sbjct: 840 IKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSET 899
Query: 900 DSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
++L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DID
Sbjct: 900 ENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID 959
Query: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019
DLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ EED
Sbjct: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019
Query: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQ 1079
KVN L K KLEQQ DDLEGSLEQEKK+R DLERAKRKLEGDLK++QES MD+ENDKQQ
Sbjct: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079
Query: 1080 LDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
++EKLKKKEFE+S LQ+KI+DEQ +Q QKKIKELQARIEELEEEIEAE RAK EKQ
Sbjct: 1080 IEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139
Query: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
RSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK
Sbjct: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
Query: 1200 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ 1259
ADSVAELGEQIDNLQRVKQKLEKEKSE+KMEIDD+ASN+E +SK+K N+E+ CR +EDQ
Sbjct: 1200 QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259
Query: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL 1319
SEIK K+E+Q +LI+DL Q+ARLQT++GE S +++EK++L+SQL++ KQA TQQ+EEL
Sbjct: 1260 FSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEEL 1319
Query: 1320 KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY 1379
KRQ+EEE KAK+A+AHALQSSRHDCDLLREQYEEEQEAKAELQRA+SKANSEVAQWRTKY
Sbjct: 1320 KRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY 1379
Query: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT 1439
ETDAIQRTEELEEAKKKLAQRLQ+AEE+ E N+KCASLEKTKQRLQ EVEDLM D+ER+
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERS 1439
Query: 1440 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQL 1499
+ ACA LDKKQRNFDK+LAEWKQK +E+ AELEA+QKESRSLSTELFK++NAYEE +DQL
Sbjct: 1440 HTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQL 1499
Query: 1500 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEE 1559
ETL+RENKNLQ+EISDLTEQIAE GK + E EK KK VEQEKS+LQ ALEE E SLEHEE
Sbjct: 1500 ETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEE 1559
Query: 1560 GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
KILR+QLEL+QVKSE+DRK+ EKDEEI+Q+KRN R E++QS LDAEIRSRNDA+RLK
Sbjct: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619
Query: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
KKMEGDLNEMEIQL H+NR AE ++ R Q LKD+QLHLDDALRS EDLKEQLA+VE
Sbjct: 1620 KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE 1679
Query: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
RR LL E+EE++ LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI+
Sbjct: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA 1739
Query: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Q Q E+E+ IQE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH
Sbjct: 1740 QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Query: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTE 1859
RLDEAEQLALKGGKKQIQKLE RVRELE E++ EQKR EA+KG K+ERKVKE+TYQ E
Sbjct: 1800 RLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAE 1859
Query: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAES 1919
ED KNILRLQDLVDKLQAKVKSYKRQAEEAEEQ+N LS+ RR+QHELEEA ERADIAES
Sbjct: 1860 EDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAES 1919
Query: 1920 QVNKLRVKSREVHTKIISE 1938
QVNKLR KSR+V ++ + E
Sbjct: 1920 QVNKLRAKSRDVGSQKMEE 1938
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 3150 bits (8166), Expect = 0.0
Identities = 1573/1936 (81%), Positives = 1767/1936 (91%), Gaps = 3/1936 (0%)
Query: 4 DSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAK 63
DSEMA+FG AAP+LRKSE+ER+EAQ +PFD K VFV D K+ FVKA + SREGGKVTA+
Sbjct: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
Query: 64 TEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
TE G TVTVK+DQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
Query: 124 VTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
VTVNPYKWLPVY EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
Query: 184 GKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
Query: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEM 303
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER YHIFYQI+SNKKP+L++M
Sbjct: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
Query: 304 LLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYG 363
LLIT NPYDYAF+SQGE TV SIDD EELMATD+A ++LGFTS+E+ S+YKLTGA+MH+G
Sbjct: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
Query: 364 NMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 423
NMKFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ VQQV
Sbjct: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
Query: 424 YNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
A GALAKAVY++MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
Query: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
Query: 544 PKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDP 603
PKATD +FK KL++ HLGKS NFQKP+ KGKPEAHFSLIHYAG VDYNI GWL KNKDP
Sbjct: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
Query: 604 LNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLM 663
LNETVVGLYQKS++K L+ LF GA+A GK G KKGSSFQTVSAL RENLNKLM
Sbjct: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGK-GKAKKGSSFQTVSALHRENLNKLM 659
Query: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
TNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF+
Sbjct: 660 TNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 719
Query: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDE 783
QRY++LN +AIPEGQFIDS+K +EKLL S+DIDH QYKFGHTKVFFKAGLLGLLEEMRDE
Sbjct: 720 QRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 779
Query: 784 KLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPL 843
+L+++ITR QA RG LAR+EY+K++ERR+S+ IQ+N+RAFM VK+WPWMKLYFKIKPL
Sbjct: 780 RLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPL 839
Query: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLA 903
LKSAE EKEMA+MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D+LA
Sbjct: 840 LKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLA 899
Query: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDLEL
Sbjct: 900 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLEL 959
Query: 964 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1023
TLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQAEEDKVNT
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEK 1083
LTKAK+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDKQQLDE+
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
Query: 1084 LKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
LKKK+FE++ L ++IEDEQALG QLQKK+KELQARIEELEEE+EAER +RAK EK RSDL
Sbjct: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 1144 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1203
SRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHADS
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 1204 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 1263
VAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SNME + KAK NLEKMCR LEDQ++E
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 1264 KTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQL 1323
++K EE QR +NDLT+QRA+LQTE+GE SRQLDEK+ L+SQL+RGK +TQQ+E+LKRQL
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
EEE+KAK+ALAHALQS+RHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETDA
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAAC 1443
IQRTEELEEAKKKLAQRLQ+AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NAA
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439
Query: 1444 AALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLK 1503
AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKE+RSLSTELFK+KNAYEESL+ LET K
Sbjct: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499
Query: 1504 RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKIL 1563
RENKNLQ+EISDLTEQ+ GK IHELEK++KQ+E EK ELQ+ALEEAEASLEHEEGKIL
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559
Query: 1564 RIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME 1623
R QLE NQ+K+E++RK+AEKDEE++Q KRNH+R+V+S+Q++LDAE RSRN+A+R+KKKME
Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619
Query: 1624 GDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRAN 1683
GDLNEMEIQL+HANRMAAEA + ++ Q++LKDTQ+ LDDA+R+ +DLKE +A+VERR N
Sbjct: 1620 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1679
Query: 1684 LLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743
LLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+Q
Sbjct: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQT 1739
Query: 1744 EMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803
E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDE
Sbjct: 1740 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1799
Query: 1804 AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRK 1863
AEQ+ALKGGKKQ+QKLEARVRELE E+E+EQKRN E+VKG+RK ER++KELTYQTEEDRK
Sbjct: 1800 AEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRK 1859
Query: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNK 1923
N+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFR++QHEL+EAEERADIAESQVNK
Sbjct: 1860 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1919
Query: 1924 LRVKSREVHTKIISEE 1939
LR KSR++ TK ++EE
Sbjct: 1920 LRAKSRDIGTKGLNEE 1935
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 3122 bits (8093), Expect = 0.0
Identities = 1557/1932 (80%), Positives = 1756/1932 (90%), Gaps = 1/1932 (0%)
Query: 3 SDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTA 62
+D++MA FG AA +LRKSE+ER+EAQ +PFD +T FV D KE FVKA + SREGGKV A
Sbjct: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
Query: 63 KTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
+TE G TVTVK+DQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
Query: 123 CVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
CVTVNPYKWLPVYNAEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
Query: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
AGKTVNTKRVIQYFA+IA G++ K++ + +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240
Query: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIE 302
NSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER+YHIFYQI+SNKKP+L++
Sbjct: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
Query: 303 MLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHY 362
MLL+T NPYDYAFVSQGE++V SIDD EELMATDSA ++LGFTS+E+ +YKLTGA+MHY
Sbjct: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
Query: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQ 422
GNMKFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ+VQQ
Sbjct: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
Query: 423 VYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
VY ++GALAKAVY+KMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
Query: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
Query: 543 FPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKD 602
FPKATD +FK KLY+ HLGKSNNFQKP+ KGK EAHFSLIHYAGTVDYNI GWL+KNKD
Sbjct: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
Query: 603 PLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKL 662
PLNETVV LYQKS++K +A LF A+ G KGGKKKGSSFQTVSAL RENLNKL
Sbjct: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
Query: 663 MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 722
MTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF
Sbjct: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
Query: 723 KQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRD 782
+QRY++LN AIPEGQFIDS+K +EKLL S+DIDH QYKFGHTKVFFKAGLLGLLEEMRD
Sbjct: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
Query: 783 EKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKP 842
E+L+++ITR QA RG L R+E++K+VERR+++ IQ+N+RAFM VK+WPWMKLYFKIKP
Sbjct: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
Query: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSL 902
LLKSAETEKEMA MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D+L
Sbjct: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
Query: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDDLE
Sbjct: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
LTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDKVN
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
Query: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDE 1082
+L+K+K+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDK QL+E
Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 1083 KLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
KLKKKEF+++ SKIEDEQ L +QLQKK+KE QARIEELEEE+EAER +RAK EK RSD
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
Query: 1143 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1202
LSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHAD
Sbjct: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
Query: 1203 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSE 1262
SVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SNME + KAK NLEK+ R LEDQ +E
Sbjct: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
Query: 1263 IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQ 1322
+ K EE QR +ND T QRA+LQTE+GE +RQL+EK+ L+SQL+RGK ++TQQ+E+LKRQ
Sbjct: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
Query: 1323 LEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD 1382
LEEE KAK+ALAHALQS+RHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETD
Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
Query: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAA 1442
AIQRTEELEEAKKKLAQRLQDAEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NAA
Sbjct: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
Query: 1443 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETL 1502
AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKE+RSLSTELFK+KNAYEESL+ LET
Sbjct: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
Query: 1503 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKI 1562
KRENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK ELQ+ALEEAEASLEHEEGKI
Sbjct: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
Query: 1563 LRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM 1622
LR QLE NQ+K+E++RK+AEKDEE++Q KRNH R+V+S+Q++LDAE RSRN+ +R+KKKM
Sbjct: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
Query: 1623 EGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRA 1682
EGDLNEMEIQL+HANRMAAEA + ++ Q++LKDTQ+ LDDA+R+ +DLKE +A+VERR
Sbjct: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 1683 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQ 1742
NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q+Q
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
Query: 1743 GEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1802
E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLD
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 1803 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDR 1862
EAEQ+ALKGGKKQ+QKLEARVRELEGE+E+EQKRN E+VKG+RK ER++KELTYQTEED+
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVN 1922
KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFR++QHEL+EAEERADIAESQVN
Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 1923 KLRVKSREVHTK 1934
KLR KSR++ K
Sbjct: 1921 KLRAKSRDIGAK 1932
Score = 188 bits (477), Expect = 5e-47
Identities = 193/848 (22%), Positives = 372/848 (43%), Gaps = 100/848 (11%)
Query: 1106 MQLQKKIKELQARIE-ELEEEIEAERASRAKAEKQRSDLSR-ELEEISERLEEAGGATSA 1163
M+L KIK L E E E E R K ++S+ R ELEE L +
Sbjct: 832 MKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQL 891
Query: 1164 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1223
Q++ + + ++ L + +Q EA + ++ D E L K+KLE
Sbjct: 892 QVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE----EMNAELTAKKRKLED 947
Query: 1224 EKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRAR 1283
E SE+K +IDDL + V K K E + L ++++ + +I LT ++
Sbjct: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DEIIAKLTKEKKA 1000
Query: 1284 LQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHD 1343
LQ + L ++ V+ LS+ K QQ+++L+ LE+E K + L A + D
Sbjct: 1001 LQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1060
Query: 1344 CDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403
L +E + + K +L+ + K ++ Q +K E + + + L++ K+ R+++
Sbjct: 1061 LKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ-LQKKLKENQARIEE 1119
Query: 1404 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAAL----DKKQRNFDKILAE 1459
EE +EA A +EK + L E+E++ +E A + K++ F K+ +
Sbjct: 1120 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1179
Query: 1460 WKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLK----RENKNLQQEISD 1515
++ + A A +K+ EL E +D L+ +K +E + E+ D
Sbjct: 1180 LEEATLQHEATAAALRKKHADSVAEL-------GEQIDNLQRVKQKLEKEKSEFKLELDD 1232
Query: 1516 LTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1575
+T + + K LEK+ + +E + +E + LEEA+ SL + ++Q E E
Sbjct: 1233 VTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE----NGE 1288
Query: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1635
+ R++ EK+ I Q+ R + + M+ LK+++E +
Sbjct: 1289 LARQLEEKEALISQLTRGKLSYTQQMED--------------LKRQLEEE--------GK 1326
Query: 1636 ANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA------EI 1689
A A AL++ R+ +L++ + + K +L V +AN A E
Sbjct: 1327 AKNALAHALQSARHDCDLLREQY-------EEETEAKAELQRVLSKANSEVAQWRTKYET 1379
Query: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749
+ ++ T E E +K+A Q L DA E V+ ++ + +SL TK +L Q E+ED++
Sbjct: 1380 DAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEKTKHRL-------QNEIEDLM 1431
Query: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809
+ + A A L++ ++N ++ + + + + +E+ Q L
Sbjct: 1432 VDVERSNAAA---------------------AALDKKQRNFDKILAEWKQKYEES-QSEL 1469
Query: 1810 KGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKH-ERKVKELTYQTEEDRKNILRL 1868
+ +K+ + L + +L+ E E ++E K K+ + ++ +LT Q E KN+ L
Sbjct: 1470 ESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
Query: 1869 QDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKS 1928
+ + +L+ + + EEAE K R Q E + + + ++ ++ ++
Sbjct: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQA 1588
Query: 1929 REVHTKII 1936
+ H +++
Sbjct: 1589 KRNHQRVV 1596
Score = 66.2 bits (160), Expect = 3e-10
Identities = 64/313 (20%), Positives = 139/313 (44%), Gaps = 44/313 (14%)
Query: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADA 905
+AE +K++ +++ + T+ +L +L+E + +++ +N+L +QAE + L
Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN-IAIVERRNNL---LQAELEELRAV 1693
Query: 906 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 965
E+ ++ K E ++ E +ER + N L +K+K+E + ++L+ ++++
Sbjct: 1694 VEQTERSRKLA---EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750
Query: 966 AKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1025
E++ + EE+ +T A L + KK ++ QT+ DLQ D+ +
Sbjct: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1806
Query: 1026 -----KAKIKLEQQVDDLEGSL----------------------------EQEKKIRMDL 1052
K KLE +V +LEG L E++KK + L
Sbjct: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866
Query: 1053 ERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKI 1112
+ KL+ +K + + E K +K + E+ + + + ++ +L+ K
Sbjct: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926
Query: 1113 KELQARIEELEEE 1125
+++ A+ + +EE
Sbjct: 1927 RDIGAKQKMHDEE 1939
Score = 33.1 bits (74), Expect = 2.7
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 1841 VKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKF 1900
+K L K KE+ EE R+++ ++K +A+ K + + ++ N +
Sbjct: 838 IKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQV 893
Query: 1901 RRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
+ Q L +AEER D +L K +E++ ++ EE
Sbjct: 894 QAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE 932
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 2600 bits (6738), Expect = 0.0
Identities = 1300/1931 (67%), Positives = 1615/1931 (83%), Gaps = 6/1931 (0%)
Query: 6 EMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSRE-GGKVTAKT 64
+++ GE+A +LR+ +E + P+D K V+V D ++++V+A V+S GG+VT +T
Sbjct: 45 DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104
Query: 65 EAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
+ + V++ ++ PMNPP++D +EDMAMMTHL+E +VL+NL++RYA WMIYTYSGLFCV
Sbjct: 105 KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164
Query: 125 TVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
T+NPYKWLPVY A VV AY+GK+R ++PPHI++++DNAY ML +R+NQS+LITGESGAG
Sbjct: 165 TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224
Query: 185 KTVNTKRVIQYFATIAVTGEK--KKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
KTVNTKRVIQYFA +A G+ KK + + K GTLEDQII ANP +EAFGNAKT+RND
Sbjct: 225 KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284
Query: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIE 302
NSSRFGKFIRIHFG +GKLASADI++YLLEKSRV FQL ERSYH++YQI+S +KP+L +
Sbjct: 285 NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344
Query: 303 MLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHY 362
MLL++ NPYDY F SQG ITV +++D EEL+ATD A++ILGF+ DE+ + YK+ GA++H+
Sbjct: 345 MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404
Query: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQ 422
GNMKFKQKQREEQAE DGTE ADKAAYL ++S DLLK L +PRV+VGNEYVTKGQ+V+Q
Sbjct: 405 GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464
Query: 423 VYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
V AVGALAKA YD++F W+V+RINQ LDTK PRQ+FIGVLDIAGFEIF+FNS EQLCIN
Sbjct: 465 VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524
Query: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL CI+LIEKP+GI SILEEECM
Sbjct: 525 FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584
Query: 543 FPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKPEAHFSLIHYAGTVDYNIAGWLDKNK 601
FPKA+D SF+ KLY+ H GKS NFQ+P+P K K +AHF ++HYAG V Y+I GWL+KNK
Sbjct: 585 FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644
Query: 602 DPLNETVVGLYQKSAMKTLALLFVGATGA--EAEAGGGKKGGKKKGSSFQTVSALFRENL 659
DPLNETVV ++QKS + LA L+ G+ G K +KK +SFQTVS L +ENL
Sbjct: 645 DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENL 704
Query: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719
NKLMTNLR+T PHFVRCI+PNE KTPG M+ LVLHQLRCNGVLEGIRICR+GFP+R+LY
Sbjct: 705 NKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLY 764
Query: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEE 779
DF+QRY++LN SAIP+ F+DS+KA+EKLLGS+D+DHTQY+FGHTKVFFKAGLLG+LEE
Sbjct: 765 TDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEE 824
Query: 780 MRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFK 839
+RD++LA+++T QA RG L R+EYQ+++ R+++F IQ+N+RAF VK+W WMKL+FK
Sbjct: 825 LRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFK 884
Query: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899
+KPLL+SA+ E+E+A ++ E + LA EAKR+ELEE V++ QEKNDL LQ+QAE
Sbjct: 885 MKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQ 944
Query: 900 DSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
D+LADAEERC LIK+K+QLE K+KE++ER EDEEE+NA+L A++RKLEDEC+ELKKDID
Sbjct: 945 DNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDID 1004
Query: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019
DL+LTLAK EKEK ATENKVKNLTEEMA LDE++A+LTKEKKALQEAHQQ L DLQAEED
Sbjct: 1005 DLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEED 1064
Query: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQ 1079
+V+ LTKAK++LEQQV+DLE SLEQEKK+RMD ERAKRKLEGDLKL QES D DKQQ
Sbjct: 1065 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1124
Query: 1080 LDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
L+EKLKKK+ E+S L ++EDEQ LG Q+QKKIKELQAR EELEEE+EAERA+RA+ EKQ
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1184
Query: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
R++ +RELEE+SERLEEAGGA++ Q E +KREAE ++RR+LEEA L+HEAT A LR+K
Sbjct: 1185 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRK 1244
Query: 1200 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ 1259
A+ AELGEQ+D+LQRV+QKLEKEKSE++ME+DDLA+N+ET+++AK + EK+CR EDQ
Sbjct: 1245 QAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQ 1304
Query: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL 1319
LSE K K EE QR + D + QR RLQTESGE SR L+EK+ L+SQLSRGK Q +EEL
Sbjct: 1305 LSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEEL 1364
Query: 1320 KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY 1379
+RQLEEE KAKSALAHA+Q+ RHDCDLLREQ+EEE EA+AELQR +SKAN+EVAQWR+KY
Sbjct: 1365 RRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 1424
Query: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT 1439
E DAIQRTEELEEAKKKLA RLQ+AEE VEA NAKC+SLEK K RLQ E ED+ +++ER
Sbjct: 1425 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 1484
Query: 1440 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQL 1499
+A AALDKKQR+ ++ L E +++ EE ELEA+Q+ESR L TELF++++ +EE+L+ L
Sbjct: 1485 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL 1544
Query: 1500 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEE 1559
ETLKRENKNLQ+EISDLT+Q++ GK I ELEK KK +E EKSE+QAALEEAE +LE EE
Sbjct: 1545 ETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEE 1604
Query: 1560 GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
K LRIQLEL+QVK+EVDRK+AEKDEE ++RNH R VES+Q++LDAE R+RN+A+RLK
Sbjct: 1605 TKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLK 1664
Query: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
KKMEGDLN++E+QL HA R A EA R QA LK+ Q D+ R +L EQ +E
Sbjct: 1665 KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1724
Query: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
RRA+LL AE+EELRA LEQ ERSR++AEQELL+A+ER+ LLH+QNT L+N KKKLE D++
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLA 1784
Query: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Q+ GE+E+ QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK LEQTV++LQ
Sbjct: 1785 QLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQA 1844
Query: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTE 1859
RL+EAEQ AL+GGKKQ+QKLEA+VRELE E+++EQK++ EA+KG+RKHER+VKEL YQ E
Sbjct: 1845 RLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAE 1904
Query: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAES 1919
EDRKN+ R+QDLVDKLQ+KVKSYKRQ EEAE+Q+N NL+K+R+ QHEL++AEERAD+AE+
Sbjct: 1905 EDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAET 1964
Query: 1920 QVNKLRVKSRE 1930
Q NKLR ++R+
Sbjct: 1965 QANKLRARTRD 1975
Score = 215 bits (548), Expect = 3e-55
Identities = 199/926 (21%), Positives = 421/926 (45%), Gaps = 56/926 (6%)
Query: 1029 IKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKE 1088
+KL ++ L S + E+++ L R L G L A+ ++E + ++
Sbjct: 879 MKLFFKMKPLLRSAQAEEELAA-LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLA 937
Query: 1089 FEMSGLQSKIEDEQAL-------GMQLQKKIKELQARIEELEEEIEAERASRA-KAEKQR 1140
++ Q + D + +QL+ K+KEL R+E+ EEE+ A+ A+R K E +
Sbjct: 938 LQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLED-EEEVNADLAARRRKLEDEC 996
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1200
++L ++++++ L +A K+++A K++ EE E+ A ++K
Sbjct: 997 TELKKDIDDLKLTLAKA----------EKEKQATENKVKNLTEEMAALDESVARLTKEKK 1046
Query: 1201 ADSVAELGEQIDNLQRVKQK---LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALE 1257
A A + + +LQ + + L K K ++ +++DL ++E K + + E+ R LE
Sbjct: 1047 ALQEAHQ-QALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLE 1105
Query: 1258 DQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIE 1317
L + + + L + + +E + S +++++ L +Q+ + + + E
Sbjct: 1106 GDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAE 1165
Query: 1318 ELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRT 1377
EL+ +LE E A++ + + + + L E+ EE A A + K +E+ + R
Sbjct: 1166 ELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRR 1225
Query: 1378 KYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 1437
+ E A++ + ++K A+ + E V+++ LEK K L+ EV+DL +VE
Sbjct: 1226 ELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285
Query: 1438 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD 1497
A A+ +K R ++ L+E K K EE +L + + L TE ++ EE
Sbjct: 1286 TLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKEC 1345
Query: 1498 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEH 1557
+ L R Q + +L Q+ E K L + + + L+ EE EA +
Sbjct: 1346 LISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE-EAEAQA 1404
Query: 1558 EEGKIL-RIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAI 1616
E ++L + E+ Q +S+ + ++ EE+++ K+ ++ + ++A +
Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464
Query: 1617 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLA 1676
+ K +++ + ++ ++L A AA + R+ + L++ + R +E+++ +L
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERR-------RQEEEMQRELE 1517
Query: 1677 MVERRANLLQAEI-------EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729
+R + L E+ EE LE +R K ++E+ D +++V L L
Sbjct: 1518 AAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEK 1577
Query: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKK 1788
TKK LE + S+IQ +E+ E K + + + + E+ +K + +++
Sbjct: 1578 TKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRR 1637
Query: 1789 NLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHE 1848
N ++ V+ LQ LD AE A + +K+E + +LE ++ ++ EA R +
Sbjct: 1638 NHQRAVESLQASLD-AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQ 1696
Query: 1849 RKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELE 1908
++KE +E+++ L + QA+ E ++++ ++ ++ LE
Sbjct: 1697 AQLKEEQAGRDEEQRLAAELHE--------------QAQALERRASLLAAELEELRAALE 1742
Query: 1909 EAEERADIAESQVNKLRVKSREVHTK 1934
+ E +AE ++ + + +H++
Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQ 1768
Score = 169 bits (428), Expect = 2e-41
Identities = 181/844 (21%), Positives = 372/844 (44%), Gaps = 107/844 (12%)
Query: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEK-------QRSDLSRELEEISERLEEAGG 1159
Q ++++ L+A + L + A A R + E+ +++DL+ +L+ + L +A
Sbjct: 893 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 952
Query: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
I+ + E + +++ LE+ + A A R+K D EL + ID+L+
Sbjct: 953 RCHLLIKSKVQLEGKVKELSERLEDEE-EVNADLAARRRKLEDECTELKKDIDDLKLTLA 1011
Query: 1220 KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTA 1279
K EKEK + ++ +L M + ++ L K +AL+ E Q+ + DL A
Sbjct: 1012 KAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQ----------EAHQQALGDLQA 1061
Query: 1280 QRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS 1339
+ R VS L++ K QQ+E+L+ LE+E K + A +
Sbjct: 1062 EEDR------------------VSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRK 1103
Query: 1340 SRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1399
D L +E + + K +L+ + K +SE++Q + E + + + +++ K+L
Sbjct: 1104 LEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQ-MQKKIKELQA 1162
Query: 1400 RLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAE 1459
R ++ EE +EA A A +EK + E+E+L +E A A + R + L
Sbjct: 1163 RAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGR 1222
Query: 1460 WKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1519
+++ EE EA+ + L+R+ E
Sbjct: 1223 LRRELEEAALRHEAT------------------------VAALRRKQ----------AEG 1248
Query: 1520 IAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRK 1579
AE G+++ L+++++++E+EKSEL+ +++ A++E L + K+ ++
Sbjct: 1249 AAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE-----------TLTRAKASAEKL 1297
Query: 1580 IAEKDEEIDQMKRNHIRIVESMQSTLDAEI---RSRNDAIRLKKKMEGDLNEMEIQLNHA 1636
++++ + K I++ E + DA R + ++ L + +E + + QL+
Sbjct: 1298 CRTYEDQLSEAK---IKVEELQRQLADASTQRGRLQTESGELSRLLE-EKECLISQLSRG 1353
Query: 1637 NRMAAEALRNYRNT---QAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELR 1693
+AA++L R ++ K H ALR DL + E A QAE++ L
Sbjct: 1354 KALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEA---QAELQRLL 1410
Query: 1694 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEAR 1753
+ + + ++A+ ++ +Q + L KKKL + + + +E +
Sbjct: 1411 S-----KANAEVAQWRSKYEADAIQ----RTEELEEAKKKLALRLQEAEEGVEAANAKCS 1461
Query: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
+ E+ + T++ + EL++ +A L++ +++LE+ +++ + R +E Q L+ +
Sbjct: 1462 SLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEE-RRRQEEEMQRELEAAQ 1520
Query: 1814 KQIQKLEARVRELEGEVESEQKRNVEAVKGLRKH-ERKVKELTYQTEEDRKNILRLQDLV 1872
++ + L + L E E +E +K K+ + ++ +LT Q K+I L+
Sbjct: 1521 RESRGLGTELFRLRHGHE-EALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTK 1579
Query: 1873 DKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVH 1932
L+ + + EEAE + +K RIQ EL + + D ++ ++ R H
Sbjct: 1580 KALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNH 1639
Query: 1933 TKII 1936
+ +
Sbjct: 1640 QRAV 1643
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 2308 bits (5981), Expect = 0.0
Identities = 1144/1934 (59%), Positives = 1535/1934 (79%), Gaps = 10/1934 (0%)
Query: 6 EMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQ-SREGGKVTAKT 64
+++ GEAA FLR+SE E + Q D K ++ D + ++++A V+ S + G V +T
Sbjct: 22 DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
Query: 65 EAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
G ++++K+D++ MNPP+++ IEDMAM+THL+E +VL+ LK RY WMIYTYSGLFCV
Sbjct: 82 ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
Query: 125 TVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
T+NPYKWLPVY EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 142 TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
Query: 185 KTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNS 244
KTVN+K +IQYFATIA E +K+ QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 202 KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254
Query: 245 SRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEML 304
SRFGKFIR+HFG G L+S DI+ YLLEKSRV FQ ER+YHIFYQI+S +K +L ++L
Sbjct: 255 SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313
Query: 305 LITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGN 364
L++ NP D+ F S G +TV S+DD EEL+AT+ A++ILGF DE+ YKLTGA+MH+GN
Sbjct: 314 LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373
Query: 365 MKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVY 424
MKFKQK REEQ E DGTE ADKAA+L +NS++L+K L +PR+KVGNEYVT+GQT++QV
Sbjct: 374 MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433
Query: 425 NAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484
AVGAL+K++Y++MF W+V RIN+ LD K RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 434 CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493
Query: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544
NEKLQQFFN HMFVLEQEEYKKE IEW I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 494 NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553
Query: 545 KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPL 604
KATD +FK KL++ H GKS + QKPKP K K EAHF L+HYAG V YNI+GWL+KNKD L
Sbjct: 554 KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613
Query: 605 NETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664
NETVV ++QKS+ + LA LF ++ G+K +KKG+SFQTV++L +ENLNKLMT
Sbjct: 614 NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK-RKKGASFQTVASLHKENLNKLMT 672
Query: 665 NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724
NL+ST PHFVRCI PN K PG ++ LVL QLRCNGVLEG RICR+GFP+R+ YADFKQ
Sbjct: 673 NLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQ 732
Query: 725 RYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEK 784
RY +LN P+ +F+ S+KA+E+LLGS++IDHTQY+FG TKVFFKAG LG LE +RDE+
Sbjct: 733 RYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDER 792
Query: 785 LAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLL 844
L+++ T QA +G L R+++QK++E R+++ IQ+N+RAFM VK+WPWM+L+FKIKPL+
Sbjct: 793 LSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLV 852
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
KS+E +E+A +KEE + ++ L K+E +R+EL+ K V+L QEKNDL LQ+QAE ++LA+
Sbjct: 853 KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE
Sbjct: 913 VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 972
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
L K EKEK TE+KVKNLTEE+ L+E I+KL + K +QEAHQQTLDDL EE+K+++L
Sbjct: 973 LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032
Query: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKL 1084
+KA +KLEQQVD+LEG+LEQE+K RM+ ER KLEG+LKL +ES ++E+ ++ L E+L
Sbjct: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092
Query: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
+KKE E+S + SK+E+E+ L QLQK +KELQ +I++L+E++EAER +RAK E++R+DL+
Sbjct: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152
Query: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1204
++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EEATL E T+A+L+K+HADS+
Sbjct: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL 1212
Query: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
AEL Q++NLQ+VKQKLEK+KS++++E+DDL + +E +++AK N EK+C E++L E
Sbjct: 1213 AELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEAT 1272
Query: 1265 TKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLE 1324
K ++ +L NDL AQ+ +L +ESGE+ R+L+EK+ L++QLSR K FT+QIE+L+ QLE
Sbjct: 1273 AKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLE 1332
Query: 1325 EEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAI 1384
+E K++SALAHALQ ++ DCDLLREQYEEEQE KAEL R +SK N+E+ QWR KYE + I
Sbjct: 1333 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1392
Query: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACA 1444
QRTE+LE+AKK+LA RLQ+A E + NA+ ASLE+ + +LQ E+ D + D+ + +A A
Sbjct: 1393 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1452
Query: 1445 ALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR 1504
LD+KQ K LA+WKQK EE+ A L+ASQKE ++LSTEL K+KN YEES+ ETL+R
Sbjct: 1453 RLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRR 1512
Query: 1505 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILR 1564
ENKNLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK+E+Q LEE E +LE E KIL
Sbjct: 1513 ENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILH 1572
Query: 1565 IQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEG 1624
QLEL + K+E++RK++EKDEEI+ +R ++S+QS+LD+E +SR + RLKKKME
Sbjct: 1573 FQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEE 1632
Query: 1625 DLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANL 1684
DLNEME+QL+ ANR +EA ++ Q +KD Q+ LDD+ + DLKEQ+A+ ERR +L
Sbjct: 1633 DLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 1692
Query: 1685 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744
LQ+E+E+LR+ EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D++++Q E
Sbjct: 1693 LQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
Query: 1745 MEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804
E+++QE +NAEEKAKKA +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EA
Sbjct: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEA 1812
Query: 1805 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKN 1864
EQ+AL G +KQIQKLE+RVRELEGE+E E +R+ EA +G R+ ER +KELTYQ EED+KN
Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN 1872
Query: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKL 1924
+ R+Q +DKLQ KV++YK+Q E AE Q+N LSK+++ QHEL E +ERA++AESQVNKL
Sbjct: 1873 LSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKL 1932
Query: 1925 RVKSREVHTKIISE 1938
++K+RE K+ E
Sbjct: 1933 KIKAREFGKKVQEE 1946
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 1421 bits (3678), Expect = 0.0
Identities = 779/1911 (40%), Positives = 1187/1911 (62%), Gaps = 21/1911 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92
AK V+V K+ F A+++ +G +V + E G VTV D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE-EVT 211
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +T
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 212 SGKM--QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269
G G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY
Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271
Query: 270 LLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQ 329
LLEKSR Q + ER++HIFY +++ K + LL+ +Y F+S G + +P+ D
Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330
Query: 330 EELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
E T A+ I+GF+ +E++SI K+ +V+ GN+ FK+++ +QA A K +
Sbjct: 331 EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390
Query: 390 LQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQ 449
L +N D +++ PR+KVG + V K QT +Q AV ALAKA Y+++F W++TR+N+
Sbjct: 391 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450
Query: 450 LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510
Query: 509 IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
IEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G
Sbjct: 511 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569
Query: 566 FQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF- 624
FQKPK K K E FS+IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 570 FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627
Query: 625 -----VGATG-AEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 678
VG A+ K K F+TV L++E L KLMT LR+T P+FVRCII
Sbjct: 628 DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687
Query: 679 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 738
PN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G
Sbjct: 688 PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746
Query: 739 FIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRG 798
F+D K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QAMCRG
Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806
Query: 799 FLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
+LAR + K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++
Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866
Query: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQ 918
E +KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +
Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 919 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 978
LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986
Query: 979 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1038
+K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +L
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Query: 1039 EGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKI 1098
E L++E+K R +LE+ KRKLEGD E D++ +L +L KKE E+ +++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106
Query: 1099 EDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
+DE A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 1159 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1218
+T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 1219 QKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLT 1278
L+K K ++ E DLA + + +AK +E + LE Q+ E+++K + +R +L
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 1279 AQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQ 1338
+ +LQ E + L+E + +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 1339 SSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405
Query: 1399 QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILA 1458
+ +++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1459 EWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1518
E K + E + ++ E+R T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 1519 QIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1578
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 1579 KIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1638
+ +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 1639 MAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1698
EA++ R QA +KD Q L+DA S++++ E++A L+A++ +L+ L
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 1699 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEK 1758
ER+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
+KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 1819 LEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
LEA++ +LE +VE E + A K L++ ++K+KE+ Q E++RK + ++ +K A+
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885
Query: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
VK KRQ EEAEE+S + R++Q EL+EA E + +VN L+ K R
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 216 bits (549), Expect = 2e-55
Identities = 193/901 (21%), Positives = 423/901 (46%), Gaps = 51/901 (5%)
Query: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1197
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 1198 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCR 1254
+ + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+
Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037
Query: 1255 ALEDQLSE--IKTKEEEQQRL------------INDLTAQRARLQTESGEYSRQLDEKDT 1300
E +SE ++ K+EE+ R +D Q A LQ + E QL +K+
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 1301 -LVSQLSRGKQAFTQQIEELKR---------QLEEEIKAKSALAHALQSSRHDC----DL 1346
L + L+R Q+ LK+ L+E++ ++ A + + + D +
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
L+ + E+ ++ A Q +K EV + + + +++E ++K AQ +++ E
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
+E A+L+K KQ L+ E DL ++ A ++ K++ + + E + KC +
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
+ L E+ + E+ + L ++ +L ++ D E + E ++
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1337
Query: 1527 IHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1586
+ +Q+E+E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1338 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1396
Query: 1587 IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
+++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + +
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 1647 YRNTQAILKD----TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1702
R +L + + + D+ R++ + +E+ E +A L +EE E+ ER+
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1512
Query: 1703 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEE-KAKK 1761
K+ + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ L++ + + + L DE +Q AL K+ KLE
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1630
Query: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV--NKLRVKSREVHTKIISE 1938
S +A+ + Q ++ ++ R Q +LE+ E ++A S N L+ + R + +I
Sbjct: 1691 SL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 1939 E 1939
E
Sbjct: 1749 E 1749
Score = 98.2 bits (243), Expect = 7e-20
Identities = 86/366 (23%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
K + ++++ + E E +++ A A +K+LE + DL+LQ ADS
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQ----ADSAIK 1645
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
E + IK +L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 1646 GRE---EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 1025 TKAKIKLEQQVDDLEGSLEQEKKI-------RMDLERAKRKL-------EGDLKLAQEST 1070
+ K QQ + L L E+ R LER ++L EG +K +ST
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822
Query: 1071 M-----DIENDKQQLDEKLKKKEFEMSGLQSK----------IEDEQALGMQLQKKIKEL 1115
+ I ++Q++++ ++K+ L+ K +EDE+ + Q +++ ++
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882
Query: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1174
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1942
Query: 1175 FQKMRR 1180
F RR
Sbjct: 1943 FVPSRR 1948
Score = 72.8 bits (177), Expect = 3e-12
Identities = 57/277 (20%), Positives = 121/277 (43%), Gaps = 12/277 (4%)
Query: 1666 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1722
R +E+++ ++L + R + E++EL Q + + +++L +E
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 1723 QNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782
L K++LE + +++ +E+ + + + KK + E+L++E+
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 1783 LERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNV 1838
L+ K E +K L+ + D+ +L+ K+ + LE R+ +L + E+++
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKAK 1030
Query: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 1899 KFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
+ + + EL+ A R D +Q N K RE+ I
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 1421 bits (3678), Expect = 0.0
Identities = 779/1911 (40%), Positives = 1187/1911 (62%), Gaps = 21/1911 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92
AK V+V K+ F A+++ +G +V + E G VTV D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE-EVT 211
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +T
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 212 SGKM--QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269
G G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY
Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271
Query: 270 LLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQ 329
LLEKSR Q + ER++HIFY +++ K + LL+ +Y F+S G + +P+ D
Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330
Query: 330 EELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
E T A+ I+GF+ +E++SI K+ +V+ GN+ FK+++ +QA A K +
Sbjct: 331 EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390
Query: 390 LQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQ 449
L +N D +++ PR+KVG + V K QT +Q AV ALAKA Y+++F W++TR+N+
Sbjct: 391 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450
Query: 450 LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510
Query: 509 IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
IEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G
Sbjct: 511 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569
Query: 566 FQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF- 624
FQKPK K K E FS+IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 570 FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627
Query: 625 -----VGATG-AEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 678
VG A+ K K F+TV L++E L KLMT LR+T P+FVRCII
Sbjct: 628 DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687
Query: 679 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 738
PN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G
Sbjct: 688 PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746
Query: 739 FIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRG 798
F+D K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QAMCRG
Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806
Query: 799 FLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
+LAR + K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++
Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866
Query: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQ 918
E +KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +
Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 919 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 978
LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986
Query: 979 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1038
+K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +L
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Query: 1039 EGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKI 1098
E L++E+K R +LE+ KRKLEGD E D++ +L +L KKE E+ +++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106
Query: 1099 EDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
+DE A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 1159 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1218
+T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 1219 QKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLT 1278
L+K K ++ E DLA + + +AK +E + LE Q+ E+++K + +R +L
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 1279 AQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQ 1338
+ +LQ E + L+E + +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 1339 SSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405
Query: 1399 QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILA 1458
+ +++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1459 EWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1518
E K + E + ++ E+R T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 1519 QIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1578
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 1579 KIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1638
+ +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 1639 MAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1698
EA++ R QA +KD Q L+DA S++++ E++A L+A++ +L+ L
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 1699 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEK 1758
ER+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
+KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 1819 LEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
LEA++ +LE +VE E + A K L++ ++K+KE+ Q E++RK + ++ +K A+
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885
Query: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
VK KRQ EEAEE+S + R++Q EL+EA E + +VN L+ K R
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 216 bits (549), Expect = 2e-55
Identities = 193/901 (21%), Positives = 423/901 (46%), Gaps = 51/901 (5%)
Query: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1197
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 1198 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCR 1254
+ + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+
Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037
Query: 1255 ALEDQLSE--IKTKEEEQQRL------------INDLTAQRARLQTESGEYSRQLDEKDT 1300
E +SE ++ K+EE+ R +D Q A LQ + E QL +K+
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 1301 -LVSQLSRGKQAFTQQIEELKR---------QLEEEIKAKSALAHALQSSRHDC----DL 1346
L + L+R Q+ LK+ L+E++ ++ A + + + D +
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
L+ + E+ ++ A Q +K EV + + + +++E ++K AQ +++ E
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
+E A+L+K KQ L+ E DL ++ A ++ K++ + + E + KC +
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
+ L E+ + E+ + L ++ +L ++ D E + E ++
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1337
Query: 1527 IHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1586
+ +Q+E+E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1338 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1396
Query: 1587 IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
+++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + +
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 1647 YRNTQAILKD----TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1702
R +L + + + D+ R++ + +E+ E +A L +EE E+ ER+
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1512
Query: 1703 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEE-KAKK 1761
K+ + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ L++ + + + L DE +Q AL K+ KLE
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1630
Query: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV--NKLRVKSREVHTKIISE 1938
S +A+ + Q ++ ++ R Q +LE+ E ++A S N L+ + R + +I
Sbjct: 1691 SL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 1939 E 1939
E
Sbjct: 1749 E 1749
Score = 72.8 bits (177), Expect = 3e-12
Identities = 57/277 (20%), Positives = 121/277 (43%), Gaps = 12/277 (4%)
Query: 1666 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1722
R +E+++ ++L + R + E++EL Q + + +++L +E
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 1723 QNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782
L K++LE + +++ +E+ + + + KK + E+L++E+
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 1783 LERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNV 1838
L+ K E +K L+ + D+ +L+ K+ + LE R+ +L + E+++
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKAK 1030
Query: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 1899 KFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
+ + + EL+ A R D +Q N K RE+ I
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 1420 bits (3676), Expect = 0.0
Identities = 777/1908 (40%), Positives = 1186/1908 (62%), Gaps = 22/1908 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92
AK V+V K+ F A+++ +G +V + E G VTV D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTS 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 212 GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 273 KSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEEL 332
KSR Q + ER++HIFY +++ K + LL+ +Y F+S G + +P+ D E
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
Query: 333 MATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQN 392
T A+ I+GF+ +E++SI K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
Query: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD- 451
+N D +++ PR+KVG + V K QT +Q AV ALAKA Y+++F W++TR+N+ LD
Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
Query: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
Query: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
Query: 569 PKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF---- 624
PK K K E FS+IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 625 --VGATG-AEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681
VG A+ K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 682 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 742 SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLA 801
K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QAMCRG+LA
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 802 RVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861
R + K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++E +
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 921
KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1041
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE 1101
L++E+K R +LE+ KRKLEGD E D++ +L +L KKE E+ ++++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1102 QALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQR 1281
+K K ++ E DLA + + +AK +E + LE Q+ E+++K + +R +L +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSR 1341
+LQ E + L+E + +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1342 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
+ E + ++ E+R T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 1522 EGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1582 EKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
+DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
EA++ R QA +KD Q L+DA S++++ E++A L+A++ +L+ L ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1702 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761
+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1821
A A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LEA
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
Query: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
++ +LE +VE E + A K L++ ++K+KE+ Q E++RK + ++ +K A+VK
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 1882 YKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
KRQ EEAEE+S + R++Q EL+EA E + +VN L+ K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 216 bits (549), Expect = 2e-55
Identities = 193/901 (21%), Positives = 423/901 (46%), Gaps = 51/901 (5%)
Query: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1197
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 1198 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCR 1254
+ + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+
Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
Query: 1255 ALEDQLSE--IKTKEEEQQRL------------INDLTAQRARLQTESGEYSRQLDEKDT 1300
E +SE ++ K+EE+ R +D Q A LQ + E QL +K+
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 1301 -LVSQLSRGKQAFTQQIEELKR---------QLEEEIKAKSALAHALQSSRHDC----DL 1346
L + L+R Q+ LK+ L+E++ ++ A + + + D +
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
L+ + E+ ++ A Q +K EV + + + +++E ++K AQ +++ E
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
+E A+L+K KQ L+ E DL ++ A ++ K++ + + E + KC +
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
+ L E+ + E+ + L ++ +L ++ D E + E ++
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
Query: 1527 IHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1586
+ +Q+E+E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1389
Query: 1587 IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
+++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + +
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 1647 YRNTQAILKD----TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1702
R +L + + + D+ R++ + +E+ E +A L +EE E+ ER+
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1505
Query: 1703 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEE-KAKK 1761
K+ + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ L++ + + + L DE +Q AL K+ KLE
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1623
Query: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV--NKLRVKSREVHTKIISE 1938
S +A+ + Q ++ ++ R Q +LE+ E ++A S N L+ + R + +I
Sbjct: 1684 SL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 1939 E 1939
E
Sbjct: 1742 E 1742
Score = 98.2 bits (243), Expect = 7e-20
Identities = 86/366 (23%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
K + ++++ + E E +++ A A +K+LE + DL+LQ ADS
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQ----ADSAIK 1638
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
E + IK +L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 1639 GRE---EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 1025 TKAKIKLEQQVDDLEGSLEQEKKI-------RMDLERAKRKL-------EGDLKLAQEST 1070
+ K QQ + L L E+ R LER ++L EG +K +ST
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
Query: 1071 M-----DIENDKQQLDEKLKKKEFEMSGLQSK----------IEDEQALGMQLQKKIKEL 1115
+ I ++Q++++ ++K+ L+ K +EDE+ + Q +++ ++
Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
Query: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1174
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
Query: 1175 FQKMRR 1180
F RR
Sbjct: 1936 FVPSRR 1941
Score = 72.8 bits (177), Expect = 3e-12
Identities = 57/277 (20%), Positives = 121/277 (43%), Gaps = 12/277 (4%)
Query: 1666 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1722
R +E+++ ++L + R + E++EL Q + + +++L +E
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 1723 QNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782
L K++LE + +++ +E+ + + + KK + E+L++E+
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 1783 LERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNV 1838
L+ K E +K L+ + D+ +L+ K+ + LE R+ +L + E+++
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKAK 1023
Query: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 1899 KFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
+ + + EL+ A R D +Q N K RE+ I
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 1420 bits (3676), Expect = 0.0
Identities = 777/1908 (40%), Positives = 1186/1908 (62%), Gaps = 22/1908 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92
AK V+V K+ F A+++ +G +V + E G VTV D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTS 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 212 GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 273 KSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEEL 332
KSR Q + ER++HIFY +++ K + LL+ +Y F+S G + +P+ D E
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
Query: 333 MATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQN 392
T A+ I+GF+ +E++SI K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
Query: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD- 451
+N D +++ PR+KVG + V K QT +Q AV ALAKA Y+++F W++TR+N+ LD
Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
Query: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
Query: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
Query: 569 PKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF---- 624
PK K K E FS+IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 625 --VGATG-AEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681
VG A+ K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 682 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 742 SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLA 801
K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QAMCRG+LA
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 802 RVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861
R + K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++E +
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 921
KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1041
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE 1101
L++E+K R +LE+ KRKLEGD E D++ +L +L KKE E+ ++++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1102 QALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQR 1281
+K K ++ E DLA + + +AK +E + LE Q+ E+++K + +R +L +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSR 1341
+LQ E + L+E + +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1342 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
+ E + ++ E+R T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 1522 EGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1582 EKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
+DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
EA++ R QA +KD Q L+DA S++++ E++A L+A++ +L+ L ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1702 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761
+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1821
A A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LEA
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
Query: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
++ +LE +VE E + A K L++ ++K+KE+ Q E++RK + ++ +K A+VK
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 1882 YKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
KRQ EEAEE+S + R++Q EL+EA E + +VN L+ K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 216 bits (549), Expect = 2e-55
Identities = 193/901 (21%), Positives = 423/901 (46%), Gaps = 51/901 (5%)
Query: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1197
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 1198 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCR 1254
+ + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+
Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
Query: 1255 ALEDQLSE--IKTKEEEQQRL------------INDLTAQRARLQTESGEYSRQLDEKDT 1300
E +SE ++ K+EE+ R +D Q A LQ + E QL +K+
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 1301 -LVSQLSRGKQAFTQQIEELKR---------QLEEEIKAKSALAHALQSSRHDC----DL 1346
L + L+R Q+ LK+ L+E++ ++ A + + + D +
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
L+ + E+ ++ A Q +K EV + + + +++E ++K AQ +++ E
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
+E A+L+K KQ L+ E DL ++ A ++ K++ + + E + KC +
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
+ L E+ + E+ + L ++ +L ++ D E + E ++
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
Query: 1527 IHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1586
+ +Q+E+E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1389
Query: 1587 IDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRN 1646
+++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + +
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 1647 YRNTQAILKD----TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1702
R +L + + + D+ R++ + +E+ E +A L +EE E+ ER+
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1505
Query: 1703 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEE-KAKK 1761
K+ + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ L++ + + + L DE +Q AL K+ KLE
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1623
Query: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV--NKLRVKSREVHTKIISE 1938
S +A+ + Q ++ ++ R Q +LE+ E ++A S N L+ + R + +I
Sbjct: 1684 SL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 1939 E 1939
E
Sbjct: 1742 E 1742
Score = 72.8 bits (177), Expect = 3e-12
Identities = 57/277 (20%), Positives = 121/277 (43%), Gaps = 12/277 (4%)
Query: 1666 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1722
R +E+++ ++L + R + E++EL Q + + +++L +E
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 1723 QNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782
L K++LE + +++ +E+ + + + KK + E+L++E+
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 1783 LERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNV 1838
L+ K E +K L+ + D+ +L+ K+ + LE R+ +L + E+++
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKAK 1023
Query: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 1899 KFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
+ + + EL+ A R D +Q N K RE+ I
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 1405 bits (3637), Expect = 0.0
Identities = 770/1909 (40%), Positives = 1178/1909 (61%), Gaps = 27/1909 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92
AK V+V K F A+++ G + + E G V V D + MNPPK+ K+EDMA
Sbjct: 28 AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152
+T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y+ E+V Y+GKKR E P
Sbjct: 88 ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTS 212
PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+
Sbjct: 148 PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
Query: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLE
Sbjct: 204 ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260
Query: 273 KSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYD-YAFVSQGEITVPSIDDQEE 331
KSR Q K ER++HIFY ++S L LL+ PY+ Y F+S G +T+P D++
Sbjct: 261 KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318
Query: 332 LMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQ 391
T A+ I+G +E++ + ++ V+ GN+ FK+++ +QA A K ++L
Sbjct: 319 FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378
Query: 392 NLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD 451
+N D + + PR+KVG +YV K QT +Q A+ ALAKA Y++MF W+V RIN+ LD
Sbjct: 379 GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438
Query: 452 -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
TK+ FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 439 KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
Query: 511 WTFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
W FIDFG+DL CI+LIEKP G I ++L+EEC FPKATD SF K+ ++ G FQ
Sbjct: 499 WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQ 557
Query: 568 KPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLFVGA 627
KPK K K A F +IHYAG VDY WL KN DPLN+ + L +S+ K ++ L+
Sbjct: 558 KPKQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615
Query: 628 T---GAEAEAGGGKKG----GKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680
G + AG + K + F+TV L++E L KLM LR+T+P+FVRCIIPN
Sbjct: 616 DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
Query: 681 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740
K G ++ LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L ++IP+G F+
Sbjct: 676 HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734
Query: 741 DSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFL 800
D K+A ++ ++++D Y+ G +KVFF+AG+L LEE RD K+ +I QA CRG+L
Sbjct: 735 DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794
Query: 801 ARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860
AR + K ++ ++ +Q N A++ +++W W +L+ K+KPLL+ + E+EM +EE
Sbjct: 795 ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
Query: 861 EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLE 920
K +E+ E + E+E LM EK LQ Q+QAE + A+AEE +L K +LE
Sbjct: 855 VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
Query: 921 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980
++ R E+EEE L A+K+K++ EL++ +++ E K++ EK TE K+K
Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1040
L EE L++ KL KEKK L++ + +L EE+K +L K K K E + DLE
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100
L +E+K R +LE+ +RKLEGD + +++ +L +L KKE E+ +++E+
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094
Query: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
E A KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL ELE + LE+ +
Sbjct: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
Query: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
T+AQ E+ KRE E +++ LEE HEA +R+KH+ +V EL EQ++ +RVK
Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
LEK K ++ E +LA+ ++ + + KG+ E + +E QL E++ K E +R+ +L +
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340
+LQ E + L + D+ S+L++ A Q+++ + L+EE + K +L+ L+
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
+ + REQ EEE+EAK L++ ++ +++VA + K E D++ E EE K+KL +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393
Query: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460
L+ + E A LEKTK RLQ E++DL++D++ + L+KKQ+ FD++LAE
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
Query: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520
K + E + ++ E+R T+ + A EE+++Q L+R NK + E+ DL
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
Query: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
+ GK +HELEK K+ +EQ+ E++ LEE E L+ E LR+++ L +K++ +R +
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
Query: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
+DE+ ++ K+ +R V M++ L+ E + R+ A+ +KK+E DL ++E ++ AN+
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
Query: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700
EA++ R QA +KD LDD S+E++ Q E++ ++AE+ +L+ L E
Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693
Query: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760
R+++ A+QE + ++ + + + K++LE I+Q++ E+E+ ++ K
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753
Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
KA + +L E+ + E ++ LE+ K+L+ +L E E K I LE
Sbjct: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813
Query: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880
A++ +LE ++++E K A K +R+ E+K+K++ Q +++R+N + +D DK ++K
Sbjct: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873
Query: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
KRQ EEAEE++ + R++Q ELE+A E AD +V+ L+ K R
Sbjct: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 265 bits (677), Expect = 3e-70
Identities = 240/996 (24%), Positives = 463/996 (46%), Gaps = 109/996 (10%)
Query: 835 KLYFKIKPLLKSAETEKEMANMKEEFEK--TKEELAKTEAKRKELEEKMVTLMQEKNDLQ 892
K+ I+ L + E E+E A K + EK T+ +L K E ++ LE++ L +EK L+
Sbjct: 940 KMQQNIQELEEQLE-EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 893 LQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE---- 948
++ +L + EE+ L K K + EA I ++ ER EE+ EL +RKLE
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 949 ---DECSELKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDE 991
D+ +EL+ I +L++ LAK E+E K+ K++ L +++ L E
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 992 TIAK--------------LTKEKKALQEAHQQTLDDLQAE-------EDKVNTLTKA--- 1027
+ L +E +AL+ + TLD A+ E +VN L K
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 1028 ------------KIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL-KLAQESTMDIE 1074
+ K Q V++L LEQ K+++ +LE+AK+ LE + +LA E + ++
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 1075 NDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRA 1134
K + K KK E ++ LQ K + + + +L K+ +LQ ++ + + + +
Sbjct: 1239 G-KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSS 1297
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE---------- 1184
K K S L +L++ E L+E + K+ E E R LEE
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
Query: 1185 --ATLQHEATAATLRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEKEK 1225
ATL A A ++KK DSV E E++ +L+ + Q KLEK K
Sbjct: 1358 QIATLH--AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTK 1415
Query: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285
+ ++ E+DDL +++ ++ NLEK + + L+E KT + + A+ +
Sbjct: 1416 TRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKE 1475
Query: 1286 TESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1345
T++ +R L+E ++L R + F ++E+L ++ K+ L + ++ +
Sbjct: 1476 TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVE 1535
Query: 1346 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1405
++ Q EE ++ + A + + + ++E D R E+ EE KK+L +++++ E
Sbjct: 1536 EMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME 1595
Query: 1406 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCE 1465
+E + + +++L+ +++DL ++ N K+ R + + ++ +
Sbjct: 1596 AELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELD 1655
Query: 1466 ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG-G 1524
+T A E +++ +L ++ + ++L +R + QQE +L ++IA G
Sbjct: 1656 DTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSG 1715
Query: 1525 KRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAE 1582
K LE+ K+++E ++L+ LEE + + E ++ + L+++Q+ +++ +R A+
Sbjct: 1716 KGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQ 1774
Query: 1583 KDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK-----MEGDLNEMEIQLNHAN 1637
K+E Q +E L +++ ++ K K +E + ++E QL++
Sbjct: 1775 KNENARQQ-------LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET 1827
Query: 1638 RMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLE 1697
+ A + R T+ LKD L +DD R+ E K+Q R L+ ++EE +
Sbjct: 1828 KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1887
Query: 1698 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733
+ SR+ ++EL DA+E ++ + +SL N ++
Sbjct: 1888 RANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
Score = 235 bits (600), Expect = 3e-61
Identities = 199/984 (20%), Positives = 462/984 (46%), Gaps = 94/984 (9%)
Query: 997 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056
TK K LQ + Q+ +++ A+E+++ + + ++ E ++ ++E ++ L K
Sbjct: 832 TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882
Query: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116
+L+ L+ E + E + +L K ++ E L++++E+E+ LQ + K++Q
Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1173
I+ELEE++E E ++R K + ++ +L+++ E LE+ + + ++ + R A
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 1174 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
EF + EE + + A L+ KH + +L E++ ++ +Q+LEK + +++ +
Sbjct: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 1234 DLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSR 1293
DL+ + + L+ E++L + EE+ N + L+++ E
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 1294 QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353
L+ + ++ + K+ +++E LK +LE+ + + +A + ++L++ EE
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 1354 EQEAKA----ELQRAMSKANSEVAQW-----RTKYETDAIQRTEELEEAK-----KKLAQ 1399
E + E+++ S+A E+A+ R K + ++T E E + K L Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 1400 RLQDAEEHVEAVNAKCASL-------EKTKQRLQNEVEDLMIDVERTNAACAALDKKQRN 1452
D+E + V A+ L E+ + L ++V L ++++ + D K
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 1453 FDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQE 1512
K + + + ++T L+ ++ SLST+L ++++ +QLE + NL+++
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Query: 1513 ISDLTEQIAEGGKRIHE-------LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRI 1565
I+ L Q+A+ K++ + E++K++++++ L EE A+ + E R+
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
Query: 1566 QLELNQVKSEVDRK------IAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
Q EL+ + ++D + + +K ++ DQ+ + T+ A+ D
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAE--------EKTISAKYAEERD----- 1465
Query: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
+ E + E E + R EA+ + + K + ++D + S++D+ + + +E
Sbjct: 1466 -RAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
+ L+ ++EE++ LE+ E + L A+E + K +LE ++
Sbjct: 1525 KSKRALEQQVEEMKTQLEELE--------DELQATE-------------DAKLRLEVNLQ 1563
Query: 1740 QIQGEME-DIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798
++ + E D+ +EEK K+ + M EL+ E+ + +K LE +KDL+
Sbjct: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 1799 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQT 1858
+D A + + KQ++KL+A++++ E++ + E + +++E+K+K + +
Sbjct: 1624 AHIDSANKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Query: 1859 EEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAE 1911
+ ++ + + Q D+L ++ + + A E+ ++ +++ ELEE +
Sbjct: 1683 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 1912 ERADIAESQVNKLRVKSREVHTKI 1935
++ ++ K ++ +++T +
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDL 1766
Score = 183 bits (464), Expect = 2e-45
Identities = 201/852 (23%), Positives = 370/852 (43%), Gaps = 73/852 (8%)
Query: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
+L K+K L ++ EEE+ A+ K +++ L E+ E L+ A Q++
Sbjct: 829 RLFTKVKPL-LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEM-ETLQSQLMAEKLQLQ 886
Query: 1167 MNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA-ELGEQIDNLQRVKQKLEKEK 1225
+ E E +L T +K+ + + +L +++ + Q L+ EK
Sbjct: 887 EQLQAETELCAEAEELR--------ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK 938
Query: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKE-EEQQRLIND----LTAQ 1280
+M+ I +L +E A+ L+ LE +E K K+ EE+Q ++ D L +
Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQ-----LEKVTTEAKLKKLEEEQIILEDQNCKLAKE 993
Query: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340
+ L+ E++ L E++ L++ K I +L+ +L E K + L +
Sbjct: 994 KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
D L +Q E Q AEL+ ++K E+ + E +A Q+ L++ ++ L +
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRE-LESQ 1112
Query: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460
+ + +E +E+ A EK K+ L E+E L ++E T + AA + + ++ +
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520
K+ EE EA +E R K A EE +QLE KR NL++ L +
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQ------KHSQAVEELAEQLEQTKRVKANLEKAKQTLENER 1226
Query: 1521 AEGGKRIHEL-------EKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVK 1573
E + L E +K+VE + ELQ E E K+ ++Q+EL+ V
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 1286
Query: 1574 SEVDRKIAEKDEEIDQMKRNHIRIVESMQST---LDAEIRSRNDAIRLKKKMEGDLNEME 1630
+++ D + ++ ++ + +Q T L E R + K++E + N
Sbjct: 1287 G----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 1631 IQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1690
QL + A + D + ++D++ E +E +++ L E
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHE 1402
Query: 1691 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI-- 1748
E A ++ E+++ +QEL D V L H Q S N +KK + Q+ E + I
Sbjct: 1403 EKVAAYDKLEKTKTRLQQELDDLL--VDLDH-QRQSACNLEKK-QKKFDQLLAEEKTISA 1458
Query: 1749 --IQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1806
+E AE +A++ T A +A L++ + A LER+ K ++DL D+
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG- 1517
Query: 1807 LALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNIL 1866
K + +LE R LE +VE E K +E + E Q ED K L
Sbjct: 1518 -------KSVHELEKSKRALEQQVE-EMKTQLEEL-----------EDELQATEDAK--L 1556
Query: 1867 RLQDLVDKLQAKV-KSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLR 1925
RL+ + ++A+ + + + E++EE+ + + R ++ ELE+ ++ +A + KL
Sbjct: 1557 RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLE 1616
Query: 1926 VKSREVHTKIIS 1937
+ +++ I S
Sbjct: 1617 MDLKDLEAHIDS 1628
Score = 155 bits (391), Expect = 5e-37
Identities = 147/646 (22%), Positives = 297/646 (45%), Gaps = 51/646 (7%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
KS++ K+ + ++ + + T+E L + ++ L K+ + EKN + Q++ E ++ +
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL--------------TAKKRKLEDE 950
E++ L ++ K+++ E EE+ +L A KLE
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 951 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK-KALQEAHQQ 1009
+ L++++DDL + L + E K K + +A AK +E+ +A EA ++
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
Query: 1010 TLDDL-------QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD 1062
L +A E K L + + +++DL S + K +LE++KR LE
Sbjct: 1475 ETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
Query: 1063 LKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIE-DEQALGMQLQKKIKELQARIEE 1121
++ + ++E++ Q ++ + E + ++++ E D Q Q ++K K+L ++ E
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 1122 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1181
+E E+E ER R+ A R L +L+++ ++ A I+ +K +A+ + R+
Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
Query: 1182 LEEATLQHEATAATLR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
L++ E A + K + +L E++ +R K++ ++E+ E+ EI +
Sbjct: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
Query: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295
+ + K LE LE++L E E+ LIND ++A LQ + + + L
Sbjct: 1714 SGKGALALEEKRRLEARIAQLEEELEE----EQGNTELIND-RLKKANLQID--QINTDL 1766
Query: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEE-EIKAKSALAHALQSSRHDCDLLREQYE-- 1352
+ + + + +Q +Q +ELK +L+E E KS ++ + L EQ +
Sbjct: 1767 NLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
Query: 1353 -EEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQDAEEHV 1408
+E++A + R K +V +A Q ++ ++A K+L ++L++AEE
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
Query: 1409 EAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454
+ NA ++++LQ E+ED + N ++L K R D
Sbjct: 1887 QRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 118 bits (296), Expect = 5e-26
Identities = 125/587 (21%), Positives = 256/587 (43%), Gaps = 67/587 (11%)
Query: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMI 1434
WR + + + EE + L E A + +E + +L E L
Sbjct: 828 WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887
Query: 1435 DVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEE 1494
++ CA + EE A L A ++E + +L + EE
Sbjct: 888 QLQAETELCA------------------EAEELRARLTAKKQELEEICHDL---EARVEE 926
Query: 1495 SLDQLETLKRENKNLQQEISDLTEQIAE--GGKRIHELEKIKKQVEQEKSELQAALEEAE 1552
++ + L+ E K +QQ I +L EQ+ E ++ +LEK+ + + +K LEE +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK------LEEEQ 980
Query: 1553 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE---IDQMKRNHIRIVESMQSTLDAEI 1609
LE + K+ + + L +E + E++E+ + ++K H ++ ++ L E
Sbjct: 981 IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040
Query: 1610 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE 1669
+ R + + ++K+EGD ++ Q+ AE Q K+ +L AL E
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL-----KMQLAKKEEELQA--ALARVE 1093
Query: 1670 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729
+ Q M ++ L+++I EL+ LE SR AE++ D E ++ L T+ ++
Sbjct: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153
Query: 1730 T---------KKKLETDISQIQGEMEDIIQEARNAE--EKAKKAITDAAMMAEELKKEQD 1778
+ K++ E +I + E E EA+ E +K +A+ + +AE+L++ +
Sbjct: 1154 STAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE---LAEQLEQTKR 1210
Query: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG---GKKQIQKLEARVRELEGEVESEQK 1835
A+LE+ K+ LE +L + + ++ L+G + + +K+EA+++EL+ + ++
Sbjct: 1211 VKANLEKAKQTLENERGELANEV----KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER 1266
Query: 1836 RNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNV 1895
E + K + ++ +T + +L L+++++ + +E Q
Sbjct: 1267 VRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLS 1326
Query: 1896 NLSKFRRIQHE-------LEEAEERADIAESQVNKLRVKSREVHTKI 1935
+K ++++ E LEE EE E Q+ L + ++ K+
Sbjct: 1327 LSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 1400 bits (3624), Expect = 0.0
Identities = 762/1917 (39%), Positives = 1187/1917 (61%), Gaps = 26/1917 (1%)
Query: 27 AQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKY 85
A + AK V++ + F A+++ G +V + E G V D + MNPPK+
Sbjct: 25 ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
Query: 86 DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRG 145
K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ ++ YRG
Sbjct: 85 SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + +
Sbjct: 145 KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
Query: 206 KKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
+K+ + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+
Sbjct: 205 RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
Query: 266 IETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPS 325
IETYLLEKSR Q K ER++HIFYQ++S L LL+ +Y F+S G I +P
Sbjct: 261 IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319
Query: 326 IDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 385
D++ T A+ I+GF+ +E +S+ K+ +V+ +GN+ FK+++ +QA VA
Sbjct: 320 QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
Query: 386 KAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTR 445
K +L +N + +A+ PR+KVG +YV K QT +Q AV ALAKA Y+++F W+V R
Sbjct: 380 KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
Query: 446 INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
IN+ LD TK+ FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 440 INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
Query: 505 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561
++EGIEW FIDFG+DL CI+LIE+P G+ ++L+EEC FPKATD +F KL ++ G
Sbjct: 500 QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-G 558
Query: 562 KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621
+ FQKP+ K K A F +IHYAG VDY WL KN DPLN+ V L +S+ + +A
Sbjct: 559 SHSKFQKPRQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
Query: 622 LLF------VG---ATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPH 672
L+ VG TG A G K K F+TV L++E+L KLM LR+T+P+
Sbjct: 617 ELWKDVDRIVGLDQVTGMTETAFGSAY--KTKKGMFRTVGQLYKESLTKLMATLRNTNPN 674
Query: 673 FVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS 732
FVRCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L +
Sbjct: 675 FVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN 734
Query: 733 AIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRT 792
AIP+G F+D K+A E+++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I
Sbjct: 735 AIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF 793
Query: 793 QAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKE 852
QA+CRG+LAR + K ++ ++ +Q N A++ ++HW W +++ K+KPLL+ E+E
Sbjct: 794 QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE 853
Query: 853 MANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL 912
+ EE K KE+ K E + +E+E K L++EKN L Q+QAE + A+AEE +L
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL 913
Query: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
K +LE + ++ R E+EEE N L +K+K++ +L++ +D+ E K++ EK
Sbjct: 914 AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK 973
Query: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
E K+K + EE+ L++ +K KEKK +++ + L EE+K L K + K E
Sbjct: 974 VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE 1033
Query: 1033 QQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMS 1092
+ DLE L++E+K R +LE+AKRKL+G+ Q+ +++ +L +L KKE E+
Sbjct: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
Query: 1093 GLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152
G ++ +DE K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE +
Sbjct: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
Query: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID 1212
LE+ T+AQ E+ KRE E ++++ LEE T HEA +R++HA ++ EL EQ++
Sbjct: 1154 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213
Query: 1213 NLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQR 1272
+R K LEK K ++ + +LA ++ + + K E + L+ Q+ E+ K E R
Sbjct: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR 1273
Query: 1273 LINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSA 1332
L +L + ++LQ E S L+E + + ++ + Q+++ + L+EE + K
Sbjct: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN 1333
Query: 1333 LAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE 1392
L+ ++ + + L+EQ EEE+EA+ L++ + S++A + K + D + E LEE
Sbjct: 1334 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEE 1392
Query: 1393 AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRN 1452
AKKKL + + + +E LEKTK RLQ E++DL +D++ + L+KKQ+
Sbjct: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
Query: 1453 FDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQE 1512
FD++LAE K E + ++ E+R T+ + A EE+L+ E +R+NK L+ +
Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRAD 1512
Query: 1513 ISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQV 1572
+ DL + GK +HELEK K+ +EQ+ E++ LEE E L+ E LR+++ + +
Sbjct: 1513 MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAM 1572
Query: 1573 KSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1632
K++ +R + +DE+ ++ KR I+ V +++ L+ E + R A+ KKKME DL ++E Q
Sbjct: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
Query: 1633 LNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1692
+ AN+ E ++ R QA +KD Q L++A S++++ Q E++ L+AEI +L
Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL 1692
Query: 1693 RATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEA 1752
+ L +ER+R+ AEQE + ++ + + ++L++ K++LE I+Q++ E+E+
Sbjct: 1693 QEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNM 1752
Query: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1812
++ +K + EL E+ + + ++ LE+ K+L+ +L E E
Sbjct: 1753 ELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 1812
Query: 1813 KKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLV 1872
K I LEA++ +LE ++E E K A K +R+ E+K+KE+ Q E++R++ + ++ +
Sbjct: 1813 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872
Query: 1873 DKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
+K A++K KRQ EEAEE++ + R++Q EL++A E + +V+ L+ + R
Sbjct: 1873 EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
Score = 252 bits (643), Expect = 3e-66
Identities = 256/1121 (22%), Positives = 511/1121 (45%), Gaps = 149/1121 (13%)
Query: 718 LYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLL 777
L A ++ KV EG+ + ++ ++LL +I Q + T++F +A
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ-AETELFAEA------ 906
Query: 778 EEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLY 837
EEMR +LA + + +RVE + E R I N K K+
Sbjct: 907 EEMR-ARLAAKKQELEEILHDLESRVEEE---EERNQIL---------QNEKK----KMQ 949
Query: 838 FKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTL-------MQEKND 890
I+ L + + E+E A K + EK EAK K++EE+++ L ++EK
Sbjct: 950 AHIQDLEEQLD-EEEGARQKLQLEKVT-----AEAKIKKMEEEILLLEDQNSKFIKEKKL 1003
Query: 891 LQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE-- 948
++ ++ + LA+ EE+ L K + + E I ++ ER + EE+ EL KRKL+
Sbjct: 1004 MEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGE 1063
Query: 949 -----DECSELKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGL 989
D+ +EL+ ID+L+L LAK E+E K+ V+ L ++A L
Sbjct: 1064 TTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAEL 1123
Query: 990 DETIAK--------------LTKEKKALQEAHQQTLDDLQAEED----KVNTLTKAKIKL 1031
E L++E +AL+ + TLD A+++ + + + K L
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 1032 EQQ------------------VDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDI 1073
E++ +++L LEQ K+ + +LE+ K+ LE D K +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 1074 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASR 1133
+ K + + K KK + ++ L +K+ + L ++L +K +LQ ++ + +E
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 1134 AKAEKQRSDLSRELEEISERLEEAGGAT---SAQIEMNKKREAEFQKMRRDLEEATLQHE 1190
K K + L +L++ E L+E S++I ++ + Q+ + + EEA E
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
Query: 1191 ATAATLRKKHADSVAELGEQ---IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKG 1247
L+ + AD+ ++ + I++L+ K+KL K+ + +++ A + + K K
Sbjct: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
Query: 1248 NLEKMCRALE---DQLSEIKTKEEEQQRLINDLTAQR----ARLQTESGEYSRQLDEKDT 1300
L++ L D ++ + E++Q+ + L A+ AR E + EK+T
Sbjct: 1424 RLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483
Query: 1301 LVSQLSRG-------KQAFTQQIEELKRQLEEEIKAKSALA---HALQSSRH----DCDL 1346
L+R K+ F +Q ++L+ +E+ + +K + H L+ S+ +
Sbjct: 1484 KALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1543
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
+R Q EE ++ + A + + + ++E D R E+ EE K+ L +++++ E
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEA 1603
Query: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
+E + A +K++++ +++DL +E N A + K+ R + +++++ EE
Sbjct: 1604 ELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663
Query: 1467 THA---ELEASQKES----RSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1519
A E+ A KES +SL E+ +++ ++L + +R ++ +QE +L ++
Sbjct: 1664 ARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQERDELADE 1716
Query: 1520 IAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--D 1577
I L K+++E ++L+ LEE ++++E + + L+++ + +E+ +
Sbjct: 1717 ITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAE 1776
Query: 1578 RKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK-----MEGDLNEMEIQ 1632
R A+K + Q +E L A+++ A++ K K +E + ++E Q
Sbjct: 1777 RSAAQKSDNARQQ-------LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
Query: 1633 LNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1692
L + A A + R T+ LK+ + ++D R + KEQ+ R L+ ++EE
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 1693 RATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733
+ SR+ ++EL DA+E + L + ++L N ++
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Score = 190 bits (483), Expect = 1e-47
Identities = 188/843 (22%), Positives = 384/843 (45%), Gaps = 67/843 (7%)
Query: 1111 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS---ERLEEAGGATSAQIEM 1167
K+K L ++ EEE++A+ K +++++ + ELEE+ ++L E + Q++
Sbjct: 840 KVKPL-LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA 898
Query: 1168 NKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSE 1227
+ AE ++MR A A +++ + + +L +++ + Q L+ EK +
Sbjct: 899 ETELFAEAEEMR-----------ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKK 947
Query: 1228 MKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI-----NDLTAQRA 1282
M+ I DL ++ A+ L+ LE +E K K+ E++ L+ + ++
Sbjct: 948 MQAHIQDLEEQLDEEEGARQKLQ-----LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
Query: 1283 RLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRH 1342
++ E S QL E++ L++ + I +L+ +L++E K + L A +
Sbjct: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062
Query: 1343 DCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1402
+ L++Q E Q EL+ ++K E+ + + + + + L+ ++ AQ +
Sbjct: 1063 ETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ-IA 1121
Query: 1403 DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462
+ +E E+ A EK K+ L E+E L ++E T AA + + ++ +AE K+
Sbjct: 1122 ELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKK 1181
Query: 1463 KCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1522
EE EA ++ R + A EE +QLE KR NL++ L E
Sbjct: 1182 ALEEETKNHEAQIQDMRQ------RHATALEELSEQLEQAKRFKANLEKNKQGLETDNKE 1235
Query: 1523 GGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQL--ELNQVKSEVDRKI 1580
+ L+++K + E ++ +L A ++E A + EG LR++L + +++++E+D +
Sbjct: 1236 LACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRVELAEKASKLQNELDN-V 1292
Query: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
+ EE ++ + S++S L + R K + + ++E + N
Sbjct: 1293 STLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQ 1352
Query: 1641 AEALRNYRNT-------QAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELR 1693
E +N Q+ L DT+ +DD L + E L+E + + A L +EE
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKA 1412
Query: 1694 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEAR 1753
++ E+++ +QEL D + + ++L +KK + +++ + +E
Sbjct: 1413 LAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD 1472
Query: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
AE +A++ T A +A L++ + ER K L ++DL D+
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVG-------- 1524
Query: 1814 KQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVD 1873
K + +LE R LE +VE E + +E + E Q ED K LRL+ +
Sbjct: 1525 KNVHELEKSKRALEQQVE-EMRTQLEEL-----------EDELQATEDAK--LRLEVNMQ 1570
Query: 1874 KLQAKV-KSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVH 1932
++A+ + + + E+ EE+ + + + R ++ ELE+ ++ +A + K+ + +++
Sbjct: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630
Query: 1933 TKI 1935
+I
Sbjct: 1631 AQI 1633
Score = 172 bits (437), Expect = 2e-42
Identities = 152/724 (20%), Positives = 344/724 (47%), Gaps = 33/724 (4%)
Query: 854 ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLI 913
A + + +K ++ + AK E + V L ++ + LQ ++ + L +AE++ +
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 914 KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973
K LE+++++ E ++E L+++ R+LE+E + L++ ++ E +EK+
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDDLQAEEDKVNTLTKAKIK 1030
A ++++ + +++ TI L + KK L EA Q L++ DK L K K +
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK---LEKTKNR 1424
Query: 1031 LEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIE--NDKQQLDEKLKKKE 1088
L+Q++DDL L+ ++++ +LE+ ++K D LA+E ++ ++ + + + ++KE
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISARYAEERDRAEAEAREKE 1482
Query: 1089 FEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
+ L +E+ + +++ K+L+A +E+L + + + EK + L +++E
Sbjct: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE 1542
Query: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEEATLQHEATAATLRKKHADSV 1204
E+ +LEE A + + E Q M+ RDL+ Q+E L K+ V
Sbjct: 1543 EMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ----V 1598
Query: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
EL ++++ ++ + K +M++++ DL + +E +KA+ + K R L+ Q+ + +
Sbjct: 1599 RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQ 1658
Query: 1265 TKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLE 1324
+ EE + +++ AQ + + ++ + ++ R ++ Q+ +EL ++
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIT 1718
Query: 1325 EEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY--ETD 1382
KSAL + L E+ EEEQ L K +V + E
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 1383 AIQRTE----ELEEAKKKLAQRLQDAEEHVEA-----VNAKCASLEKTKQRLQNEVEDLM 1433
A Q+++ +LE K+L +LQ+ E V++ ++A A + + +++L+ E ++
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 1434 ID---VERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKN 1490
V RT + + + + ++K++ E+ +A ++ +++ E +
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANA 1898
Query: 1491 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK-RIHELEKIKKQVEQEKSELQAALE 1549
+ + +L+ N+ L +E+S L ++ GG ++Q+ E + L+ + +
Sbjct: 1899 SRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDD 1958
Query: 1550 EAEA 1553
+ E+
Sbjct: 1959 DTES 1962
Score = 39.3 bits (90), Expect = 0.038
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 19/130 (14%)
Query: 1814 KQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVD 1873
+Q ++L+A+ EL E + K E + RKH++ ++E KNIL +
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEE---------KNIL-----AE 894
Query: 1874 KLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELE----EAEERADIAESQVNKLRVKSR 1929
+LQA+ + + +AEE + + I H+LE E EER I +++ K++ +
Sbjct: 895 QLQAETELFA-EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
Query: 1930 EVHTKIISEE 1939
++ ++ EE
Sbjct: 954 DLEEQLDEEE 963
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 1301 bits (3367), Expect = 0.0
Identities = 719/1909 (37%), Positives = 1155/1909 (60%), Gaps = 27/1909 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90
A+ V+V F A + R+ G+ A+ E +G + + DQ+ MNPPK+ K ED
Sbjct: 52 ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
Query: 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150
MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E
Sbjct: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
Query: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210
PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229
Query: 211 TSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 230 VPGE----LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 285
Query: 271 LEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQE 330
LEKSR Q K E S+HIFYQ++ L LL+ + Y F++ G + P ++E
Sbjct: 286 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 343
Query: 331 ELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYL 390
T ++ +LGF+ +E +S+ ++ AV+ +GN+ K+++ +QA A K L
Sbjct: 344 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 403
Query: 391 QNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQL 450
L D +AL PR+KVG +YV K QT +Q A+ ALAKA Y+++F W+V R+N+ L
Sbjct: 404 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 463
Query: 451 DTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
D + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 464 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 522
Query: 509 IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
I WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G
Sbjct: 523 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 581
Query: 566 FQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLFV 625
FQ+P+ + +A FS++HYAG VDY WL KN DPLN+ V L +S + A ++
Sbjct: 582 FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 639
Query: 626 ---GATGAE--AEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680
G G E + G G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN
Sbjct: 640 DVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPN 699
Query: 681 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740
K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+
Sbjct: 700 HEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FM 758
Query: 741 DSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFL 800
D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+L
Sbjct: 759 DGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYL 818
Query: 801 ARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860
AR +QK +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ + +E
Sbjct: 819 ARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQEL 878
Query: 861 EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLE 920
+K +E ++ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K +LE
Sbjct: 879 QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE 938
Query: 921 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980
+ E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K
Sbjct: 939 LVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMK 998
Query: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1040
E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E
Sbjct: 999 KFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMED 1058
Query: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100
L +E+K R +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ ++ ED
Sbjct: 1059 RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED 1118
Query: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
E QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +
Sbjct: 1119 EGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS 1178
Query: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K
Sbjct: 1179 TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGA 1238
Query: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R + +
Sbjct: 1239 WEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEK 1298
Query: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340
R Q E S L+E ++ +LS+ + Q+ + + L+EE +AK AL +++
Sbjct: 1299 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAM 1358
Query: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
+ LREQ EEE A+ R + A +++++WR + E +A E EEA+++ A+
Sbjct: 1359 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAARE 1417
Query: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460
+ + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LAE
Sbjct: 1418 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477
Query: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520
K E E ++ E R + A EE + E L+R+N+ L+ E+ L
Sbjct: 1478 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSK 1537
Query: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
+ GK +HELE+ + EQ ++L+A + E E L E LR+++ + +K++ +R +
Sbjct: 1538 DDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDL 1597
Query: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
+DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A +
Sbjct: 1598 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGK 1657
Query: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700
EA++ R QA +K+ +++ S+E++ Q E+R L+AE+ L+ L ++
Sbjct: 1658 EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASD 1717
Query: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760
R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ +
Sbjct: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYR 1777
Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
K + + EL E+ SA E ++ LE+ +++L+ RL E + A K I LE
Sbjct: 1778 KLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALE 1837
Query: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880
+++ + E ++E E + + + K +R+ E+++KE+ Q EE+R+ +L+D ++K +VK
Sbjct: 1838 SKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVK 1897
Query: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
KRQ EEAEE+++ + RR+Q ELE+ E A+ +V LR + R
Sbjct: 1898 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946
Score = 227 bits (579), Expect = 7e-59
Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%)
Query: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097
Query: 891 LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 1158 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214
Query: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
++ H Q L +L + ++ K ++ LE +V +L L + R + E+ +R+L
Sbjct: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274
Query: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
E L+ Q D E + + EKL++ + E+ + + + ++ ++L K++ +A++
Sbjct: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334
Query: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394
Query: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
R EE EA R++ A L +++ +LE+ + ++ E+DD ++
Sbjct: 1395 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453
Query: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295
E + LEK R + L+E K EE++R + + AR + +R L
Sbjct: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1509
Query: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355
+E+ +L R +A ++E L ++ K+ L A + + + LR Q E +
Sbjct: 1510 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1569
Query: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415
+ + A + V +T++E D R E EE +++LA++L+DAE + +
Sbjct: 1570 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1629
Query: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475
+++L+ E+E+L + K+ R + E ++ EET E
Sbjct: 1630 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1689
Query: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
++R L ++ ++L R + QQ+ ++ +++A G + + K+
Sbjct: 1690 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1749
Query: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593
Q+E +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1750 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1809
Query: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653
I+ + DA R+R+ +E L + E QL R + + R +
Sbjct: 1810 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1867
Query: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713
LK+ L +++ R + L++QL R L+ ++EE + + R+ ++EL D
Sbjct: 1868 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1927
Query: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762
+E + ++ + T+L N ++ + ++E ++E+A++A
Sbjct: 1928 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976
Score = 172 bits (437), Expect = 2e-42
Identities = 181/889 (20%), Positives = 387/889 (43%), Gaps = 99/889 (11%)
Query: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
+++ Q L Q +++ ELQ R+ +LEEE RA A+ + ++L E EE RL
Sbjct: 877 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 932
Query: 1157 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1216
+ + R E ++ R ++ T +K+ + EL ++ +
Sbjct: 933 RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 981
Query: 1217 VKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
+QKL+ EK + ++ ++ + L K + LED+L+E ++ E++ +
Sbjct: 982 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1041
Query: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
L R + + + +L +++ +L + K+ + EL+ Q+ E+ + L
Sbjct: 1042 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1101
Query: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396
L + + E+E A+A+L +++ +A + +A+ + E++ + RT+ E+ ++
Sbjct: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1160
Query: 1397 LAQRLQ----DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER-TNAACAALDKKQR 1451
L + L+ + E+ +++ NA+ ++ + + + EV +L +E T AA+ + ++
Sbjct: 1161 LGEELEALRGELEDTLDSTNAQ----QELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1216
Query: 1452 NFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511
+ L E ++ E+ A +K +L E+ +++ L L+T ++E + ++
Sbjct: 1217 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRR 1272
Query: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571
L Q+ E R + E+ + + ++ QA LE +L E K +R+ EL+
Sbjct: 1273 R---LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSS 1329
Query: 1572 VKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1631
++++ Q L E R++ + ME + +
Sbjct: 1330 TEAQL----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLRE 1367
Query: 1632 QLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1691
QL A R + QA L + + ++ + E +E R A L + E
Sbjct: 1368 QLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1427
Query: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII-- 1749
T+++ ER R+ +QEL DA+ ++ Q L++T +K + Q+ E + +
Sbjct: 1428 KTETVDRLERGRRRLQQELDDATMDLE----QQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483
Query: 1750 --QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE-- 1805
+E AE + ++ A + L++EQ+ LER + L ++ L D+
Sbjct: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543
Query: 1806 ----QLALKGGKKQIQKLEARVRELEGEV---ESEQKRNVEAVKGLR-KHER-------- 1849
+ A + ++ L A+V ELE E+ E + R V+ L+ +HER
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603
Query: 1850 ----------KVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQ 1892
++++ + +E+RK +L+ +++L+A++ S + EEA +Q
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663
Query: 1893 SNVNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939
++ + + E+EE + ++++ ++ R+K E + EE
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712
Score = 154 bits (390), Expect = 6e-37
Identities = 167/769 (21%), Positives = 326/769 (42%), Gaps = 60/769 (7%)
Query: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQ----IDNLQRVKQKLEKEKSEMKMEIDDL 1235
+ L + T Q E A R + V EL +Q + LQ +LE+E++ + ++
Sbjct: 859 KPLLQVTRQDEVLQA--RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAE 916
Query: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295
A + +G L + LE +SE++ + E++ + ++ RLQ E L
Sbjct: 917 AELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHL 976
Query: 1296 DEKDTLVSQLSRGK---QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYE 1352
+ ++ +L K +A ++ EE LE++ S L+ + Q
Sbjct: 977 EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAA 1033
Query: 1353 EEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN 1412
EE+E L + K + +A + + R +ELE+ K++L + +E +
Sbjct: 1034 EEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGR-QELEKLKRRLDGESSELQEQMVEQQ 1092
Query: 1413 AKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELE 1472
+ L R + E++ + E A A L K R LAE ++ E
Sbjct: 1093 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART 1152
Query: 1473 ASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE--L 1530
++K+ R L EL ++ E++LD + +QE+++L + + E RIHE +
Sbjct: 1153 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE-TRIHEAAV 1211
Query: 1531 EKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQM 1590
++++++ Q EL LE+A E L ++ E++++++E+ + E +
Sbjct: 1212 QELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRR 1271
Query: 1591 KRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNT 1650
+R +++ E D E R+R +A ++ + +L + LN A + +T
Sbjct: 1272 RRLELQLQEVQGRAGDGE-RARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330
Query: 1651 QAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL 1710
+A L D Q L QE+ + +LA+ R ++AE LR LE+ +R+ A +EL
Sbjct: 1331 EAQLHDAQELL------QEETRAKLALGSR-VRAMEAEAAGLREQLEEEAAARERAGREL 1383
Query: 1711 LDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMA 1770
T L +++ E + ++ EE ++A +A +
Sbjct: 1384 ----------QTAQAQLSEWRRRQEEEAGALEA-----------GEEARRRAAREAEALT 1422
Query: 1771 EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830
+ L ++ +T LER ++ L+Q + D L++ QL KKQ + + E +
Sbjct: 1423 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482
Query: 1831 ESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAE 1890
+ ++R +G R+ E + LT EE+ Q+ ++L+ + ++ + + E
Sbjct: 1483 RAVEERERAEAEG-REREARALSLTRALEEE-------QEAREELERQNRALRAELEAL- 1533
Query: 1891 EQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
LS + + E E +AE N LR + E+ ++ + E
Sbjct: 1534 ------LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAE 1576
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 1301 bits (3366), Expect = 0.0
Identities = 719/1913 (37%), Positives = 1155/1913 (60%), Gaps = 27/1913 (1%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90
A+ V+V F A + R+ G+ A+ E +G + + DQ+ MNPPK+ K ED
Sbjct: 52 ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
Query: 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150
MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E
Sbjct: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
Query: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210
PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229
Query: 211 TSGKMQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+I
Sbjct: 230 VPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 289
Query: 267 ETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
ETYLLEKSR Q K E S+HIFYQ++ L LL+ + Y F++ G + P
Sbjct: 290 ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG- 347
Query: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
++E T ++ +LGF+ +E +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 348 QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQK 407
Query: 387 AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446
L L D +AL PR+KVG +YV K QT +Q A+ ALAKA Y+++F W+V R+
Sbjct: 408 LCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRL 467
Query: 447 NQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
N+ LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY
Sbjct: 468 NRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 526
Query: 505 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561
++EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G
Sbjct: 527 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-G 585
Query: 562 KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621
FQ+P+ + +A FS++HYAG VDY WL KN DPLN+ V L +S + A
Sbjct: 586 GHPKFQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
Query: 622 LLFV---GATGAE--AEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 676
++ G G E + G G GG+ + F+TV L++E+L++LM L +T+P FVRC
Sbjct: 644 EIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
Query: 677 IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPE 736
I+PN K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+
Sbjct: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
Query: 737 GQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMC 796
G F+D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA
Sbjct: 764 G-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 822
Query: 797 RGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANM 856
RG+LAR +QK +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ +
Sbjct: 823 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 882
Query: 857 KEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTK 916
+E +K +E ++ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K
Sbjct: 883 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 942
Query: 917 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
+LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE
Sbjct: 943 QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1002
Query: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1036
K+K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E +
Sbjct: 1003 AKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIA 1062
Query: 1037 DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQS 1096
D+E L +E+K R +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ +
Sbjct: 1063 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
Query: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
+ EDE QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+
Sbjct: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182
Query: 1157 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1216
+T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R
Sbjct: 1183 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242
Query: 1217 VKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
K EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R +
Sbjct: 1243 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1302
Query: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
+ R Q E S L+E ++ +LS+ + Q+ + + L+EE +AK AL
Sbjct: 1303 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
Query: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396
+++ + LREQ EEE A+ R + A +++++WR + E +A E EEA+++
Sbjct: 1363 VRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRR 1421
Query: 1397 LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKI 1456
A+ + + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++
Sbjct: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
Query: 1457 LAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1516
LAE K E E ++ E R + A EE + E L+R+N+ L+ E+ L
Sbjct: 1482 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
Query: 1517 TEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1576
+ GK +HELE+ + EQ ++L+A + E E L E LR+++ + +K++
Sbjct: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
Query: 1577 DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1636
+R + +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A
Sbjct: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
Query: 1637 NRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1696
+ EA++ R QA +K+ +++ S+E++ Q E+R L+AE+ L+ L
Sbjct: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1721
Query: 1697 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAE 1756
++R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ +
Sbjct: 1722 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1781
Query: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1816
++ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A K I
Sbjct: 1782 DRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTI 1841
Query: 1817 QKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQ 1876
LE+++ + E ++E E + + + K +R+ E+++KE+ Q EE+R+ +L+D ++K
Sbjct: 1842 AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGN 1901
Query: 1877 AKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
+VK KRQ EEAEE+++ + RR+Q ELE+ E A+ +V LR + R
Sbjct: 1902 LRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
Score = 227 bits (579), Expect = 7e-59
Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%)
Query: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
Query: 891 LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 1166 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1222
Query: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
++ H Q L +L + ++ K ++ LE +V +L L + R + E+ +R+L
Sbjct: 1223 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1282
Query: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
E L+ Q D E + + EKL++ + E+ + + + ++ ++L K++ +A++
Sbjct: 1283 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1342
Query: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1343 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1402
Query: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
R EE EA R++ A L +++ +LE+ + ++ E+DD ++
Sbjct: 1403 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1461
Query: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295
E + LEK R + L+E K EE++R + + AR + +R L
Sbjct: 1462 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1517
Query: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355
+E+ +L R +A ++E L ++ K+ L A + + + LR Q E +
Sbjct: 1518 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1577
Query: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415
+ + A + V +T++E D R E EE +++LA++L+DAE + +
Sbjct: 1578 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1637
Query: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475
+++L+ E+E+L + K+ R + E ++ EET E
Sbjct: 1638 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1697
Query: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
++R L ++ ++L R + QQ+ ++ +++A G + + K+
Sbjct: 1698 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1757
Query: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593
Q+E +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1758 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1817
Query: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653
I+ + DA R+R+ +E L + E QL R + + R +
Sbjct: 1818 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1875
Query: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713
LK+ L +++ R + L++QL R L+ ++EE + + R+ ++EL D
Sbjct: 1876 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1935
Query: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762
+E + ++ + T+L N ++ + ++E ++E+A++A
Sbjct: 1936 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
Score = 172 bits (437), Expect = 2e-42
Identities = 181/889 (20%), Positives = 387/889 (43%), Gaps = 99/889 (11%)
Query: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
+++ Q L Q +++ ELQ R+ +LEEE RA A+ + ++L E EE RL
Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 940
Query: 1157 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1216
+ + R E ++ R ++ T +K+ + EL ++ +
Sbjct: 941 RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 989
Query: 1217 VKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
+QKL+ EK + ++ ++ + L K + LED+L+E ++ E++ +
Sbjct: 990 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1049
Query: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
L R + + + +L +++ +L + K+ + EL+ Q+ E+ + L
Sbjct: 1050 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1109
Query: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396
L + + E+E A+A+L +++ +A + +A+ + E++ + RT+ E+ ++
Sbjct: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1168
Query: 1397 LAQRLQ----DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER-TNAACAALDKKQR 1451
L + L+ + E+ +++ NA+ ++ + + + EV +L +E T AA+ + ++
Sbjct: 1169 LGEELEALRGELEDTLDSTNAQ----QELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1224
Query: 1452 NFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511
+ L E ++ E+ A +K +L E+ +++ L L+T ++E + ++
Sbjct: 1225 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRR 1280
Query: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571
L Q+ E R + E+ + + ++ QA LE +L E K +R+ EL+
Sbjct: 1281 R---LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSS 1337
Query: 1572 VKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1631
++++ Q L E R++ + ME + +
Sbjct: 1338 TEAQL----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLRE 1375
Query: 1632 QLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1691
QL A R + QA L + + ++ + E +E R A L + E
Sbjct: 1376 QLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1435
Query: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII-- 1749
T+++ ER R+ +QEL DA+ ++ Q L++T +K + Q+ E + +
Sbjct: 1436 KTETVDRLERGRRRLQQELDDATMDLE----QQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1491
Query: 1750 --QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE-- 1805
+E AE + ++ A + L++EQ+ LER + L ++ L D+
Sbjct: 1492 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1551
Query: 1806 ----QLALKGGKKQIQKLEARVRELEGEV---ESEQKRNVEAVKGLR-KHER-------- 1849
+ A + ++ L A+V ELE E+ E + R V+ L+ +HER
Sbjct: 1552 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1611
Query: 1850 ----------KVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQ 1892
++++ + +E+RK +L+ +++L+A++ S + EEA +Q
Sbjct: 1612 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1671
Query: 1893 SNVNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939
++ + + E+EE + ++++ ++ R+K E + EE
Sbjct: 1672 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
Score = 154 bits (390), Expect = 6e-37
Identities = 167/769 (21%), Positives = 326/769 (42%), Gaps = 60/769 (7%)
Query: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQ----IDNLQRVKQKLEKEKSEMKMEIDDL 1235
+ L + T Q E A R + V EL +Q + LQ +LE+E++ + ++
Sbjct: 867 KPLLQVTRQDEVLQA--RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAE 924
Query: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295
A + +G L + LE +SE++ + E++ + ++ RLQ E L
Sbjct: 925 AELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHL 984
Query: 1296 DEKDTLVSQLSRGK---QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYE 1352
+ ++ +L K +A ++ EE LE++ S L+ + Q
Sbjct: 985 EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAA 1041
Query: 1353 EEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN 1412
EE+E L + K + +A + + R +ELE+ K++L + +E +
Sbjct: 1042 EEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGR-QELEKLKRRLDGESSELQEQMVEQQ 1100
Query: 1413 AKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELE 1472
+ L R + E++ + E A A L K R LAE ++ E
Sbjct: 1101 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART 1160
Query: 1473 ASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE--L 1530
++K+ R L EL ++ E++LD + +QE+++L + + E RIHE +
Sbjct: 1161 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE-TRIHEAAV 1219
Query: 1531 EKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQM 1590
++++++ Q EL LE+A E L ++ E++++++E+ + E +
Sbjct: 1220 QELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRR 1279
Query: 1591 KRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNT 1650
+R +++ E D E R+R +A ++ + +L + LN A + +T
Sbjct: 1280 RRLELQLQEVQGRAGDGE-RARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338
Query: 1651 QAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL 1710
+A L D Q L QE+ + +LA+ R ++AE LR LE+ +R+ A +EL
Sbjct: 1339 EAQLHDAQELL------QEETRAKLALGSR-VRAMEAEAAGLREQLEEEAAARERAGREL 1391
Query: 1711 LDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMA 1770
T L +++ E + ++ EE ++A +A +
Sbjct: 1392 ----------QTAQAQLSEWRRRQEEEAGALEA-----------GEEARRRAAREAEALT 1430
Query: 1771 EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830
+ L ++ +T LER ++ L+Q + D L++ QL KKQ + + E +
Sbjct: 1431 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
Query: 1831 ESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAE 1890
+ ++R +G R+ E + LT EE+ Q+ ++L+ + ++ + + E
Sbjct: 1491 RAVEERERAEAEG-REREARALSLTRALEEE-------QEAREELERQNRALRAELEAL- 1541
Query: 1891 EQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
LS + + E E +AE N LR + E+ ++ + E
Sbjct: 1542 ------LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAE 1584
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 1288 bits (3333), Expect = 0.0
Identities = 719/1946 (36%), Positives = 1155/1946 (59%), Gaps = 60/1946 (3%)
Query: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90
A+ V+V F A + R+ G+ A+ E +G + + DQ+ MNPPK+ K ED
Sbjct: 52 ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
Query: 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150
MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E
Sbjct: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
Query: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210
PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229
Query: 211 TSGKMQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+I
Sbjct: 230 VPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 289
Query: 267 ETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
ETYLLEKSR Q K E S+HIFYQ++ L LL+ + Y F++ G + P
Sbjct: 290 ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG- 347
Query: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
++E T ++ +LGF+ +E +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 348 QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQK 407
Query: 387 AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446
L L D +AL PR+KVG +YV K QT +Q A+ ALAKA Y+++F W+V R+
Sbjct: 408 LCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRL 467
Query: 447 NQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
N+ LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY
Sbjct: 468 NRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 526
Query: 505 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561
++EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G
Sbjct: 527 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-G 585
Query: 562 KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621
FQ+P+ + +A FS++HYAG VDY WL KN DPLN+ V L +S + A
Sbjct: 586 GHPKFQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
Query: 622 LLFV------------------------------------GATGAE--AEAGGGKKGGKK 643
++ G G E + G G GG+
Sbjct: 644 EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
Query: 644 KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVL 703
+ F+TV L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVL
Sbjct: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
Query: 704 EGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFG 763
EGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G
Sbjct: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVG 822
Query: 764 HTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVR 823
+K+FF+AG+L LEE RD K+ +I QA RG+LAR +QK +++ ++ +Q N
Sbjct: 823 QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
Query: 824 AFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVT 883
A++ ++HW W +L+ K+KPLL+ ++ + +E +K +E ++ + EL+ ++
Sbjct: 883 AYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQ 942
Query: 884 LMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L +E+ L Q++AEA+ A+AEE +L K +LE + E+ R +EEE + ++ +
Sbjct: 943 LEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTE 1002
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
K++L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L
Sbjct: 1003 KKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1062
Query: 1004 QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1063
++ + EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1063 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1122
Query: 1064 KLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 1123
QE ++ + ++L +L +KE E+ ++ EDE QL K ++E QA + E +
Sbjct: 1123 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1182
Query: 1124 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183
E++E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LE
Sbjct: 1183 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1242
Query: 1184 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 1243
E T HEA LR++H ++ EL EQ++ +R K EK + ++ E+ +L + + ++
Sbjct: 1243 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQ 1302
Query: 1244 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVS 1303
A+ E+ R LE QL E++ + + +R + + R Q E S L+E ++
Sbjct: 1303 TARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTI 1362
Query: 1304 QLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363
+LS+ + Q+ + + L+EE +AK AL +++ + LREQ EEE A+ R
Sbjct: 1363 RLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGR 1422
Query: 1364 AMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQ 1423
+ A +++++WR + E +A E EEA+++ A+ + + + LE+ ++
Sbjct: 1423 ELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR 1481
Query: 1424 RLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLST 1483
RLQ E++D +D+E+ + L+KKQR FD++LAE K E E ++ E R
Sbjct: 1482 RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA 1541
Query: 1484 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSE 1543
+ A EE + E L+R+N+ L+ E+ L + GK +HELE+ + EQ ++
Sbjct: 1542 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1601
Query: 1544 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQS 1603
L+A + E E L E LR+++ + +K++ +R + +DE ++ +R + + +
Sbjct: 1602 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 1661
Query: 1604 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDD 1663
D E + R A+ +KK+EG+L E++ Q+ A + EA++ R QA +K+ +++
Sbjct: 1662 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE 1721
Query: 1664 ALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1723
S+E++ Q E+R L+AE+ L+ L ++R+R+ A+Q+ + ++ V +
Sbjct: 1722 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1781
Query: 1724 NTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1783
+++ K++LE + Q++ E+E+ + ++ +K + + EL E+ SA
Sbjct: 1782 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA 1841
Query: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843
E ++ LE+ +++L+ RL E + A K I LE+++ + E ++E E + + + K
Sbjct: 1842 ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
Query: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903
+R+ E+++KE+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ + RR+
Sbjct: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
Query: 1904 QHELEEAEERADIAESQVNKLRVKSR 1929
Q ELE+ E A+ +V LR + R
Sbjct: 1962 QRELEDVTESAESMNREVTTLRNRLR 1987
Score = 227 bits (579), Expect = 7e-59
Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%)
Query: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
Query: 891 LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
Query: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
++ H Q L +L + ++ K ++ LE +V +L L + R + E+ +R+L
Sbjct: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
Query: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
E L+ Q D E + + EKL++ + E+ + + + ++ ++L K++ +A++
Sbjct: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
Query: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
Query: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
R EE EA R++ A L +++ +LE+ + ++ E+DD ++
Sbjct: 1436 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1494
Query: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295
E + LEK R + L+E K EE++R + + AR + +R L
Sbjct: 1495 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1550
Query: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355
+E+ +L R +A ++E L ++ K+ L A + + + LR Q E +
Sbjct: 1551 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1610
Query: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415
+ + A + V +T++E D R E EE +++LA++L+DAE + +
Sbjct: 1611 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1670
Query: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475
+++L+ E+E+L + K+ R + E ++ EET E
Sbjct: 1671 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
Query: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
++R L ++ ++L R + QQ+ ++ +++A G + + K+
Sbjct: 1731 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1790
Query: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593
Q+E +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1791 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850
Query: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653
I+ + DA R+R+ +E L + E QL R + + R +
Sbjct: 1851 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1908
Query: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713
LK+ L +++ R + L++QL R L+ ++EE + + R+ ++EL D
Sbjct: 1909 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1968
Query: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762
+E + ++ + T+L N ++ + ++E ++E+A++A
Sbjct: 1969 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017
Score = 172 bits (437), Expect = 2e-42
Identities = 181/889 (20%), Positives = 387/889 (43%), Gaps = 99/889 (11%)
Query: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
+++ Q L Q +++ ELQ R+ +LEEE RA A+ + ++L E EE RL
Sbjct: 918 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 973
Query: 1157 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1216
+ + R E ++ R ++ T +K+ + EL ++ +
Sbjct: 974 RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 1022
Query: 1217 VKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
+QKL+ EK + ++ ++ + L K + LED+L+E ++ E++ +
Sbjct: 1023 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1082
Query: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
L R + + + +L +++ +L + K+ + EL+ Q+ E+ + L
Sbjct: 1083 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142
Query: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396
L + + E+E A+A+L +++ +A + +A+ + E++ + RT+ E+ ++
Sbjct: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1201
Query: 1397 LAQRLQ----DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER-TNAACAALDKKQR 1451
L + L+ + E+ +++ NA+ ++ + + + EV +L +E T AA+ + ++
Sbjct: 1202 LGEELEALRGELEDTLDSTNAQ----QELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257
Query: 1452 NFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511
+ L E ++ E+ A +K +L E+ +++ L L+T ++E + ++
Sbjct: 1258 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRR 1313
Query: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571
L Q+ E R + E+ + + ++ QA LE +L E K +R+ EL+
Sbjct: 1314 R---LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSS 1370
Query: 1572 VKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1631
++++ Q L E R++ + ME + +
Sbjct: 1371 TEAQL----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLRE 1408
Query: 1632 QLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1691
QL A R + QA L + + ++ + E +E R A L + E
Sbjct: 1409 QLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468
Query: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII-- 1749
T+++ ER R+ +QEL DA+ ++ Q L++T +K + Q+ E + +
Sbjct: 1469 KTETVDRLERGRRRLQQELDDATMDLE----QQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1524
Query: 1750 --QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE-- 1805
+E AE + ++ A + L++EQ+ LER + L ++ L D+
Sbjct: 1525 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1584
Query: 1806 ----QLALKGGKKQIQKLEARVRELEGEV---ESEQKRNVEAVKGLR-KHER-------- 1849
+ A + ++ L A+V ELE E+ E + R V+ L+ +HER
Sbjct: 1585 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1644
Query: 1850 ----------KVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQ 1892
++++ + +E+RK +L+ +++L+A++ S + EEA +Q
Sbjct: 1645 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1704
Query: 1893 SNVNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939
++ + + E+EE + ++++ ++ R+K E + EE
Sbjct: 1705 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
Score = 154 bits (390), Expect = 6e-37
Identities = 167/769 (21%), Positives = 326/769 (42%), Gaps = 60/769 (7%)
Query: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQ----IDNLQRVKQKLEKEKSEMKMEIDDL 1235
+ L + T Q E A R + V EL +Q + LQ +LE+E++ + ++
Sbjct: 900 KPLLQVTRQDEVLQA--RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAE 957
Query: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295
A + +G L + LE +SE++ + E++ + ++ RLQ E L
Sbjct: 958 AELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHL 1017
Query: 1296 DEKDTLVSQLSRGK---QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYE 1352
+ ++ +L K +A ++ EE LE++ S L+ + Q
Sbjct: 1018 EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAA 1074
Query: 1353 EEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN 1412
EE+E L + K + +A + + R +ELE+ K++L + +E +
Sbjct: 1075 EEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGR-QELEKLKRRLDGESSELQEQMVEQQ 1133
Query: 1413 AKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELE 1472
+ L R + E++ + E A A L K R LAE ++ E
Sbjct: 1134 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART 1193
Query: 1473 ASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE--L 1530
++K+ R L EL ++ E++LD + +QE+++L + + E RIHE +
Sbjct: 1194 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE-TRIHEAAV 1252
Query: 1531 EKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQM 1590
++++++ Q EL LE+A E L ++ E++++++E+ + E +
Sbjct: 1253 QELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRR 1312
Query: 1591 KRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNT 1650
+R +++ E D E R+R +A ++ + +L + LN A + +T
Sbjct: 1313 RRLELQLQEVQGRAGDGE-RARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
Query: 1651 QAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL 1710
+A L D Q L QE+ + +LA+ R ++AE LR LE+ +R+ A +EL
Sbjct: 1372 EAQLHDAQELL------QEETRAKLALGSR-VRAMEAEAAGLREQLEEEAAARERAGREL 1424
Query: 1711 LDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMA 1770
T L +++ E + ++ EE ++A +A +
Sbjct: 1425 ----------QTAQAQLSEWRRRQEEEAGALEA-----------GEEARRRAAREAEALT 1463
Query: 1771 EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830
+ L ++ +T LER ++ L+Q + D L++ QL KKQ + + E +
Sbjct: 1464 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
Query: 1831 ESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAE 1890
+ ++R +G R+ E + LT EE+ Q+ ++L+ + ++ + + E
Sbjct: 1524 RAVEERERAEAEG-REREARALSLTRALEEE-------QEAREELERQNRALRAELEAL- 1574
Query: 1891 EQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
LS + + E E +AE N LR + E+ ++ + E
Sbjct: 1575 ------LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAE 1617
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 595 bits (1535), Expect = e-169
Identities = 439/1439 (30%), Positives = 721/1439 (50%), Gaps = 107/1439 (7%)
Query: 38 VFVVDPKESFVKATVQS--REGGKVTAKTEAGAT---VTVKDDQVFPM-NPPKYDKIEDM 91
V++ DP+E + A + R G KV T +V + + P+ NP D+
Sbjct: 13 VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
Query: 92 AMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150
+++LHEPAVL+NL+ R+A + +IYTYSG+ V +NPYK LP+Y ++ AY G+ +
Sbjct: 73 TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
Query: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210
PHIF++++ AY+ M + NQSI+++GESGAGKTV+ + ++YFAT++ +G
Sbjct: 133 MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189
Query: 211 TSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270
+ED+++++NP+ EA GNAKT RNDNSSRFGK+ I F ++ A++ TYL
Sbjct: 190 --------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYL 241
Query: 271 LEKSRVTFQLKAERSYHIFYQIMSN-KKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQ 329
LEKSRV FQ + ER+YHIFYQ+ ++ ++ + + L + ++Y + G + ++D+
Sbjct: 242 LEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDR 300
Query: 330 EELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
E++ T +LGF D ++ ++K+ A++H GN++ E + +
Sbjct: 301 AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360
Query: 390 LQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQ 449
L L S + + LC ++ +E V K T Q NA ALAK +Y +F ++V RINQ
Sbjct: 361 LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
Query: 450 LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509
L + FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 421 LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480
Query: 510 EWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKP 569
WT IDF D I+LIE MGI +L+EEC+ P TD ++ KLY + ++ F+KP
Sbjct: 481 PWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
Query: 570 KPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF----- 624
+ + F + H+A V+Y G+L+KN+D + + +V + + S A F
Sbjct: 540 RMS----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595
Query: 625 -VGATGAEAEAGGGKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
G+ K+ K F+ TV + FR +L LM L +T PH+VRCI PN+
Sbjct: 596 PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
Query: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 742
K P + + ++ QLR GVLE IRI + +PSR Y +F RY +L E F D
Sbjct: 656 KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713
Query: 743 KKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLAR 802
K+ + +L + D QY+FG TK+FF+AG + LE++R +KL Q Q RG+L R
Sbjct: 714 KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773
Query: 803 VEYQKMVERRESIFCIQY---------NVRAFMNVKHWPWMKLYFKIKP-LLKSAETEKE 852
++ + ERR ++ QY + A + W + + + L++S
Sbjct: 774 KKFLR--ERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIR 831
Query: 853 MANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL 912
MA + T + ++ R+ + +++E + LQ A A LA + +
Sbjct: 832 MATI------TMQAYSRGFLARRRYRK----MLEEHKAVILQKYARA-WLARRRFQSIRR 880
Query: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
IQL +++ + ++ ED+ + N L K L + + I LE L K +
Sbjct: 881 FVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHR 940
Query: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
E K K + ++E +AKL K L+ +Q LQ + +++ K K++
Sbjct: 941 RNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKMD 991
Query: 1033 QQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMS 1092
L +++E++ RM LE K + T D E Q L E++K + E
Sbjct: 992 NLTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEKM 1041
Query: 1093 GLQSKIEDEQALGMQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QRSDLSR 1145
LQ +E E L+ ++ L + I E E+EIE +A + EK Q+ ++
Sbjct: 1042 QLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMRE 1101
Query: 1146 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA 1205
++ EI+++L E S IE + R + DLE E A K A V
Sbjct: 1102 KMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKKATRVL 1151
Query: 1206 ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA---SNMETVSKAKGNLEKMCRALEDQLSE 1262
E + Q K EKE + ++ L+ ++++ + + + ++ + R +L+
Sbjct: 1152 E-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTS 1206
Query: 1263 IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEK-DTLVSQLSRGKQAFTQQIEELKR 1321
+ ++ I++L Q+ L+ E + ++ K + L +QL R ++ Q + L+
Sbjct: 1207 ENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEA 1266
Query: 1322 QLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYET 1381
Q E K K L +Q + D L++Q+E E E K ++ S+ E + E
Sbjct: 1267 QNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEEL 1324
Query: 1382 DAIQRT-EELEEAKKKLAQRLQDAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMIDVE 1437
D R ++L++ K L++ + A + + K L+ ++ +++L++D++
Sbjct: 1325 DMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
Score = 79.0 bits (193), Expect = 4e-14
Identities = 99/525 (18%), Positives = 222/525 (42%), Gaps = 45/525 (8%)
Query: 1313 TQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEV 1372
T +++ L+++LE++ K L L S L E+ Q+ +AEL++A
Sbjct: 888 TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
Query: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCAS-LEKTKQRLQNEVED 1431
A R YE + + +EE KL + + E E + K E+ K+++ N +
Sbjct: 937 ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
Query: 1432 LMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNA 1491
L DV++ L+K ++ K ++ ++++ ++E ++L E ++++
Sbjct: 997 LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
Query: 1492 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEA 1551
E + LK E L +++ K I E EK + ++ +K +++ ++
Sbjct: 1047 VEGEHVTSDGLKAEVARLSKQV-----------KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
Query: 1552 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQST--LDAEI 1609
+ + + +I + LE ++ R E E +++ ++T L++
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
Query: 1610 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE 1669
+S+ D +K++E LN + L+ + R + ++ L
Sbjct: 1156 QSQKDCY--EKEIEA-LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIP 1212
Query: 1670 DLKEQLAMVERRANLLQAEI----EELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1725
D K+Q++ +E++ L+ + E+++ LE+ +++E + ++R + L QN
Sbjct: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNE 1269
Query: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
K+KL I ++Q + + ++ E +A+ + E + ++ +R
Sbjct: 1270 IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329
Query: 1786 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830
+ K L+ VK L + +A + G K+ + RE E ++
Sbjct: 1330 VIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
Score = 43.9 bits (102), Expect = 0.002
Identities = 81/407 (19%), Positives = 174/407 (42%), Gaps = 42/407 (10%)
Query: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589
L+K+++ + ++ L+ + E I++ Q + +A K+
Sbjct: 753 LDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAI 812
Query: 1590 MKRNHIR--IVESM-----QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE 1642
+ + H R +V S+ +T+ + SR R + + + ++ I +A A
Sbjct: 813 IIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLAR 872
Query: 1643 ALRNYRNTQAILKDTQL-----HLDDALRSQEDLKEQLAMVERRANL--LQA----EIEE 1691
R +++ + + + QL L L Q KE +VE+ +L L+A +I++
Sbjct: 873 --RRFQSIRRFVLNIQLTYRVQRLQKKLEDQN--KENHGLVEKLTSLAALRAGDVEKIQK 928
Query: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQE 1751
L A LE+ R+ E++ + V+ + L +LET QIQ ++++ +E
Sbjct: 929 LEAELEKAATHRRNYEEKGKRYRDAVE---EKLAKLQKHNSELETQKEQIQLKLQEKTEE 985
Query: 1752 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ--LAL 1809
+ + K + D +++KE+ LE K+ E +D + ++ ++ AL
Sbjct: 986 LKEKMDNLTKQLFD------DVQKEERQRMLLE---KSFELKTQDYEKQIQSLKEEIKAL 1036
Query: 1810 KGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQ 1869
K K Q+Q L +++E R + VK + + E++++ L Q + K++ Q
Sbjct: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHV---Q 1093
Query: 1870 DLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADI 1916
+++ K+ +Q E+ + +V + R +LE E ++
Sbjct: 1094 SQKREMREKMSEITKQLLESYDIEDV---RSRLSVEDLEHLNEDGEL 1137
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 586 bits (1511), Expect = e-167
Identities = 439/1452 (30%), Positives = 709/1452 (48%), Gaps = 164/1452 (11%)
Query: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKR 148
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFAT---------- 182
Query: 209 EVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
V+ + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 183 -VSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
Query: 269 YLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSID 327
YLLEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG + +D
Sbjct: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
Query: 328 DQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
Query: 388 AYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRIN 447
L ++ ++ LC+ ++ E K + Q NA ALAK +Y K+F W+V +N
Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
Query: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY HL K F+
Sbjct: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 568 KPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF--- 624
KP+ + F + H+A V+Y G+L+KNKD + E + + + S K L LF
Sbjct: 540 KPRLS----NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
Query: 625 --------------VGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTH 670
T A+ G+ G K +TV FR +L+ LM L +T
Sbjct: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHK-KTVGHQFRNSLHLLMETLNATT 654
Query: 671 PHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLN 730
PH+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 655 PHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM 714
Query: 731 ASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLIT 790
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL
Sbjct: 715 KQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACI 771
Query: 791 RTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETE 850
R Q RG+L R +Y +M R++ +Q VR + + Y K K+A
Sbjct: 772 RIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQ-------ARCYAKFLRRTKAATII 821
Query: 851 KEMANMKEEFEKTKEELAKT-------------EAKRKELEEKMVTLMQE---------- 887
++ M + K A T RK L E ++Q+
Sbjct: 822 QKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTH 881
Query: 888 -KNDL-----------QLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 935
K + ++ + E L ++ K I +E KI ++ + +++ +
Sbjct: 882 YKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNK 941
Query: 936 INAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 991
L K LE E +L+ D++ L+L+ E+E +V +L EE+A L +
Sbjct: 942 DYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRK 997
Query: 992 TIAKLTKEKKALQE---AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKI 1048
+ + EKK ++E ++Q + L + + NTL K E+E
Sbjct: 998 DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQ---------------EKEALN 1042
Query: 1049 RMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF--EMSGLQSKIEDEQALGM 1106
+++AK E K E T +E D DE+L+ + E S L+ + +D
Sbjct: 1043 HRIVQQAKEMTETMEKKLVEETKQLELDLN--DERLRYQNLLNEFSRLEERYDD------ 1094
Query: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
K+ L + + + S ++E S E+E+I R EE ++
Sbjct: 1095 --LKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP-SEKKVPLD 1151
Query: 1167 MN-----KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
M+ +KR E ++ ++ +++ + E + K + G +++ +Q+L
Sbjct: 1152 MSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQEL 1211
Query: 1222 EKEKSEMKMEIDDL--ASNMETVSKAKGNLEKMCRALEDQLS----EIKTKEEEQQRLIN 1275
E E ++K E+++L A + ++ + R L +QL+ E+ ++EE L +
Sbjct: 1212 ESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRS 1271
Query: 1276 DLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAH 1335
L +Q+ +Q + D+K+T+ + ++++K + E +A L
Sbjct: 1272 QLVSQKEAIQPK--------DDKNTMTD-----STILLEDVQKMKDK-GEIAQAYIGLKE 1317
Query: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
+SS D L E E + L++A S++ + +E +A E++ K+
Sbjct: 1318 TNRSSALDYHELNEDGELWLVYEG-LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKE 1376
Query: 1396 K-------LAQRLQ-DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALD 1447
+ LAQ LQ E +E ASL+ RL NE DLM +E+ + L
Sbjct: 1377 ENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKLK 1430
Query: 1448 KKQRNFDKILAE 1459
K+ + F K + E
Sbjct: 1431 KQLKVFAKKIGE 1442
Score = 97.4 bits (241), Expect = 1e-19
Identities = 172/787 (21%), Positives = 314/787 (39%), Gaps = 94/787 (11%)
Query: 793 QAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKE 852
Q+ RGFLAR Y+K++ +++ IQ VR ++ H Y + + +
Sbjct: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTH------YKRSMHAIIYLQCCFR 897
Query: 853 MANMKEEFEKTKEELAKTEAKRK---ELEEKMVTLMQEKNDLQLQVQAEADSLADAEERC 909
K E +K K E E +K +E K++ L ++ ++ + + L + E
Sbjct: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIY 957
Query: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
+ + K++ ER + EE T + L++E ++L+KD++ +E
Sbjct: 958 NSETE-------KLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010
Query: 970 KE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAHQQTLD 1012
+ K TE V NL EE L + L T EKK ++E Q L
Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLEL- 1069
Query: 1013 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMD 1072
DL E + L +LE++ DD L++E + + + + K + ES
Sbjct: 1070 DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Query: 1073 IENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAER-- 1130
++ ++++ + E + K+ + +L ++LQK++ EL+ + +++E++ +
Sbjct: 1126 FSSEIAEMEDIPSRTE---EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQ 1182
Query: 1131 --ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188
S+AK E++ ELE S + +E NKK + E ++R+ L
Sbjct: 1183 VLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS----- 1230
Query: 1189 HEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS-KAKG 1247
E +A + A + L EQ L V ++L+ K E+ + L S E + K
Sbjct: 1231 -EKSAPEVTAPGAPAYRVLMEQ---LTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDK 1286
Query: 1248 NLEKMCRALEDQLSEIKTKEEEQQRLI-----NDLTAQRARLQTESGE----YSRQLDEK 1298
N L + + ++K K E Q I N +A E GE Y
Sbjct: 1287 NTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQAN 1346
Query: 1299 DTLVSQLSRGKQAFTQQIEELKRQL----EEEIKAKSALAHALQ---SSRHDCDLLREQY 1351
L SQL K++ + E L+ ++ EE + + LA LQ +R + L E
Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEIT 1406
Query: 1352 EEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
E +L + K + V + + + + A ++ ELE + + Q +E + V
Sbjct: 1407 RLTNE-NLDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDEPIRPV 1464
Query: 1412 NAK------CASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCE 1465
N LE K+ Q V++L+++++ A + + A C
Sbjct: 1465 NIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLI-------PGLPAYILFMCV 1517
Query: 1466 ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK 1525
L QK L++ + IK ++ D ET+ N + + L + E G
Sbjct: 1518 RHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGF 1577
Query: 1526 RIHELEK 1532
H +
Sbjct: 1578 MKHNTSR 1584
Score = 75.1 bits (183), Expect = 6e-13
Identities = 125/567 (22%), Positives = 235/567 (41%), Gaps = 96/567 (16%)
Query: 1084 LKKKEFEMSGLQSK-IEDEQALGMQLQKKIKELQARIEE--------LEEEIEAERASRA 1134
+ K+E + ++++ +E + L + ++ KI +LQ +++E +E+ E +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
Query: 1195 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMC 1253
++HAD + EQ + NL+ L++EK A N V +AK E M
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAKEMTETME 1057
Query: 1254 RALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLS------- 1306
+ L EE ++L DL +R R Q E+SR + D L +++
Sbjct: 1058 KKLV----------EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPK 1107
Query: 1307 -------------RGKQAFTQQIEELK-------RQLEEEIKAKSALAHALQSSRHDCDL 1346
+ F+ +I E++ E+++ +L LQ + +
Sbjct: 1108 PGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQ 1167
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWR-TKYETDAIQRTEELEEAKKKLAQRLQD-- 1403
++ ++E + K E E Q R + E ++++R +ELE KKL L +
Sbjct: 1168 EKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKR-QELESENKKLKNELNELR 1226
Query: 1404 ---AEEHVEAVNAKCA--------SLEKTKQRLQNEVEDLMID----VERTNAACAALDK 1448
+E+ V A A L + L E+++I V + A DK
Sbjct: 1227 KALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDK 1286
Query: 1449 KQRNFDKILAEWKQKCEETH--AELEASQKESRSLSTELFKIKNAYEESLDQLETLKREN 1506
IL E QK ++ A+ KE+ S + N E E LK+ N
Sbjct: 1287 NTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQAN 1346
Query: 1507 KNLQQEISDLTEQIAEGGKRIH-ELEKIKKQVEQEKSELQAALE-----EAEASLEHEEG 1560
+ L+ ++ + + E++ +K++ +++ L L+ EASL+HE
Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEIT 1406
Query: 1561 KILRIQLELNQVKSEVDRKIAEKDEEI 1587
++ L+L + + D+ + + +++
Sbjct: 1407 RLTNENLDLMEQLEKQDKTVRKLKKQL 1433
Score = 59.3 bits (142), Expect = 4e-08
Identities = 86/378 (22%), Positives = 157/378 (41%), Gaps = 75/378 (19%)
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKIKKQVEQEKSELQAALEEAEAS 1554
+E K+ + ++ +I L ++ E K + +L ++ E +L++ LE + S
Sbjct: 915 VERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS 974
Query: 1555 LEHEE---GKILRIQLELNQVKSEVDRKIAEK---DEEIDQMKRNHIRIVESMQSTLDAE 1608
E + G++L +Q E+ +++ ++++ +EK +E D+ K+ ++V ++
Sbjct: 975 EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL------- 1027
Query: 1609 IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLD---DAL 1665
+ + LK++ E LNH A+ + + + + QL LD + L
Sbjct: 1028 ---KEENTLLKQEKEA--------LNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERL 1076
Query: 1666 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1725
R Q L E + ER +L EE+ + + K R H+ N
Sbjct: 1077 RYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPGHK-----------RTDSTHSSNE 1121
Query: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
S E S EMEDI +R E KK D ++ + L++
Sbjct: 1122 S--------EYIFSSEIAEMEDI--PSRTEEPSEKKVPLDMSLFLK-----------LQK 1160
Query: 1786 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE------GEVESEQKRNVE 1839
LEQ + +Q LD E+ L+ K+ ++ + R ELE E+ESE K+
Sbjct: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN 1220
Query: 1840 AVKGLRK--HERKVKELT 1855
+ LRK E+ E+T
Sbjct: 1221 ELNELRKALSEKSAPEVT 1238
Score = 52.4 bits (124), Expect = 4e-06
Identities = 72/338 (21%), Positives = 132/338 (39%), Gaps = 36/338 (10%)
Query: 1605 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDA 1664
L E RS +L ME + +++ +++ N+ + N + I L
Sbjct: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967
Query: 1665 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLL 1720
L + +E+ + R LQ EI +LR LEQT +K E+ + + V L
Sbjct: 968 LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027
Query: 1721 HTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1780
+NT L K+ L I Q EM + ++ KK + + + +L E+
Sbjct: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078
Query: 1781 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ------------IQKLEARVRELEG 1828
+L LE+ DL+ + + G K+ A + ++
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138
Query: 1829 EVESEQKRNVEAVKGL-RKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1887
E ++ V L K +++V EL E K ++ QD +D+ + +V K + E
Sbjct: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKEE 1191
Query: 1888 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLR 1925
E + L + ELE ++ ++++N+LR
Sbjct: 1192 ERPQIRGAELEYESLKRQELESENKKL---KNELNELR 1226
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 584 bits (1506), Expect = e-166
Identities = 435/1445 (30%), Positives = 702/1445 (48%), Gaps = 177/1445 (12%)
Query: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKR 148
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFAT---------- 182
Query: 209 EVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
V+ + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 183 -VSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
Query: 269 YLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSID 327
YLLEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG + +D
Sbjct: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
Query: 328 DQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
Query: 388 AYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRIN 447
L ++ ++ LC+ ++ E K + Q NA ALAK +Y K+F W+V +N
Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
Query: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY HL K F+
Sbjct: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 568 KPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF--- 624
KP+ + F + H+A V+Y G+L+KNKD + E + + + S K L LF
Sbjct: 540 KPRLS----NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
Query: 625 --------------VGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTH 670
T A+ G+ G K +TV FR +L+ LM L +T
Sbjct: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHK-KTVGHQFRNSLHLLMETLNATT 654
Query: 671 PHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLN 730
PH+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 655 PHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM 714
Query: 731 ASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLIT 790
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL
Sbjct: 715 KQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACI 771
Query: 791 RTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETE 850
R Q RG+L R +Y +M R++ +Q VR + + Y K K+A
Sbjct: 772 RIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQ-------ARCYAKFLRRTKAATII 821
Query: 851 KEMANMKEEFEKTKEELAKT-------------EAKRKELEEKMVTLMQE---------- 887
++ M + K A T RK L E ++Q+
Sbjct: 822 QKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTH 881
Query: 888 -KNDL-----------QLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 935
K + ++ + E L ++ K I +E KI ++ + +++ +
Sbjct: 882 YKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNK 941
Query: 936 INAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 991
L K LE E +L+ D++ L+L+ E+E +V +L EE+A L +
Sbjct: 942 DYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRK 997
Query: 992 TIAKLTKEKKALQE---AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKI 1048
+ + EKK ++E ++Q + L + + NTL K E+E
Sbjct: 998 DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQ---------------EKEALN 1042
Query: 1049 RMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF--EMSGLQSKIEDEQALGM 1106
+++AK E K E T +E D DE+L+ + E S L+ + +D
Sbjct: 1043 HRIVQQAKEMTETMEKKLVEETKQLELDLN--DERLRYQNLLNEFSRLEERYDD------ 1094
Query: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
K+ L + + + S ++E S E+E+I R EE ++
Sbjct: 1095 --LKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP-SEKKVPLD 1151
Query: 1167 MN-----KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
M+ +KR E ++ ++ +++ + E + K + G +++ +Q+L
Sbjct: 1152 MSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQEL 1211
Query: 1222 EKEKSEMKMEIDDL--ASNMETVSKAKGNLEKMCRALEDQLS----EIKTKEEEQQRLIN 1275
E E ++K E+++L A + ++ + R L +QL+ E+ ++EE L +
Sbjct: 1212 ESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRS 1271
Query: 1276 DLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAH 1335
L +Q+ +Q + D+K+T+ T +E++ +++K K +A
Sbjct: 1272 QLVSQKEAIQPK--------DDKNTMTDS--------TILLEDV-----QKMKDKGEIAQ 1310
Query: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
A + LL Q + ++ + A+ E+ + EE ++
Sbjct: 1311 AYIGLKETNRLLESQLQSQKRSHENEAEAL---RGEIQSLK-----------EENNRQQQ 1356
Query: 1396 KLAQRLQ-DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454
LAQ LQ E +E ASL+ RL NE DLM +E+ + L K+ + F
Sbjct: 1357 LLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFA 1410
Query: 1455 KILAE 1459
K + E
Sbjct: 1411 KKIGE 1415
Score = 81.6 bits (200), Expect = 7e-15
Identities = 111/538 (20%), Positives = 239/538 (44%), Gaps = 77/538 (14%)
Query: 806 QKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEK----EMANMKEEFE 861
+K+ E+ + C+ + + + KL ++ L S E K + +++EE
Sbjct: 934 RKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIA 993
Query: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 921
K +++L +T +++K +EE QE L ++ E L +E + ++
Sbjct: 994 KLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNH------RIVQ 1047
Query: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
+ KE+TE E +KL +E +L+ D++D L + E E + +
Sbjct: 1048 QAKEMTETME-------------KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDD 1094
Query: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1041
L EEM T + H++T D ++ + ++I +++D+
Sbjct: 1095 LKEEM----------TLMVHVPKPGHKRT--DSTHSSNESEYIFSSEI---AEMEDIPSR 1139
Query: 1042 LEQ--EKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIE 1099
E+ EKK+ +D+ LKL Q+ ++E +KQ + ++L +KE ++ L+SK +
Sbjct: 1140 TEEPSEKKVPLDMSLF-------LKL-QKRVTELEQEKQVMQDELDRKEEQV--LRSKAK 1189
Query: 1100 DEQALGMQLQKKIKELQARIEELE-EEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
+E+ + +I+ + E L+ +E+E+E K + + ++L + L E S A
Sbjct: 1190 EEE------RPQIRGAELEYESLKRQELESE---NKKLKNELNELRKALSEKSAPEVTAP 1240
Query: 1159 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA---ATLRKKHADSVAELGEQIDNLQ 1215
GA + ++ M + + R E L+ + + A K +++ + ++++Q
Sbjct: 1241 GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ 1300
Query: 1216 RVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI- 1274
++K K E ++ + ++ + + S+ + + E AL ++ +K + QQ+L+
Sbjct: 1301 KMKDKGEIAQAYIGLKETNRLLESQLQSQKRSH-ENEAEALRGEIQSLKEENNRQQQLLA 1359
Query: 1275 ------------NDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
L + RL E+ + QL+++D V +L + + F ++I EL+
Sbjct: 1360 QNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1417
Score = 73.9 bits (180), Expect = 1e-12
Identities = 160/739 (21%), Positives = 289/739 (39%), Gaps = 199/739 (26%)
Query: 1084 LKKKEFEMSGLQSK-IEDEQALGMQLQKKIKELQARIEE--------LEEEIEAERASRA 1134
+ K+E + ++++ +E + L + ++ KI +LQ +++E +E+ E +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
Query: 1195 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMC 1253
++HAD + EQ + NL+ L++EK A N V +AK E M
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAKEMTETME 1057
Query: 1254 RALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFT 1313
+ L EE ++L DL +R R Q E+SR
Sbjct: 1058 KKLV----------EETKQLELDLNDERLRYQNLLNEFSR-------------------- 1087
Query: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373
+EE L+EE+ + + H + D E E +SE+A
Sbjct: 1088 --LEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIF-----------SSEIA 1131
Query: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433
+ D RTEE E K L L + + LE+ KQ +Q+E
Sbjct: 1132 EME-----DIPSRTEEPSEKKVPLDMSL------FLKLQKRVTELEQEKQVMQDE----- 1175
Query: 1434 IDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYE 1493
LD+K+ + A+ +++ + AELE + + L +E K+KN
Sbjct: 1176 ------------LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN--- 1220
Query: 1494 ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEA 1553
E+++L + ++E K E+ + E ++ E E
Sbjct: 1221 ------------------ELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLTSVSE-EL 1259
Query: 1554 SLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRN 1613
+ EE ILR QL V +K A + ++ + ++E +Q
Sbjct: 1260 DVRKEEVLILRSQL--------VSQKEAIQPKDDKNTMTDSTILLEDVQ----------- 1300
Query: 1614 DAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKE 1673
K K +G++ + I L NR+ L SQ L+
Sbjct: 1301 -----KMKDKGEIAQAYIGLKETNRL-------------------------LESQ--LQS 1328
Query: 1674 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL-------LDAS--ERVQLLHTQN 1724
Q E A L+ EI+ L+ E+ R +++ Q L ++AS + L +N
Sbjct: 1329 QKRSHENEAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN 1385
Query: 1725 TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL------KKEQD 1778
L+ +K + + +++ +++ ++ E + I+ ++ E + +KE+D
Sbjct: 1386 LDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKD 1445
Query: 1779 TSAHLERMKKNLEQTVKDL 1797
LE K++ ++ VK+L
Sbjct: 1446 FQGMLEYKKEDEQKLVKNL 1464
Score = 53.1 bits (126), Expect = 3e-06
Identities = 101/513 (19%), Positives = 216/513 (42%), Gaps = 104/513 (20%)
Query: 1453 FDKILAEWKQKCEETHAE-LEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511
F +++A+ + K + A +E +K + ++ +++ +E + L + NL+
Sbjct: 896 FRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955
Query: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571
+ TE++ +LE+ LQ + EEA+ + G++L +Q E+ +
Sbjct: 956 IYNSETEKLRS------DLER-----------LQLSEEEAKVA----TGRVLSLQEEIAK 994
Query: 1572 VKSEVDRKIAEK---DEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNE 1628
++ ++++ +EK +E D+ K+ ++V + ++ N ++ +K+
Sbjct: 995 LRKDLEQTRSEKKCIEEHADRYKQETEQLV--------SNLKEENTLLKQEKE------- 1039
Query: 1629 MEIQLNHANRMAAEALRNYRNTQAILKDTQLHL---DDALRSQEDLKEQLAMVERRANLL 1685
LNH A+ + + + + QL L D+ LR Q L E + ER +L
Sbjct: 1040 ---ALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK 1096
Query: 1686 QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEM 1745
EE+ + + K R H+ N S E S EM
Sbjct: 1097 ----EEMTLMVHVPKPGHK-----------RTDSTHSSNES--------EYIFSSEIAEM 1133
Query: 1746 EDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1805
EDI +R E KK D ++ + L++ LEQ + +Q LD E
Sbjct: 1134 EDI--PSRTEEPSEKKVPLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKE 1180
Query: 1806 QLALKGGKKQIQKLEARVRELE------GEVESEQKRNVEAVKGLRK--HERKVKELTYQ 1857
+ L+ K+ ++ + R ELE E+ESE K+ + LRK E+ E+T
Sbjct: 1181 EQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAP 1240
Query: 1858 TEEDRKNILRLQDLVDK-----------LQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHE 1906
+ ++ V + L++++ S K + ++++ + S + +
Sbjct: 1241 GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTI--LLED 1298
Query: 1907 LEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
+++ +++ +IA++ + L+ +R + +++ S++
Sbjct: 1299 VQKMKDKGEIAQAYIG-LKETNRLLESQLQSQK 1330
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 570 bits (1468), Expect = e-162
Identities = 463/1607 (28%), Positives = 773/1607 (48%), Gaps = 191/1607 (11%)
Query: 36 TSVFVVDPKESFVKA--TVQSREGGK-----VTAKTEAGATVTVKDDQV-FPMNPPKYDK 87
T V++ DP E + A T +EG K + +T + V+ +Q+ F NP
Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
Query: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGK 146
D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
Query: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
Query: 207 KEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239
Query: 267 ETYLLEKSRVTFQLKAERSYHIFYQIMSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVP 324
TYLLEKSRV FQ ER+YHIFYQ+ + P+ E+ L T+ D+ + SQG + ++
Sbjct: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297
Query: 325 SIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE-- 382
+DD E+ T A +LG ++SI+K+ +++H G++ QAE DG
Sbjct: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350
Query: 383 VADKAAYLQN------LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYD 436
++ + YL N + + + LC+ ++ +E K ++QQV NA ALAK +Y
Sbjct: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410
Query: 437 KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470
Query: 497 FVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
F LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLY
Sbjct: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529
Query: 557 EQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSA 616
++H S +FQKP+ + F ++H+A V+Y G+L+KN+D + E + + + S
Sbjct: 530 DRH-SSSQHFQKPRMS----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584
Query: 617 MKTLALLFVGATGAEAEAGGGKKGGKK-------------KGSSFQTVSALFRENLNKLM 663
+A LF GK K +TV FR +L+ LM
Sbjct: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644
Query: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF
Sbjct: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704
Query: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDE 783
RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R +
Sbjct: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762
Query: 784 KLAQLITRTQAMCRGFLARVEYQKMVERRESI--FCIQYNVRA----FMNVKHWPWMKLY 837
K Q RG+L +V+Y ++ ++ +C + R ++ ++ +
Sbjct: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
Query: 838 FKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQA 897
++++ ++ + + A + + F T+ + ++ +E K T+ +K+ +
Sbjct: 823 YRMQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTI--QKHVRGWMARR 878
Query: 898 EADSLADAE---ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK----KRKLEDE 950
L DA + +++K + +L+A ++ AE + +N + K +RK++++
Sbjct: 879 HFQRLRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ 937
Query: 951 CSELKKDIDDLELTLAK------------VEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
E K + L +T + V ++ E+ L EE+ L + +
Sbjct: 938 NKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHS 997
Query: 999 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRK 1058
E+K L++AH + D+L+ ++V D LEQE + L+ K +
Sbjct: 998 ERKILEDAHSREKDELR-----------------KRVAD----LEQENAL---LKDEKEQ 1033
Query: 1059 LEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQAR 1118
L + L Q +N + E L KKE +E+E++ L K+ +L+ R
Sbjct: 1034 LNNQI-LCQSKDEFAQN---SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQR 1080
Query: 1119 IEELEEE--IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176
+ L +E I + + +S L + S E G A
Sbjct: 1081 YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA------------- 1127
Query: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236
+ +EE L+ A T+ K V EL ++ LQ +K E++ S+ A
Sbjct: 1128 --LQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQ-----A 1180
Query: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296
+T N + +L+ Q E++++ ++ + +N+L A T++ D
Sbjct: 1181 EPPQTDIDLDPNADLAYNSLKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHGSPD 1238
Query: 1297 EKDTLVSQLSRGKQAFTQQIEE---LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353
L++QL + + EE L+ Q+ + + A +A + +
Sbjct: 1239 SYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHV 1298
Query: 1354 EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-DAEEHVEAV 1411
+QE E + + NS+ W E + + L++ + L +LQ + EH E V
Sbjct: 1299 DQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEV 1358
Query: 1412 NAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1471
A LE K+ +DK+Q+ F + L E E
Sbjct: 1359 EHLKAQLEALKEE---------------------MDKQQQTFCQTLL----LSPEAQVEF 1393
Query: 1472 EASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL--TEQIAEGGKRIHE 1529
Q+ SR L+ E +K E+ LK++ K ++ DL + +A+ ++ HE
Sbjct: 1394 GVQQEISR-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHE 1452
Query: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1576
L + + V++++ + Q LE H+E + L I+ + +K ++
Sbjct: 1453 LNR-QVTVQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
Score = 63.5 bits (153), Expect = 2e-09
Identities = 124/662 (18%), Positives = 268/662 (40%), Gaps = 69/662 (10%)
Query: 1178 MRRDLEEATLQHEATAAT------LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1231
+RR + ++H+AT + ++H + + I R+ K +E +++E
Sbjct: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
Query: 1232 IDDLASNMETVSKAKGN-LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGE 1290
A +++ ++ N + ++ R +++Q E KT E+ + T + RL+ E
Sbjct: 910 ARS-AEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVH 968
Query: 1291 YSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 1350
Y + E +L Q +++E L+ +L+ + L A + D LR++
Sbjct: 969 YQQSPGEDTSLRLQ---------EEVESLRTELQRAHSERKILEDAHSREK---DELRKR 1016
Query: 1351 YEEEQEAKAELQRAMSKANSEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQRLQD 1403
+ ++ A L+ + N+++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQ 1076
Query: 1404 AEEHVEAVNAKCASLEKTKQRLQN--EVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
E+ + + + +++T +N L D + + + + + ++
Sbjct: 1077 LEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGL 1136
Query: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEIS-DLTEQI 1520
+K QK R L E K++ E+ +Q ++ K + + Q +I D +
Sbjct: 1137 EKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDLDPNADL 1195
Query: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
A + ELE K+++ + +EL+ A+ + G L LNQ+K
Sbjct: 1196 AYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL------ 1249
Query: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
EE++ K + + + S + RN + + +E + A
Sbjct: 1250 --AHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD----QEDA 1303
Query: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700
EA T + +D L +L +++ A LL+A+++ E+
Sbjct: 1304 IEAYHGVCQTNSKTEDW-----GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEV 1358
Query: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE----TDISQIQGE---MEDIIQEAR 1753
K + L + ++ Q Q T L++ + ++E +IS++ E +++++++
Sbjct: 1359 EHLKAQLEALKEEMDKQQQTFCQ-TLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLE 1417
Query: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV------KDLQ-----HRLD 1802
E K KK + A++L+ Q A ER + L + V KD Q H+ D
Sbjct: 1418 KNERKLKKQLKIYMKKAQDLEAAQ-ALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKED 1476
Query: 1803 EA 1804
EA
Sbjct: 1477 EA 1478
Score = 45.8 bits (107), Expect = 4e-04
Identities = 70/343 (20%), Positives = 142/343 (41%), Gaps = 48/343 (13%)
Query: 1605 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDA 1664
L E RS RL ME + +++ +++ N+ ++ + T + +
Sbjct: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTL------SEQLSVTTSTYTMEV 959
Query: 1665 LRSQEDLKE-QLAMVERRANLLQAEIEELRATLEQTERSRKIAE----QELLDASERVQL 1719
R +++L Q + E + LQ E+E LR L++ RKI E +E + +RV
Sbjct: 960 ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019
Query: 1720 LHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDT 1779
L +N L + K++L +QI + +D + E KK + + + L KE
Sbjct: 1020 LEQENALLKDEKEQLN---NQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEY-- 1074
Query: 1780 SAHLERMKKNLEQTVKDLQ----HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1835
+ LE+ NL + ++ HR + + Q +L+ + + + E ++ ++
Sbjct: 1075 -SQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEE 1133
Query: 1836 RNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNV 1895
+E + D L+LQ V +L+ + K + Q E+ E+Q +
Sbjct: 1134 IGLE-----------------KAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDS- 1175
Query: 1896 NLSKFRRIQHELEEA----EERADIAESQVNKLRVKSREVHTK 1934
+++Q E + + AD+A + + + ++S K
Sbjct: 1176 -----KKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLK 1213
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 511 bits (1315), Expect = e-144
Identities = 431/1697 (25%), Positives = 811/1697 (47%), Gaps = 218/1697 (12%)
Query: 58 GKVTAKTEA-GATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
GKV K + GA + V +D V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
Query: 117 TYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
Query: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNA 236
+ G SG+GKT + + ++QY ATIA K V + T LLEAFGN+
Sbjct: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYT----------LLEAFGNS 545
Query: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-- 294
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +++
Sbjct: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
Query: 295 --NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSI 352
+ +L L N + +++ E + +L A A+++LG + DE+ +
Sbjct: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
Query: 353 YKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQNLNSADLLKALCYPRVKVG- 410
+ + A+ H G ++ E + E A KAAYL + +L A+ + K G
Sbjct: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
Query: 411 ---NEYVTKGQTVQQVYNAVG----------ALAKAVYDKMFLWMVTRINQQLDTKQPRQ 457
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
Query: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
Query: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
Query: 557 EQHLGKSNN--FQKPKPAKGKPEAHFSLIHYAGT--VDYNIAGWLDKNK-DPLNETVVGL 611
+ + + Q P KP HF L H GT V+YN+ GWL+ K +P + L
Sbjct: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
Query: 612 YQKSAMKTLALLFVGATGAEAEAGG---GKKGGKKKG--------SSFQTVSALFRE--- 657
Q S K ++ LF+G G+ G G +GG + +F T A ++
Sbjct: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
Query: 658 ------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 687
++ L+ ++ + HFV C +P +E P
Sbjct: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
Query: 688 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 738
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
Query: 739 FIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRG 798
+D ++A E+LL +D++ + G ++VFF+AG L LEE RDE+ ++ +T QA CRG
Sbjct: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
Query: 799 FLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
+LAR ++K + +I C+Q N++ VK WPW KL+ ++PL++ +E+++ N E
Sbjct: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
Query: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQ 918
E ++ + +L K E +R EL L ++L ++ E ++ A + D +++
Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
Query: 919 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 973
E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
Query: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1029
+ K L +E ++ + + K+ L ++ L DLQA+ ++ + L K
Sbjct: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
Query: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF 1089
+L ++ D + LE ++ +LE+ +R+ + +L A E + +++L +
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 1090 EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
E L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++
Sbjct: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGE 1209
E L+E G I+M LE+A L+ E +R+ H+ + E
Sbjct: 1554 QEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMESRDE 1595
Query: 1210 QIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEE 1269
++ + +Q +K+ +M++++++ + + V + K LE L DQ++ + E
Sbjct: 1596 EV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFES 1650
Query: 1270 QQRLINDLTAQRARL----------------QTESGEYSRQLDEKDTLVSQLSRGKQAFT 1313
++RL DL +A L + E + QL+E + + + ++A
Sbjct: 1651 EKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME 1710
Query: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373
+IE+L Q+++ KAK+AL L + + + ++ + EE+QE EL M K + VA
Sbjct: 1711 VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVA 1767
Query: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433
Q A + LAQ + D + +E N + L++ Q LQ++VE L
Sbjct: 1768 Q------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL- 1807
Query: 1434 IDVERTNAACAALDKKQRNFDKILA---EWKQKCEETHAELEASQ-KESRSLSTELFKIK 1489
+Q DK L E K + ET E E +Q K SL++ L +
Sbjct: 1808 ---------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
Query: 1490 NAYEESLDQL----ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 1545
E DQ K +NK LQ+++ D E++ E ++ E + K ++E + L+
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1912
Query: 1546 AALEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKI--AEKDEEIDQMKRNHIRIVESMQ 1602
AA + +A L+ +I +Q + ++++S+ + + +E D ++D + + V+S
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWL 1972
Query: 1603 STLDAEIRSRNDAIRLK 1619
S ++ +D LK
Sbjct: 1973 SKNKGPSKAASDDGSLK 1989
Score = 194 bits (494), Expect = 5e-49
Identities = 156/687 (22%), Positives = 334/687 (48%), Gaps = 47/687 (6%)
Query: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL-DEKDT--LVSQLS 1306
E+ R ++++ ++++K E+ ++ N+L RL++ E + +L DE++T SQL
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1307 RGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY----EEEQEAKAELQ 1362
+ A + E+ ++L+ + A ++ + L+R ++ +A E +
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422
+A EV + + + + + E ++ K++L +RL D + E L+K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1423 QRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLS 1482
QRL E++D + +E L+KKQR FD L++ ++ + + E Q+E L
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
Query: 1483 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKS 1542
E F +K EE + ++ +L+ E+ D++ Q ++ + +++K + +E +
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
Query: 1543 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
+ + L+E +++ E LR+++E+ +++ +++ +DEE+++ +++ + ++ M+
Sbjct: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
Query: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQAILKDTQLHL 1661
L+ E + +R K+++EG L + Q+N + + + LR + + T+A+L D QL L
Sbjct: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
Query: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721
D L++ K ++A L+ ++EE T ++RK E E+ D LH
Sbjct: 1673 DH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-------LH 1717
Query: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Q + K LE +S++Q E +I +E M E +KK + A
Sbjct: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
Query: 1782 HLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841
+ + ++L Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE ++ V+
Sbjct: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
Query: 1842 KGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFR 1901
+ + E K++EL + E +R + RL+ L +L+ ++ + ++ N + +
Sbjct: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
Query: 1902 RIQHELEEA-EERADIAESQVNKLRVK 1927
R+Q +L + EE ++A + R K
Sbjct: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
Score = 150 bits (378), Expect = 2e-35
Identities = 184/830 (22%), Positives = 374/830 (45%), Gaps = 117/830 (14%)
Query: 943 KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 992
++R +E+ EC +L+K + L TLA++E+++ E +NLT A
Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202
Query: 993 IAKLTKEKKALQEAH----QQTLDDLQAEED----KVNTLTKAKIKLEQQVDDLEGSLEQ 1044
+A+ +K+ +Q+ Q+ + + +D K+ T + I+++ + + E+
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262
Query: 1045 EKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQAL 1104
+++R LE+A+++ +L+L + +E+ +L +L + ++ E A
Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDR---LESRISELTSELTDERNTGESASQLLDAETAE 1318
Query: 1105 GMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1163
++ +K++KELQ + + L++++E +A R+ +++ E+++ ++AGG
Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373
Query: 1164 QIEMNKKREAEFQKMR--RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
+ E RE +F K R ++ E+ + L ++ D A+ E QR Q+L
Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428
Query: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQR 1281
+K+ + E+ D ++E LEK R + +LS+ + + ++ L ++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488
Query: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEE----EIKAKSALAHAL 1337
L E+ +QL+EKD ++ FTQ++ L+ +L++ E K +++LA
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIA-------GFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 1338 QSSRHDCDLLREQYEEEQEAKAELQ---RAMSKANSEVAQWRTKYETDAIQRTEELEEAK 1394
+ R +++Q EE E +Q +A + E+ + R + + R EE+EEA+
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
Query: 1395 KKLAQRLQDAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMIDVERT 1439
+ ++L+ E +E + K A+L R E E L D++RT
Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
Query: 1440 NAACA----ALD--KKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTEL-------- 1485
A A LD K + +A+ K + EE+ A+ K +++ E+
Sbjct: 1662 KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721
Query: 1486 --FKIKNAYEESLDQLETLKRENKN-LQQEISDLTE-------QIAEGGKRIHELEKIKK 1535
K K A EE L +L+ K E +N L+++ D+ E +A+ + + ++ ++
Sbjct: 1722 DIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQA 1781
Query: 1536 QVEQ---EKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKR 1592
Q+E+ EK ELQ L+ ++ +E E ++ L Q + KI E + ++ +R
Sbjct: 1782 QLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-----EAKIRELETRLE-FER 1835
Query: 1593 NHIRIVESMQSTL-----------DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
++ +ES+ S L D I + N K+++ L + + ++ R A
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA 1895
Query: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1691
EA R + ++ L+ + + L+ L + +R LQA IE+
Sbjct: 1896 EASRKKH-------ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938
Score = 105 bits (262), Expect = 4e-22
Identities = 137/611 (22%), Positives = 266/611 (43%), Gaps = 104/611 (17%)
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQDA 1404
+R + EE Q+ +++L++A K +E+ + E+ + T EL + + + A +L DA
Sbjct: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
Query: 1405 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462
E E + A + L+ L+ ++E + ++V AA + + D EW+
Sbjct: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
Query: 1463 KCE---------------ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENK 1507
K E E +LE Q+ R L L ++ EES L+ LK++ +
Sbjct: 1374 KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQ 1433
Query: 1508 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQL 1567
L E+ D + R HELEK +++ + SEL A EEA+ R +L
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFD---SELSQAHEEAQ-----------REKL 1479
Query: 1568 ELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1627
+ +++ E D +AE Q++ + I Q + +E +L
Sbjct: 1480 QREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVS---------------LEAELQ 1524
Query: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687
++ Q + A+ + R+ +A +KD + LD+ + + M+E+ L+
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEM 1577
Query: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747
E+E +R T + SR ++E+ +A + Q KKL+ Q++ E ED
Sbjct: 1578 EMERMRQTHSKEMESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYED 1621
Query: 1748 ---IIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 1801
+++E R E K A +++++ + S +R++K+L++T + D Q L
Sbjct: 1622 KQKVLREKRELEGKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLML 1672
Query: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEED 1861
D + A + + +L+ ++E + AVK + E ++++L Q ++
Sbjct: 1673 DHLKNSAPS---------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 1862 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921
K L++ + +LQ + + + EE +E N + K H+ A+ D+A Q+
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QI 1776
Query: 1922 NKLRVKSREVH 1932
N L+ + E +
Sbjct: 1777 NDLQAQLEEAN 1787
Score = 87.8 bits (216), Expect = 9e-17
Identities = 95/481 (19%), Positives = 211/481 (43%), Gaps = 47/481 (9%)
Query: 1496 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAAL------- 1548
L +++ + + +N +EI L ++ + K +EL ++E SEL + L
Sbjct: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
Query: 1549 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAE 1608
E A L+ E + LR + E+ +++++ D +K E+ +M+ R++ + + + +
Sbjct: 1306 ESASQLLDAETAERLRAEKEMKELQTQYD--ALKKQMEVMEMEVMEARLIRAAEINGEVD 1363
Query: 1609 IRSRNDAIRLKKK---MEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDAL 1665
RLK + E D + +Q +++ E +N R + L D Q +++
Sbjct: 1364 DDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ-QNKRQLERRLGDLQADSEESQ 1422
Query: 1666 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1725
R+ + LK++ + + +E + + E+ ++ + EL A E Q Q
Sbjct: 1423 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1482
Query: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
L K L + ++ ++E+ + +K + ++ + K++ + A +++
Sbjct: 1483 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1542
Query: 1786 MKKNLEQTVKDLQHRLDEAEQL--ALKGGKKQIQKLEARVRELEG-EVESEQKRNVEAVK 1842
++LE VKD + LDE L+ K +++ R+R+ E+ES R+ E +
Sbjct: 1543 QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES---RDEEVEE 1599
Query: 1843 GLRKHERKVKELTYQTE---EDRKNILR-LQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
+ ++K+K++ Q E ED++ +LR ++L KL R+ E+E++ +L
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLK 1659
Query: 1899 KFR------------------------RIQHELEEAEERADIAESQVNKLRVKSREVHTK 1934
+ + +++++LEE+E A + V+ ++H +
Sbjct: 1660 RTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ 1719
Query: 1935 I 1935
I
Sbjct: 1720 I 1720
Score = 82.0 bits (201), Expect = 5e-15
Identities = 68/301 (22%), Positives = 147/301 (48%), Gaps = 11/301 (3%)
Query: 1648 RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1707
RN ++ + L+ A + + +L+ +E R + L +E+ + R T E +
Sbjct: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
Query: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIIQEARNAEEKA 1759
E L A + ++ L TQ +L + +E ++ ++I GE++D K
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
Query: 1760 KKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
++A+ + + L++E + +E+ K+ LE+ + DLQ +E+++ AL+ KK+ Q+
Sbjct: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
Query: 1819 LEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
L A +++ + +E +Q RN E K R+ + ++ + + + ++ +LQ D L A+
Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
Query: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISE 1938
S K+Q EE + K ++ EL++ + E+ + K++ + R++ K+ +
Sbjct: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
Query: 1939 E 1939
E
Sbjct: 1555 E 1555
Score = 35.0 bits (79), Expect = 0.71
Identities = 36/172 (20%), Positives = 79/172 (45%), Gaps = 16/172 (9%)
Query: 1772 ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK-----------LE 1820
E ++++ TS +L + + + + + LA++ +K I+K L
Sbjct: 1181 EEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLF 1240
Query: 1821 ARVREL-EGEVESEQKRNV-EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
VR L E ++ EQ RN E ++ LR K+++ + E R N RL+ + +L ++
Sbjct: 1241 TTVRPLIEVQLSEEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSE 1297
Query: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSRE 1930
+ + E A + + ++ R + E++E + + D + Q+ + ++ E
Sbjct: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 510 bits (1313), Expect = e-144
Identities = 428/1693 (25%), Positives = 809/1693 (47%), Gaps = 217/1693 (12%)
Query: 58 GKVTAKTEA-GATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
GKV K + GA + V +D V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
Query: 117 TYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
Query: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNA 236
+ G SG+GKT + + ++QY ATIA K V + T LLEAFGN+
Sbjct: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYT----------LLEAFGNS 545
Query: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-- 294
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +++
Sbjct: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
Query: 295 --NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSI 352
+ +L L N + +++ E + +L A A+++LG + DE+ +
Sbjct: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
Query: 353 YKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQNLNSADLLKALCYPRVKVG- 410
+ + A+ H G ++ E + E A KAAYL + +L A+ + K G
Sbjct: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
Query: 411 ---NEYVTKGQTVQQVYNAVG----------ALAKAVYDKMFLWMVTRINQQLDTKQPRQ 457
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
Query: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
Query: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
Query: 557 EQHLGKSNN--FQKPKPAKGKPEAHFSLIHYAGT--VDYNIAGWLDKNK-DPLNETVVGL 611
+ + + Q P KP HF L H GT V+YN+ GWL+ K +P + L
Sbjct: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
Query: 612 YQKSAMKTLALLFVGATGAEAEAGG---GKKGGKKKG--------SSFQTVSALFRE--- 657
Q S K ++ LF+G G+ G G +GG + +F T A ++
Sbjct: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
Query: 658 ------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 687
++ L+ ++ + HFV C +P +E P
Sbjct: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
Query: 688 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 738
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
Query: 739 FIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRG 798
+D ++A E+LL +D++ + G ++VFF+AG L LEE RDE+ ++ +T QA CRG
Sbjct: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
Query: 799 FLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
+LAR ++K + +I C+Q N++ VK WPW KL+ ++PL++ +E+++ N E
Sbjct: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
Query: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQ 918
E ++ + +L K E +R EL L ++L ++ E ++ A + D +++
Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
Query: 919 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 973
E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
Query: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1029
+ K L +E ++ + + K+ L ++ L DLQA+ ++ + L K
Sbjct: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
Query: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF 1089
+L ++ D + LE ++ +LE+ +R+ + +L A E + +++L +
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 1090 EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
E L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++
Sbjct: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGE 1209
E L+E G I+M LE+A L+ E +R+ H+ + E
Sbjct: 1554 QEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMESRDE 1595
Query: 1210 QIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEE 1269
++ + +Q +K+ +M++++++ + + V + K LE L DQ++ + E
Sbjct: 1596 EV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFES 1650
Query: 1270 QQRLINDLTAQRARL----------------QTESGEYSRQLDEKDTLVSQLSRGKQAFT 1313
++RL DL +A L + E + QL+E + + + ++A
Sbjct: 1651 EKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME 1710
Query: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373
+IE+L Q+++ KAK+AL L + + + ++ + EE+QE EL M K + VA
Sbjct: 1711 VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVA 1767
Query: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433
Q A + LAQ + D + +E N + L++ Q LQ++VE L
Sbjct: 1768 Q------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL- 1807
Query: 1434 IDVERTNAACAALDKKQRNFDKILA---EWKQKCEETHAELEASQ-KESRSLSTELFKIK 1489
+Q DK L E K + ET E E +Q K SL++ L +
Sbjct: 1808 ---------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
Query: 1490 NAYEESLDQL----ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 1545
E DQ K +NK LQ+++ D E++ E ++ E + K ++E + L+
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1912
Query: 1546 AALEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQST 1604
AA + +A L+ +I +Q + ++++S+ + + +++ + +E S
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEG-DSD 1971
Query: 1605 LDAEIRSRNDAIR 1617
+D+E+ R D ++
Sbjct: 1972 VDSELEDRVDGVK 1984
Score = 194 bits (494), Expect = 5e-49
Identities = 156/687 (22%), Positives = 334/687 (48%), Gaps = 47/687 (6%)
Query: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL-DEKDT--LVSQLS 1306
E+ R ++++ ++++K E+ ++ N+L RL++ E + +L DE++T SQL
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1307 RGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY----EEEQEAKAELQ 1362
+ A + E+ ++L+ + A ++ + L+R ++ +A E +
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422
+A EV + + + + + E ++ K++L +RL D + E L+K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1423 QRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLS 1482
QRL E++D + +E L+KKQR FD L++ ++ + + E Q+E L
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
Query: 1483 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKS 1542
E F +K EE + ++ +L+ E+ D++ Q ++ + +++K + +E +
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
Query: 1543 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
+ + L+E +++ E LR+++E+ +++ +++ +DEE+++ +++ + ++ M+
Sbjct: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
Query: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQAILKDTQLHL 1661
L+ E + +R K+++EG L + Q+N + + + LR + + T+A+L D QL L
Sbjct: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
Query: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721
D L++ K ++A L+ ++EE T ++RK E E+ D LH
Sbjct: 1673 DH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-------LH 1717
Query: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Q + K LE +S++Q E +I +E M E +KK + A
Sbjct: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
Query: 1782 HLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841
+ + ++L Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE ++ V+
Sbjct: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
Query: 1842 KGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFR 1901
+ + E K++EL + E +R + RL+ L +L+ ++ + ++ N + +
Sbjct: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
Query: 1902 RIQHELEEA-EERADIAESQVNKLRVK 1927
R+Q +L + EE ++A + R K
Sbjct: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
Score = 158 bits (400), Expect = 4e-38
Identities = 205/919 (22%), Positives = 404/919 (43%), Gaps = 134/919 (14%)
Query: 943 KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 992
++R +E+ EC +L+K + L TLA++E+++ E +NLT A
Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202
Query: 993 IAKLTKEKKALQEAH----QQTLDDLQAEED----KVNTLTKAKIKLEQQVDDLEGSLEQ 1044
+A+ +K+ +Q+ Q+ + + +D K+ T + I+++ + + E+
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262
Query: 1045 EKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQAL 1104
+++R LE+A+++ +L+L + +E+ +L +L + ++ E A
Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDR---LESRISELTSELTDERNTGESASQLLDAETAE 1318
Query: 1105 GMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1163
++ +K++KELQ + + L++++E +A R+ +++ E+++ ++AGG
Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373
Query: 1164 QIEMNKKREAEFQKMR--RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
+ E RE +F K R ++ E+ + L ++ D A+ E QR Q+L
Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428
Query: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQR 1281
+K+ + E+ D ++E LEK R + +LS+ + + ++ L ++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488
Query: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEE----EIKAKSALAHAL 1337
L E+ +QL+EKD ++ FTQ++ L+ +L++ E K +++LA
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIA-------GFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 1338 QSSRHDCDLLREQYEEEQEAKAELQ---RAMSKANSEVAQWRTKYETDAIQRTEELEEAK 1394
+ R +++Q EE E +Q +A + E+ + R + + R EE+EEA+
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
Query: 1395 KKLAQRLQDAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMIDVERT 1439
+ ++L+ E +E + K A+L R E E L D++RT
Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
Query: 1440 NAACA----ALD--KKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTEL-------- 1485
A A LD K + +A+ K + EE+ A+ K +++ E+
Sbjct: 1662 KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721
Query: 1486 --FKIKNAYEESLDQLETLKRENKN-LQQEISDLTE-------QIAEGGKRIHELEKIKK 1535
K K A EE L +L+ K E +N L+++ D+ E +A+ + + ++ ++
Sbjct: 1722 DIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQA 1781
Query: 1536 QVEQ---EKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKR 1592
Q+E+ EK ELQ L+ ++ +E E ++ L Q + KI E + ++ +R
Sbjct: 1782 QLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-----EAKIRELETRLE-FER 1835
Query: 1593 NHIRIVESMQSTL-----------DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
++ +ES+ S L D I + N K+++ L + + ++ R A
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA 1895
Query: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
EA R + ++ L+ + + L+ L + +R LQA IE+
Sbjct: 1896 EASRKKH-------ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED---------- 1938
Query: 1702 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761
E E + + + L T K KLE D S + E+ED + ++ K K
Sbjct: 1939 -----EMESDENEDLINSLQDMVTKYQKRKNKLEGD-SDVDSELEDRVDGVKSWLSK-NK 1991
Query: 1762 AITDAAMMAEELKKEQDTS 1780
+ AA LK TS
Sbjct: 1992 GPSKAASDDGSLKSSSPTS 2010
Score = 105 bits (262), Expect = 4e-22
Identities = 137/611 (22%), Positives = 266/611 (43%), Gaps = 104/611 (17%)
Query: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQDA 1404
+R + EE Q+ +++L++A K +E+ + E+ + T EL + + + A +L DA
Sbjct: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
Query: 1405 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462
E E + A + L+ L+ ++E + ++V AA + + D EW+
Sbjct: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
Query: 1463 KCE---------------ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENK 1507
K E E +LE Q+ R L L ++ EES L+ LK++ +
Sbjct: 1374 KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQ 1433
Query: 1508 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQL 1567
L E+ D + R HELEK +++ + SEL A EEA+ R +L
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFD---SELSQAHEEAQ-----------REKL 1479
Query: 1568 ELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1627
+ +++ E D +AE Q++ + I Q + +E +L
Sbjct: 1480 QREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVS---------------LEAELQ 1524
Query: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687
++ Q + A+ + R+ +A +KD + LD+ + + M+E+ L+
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEM 1577
Query: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747
E+E +R T + SR ++E+ +A + Q KKL+ Q++ E ED
Sbjct: 1578 EMERMRQTHSKEMESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYED 1621
Query: 1748 ---IIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 1801
+++E R E K A +++++ + S +R++K+L++T + D Q L
Sbjct: 1622 KQKVLREKRELEGKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLML 1672
Query: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEED 1861
D + A + + +L+ ++E + AVK + E ++++L Q ++
Sbjct: 1673 DHLKNSAPS---------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 1862 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921
K L++ + +LQ + + + EE +E N + K H+ A+ D+A Q+
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QI 1776
Query: 1922 NKLRVKSREVH 1932
N L+ + E +
Sbjct: 1777 NDLQAQLEEAN 1787
Score = 82.0 bits (201), Expect = 5e-15
Identities = 68/301 (22%), Positives = 147/301 (48%), Gaps = 11/301 (3%)
Query: 1648 RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1707
RN ++ + L+ A + + +L+ +E R + L +E+ + R T E +
Sbjct: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
Query: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIIQEARNAEEKA 1759
E L A + ++ L TQ +L + +E ++ ++I GE++D K
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
Query: 1760 KKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
++A+ + + L++E + +E+ K+ LE+ + DLQ +E+++ AL+ KK+ Q+
Sbjct: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
Query: 1819 LEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
L A +++ + +E +Q RN E K R+ + ++ + + + ++ +LQ D L A+
Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
Query: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISE 1938
S K+Q EE + K ++ EL++ + E+ + K++ + R++ K+ +
Sbjct: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
Query: 1939 E 1939
E
Sbjct: 1555 E 1555
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/267 (25%), Positives = 125/267 (46%), Gaps = 44/267 (16%)
Query: 1674 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733
++ + E + EI++LR+ LE+ E+ R EL S+R
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
Query: 1734 LETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNL 1790
LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK +
Sbjct: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
Query: 1791 E-QTVKDLQHRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNV 1838
E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K V
Sbjct: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
Query: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
E + R+ ER++ +L +EE ++ + +L+ +L A+++ K E + +++
Sbjct: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
Query: 1899 KFRRIQHELEEAEERADIAESQVNKLR 1925
K RR EL +A E A + Q KL+
Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
Score = 35.0 bits (79), Expect = 0.71
Identities = 36/172 (20%), Positives = 79/172 (45%), Gaps = 16/172 (9%)
Query: 1772 ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK-----------LE 1820
E ++++ TS +L + + + + + LA++ +K I+K L
Sbjct: 1181 EEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLF 1240
Query: 1821 ARVREL-EGEVESEQKRNV-EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
VR L E ++ EQ RN E ++ LR K+++ + E R N RL+ + +L ++
Sbjct: 1241 TTVRPLIEVQLSEEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSE 1297
Query: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSRE 1930
+ + E A + + ++ R + E++E + + D + Q+ + ++ E
Sbjct: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 481 bits (1239), Expect = e-135
Identities = 315/969 (32%), Positives = 539/969 (55%), Gaps = 55/969 (5%)
Query: 32 FDAKTSVFVVDPKESFVKATVQSREGGKVTAKTEAGATVTVKDD-----QVFPMNPPKYD 86
F T V++ + + F +TV S G V +T+ G T K +V M+P +
Sbjct: 5 FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63
Query: 87 KIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYNAEVVTAYRG 145
++DMA +T LH +++YNL +RY IYTY G +VNPY+ + +Y + Y
Sbjct: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123
Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
+ E PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ + I+ +
Sbjct: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS----Q 179
Query: 206 KKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
+ E++ + +E I+ ++P++EAFGNAKTV N+NSSRFGKF++++ G +
Sbjct: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
Query: 266 IETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQ-GEITVP 324
I YLLEK+RV Q ER+YHIFY +++ + + E ++T P +Y +++Q G +
Sbjct: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDK 298
Query: 325 SIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA 384
+I DQE +A++++ F+ +E + +L ++H GN++F A+
Sbjct: 299 TISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTAL 355
Query: 385 DKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVT 444
++A L L+ L AL + + E + VQQ ++ +LA A+Y F W++
Sbjct: 356 GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415
Query: 445 RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
+IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ++FN H+F LEQ EY
Sbjct: 416 KINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474
Query: 505 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSN 564
+EG+ W ID+ +D C++LIEK +G+ +++ EE FP+ATD++ KL+ QH ++
Sbjct: 475 SREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNH 532
Query: 565 NFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF 624
+ KP+ A +F + HYAG V Y++ G L+KN+D + ++ L ++S + LF
Sbjct: 533 FYVKPRVAVN----NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF 588
Query: 625 VGATGAEAEAGGGKKGGKKKGSSFQ--TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 682
E + + K GS + TVS+ F+++L+ LM L S++P FVRCI PN
Sbjct: 589 ------EHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ 642
Query: 683 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS-AIPEGQFID 741
K P + +VL+QLR +G+LE +RI + G+ R + DF +RYKVL + A+PE D
Sbjct: 643 KMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----D 698
Query: 742 SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLA 801
+ LL D +++++ G TKVF + L LE+ R+E+++ +A GFLA
Sbjct: 699 VRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA 758
Query: 802 RVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMK-----LYFKIKPLLKSAETEKEMANM 856
R +Y+K++ + IQ N RAF+ + + +K +++ + + +A
Sbjct: 759 RKQYRKVL---YCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815
Query: 857 KEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTK 916
+E+ EK K+E E ++K+ EE+ +E+ + +L+ Q E ++ E Q K
Sbjct: 816 REQEEKKKQE----EEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQ----K 867
Query: 917 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Q EA++ E+ ++ +++ E+ ++++ED + K+ +L LT A ++K + +
Sbjct: 868 SQKEAELTRELEKQKENKQVE-EILRLEKEIED--LQRMKEQQELSLTEASLQKLQERRD 924
Query: 977 NKVKNLTEE 985
+++ L EE
Sbjct: 925 QELRRLEEE 933
Score = 47.0 bits (110), Expect = 2e-04
Identities = 69/296 (23%), Positives = 137/296 (46%), Gaps = 47/296 (15%)
Query: 858 EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKI 917
++F K + L + A +++ K +L+Q L DA QL KTK+
Sbjct: 680 QDFYKRYKVLMRNLALPEDVRGKCTSLLQ---------------LYDASNSEWQLGKTKV 724
Query: 918 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 977
L +++ E+ +EE +A + + L +K + + ++K A
Sbjct: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKVLYCVVIIQKNYRAFLL 781
Query: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1037
+ + L + A + + + + + ++Q L + + +E+K K E++
Sbjct: 782 RRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKK--------KQEEE--- 827
Query: 1038 LEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKK--KEFEMSG-L 1094
E++K+ + ER + + E +L+ QE E KQQ E L+K KE E++ L
Sbjct: 828 -----EKKKREEEERERERERREAELRAQQEE----ETRKQQELEALQKSQKEAELTREL 878
Query: 1095 QSKIEDEQALG-MQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
+ + E++Q ++L+K+I++LQ R++E ++E+ AS K +++R R LEE
Sbjct: 879 EKQKENKQVEEILRLEKEIEDLQ-RMKE-QQELSLTEASLQKLQERRDQELRRLEE 932
Score = 44.7 bits (104), Expect = 0.001
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 26/199 (13%)
Query: 1291 YSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 1350
+ +QL + + ++ R A ++ EE K+Q EEE K + + R + + LR Q
Sbjct: 795 FQKQL--RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE-LRAQ 851
Query: 1351 YEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKL--AQRLQDAEEHV 1408
EEE + EL+ A+ K+ E R + ++ EE+ +K++ QR+++ +E
Sbjct: 852 QEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE-- 908
Query: 1409 EAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK--KQRNFDKILAEWKQKCEE 1466
++ ASL+K ++R E+ L AC A + + NFD+I +E
Sbjct: 909 --LSLTEASLQKLQERRDQELRRL------EEEACRAAQEFLESLNFDEI--------DE 952
Query: 1467 THAELEASQKESRSLSTEL 1485
+E S S+EL
Sbjct: 953 CVRNIERSLSVGSEFSSEL 971
Score = 43.9 bits (102), Expect = 0.002
Identities = 43/193 (22%), Positives = 84/193 (43%), Gaps = 17/193 (8%)
Query: 1045 EKKIRMDL-ERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQA 1103
+K++R + R R+L + + +E E +K++ +E+ +++E E + + + E+
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855
Query: 1104 LGMQLQKKIKELQARIEELEEEIEAERASRA-----KAEKQRSDLSRELEEISERLEEAG 1158
Q + + + + EL E+E ++ ++ + EK+ DL R E+ L EA
Sbjct: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA- 914
Query: 1159 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1218
+ K +E Q++RR EEA A L + D + E I+ V
Sbjct: 915 -------SLQKLQERRDQELRRLEEEAC---RAAQEFLESLNFDEIDECVRNIERSLSVG 964
Query: 1219 QKLEKEKSEMKME 1231
+ E +E E
Sbjct: 965 SEFSSELAESACE 977
Score = 41.2 bits (95), Expect = 0.010
Identities = 36/174 (20%), Positives = 85/174 (48%), Gaps = 21/174 (12%)
Query: 929 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 988
R + + +L A+KR+ E++ + +++ K ++E+ E + + E+
Sbjct: 800 RGQIARRVYRQLLAEKREQEEKKKQEEEE---------KKKREEEERERERERREAELRA 850
Query: 989 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQE--- 1045
E + +E +ALQ++ ++ + E+ K N + ++LE++++DL+ EQ+
Sbjct: 851 QQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELS 910
Query: 1046 ------KKIRMDLERAKRKLEGD-LKLAQESTMDIENDKQQLDEKLKKKEFEMS 1092
+K++ ++ R+LE + + AQE + D ++DE ++ E +S
Sbjct: 911 LTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFD--EIDECVRNIERSLS 962
Score = 41.2 bits (95), Expect = 0.010
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 1820 EARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV 1879
E R +E + + E E+K+ E + R+ ER+ EL Q EE+ R Q ++ LQ
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
Query: 1880 KSYKRQAEEAEEQSNVNLSKFRRIQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1934
K + E +++ N + + R++ E+E+ ++ + E+ + KL+ + R+ +
Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ-ERRDQELR 928
Query: 1935 IISEE 1939
+ EE
Sbjct: 929 RLEEE 933
Score = 39.7 bits (91), Expect = 0.029
Identities = 46/218 (21%), Positives = 99/218 (45%), Gaps = 39/218 (17%)
Query: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEM-----EDIIQEARNAEEKAKKAITDAAMMA 1770
R + LH + +++ K Q++G++ ++ E R EEK K+
Sbjct: 782 RRRFLHLKKAAIVFQK--------QLRGQIARRVYRQLLAEKREQEEKKKQE-------E 826
Query: 1771 EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830
EE KK ++ ER ++ E + + + E AL+ +K+ + RELE +
Sbjct: 827 EEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAE----LTRELEKQK 882
Query: 1831 ESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILR--LQDLVDKLQAKVKSYKRQAEE 1888
E++Q V+ + + E+++++L E+ ++ LQ L ++ +++ + +A
Sbjct: 883 ENKQ------VEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACR 936
Query: 1889 AEEQ--SNVNLSKF----RRIQHELEEAEE-RADIAES 1919
A ++ ++N + R I+ L E +++AES
Sbjct: 937 AAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAES 974
Score = 39.7 bits (91), Expect = 0.029
Identities = 38/147 (25%), Positives = 75/147 (51%), Gaps = 18/147 (12%)
Query: 1447 DKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKREN 1506
+KK+R + E +++ E AEL A Q+E EL ++ + +E+ + L+++
Sbjct: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEKQK 882
Query: 1507 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQ 1566
+N Q E+I K I +L+++K+Q QE S +A+L++ + E + ++ R++
Sbjct: 883 ENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRRLE 931
Query: 1567 LELNQVKSEVDRKIAEKDEEIDQMKRN 1593
E + E + +EID+ RN
Sbjct: 932 EEACRAAQEFLESL--NFDEIDECVRN 956
Score = 39.3 bits (90), Expect = 0.038
Identities = 42/170 (24%), Positives = 85/170 (50%), Gaps = 22/170 (12%)
Query: 918 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 977
QL A+ +E E+ + EEE +K+K E+E E +++ + EL + E+ + E
Sbjct: 810 QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862
Query: 978 KVKNLTEEMAGLDETIAKLTKEKKALQE--AHQQTLDDLQ-AEEDKVNTLTKAKI-KLEQ 1033
+ +++ A L + K KE K ++E ++ ++DLQ +E + +LT+A + KL++
Sbjct: 863 EALQKSQKEAELTRELEK-QKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQE 921
Query: 1034 QVDDLEGSLEQE---------KKIRMD-LERAKRKLEGDLKLAQESTMDI 1073
+ D LE+E + + D ++ R +E L + E + ++
Sbjct: 922 RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSEL 971
Score = 34.7 bits (78), Expect = 0.93
Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 11/117 (9%)
Query: 1516 LTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1575
L E+ + K+ E E+ KK+ E+E+ E + EAE + EE R Q EL ++
Sbjct: 812 LAEKREQEEKKKQEEEE-KKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK- 867
Query: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1632
+K AE E+++ K N ++ E ++ L+ EI D R+K++ E L E +Q
Sbjct: 868 -SQKEAELTRELEKQKENK-QVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 478 bits (1231), Expect = e-134
Identities = 323/928 (34%), Positives = 491/928 (52%), Gaps = 76/928 (8%)
Query: 79 PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAE 138
PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y+ E
Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117
Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198
+ Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176
Query: 199 IAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258
A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
Query: 259 GKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQ 318
G + A IE YLLEKSRV Q ER+YH+FY ++ D + L + DY +++
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDYNYLAM 283
Query: 319 GE-ITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAE 377
G IT D +E SA+++L FT E I KL A++H GN++++ + E
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENL-- 341
Query: 378 PDGTEVADK-----AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAK 432
D EV AA L +N DL+ L + E V+ + +Q + A K
Sbjct: 342 -DACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVK 400
Query: 433 AVYDKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNE 486
+Y ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF NE
Sbjct: 401 GIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANE 459
Query: 487 KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKA 546
LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FPK
Sbjct: 460 HLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKG 519
Query: 547 TDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNE 606
TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L+
Sbjct: 520 TDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
Query: 607 TVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNL 666
++ L S K + +F +A+ G + K+ T+S+ F+ +L LM L
Sbjct: 576 DIIQLVHSSRNKFIKQIF------QADVAMGAETRKRS----PTLSSQFKRSLELLMRTL 625
Query: 667 RSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRY 726
+ P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +RY
Sbjct: 626 GACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERY 685
Query: 727 KVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLA 786
+VL P + D + +++ ++ H ++ G TK+F K LLE RD+ +
Sbjct: 686 RVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAIT 745
Query: 787 QLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKL-YFKIKPLLK 845
+ Q + RGF R + K+ + + IQ + R K++ M+L + +++ L +
Sbjct: 746 DRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHR 802
Query: 846 SAETEKEMANMKEEFEKTKEELAKTEAK-RKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
S + + +++ ++ + + +A+ R L K + + L VQA A +
Sbjct: 803 SRK-------LHQQYRLARQRIIQFQARCRAYLVRK---AFRHRLWAVLTVQAYARGM-- 850
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDI 958
R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L ++
Sbjct: 851 IARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARED 908
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEM 986
+ EL KEK A K K L E+M
Sbjct: 909 AEREL------KEKEAARRK-KELLEQM 929
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 478 bits (1231), Expect = e-134
Identities = 323/928 (34%), Positives = 491/928 (52%), Gaps = 76/928 (8%)
Query: 79 PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAE 138
PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y+ E
Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117
Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198
+ Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176
Query: 199 IAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258
A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
Query: 259 GKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQ 318
G + A IE YLLEKSRV Q ER+YH+FY ++ D + L + DY +++
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDYNYLAM 283
Query: 319 GE-ITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAE 377
G IT D +E SA+++L FT E I KL A++H GN++++ + E
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENL-- 341
Query: 378 PDGTEVADK-----AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAK 432
D EV AA L +N DL+ L + E V+ + +Q + A K
Sbjct: 342 -DACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVK 400
Query: 433 AVYDKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNE 486
+Y ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF NE
Sbjct: 401 GIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANE 459
Query: 487 KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKA 546
LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FPK
Sbjct: 460 HLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKG 519
Query: 547 TDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNE 606
TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L+
Sbjct: 520 TDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
Query: 607 TVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNL 666
++ L S K + +F +A+ G + K+ T+S+ F+ +L LM L
Sbjct: 576 DIIQLVHSSRNKFIKQIF------QADVAMGAETRKRS----PTLSSQFKRSLELLMRTL 625
Query: 667 RSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRY 726
+ P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +RY
Sbjct: 626 GACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERY 685
Query: 727 KVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLA 786
+VL P + D + +++ ++ H ++ G TK+F K LLE RD+ +
Sbjct: 686 RVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAIT 745
Query: 787 QLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKL-YFKIKPLLK 845
+ Q + RGF R + K+ + + IQ + R K++ M+L + +++ L +
Sbjct: 746 DRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHR 802
Query: 846 SAETEKEMANMKEEFEKTKEELAKTEAK-RKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
S + + +++ ++ + + +A+ R L K + + L VQA A +
Sbjct: 803 SRK-------LHQQYRLARQRIIQFQARCRAYLVRK---AFRHRLWAVLTVQAYARGM-- 850
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDI 958
R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L ++
Sbjct: 851 IARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARED 908
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEM 986
+ EL KEK A K K L E+M
Sbjct: 909 AEREL------KEKEAARRK-KELLEQM 929
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 478 bits (1231), Expect = e-134
Identities = 323/928 (34%), Positives = 491/928 (52%), Gaps = 76/928 (8%)
Query: 79 PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAE 138
PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y+ E
Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117
Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198
+ Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176
Query: 199 IAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258
A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
Query: 259 GKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQ 318
G + A IE YLLEKSRV Q ER+YH+FY ++ D + L + DY +++
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDYNYLAM 283
Query: 319 GE-ITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAE 377
G IT D +E SA+++L FT E I KL A++H GN++++ + E
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENL-- 341
Query: 378 PDGTEVADK-----AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAK 432
D EV AA L +N DL+ L + E V+ + +Q + A K
Sbjct: 342 -DACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVK 400
Query: 433 AVYDKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNE 486
+Y ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF NE
Sbjct: 401 GIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANE 459
Query: 487 KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKA 546
LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FPK
Sbjct: 460 HLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKG 519
Query: 547 TDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNE 606
TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L+
Sbjct: 520 TDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
Query: 607 TVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNL 666
++ L S K + +F +A+ G + K+ T+S+ F+ +L LM L
Sbjct: 576 DIIQLVHSSRNKFIKQIF------QADVAMGAETRKRS----PTLSSQFKRSLELLMRTL 625
Query: 667 RSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRY 726
+ P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +RY
Sbjct: 626 GACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERY 685
Query: 727 KVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLA 786
+VL P + D + +++ ++ H ++ G TK+F K LLE RD+ +
Sbjct: 686 RVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAIT 745
Query: 787 QLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKL-YFKIKPLLK 845
+ Q + RGF R + K+ + + IQ + R K++ M+L + +++ L +
Sbjct: 746 DRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHR 802
Query: 846 SAETEKEMANMKEEFEKTKEELAKTEAK-RKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
S + + +++ ++ + + +A+ R L K + + L VQA A +
Sbjct: 803 SRK-------LHQQYRLARQRIIQFQARCRAYLVRK---AFRHRLWAVLTVQAYARGM-- 850
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDI 958
R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L ++
Sbjct: 851 IARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARED 908
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEM 986
+ EL KEK A K K L E+M
Sbjct: 909 AEREL------KEKEAARRK-KELLEQM 929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,266,571
Number of Sequences: 37866
Number of extensions: 2886599
Number of successful extensions: 64631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 833
Number of HSP's successfully gapped in prelim test: 1572
Number of HSP's that attempted gapping in prelim test: 14102
Number of HSP's gapped (non-prelim): 16738
length of query: 1939
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1822
effective length of database: 13,817,196
effective search space: 25174931112
effective search space used: 25174931112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.