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Search of human proteins with 115496169
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
(1935 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 3745 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 3494 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3150 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3137 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3137 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3115 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3114 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3040 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 2977 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2678 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2401 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1445 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1445 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1443 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1443 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1428 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1422 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1318 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1316 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1306 0.0
gi|153945715 myosin VC [Homo sapiens] 611 e-174
gi|215982791 myosin VA isoform 1 [Homo sapiens] 601 e-171
gi|215982794 myosin VA isoform 2 [Homo sapiens] 600 e-171
gi|122937345 myosin VB [Homo sapiens] 578 e-164
gi|28416946 myosin 18A isoform a [Homo sapiens] 518 e-146
gi|42794779 myosin 18A isoform b [Homo sapiens] 515 e-145
gi|154354979 myosin X [Homo sapiens] 489 e-138
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 483 e-136
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 483 e-136
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 483 e-136
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 3745 bits (9712), Expect = 0.0
Identities = 1935/1935 (100%), Positives = 1935/1935 (100%)
Query: 1 MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVT 60
MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVT
Sbjct: 1 MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVT 60
Query: 61 AETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGL 120
AETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGL
Sbjct: 61 AETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGL 120
Query: 121 FCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
FCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES
Sbjct: 121 FCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
Query: 181 GAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDN 240
GAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDN
Sbjct: 181 GAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDN 240
Query: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM
Sbjct: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
Query: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG
Sbjct: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
Query: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV
Sbjct: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
Query: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF
Sbjct: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
Query: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF
Sbjct: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
Query: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP
Sbjct: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMT 660
LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMT
Sbjct: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMT 660
Query: 661 NLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQ 720
NLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQ
Sbjct: 661 NLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQ 720
Query: 721 RYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDER 780
RYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDER
Sbjct: 721 RYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDER 780
Query: 781 LSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLL 840
LSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLL
Sbjct: 781 LSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLL 840
Query: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELT 960
AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELT
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELT 960
Query: 961 LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTL 1020
LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTL
Sbjct: 961 LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLS 1140
KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLS
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLS 1140
Query: 1141 RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSV 1200
RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSV
Sbjct: 1141 RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSV 1200
Query: 1201 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 1260
AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR
Sbjct: 1201 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 1260
Query: 1261 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLE 1320
SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLE
Sbjct: 1261 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLE 1320
Query: 1321 EEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAI 1380
EEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAI
Sbjct: 1321 EEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAI 1380
Query: 1381 QRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAA 1440
QRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAA
Sbjct: 1381 QRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAA 1440
Query: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 1561 AQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEG 1620
AQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEG
Sbjct: 1561 AQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEG 1620
Query: 1621 DLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL 1680
DLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL
Sbjct: 1621 DLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL 1680
Query: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEA 1800
VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEA
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEA 1800
Query: 1801 EQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKN 1860
EQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKN
Sbjct: 1801 EQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKN 1860
Query: 1861 LLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1920
LLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL
Sbjct: 1861 LLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1920
Query: 1921 RAKSRDIGTKGLNEE 1935
RAKSRDIGTKGLNEE
Sbjct: 1921 RAKSRDIGTKGLNEE 1935
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 3494 bits (9060), Expect = 0.0
Identities = 1796/1932 (92%), Positives = 1865/1932 (96%), Gaps = 2/1932 (0%)
Query: 1 MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVT 60
M D++MA FGAAA YLRKSEKERLEAQTRPFD++ + FVPDDK+EFVKAKI+SREGGKV
Sbjct: 1 MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVI 60
Query: 61 AETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGL 120
AETE GKTVTVKEDQV+QQNPPKFDKIEDMAMLTFLHEPAVL+NLK+RY +WMIYTYSGL
Sbjct: 61 AETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGL 120
Query: 121 FCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
FCVTVNPYKWLPVY EVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES
Sbjct: 121 FCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
Query: 181 GAGKTVNTKRVIQYFAVIAAIGDRSKKDQS-PGKGTLEDQIIQANPALEAFGNAKTVRND 239
GAGKTVNTKRVIQYFA IAAIGDR KKD + KGTLEDQIIQANPALEAFGNAKTVRND
Sbjct: 181 GAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRND 240
Query: 240 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLD 299
NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAER+YHIFYQILSNKKPELLD
Sbjct: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
Query: 300 MLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHF 359
MLL+TNNPYDYAF+SQGE +VASIDD+EELMATD+AFDVLGFTSEEK +YKLTGAIMH+
Sbjct: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
Query: 360 GNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQ 419
GNMKFK KQREEQAEPDGTE+ADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQ+VQQ
Sbjct: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
Query: 420 VIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 479
V Y+ GALAKAVYE+MFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN
Sbjct: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
Query: 480 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 539
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM
Sbjct: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
Query: 540 FPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKD 599
FPKATDMTFKAKL+DNHLGKS NFQKPRNIKGK EAHFSLIHYAG VDYNI+GWL+KNKD
Sbjct: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
Query: 600 PLNETVVGLYQKSSLKLLSTLFANYAGADAPIE-KGKGKAKKGSSFQTVSALHRENLNKL 658
PLNETVV LYQKSSLKL++TLF++YA AD K KG KKGSSFQTVSALHRENLNKL
Sbjct: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
Query: 659 MTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 718
MTNLR+THPHFVRCIIPNE K+PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF
Sbjct: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
Query: 719 RQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 778
RQRYRILNP AIPEGQFIDSRKG EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD
Sbjct: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
Query: 779 ERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKP 838
ERLSRIITR+QAQ+RG L R+E+KK++ERRD+LLVIQWNIRAFMGVKNWPWMKLYFKIKP
Sbjct: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
Query: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
LLKSAE EKEMA+MKEEF R+KE LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL
Sbjct: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
Query: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELK+DIDDLE
Sbjct: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQ EEDKVN
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
Query: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
+L+K+KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK QL+E
Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 1079 RLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD 1138
+LKKK+F++N N++IEDEQ L QLQKKLKE QARIEELEEELEAERTARAKVEKLRSD
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
Query: 1139 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1198
LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD
Sbjct: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
Query: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK+ RTLEDQ NE
Sbjct: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
Query: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQ 1318
+R K EE QRS+ND T+QRAKLQTENGEL+RQL+EKEALISQLTRGKL+YTQQ+EDLKRQ
Sbjct: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
Query: 1319 LEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378
LEEE KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD
Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
Query: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1438
AIQRTEELEEAKKKLAQRLQ+AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA
Sbjct: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
Query: 1439 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1498
AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF
Sbjct: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
Query: 1499 KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKI 1558
KRENKNLQEEISDLTEQLG GK +HELEKVRKQLE EK+ELQSALEEAEASLEHEEGKI
Sbjct: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
Query: 1559 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM 1618
LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH RVVDSLQTSLDAETRSRNE LRVKKKM
Sbjct: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
Query: 1619 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1678
EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN
Sbjct: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 1679 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ 1738
NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKM++DL+QLQ
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
Query: 1739 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
+EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 1799 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 1858
EAEQIALKGGKKQLQKLEARVRELE ELEAEQKRNAESVKGMRKSERRIKELTYQTEED+
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 1859 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1918
KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN
Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 1919 KLRAKSRDIGTK 1930
KLRAKSRDIG K
Sbjct: 1921 KLRAKSRDIGAK 1932
Score = 66.2 bits (160), Expect = 3e-10
Identities = 85/385 (22%), Positives = 169/385 (43%), Gaps = 27/385 (7%)
Query: 755 QYKFGHTKVFFKAGLLGLLEEMRDERLS--RII----TRIQAQSRGVLARMEYKKLLERR 808
Q +F K + L EEM + + R++ T + A++R + KK +E
Sbjct: 1564 QLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623
Query: 809 DSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEA 868
+ + IQ + M + +K ++ LLK + + + A + LKE + E
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVK---SLQSLLKDTQIQLDDAVRAND--DLKENIAIVER 1678
Query: 869 RRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD-------QLIKNKIQLEAKVKE 921
R L+ ++ L + + + L + ER LI K ++E+ + +
Sbjct: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
Query: 922 MNERLED--EEEMNAELTAKKRKLEDE--CSELKRDIDDLELTLAKVEKEKHATENKVKN 977
+ +E+ +E NAE AKK + ELK++ D T A +E+ K E +K+
Sbjct: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQD----TSAHLERMKKNMEQTIKD 1794
Query: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALD-DLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
L + ++I K K++ EA + L+ +L+AE+ + K K E+++ +L
Sbjct: 1795 LQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTY 1854
Query: 1037 SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIED 1096
E++KK + L+ KL+ +K + + E + +K EL+ R +
Sbjct: 1855 QTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI 1914
Query: 1097 EQALGSQLQKKLKELQARIEELEEE 1121
++ ++L+ K +++ A+ + +EE
Sbjct: 1915 AESQVNKLRAKSRDIGAKQKMHDEE 1939
Score = 36.2 bits (82), Expect = 0.32
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 19/134 (14%)
Query: 1809 KKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL--RLQD 1866
K+ L+K EAR +ELE ++ + + E+ +L Q E+D N R
Sbjct: 862 KETLEKSEARRKELEEKMVSLLQ------------EKNDLQLQVQAEQDNLNDAEERCDQ 909
Query: 1867 LV-DKLQL--KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923
L+ +K+QL KVK + E+ EE +K RK++ E E ++ D E + K+ +
Sbjct: 910 LIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 969
Query: 1924 --SRDIGTKGLNEE 1935
+ + K L EE
Sbjct: 970 KHATENKVKNLTEE 983
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 3150 bits (8166), Expect = 0.0
Identities = 1573/1936 (81%), Positives = 1767/1936 (91%), Gaps = 3/1936 (0%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
DSEMA+FG AAP+LRKSE+ER+EAQ +PFD K VFV D K+ FVKA + SREGGKVTA+
Sbjct: 4 DSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAK 63
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
TE G TVTVK+DQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 64 TEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 124 VTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 184 GKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER YHIFYQI+SNKKP+L++M
Sbjct: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEM 303
Query: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
LLIT NPYDYAF+SQGE TV SIDD EELMATD+A ++LGFTS+E+ S+YKLTGA+MH+G
Sbjct: 304 LLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYG 363
Query: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
NMKFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ VQQV
Sbjct: 364 NMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 423
Query: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
A GALAKAVY++MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 424 YNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
Query: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
Query: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
PKATD +FK KL++ HLGKS NFQKP+ KGKPEAHFSLIHYAG VDYNI GWL KNKDP
Sbjct: 544 PKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDP 603
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGK-GKAKKGSSFQTVSALHRENLNKLM 659
LNETVVGLYQKS++K L+ LF GA+A GK G KKGSSFQTVSAL RENLNKLM
Sbjct: 604 LNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLM 663
Query: 660 TNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 719
TNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF+
Sbjct: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
Query: 720 QRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 779
QRY++LN +AIPEGQFIDS+K +EKLL S+DIDH QYKFGHTKVFFKAGLLGLLEEMRDE
Sbjct: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDE 783
Query: 780 RLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPL 839
+L+++ITR QA RG LAR+EY+K++ERR+S+ IQ+N+RAFM VK+WPWMKLYFKIKPL
Sbjct: 784 KLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPL 843
Query: 840 LKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLA 899
LKSAE EKEMA+MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D+LA
Sbjct: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLA 903
Query: 900 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLEL 959
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDLEL
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
Query: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
TLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQAEEDKVNT
Sbjct: 964 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1023
Query: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
LTKAK+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDKQQLDE+
Sbjct: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEK 1083
Query: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
LKKK+FE++ L ++IEDEQALG QLQKK+KELQARIEELEEE+EAER +RAK EK RSDL
Sbjct: 1084 LKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
Query: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
SRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHADS
Sbjct: 1144 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1203
Query: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
VAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SNME + KAK NLEKMCR LEDQ++E
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 1263
Query: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
++K EE QR +NDLT+QRA+LQTE+GE SRQLDEK+ L+SQL+RGK +TQQ+E+LKRQL
Sbjct: 1264 KTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQL 1323
Query: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
EEE+KAK+ALAHALQS+RHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETDA
Sbjct: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439
IQRTEELEEAKKKLAQRLQ+AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NAA
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAAC 1443
Query: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499
AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKE+RSLSTELFK+KNAYEESL+ LET K
Sbjct: 1444 AALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLK 1503
Query: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559
RENKNLQ+EISDLTEQ+ GK IHELEK++KQ+E EK ELQ+ALEEAEASLEHEEGKIL
Sbjct: 1504 RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKIL 1563
Query: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619
R QLE NQ+K+E++RK+AEKDEE++Q KRNH+R+V+S+Q++LDAE RSRN+A+R+KKKME
Sbjct: 1564 RIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME 1623
Query: 1620 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1679
GDLNEMEIQL+HANRMAAEA + ++ Q++LKDTQ+ LDDA+R+ +DLKE +A+VERR N
Sbjct: 1624 GDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRAN 1683
Query: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQT 1739
LLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+Q
Sbjct: 1684 LLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743
Query: 1740 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1799
E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDE
Sbjct: 1744 EMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803
Query: 1800 AEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRK 1859
AEQ+ALKGGKKQ+QKLEARVRELE E+E+EQKRN E+VKG+RK ER++KELTYQTEEDRK
Sbjct: 1804 AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRK 1863
Query: 1860 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1919
N+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFR++QHEL+EAEERADIAESQVNK
Sbjct: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNK 1923
Query: 1920 LRAKSRDIGTKGLNEE 1935
LR KSR++ TK ++EE
Sbjct: 1924 LRVKSREVHTKIISEE 1939
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3137 bits (8133), Expect = 0.0
Identities = 1571/1938 (81%), Positives = 1769/1938 (91%), Gaps = 5/1938 (0%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
DSE+AVFG AAP+LRKSE+ER+EAQ RPFD K VFV + K+ FVK I SREGGKVT +
Sbjct: 4 DSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK 63
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
TE G T+TVK+DQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 64 TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY PEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 124 VTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 184 GKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER YHIFYQI SNKKPEL++M
Sbjct: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEM 303
Query: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
LLIT NPYDY F+SQGE +VASIDD EELMATD+A D+LGFT+EEK S+YKLTGA+MH+G
Sbjct: 304 LLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYG 363
Query: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
N+KFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ V+QV
Sbjct: 364 NLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQV 423
Query: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
A GALAKAVYE+MF WMV RIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 424 SNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
Query: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
Query: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
PKATD +FK KL+D HLGKSANFQKP+ +KGK EAHF+LIHYAG+VDYNI GWL+KNKDP
Sbjct: 544 PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDP 603
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKG---KGKAKKGSSFQTVSALHRENLNK 657
LNETVVGLYQKS++K L+ LF+ A+ G KG KKGSSFQTVSAL RENLNK
Sbjct: 604 LNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNK 663
Query: 658 LMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGD 717
LMTNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY D
Sbjct: 664 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 723
Query: 718 FRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMR 777
F+QRY++LN +AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMR
Sbjct: 724 FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 783
Query: 778 DERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIK 837
D++L+++ITR QA+ RG LAR+EY++++ERR+++ IQ+NIR+FM VK+WPWMKL+FKIK
Sbjct: 784 DDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIK 843
Query: 838 PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDN 897
PLLKSAE EKEMA+MKEEF ++K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE +
Sbjct: 844 PLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEG 903
Query: 898 LADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDL 957
LADAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDL
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017
ELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQAEEDKV
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077
NTLTKAK+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+KQQLD
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083
Query: 1078 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 1137
E+LKKK+FE++ L ++IEDEQALG QLQKK+KELQARIEELEEE+EAER +RAK EK RS
Sbjct: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
Query: 1138 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1197
DLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHA
Sbjct: 1144 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
Query: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257
DSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEKMCRTLEDQ++
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 1258 EHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKR 1317
E +SK EE QR +NDLT+QR +LQTE+GE SRQLDEKEAL+SQL+RGK +TQQ+E+LKR
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR 1323
Query: 1318 QLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYET 1377
QLEEE+KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYET
Sbjct: 1324 QLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYET 1383
Query: 1378 DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1437
DAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NA
Sbjct: 1384 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 1438 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
A AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LET
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557
KRENKNLQ+EISDLTEQ+ GK IHELEK++KQ+E EK ELQ+ALEEAEASLEHEEGK
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
Query: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617
ILR QLE NQ+K+E++RK+AEKDEE++Q KRNH+R+V+S+Q++LDAE RSRN+A+R+KKK
Sbjct: 1564 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1623
Query: 1618 MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1677
MEGDLNEMEIQL+HANRMAAEA + ++ Q +LKDTQI LDDA+R+ +DLKE +A+VERR
Sbjct: 1624 MEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERR 1683
Query: 1678 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQL 1737
NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+
Sbjct: 1684 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 1738 QTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797
Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RL
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Query: 1798 DEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEED 1857
DEAEQ+ALKGGKKQ+QKLEARVRELE E+E+EQKRNAE+VKG+RK ERR+KELTYQTEED
Sbjct: 1804 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED 1863
Query: 1858 RKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV 1917
RKN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQV
Sbjct: 1864 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
Query: 1918 NKLRAKSRDIGTKGLNEE 1935
NKLR KSR++ TK ++EE
Sbjct: 1924 NKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3137 bits (8133), Expect = 0.0
Identities = 1571/1938 (81%), Positives = 1769/1938 (91%), Gaps = 5/1938 (0%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
DSE+AVFG AAP+LRKSE+ER+EAQ RPFD K VFV + K+ FVK I SREGGKVT +
Sbjct: 4 DSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK 63
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
TE G T+TVK+DQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 64 TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY PEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 124 VTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 184 GKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER YHIFYQI SNKKPEL++M
Sbjct: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEM 303
Query: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
LLIT NPYDY F+SQGE +VASIDD EELMATD+A D+LGFT+EEK S+YKLTGA+MH+G
Sbjct: 304 LLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYG 363
Query: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
N+KFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ V+QV
Sbjct: 364 NLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQV 423
Query: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
A GALAKAVYE+MF WMV RIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 424 SNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
Query: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
Query: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
PKATD +FK KL+D HLGKSANFQKP+ +KGK EAHF+LIHYAG+VDYNI GWL+KNKDP
Sbjct: 544 PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDP 603
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKG---KGKAKKGSSFQTVSALHRENLNK 657
LNETVVGLYQKS++K L+ LF+ A+ G KG KKGSSFQTVSAL RENLNK
Sbjct: 604 LNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNK 663
Query: 658 LMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGD 717
LMTNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY D
Sbjct: 664 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 723
Query: 718 FRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMR 777
F+QRY++LN +AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMR
Sbjct: 724 FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 783
Query: 778 DERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIK 837
D++L+++ITR QA+ RG LAR+EY++++ERR+++ IQ+NIR+FM VK+WPWMKL+FKIK
Sbjct: 784 DDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIK 843
Query: 838 PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDN 897
PLLKSAE EKEMA+MKEEF ++K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE +
Sbjct: 844 PLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEG 903
Query: 898 LADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDL 957
LADAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDL
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017
ELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQAEEDKV
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077
NTLTKAK+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+KQQLD
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083
Query: 1078 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 1137
E+LKKK+FE++ L ++IEDEQALG QLQKK+KELQARIEELEEE+EAER +RAK EK RS
Sbjct: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
Query: 1138 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1197
DLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHA
Sbjct: 1144 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
Query: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257
DSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEKMCRTLEDQ++
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 1258 EHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKR 1317
E +SK EE QR +NDLT+QR +LQTE+GE SRQLDEKEAL+SQL+RGK +TQQ+E+LKR
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR 1323
Query: 1318 QLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYET 1377
QLEEE+KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYET
Sbjct: 1324 QLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYET 1383
Query: 1378 DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1437
DAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NA
Sbjct: 1384 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 1438 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
A AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LET
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557
KRENKNLQ+EISDLTEQ+ GK IHELEK++KQ+E EK ELQ+ALEEAEASLEHEEGK
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
Query: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617
ILR QLE NQ+K+E++RK+AEKDEE++Q KRNH+R+V+S+Q++LDAE RSRN+A+R+KKK
Sbjct: 1564 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1623
Query: 1618 MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1677
MEGDLNEMEIQL+HANRMAAEA + ++ Q +LKDTQI LDDA+R+ +DLKE +A+VERR
Sbjct: 1624 MEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERR 1683
Query: 1678 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQL 1737
NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+
Sbjct: 1684 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 1738 QTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797
Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RL
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Query: 1798 DEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEED 1857
DEAEQ+ALKGGKKQ+QKLEARVRELE E+E+EQKRNAE+VKG+RK ERR+KELTYQTEED
Sbjct: 1804 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED 1863
Query: 1858 RKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV 1917
RKN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQV
Sbjct: 1864 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
Query: 1918 NKLRAKSRDIGTKGLNEE 1935
NKLR KSR++ TK ++EE
Sbjct: 1924 NKLRVKSREVHTKVISEE 1941
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 3115 bits (8077), Expect = 0.0
Identities = 1564/1936 (80%), Positives = 1757/1936 (90%), Gaps = 3/1936 (0%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
DSEMA+FG AAP+LRKSEKER+EAQ +PFD K VFV D K+ +VKA + SREGGKVTA+
Sbjct: 4 DSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAK 63
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
TE G TVTVKEDQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 64 TEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY PEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 124 VTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 184 GKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
SSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQLKAER YHIFYQILSNKKPEL++M
Sbjct: 244 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEM 303
Query: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
LLIT NPYD+AF+SQGE TV SIDD EELMATD+A D+LGFT++EK ++YKLTGA+MH+G
Sbjct: 304 LLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYG 363
Query: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
NMKFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNE+VTKGQ VQQV
Sbjct: 364 NMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQV 423
Query: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
A GALAKA+YE+MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 424 YNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
Query: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
TNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
Query: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
PKATD +FK KL++ HLGKS NFQKP+ KGKPEAHFSL+HYAG VDYNI GWL KNKDP
Sbjct: 544 PKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDP 603
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGK-GKAKKGSSFQTVSALHRENLNKLM 659
LNETVVGLYQKS++K L+ LF+ A+A GK G KKGSSFQTVSAL RENLNKLM
Sbjct: 604 LNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLM 663
Query: 660 TNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 719
TNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF+
Sbjct: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
Query: 720 QRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 779
QRY++LN +AIPEGQFIDS+K +EKLL S++IDH QYKFGHTKVFFKAGLLG LEEMRDE
Sbjct: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDE 783
Query: 780 RLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPL 839
+L+++ITR QA RG L R+E++K++ERR+S+ IQ+NIRAFM VK+WPWMKLYFKIKPL
Sbjct: 784 KLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPL 843
Query: 840 LKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLA 899
LKSAE EKEMA+MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D LA
Sbjct: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALA 903
Query: 900 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLEL 959
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDLEL
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
Query: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
TLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDKVNT
Sbjct: 964 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNT 1023
Query: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
LTKAK KLEQQVDDLEGSLEQEKK+ MDLERAKRKLEGDLKL QES MD ENDKQQL+E+
Sbjct: 1024 LTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEK 1083
Query: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
LKKK+FE++ L +IEDEQAL QLQKK+KELQARIEELEEE+EAER +RAK EK RSDL
Sbjct: 1084 LKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
Query: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
SRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEE+TLQHEATAAALRKKHADS
Sbjct: 1144 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADS 1203
Query: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
VAELGEQID+LQRVKQKLEKEKSE K+E++D+ SNME + KAKAN EKMCRTLEDQ++E
Sbjct: 1204 VAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263
Query: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
++K EE QR +N+L++Q+A+L TE+GE SRQLDEK+A++SQL+RGK +TQQ+E+LKRQL
Sbjct: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
Query: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
EEE KAK+ LAHALQSARHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETDA
Sbjct: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
Query: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439
IQRTEELEEAKKKLAQRLQ+AEE VEAVN+KC+SLEKTK RLQNE+EDLM+DVERSNAA
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAAC 1443
Query: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499
ALDKKQRNFDK+LAEWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KNAYEESL+HLET K
Sbjct: 1444 IALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLK 1503
Query: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559
RENKNLQ+EISDLTEQ+ GK IHELEKV+KQL+ EK ELQ++LEEAEASLEHEEGKIL
Sbjct: 1504 RENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKIL 1563
Query: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619
R QLE NQ+K+EI+RK+AEKDEE++Q KRNHLRVV+S+Q++LDAE RSRN+ALR+KKKME
Sbjct: 1564 RIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKME 1623
Query: 1620 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1679
GDLNEMEIQL+HANR AAEA + +++ Q +LKDTQ+ LDDA+R DDLKE +A+VERR N
Sbjct: 1624 GDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRAN 1683
Query: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQT 1739
L+QAE+EELRA +E+TER RK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+Q
Sbjct: 1684 LMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743
Query: 1740 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1799
E+E+ VQE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RLDE
Sbjct: 1744 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDE 1803
Query: 1800 AEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRK 1859
AEQ+ALKGGKKQ+QKLEARVRELE+E+E+EQK N E+VKG+RK ERR+KELTYQTEEDRK
Sbjct: 1804 AEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRK 1863
Query: 1860 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1919
N+LRLQDLVDKLQ KVKAYKRQAEEAEEQ+N NL+KFRK+QHEL+EA+ERADIAESQVNK
Sbjct: 1864 NILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNK 1923
Query: 1920 LRAKSRDIGTKGLNEE 1935
LR KSR++ TK ++EE
Sbjct: 1924 LRVKSREVHTKVISEE 1939
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 3114 bits (8074), Expect = 0.0
Identities = 1559/1928 (80%), Positives = 1750/1928 (90%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
D+EMAVFG AAPYLRKSEKER+EAQ +PFD K VFV + K+ +VK+ I S+EGGKVT +
Sbjct: 6 DAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVK 65
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
TE G T+TV+EDQV NPPK+DKIEDMAM+T LHEP VLYNLK+RY +WMIYTYSGLFC
Sbjct: 66 TEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFC 125
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY PEVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 126 VTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 185
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSS 242
GKTVNTKRVIQYFA IA G++ K + +GTLEDQII ANP LEAFGNAKTVRNDNSS
Sbjct: 186 GKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSS 245
Query: 243 RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLL 302
RFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER YHIFYQI SNKKP+L++MLL
Sbjct: 246 RFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLL 305
Query: 303 ITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNM 362
IT NPYDYAF+SQGE TV SIDD EELMATD+A D+LGFT EEK S+YKLTGA+MH+GNM
Sbjct: 306 ITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNM 365
Query: 363 KFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIY 422
KFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ VQQV
Sbjct: 366 KFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYN 425
Query: 423 ATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN 482
A GALAKAVYE+MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINFTN
Sbjct: 426 AVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTN 485
Query: 483 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPK 542
EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKP+GI SILEEECMFPK
Sbjct: 486 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPK 545
Query: 543 ATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLN 602
ATD +FK KL+D HLGKSANFQKP+ +KGK EAHFSLIHYAG VDYNI GWL KNKDPLN
Sbjct: 546 ATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLN 605
Query: 603 ETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNL 662
+TVVGLYQKS++K L++LF+ YA A+A KG KKGSSFQTVSAL RENLNKLMTNL
Sbjct: 606 DTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNL 665
Query: 663 RSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRY 722
RSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILYGDF+QRY
Sbjct: 666 RSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRY 725
Query: 723 RILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 782
++LN +AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMRDE+L+
Sbjct: 726 KVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLA 785
Query: 783 RIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 842
+IITR QA RG L R+EY+K+L+RR++L IQ+N+RAFM VK+WPWMKL+FKIKPLLKS
Sbjct: 786 QIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKS 845
Query: 843 AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
AE EKEMA+MKEEF + K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQ+E D+LADAE
Sbjct: 846 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAE 905
Query: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
ERC+QLIKNKIQLEAK+KE+ ER E+EEE+NAELTAKKRKLEDECSELK+DIDDLELTLA
Sbjct: 906 ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 963 KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTK 1022
KVEKEKHATENKVKNLTEEMAGLDE IAKL+KEKKALQE HQQ LDDLQAEEDKVN LTK
Sbjct: 966 KVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTK 1025
Query: 1023 AKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKK 1082
AK KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDKQQLDE+L+K
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK 1085
Query: 1083 KDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRE 1142
K+FE++ L ++IEDEQA+ QLQKK+KELQARIEEL EE+EAER +RAK EK RSDLSRE
Sbjct: 1086 KEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRE 1145
Query: 1143 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202
LEEISERLEEAGGATS Q+E+NKKREAEFQK+RRDLEEATLQHEA AALRKKHADS+AE
Sbjct: 1146 LEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAE 1205
Query: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSK 1262
LGEQIDNLQRVKQKLEKEKSE K+E DD++SN E I KAK NLEKMCR+LEDQ++E ++K
Sbjct: 1206 LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK 1265
Query: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322
EE QR +NDLT+QRA+LQTE GE SRQLDEK+AL+SQL+R K TQQ+E+LK QLEEE
Sbjct: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325
Query: 1323 VKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDAIQR
Sbjct: 1326 TKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1385
Query: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
TEELEEAKKKLAQRLQEAEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVERSNAA AAL
Sbjct: 1386 TEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAAL 1445
Query: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN 1502
DKKQRNFDK+L+EWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KN YEESL+ LET +REN
Sbjct: 1446 DKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRREN 1505
Query: 1503 KNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQ 1562
KNLQ+EISDLTEQ+ GK IHELEK++KQ+E EK E+Q+ALEEAEASLEHEEGKILR Q
Sbjct: 1506 KNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQ 1565
Query: 1563 LEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDL 1622
LE NQ+K+E++RK+AEKDEE++Q KRNH RVV+++Q++LDAE RSRN+ALRVKKKMEGDL
Sbjct: 1566 LELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDL 1625
Query: 1623 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 1682
NEMEIQL+HANR+AAE+ + ++ Q +LK+TQ+ LDDA+R +DLKE +AIVERR NLLQ
Sbjct: 1626 NEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQ 1685
Query: 1683 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
AE+EEL A +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQLQ+EVE
Sbjct: 1686 AEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVE 1745
Query: 1743 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
E +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDEAEQ
Sbjct: 1746 EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1805
Query: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
+ALKGGKKQ+QKLEARVRELE E+E EQKRNAE+VKG+RK ERR+KELTYQTEEDRKN+L
Sbjct: 1806 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVL 1865
Query: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
RLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFRK+QHEL+EAEERADIAESQVNKLR
Sbjct: 1866 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRV 1925
Query: 1923 KSRDIGTK 1930
KSR++ TK
Sbjct: 1926 KSREVHTK 1933
Score = 180 bits (457), Expect = 1e-44
Identities = 194/872 (22%), Positives = 378/872 (43%), Gaps = 117/872 (13%)
Query: 831 KLYFKIKPLLKSAEREKEMA-----SMKEEFTRLKEALEKSEARR--------------K 871
K F+I L+ E E+ + +KE R++E E+ EA R +
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144
Query: 872 ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEE- 930
ELEE L + QV+ + A+ ++ L + +Q EA V + ++ D
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204
Query: 931 ---EMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-- 985
E L K+KLE E SELK + DDL + K K E ++L ++++ L
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKT 1264
Query: 986 -----DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQ 1040
+I LT ++ LQ + L ++ V+ L+++K QQ+++L+ LE+
Sbjct: 1265 KEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE 1324
Query: 1041 EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE-DEQA 1099
E K + L A + D L +E + + K +L L K + E+ + E D
Sbjct: 1325 ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ 1384
Query: 1100 LGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSV 1159
+L++ K+L R++E EE +EA A +EK + L E+E++ +E + A +
Sbjct: 1385 RTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAA 1444
Query: 1160 QIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEK 1219
+ + + + ++ EE + EA+ R + ++L ++ + L +
Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL-ETLRR 1503
Query: 1220 EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
E + E+ D+T + + K LEK+ + +E + E ++ EE + S+ + +
Sbjct: 1504 ENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
Query: 1280 LQTE----NGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKN-------- 1327
+Q E E+ R++ EK+ I QL R +T+ +E ++ L+ E++++N
Sbjct: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRN---HTRVVETMQSTLDAEIRSRNDALRVKKK 1620
Query: 1328 -----------------ALAHALQSARHDCDLLREQY-------EEETEAKAELQRVLSK 1363
A +L++ R+ +L+E + + K +L V +
Sbjct: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
Query: 1364 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423
AN A+ + T E+ E ++K Q L +A E V+ ++ + +SL TK +L+N
Sbjct: 1681 ANLLQAEIEELWAT-----LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEN 1735
Query: 1424 EIEDLMVDVE----------------------------RSNAAAAALDKKQRNFDKILAE 1455
++ L +VE + +A L++ ++N ++ + +
Sbjct: 1736 DVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1795
Query: 1456 WKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISDLT 1513
+ + +E+ Q L+ +K+ + L + +L+ E E + E K K+ + + +LT
Sbjct: 1796 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH-ERRVKELT 1854
Query: 1514 EQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE 1573
Q K + L+ + +L+A+ + EEAE K F +++ E+E
Sbjct: 1855 YQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSK-------FRKLQHELE 1907
Query: 1574 RKLAEKDEEMEQAKRNHLRVVD-SLQTSLDAE 1604
AE+ ++ +++ N LRV + T + AE
Sbjct: 1908 E--AEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 36.2 bits (82), Expect = 0.32
Identities = 38/169 (22%), Positives = 70/169 (41%), Gaps = 28/169 (16%)
Query: 1769 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA 1828
L K +T + MK+ ++T K +L K EA+ +ELE ++
Sbjct: 842 LLKSAETEKEMATMKEEFQKT-------------------KDELAKSEAKRKELEEKMVT 882
Query: 1829 EQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ 1888
K + ++ + + + E+ KN ++L+ K+K +AEE EE
Sbjct: 883 LLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE-------AKIKEVTERAEEEEEI 935
Query: 1889 ANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK--SRDIGTKGLNEE 1935
+K RK++ E E ++ D E + K+ + + + K L EE
Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 984
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 3040 bits (7882), Expect = 0.0
Identities = 1525/1924 (79%), Positives = 1728/1924 (89%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
D+EM VFG AAP+LRKSEKER+EAQ +PFD K FV D K+E+ K KI S + GKVT E
Sbjct: 4 DTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVE 63
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
TE +T+ VK + V NPPKFD+IEDMAMLT L+EPAVLYNLKDRY SWMIYTYSGLFC
Sbjct: 64 TEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFC 123
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY PEVV YRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 124 VTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSS 242
GKTVNTKRVIQYFA IAA GD +KK S KGTLEDQII ANP LEAFGNAKTVRNDNSS
Sbjct: 184 GKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSS 243
Query: 243 RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLL 302
RFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER YHIFYQILSNKKPEL+++LL
Sbjct: 244 RFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLL 303
Query: 303 ITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNM 362
IT NPYDY FISQGE VASIDDAEEL+ATD+A D+LGFT EEK+ +YKLTGA+MH+GNM
Sbjct: 304 ITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNM 363
Query: 363 KFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIY 422
KFK KQREEQAEPDGTE ADK+AYLMGLNS+DLLK LC PRVKVGNEYVTKGQ V QV +
Sbjct: 364 KFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHH 423
Query: 423 ATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN 482
A AL+K+VYE++F WMVTRIN L+TK PRQ+FIGVLDIAGFEIF++NS EQLCINFTN
Sbjct: 424 AVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTN 483
Query: 483 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPK 542
EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMFPK
Sbjct: 484 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPK 543
Query: 543 ATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLN 602
ATD +FK KL+D HLGKS NFQKP+ +KG+ EAHFSLIHYAG VDY++ GWL+KNKDPLN
Sbjct: 544 ATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLN 603
Query: 603 ETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNL 662
ETVVGLYQKSS +LL+ L+A +A ADA K K KKGSSFQTVSAL RENLNKLM+NL
Sbjct: 604 ETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNL 663
Query: 663 RSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRY 722
R+THPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFPNRILYGDF+QRY
Sbjct: 664 RTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRY 723
Query: 723 RILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 782
R+LN +AIPEGQFIDS+K EKLL+S+DIDH QYKFGHTKVFFKAGLLG LEEMRD+RL+
Sbjct: 724 RVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLA 783
Query: 783 RIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 842
++ITR QA RG L R+E++K+++RR+S+ IQ+NIR+FM VK+WPWMKL+FKIKPLLKS
Sbjct: 784 KLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKS 843
Query: 843 AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
AE EKEMA+MKEEF + K+ L KSEA+RKELEEK+V+L+QEKNDLQLQVQAE +NL DAE
Sbjct: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
Query: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
ERCDQLIK K QLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDLELTLA
Sbjct: 904 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963
Query: 963 KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTK 1022
KVEKEKHATENKVKNLTEE++GLDE IAKLT+EKKALQEAHQQALDDLQAEEDKVN+L K
Sbjct: 964 KVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNK 1023
Query: 1023 AKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKK 1082
K KLEQQV+DLE SLEQEKK+R+DLER KRKLEGDLKL QESI+DLENDKQQLDERLKK
Sbjct: 1024 TKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKK 1083
Query: 1083 KDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRE 1142
KDFE L +++EDEQ LG Q QKK+KELQARIEELEEE+EAER RAK EK RSD +RE
Sbjct: 1084 KDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARE 1143
Query: 1143 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202
LEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA AALRKKHADSVAE
Sbjct: 1144 LEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAE 1203
Query: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSK 1262
LGEQIDNLQRVKQKLEKEKSEFKLE+DD++S+ME + K+KANLEK+CRTLEDQ++E R K
Sbjct: 1204 LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK 1263
Query: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322
EE QRS+++LT+Q+++LQTE GELSRQL+EKE+++SQL+R K +TQQ E+LKRQLEEE
Sbjct: 1264 NEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEE 1323
Query: 1323 VKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDAIQR
Sbjct: 1324 NKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1383
Query: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
TEELEEAKKKLAQRLQ++EE VEAVNAKC+SLEKTK RLQ E+EDLMVDVER+N+ AAAL
Sbjct: 1384 TEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAAL 1443
Query: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN 1502
DKKQRNFDK+LAEWK K EESQ+ELE+S KE+RSLSTELFKLKNAYEE+L+ LET KREN
Sbjct: 1444 DKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKREN 1503
Query: 1503 KNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQ 1562
KNL++EI+DLTEQ+ +GKTIHELEK RKQ+E EK ++Q ALEEAEA+LEHEE KILR Q
Sbjct: 1504 KNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQ 1563
Query: 1563 LEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDL 1622
LE Q+K+EI+RK+AEKDEE+EQ KRN+ R V+++Q++LDAE RSRNEA+R+KKKMEGDL
Sbjct: 1564 LELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDL 1623
Query: 1623 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 1682
NE+EIQLSHANR AAE K ++S+Q LKDTQ+ LDDA+R +DLKE +AIVERR NLLQ
Sbjct: 1624 NEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQ 1683
Query: 1683 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
AE+EELRA +EQTER+RKLAEQEL++++ERVQLLH+QNTSLI+ KKK++ DL QLQ+EVE
Sbjct: 1684 AEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE 1743
Query: 1743 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
+A ++ RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDEAEQ
Sbjct: 1744 DASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1803
Query: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
+ALKGGKKQ+QKLE R+RELE ELE EQK+N ESVKG+RK ERR+KELTYQ+EEDRKN+L
Sbjct: 1804 LALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVL 1863
Query: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
RLQDLVDKLQ+KVK+YKRQAEEA+EQAN +L+KFRK QHEL+EAEERADIAESQVNKLRA
Sbjct: 1864 RLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRA 1923
Query: 1923 KSRD 1926
K+RD
Sbjct: 1924 KTRD 1927
Score = 155 bits (392), Expect = 4e-37
Identities = 158/788 (20%), Positives = 343/788 (43%), Gaps = 132/788 (16%)
Query: 855 EFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQ-DNLADAEERCDQLIKNKI 913
EF +L+ LE++ + E MV+ L++K+ + EQ DNL +++ + K K
Sbjct: 1171 EFLKLRRDLEEATLQH----EAMVAALRKKHADSVAELGEQIDNLQRVKQKLE---KEKS 1223
Query: 914 QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATEN 973
+ + ++ +++ +E + A L R LED+ SE + ++++ +L+++ +K +
Sbjct: 1224 EFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQT 1283
Query: 974 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDD 1033
+ L+ ++ + I+++L++ K+A + ++ L+ E N L A D
Sbjct: 1284 EAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDL 1343
Query: 1034 LEGSLEQEKKVRMDLERAKRKLEGDL-----KLTQESIM---DLENDKQQLDERLKKKDF 1085
L E+E++ + +L+RA K ++ K ++I +LE K++L +RL+ +
Sbjct: 1344 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEE 1403
Query: 1086 ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1145
++ A+NA+ + L+K + LQ +E+L ++E + A ++K + + + L E
Sbjct: 1404 QVEAVNAKC-------ASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 1146 ISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAA---LRKKHAD---S 1199
+ EE+ ++ ++ E K++ EEA Q E L ++ AD
Sbjct: 1457 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQ 1516
Query: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNME----------------------Q 1237
+AE G+ I L++ ++++E EK++ +L L++ + +E +
Sbjct: 1517 IAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRK 1576
Query: 1238 IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
I + +E++ R + + +S + RS N+ + K++ + E+ QL
Sbjct: 1577 IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQ 1636
Query: 1298 ISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE------ET 1351
++ + + QL+D + L++ ++ + L L +LL+ + EE +T
Sbjct: 1637 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 1352 EAKAELQ-----------RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400
E +L ++L N+ + + K ETD +Q E+E+A + ++A
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 1756
Query: 1401 EEAVE--AVNAK--------CSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQ---- 1446
++A+ A+ A+ + LE+ K L+ ++DL ++ + A KKQ
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 1447 -------------------------RNFDKILAEWKQKYEESQSEL-------------- 1467
R +++ + E + EE + +
Sbjct: 1817 ETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
Query: 1468 -------ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSG 1520
E + ++A + T+ K ++ EE+ E + + + L+ + D T SS
Sbjct: 1877 KSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFT----SSR 1932
Query: 1521 KTIHELEK 1528
+HE E+
Sbjct: 1933 MVVHESEE 1940
Score = 65.5 bits (158), Expect = 5e-10
Identities = 69/308 (22%), Positives = 133/308 (43%), Gaps = 58/308 (18%)
Query: 1636 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN-IAIVERRNNL---LQAELEELRAV 1691
+AE +K++ +++ + T+ +L + +L+E + +V+ +N+L +QAE E L
Sbjct: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDA 902
Query: 1692 VEQTERSRKLA---EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQEC 1748
E+ ++ K E ++ E +ER + N L +K+K++ + S+L+ ++++
Sbjct: 903 EERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 962
Query: 1749 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1804
E++ + EEL +T A L R KK ++ Q + DLQ D+ +
Sbjct: 963 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL- 1021
Query: 1805 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 1864
K KLE +V +LE+ LE E+K
Sbjct: 1022 ----NKTKSKLEQQVEDLESSLEQEKK--------------------------------- 1044
Query: 1865 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1924
L++ ++ KR+ E + A ++ + +LDE ++ D Q L++K
Sbjct: 1045 ------LRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQ---LQSKV 1095
Query: 1925 RDIGTKGL 1932
D T GL
Sbjct: 1096 EDEQTLGL 1103
Score = 37.4 bits (85), Expect = 0.14
Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 44/177 (24%)
Query: 1769 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA 1828
L K +T + MK+ ++T K +L K EA+ +ELE +L
Sbjct: 840 LLKSAETEKEMATMKEEFQKT-------------------KDELAKSEAKRKELEEKLVT 880
Query: 1829 -EQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL-------QLKVKAYKR 1880
Q++N +L Q + + +NLL ++ D+L + K+K
Sbjct: 881 LVQEKN---------------DLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTE 925
Query: 1881 QAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK--SRDIGTKGLNEE 1935
+AE+ EE +K RK++ E E ++ D E + K+ + + + K L EE
Sbjct: 926 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 982
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 2977 bits (7717), Expect = 0.0
Identities = 1494/1936 (77%), Positives = 1704/1936 (88%), Gaps = 5/1936 (0%)
Query: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
D+EMA+FG AAPYLRK EKER+EAQ RPFD KK FV D+K+ +VK I +RE KV +
Sbjct: 4 DAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVK 63
Query: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
T + +T+ DQV NPPKFDKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 64 TLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
Query: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
VTVNPYKWLPVY PEVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDR+NQSILITGESGA
Sbjct: 124 VTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGA 183
Query: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
GKTVNTKRVIQYFA IA GD+ KK+ PGK GTLEDQIIQANP LEAFGNAKTVRNDN
Sbjct: 184 GKTVNTKRVIQYFATIAVTGDK-KKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDN 242
Query: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
SSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQL +ER YHIFYQI+SNKKPEL+D+
Sbjct: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDL 302
Query: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
LLI+ NP+D+ F+SQGE TVASIDD+EEL+ATDNA D+LGF+SEEK +YKLTGA+MH+G
Sbjct: 303 LLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYG 362
Query: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
NMKFK KQREEQAEPDGTE ADK+ YLMGLNSA++LKGLC PRVKVGNEYVTKGQNVQQV
Sbjct: 363 NMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQV 422
Query: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
+ GALAKAVYE+MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 423 TNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 482
Query: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
TNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 483 TNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMF 542
Query: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
PKATD +FK KL+D HLGKS NFQKP+ KGK EAHFSL+HYAG VDYNI GWL KNKDP
Sbjct: 543 PKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDP 602
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKG--KGKAKKGSSFQTVSALHRENLNKL 658
LNETVVGLYQKSSLKLLS LF+NYAGA+ G KG KKGSSFQTVSA+ RENLNKL
Sbjct: 603 LNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKL 662
Query: 659 MTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 718
MTNLRSTHPHFVRC+IPNETK+PGVMD+ LVMHQLRCNGVLEGIRICRKGFP+RILY DF
Sbjct: 663 MTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADF 722
Query: 719 RQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 778
+QRYRILN +AIPEGQFIDS+ +EKLL+S+D+D Q++FG+TKVFFKAGLLGLLEEMRD
Sbjct: 723 KQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRD 782
Query: 779 ERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKP 838
E+L ++T QA RG L R+E+KK++ERRDS+ IQ+NIR+FM VK+WPWM L+FKIKP
Sbjct: 783 EKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKP 842
Query: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
LLKSAE EKEMA+MKE+F R KE L +SEARRKELEEKMVSLLQEKNDLQLQVQ+E +NL
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902
Query: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
DAEERC+ LIK+KI LEAKVKE+ ERLE+EEEMN+EL AKKR LED+CS LKRDIDDLE
Sbjct: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE 962
Query: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
LTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQ LDDLQ EEDKVN
Sbjct: 963 LTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVN 1022
Query: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
L K KLEQQ DDLEGSLEQEKK+R DLERAKRKLEGDLK++QESIMDLENDKQQ++E
Sbjct: 1023 GLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEE 1082
Query: 1079 RLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD 1138
+LKKK+FEL+ L A+I+DEQ Q QKK+KELQARIEELEEE+EAE T RAK+EK RSD
Sbjct: 1083 KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142
Query: 1139 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1198
L+RELEEISERLEEA GATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKK AD
Sbjct: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202
Query: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
SVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + K+K+N+E+ CRT+EDQ +E
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSE 1262
Query: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQ 1318
++K E+ + ++DL Q+A+LQT+NGELS +++EKE+LISQLT+ K TQQLE+LKRQ
Sbjct: 1263 IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQ 1322
Query: 1319 LEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378
+EEE KAKNA+AHALQS+RHDCDLLREQYEEE EAKAELQR LSKANSEVAQWRTKYETD
Sbjct: 1323 MEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382
Query: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1438
AIQRTEELEEAKKKLAQRLQEAEE E N+KC+SLEKTK RLQ E+EDLM D+ERS+ A
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442
Query: 1439 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1498
A LDKKQRNFDK+LAEWKQK +ESQ+ELE++QKE+RSLSTELFK++NAYEE ++ LET
Sbjct: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETL 1502
Query: 1499 KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKI 1558
+RENKNLQEEISDLTEQ+ +GK + E EK +K +E EK +LQ ALEE E SLEHEE KI
Sbjct: 1503 RRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562
Query: 1559 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM 1618
LR QLE +Q+K+E++RK+ EKDEE+EQ KRN R ++LQ+ LDAE RSRN+ALR+KKKM
Sbjct: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622
Query: 1619 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1678
EGDLNEMEIQL H+NR AE QK ++++Q LKD+Q+ LDDA+R+N+DLKE +AIVERRN
Sbjct: 1623 EGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN 1682
Query: 1679 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ 1738
LL ELEE++ +EQTER+R+L+EQEL++ S+RVQLLHSQNTSLIN KKK++AD++Q Q
Sbjct: 1683 GLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ 1742
Query: 1739 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
EVE ++QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLD
Sbjct: 1743 AEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1802
Query: 1799 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 1858
EAEQ+ALKGGKKQ+QKLE RVRELENEL+ EQKR AE++KG K ER++KE+TYQ EED
Sbjct: 1803 EAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDH 1862
Query: 1859 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1918
KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQANT LS+ R+VQHEL+EA ERADIAESQVN
Sbjct: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVN 1922
Query: 1919 KLRAKSRDIGTKGLNE 1934
KLRAKSRD+G++ + E
Sbjct: 1923 KLRAKSRDVGSQKMEE 1938
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 2678 bits (6942), Expect = 0.0
Identities = 1341/1931 (69%), Positives = 1645/1931 (85%), Gaps = 9/1931 (0%)
Query: 5 EMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSRE-GGKVTAET 63
+++ G +A YLR+ +E + T P+D KK V+VPD++ +V+A++ S GG+VT ET
Sbjct: 45 DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104
Query: 64 EYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCV 123
+ K + V+E ++ NPP+FD +EDMAM+T L+E +VL+NL+ RY WMIYTYSGLFCV
Sbjct: 105 KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164
Query: 124 TVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAG 183
T+NPYKWLPVYT VVAAY+GK+RS++PPHI++++DNAY ML +R+NQS+LITGESGAG
Sbjct: 165 TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224
Query: 184 KTVNTKRVIQYFAVIAAIGDR-SKKDQ---SPGKGTLEDQIIQANPALEAFGNAKTVRND 239
KTVNTKRVIQYFA++AA+GD KK Q + GTLEDQII+ANPA+EAFGNAKT+RND
Sbjct: 225 KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284
Query: 240 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLD 299
NSSRFGKFIRIHFG +GKLASADI++YLLEKSRVIFQL ER YH++YQILS +KPEL D
Sbjct: 285 NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344
Query: 300 MLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHF 359
MLL++ NPYDY F SQG TV +++D EEL+ATD+A D+LGF+ +EK + YK+ GA++HF
Sbjct: 345 MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404
Query: 360 GNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQ 419
GNMKFK KQREEQAE DGTE ADK+AYLMG++S DLLKGL HPRV+VGNEYVTKGQ+V+Q
Sbjct: 405 GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464
Query: 420 VIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 479
V++A GALAKA Y+R+F W+V+RIN TL+TK PRQ+FIGVLDIAGFEIF+FNSFEQLCIN
Sbjct: 465 VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524
Query: 480 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 539
FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DLQ CIDLIEKP+GI+SILEEECM
Sbjct: 525 FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584
Query: 540 FPKATDMTFKAKLFDNHLGKSANFQKPR-NIKGKPEAHFSLIHYAGIVDYNIIGWLQKNK 598
FPKA+D +F+AKL+DNH GKS NFQ+PR + K K +AHF ++HYAG+V Y+I+GWL+KNK
Sbjct: 585 FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644
Query: 599 DPLNETVVGLYQKSSLKLLSTLFANYAGA---DAPIEKGKGKAKKGSSFQTVSALHRENL 655
DPLNETVV ++QKS +LL+TL+ NYAG+ + P K K KK +SFQTVS LH+ENL
Sbjct: 645 DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENL 704
Query: 656 NKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILY 715
NKLMTNLR+T PHFVRCI+PNE K+PGVMD LV+HQLRCNGVLEGIRICR+GFPNR+LY
Sbjct: 705 NKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLY 764
Query: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEE 775
DFRQRYRILNP+AIP+ F+DSRK EKLL SLD+DH QY+FGHTKVFFKAGLLG+LEE
Sbjct: 765 TDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEE 824
Query: 776 MRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFK 835
+RD+RL++++T +QA+SRG L R+EY++LL RD+L IQWNIRAF VKNW WMKL+FK
Sbjct: 825 LRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFK 884
Query: 836 IKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQ 895
+KPLL+SA+ E+E+A+++ E L+ AL +EA+R+ELEE VS+ QEKNDL LQ+QAEQ
Sbjct: 885 MKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQ 944
Query: 896 DNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDID 955
DNLADAEERC LIK+K+QLE KVKE++ERLEDEEE+NA+L A++RKLEDEC+ELK+DID
Sbjct: 945 DNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDID 1004
Query: 956 DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEED 1015
DL+LTLAK EKEK ATENKVKNLTEEMA LDE +A+LTKEKKALQEAHQQAL DLQAEED
Sbjct: 1005 DLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEED 1064
Query: 1016 KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ 1075
+V+ LTKAK++LEQQV+DLE SLEQEKK+RMD ERAKRKLEGDLKLTQES+ D DKQQ
Sbjct: 1065 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1124
Query: 1076 LDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKL 1135
L+E+LKKKD EL+ L+ R+EDEQ LG+Q+QKK+KELQAR EELEEELEAER ARA+VEK
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1184
Query: 1136 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1195
R++ +RELEE+SERLEEAGGA++ Q E +KREAE ++RR+LEEA L+HEAT AALR+K
Sbjct: 1185 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRK 1244
Query: 1196 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
A+ AELGEQ+D+LQRV+QKLEKEKSE ++E+DD+ +N+E + +AKA+ EK+CRT EDQ
Sbjct: 1245 QAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQ 1304
Query: 1256 MNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDL 1315
++E + K EE QR + D ++QR +LQTE+GELSR L+EKE LISQL+RGK Q LE+L
Sbjct: 1305 LSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEEL 1364
Query: 1316 KRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY 1375
+RQLEEE KAK+ALAHA+Q+ RHDCDLLREQ+EEE EA+AELQR+LSKAN+EVAQWR+KY
Sbjct: 1365 RRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 1424
Query: 1376 ETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS 1435
E DAIQRTEELEEAKKKLA RLQEAEE VEA NAKCSSLEK K RLQ E ED+ +++ER+
Sbjct: 1425 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 1484
Query: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
+AAAALDKKQR+ ++ L E +++ EE Q ELE++Q+E+R L TELF+L++ +EE+LE L
Sbjct: 1485 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL 1544
Query: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
ET KRENKNLQEEISDLT+Q+ SGK+I ELEK +K LE EK E+Q+ALEEAE +LE EE
Sbjct: 1545 ETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEE 1604
Query: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK 1615
K LR QLE +Q+KAE++RKLAEKDEE +RNH R V+SLQ SLDAETR+RNEALR+K
Sbjct: 1605 TKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLK 1664
Query: 1616 KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVE 1675
KKMEGDLN++E+QL HA R A EAQ + +Q+ LK+ Q D+ R +L E +E
Sbjct: 1665 KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1724
Query: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLS 1735
RR +LL AELEELRA +EQ ERSR+LAEQEL+E +ER+ LLHSQNT L+NQKKK++ADL+
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLA 1784
Query: 1736 QLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1795
QL EVEEA QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK +EQT+++LQ
Sbjct: 1785 QLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQA 1844
Query: 1796 RLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTE 1855
RL+EAEQ AL+GGKKQ+QKLEA+VRELE EL+AEQK++AE++KG+RK ERR+KEL YQ E
Sbjct: 1845 RLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAE 1904
Query: 1856 EDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAES 1915
EDRKNL R+QDLVDKLQ KVK+YKRQ EEAE+QANTNL+K+RK QHELD+AEERAD+AE+
Sbjct: 1905 EDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAET 1964
Query: 1916 QVNKLRAKSRD 1926
Q NKLRA++RD
Sbjct: 1965 QANKLRARTRD 1975
Score = 154 bits (388), Expect = 1e-36
Identities = 152/699 (21%), Positives = 300/699 (42%), Gaps = 54/699 (7%)
Query: 848 EMASMKEEFTRLKEALEK---------SEARRK--ELEEKMVSLLQEKNDLQLQVQAEQD 896
++A+ E TR K + EK SEA+ K EL+ ++ ++ LQ +
Sbjct: 1279 DLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSR 1338
Query: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
L + E QL + K ++E+ +LE+E + + L + L +C L+ ++
Sbjct: 1339 LLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE 1398
Query: 957 LELTLAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKKALQEAHQQALDDLQAEED 1015
A++++ +V + A + +L + KK L Q+A + ++A
Sbjct: 1399 EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 1458
Query: 1016 KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ 1075
K ++L KAK++L+ + +D+ LE+ L++ +R LE L+ + +++ + +
Sbjct: 1459 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEA 1518
Query: 1076 LDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKL 1135
+ EL L E+ L+++ K LQ I +L +++ + ++EK
Sbjct: 1519 AQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKT 1578
Query: 1136 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1195
+ L E EI LEEA GA ++ + + E +++ +++ + + A LR+
Sbjct: 1579 KKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRN 1638
Query: 1196 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
H +V L +D R + + + K + + +L+D+ + + + R ++ Q
Sbjct: 1639 HQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQ 1698
Query: 1256 MNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDL 1315
+ E ++ +E QR +L Q L+ L+ +L+E A + Q R + Q+L +
Sbjct: 1699 LKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEA 1758
Query: 1316 KRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW--RT 1373
+L L + + D L + EE + + E + KA ++ A
Sbjct: 1759 TERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEEL 1818
Query: 1374 KYETDAIQRTEE----LEEAKKKLAQRLQEAEEA--------VEAVNAKCSSLE------ 1415
K E D E LE+ ++L RL+EAE+A V+ + AK LE
Sbjct: 1819 KKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAE 1878
Query: 1416 KTKH--------RLQNEIEDLMVDVE--RSNAAAAA-----LDKKQRNFDKILAEWKQ-- 1458
+ KH + + +++L E R N A L K +++ + E +Q
Sbjct: 1879 QKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQA 1938
Query: 1459 -----KYEESQSELESSQKEARSLSTELFKLKNAYEESL 1492
KY ++Q EL+ +++ A T+ KL+ ++L
Sbjct: 1939 NTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDAL 1977
Score = 124 bits (310), Expect = 1e-27
Identities = 145/649 (22%), Positives = 286/649 (44%), Gaps = 48/649 (7%)
Query: 1318 QLEEEVKAKNALAHALQSARHDCDLLREQYEEE----TEAKAELQRVLSKANSEVAQWRT 1373
Q EEE+ A A L+ A + R++ EE T+ K +L L +A
Sbjct: 893 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 952
Query: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
+ I+ +LE K+L++RL++ EE + A+ LE L+ +I+DL + +
Sbjct: 953 RCHL-LIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLA 1011
Query: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
++ A + K +N L E +ES + L +K + + A E+ +
Sbjct: 1012 KAEKEKQATENKVKN----LTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVS 1067
Query: 1494 HLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEH 1553
L K L++++ DL L K + E+ +++LE + Q ++ +A +
Sbjct: 1068 ALTKAKLR---LEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1124
Query: 1554 EEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALR 1613
E K+ + E +Q+ +E + + ++ K R + L+ L+AE +R +
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA-EELEEELEAERAARARVEK 1183
Query: 1614 VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI 1673
+ + +L E+ +L A +A ++ + ++ L + +L++A ++ +A
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHE---ATVAA 1240
Query: 1674 VERRNNLLQAELEE----LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729
+ R+ AEL E L+ V ++ E+ + E+ + + V+ L S +
Sbjct: 1241 LRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRT 1300
Query: 1730 MDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT 1789
+ LS+ + +VEE ++ +A + + T++ ++ L++++ + L R K Q+
Sbjct: 1301 YEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQS 1360
Query: 1790 IKDLQHRLDEAEQI--ALKGGKKQLQK---LEARVRELENELEAEQKR-----NAESVKG 1839
+++L+ +L+E + AL + L+ L E E E +AE +R NAE +
Sbjct: 1361 LEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQW 1420
Query: 1840 MRKSERRIKELTYQTEEDRKNL-LRLQDL-------------VDKLQLKVKAYKRQAEEA 1885
K E + T + EE +K L LRLQ+ ++K +L+++
Sbjct: 1421 RSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLE 1480
Query: 1886 EEQANTNLSKFRKVQHELDEA-EERADIAESQVNKLRA---KSRDIGTK 1930
E+A + + K Q L+ A EER E +L A +SR +GT+
Sbjct: 1481 LERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTE 1529
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 2401 bits (6222), Expect = 0.0
Identities = 1198/1927 (62%), Positives = 1553/1927 (80%), Gaps = 7/1927 (0%)
Query: 5 EMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIV-SREGGKVTAET 63
+++ G AA +LR+SE E L Q D KK ++PD + +++A++ S + G V ET
Sbjct: 22 DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
Query: 64 EYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCV 123
G+++++KED++ Q NPP+F+ IEDMAMLT L+E +VL+ LK RYG WMIYTYSGLFCV
Sbjct: 82 ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
Query: 124 TVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAG 183
T+NPYKWLPVY EV+AAY+GK+RSEAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 142 TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
Query: 184 KTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSR 243
KTVN+K +IQYFA IAA+ + KK +G LEDQI+QAN LEAFGNAKT+RNDNSSR
Sbjct: 202 KTVNSKHIIQYFATIAAMIESRKK-----QGALEDQIMQANTILEAFGNAKTLRNDNSSR 256
Query: 244 FGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLI 303
FGKFIR+HFGA G L+S DI+ YLLEKSRVIFQ ER+YHIFYQILS +K EL D+LL+
Sbjct: 257 FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
Query: 304 TNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMK 363
+ NP D+ F S G TV S+DDAEEL+AT+ A D+LGF +EK YKLTGAIMHFGNMK
Sbjct: 316 SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
Query: 364 FKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYA 423
FK K REEQ E DGTE ADK+A+LMG+NS++L+K L HPR+KVGNEYVT+GQ ++QV A
Sbjct: 376 FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
Query: 424 TGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNE 483
GAL+K++YERMF W+V RIN L+ K RQ+FIG+LDI GFEI ++NS EQLCINFTNE
Sbjct: 436 VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
Query: 484 KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKA 543
KLQQFFN HMFVLEQEEYKKE IEW I FG+DLQACIDLIEKPMGI+SILEEECMFPKA
Sbjct: 496 KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
Query: 544 TDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNE 603
TD+TFK KLFDNH GKS + QKP+ K K EAHF L+HYAG+V YNI GWL+KNKD LNE
Sbjct: 556 TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
Query: 604 TVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLR 663
TVV ++QKSS +LL++LF NY D+ I G+ K KKG+SFQTV++LH+ENLNKLMTNL+
Sbjct: 616 TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLK 675
Query: 664 STHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYR 723
ST PHFVRCI PN K PG++D LV+ QLRCNGVLEG RICR+GFPNR+ Y DF+QRY
Sbjct: 676 STAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYC 735
Query: 724 ILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSR 783
ILNP P+ +F+ SRK AE+LL SL+IDH QY+FG TKVFFKAG LG LE +RDERLS+
Sbjct: 736 ILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSK 795
Query: 784 IITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSA 843
+ T QA+++G L R++++K+LE RD+L++IQWNIRAFM VKNWPWM+L+FKIKPL+KS+
Sbjct: 796 VFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSS 855
Query: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
E +E+A +KEE +L++ALEKSE +R+EL+ K VSL QEKNDL LQ+QAEQ+ LA+ EE
Sbjct: 856 EVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEE 915
Query: 904 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963
+C+ LIK+KIQLEA+VKE++ER+E+EEE+N+ELTA+ RKLEDEC ELK++IDDLE L K
Sbjct: 916 QCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVK 975
Query: 964 VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
EKEK TE+KVKNLTEE+ L+E I+KL + K +QEAHQQ LDDL EE+K+++L+KA
Sbjct: 976 SEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKA 1035
Query: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
+KLEQQVD+LEG+LEQE+K RM+ ER KLEG+LKL +ES+ +LE+ ++ L E L+KK
Sbjct: 1036 NLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKK 1095
Query: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
+ EL+ +N+++E+E+ L +QLQK +KELQ +I++L+E+LEAERT RAK+E+ R+DL+++L
Sbjct: 1096 ELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDL 1155
Query: 1144 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1203
+++ERLEE GG++ Q+E+ KK+E +FQK+ RD+EEATL E T+A+L+K+HADS+AEL
Sbjct: 1156 ADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAEL 1215
Query: 1204 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA 1263
Q++NLQ+VKQKLEK+KS+ +LE+DD+ + +EQ+ +AKAN EK+C E++++E +K
Sbjct: 1216 EGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKL 1275
Query: 1264 EETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEV 1323
++ + NDL +Q+ KL +E+GE R+L+EKEALI+QL+R K +T+Q+EDL+ QLE+E
Sbjct: 1276 DKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKET 1335
Query: 1324 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1383
K+++ALAHALQ A+ DCDLLREQYEEE E KAEL R LSK N+E+ QWR KYE + IQRT
Sbjct: 1336 KSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRT 1395
Query: 1384 EELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
E+LE+AKK+LA RLQEA EA+ NA+ +SLE+ +H+LQ E+ D + D+ + +AAA LD
Sbjct: 1396 EDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLD 1455
Query: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503
+KQ K LA+WKQK+EESQ+ L++SQKE ++LSTEL KLKN YEES+ ET +RENK
Sbjct: 1456 QKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENK 1515
Query: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
NLQEEIS+LT Q+ K + E+EKV+K +E EK E+Q LEE E +LE E KIL QL
Sbjct: 1516 NLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQL 1575
Query: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
E + KAE+ERKL+EKDEE+E +R +DSLQ+SLD+E +SR E R+KKKME DLN
Sbjct: 1576 ELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLN 1635
Query: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
EME+QLS ANR +EA K + LQ +KD Q+QLDD+ + N DLKE +A+ ERRN+LLQ+
Sbjct: 1636 EMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQS 1695
Query: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEE 1743
ELE+LR++ EQTER R+L+E+EL+E +ER+ L ++QNTSL++QKKK++AD++++Q E EE
Sbjct: 1696 ELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEE 1755
Query: 1744 AVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI 1803
VQEC+NAEEKAKKA +AA ++EELKK+QDT AHLER ++NMEQTI DLQ RL EAEQ+
Sbjct: 1756 VVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQM 1815
Query: 1804 ALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLR 1863
AL G +KQ+QKLE+RVRELE ELE E +R+AE+ +G R+ ER IKELTYQ EED+KNL R
Sbjct: 1816 ALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSR 1875
Query: 1864 LQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923
+Q +DKLQLKV+ YK+Q E AE QAN LSK++K QHEL+E +ERA++AESQVNKL+ K
Sbjct: 1876 MQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIK 1935
Query: 1924 SRDIGTK 1930
+R+ G K
Sbjct: 1936 AREFGKK 1942
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 1445 bits (3740), Expect = 0.0
Identities = 797/1908 (41%), Positives = 1183/1908 (62%), Gaps = 27/1908 (1%)
Query: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
K+ V+VP +KQ F A I +G +V E E GK VTV +D + + NPPKF K+EDMA
Sbjct: 33 KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
Query: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
LT L+E +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PP
Sbjct: 93 LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
Query: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
HI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY AV+A+ + KKD S
Sbjct: 153 HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSI- 210
Query: 213 KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR
Sbjct: 211 TGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSR 270
Query: 273 VIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASIDDAEELM 330
I Q + ER +HIFY +++ K ++ LL+ NN Y F+S G + + D E
Sbjct: 271 AIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN---YTFLSNGFVPIPAAQDDEMFQ 327
Query: 331 ATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGL 390
T A ++GF+ EE+ S+ K+ +++ GN+ FK ++ +QA A K +LMG+
Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
Query: 391 NSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-T 449
N D + + PR+KVG + V K Q +Q +A ALAKA YER+F W++TR+N L+ T
Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 447
Query: 450 KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 509
+ F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 448 HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507
Query: 510 FIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQKP
Sbjct: 508 FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKP 566
Query: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY-- 624
+ +K K E FS+IHYAG VDYN WL KN DPLN+ V L SS K ++ L+ +
Sbjct: 567 KQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
Query: 625 -AGADAPIEKGKG------KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677
G D + + K KKG F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 625 IVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 678 TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737
K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 738 SRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLA 797
++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG LA
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 798 RMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFT 857
R + K ++ ++ VIQ N A++ ++NW W +L+ K+KPLL+ +E+EM + ++E
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 858 RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
+ KE +K+E KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
+ EM RLE+EE+ +L A+++K+ + +L+ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGS 1037
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1038 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDE 1097
L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ EL A AR++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1098 QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1157
A + KK++EL+ I +L+E+L++ER AR K EK + DL ELE + LE+ +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1158 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
+K K + E D+ + + +AK +E + LE Q+ E +SK + +R+ +L +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
KLQ E ++ L+E E +L + + + QL+D + L+EE + K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1457
+ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
+ E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
GK +HELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
+DE+ E+ +R R + +T L+ E + R A KKK+EGDL ++E+Q A +
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757
+RK A+ E E +E + S +L ++K++++A ++QL+ E+EE ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1817
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
Query: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
++ +LE ++E E + + K +++ ++++KE+ Q E++RK + ++ +K +VK
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 1878 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 199 bits (507), Expect = 2e-50
Identities = 203/912 (22%), Positives = 408/912 (44%), Gaps = 120/912 (13%)
Query: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136
+E ++ K+ EL R + + +L++K +L L+E+L+AE A+ E++R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1196
L+ + +E+ E L E + + ++ +AE RKK
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 948
Query: 1197 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM---CRTLE 1253
A + +L EQ++ + +QKL+ EK + A+A ++K+ ++
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEK-----------------VTAEAKIKKLEDEILVMD 991
Query: 1254 DQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT---RGKLTYTQ 1310
DQ N+ + + + ++DLT+ A+ + + L++ ++ E++IS+L + + Q
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 1311 QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ 1370
+LE LKR+LE + + LQ+ + + + EEE LQ L++ + E+AQ
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE------LQAALARLDDEIAQ 1105
Query: 1371 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 1430
+ +A+++ ELE + + +E +++ A + EK K L E+E L
Sbjct: 1106 -----KNNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153
Query: 1431 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
++E + + A + + ++ + K+ +E E+ +E R K A EE
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEE 1207
Query: 1491 SLEHLETFKRENKNL-------QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
E LE FKR NL ++E +DL +L G+ E+E +K+LEA+ ELQS
Sbjct: 1208 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK 1267
Query: 1544 LEEAEASLEHEEGKILRAQLEFNQIKA---EIERKLAEKDEEMEQAKRNHLRVVDSLQTS 1600
+ E + K+ + Q E + E E K + +++ + Q
Sbjct: 1268 CSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ----LQDTQEL 1323
Query: 1601 LDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1660
L ETR + +++E + N ++ QL ++ + +L L D++ +L D
Sbjct: 1324 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Query: 1661 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1720
+ L+E ++ L + EE A ++ E+++ +QEL + +
Sbjct: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
Query: 1721 TSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1780
++L +++K D L++ + + E AE +A++ T A +A L++ + LE
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 1781 RMKKNMEQTIKDLQHRLDEAEQIA--LKGGKK----QLQKLEARVRELENELEAEQKR-- 1832
R K ++ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL+A +
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 1833 ----NAESVKGM----------------RKSERRIKELTYQTEEDRKNLL-------RLQ 1865
N +++KG R+ +R++ E + E++RK +L+
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 1866 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERAD--IAESQVNKLRAK 1923
+ L+L+ + + EEA +Q ++ + Q EL++A D A ++ N+ +AK
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 1924 SRDIGTKGLNEE 1935
S + L E+
Sbjct: 1684 SLEADLMQLQED 1695
Score = 132 bits (333), Expect = 3e-30
Identities = 119/559 (21%), Positives = 237/559 (42%), Gaps = 69/559 (12%)
Query: 1373 TKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE---DLM 1429
T+ E + + +EL++ K +R Q+AE ++ + K S L + K+ LQ +++ +L
Sbjct: 848 TRQEEEMQAKEDELQKTK----ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 1430 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
+ E AA K++ ++IL E + + EE + + Q E + ++ ++ L+ E
Sbjct: 904 AEAEEMRVRLAA---KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 1490 ESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEA 1549
E + + E + +I L +++ ++L K RK LE +L + L E E
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE- 1019
Query: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
EK + + + K H ++ L+ L E +SR
Sbjct: 1020 ----------------------------EKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 1610 EALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE 1669
E ++K+K+EGD ++ Q++ AE + Q+ + L+ +LDD + ++ +
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Query: 1670 NIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729
I +E + LQ +L+ RA + E+ QK+
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEK----------------------------QKRD 1143
Query: 1730 MDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNMEQ 1788
+ +L L+TE+E+ + +E K + ++ + L +E + A ++ M++ Q
Sbjct: 1144 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1203
Query: 1789 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIK 1848
+++L +L++ ++ A K Q LE +L EL + E +K E +++
Sbjct: 1204 AVEELTEQLEQFKR-AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 1849 ELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE 1908
EL + + + L D V KLQ +V++ EAE +A + +L + +E
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 1909 RADIAESQVNKLRAKSRDI 1927
Q + K R +
Sbjct: 1323 LLQEETRQKLNVSTKLRQL 1341
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 1445 bits (3740), Expect = 0.0
Identities = 797/1908 (41%), Positives = 1183/1908 (62%), Gaps = 27/1908 (1%)
Query: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
K+ V+VP +KQ F A I +G +V E E GK VTV +D + + NPPKF K+EDMA
Sbjct: 33 KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
Query: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
LT L+E +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PP
Sbjct: 93 LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
Query: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
HI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY AV+A+ + KKD S
Sbjct: 153 HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSI- 210
Query: 213 KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR
Sbjct: 211 TGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSR 270
Query: 273 VIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASIDDAEELM 330
I Q + ER +HIFY +++ K ++ LL+ NN Y F+S G + + D E
Sbjct: 271 AIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN---YTFLSNGFVPIPAAQDDEMFQ 327
Query: 331 ATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGL 390
T A ++GF+ EE+ S+ K+ +++ GN+ FK ++ +QA A K +LMG+
Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
Query: 391 NSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-T 449
N D + + PR+KVG + V K Q +Q +A ALAKA YER+F W++TR+N L+ T
Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 447
Query: 450 KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 509
+ F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 448 HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507
Query: 510 FIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQKP
Sbjct: 508 FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKP 566
Query: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY-- 624
+ +K K E FS+IHYAG VDYN WL KN DPLN+ V L SS K ++ L+ +
Sbjct: 567 KQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
Query: 625 -AGADAPIEKGKG------KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677
G D + + K KKG F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 625 IVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 678 TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737
K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 738 SRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLA 797
++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG LA
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 798 RMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFT 857
R + K ++ ++ VIQ N A++ ++NW W +L+ K+KPLL+ +E+EM + ++E
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 858 RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
+ KE +K+E KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
+ EM RLE+EE+ +L A+++K+ + +L+ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGS 1037
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1038 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDE 1097
L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ EL A AR++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1098 QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1157
A + KK++EL+ I +L+E+L++ER AR K EK + DL ELE + LE+ +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1158 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
+K K + E D+ + + +AK +E + LE Q+ E +SK + +R+ +L +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
KLQ E ++ L+E E +L + + + QL+D + L+EE + K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1457
+ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
+ E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
GK +HELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
+DE+ E+ +R R + +T L+ E + R A KKK+EGDL ++E+Q A +
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757
+RK A+ E E +E + S +L ++K++++A ++QL+ E+EE ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1817
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
Query: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
++ +LE ++E E + + K +++ ++++KE+ Q E++RK + ++ +K +VK
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 1878 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 199 bits (507), Expect = 2e-50
Identities = 203/912 (22%), Positives = 408/912 (44%), Gaps = 120/912 (13%)
Query: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136
+E ++ K+ EL R + + +L++K +L L+E+L+AE A+ E++R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1196
L+ + +E+ E L E + + ++ +AE RKK
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 948
Query: 1197 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM---CRTLE 1253
A + +L EQ++ + +QKL+ EK + A+A ++K+ ++
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEK-----------------VTAEAKIKKLEDEILVMD 991
Query: 1254 DQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT---RGKLTYTQ 1310
DQ N+ + + + ++DLT+ A+ + + L++ ++ E++IS+L + + Q
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 1311 QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ 1370
+LE LKR+LE + + LQ+ + + + EEE LQ L++ + E+AQ
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE------LQAALARLDDEIAQ 1105
Query: 1371 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 1430
+ +A+++ ELE + + +E +++ A + EK K L E+E L
Sbjct: 1106 -----KNNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153
Query: 1431 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
++E + + A + + ++ + K+ +E E+ +E R K A EE
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEE 1207
Query: 1491 SLEHLETFKRENKNL-------QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
E LE FKR NL ++E +DL +L G+ E+E +K+LEA+ ELQS
Sbjct: 1208 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK 1267
Query: 1544 LEEAEASLEHEEGKILRAQLEFNQIKA---EIERKLAEKDEEMEQAKRNHLRVVDSLQTS 1600
+ E + K+ + Q E + E E K + +++ + Q
Sbjct: 1268 CSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ----LQDTQEL 1323
Query: 1601 LDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1660
L ETR + +++E + N ++ QL ++ + +L L D++ +L D
Sbjct: 1324 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Query: 1661 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1720
+ L+E ++ L + EE A ++ E+++ +QEL + +
Sbjct: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
Query: 1721 TSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1780
++L +++K D L++ + + E AE +A++ T A +A L++ + LE
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 1781 RMKKNMEQTIKDLQHRLDEAEQIA--LKGGKK----QLQKLEARVRELENELEAEQKR-- 1832
R K ++ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL+A +
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 1833 ----NAESVKGM----------------RKSERRIKELTYQTEEDRKNLL-------RLQ 1865
N +++KG R+ +R++ E + E++RK +L+
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 1866 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERAD--IAESQVNKLRAK 1923
+ L+L+ + + EEA +Q ++ + Q EL++A D A ++ N+ +AK
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 1924 SRDIGTKGLNEE 1935
S + L E+
Sbjct: 1684 SLEADLMQLQED 1695
Score = 132 bits (333), Expect = 3e-30
Identities = 119/559 (21%), Positives = 237/559 (42%), Gaps = 69/559 (12%)
Query: 1373 TKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE---DLM 1429
T+ E + + +EL++ K +R Q+AE ++ + K S L + K+ LQ +++ +L
Sbjct: 848 TRQEEEMQAKEDELQKTK----ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 1430 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
+ E AA K++ ++IL E + + EE + + Q E + ++ ++ L+ E
Sbjct: 904 AEAEEMRVRLAA---KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 1490 ESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEA 1549
E + + E + +I L +++ ++L K RK LE +L + L E E
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE- 1019
Query: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
EK + + + K H ++ L+ L E +SR
Sbjct: 1020 ----------------------------EKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 1610 EALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE 1669
E ++K+K+EGD ++ Q++ AE + Q+ + L+ +LDD + ++ +
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Query: 1670 NIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729
I +E + LQ +L+ RA + E+ QK+
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEK----------------------------QKRD 1143
Query: 1730 MDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNMEQ 1788
+ +L L+TE+E+ + +E K + ++ + L +E + A ++ M++ Q
Sbjct: 1144 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1203
Query: 1789 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIK 1848
+++L +L++ ++ A K Q LE +L EL + E +K E +++
Sbjct: 1204 AVEELTEQLEQFKR-AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 1849 ELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE 1908
EL + + + L D V KLQ +V++ EAE +A + +L + +E
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 1909 RADIAESQVNKLRAKSRDI 1927
Q + K R +
Sbjct: 1323 LLQEETRQKLNVSTKLRQL 1341
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 1443 bits (3735), Expect = 0.0
Identities = 797/1914 (41%), Positives = 1184/1914 (61%), Gaps = 32/1914 (1%)
Query: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
K+ V+VP +KQ F A I +G +V E E GK VTV +D + + NPPKF K+EDMA
Sbjct: 33 KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
Query: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
LT L+E +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PP
Sbjct: 93 LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
Query: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
HI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY AV+A+ + KKD S
Sbjct: 153 HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSIT 211
Query: 213 KGT------LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 266
+G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY
Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271
Query: 267 LLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASID 324
LLEKSR I Q + ER +HIFY +++ K ++ LL+ NN Y F+S G + +
Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN---YTFLSNGFVPIPAAQ 328
Query: 325 DAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKS 384
D E T A ++GF+ EE+ S+ K+ +++ GN+ FK ++ +QA A K
Sbjct: 329 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 388
Query: 385 AYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRIN 444
+LMG+N D + + PR+KVG + V K Q +Q +A ALAKA YER+F W++TR+N
Sbjct: 389 CHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN 448
Query: 445 ATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 503
L+ T + F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++
Sbjct: 449 KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 508
Query: 504 EGIEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKS 560
EGIEW FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G
Sbjct: 509 EGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSH 567
Query: 561 ANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTL 620
FQKP+ +K K E FS+IHYAG VDYN WL KN DPLN+ V L SS K ++ L
Sbjct: 568 PKFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 621 FANY---AGADAPIEKGKG------KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
+ + G D + + K KKG F+TV L++E L KLMT LR+T P+FVR
Sbjct: 626 WKDVDRIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVR 684
Query: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
CIIPN K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP
Sbjct: 685 CIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIP 744
Query: 732 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
+G F+D ++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA
Sbjct: 745 KG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAM 803
Query: 792 SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMAS 851
RG LAR + K ++ ++ VIQ N A++ ++NW W +L+ K+KPLL+ +E+EM +
Sbjct: 804 CRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA 863
Query: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
++E + KE +K+E KELE+K L +EKN LQ Q+QAE + A+AEE +L
Sbjct: 864 KEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 923
Query: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
K +LE + EM RLE+EE+ +L A+++K+ + +L+ +++ E K++ EK
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
E K+K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043
Query: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
+LE L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ EL A
Sbjct: 1044 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1103
Query: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1151
AR++DE A + KK++EL+ I +L+E+L++ER AR K EK + DL ELE + LE
Sbjct: 1104 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Query: 1152 EAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQ 1211
+ +T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 1212 RVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVN 1271
R K L+K K + E D+ + + +AK +E + LE Q+ E +SK + +R+
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283
Query: 1272 DLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAH 1331
+L + KLQ E ++ L+E E +L + + + QL+D + L+EE + K ++
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343
Query: 1332 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1391
L+ + + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKK 1402
Query: 1392 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 1451
+ + ++ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD+
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
Query: 1452 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 1511
+LAE K + E + ++ EAR T+ L A EE+LE E +R NK L+ E+ D
Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522
Query: 1512 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 1571
L GK +HELEK ++ LE + E+++ LEE E L+ E LR ++ +K +
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
ER L +DE+ E+ +R R + +T L+ E + R A KKK+EGDL ++E+Q
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADS 1642
Query: 1632 ANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAV 1691
A + EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 1692 VEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNA 1751
+ ER+RK A+ E E +E + S +L ++K++++A ++QL+ E+EE
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 1752 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQ 1811
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822
Query: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
+ LEA++ +LE ++E E + + K +++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882
Query: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
+VK KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 199 bits (507), Expect = 2e-50
Identities = 203/912 (22%), Positives = 408/912 (44%), Gaps = 120/912 (13%)
Query: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136
+E ++ K+ EL R + + +L++K +L L+E+L+AE A+ E++R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1196
L+ + +E+ E L E + + ++ +AE RKK
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 955
Query: 1197 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM---CRTLE 1253
A + +L EQ++ + +QKL+ EK + A+A ++K+ ++
Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEK-----------------VTAEAKIKKLEDEILVMD 998
Query: 1254 DQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT---RGKLTYTQ 1310
DQ N+ + + + ++DLT+ A+ + + L++ ++ E++IS+L + + Q
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 1311 QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ 1370
+LE LKR+LE + + LQ+ + + + EEE LQ L++ + E+AQ
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE------LQAALARLDDEIAQ 1112
Query: 1371 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 1430
+ +A+++ ELE + + +E +++ A + EK K L E+E L
Sbjct: 1113 -----KNNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160
Query: 1431 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
++E + + A + + ++ + K+ +E E+ +E R K A EE
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEE 1214
Query: 1491 SLEHLETFKRENKNL-------QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
E LE FKR NL ++E +DL +L G+ E+E +K+LEA+ ELQS
Sbjct: 1215 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK 1274
Query: 1544 LEEAEASLEHEEGKILRAQLEFNQIKA---EIERKLAEKDEEMEQAKRNHLRVVDSLQTS 1600
+ E + K+ + Q E + E E K + +++ + Q
Sbjct: 1275 CSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ----LQDTQEL 1330
Query: 1601 LDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1660
L ETR + +++E + N ++ QL ++ + +L L D++ +L D
Sbjct: 1331 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390
Query: 1661 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1720
+ L+E ++ L + EE A ++ E+++ +QEL + +
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450
Query: 1721 TSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1780
++L +++K D L++ + + E AE +A++ T A +A L++ + LE
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 1781 RMKKNMEQTIKDLQHRLDEAEQIA--LKGGKK----QLQKLEARVRELENELEAEQKR-- 1832
R K ++ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL+A +
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570
Query: 1833 ----NAESVKGM----------------RKSERRIKELTYQTEEDRKNLL-------RLQ 1865
N +++KG R+ +R++ E + E++RK +L+
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 1866 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERAD--IAESQVNKLRAK 1923
+ L+L+ + + EEA +Q ++ + Q EL++A D A ++ N+ +AK
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 1924 SRDIGTKGLNEE 1935
S + L E+
Sbjct: 1691 SLEADLMQLQED 1702
Score = 132 bits (333), Expect = 3e-30
Identities = 119/559 (21%), Positives = 237/559 (42%), Gaps = 69/559 (12%)
Query: 1373 TKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE---DLM 1429
T+ E + + +EL++ K +R Q+AE ++ + K S L + K+ LQ +++ +L
Sbjct: 855 TRQEEEMQAKEDELQKTK----ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 1430 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
+ E AA K++ ++IL E + + EE + + Q E + ++ ++ L+ E
Sbjct: 911 AEAEEMRVRLAA---KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967
Query: 1490 ESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEA 1549
E + + E + +I L +++ ++L K RK LE +L + L E E
Sbjct: 968 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE- 1026
Query: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
EK + + + K H ++ L+ L E +SR
Sbjct: 1027 ----------------------------EKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 1610 EALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE 1669
E ++K+K+EGD ++ Q++ AE + Q+ + L+ +LDD + ++ +
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1118
Query: 1670 NIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729
I +E + LQ +L+ RA + E+ QK+
Sbjct: 1119 KIRELEGHISDLQEDLDSERAARNKAEK----------------------------QKRD 1150
Query: 1730 MDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNMEQ 1788
+ +L L+TE+E+ + +E K + ++ + L +E + A ++ M++ Q
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1210
Query: 1789 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIK 1848
+++L +L++ ++ A K Q LE +L EL + E +K E +++
Sbjct: 1211 AVEELTEQLEQFKR-AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 1849 ELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE 1908
EL + + + L D V KLQ +V++ EAE +A + +L + +E
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 1909 RADIAESQVNKLRAKSRDI 1927
Q + K R +
Sbjct: 1330 LLQEETRQKLNVSTKLRQL 1348
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 1443 bits (3735), Expect = 0.0
Identities = 797/1914 (41%), Positives = 1184/1914 (61%), Gaps = 32/1914 (1%)
Query: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
K+ V+VP +KQ F A I +G +V E E GK VTV +D + + NPPKF K+EDMA
Sbjct: 33 KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
Query: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
LT L+E +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PP
Sbjct: 93 LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
Query: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
HI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY AV+A+ + KKD S
Sbjct: 153 HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSIT 211
Query: 213 KGT------LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 266
+G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY
Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271
Query: 267 LLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASID 324
LLEKSR I Q + ER +HIFY +++ K ++ LL+ NN Y F+S G + +
Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN---YTFLSNGFVPIPAAQ 328
Query: 325 DAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKS 384
D E T A ++GF+ EE+ S+ K+ +++ GN+ FK ++ +QA A K
Sbjct: 329 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 388
Query: 385 AYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRIN 444
+LMG+N D + + PR+KVG + V K Q +Q +A ALAKA YER+F W++TR+N
Sbjct: 389 CHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN 448
Query: 445 ATLE-TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 503
L+ T + F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++
Sbjct: 449 KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 508
Query: 504 EGIEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKS 560
EGIEW FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G
Sbjct: 509 EGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSH 567
Query: 561 ANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTL 620
FQKP+ +K K E FS+IHYAG VDYN WL KN DPLN+ V L SS K ++ L
Sbjct: 568 PKFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 621 FANY---AGADAPIEKGKG------KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671
+ + G D + + K KKG F+TV L++E L KLMT LR+T P+FVR
Sbjct: 626 WKDVDRIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVR 684
Query: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731
CIIPN K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP
Sbjct: 685 CIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIP 744
Query: 732 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ 791
+G F+D ++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA
Sbjct: 745 KG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAM 803
Query: 792 SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMAS 851
RG LAR + K ++ ++ VIQ N A++ ++NW W +L+ K+KPLL+ +E+EM +
Sbjct: 804 CRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA 863
Query: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
++E + KE +K+E KELE+K L +EKN LQ Q+QAE + A+AEE +L
Sbjct: 864 KEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 923
Query: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
K +LE + EM RLE+EE+ +L A+++K+ + +L+ +++ E K++ EK
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
E K+K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043
Query: 1032 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN 1091
+LE L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ EL A
Sbjct: 1044 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1103
Query: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1151
AR++DE A + KK++EL+ I +L+E+L++ER AR K EK + DL ELE + LE
Sbjct: 1104 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Query: 1152 EAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQ 1211
+ +T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 1212 RVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVN 1271
R K L+K K + E D+ + + +AK +E + LE Q+ E +SK + +R+
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283
Query: 1272 DLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAH 1331
+L + KLQ E ++ L+E E +L + + + QL+D + L+EE + K ++
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343
Query: 1332 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1391
L+ + + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKK 1402
Query: 1392 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 1451
+ + ++ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD+
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
Query: 1452 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 1511
+LAE K + E + ++ EAR T+ L A EE+LE E +R NK L+ E+ D
Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522
Query: 1512 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 1571
L GK +HELEK ++ LE + E+++ LEE E L+ E LR ++ +K +
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
ER L +DE+ E+ +R R + +T L+ E + R A KKK+EGDL ++E+Q
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADS 1642
Query: 1632 ANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAV 1691
A + EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 1692 VEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNA 1751
+ ER+RK A+ E E +E + S +L ++K++++A ++QL+ E+EE
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 1752 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQ 1811
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822
Query: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
+ LEA++ +LE ++E E + + K +++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882
Query: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
+VK KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 199 bits (507), Expect = 2e-50
Identities = 203/912 (22%), Positives = 408/912 (44%), Gaps = 120/912 (13%)
Query: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136
+E ++ K+ EL R + + +L++K +L L+E+L+AE A+ E++R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1196
L+ + +E+ E L E + + ++ +AE RKK
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 955
Query: 1197 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM---CRTLE 1253
A + +L EQ++ + +QKL+ EK + A+A ++K+ ++
Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEK-----------------VTAEAKIKKLEDEILVMD 998
Query: 1254 DQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT---RGKLTYTQ 1310
DQ N+ + + + ++DLT+ A+ + + L++ ++ E++IS+L + + Q
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 1311 QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ 1370
+LE LKR+LE + + LQ+ + + + EEE LQ L++ + E+AQ
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE------LQAALARLDDEIAQ 1112
Query: 1371 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 1430
+ +A+++ ELE + + +E +++ A + EK K L E+E L
Sbjct: 1113 -----KNNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160
Query: 1431 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
++E + + A + + ++ + K+ +E E+ +E R K A EE
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEE 1214
Query: 1491 SLEHLETFKRENKNL-------QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
E LE FKR NL ++E +DL +L G+ E+E +K+LEA+ ELQS
Sbjct: 1215 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK 1274
Query: 1544 LEEAEASLEHEEGKILRAQLEFNQIKA---EIERKLAEKDEEMEQAKRNHLRVVDSLQTS 1600
+ E + K+ + Q E + E E K + +++ + Q
Sbjct: 1275 CSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ----LQDTQEL 1330
Query: 1601 LDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1660
L ETR + +++E + N ++ QL ++ + +L L D++ +L D
Sbjct: 1331 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390
Query: 1661 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1720
+ L+E ++ L + EE A ++ E+++ +QEL + +
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450
Query: 1721 TSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1780
++L +++K D L++ + + E AE +A++ T A +A L++ + LE
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 1781 RMKKNMEQTIKDLQHRLDEAEQIA--LKGGKK----QLQKLEARVRELENELEAEQKR-- 1832
R K ++ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL+A +
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570
Query: 1833 ----NAESVKGM----------------RKSERRIKELTYQTEEDRKNLL-------RLQ 1865
N +++KG R+ +R++ E + E++RK +L+
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 1866 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERAD--IAESQVNKLRAK 1923
+ L+L+ + + EEA +Q ++ + Q EL++A D A ++ N+ +AK
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 1924 SRDIGTKGLNEE 1935
S + L E+
Sbjct: 1691 SLEADLMQLQED 1702
Score = 132 bits (333), Expect = 3e-30
Identities = 119/559 (21%), Positives = 237/559 (42%), Gaps = 69/559 (12%)
Query: 1373 TKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE---DLM 1429
T+ E + + +EL++ K +R Q+AE ++ + K S L + K+ LQ +++ +L
Sbjct: 855 TRQEEEMQAKEDELQKTK----ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 1430 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
+ E AA K++ ++IL E + + EE + + Q E + ++ ++ L+ E
Sbjct: 911 AEAEEMRVRLAA---KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967
Query: 1490 ESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEA 1549
E + + E + +I L +++ ++L K RK LE +L + L E E
Sbjct: 968 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE- 1026
Query: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
EK + + + K H ++ L+ L E +SR
Sbjct: 1027 ----------------------------EKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 1610 EALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE 1669
E ++K+K+EGD ++ Q++ AE + Q+ + L+ +LDD + ++ +
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1118
Query: 1670 NIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729
I +E + LQ +L+ RA + E+ QK+
Sbjct: 1119 KIRELEGHISDLQEDLDSERAARNKAEK----------------------------QKRD 1150
Query: 1730 MDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNMEQ 1788
+ +L L+TE+E+ + +E K + ++ + L +E + A ++ M++ Q
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1210
Query: 1789 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIK 1848
+++L +L++ ++ A K Q LE +L EL + E +K E +++
Sbjct: 1211 AVEELTEQLEQFKR-AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 1849 ELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE 1908
EL + + + L D V KLQ +V++ EAE +A + +L + +E
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 1909 RADIAESQVNKLRAKSRDI 1927
Q + K R +
Sbjct: 1330 LLQEETRQKLNVSTKLRQL 1348
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 1428 bits (3696), Expect = 0.0
Identities = 786/1907 (41%), Positives = 1173/1907 (61%), Gaps = 28/1907 (1%)
Query: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
KK V+VP DK F A + G + E E GK V V +D + + NPPKF K+EDMA
Sbjct: 29 KKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAE 88
Query: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
LT L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ E+V Y+GKKR E PP
Sbjct: 89 LTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPP 148
Query: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
HI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +SKKDQ
Sbjct: 149 HIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS-SHKSKKDQ--- 204
Query: 213 KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 205 -GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
Query: 273 VIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYD-YAFISQGETTVASIDDAEELMA 331
I Q K ER +HIFY +LS L LL+ PY+ Y F+S G T+ D +
Sbjct: 264 AIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQE 321
Query: 332 TDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLN 391
T A ++G EE+ + ++ ++ GN+ FK ++ +QA A K ++L+G+N
Sbjct: 322 TMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGIN 381
Query: 392 SADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-TK 450
D +G+ PR+KVG +YV K Q +Q +A ALAKA YERMF W+V RIN L+ TK
Sbjct: 382 VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
Query: 451 QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 510
+ FIG+LDIAGFEIFD NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW F
Sbjct: 442 RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
Query: 511 IDFGMDLQACIDLIEKPMG---IMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPR 567
IDFG+DLQ CIDLIEKP G I+++L+EEC FPKATD +F K+ G FQKP+
Sbjct: 502 IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQKPK 560
Query: 568 NIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY--- 624
+K K A F +IHYAG VDY WL KN DPLN+ + L +SS K +S L+ +
Sbjct: 561 QLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRI 618
Query: 625 ------AGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNET 678
AG G K +KG F+TV L++E L KLM LR+T+P+FVRCIIPN
Sbjct: 619 IGLDQVAGMSETALPGAFKTRKGM-FRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHE 677
Query: 679 KSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDS 738
K G +D LV+ QLRCNGVLEGIRICR+GFPNR+++ +FRQRY IL P +IP+G F+D
Sbjct: 678 KKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDG 736
Query: 739 RKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLAR 798
++ ++ +L++D N Y+ G +KVFF+AG+L LEE RD +++ +I QA RG LAR
Sbjct: 737 KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796
Query: 799 MEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858
+ K ++ ++ V+Q N A++ ++NW W +L+ K+KPLL+ + +E+EM + +EE +
Sbjct: 797 KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856
Query: 859 LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAK 918
++E +E R E+E L+ EK LQ Q+QAE + A+AEE +L K +LE
Sbjct: 857 VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
Query: 919 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978
++ R+E+EEE L A+K+K++ EL+ +++ E K++ EK TE K+K L
Sbjct: 917 CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
Query: 979 TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSL 1038
EE L++ KL KEKK L++ + +L EE+K +L K K K E + DLE L
Sbjct: 977 EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 1039 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQ 1098
+E+K R +LE+ +RKLEGD + I +L+ +L +L KK+ EL A AR+E+E
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
A + KK++EL+++I EL+E+LE+ER +R K EK + DL ELE + LE+ +T+
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Q E+ KRE E +++ LEE HEA +R+KH+ +V EL EQ++ +RVK LE
Sbjct: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216
Query: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278
K K + E ++ + ++ +++ K + E + +E Q+ E + K E +R +L +
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
Query: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338
KLQ E ++ L + ++ S+LT+ QL+D + L+EE + K +L+ L+
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
Query: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398
+ + REQ EEE EAK L++ ++ +++VA + K E D++ E EE K+KL + L+
Sbjct: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLE 1395
Query: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458
+ E A LEKTK RLQ E++DL+VD++ +A L+KKQ+ FD++LAE K
Sbjct: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518
+ E + ++ EAR T+ L A EE++E +R NK + E+ DL
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
Query: 1519 SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1578
GK++HELEK ++ LE + E+++ LEE E L+ E LR ++ +KA+ ER L
Sbjct: 1516 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Query: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
+DE+ E+ K+ +R V ++ L+ E + R+ A+ +KK+E DL ++E + AN+ E
Sbjct: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
Query: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
A KQ++ LQ+ +KD +LDD + +++ E++ ++AE+ +L+ + ER+
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
++ A+QE E ++ + + + +K++++A ++QL+ E+EE ++ KKA
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
+ +L E+ + E ++ +E+ K+L+ +L E E K + LEA+
Sbjct: 1756 NLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815
Query: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
+ +LE +L+ E K + K +R++E+++K++ Q +++R+N + +D DK ++K
Sbjct: 1816 IAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQL 1875
Query: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
KRQ EEAEE+A + RK+Q EL++A E AD +V+ L+ K R
Sbjct: 1876 KRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 260 bits (665), Expect = 8e-69
Identities = 239/989 (24%), Positives = 456/989 (46%), Gaps = 111/989 (11%)
Query: 845 REKEMASMKEEFTRLKEALEK--SEARRKELEEKMV-------SLLQEKNDLQLQVQAEQ 895
+E E +EE R K LEK +EA+ K+LEE+ + L +EK L+ ++
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 896 DNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE-------DECS 948
NL + EE+ L K K + EA + ++ ERL EE+ EL +RKLE D+ +
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 949 ELKRDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDEIIAK--- 991
EL+ I +L++ LAK E+E K+ K++ L +++ L E +
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 992 -----------LTKEKKALQEAHQQALDDLQAE-------EDKVNTLTKA---------- 1023
L +E +AL+ + LD A+ E +VN L K
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEA 1185
Query: 1024 -----KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
+ K Q V++L LEQ K+V+ +LE+AK+ LE + + L K +
Sbjct: 1186 QIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEH 1245
Query: 1079 RLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD 1138
+ KK + +L L + + + + ++L K+ +LQ ++ + L + +K+ K S
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSA 1305
Query: 1139 LSRELEEISERLEEAGGAT--------SVQIEMNKKREA--EFQKMRRDLEEATLQHEAT 1188
L +L++ E L+E V+ E N RE E ++ + +LE+ A
Sbjct: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQ 1365
Query: 1189 AAALRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEKEKSEFKLELDDV 1231
A ++KK DSV E E++ +L+ + Q KLEK K+ + ELDD+
Sbjct: 1366 VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL 1425
Query: 1232 TSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL 1291
+++ ++ NLEK + + + E ++ + + + ++ + +T+ L+R L
Sbjct: 1426 LVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARAL 1485
Query: 1292 DEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEET 1351
+E ++L R + ++EDL ++ K+ + L + ++ + ++ Q EE
Sbjct: 1486 EEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
Query: 1352 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKC 1411
+ + + + + ++E D R E+ EE KK+L ++++E E +E +
Sbjct: 1546 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 1605
Query: 1412 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD-------KILAEWKQKYEESQ 1464
S + +L+ +++DL ++ +N K+ R + L + + EE
Sbjct: 1606 SMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEIL 1665
Query: 1465 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH 1524
++ + ++K+ +S+ E+ +L +E L E KR+ + ++E++D E SSGK
Sbjct: 1666 AQAKENEKKLKSMEAEMIQL----QEELAAAERAKRQAQQERDELAD--EIANSSGKGAL 1719
Query: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEE 1582
LE+ R+ LEA +L+ LEE + + E ++ +A L+ +QI ++ ER A+K+E
Sbjct: 1720 ALEEKRR-LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 1583 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1642
Q + + ++ +S+ +A +E + ++E QL + + A KQ
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITA--LEAKIAQLEEQLDNETKERQAACKQ 1836
Query: 1643 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
V+ + LKD +Q+DD R + K+ R L+ +LEE ++ SR+
Sbjct: 1837 VRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKL 1896
Query: 1703 EQELIETSERVQLLHSQNTSLINQKKKMD 1731
++EL + +E ++ + +SL N+ ++ D
Sbjct: 1897 QRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 232 bits (592), Expect = 2e-60
Identities = 212/983 (21%), Positives = 451/983 (45%), Gaps = 96/983 (9%)
Query: 993 TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
TK K LQ + Q+ +++ A+E+++ VK+ ++ E L + + ++ L K
Sbjct: 832 TKVKPLLQVSRQE--EEMMAKEEEL-------VKVREKQLAAENRLTEMETLQSQLMAEK 882
Query: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQ 1112
+L+ L+ E + E + +L + ++ + + L AR+E+E+ LQ + K++Q
Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 1113 ARIEELEEELEAERTARAKV--EKLRSDLS-RELEEISERLEEAGGATSVQIEMNKKREA 1169
I+ELEE+LE E +AR K+ EK+ ++ ++LEE LE+ + + ++ + R A
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 1170 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
EF + EE + + A L+ KH + +L E++ ++ +Q+LEK + + + +
Sbjct: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 1230 DVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSR 1289
D++ + ++ A L+ E+++ ++ EE N + +L+++ EL
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 1290 QLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
L+ + A +R K E KR L EE++A L+ + E+
Sbjct: 1119 DLESERA-----SRNKA------EKQKRDLGEELEA-----------------LKTELED 1150
Query: 1350 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNA 1409
++ A Q + SK EV + E +A +++E ++K +Q ++E E +E
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
Query: 1410 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1469
++LEK K L+NE +L +V+ + K++ + L E + K+ E +
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
Query: 1470 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV 1529
+ L EL + +S ++ L+ ++ D E L + L
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 1530 RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1589
KQ+E EK + LEE E + + E +I + +K ++E + E E+ KR
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389
Query: 1590 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 1649
+ ++ L + + + ++ + K +++ +L+++ + L H + A +K+ K L
Sbjct: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
Query: 1650 L---------------------KDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1688
L ++ + + RA ++ E A +ER N + E+E+L
Sbjct: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509
Query: 1689 RAV-------VEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
+ V + E+S++ EQ++ E +++ L + + + K +++ +L ++ +
Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQF 1569
Query: 1742 EEAVQ-ECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEA 1800
E +Q +EEK K+ + M EL+ E+ + +K +E +KDL+ +D A
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629
Query: 1801 EQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKN 1860
+ + KQL+KL+A++++ EL+ + E + +++E+++K + +
Sbjct: 1630 NKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE------- 1681
Query: 1861 LLRLQD-LVDKLQLKVKAYKRQAEEAEEQANTN-------------LSKFRKVQHELDEA 1906
+++LQ+ L + K +A + + E A+E AN++ ++ +++ EL+E
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1741
Query: 1907 EERADIAESQVNKLRAKSRDIGT 1929
+ ++ ++ K + I T
Sbjct: 1742 QGNTELINDRLKKANLQIDQINT 1764
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 1422 bits (3682), Expect = 0.0
Identities = 788/1908 (41%), Positives = 1177/1908 (61%), Gaps = 27/1908 (1%)
Query: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
KK V++P ++ F A I G +V E E GK V +D + + NPPKF K+EDMA
Sbjct: 33 KKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAE 92
Query: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
LT L+E +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ ++ YRGKKR E PP
Sbjct: 93 LTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPP 152
Query: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
HI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K PG
Sbjct: 153 HIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPG 212
Query: 213 KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272
+ LE Q++QANP LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR
Sbjct: 213 E--LERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSR 270
Query: 273 VIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASIDDAEELM 330
+ Q K ER +HIFYQ+LS L LL+ NN Y F+S G + D +
Sbjct: 271 AVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNN---YRFLSNGYIPIPGQQDKDNFQ 327
Query: 331 ATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGL 390
T A ++GF+ EE SM K+ +++ FGN+ FK ++ +QA A K +L+G+
Sbjct: 328 ETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGM 387
Query: 391 NSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-T 449
N + + + PR+KVG +YV K Q +Q +A ALAKA YER+F W+V RIN L+ T
Sbjct: 388 NVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRT 447
Query: 450 KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 509
K+ FIG+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 448 KRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507
Query: 510 FIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
FIDFG+DLQ CIDLIE+P G++++L+EEC FPKATD TF KL G + FQKP
Sbjct: 508 FIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKP 566
Query: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY-- 624
R +K K A F +IHYAG VDY WL KN DPLN+ V L +SS + ++ L+ +
Sbjct: 567 RQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR 624
Query: 625 -AGAD---APIEKGKG---KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677
G D E G K KKG F+TV L++E+L KLM LR+T+P+FVRCIIPN
Sbjct: 625 IVGLDQVTGMTETAFGSAYKTKKGM-FRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNH 683
Query: 678 TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737
K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL P AIP+G F+D
Sbjct: 684 EKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMD 742
Query: 738 SRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLA 797
++ E+++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA RG LA
Sbjct: 743 GKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLA 802
Query: 798 RMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFT 857
R + K ++ +L V+Q N A++ +++W W +++ K+KPLL+ +E+E+ + EE
Sbjct: 803 RKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELL 862
Query: 858 RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
++KE K E +E+E K LL+EKN L Q+QAE + A+AEE +L K +LE
Sbjct: 863 KVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEE 922
Query: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
+ ++ R+E+EEE N L +K+K++ +L+ +D+ E K++ EK E K+K
Sbjct: 923 ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKK 982
Query: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGS 1037
+ EE+ L++ +K KEKK +++ + L EE+K L K + K E + DLE
Sbjct: 983 MEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEER 1042
Query: 1038 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDE 1097
L++E+K R +LE+AKRKL+G+ Q+ I +L+ +L +L KK+ EL AR +DE
Sbjct: 1043 LKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDE 1102
Query: 1098 QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1157
+ K ++ELQA+I EL+E+ E+E+ +R K EK + DLS ELE + LE+ T
Sbjct: 1103 TLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTT 1162
Query: 1158 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217
+ Q E+ KRE E ++++ LEE T HEA +R++HA ++ EL EQ++ +R K L
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1222
Query: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
EK K + + ++ ++ + + KA E + L+ Q+ E +K E R +L +
Sbjct: 1223 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
Query: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
+KLQ E +S L+E E + + + QL+D + L+EE + K L+ ++
Sbjct: 1283 SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLE 1342
Query: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
+ + L+EQ EEE EA+ L++ + S++A + K + D + E LEEAKKKL +
Sbjct: 1343 EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKKLLKDA 1401
Query: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1457
+ + +E LEKTK+RLQ E++DL VD++ A+ L+KKQ+ FD++LAE K
Sbjct: 1402 EALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEK 1461
Query: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
E + ++ EAR T+ L A EE+LE E F+R+NK L+ ++ DL
Sbjct: 1462 SISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKD 1521
Query: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
GK +HELEK ++ LE + E+++ LEE E L+ E LR ++ +KA+ ER L
Sbjct: 1522 DVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQ 1581
Query: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
+DE+ E+ KR ++ V L+ L+ E + R A+ KKKME DL ++E Q+ AN+
Sbjct: 1582 TRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
Query: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
E KQ++ LQ+ +KD Q +L++A + D++ E++ L+AE+ +L+ + +ER
Sbjct: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
Query: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757
+R+ AEQE E ++ + S ++L+++K++++A ++QL+ E+EE ++ +K
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761
Query: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1817
+ EL E+ + + ++ +E+ K+L+ +L E E K + LEA
Sbjct: 1762 TTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEA 1821
Query: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
++ +LE +LE E K A + K +R++E+++KE+ Q E++R++ + ++ ++K ++K
Sbjct: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881
Query: 1878 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
KRQ EEAEE+A + RK+Q ELD+A E + +V+ L+ + R
Sbjct: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
Score = 254 bits (648), Expect = 7e-67
Identities = 232/987 (23%), Positives = 459/987 (46%), Gaps = 127/987 (12%)
Query: 853 KEEFTRLKEALEK--SEARRKELEEKMVSL-------LQEKNDLQLQVQAEQDNLADAEE 903
+EE R K LEK +EA+ K++EE+++ L ++EK ++ ++ LA+ EE
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 904 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE-------DECSELKRDIDD 956
+ L K + + E + ++ ERL+ EE+ EL KRKL+ D+ +EL+ ID+
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Query: 957 LELTLAKVEKEKHAT-----------ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
L+L LAK E+E N +K + E A + E+ EK + +A +Q
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
Query: 1006 A------LDDLQAE-EDKVNTLT---KAKVKLEQQVDDLEGSLEQE-------------- 1041
L+ L+ E ED ++T + + K EQ+V +L+ +LE+E
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
Query: 1042 ---------------KKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
K+ + +LE+ K+ LE D K + L+ K + + + KK D +
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
Query: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
+ L+A++ + L +L +K +LQ ++ + LE K K + L +L++
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Query: 1147 SERLEEAGGAT---SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1203
E L+E S +I ++ + Q+ + + EEA E AL+ + AD+ ++
Sbjct: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Query: 1204 GEQIDNLQRVKQ------------------------KLEKEKSEFKLELDDVTSNMEQII 1239
+ + ++ +++ KLEK K+ + ELDD+T +++
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
Query: 1240 KAKANLEKMCRTLEDQMNEHRS----KAEETQRSVNDLTSQRAKLQTENGELSRQLDEKE 1295
+ +NLEK + + + E +S AEE R+ + + K + L L+ KE
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
Query: 1296 ALI---SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETE 1352
QL +D+ + + E K+K AL ++ R + L ++ + +
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560
Query: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCS 1412
AK L+ + + ++E D R E+ EE K+ L ++++E E +E + +
Sbjct: 1561 AKLRLE-------VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA 1613
Query: 1413 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQS------- 1465
+K +++ +++DL +E +N A + K+ R + +++++ EE+++
Sbjct: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFA 1673
Query: 1466 ELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHE 1525
+ + S+K+ +SL E+ +L+ E L + +R ++ ++E +L +++ +S
Sbjct: 1674 QSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQERDELADEITNSASGKSA 1726
Query: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEK-DEE 1582
L +++LEA +L+ LEE ++++E + + L+ + + AE+ ER A+K D
Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA 1786
Query: 1583 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1642
+Q +R + + LQ L+ +S+ +A +E + ++E QL + A A K
Sbjct: 1787 RQQLERQNKELKAKLQ-ELEGAVKSKFKA--TISALEAKIGQLEEQLEQEAKERAAANKL 1843
Query: 1643 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
V+ + LK+ +Q++D R D KE + R L+ +LEE + SR+
Sbjct: 1844 VRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKL 1903
Query: 1703 EQELIETSERVQLLHSQNTSLINQKKK 1729
++EL + +E + L + ++L N+ ++
Sbjct: 1904 QRELDDATEANEGLSREVSTLKNRLRR 1930
Score = 192 bits (487), Expect = 3e-48
Identities = 186/888 (20%), Positives = 395/888 (44%), Gaps = 99/888 (11%)
Query: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136
+E L+ KD EL + + + ++++K ++L L E+L+AE A+ E++R
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1196
+ L+ + +E+ E L + + E N+ + E +KM+ +++
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD---------------- 954
Query: 1197 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQM 1256
L EQ+D + +QKL+ EK + ++ + + + + K + +ED++
Sbjct: 955 ------LEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRI 1008
Query: 1257 NEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLK 1316
E S+ E + +L R K + +L +L ++E +L + K + DL+
Sbjct: 1009 AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
Query: 1317 RQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1376
Q+ E LQ+ + L + EEE LQ L++ + E T ++
Sbjct: 1069 DQIAE-----------LQAQIDELKLQLAKKEEE------LQGALARGDDE-----TLHK 1106
Query: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
+A++ EL+ ++ E +E E+ A + EK K L E+E L ++E +
Sbjct: 1107 NNALKVVRELQA-------QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
AA + + ++ +AE K+ EE E+ ++ R + A EE E LE
Sbjct: 1160 DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ------RHATALEELSEQLE 1213
Query: 1497 TFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG 1556
KR NL++ L + L++V+ + E ++ +L + ++E A + EG
Sbjct: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EG 1271
Query: 1557 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRV----------VDSLQTSLDAETR 1606
LR +L + ++++ +L +E+A++ ++ + Q L ETR
Sbjct: 1272 DRLRVELA--EKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETR 1329
Query: 1607 SRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD 1666
+ +++E + N ++ Q +KQV +LQS L DT+ ++DD + +
Sbjct: 1330 QKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIES 1389
Query: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
L+E + + L LEE ++ E+++ +QEL + + + ++L +
Sbjct: 1390 LEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK 1449
Query: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM 1786
+KK D L++ ++ +E AE +A++ T A +A L++ + ER K +
Sbjct: 1450 QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL 1509
Query: 1787 EQTIKDLQHRLDEAE------QIALKGGKKQLQKLEARVRELENELEAE----------- 1829
++DL D+ + + + ++Q++++ ++ ELE+EL+A
Sbjct: 1510 RADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNM 1569
Query: 1830 -----------QKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Q R+ ++ + R ++++EL + E++RK K+++ +K
Sbjct: 1570 QAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDL 1629
Query: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRD 1926
+ Q E A + + + + RK+Q ++ + + + A + +++ A+S++
Sbjct: 1630 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Score = 80.1 bits (196), Expect = 2e-14
Identities = 82/323 (25%), Positives = 148/323 (45%), Gaps = 43/323 (13%)
Query: 1610 EALRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD 1666
E L+VK+K +EG+L EME + Q LL++ I L + ++A +
Sbjct: 860 ELLKVKEKQTKVEGELEEME-----------------RKHQQLLEEKNI-LAEQLQAETE 901
Query: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
L AE EE+RA + ++ E+ L + RV+ +N L N+
Sbjct: 902 LF--------------AEAEEMRA---RLAAKKQELEEILHDLESRVEEEEERNQILQNE 944
Query: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKK 1784
KKKM A + L+ +++E +E + + +K +A + M EE+ +D ++ + KK
Sbjct: 945 KKKMQAHIQDLEEQLDE--EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
Query: 1785 NMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSE 1844
ME I + +L E E+ A K K K E + +LE L+ E+K E K RK +
Sbjct: 1003 LMEDRIAECSSQLAEEEEKA-KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061
Query: 1845 RRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELD 1904
+L Q E + + L+ + K + +++ + ++ N L R++Q ++
Sbjct: 1062 GETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIA 1121
Query: 1905 EAEERADIAESQVNKLRAKSRDI 1927
E +E + ++ NK + RD+
Sbjct: 1122 ELQEDFESEKASRNKAEKQKRDL 1144
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 1318 bits (3411), Expect = 0.0
Identities = 735/1907 (38%), Positives = 1155/1907 (60%), Gaps = 34/1907 (1%)
Query: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93
V+VP + F A + R+ G+ AE E G+ + + DQ+ + NPPKF K EDMA L
Sbjct: 56 VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113
Query: 94 TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153
T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT +V YRGKKR E PPH
Sbjct: 114 TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173
Query: 154 IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213
++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K+ PG+
Sbjct: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGE 233
Query: 214 GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRV 273
LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 234 --LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRA 291
Query: 274 IFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATD 333
I Q K E +HIFYQ+L +L LL+ + Y F++ G ++ + E T
Sbjct: 292 IRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETL 349
Query: 334 NAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSA 393
+ VLGF+ EE SM ++ A++ FGN+ K ++ +QA A K L+GL
Sbjct: 350 ESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVT 409
Query: 394 DLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPR 453
D + L PR+KVG +YV K Q +Q +A ALAKA YER+F W+V R+N L+ + PR
Sbjct: 410 DFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPR 468
Query: 454 Q--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFI 511
Q F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+
Sbjct: 469 QGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFL 528
Query: 512 DFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRN 568
DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G FQ+PR+
Sbjct: 529 DFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRH 587
Query: 569 IKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAG-- 626
++ +A FS++HYAG VDY WL KN DPLN+ V L +S+ +L + ++ + G
Sbjct: 588 LRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645
Query: 627 --------ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNET 678
D P G+ ++G F+TV L++E+L++LM L +T+P FVRCI+PN
Sbjct: 646 GLEQVSSLGDGP---PGGRPRRGM-FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHE 701
Query: 679 KSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDS 738
K G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+G F+D
Sbjct: 702 KRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDG 760
Query: 739 RKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLAR 798
++ EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA +RG LAR
Sbjct: 761 KQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLAR 820
Query: 799 MEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858
++K +++ +L V+Q N A++ +++W W +L+ K+KPLL+ +++ + + +E +
Sbjct: 821 RAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQK 880
Query: 859 LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAK 918
++E ++S EL+ ++ L +E+ L Q++AE + A+AEE +L K +LE
Sbjct: 881 VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940
Query: 919 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978
V E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K
Sbjct: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000
Query: 979 TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSL 1038
E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E L
Sbjct: 1001 EEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRL 1060
Query: 1039 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQ 1098
+E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ EL A AR EDE
Sbjct: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120
Query: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
+QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+ +T+
Sbjct: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180
Query: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Q E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K E
Sbjct: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240
Query: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278
K + + E+ ++ + + + A+ E+ R LE Q+ E + +A + +R+ + +
Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300
Query: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338
+ Q E +S L+E E+ +L++ + QL D + L+EE +AK AL +++
Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360
Query: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398
+ LREQ EEE A+ R L A +++++WR + E +A E EEA+++ A+ +
Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAE 1419
Query: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458
+ + LE+ + RLQ E++D +D+E+ + L+KKQR FD++LAE K
Sbjct: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479
Query: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518
+ E E ++ E R L A EE E E +R+N+ L+ E+ L
Sbjct: 1480 AVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDD 1539
Query: 1519 SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1578
GK++HELE+ + E +L++ + E E L E LR ++ +K + ER L
Sbjct: 1540 VGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQG 1599
Query: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
+DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++ A + E
Sbjct: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659
Query: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
A KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ + ++R+
Sbjct: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719
Query: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
R+ A+Q+ E ++ V + +++ +K++++ L QL+ E+EE ++ +K
Sbjct: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779
Query: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
+ + EL E+ SA E ++ +E+ I++L+ RL E + A K + LE++
Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839
Query: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
+ + E +LE E + S K +R++E+R+KE+ Q EE+R+ +L+D ++K L+VK
Sbjct: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899
Query: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
KRQ EEAEE+A+ + R++Q EL++ E A+ +V LR + R
Sbjct: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946
Score = 231 bits (590), Expect = 4e-60
Identities = 239/1097 (21%), Positives = 475/1097 (43%), Gaps = 122/1097 (11%)
Query: 769 LLGLLEEMRDERLSRIITRIQAQSRGVLARMEYK-KLLERRDSLLVIQWNIRAFMGVKNW 827
L G + ++ +ER +R+ +++A++ E + +L R+ L ++ + A +G +
Sbjct: 895 LQGRVAQLEEER-ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEE 953
Query: 828 PWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEK--SEARRKELEEKMVSLLQEKN 885
++ + K L + + E E EE R K LEK +EA+ K+ EE ++ L + +
Sbjct: 954 CSRQMQTEKKRLQQHIQ-ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1012
Query: 886 DLQLQVQAEQDNLAD-------AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 938
L + + +D LA+ EE+ L K +++ EA + +M +RL EE+ EL
Sbjct: 1013 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1072
Query: 939 KKRKLEDECSELKRDI------------------DDLELTLAKVEKEKHATENKVKNLTE 980
KR+L+ E SEL+ + ++L+ LA+ E E A +K+L E
Sbjct: 1073 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1132
Query: 981 EMAGLDEIIAKLTKEKKALQEAHQQALD----------DLQAEEDKVNTLTKAKVKLEQQ 1030
A L E L E+ A +A +Q D +L+ D N + + K EQ+
Sbjct: 1133 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1192
Query: 1031 VDDLEGSLEQEKKVRM-------------------DLERAKR----------KLEGDLKL 1061
V +L+ +LE+E ++ LE+A+R LE ++
Sbjct: 1193 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1252
Query: 1062 TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEE 1121
+ + L+ +Q+ ++R ++ + +L + R D + ++ +KL+ QA +E +
Sbjct: 1253 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1312
Query: 1122 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
L + ++ K S +L + E L+E A + EAE +R LEE
Sbjct: 1313 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1372
Query: 1182 TLQHEATAAAL------------RKKHADSVAELGEQIDN---------LQRVKQK---- 1216
E L R++ E GE+ QR+ +K
Sbjct: 1373 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1432
Query: 1217 --LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSV 1270
LE+ + + ELDD T ++EQ + + LEK R + + E ++ EE +R+
Sbjct: 1433 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1492
Query: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
+ + A+ + L+R L+E++ +L R +LE L ++ K+ + L
Sbjct: 1493 AEGREREARALS----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELE 1548
Query: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
A + A + LR Q E + + + V +T++E D R E EE +
Sbjct: 1549 RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1608
Query: 1391 KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
++LA++L++AE + + + + +L+ E+E+L + + K+ R
Sbjct: 1609 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1668
Query: 1451 KILAEWKQKYEESQSELES-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503
+ E ++ EE+++ E S+K + L E+ +L+ E L R +
Sbjct: 1669 AQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARR 1721
Query: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
Q++ ++ +++ + + + + ++QLE +L+ LEE +++ E + + L
Sbjct: 1722 QAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLL 1781
Query: 1564 EFNQIKAEI--ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGD 1621
+ + E+ ER + K E Q ++ + DA R+R++ +E
Sbjct: 1782 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESK 1839
Query: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
L + E QL R + K V+ + LK+ +Q+++ R D L++ + R L
Sbjct: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899
Query: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
+ +LEE + + R+ ++EL + +E + ++ + T+L N+ ++ +
Sbjct: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQ 1959
Query: 1742 EEAVQECRNAEEKAKKA 1758
++E ++E+A++A
Sbjct: 1960 VFRLEEGVASDEEAEEA 1976
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%)
Query: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 933
Query: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
+EL VV + E ++ E+E E S ++Q +KK++ + +L+ +E
Sbjct: 934 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 977
Query: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 978 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1037
Query: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
+K K K EA + ++E+ L E+K E K R+ + EL Q E ++
Sbjct: 1038 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1096
Query: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1097 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1156
Query: 1923 KSRDIG 1928
+ RD+G
Sbjct: 1157 QRRDLG 1162
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 1316 bits (3405), Expect = 0.0
Identities = 735/1913 (38%), Positives = 1154/1913 (60%), Gaps = 38/1913 (1%)
Query: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93
V+VP + F A + R+ G+ AE E G+ + + DQ+ + NPPKF K EDMA L
Sbjct: 56 VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113
Query: 94 TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153
T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT +V YRGKKR E PPH
Sbjct: 114 TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173
Query: 154 IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213
++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K+ P
Sbjct: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
Query: 214 ------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
Query: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327
LEKSR I Q K E +HIFYQ+L +L LL+ + Y F++ G ++ + E
Sbjct: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
Query: 328 ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387
T + VLGF+ EE SM ++ A++ FGN+ K ++ +QA A K L
Sbjct: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
Query: 388 MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447
+GL D + L PR+KVG +YV K Q +Q +A ALAKA YER+F W+V R+N L
Sbjct: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
Query: 448 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 505
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
Query: 506 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSAN 562
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
Query: 563 FQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFA 622
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V L +S+ +L + ++
Sbjct: 590 FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
Query: 623 NYAG----------ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRC 672
+ G D P G+ ++G F+TV L++E+L++LM L +T+P FVRC
Sbjct: 648 DVEGIVGLEQVSSLGDGP---PGGRPRRGM-FRTVGQLYKESLSRLMATLSNTNPSFVRC 703
Query: 673 IIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPE 732
I+PN K G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+
Sbjct: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
Query: 733 GQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQS 792
G F+D ++ EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA +
Sbjct: 764 G-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 822
Query: 793 RGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASM 852
RG LAR ++K +++ +L V+Q N A++ +++W W +L+ K+KPLL+ +++ + +
Sbjct: 823 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 882
Query: 853 KEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNK 912
+E +++E ++S EL+ ++ L +E+ L Q++AE + A+AEE +L K
Sbjct: 883 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 942
Query: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
+LE V E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE
Sbjct: 943 QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1002
Query: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
K+K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E +
Sbjct: 1003 AKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIA 1062
Query: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNA 1092
D+E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ EL A A
Sbjct: 1063 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
Query: 1093 RIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE 1152
R EDE +QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+
Sbjct: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182
Query: 1153 AGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR 1212
+T+ Q E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R
Sbjct: 1183 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242
Query: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND 1272
K EK + + E+ ++ + + + A+ E+ R LE Q+ E + +A + +R+ +
Sbjct: 1243 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1302
Query: 1273 LTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHA 1332
+ + Q E +S L+E E+ +L++ + QL D + L+EE +AK AL
Sbjct: 1303 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
Query: 1333 LQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1392
+++ + LREQ EEE A+ R L A +++++WR + E +A E EEA+++
Sbjct: 1363 VRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRR 1421
Query: 1393 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452
A+ + + + LE+ + RLQ E++D +D+E+ + L+KKQR FD++
Sbjct: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
Query: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
LAE K + E E ++ E R L A EE E E +R+N+ L+ E+ L
Sbjct: 1482 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
Query: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
GK++HELE+ + E +L++ + E E L E LR ++ +K +
Sbjct: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
Query: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
ER L +DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++ A
Sbjct: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
Query: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
+ EA KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ +
Sbjct: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1721
Query: 1693 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
++R+R+ A+Q+ E ++ V + +++ +K++++ L QL+ E+EE
Sbjct: 1722 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1781
Query: 1753 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQL 1812
++ +K + + EL E+ SA E ++ +E+ I++L+ RL E + A K +
Sbjct: 1782 DRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTI 1841
Query: 1813 QKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQ 1872
LE+++ + E +LE E + S K +R++E+R+KE+ Q EE+R+ +L+D ++K
Sbjct: 1842 AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGN 1901
Query: 1873 LKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
L+VK KRQ EEAEE+A+ + R++Q EL++ E A+ +V LR + R
Sbjct: 1902 LRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
Score = 231 bits (590), Expect = 4e-60
Identities = 239/1097 (21%), Positives = 475/1097 (43%), Gaps = 122/1097 (11%)
Query: 769 LLGLLEEMRDERLSRIITRIQAQSRGVLARMEYK-KLLERRDSLLVIQWNIRAFMGVKNW 827
L G + ++ +ER +R+ +++A++ E + +L R+ L ++ + A +G +
Sbjct: 903 LQGRVAQLEEER-ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEE 961
Query: 828 PWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEK--SEARRKELEEKMVSLLQEKN 885
++ + K L + + E E EE R K LEK +EA+ K+ EE ++ L + +
Sbjct: 962 CSRQMQTEKKRLQQHIQ-ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1020
Query: 886 DLQLQVQAEQDNLAD-------AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 938
L + + +D LA+ EE+ L K +++ EA + +M +RL EE+ EL
Sbjct: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1080
Query: 939 KKRKLEDECSELKRDI------------------DDLELTLAKVEKEKHATENKVKNLTE 980
KR+L+ E SEL+ + ++L+ LA+ E E A +K+L E
Sbjct: 1081 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1140
Query: 981 EMAGLDEIIAKLTKEKKALQEAHQQALD----------DLQAEEDKVNTLTKAKVKLEQQ 1030
A L E L E+ A +A +Q D +L+ D N + + K EQ+
Sbjct: 1141 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1200
Query: 1031 VDDLEGSLEQEKKVRM-------------------DLERAKR----------KLEGDLKL 1061
V +L+ +LE+E ++ LE+A+R LE ++
Sbjct: 1201 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1260
Query: 1062 TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEE 1121
+ + L+ +Q+ ++R ++ + +L + R D + ++ +KL+ QA +E +
Sbjct: 1261 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1320
Query: 1122 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
L + ++ K S +L + E L+E A + EAE +R LEE
Sbjct: 1321 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380
Query: 1182 TLQHEATAAAL------------RKKHADSVAELGEQIDN---------LQRVKQK---- 1216
E L R++ E GE+ QR+ +K
Sbjct: 1381 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1440
Query: 1217 --LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSV 1270
LE+ + + ELDD T ++EQ + + LEK R + + E ++ EE +R+
Sbjct: 1441 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1500
Query: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
+ + A+ + L+R L+E++ +L R +LE L ++ K+ + L
Sbjct: 1501 AEGREREARALS----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELE 1556
Query: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
A + A + LR Q E + + + V +T++E D R E EE +
Sbjct: 1557 RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1616
Query: 1391 KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
++LA++L++AE + + + + +L+ E+E+L + + K+ R
Sbjct: 1617 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1676
Query: 1451 KILAEWKQKYEESQSELES-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503
+ E ++ EE+++ E S+K + L E+ +L+ E L R +
Sbjct: 1677 AQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARR 1729
Query: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
Q++ ++ +++ + + + + ++QLE +L+ LEE +++ E + + L
Sbjct: 1730 QAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLL 1789
Query: 1564 EFNQIKAEI--ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGD 1621
+ + E+ ER + K E Q ++ + DA R+R++ +E
Sbjct: 1790 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESK 1847
Query: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
L + E QL R + K V+ + LK+ +Q+++ R D L++ + R L
Sbjct: 1848 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1907
Query: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
+ +LEE + + R+ ++EL + +E + ++ + T+L N+ ++ +
Sbjct: 1908 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQ 1967
Query: 1742 EEAVQECRNAEEKAKKA 1758
++E ++E+A++A
Sbjct: 1968 VFRLEEGVASDEEAEEA 1984
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%)
Query: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 941
Query: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
+EL VV + E ++ E+E E S ++Q +KK++ + +L+ +E
Sbjct: 942 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 985
Query: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 986 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1045
Query: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
+K K K EA + ++E+ L E+K E K R+ + EL Q E ++
Sbjct: 1046 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1104
Query: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1105 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1164
Query: 1923 KSRDIG 1928
+ RD+G
Sbjct: 1165 QRRDLG 1170
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 1306 bits (3379), Expect = 0.0
Identities = 735/1943 (37%), Positives = 1156/1943 (59%), Gaps = 65/1943 (3%)
Query: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93
V+VP + F A + R+ G+ AE E G+ + + DQ+ + NPPKF K EDMA L
Sbjct: 56 VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113
Query: 94 TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153
T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT +V YRGKKR E PPH
Sbjct: 114 TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173
Query: 154 IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213
++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K+ P
Sbjct: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
Query: 214 ------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
Query: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327
LEKSR I Q K E +HIFYQ+L +L LL+ + Y F++ G ++ + E
Sbjct: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
Query: 328 ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387
T + VLGF+ EE SM ++ A++ FGN+ K ++ +QA A K L
Sbjct: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
Query: 388 MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447
+GL D + L PR+KVG +YV K Q +Q +A ALAKA YER+F W+V R+N L
Sbjct: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
Query: 448 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 505
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
Query: 506 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSAN 562
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
Query: 563 FQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFA 622
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V L +S+ +L + ++
Sbjct: 590 FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
Query: 623 N---------YAGADAPIEKGK-------------------------------GKAKKGS 642
+ + G+ P G G+ ++G
Sbjct: 648 DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
Query: 643 SFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGI 702
F+TV L++E+L++LM L +T+P FVRCI+PN K G ++ LV+ QLRCNGVLEGI
Sbjct: 708 -FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGI 766
Query: 703 RICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTK 762
RICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++ EK++ +L++D N Y+ G +K
Sbjct: 767 RICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSK 825
Query: 763 VFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFM 822
+FF+AG+L LEE RD +++ II QA +RG LAR ++K +++ +L V+Q N A++
Sbjct: 826 IFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYL 885
Query: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
+++W W +L+ K+KPLL+ +++ + + +E +++E ++S EL+ ++ L +
Sbjct: 886 KLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEE 945
Query: 883 EKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942
E+ L Q++AE + A+AEE +L K +LE V E+ R+ +EEE + ++ +K++
Sbjct: 946 ERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKR 1005
Query: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002
L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++
Sbjct: 1006 LQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR 1065
Query: 1003 HQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
+ EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1066 LAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSEL 1125
Query: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
QE +++ + ++L +L +K+ EL A AR EDE +QL K L+E QA + E +E+L
Sbjct: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
Query: 1123 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1182
E+ER AR K EK R DL ELE + LE+ +T+ Q E+ KRE E ++++ LEE T
Sbjct: 1186 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEET 1245
Query: 1183 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1242
HEA LR++H ++ EL EQ++ +R K EK + + E+ ++ + + + A+
Sbjct: 1246 RIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTAR 1305
Query: 1243 ANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT 1302
E+ R LE Q+ E + +A + +R+ + + + Q E +S L+E E+ +L+
Sbjct: 1306 QEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLS 1365
Query: 1303 RGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLS 1362
+ + QL D + L+EE +AK AL +++ + LREQ EEE A+ R L
Sbjct: 1366 KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 1425
Query: 1363 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQ 1422
A +++++WR + E +A E EEA+++ A+ + + + LE+ + RLQ
Sbjct: 1426 TAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1484
Query: 1423 NEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELF 1482
E++D +D+E+ + L+KKQR FD++LAE K + E E ++ E R
Sbjct: 1485 QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARAL 1544
Query: 1483 KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQS 1542
L A EE E E +R+N+ L+ E+ L GK++HELE+ + E +L++
Sbjct: 1545 SLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRA 1604
Query: 1543 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLD 1602
+ E E L E LR ++ +K + ER L +DE E+ +R + + + D
Sbjct: 1605 QVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERD 1664
Query: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR 1662
E + R A+ +KK+EG+L E++ Q++ A + EA KQ++ +Q+ +K+ ++++
Sbjct: 1665 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRT 1724
Query: 1663 ANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTS 1722
+ +++ E+R L+AE+ L+ + ++R+R+ A+Q+ E ++ V + +
Sbjct: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
Query: 1723 LINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1782
++ +K++++ L QL+ E+EE ++ +K + + EL E+ SA E
Sbjct: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1844
Query: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
++ +E+ I++L+ RL E + A K + LE+++ + E +LE E + S K +R+
Sbjct: 1845 RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRR 1904
Query: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
+E+R+KE+ Q EE+R+ +L+D ++K L+VK KRQ EEAEE+A+ + R++Q E
Sbjct: 1905 AEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1964
Query: 1903 LDEAEERADIAESQVNKLRAKSR 1925
L++ E A+ +V LR + R
Sbjct: 1965 LEDVTESAESMNREVTTLRNRLR 1987
Score = 231 bits (590), Expect = 4e-60
Identities = 239/1097 (21%), Positives = 475/1097 (43%), Gaps = 122/1097 (11%)
Query: 769 LLGLLEEMRDERLSRIITRIQAQSRGVLARMEYK-KLLERRDSLLVIQWNIRAFMGVKNW 827
L G + ++ +ER +R+ +++A++ E + +L R+ L ++ + A +G +
Sbjct: 936 LQGRVAQLEEER-ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEE 994
Query: 828 PWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEK--SEARRKELEEKMVSLLQEKN 885
++ + K L + + E E EE R K LEK +EA+ K+ EE ++ L + +
Sbjct: 995 CSRQMQTEKKRLQQHIQ-ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1053
Query: 886 DLQLQVQAEQDNLAD-------AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 938
L + + +D LA+ EE+ L K +++ EA + +M +RL EE+ EL
Sbjct: 1054 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1113
Query: 939 KKRKLEDECSELKRDI------------------DDLELTLAKVEKEKHATENKVKNLTE 980
KR+L+ E SEL+ + ++L+ LA+ E E A +K+L E
Sbjct: 1114 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1173
Query: 981 EMAGLDEIIAKLTKEKKALQEAHQQALD----------DLQAEEDKVNTLTKAKVKLEQQ 1030
A L E L E+ A +A +Q D +L+ D N + + K EQ+
Sbjct: 1174 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1233
Query: 1031 VDDLEGSLEQEKKVRM-------------------DLERAKR----------KLEGDLKL 1061
V +L+ +LE+E ++ LE+A+R LE ++
Sbjct: 1234 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1293
Query: 1062 TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEE 1121
+ + L+ +Q+ ++R ++ + +L + R D + ++ +KL+ QA +E +
Sbjct: 1294 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1353
Query: 1122 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
L + ++ K S +L + E L+E A + EAE +R LEE
Sbjct: 1354 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1413
Query: 1182 TLQHEATAAAL------------RKKHADSVAELGEQIDN---------LQRVKQK---- 1216
E L R++ E GE+ QR+ +K
Sbjct: 1414 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1473
Query: 1217 --LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSV 1270
LE+ + + ELDD T ++EQ + + LEK R + + E ++ EE +R+
Sbjct: 1474 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1533
Query: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
+ + A+ + L+R L+E++ +L R +LE L ++ K+ + L
Sbjct: 1534 AEGREREARALS----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELE 1589
Query: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1390
A + A + LR Q E + + + V +T++E D R E EE +
Sbjct: 1590 RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1649
Query: 1391 KKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1450
++LA++L++AE + + + + +L+ E+E+L + + K+ R
Sbjct: 1650 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1709
Query: 1451 KILAEWKQKYEESQSELES-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503
+ E ++ EE+++ E S+K + L E+ +L+ E L R +
Sbjct: 1710 AQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARR 1762
Query: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
Q++ ++ +++ + + + + ++QLE +L+ LEE +++ E + + L
Sbjct: 1763 QAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLL 1822
Query: 1564 EFNQIKAEI--ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGD 1621
+ + E+ ER + K E Q ++ + DA R+R++ +E
Sbjct: 1823 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESK 1880
Query: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
L + E QL R + K V+ + LK+ +Q+++ R D L++ + R L
Sbjct: 1881 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1940
Query: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
+ +LEE + + R+ ++EL + +E + ++ + T+L N+ ++ +
Sbjct: 1941 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQ 2000
Query: 1742 EEAVQECRNAEEKAKKA 1758
++E ++E+A++A
Sbjct: 2001 VFRLEEGVASDEEAEEA 2017
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%)
Query: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 918 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 974
Query: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
+EL VV + E ++ E+E E S ++Q +KK++ + +L+ +E
Sbjct: 975 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 1018
Query: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1078
Query: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
+K K K EA + ++E+ L E+K E K R+ + EL Q E ++
Sbjct: 1079 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1137
Query: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1138 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1197
Query: 1923 KSRDIG 1928
+ RD+G
Sbjct: 1198 QRRDLG 1203
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 611 bits (1576), Expect = e-174
Identities = 441/1431 (30%), Positives = 723/1431 (50%), Gaps = 94/1431 (6%)
Query: 37 VFVPDDKQEFVKAKIVS--REGGKVTA-----ETEYGKTVTVKEDQVMQQNPPKFDKIED 89
V++PD ++ + A+I R G KV TE +V E +NP D
Sbjct: 13 VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVN-PESLPPLRNPDILVGEND 71
Query: 90 MAMLTFLHEPAVLYNLKDRYG-SWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRS 148
+ L++LHEPAVL+NL+ R+ S +IYTYSG+ V +NPYK LP+Y ++ AY G+
Sbjct: 72 LTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMG 131
Query: 149 EAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKD 208
+ PHIF++++ AY+ M + NQSI+++GESGAGKTV+ + ++YFA ++ G +
Sbjct: 132 DMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH-- 189
Query: 209 QSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLL 268
+ED+++ +NP EA GNAKT RNDNSSRFGK+ I F ++ A++ TYLL
Sbjct: 190 -------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLL 242
Query: 269 EKSRVIFQLKAERDYHIFYQILSN-KKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327
EKSRV+FQ + ER+YHIFYQ+ ++ ++ E + L + ++Y + G T + ++D
Sbjct: 243 EKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRA 301
Query: 328 ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387
E++ T F +LGF + + ++K+ AI+H GN++ E + + L
Sbjct: 302 EMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCEL 361
Query: 388 MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447
+GL S + + LC+ ++ +E V K Q + A ALAK +Y +F+++V RIN L
Sbjct: 362 LGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL 421
Query: 448 ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 507
+ + FIGVLDI GFE FD NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 422 QFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIP 481
Query: 508 WTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPR 567
WT IDF D Q IDLIE MGI+ +L+EEC+ P TD + KL++N + ++ F+KPR
Sbjct: 482 WTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR 540
Query: 568 NIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGA 627
F + H+A V+Y G+L+KN+D + + +V + + S L + F
Sbjct: 541 ----MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTP 596
Query: 628 DAP------IEKGKGKAKKGSSF--QTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETK 679
+P ++ K K S TV + R +L LM L +T PH+VRCI PN+ K
Sbjct: 597 PSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEK 656
Query: 680 SPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSR 739
P D+ ++ QLR GVLE IRI + +P+R Y +F RY IL E F D +
Sbjct: 657 LPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MTKQELSFSDKK 714
Query: 740 KGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARM 799
+ + +L L D NQY+FG TK+FF+AG + LE++R ++L + +Q RG L R
Sbjct: 715 EVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR- 773
Query: 800 EYKKLLERRDSLLVIQWNIRAFMGV-KNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858
KK L R + L+IQ R V K + L ++ + + R
Sbjct: 774 --KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIR 831
Query: 859 LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAK 918
+ ++ +R + +L+E + LQ A + + + N IQL +
Sbjct: 832 MATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLN-IQLTYR 890
Query: 919 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978
V+ + ++LED+ + N L K L + I LE L K + E K K
Sbjct: 891 VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY 950
Query: 979 TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE----EDKVNTLTKAKVKLEQQVDDL 1034
+ ++E +AKL K L+ +Q LQ + ++K++ LTK Q DD+
Sbjct: 951 RD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTK------QLFDDV 1001
Query: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
+ Q + E + E ++ +E I L+++K QL ++ + + L A +
Sbjct: 1002 QKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEV 1061
Query: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK----LRSDLSRELEEISERL 1150
++L K++K I E E+E+E + + VEK + ++ ++ EI+++L
Sbjct: 1062 -------ARLSKQVK----TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL 1110
Query: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
E+ V+ ++ + DLE E A K A V E +
Sbjct: 1111 LESYDIEDVRSRLSVE----------DLEHLNEDGELWFAYEGLKKATRVLE-----SHF 1155
Query: 1211 QRVKQKLEK--EKSEFK-LELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQ 1267
Q K EK E FK + L ++++++ + + ++ + R ++ + +
Sbjct: 1156 QSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFK 1215
Query: 1268 RSVNDLTSQRAKLQTENGELSRQLDEK-EALISQLTRGKLTYTQQLEDLKRQLEEEVKAK 1326
+ +++L Q+ L+ E + ++ K E L +QL R + Q + L+ Q E K K
Sbjct: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
Query: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT-EE 1385
L +Q + D L++Q+E E+E K ++ S+ E + E D R ++
Sbjct: 1276 EKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEELDMKDRVIKK 1333
Query: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE---IEDLMVDVE 1433
L++ K L++ + +A + V + + L +++ ++E I++L++D++
Sbjct: 1334 LQDQVKTLSKTIGKAND-VHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
Score = 94.0 bits (232), Expect = 1e-18
Identities = 110/520 (21%), Positives = 222/520 (42%), Gaps = 63/520 (12%)
Query: 1172 QKMRRDLEE--ATLQHEATAAALRKKHADSVAELGEQID---NLQRVKQKLEKEKSEFKL 1226
++ R+ LEE A + + A L ++ S+ I +QR+++KLE + E
Sbjct: 848 RRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHG 907
Query: 1227 ELDDVTS-------NMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR-A 1278
++ +TS ++E+I K +A LEK HR EE + D ++ A
Sbjct: 908 LVEKLTSLAALRAGDVEKIQKLEAELEKAAT--------HRRNYEEKGKRYRDAVEEKLA 959
Query: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338
KLQ N EL Q ++ + + + T +++++L +QL ++V+ + L+ +
Sbjct: 960 KLQKHNSELETQKEQIQLKLQEKTE---ELKEKMDNLTKQLFDDVQKEERQRMLLEKS-- 1014
Query: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398
+L + YE++ ++ E + L ++ + E+ K++ + +
Sbjct: 1015 -FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQV-KTIS 1072
Query: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458
E E+ +E + A+ +EK + E+ + M ++ + + ++ + E
Sbjct: 1073 EFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLN 1132
Query: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE--------------HLETFKRENKN 1504
+ E E +K R L + K+ YE+ +E HL+ RE +
Sbjct: 1133 EDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREEND 1192
Query: 1505 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASL------------- 1551
+ E I +L S I + ++ +LE +K +L+ L E +
Sbjct: 1193 INESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR 1252
Query: 1552 -EHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNE 1610
+ EEG +A N+I + + KL +K +EM++A +HL+ +T + + R E
Sbjct: 1253 SQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS-DHLK--KQFETESEVKCNFRQE 1309
Query: 1611 ALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL 1650
A R+ + ++E +L +R+ + Q QVK+L +
Sbjct: 1310 ASRLTL----ENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
Score = 87.8 bits (216), Expect = 9e-17
Identities = 106/534 (19%), Positives = 235/534 (44%), Gaps = 63/534 (11%)
Query: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1368
T +++ L+++LE++ K + L L S L E+ + +AEL++
Sbjct: 888 TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
Query: 1369 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS-LEKTKHRLQNEIED 1427
A R YE + + +EE KL + E E E + K E+ K ++ N +
Sbjct: 937 ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
Query: 1428 LMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNA 1487
L DV++ L+K ++ K ++ + +++S ++E ++L E +L++
Sbjct: 997 LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
Query: 1488 YEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEA 1547
E EH+ + L+ E++ L++Q+ KTI E EK + L+A+K++++ ++
Sbjct: 1047 VEG--EHVTS-----DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
Query: 1548 EASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRS 1607
+ + + +I + LE I+ ++ +L+ +D E HL L + + +
Sbjct: 1096 KREMREKMSEITKQLLESYDIE-DVRSRLSVEDLE-------HLNEDGELWFAYEG-LKK 1146
Query: 1608 RNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN--- 1664
L + + D E EI+ N +++ LQ L ++ +++++R
Sbjct: 1147 ATRVLESHFQSQKDCYEKEIEA--LNFKVVHLSQEINHLQKLFREEN-DINESIRHEVTR 1203
Query: 1665 --------DDLKENIAIVERRNNLLQAEL----EELRAVVEQTERSRKLAEQELIETSER 1712
D K+ I+ +E++ L+ L E+++ +E+ +++E E ++R
Sbjct: 1204 LTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR 1261
Query: 1713 VQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE 1772
+ L +QN +K+K+ + ++Q + ++ E +A+ + E +
Sbjct: 1262 -KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
Query: 1773 QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL 1826
++ +R+ K ++ +K L + +A + G K+ + RE E +L
Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
Score = 71.2 bits (173), Expect = 9e-12
Identities = 97/503 (19%), Positives = 209/503 (41%), Gaps = 41/503 (8%)
Query: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENK 1503
+R + K+L E K + + +++ +S+ + ++ Y + + LE +EN
Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
Query: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
L E+++ L + I +LE ++ + + + ++E + K+ +
Sbjct: 907 GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
Query: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
E K +I+ KL EK EE+++ N + L + E R R + ++K E
Sbjct: 967 ELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKTQ 1020
Query: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD----DAVRANDDLKENIAIVERRNN 1679
+ E Q+ + + LQ L++ + D + R + +K I+ E+
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK-TISEFEKEIE 1079
Query: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQT 1739
LLQA+ ++ V+ +R + E+ + QLL S + + + ++ DL L
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITK-----QLLESYDIEDVRSRLSVE-DLEHLNE 1133
Query: 1740 EVE-----EAVQECRNAEEKAKKAITDA------AMMAEELKKEQDTSAHLERMKKNMEQ 1788
+ E E +++ E ++ D A+ + + Q+ + HL+++ +
Sbjct: 1134 DGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEIN-HLQKLFREEND 1192
Query: 1789 TIKDLQHRLDE--AEQIALKGGKKQLQKLEARVRELE---NELEAEQKRNAESV-----K 1838
+ ++H + +E + + K+Q+ +LE + ++LE NE + K E + +
Sbjct: 1193 INESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR 1252
Query: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
+ + K L Q E K +L D + ++Q K+Q E E + +
Sbjct: 1253 SQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASR 1312
Query: 1899 VQHELDEAEERADIAESQVNKLR 1921
+ E + EE D+ + + KL+
Sbjct: 1313 LTLENRDLEEELDMKDRVIKKLQ 1335
Score = 45.8 bits (107), Expect = 4e-04
Identities = 45/198 (22%), Positives = 96/198 (48%), Gaps = 21/198 (10%)
Query: 1734 LSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM---KKNMEQTI 1790
+ +LQ ++E+ +E EK AA+ A +++K Q A LE+ ++N E+
Sbjct: 891 VQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKAATHRRNYEEKG 947
Query: 1791 KDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKEL 1850
K + ++E +L KL+ ELE + E Q + E + +++ ++ L
Sbjct: 948 KRYRDAVEE-----------KLAKLQKHNSELETQKEQIQLKLQEKTEELKE---KMDNL 993
Query: 1851 TYQTEEDRKNLLRLQDLVDK-LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEER 1909
T Q +D + R + L++K +LK + Y++Q + +E+ + ++QH ++
Sbjct: 994 TKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVT 1053
Query: 1910 ADIAESQVNKLRAKSRDI 1927
+D +++V +L + + I
Sbjct: 1054 SDGLKAEVARLSKQVKTI 1071
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 601 bits (1550), Expect = e-171
Identities = 456/1502 (30%), Positives = 748/1502 (49%), Gaps = 155/1502 (10%)
Query: 37 VFVPDDKQEFVKAKIVS--REGGKVTA-ETEYGKTVTVKEDQVMQQ-----NPPKFDKIE 88
V++PD ++ + A+++ + G KV E GK + D ++ NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 89 DMAMLTFLHEPAVLYNLKDRY-GSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKR 147
D+ L++LHEPAVL+NL+ R+ S +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 148 SEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKK 207
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFA ++
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG------- 185
Query: 208 DQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
S + +E++++ +NP +E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 186 --SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
Query: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVAS-IDDA 326
LEKSRV+FQ + ER+YHIFYQ+ ++ K ML + N ++ + QG + V +DDA
Sbjct: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDA 302
Query: 327 EELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAY 386
+E+ T A +LG + + ++++ I+H GN+ F + + P E
Sbjct: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
Query: 387 LMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINAT 446
LMG++ ++ LCH ++ E K + Q A ALAK +Y ++FNW+V +N
Sbjct: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
Query: 447 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 506
L + + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
Query: 507 EWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
WT IDF D Q CI+LIE +GI+ +L+EEC PK TD T+ KL++ HL K A F+KP
Sbjct: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
Query: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFAN--- 623
R + K F + H+A V+Y G+L+KNKD + E + + + S K+L LF +
Sbjct: 542 R-LSNKA---FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
Query: 624 -------YAGADAPIEKGKGKAKKGSSFQ-------TVSALHRENLNKLMTNLRSTHPHF 669
+ P+ + K KG Q TV R +L+ LM L +T PH+
Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
Query: 670 VRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAA 729
VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F RYR+L
Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK-- 715
Query: 730 IPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQ 789
+ D ++ + +L L +D ++Y+FG TK+FF+AG + LE++R ++L RIQ
Sbjct: 716 -QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQ 774
Query: 790 AQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMG---------VKNWPWMKLYFKIKPLL 840
RG L R KK L R + + +Q +R + K ++ Y+++ +
Sbjct: 775 KTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVR 831
Query: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQE----------KNDL--- 887
+ + + + + + L+ L ++ R+ E K V + + K +
Sbjct: 832 RRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAI 889
Query: 888 --------QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK 939
++ + E L ++ K I +E K+ ++ +++++ + L K
Sbjct: 890 IYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEK 949
Query: 940 KRKLE----DECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
LE E +L+ D++ L+L+ E+E +V +L EE+A L + + + E
Sbjct: 950 LTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
Query: 996 KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1055
KK ++E A Q E V+ L + L+Q+ + L + Q+ K E ++KL
Sbjct: 1006 KKCIEE---HADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM--TETMEKKL 1060
Query: 1056 EGDLKLTQESIMDLENDKQQLDERLKKKDF--ELNALNARIEDEQALGSQLQKKLKELQA 1113
++ T++ +DL DERL+ ++ E + L R +D + + + K
Sbjct: 1061 ---VEETKQLELDLN------DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHK 1111
Query: 1114 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN-----KKRE 1168
R + E+E +++ E+E+I R EE V ++M+ +KR
Sbjct: 1112 RTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEP-SEKKVPLDMSLFLKLQKRV 1162
Query: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
E ++ ++ +++ + E + K + G +++ +Q+LE E + K EL
Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
Query: 1229 DDVTSNMEQ--IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGE 1286
+++ + + + A R L +Q+ + + + V L SQ
Sbjct: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQ---------- 1272
Query: 1287 LSRQLDEKEALISQLTRGKLT-YTQQLEDLKRQLE--EEVKAKNALAHALQSARHDCDLL 1343
+ +KEA+ + + +T T LED+++ + E +A L +S+ D L
Sbjct: 1273 ---LVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHEL 1329
Query: 1344 REQYE--EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK-------LA 1394
E E E + R+L S++ + +E +A E++ K++ LA
Sbjct: 1330 NEDGELWLVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLA 1386
Query: 1395 QRLQEAEEA-VEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 1453
Q LQ EA +EA SL+ RL NE DLM +E+ + L K+ + F K +
Sbjct: 1387 QNLQLPPEARIEA------SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
Query: 1454 AE 1455
E
Sbjct: 1441 GE 1442
Score = 73.9 bits (180), Expect = 1e-12
Identities = 134/643 (20%), Positives = 261/643 (40%), Gaps = 114/643 (17%)
Query: 1080 LKKKDFELNALNAR-IEDEQALGSQLQKKLKELQARIEE--------LEEELEAERTARA 1130
+ K++ + + AR +E + L ++ K+ +LQ +++E +E+ E +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
+ EKLRSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
Query: 1191 ALRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMC 1249
++HAD + EQ + NL+ L++EK N + +AK +M
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKEAL---------NHRIVQQAK----EMT 1053
Query: 1250 RTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYT 1309
T+E ++ EET++ DL +R + Q E SR + + L + ++T
Sbjct: 1054 ETMEKKL------VEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-----KEEMTLM 1102
Query: 1310 QQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVL----SKAN 1365
+ + + + N + S + + + + EE +E K L L K
Sbjct: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRV 1162
Query: 1366 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI 1425
+E+ Q + + + ++ E++ +K K +R Q +E + K LE +L+NE+
Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
Query: 1426 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLK 1485
N AL +K ++ A Y +L S +E E+ L+
Sbjct: 1223 ----------NELRKALSEKSA--PEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILR 1270
Query: 1486 NAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
+ E ++ +++KN + + L E + +KM+ + +
Sbjct: 1271 SQLVSQKEAIQP--KDDKNTMTDSTILLE-------------------DVQKMKDKGEIA 1309
Query: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAET 1605
+A L+ + L+++++ + E L E ++QA R L++ L ++
Sbjct: 1310 QAYIGLKETNRS---SALDYHELNEDGELWLVY--EGLKQANR-------LLESQLQSQK 1357
Query: 1606 RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAND 1665
RS NE E A R ++ K+ + Q L +QL R
Sbjct: 1358 RSHE-------------NEAE-----ALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEA 1399
Query: 1666 DLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
L+ I + N L +LE+ V + ++ K+ +++ E
Sbjct: 1400 SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Score = 55.8 bits (133), Expect = 4e-07
Identities = 100/527 (18%), Positives = 215/527 (40%), Gaps = 95/527 (18%)
Query: 1449 FDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEE 1508
+ K+ + K + Q +++ K+ + L +L L+ Y E L + + +EE
Sbjct: 918 YKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE 977
Query: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
T ++ S + E+ K+RK LE + E + E A+ + E + + E +
Sbjct: 978 AKVATGRVLSLQE---EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLL 1034
Query: 1569 KAEIE---RKLAEKDEEMEQAKRNHLRVVDSLQTSLDA-ETRSR-----NEALRVKKKME 1619
K E E ++ ++ +EM + L V ++ Q LD + R R NE R++++ +
Sbjct: 1035 KQEKEALNHRIVQQAKEMTETMEKKL-VEETKQLELDLNDERLRYQNLLNEFSRLEERYD 1093
Query: 1620 GDLNEMEIQL------------SHA-------------------NRMAAEAQKQV----- 1643
EM + + +H+ +R ++K+V
Sbjct: 1094 DLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMS 1153
Query: 1644 ------KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
K + L ++ Q+ D+ R + + + A E R + AELE ++ E
Sbjct: 1154 LFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELES 1213
Query: 1698 SRKLAEQELIETSERV----------------QLLHSQNTSLINQKKKMDADLSQLQTEV 1741
K + EL E + + ++L Q TS+ + ++ L++++
Sbjct: 1214 ENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL 1273
Query: 1742 ---EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKNMEQTIKDLQH 1795
+EA+Q + K +TD+ ++ E+++K +D + +K+ + D
Sbjct: 1274 VSQKEAIQ-----PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHE 1328
Query: 1796 RLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTE 1855
++ E + G KQ +L LE++L+++++ + + +R + +KE E
Sbjct: 1329 LNEDGELWLVYEGLKQANRL------LESQLQSQKRSHENEAEALRGEIQSLKE-----E 1377
Query: 1856 EDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
+R+ L Q+L + +++A + E N NL +++ +
Sbjct: 1378 NNRQQQLLAQNLQLPPEARIEASLQ--HEITRLTNENLDLMEQLEKQ 1422
Score = 48.9 bits (115), Expect = 5e-05
Identities = 103/510 (20%), Positives = 217/510 (42%), Gaps = 115/510 (22%)
Query: 1463 SQSELESSQKEARS----------LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
++ EL+ + EARS + ++ +L+ +E + + + NL+ +
Sbjct: 901 AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE 960
Query: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
TE+L S +LE+ LQ + EEA+ + G++L Q E +++ ++
Sbjct: 961 TEKLRS------DLER-----------LQLSEEEAKVA----TGRVLSLQEEIAKLRKDL 999
Query: 1573 ERKLAEK---DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 1629
E+ +EK +E ++ K+ ++V +L + N L+ +K+ L
Sbjct: 1000 EQTRSEKKCIEEHADRYKQETEQLVSNL--------KEENTLLKQEKE----------AL 1041
Query: 1630 SHANRMAAEAQKQVKSLQSLLKDTQIQL-----DDAVRANDDLKENIAIVERRNNLLQAE 1684
+H R+ +A++ ++++ L + QL D+ +R + L E + ER ++L
Sbjct: 1042 NH--RIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL---- 1095
Query: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
EE+ +V + K R HS N S + S E+E+
Sbjct: 1096 KEEMTLMVHVPKPGHK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI 1136
Query: 1745 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
R E KK D ++ + L++ +EQ + +Q LD E+
Sbjct: 1137 --PSRTEEPSEKKVPLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQV 1183
Query: 1805 LKGGKKQLQKLEARVRELE------NELEAEQKRNAESVKGMRK--SERRIKELTYQTEE 1856
L+ K+ ++ + R ELE ELE+E K+ + +RK SE+ E+T
Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP 1243
Query: 1857 DRKNLL-RLQDLVDKLQLKVK---------AYKRQAEEAEEQANTNLSKFRKVQHELDEA 1906
+ L+ +L + ++L ++ + +++A + ++ NT ++ + ++ +
Sbjct: 1244 AYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKM 1302
Query: 1907 EERADIAESQVN-KLRAKSRDIGTKGLNEE 1935
+++ +IA++ + K +S + LNE+
Sbjct: 1303 KDKGEIAQAYIGLKETNRSSALDYHELNED 1332
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 600 bits (1548), Expect = e-171
Identities = 452/1491 (30%), Positives = 741/1491 (49%), Gaps = 160/1491 (10%)
Query: 37 VFVPDDKQEFVKAKIVS--REGGKVTA-ETEYGKTVTVKEDQVMQQ-----NPPKFDKIE 88
V++PD ++ + A+++ + G KV E GK + D ++ NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 89 DMAMLTFLHEPAVLYNLKDRY-GSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKR 147
D+ L++LHEPAVL+NL+ R+ S +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 148 SEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKK 207
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFA ++
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG------- 185
Query: 208 DQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
S + +E++++ +NP +E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 186 --SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
Query: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVAS-IDDA 326
LEKSRV+FQ + ER+YHIFYQ+ ++ K ML + N ++ + QG + V +DDA
Sbjct: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDA 302
Query: 327 EELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAY 386
+E+ T A +LG + + ++++ I+H GN+ F + + P E
Sbjct: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
Query: 387 LMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINAT 446
LMG++ ++ LCH ++ E K + Q A ALAK +Y ++FNW+V +N
Sbjct: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
Query: 447 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 506
L + + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
Query: 507 EWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
WT IDF D Q CI+LIE +GI+ +L+EEC PK TD T+ KL++ HL K A F+KP
Sbjct: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
Query: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFAN--- 623
R + K F + H+A V+Y G+L+KNKD + E + + + S K+L LF +
Sbjct: 542 R-LSNKA---FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
Query: 624 -------YAGADAPIEKGKGKAKKGSSFQ-------TVSALHRENLNKLMTNLRSTHPHF 669
+ P+ + K KG Q TV R +L+ LM L +T PH+
Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
Query: 670 VRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAA 729
VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F RYR+L
Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK-- 715
Query: 730 IPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQ 789
+ D ++ + +L L +D ++Y+FG TK+FF+AG + LE++R ++L RIQ
Sbjct: 716 -QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQ 774
Query: 790 AQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMG---------VKNWPWMKLYFKIKPLL 840
RG L R KK L R + + +Q +R + K ++ Y+++ +
Sbjct: 775 KTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVR 831
Query: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQE----------KNDL--- 887
+ + + + + + L+ L ++ R+ E K V + + K +
Sbjct: 832 RRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAI 889
Query: 888 --------QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK 939
++ + E L ++ K I +E K+ ++ +++++ + L K
Sbjct: 890 IYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEK 949
Query: 940 KRKLE----DECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
LE E +L+ D++ L+L+ E+E +V +L EE+A L + + + E
Sbjct: 950 LTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
Query: 996 KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1055
KK ++E A Q E V+ L + L+Q+ + L + Q+ K E ++KL
Sbjct: 1006 KKCIEE---HADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM--TETMEKKL 1060
Query: 1056 EGDLKLTQESIMDLENDKQQLDERLKKKDF--ELNALNARIEDEQALGSQLQKKLKELQA 1113
++ T++ +DL DERL+ ++ E + L R +D + + + K
Sbjct: 1061 ---VEETKQLELDLN------DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHK 1111
Query: 1114 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN-----KKRE 1168
R + E+E +++ E+E+I R EE V ++M+ +KR
Sbjct: 1112 RTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEP-SEKKVPLDMSLFLKLQKRV 1162
Query: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
E ++ ++ +++ + E + K + G +++ +Q+LE E + K EL
Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
Query: 1229 DDVTSNMEQ--IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGE 1286
+++ + + + A R L +Q+ + + + V L SQ
Sbjct: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQ---------- 1272
Query: 1287 LSRQLDEKEALISQLTRGKLT-YTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLRE 1345
+ +KEA+ + + +T T LED+ +++K K +A A + LL
Sbjct: 1273 ---LVSQKEAIQPKDDKNTMTDSTILLEDV-----QKMKDKGEIAQAYIGLKETNRLLES 1324
Query: 1346 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEA-V 1404
Q + + K + E + E +++ EE ++ LAQ LQ EA +
Sbjct: 1325 QLQSQ------------KRSHENEAEALRGEIQSLK--EENNRQQQLLAQNLQLPPEARI 1370
Query: 1405 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
EA SL+ RL NE DLM +E+ + L K+ + F K + E
Sbjct: 1371 EA------SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415
Score = 73.2 bits (178), Expect = 2e-12
Identities = 165/709 (23%), Positives = 279/709 (39%), Gaps = 157/709 (22%)
Query: 1080 LKKKDFELNALNAR-IEDEQALGSQLQKKLKELQARIEE--------LEEELEAERTARA 1130
+ K++ + + AR +E + L ++ K+ +LQ +++E +E+ E +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
+ EKLRSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
Query: 1191 ALRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMC 1249
++HAD + EQ + NL+ L++EK N + +AK +M
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKEAL---------NHRIVQQAK----EMT 1053
Query: 1250 RTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLT------- 1302
T+E ++ EET++ DL +R + Q E SR + + L ++T
Sbjct: 1054 ETMEKKL------VEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPK 1107
Query: 1303 ----RGKLTYTQ------------QLEDLKRQLEEEVKAKNALAHAL----QSARHDCDL 1342
R T++ ++ED+ + EE + K L +L Q + +
Sbjct: 1108 PGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQ 1167
Query: 1343 LREQYEEETEAKAELQRVLSKANSEVA-QWR-TKYETDAIQRTEELEEAKKKLAQRLQEA 1400
++ ++E + K E Q + SKA E Q R + E ++++R +ELE KKL L E
Sbjct: 1168 EKQVMQDELDRKEE-QVLRSKAKEEERPQIRGAELEYESLKR-QELESENKKLKNELNEL 1225
Query: 1401 EEAVEAVNAK-------------CSSLEKTKHRLQNEIEDLMVD----VERSNAAAAALD 1443
+A+ +A L L E++++ V + A D
Sbjct: 1226 RKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDD 1285
Query: 1444 KKQRNFDKILAEWKQKYEES---------------------QSELESSQKEARSLSTELF 1482
K IL E QK ++ QS+ S + EA +L E+
Sbjct: 1286 KNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQ 1345
Query: 1483 KLK---NAYEESLEH---LETFKRENKNLQEEIS-------DLTEQLGSSGKTIHELEKV 1529
LK N ++ L L R +LQ EI+ DL EQL KT+ +L+K
Sbjct: 1346 SLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQ 1405
Query: 1530 RK-------QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFN---QIKAEIERKLAEK 1579
K +LE +ME S + + + I R + +F + K E E+KL K
Sbjct: 1406 LKVFAKKIGELEVGQMENISPGQIIDEPI--RPVNIPRKEKDFQGMLEYKKEDEQKLV-K 1462
Query: 1580 DEEMEQAKR-------------------NHLRVVDSLQTSLDAETRSRNEALRVKKKMEG 1620
+ +E R H ++ Q T + N +V KK
Sbjct: 1463 NLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGD 1522
Query: 1621 DLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE 1669
D + LS+ R KQ + +K + ++ N DL E
Sbjct: 1523 DFETVSFWLSNTCRF-LHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAE 1570
Score = 67.4 bits (163), Expect = 1e-10
Identities = 113/539 (20%), Positives = 222/539 (41%), Gaps = 73/539 (13%)
Query: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
++E + K+E V + I + + ++ R +++Q +++ E+ S+
Sbjct: 902 KRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSET 961
Query: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA-HALQSA 1336
KL+++ L QL E+EA ++ T L+ +++ L++ LE+ K + HA
Sbjct: 962 EKLRSDLERL--QLSEEEAKVA--TGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHA---- 1013
Query: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA-KKKLAQ 1395
++Y++ETE +L L + N+ + Q + +Q+ +E+ E +KKL +
Sbjct: 1014 --------DRYKQETE---QLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVE 1062
Query: 1396 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDL------MVDVERSNAAAAALDKKQRNF 1449
++ E + + +L RL+ +DL MV V +
Sbjct: 1063 ETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNES 1122
Query: 1450 DKILAEWKQKYEE--SQSELESSQKEARSLS---------TELFKLKNAYEESLEHLETF 1498
+ I + + E+ S++E S +K +S TEL + K ++ L+ E
Sbjct: 1123 EYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQ 1182
Query: 1499 KRENKNLQEEISDLT-EQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG- 1556
+K +EE + +L ELE K+L+ E EL+ AL E A G
Sbjct: 1183 VLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGA 1242
Query: 1557 ---KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALR 1613
++L QL + +L + EE+ + + +++Q D T + + L
Sbjct: 1243 PAYRVLMEQL------TSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILL 1296
Query: 1614 V---KKKMEGDLNEMEIQLSHANRMA-AEAQKQVKS-----------LQSLLKDTQ---- 1654
K K +G++ + I L NR+ ++ Q Q +S +QSL ++
Sbjct: 1297 EDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQ 1356
Query: 1655 -----IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
+QL R L+ I + N L +LE+ V + ++ K+ +++ E
Sbjct: 1357 LLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415
Score = 56.6 bits (135), Expect = 2e-07
Identities = 89/495 (17%), Positives = 200/495 (40%), Gaps = 58/495 (11%)
Query: 1449 FDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEE 1508
+ K+ + K + Q +++ K+ + L +L L+ Y E L + + +EE
Sbjct: 918 YKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE 977
Query: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
T ++ S + E+ K+RK LE + E + E A+ + E + + E +
Sbjct: 978 AKVATGRVLSLQE---EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLL 1034
Query: 1569 KAEIE---RKLAEKDEEM-EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNE 1624
K E E ++ ++ +EM E ++ + L+ L+ E L ++E ++
Sbjct: 1035 KQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDD 1094
Query: 1625 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAND------------------- 1665
++ +++ + K+ S S + I + D
Sbjct: 1095 LKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSL 1154
Query: 1666 --DLKENIAIVERRNNLLQAELEE-----LRAVVEQTERSRKLAEQELIETSERVQLLHS 1718
L++ + +E+ ++Q EL+ LR+ ++ ER ++ EL S + Q L S
Sbjct: 1155 FLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP-QIRGAELEYESLKRQELES 1213
Query: 1719 QNTSLINQKKKMDADLSQLQTEVEEA---------VQECRNAEEKAKKAITDAAMMAEEL 1769
+N L N+ ++ LS+ A +++ + E+ + ++ +L
Sbjct: 1214 ENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL 1273
Query: 1770 KKEQDTSAHLERMKKNMEQTI--KDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
+++ + + TI +D+Q D+ E G K+ +L LE++L+
Sbjct: 1274 VSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRL------LESQLQ 1327
Query: 1828 AEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
++++ + + +R + +KE E +R+ L Q+L + +++A + E
Sbjct: 1328 SQKRSHENEAEALRGEIQSLKE-----ENNRQQQLLAQNLQLPPEARIEASLQ--HEITR 1380
Query: 1888 QANTNLSKFRKVQHE 1902
N NL +++ +
Sbjct: 1381 LTNENLDLMEQLEKQ 1395
Score = 50.4 bits (119), Expect = 2e-05
Identities = 105/509 (20%), Positives = 218/509 (42%), Gaps = 105/509 (20%)
Query: 1463 SQSELESSQKEARS----------LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
++ EL+ + EARS + ++ +L+ +E + + + NL+ +
Sbjct: 901 AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE 960
Query: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
TE+L S +LE+ LQ + EEA+ + G++L Q E +++ ++
Sbjct: 961 TEKLRS------DLER-----------LQLSEEEAKVA----TGRVLSLQEEIAKLRKDL 999
Query: 1573 ERKLAEK---DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 1629
E+ +EK +E ++ K+ ++V +L + N L+ +K+ L
Sbjct: 1000 EQTRSEKKCIEEHADRYKQETEQLVSNL--------KEENTLLKQEKE----------AL 1041
Query: 1630 SHANRMAAEAQKQVKSLQSLLKDTQIQL-----DDAVRANDDLKENIAIVERRNNLLQAE 1684
+H R+ +A++ ++++ L + QL D+ +R + L E + ER ++L
Sbjct: 1042 NH--RIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL---- 1095
Query: 1685 LEELRAVV-------EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLS-- 1735
EE+ +V ++T+ + E E I +SE ++ + + +KK+ D+S
Sbjct: 1096 KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLF 1155
Query: 1736 -QLQTEVEEAVQECR----------------NAEEKAKKAITDAAMMAEELKKEQDTSAH 1778
+LQ V E QE + A+E+ + I A + E LK+++
Sbjct: 1156 LKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQE----- 1210
Query: 1779 LERMKKNMEQTIKDLQHRLDE--AEQIALKGGKKQLQKLEARVRELENELEAEQKRNAES 1836
LE K ++ + +L+ L E A ++ G +E ++ + EL+ + E
Sbjct: 1211 LESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLME-QLTSVSEELDVRK----EE 1265
Query: 1837 VKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQ-LKVKAYKRQAEEAEEQANTNLSK 1895
V +R KE Q ++D+ + L++ +Q +K K QA ++ N L
Sbjct: 1266 VLILRSQLVSQKE-AIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLES 1324
Query: 1896 FRKVQHELDEAEERADIAESQVNKLRAKS 1924
++Q + E A+ ++ L+ ++
Sbjct: 1325 --QLQSQKRSHENEAEALRGEIQSLKEEN 1351
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 578 bits (1491), Expect = e-164
Identities = 444/1511 (29%), Positives = 748/1511 (49%), Gaps = 188/1511 (12%)
Query: 37 VFVPDDKQEFVKAKIVS--REGGK-----VTAETEYGKTVTVKEDQV-MQQNPPKFDKIE 88
V++PD + + A++ +EG K + ET + V+ +Q+ +NP
Sbjct: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
Query: 89 DMAMLTFLHEPAVLYNLKDRY-GSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKR 147
D+ L++LHEPAVL+NLK R+ S IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
Query: 148 SEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKK 207
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFA +
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG------- 185
Query: 208 DQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
S + +E++++ ++P +EA GNAKT RNDNSSRFGK+I+I F + A++ TYL
Sbjct: 186 --SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYL 243
Query: 268 LEKSRVIFQLKAERDYHIFYQILSNKK-PELLDMLLITNNPYDYAFISQG-ETTVASIDD 325
LEKSRV+FQ ER+YHIFYQ+ + PE ++ L + D+ + SQG +T++ +DD
Sbjct: 244 LEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEGVDD 301
Query: 326 AEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTE--EADK 383
AE+ T AF +LG + S++K+ +I+H G++ QAE DG + +
Sbjct: 302 AEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCSISPQ 354
Query: 384 SAYL------MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFN 437
YL +G+ + + LCH ++ +E K ++QQVI A ALAK +Y ++F
Sbjct: 355 DVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFG 414
Query: 438 WMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLE 497
W+V IN L T + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LE
Sbjct: 415 WIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474
Query: 498 QEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHL 557
QEEY KE I WT IDF D Q CIDLIE +GI+ +L+EEC PK TD + KL+D H
Sbjct: 475 QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH- 532
Query: 558 GKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLL 617
S +FQKPR F ++H+A V+Y G+L+KN+D + E + + + S L+
Sbjct: 533 SSSQHFQKPR----MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588
Query: 618 STLFANYAGADAPIEKGKGKAKKGS--------------SFQTVSALHRENLNKLMTNLR 663
+ LF + GKG + K S +TV R +L+ LM L
Sbjct: 589 ADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLN 648
Query: 664 STHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYR 723
+T PH+VRCI PN+ K P D + QLR GVLE IRI G+P+R Y DF RYR
Sbjct: 649 ATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYR 708
Query: 724 ILNPAAIPEGQFIDSRKGA--EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL 781
+L + + + ++ K A +L +L D ++++FG TK+FF+AG + LE++R ++
Sbjct: 709 VL----VKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKF 764
Query: 782 SRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMG---------VKNWPWMKL 832
IQ RG L +++Y +L + + L +Q R + ++ ++
Sbjct: 765 RTATIMIQKTVRGWLQKVKYHRL---KGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQK 821
Query: 833 YFKIKPLLKSAEREKEMASMKEEFTR-------------------LKEALEKSEARRKEL 873
+++++ ++ +R + A + + FTR +++ + ARR
Sbjct: 822 HYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQ 881
Query: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
+ +++ + L+ + E L + L + + +E KV ++ ++ +E N
Sbjct: 882 RLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKI---DEQN 938
Query: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
E +L S +++ L+ L V ++ E+ L EE+ L + +
Sbjct: 939 KEFKTLSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQRAH 996
Query: 994 KEKKALQEAHQQALDDLQ---AEEDKVNTLTK-AKVKLEQQV-----DDLEGSLEQEKKV 1044
E+K L++AH + D+L+ A+ ++ N L K K +L Q+ D+ + +E +
Sbjct: 997 SERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLM 1056
Query: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN-ARIEDEQALGSQ 1103
+ +LE + + + +K + +N + ++ + N N + +E + S
Sbjct: 1057 KKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSI 1116
Query: 1104 LQKKLKELQARIEELEE---------------------ELEAERTARAKVEKLRSDLSRE 1142
++ + + ++++EE ELE ER +KL+ L +
Sbjct: 1117 STSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQER------KKLQVQLEKR 1170
Query: 1143 LEEISERLEEAGGATSVQIEMN----------KKREAEFQKMRRDLEE--ATLQHEATAA 1190
++ S++++ T + ++ N ++ E+E +K++ DL E + +AT
Sbjct: 1171 EQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQN 1230
Query: 1191 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII---KAKANLEK 1247
DS + L ++ L+ ++LE K E + + S ++ + A+ N+
Sbjct: 1231 NSSHGSPDSYSLL---LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINA 1287
Query: 1248 MCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK--LQTENGELS---RQLDEKEALI-SQL 1301
+ + + A E V S+ E+GEL + L + L+ +QL
Sbjct: 1288 RSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQL 1347
Query: 1302 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
L + +++E LK QL EE K + L LL + + E + E+
Sbjct: 1348 QAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTL--------LLSPEAQVEFGVQQEI 1399
Query: 1358 QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ---EAEEAVEAVNAKCSSL 1414
R+ T D + E+LE+ ++KL ++L+ + + +EA A S
Sbjct: 1400 SRL------------TNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQS- 1446
Query: 1415 EKTKHRLQNEI 1425
E+ +H L ++
Sbjct: 1447 ERKRHELNRQV 1457
Score = 73.2 bits (178), Expect = 2e-12
Identities = 131/645 (20%), Positives = 254/645 (39%), Gaps = 118/645 (18%)
Query: 1291 LDEKEALISQLTRGKLT--YTQQLEDLKRQLE---EEVKAKNALAHALQSARHDCDLLRE 1345
++ K I + RG + + Q+L D ++ +KA+ L AR L R
Sbjct: 860 MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRL 919
Query: 1346 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVE 1405
E + +LQR + + N E + T E+E KK+L Q
Sbjct: 920 NVGMENKV-VQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQ------- 971
Query: 1406 AVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL----------------------- 1442
S E T RLQ E+E L +++R+++ L
Sbjct: 972 ------SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENA 1025
Query: 1443 ---DKKQRNFDKILAEWKQKYEES-------QSELESSQKEARSLSTELFKLKNAYEESL 1492
D+K++ ++IL + K ++ ++ + ELE + ++L E +L+ Y+
Sbjct: 1026 LLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLR 1085
Query: 1493 EHLETFK-----RENKNLQEEI-------SDLTEQLGSSGKTIHELEKVRKQLEAEKMEL 1540
+ + K R N + Q + S T ++G + + ++E++ + A M +
Sbjct: 1086 DEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTV 1145
Query: 1541 QSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS 1600
L++ LE E K L+ QLE K ++D + QA+ +
Sbjct: 1146 FLKLQKRVRELEQERKK-LQVQLE----------KREQQDSKKVQAEPPQTDIDLDPNAD 1194
Query: 1601 LDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1660
L + R E KK++ DLNE+ + A+ Q S + L+
Sbjct: 1195 LAYNSLKRQELESENKKLKNDLNEL-------RKAVADQATQNNSSHGSPDSYSLLLNQL 1247
Query: 1661 VRANDDL---KENIAIVERRNNLLQAELEEL---RAVVEQTERSRKLAEQELIETSERVQ 1714
A+++L KE + I+ R ++ A+ L A RS ++ ++ + ++
Sbjct: 1248 KLAHEELEVRKEEVLIL--RTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIE 1305
Query: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQD 1774
H + Q D L + E + + ++ A+ + +A + A+ L+ E++
Sbjct: 1306 AYHG-----VCQTNSKTEDWGYLNEDGELGL-AYQGLKQVAR--LLEAQLQAQSLEHEEE 1357
Query: 1775 T---SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG---------------KKQLQKLE 1816
A LE +K+ M++ + L + + ++ G K+ ++KLE
Sbjct: 1358 VEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLE 1417
Query: 1817 ARVRELENELEAEQKR--NAESVKGMRKSERRIKELTYQTEEDRK 1859
R+L+ +L+ K+ + E+ + + +SER+ EL Q RK
Sbjct: 1418 KNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 518 bits (1334), Expect = e-146
Identities = 433/1707 (25%), Positives = 813/1707 (47%), Gaps = 235/1707 (13%)
Query: 47 VKAKIVSREGGKVTAETEY-GKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNL 105
+K++ ++ GKV + ++ G + V ED V + N P D++ED+A L +L+E +VL+ L
Sbjct: 366 LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
Query: 106 KDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165
+ RYG+ +++TY+G + + P VY+ +V+ ++G +R + PHI++++ AY+ M
Sbjct: 426 RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
Query: 166 LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANP 225
L R++QSI++ G SG+GKT + + ++QY A IA I S K ++
Sbjct: 486 LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--------SGNKVFSVEKWQALYT 537
Query: 226 ALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHI 285
LEAFGN+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E +++
Sbjct: 538 LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNV 597
Query: 286 FYQILS----NKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGF 341
FY +L+ + EL L NN + +++ E + +L A A VLG
Sbjct: 598 FYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGI 654
Query: 342 TSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEE-ADKSAYLMGLNSADLLKGLC 400
+ +E+ + + + AI H G + E + E A K+AYL+G + +L +
Sbjct: 655 SPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIF 714
Query: 401 HPRVKVG----NEYVTKGQNVQQVIYATG----------ALAKAVYERMFNWMVTRINAT 446
+ K G + +G + TG +A +Y +F +V+ +N
Sbjct: 715 KHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRA 774
Query: 447 LETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLEQEE 500
L++ Q + ++D GF+ + SFE+LC N+T ++LQ+ F+ FV E E
Sbjct: 775 LKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELER 834
Query: 501 YKKEGIEWTFIDFGM---DLQACID------------LIEKPMGIMSILEEECMFPKATD 545
YK+E IE F D D A +D ++ G++ +LEEE + P A++
Sbjct: 835 YKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASE 894
Query: 546 MTFKAKLFDNHLGKSAN--FQKPRNIKGKPEAHFSLIHYAGI--VDYNIIGWLQKNK-DP 600
T +LF + + + Q P KP HF L H G V+YN+ GWL K +P
Sbjct: 895 DTLLERLFSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNP 953
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGS------------SFQT-V 647
+ L Q S K++S LF AG+ + + GS +F T +
Sbjct: 954 ATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGM 1013
Query: 648 SALHRENL--------NKLMTNLRSTHPHFVRCIIP------NETKSPG----------- 682
+A+ +++L + L+ ++ + HFV C +P E +S
Sbjct: 1014 AAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELD 1073
Query: 683 ------------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730
+D PL+ QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L P
Sbjct: 1074 LPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLT 1133
Query: 731 PEGQ----FIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 786
+ +D R+ E+LL LD++ + G ++VFF+AG L LEE RDE+ SR +T
Sbjct: 1134 KKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLT 1193
Query: 787 RIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAERE 846
QA RG LAR +KK + ++ +Q NI+ GVK+WPW KL+ ++PL++ E
Sbjct: 1194 LFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSE 1253
Query: 847 KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906
+++ + EE +L+ LEK+E R EL L ++L ++ E++ A + D
Sbjct: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLD 1313
Query: 907 QLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKRDIDD------L 957
+++ E ++KE+ + L+ + E+ E+ + +L +E+ ++DD
Sbjct: 1314 AETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDAGGEW 1371
Query: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK- 1016
L + +E T+ +++ E+ +++ + K+ L ++ L DLQA+ ++
Sbjct: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQADSEES 1421
Query: 1017 ---VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK 1073
+ L K +L ++ D + LE ++ +LE+ +R+ + +L E + + +K
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREK 1478
Query: 1074 QQLDERLKKKDF---ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Q ++ ++KD E +L ++E++ + +K+ L+A ++++ + + + A
Sbjct: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Query: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
KV+K DL ++++ E L+E G + LE+A L+ E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEME 1580
Query: 1191 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
+R+ H+ + E++ + +Q +K+ + +++L++ + +++++ K LE
Sbjct: 1581 RMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
Query: 1251 TLEDQMNEHRSKAEETQRS--------------VNDLTSQRAKLQTENGELSRQLDEKEA 1296
TL DQ+N ++E+ R + D A + E +L QL+E E
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
Query: 1297 LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1356
+ + + ++EDL Q+++ KAK AL L + + + ++ + EE+ E +
Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE---D 1754
Query: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
+ ++ K + VAQ A + LAQ + + + +E N + L++
Sbjct: 1755 MNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQE 1795
Query: 1417 TKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1476
LQ+++E L E+S + + +++ + E + + E +++++ + A
Sbjct: 1796 KLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLESLASR 1847
Query: 1477 LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA- 1535
L + KL ++ + K +NK LQ ++ D E++G E RK+ EA
Sbjct: 1848 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMG---------ELARKEAEAS 1898
Query: 1536 -EKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVV 1594
+K EL+ LE EA+ + + + A ++A IE +EME + L +
Sbjct: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE-------DEMESDENEDL--I 1949
Query: 1595 DSLQTSLDAETRSRNEALRVKKKMEGD 1621
+SLQ D T+ + K K+EGD
Sbjct: 1950 NSLQ---DMVTKYQKR----KNKLEGD 1969
Score = 193 bits (490), Expect = 2e-48
Identities = 178/797 (22%), Positives = 373/797 (46%), Gaps = 39/797 (4%)
Query: 1138 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1192
D R +EE+ E LE++ G + V E Q+ + TL A L
Sbjct: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
Query: 1193 RKKHADSVAELGEQIDNL--QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
++H +I +L + V++ ++K K + + + +I+ + + E+ R
Sbjct: 1204 ARQHFKK-----RKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIR 1257
Query: 1251 TLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL-DEKEA------LISQLTR 1303
++++ + RSK E+ ++ N+L +L++ EL+ +L DE+ L+ T
Sbjct: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
Query: 1304 GKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1363
+L +++++L+ Q + K + + AR ++ +A E + +
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
Query: 1364 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423
A EV + + + + + E ++ K++L +RL + + E L+K RL
Sbjct: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
Query: 1424 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1483
E++D + +E L+KKQR FD L++ ++ + + + E Q+E L E F
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
LK EE + F ++ +L+ E+ D++ Q ++ +++K + LEA+ + +
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
Query: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
L+E +++ E LR ++E +++ +++ +DEE+E+A+++ + + ++ L+
Sbjct: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
E + + LR K+++EG L + Q+ NR E++K+ L+ LK T+ L DA
Sbjct: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
Query: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
D LK N A +R L+ +LEE ++RK E E+ + ++ + T+L
Sbjct: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
Query: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1780
Q ++ + +++Q +EE ++ +K K A+ A + +L + D A LE
Sbjct: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
Query: 1781 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGM 1840
+ K+ +++ ++ LQ +++ EQ + K + + EA++RELE LE E+ + VK +
Sbjct: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
Query: 1841 RKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1900
R+KE + E+R + ++ + +++ R +E + ++ + +
Sbjct: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
Query: 1901 HELDEAEERADIAESQV 1917
HEL+ E + A +
Sbjct: 1902 HELEMDLESLEAANQSL 1918
Score = 170 bits (431), Expect = 1e-41
Identities = 203/875 (23%), Positives = 395/875 (45%), Gaps = 98/875 (11%)
Query: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH----QQALDDLQAEED 1015
TLA++E+++ E +NLT A +A+ +K+ +Q+ Q+ + + +D
Sbjct: 1176 TLARLEEQRD--EQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233
Query: 1016 ----KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN 1071
K+ T + ++++ + + E+ +++R LE+A+++ +L+L + LE+
Sbjct: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKE-RNELRLNSDR---LES 1289
Query: 1072 DKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
+L L + + + ++ E A + +K++KELQ + + L++++E +
Sbjct: 1290 RISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
Query: 1132 VEKLRS-DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR--RDLEEATLQHEAT 1188
+R+ +++ E+++ ++AGG ++ E RE +F K R ++ E+ +
Sbjct: 1350 ARLIRAAEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEVEQQN 1403
Query: 1189 AAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM 1248
L ++ D A+ E QR Q+L+K+ EL D ++E LEK
Sbjct: 1404 KRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
Query: 1249 CRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTY 1308
R + ++++ +A+ + L ++ L E L +QL+EK+ I+ T+ ++
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
Query: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN--- 1365
+L+D+ Q E K + +LA + R D + + EEE + +A ++L +A
Sbjct: 1520 EAELQDISSQ---ESKDEASLAKVKKQLR-DLEAKVKDQEEELDEQAGTIQMLEQAKLRL 1575
Query: 1366 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424
E+ + R + + R EE+EEA++ ++L++ E +E + + K L+ +
Sbjct: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
Query: 1425 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 1484
+ L V R + + ++ K L K ++Q L+ + A S E+ +L
Sbjct: 1636 LATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-KREIAQL 1688
Query: 1485 KNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSAL 1544
KN EES + K ++ EI DL Q+ K LE+ +L+ EK E+Q+ L
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
Query: 1545 EE----------------AEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAK 1587
EE A+AS + + L+AQLE N+ K E++ KL ++E +
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1808
Query: 1588 RNHL---------RVVDSLQTSLDAET----RSRNEALRVKKKMEGDLNEMEIQLSHANR 1634
++ + + L+T L+ E R + A R+K+ ME E + +++ NR
Sbjct: 1809 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENR 1868
Query: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
++Q K LQ L+DT+ ++ + R A R+ + L+ +LE L A +
Sbjct: 1869 ----EKEQNKRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLESLEAANQS 1917
Query: 1695 TERSRKLA-------------EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
+ KLA E E E + + L T +K K++ D S + +E+
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGD-SDVDSEL 1976
Query: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS 1776
E+ V ++ K K + AA LK TS
Sbjct: 1977 EDRVDGVKSWLSK-NKGPSKAASDDGSLKSSSPTS 2010
Score = 118 bits (296), Expect = 5e-26
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 68/594 (11%)
Query: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT---KYETDAIQRTEELEEAKK--KL 1393
+ L EQ + E +L+ L KA E + R + E+ + T EL + + +
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 1394 AQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452
A +L +AE A + L+ L+ ++E + ++V + AA + + D
Sbjct: 1308 ASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDA 1367
Query: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
EW+ KYE + E++ ++K +L+ +E+ LE + KR+ L+ + DL
Sbjct: 1368 GGEWRLKYERAVREVDFTKK----------RLQQEFEDKLEVEQQNKRQ---LERRLGDL 1414
Query: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
S + + +L+K ++L AE + + LE + E K R E +Q E
Sbjct: 1415 QADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA 1474
Query: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
+R+ ++ E++++ K L SL+ L+ + + +E +L ++ Q S
Sbjct: 1475 QREKLQR-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKD 1533
Query: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
A+ +KQ++ L++ +KD + +LD+ I ++E+ L+ E+E +R
Sbjct: 1534 EASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTH 1586
Query: 1693 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
+ SR ++E+ E + Q + K+M+ L + + ++ ++E R E
Sbjct: 1587 SKEMESR---DEEVEEARQSCQ----------KKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 1753 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGK 1809
K A +++++ + S +R++K++++T + D Q LD + A
Sbjct: 1634 GKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS--- 1681
Query: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
+ + +L+N+LE + A +VK + E I++L Q ++ K L++ +
Sbjct: 1682 ------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
Query: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923
+LQ + + + EE +E N + K H+ A+ D+A Q+N L+A+
Sbjct: 1736 RLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQ 1782
Score = 80.1 bits (196), Expect = 2e-14
Identities = 68/319 (21%), Positives = 154/319 (48%), Gaps = 18/319 (5%)
Query: 1625 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
+E+QLS ++Q+++ ++ + +L+ A + ++L+ N +E R + L +E
Sbjct: 1247 IEVQLS---------EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSE 1297
Query: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ----TE 1740
L + R E + E + + ++ L +Q +L Q + M+ ++ + + E
Sbjct: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
Query: 1741 VEEAVQECRNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTIKDLQHR 1796
+ V + E K ++A+ + + L++E + +E+ K+ +E+ + DLQ
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
Query: 1797 LDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1856
+E+++ AL+ KK+ Q+L A +++ + LE +Q RN E K R+ + + + + +
Sbjct: 1418 SEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
Query: 1857 DRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1916
++ +LQ D L + + K+Q EE + K ++ EL + + E+
Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
Query: 1917 VNKLRAKSRDIGTKGLNEE 1935
+ K++ + RD+ K ++E
Sbjct: 1537 LAKVKKQLRDLEAKVKDQE 1555
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 515 bits (1326), Expect = e-145
Identities = 420/1668 (25%), Positives = 796/1668 (47%), Gaps = 219/1668 (13%)
Query: 47 VKAKIVSREGGKVTAETEY-GKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNL 105
+K++ ++ GKV + ++ G + V ED V + N P D++ED+A L +L+E +VL+ L
Sbjct: 366 LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
Query: 106 KDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165
+ RYG+ +++TY+G + + P VY+ +V+ ++G +R + PHI++++ AY+ M
Sbjct: 426 RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
Query: 166 LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANP 225
L R++QSI++ G SG+GKT + + ++QY A IA I S K ++
Sbjct: 486 LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--------SGNKVFSVEKWQALYT 537
Query: 226 ALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHI 285
LEAFGN+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E +++
Sbjct: 538 LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNV 597
Query: 286 FYQILS----NKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGF 341
FY +L+ + EL L NN + +++ E + +L A A VLG
Sbjct: 598 FYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGI 654
Query: 342 TSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEE-ADKSAYLMGLNSADLLKGLC 400
+ +E+ + + + AI H G + E + E A K+AYL+G + +L +
Sbjct: 655 SPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIF 714
Query: 401 HPRVKVG----NEYVTKGQNVQQVIYATG----------ALAKAVYERMFNWMVTRINAT 446
+ K G + +G + TG +A +Y +F +V+ +N
Sbjct: 715 KHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRA 774
Query: 447 LETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLEQEE 500
L++ Q + ++D GF+ + SFE+LC N+T ++LQ+ F+ FV E E
Sbjct: 775 LKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELER 834
Query: 501 YKKEGIEWTFIDFGM---DLQACID------------LIEKPMGIMSILEEECMFPKATD 545
YK+E IE F D D A +D ++ G++ +LEEE + P A++
Sbjct: 835 YKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASE 894
Query: 546 MTFKAKLFDNHLGKSAN--FQKPRNIKGKPEAHFSLIHYAGI--VDYNIIGWLQKNK-DP 600
T +LF + + + Q P KP HF L H G V+YN+ GWL K +P
Sbjct: 895 DTLLERLFSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNP 953
Query: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGS------------SFQT-V 647
+ L Q S K++S LF AG+ + + GS +F T +
Sbjct: 954 ATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGM 1013
Query: 648 SALHRENL--------NKLMTNLRSTHPHFVRCIIP------NETKSPG----------- 682
+A+ +++L + L+ ++ + HFV C +P E +S
Sbjct: 1014 AAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELD 1073
Query: 683 ------------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730
+D PL+ QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L P
Sbjct: 1074 LPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLT 1133
Query: 731 PEGQ----FIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 786
+ +D R+ E+LL LD++ + G ++VFF+AG L LEE RDE+ SR +T
Sbjct: 1134 KKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLT 1193
Query: 787 RIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAERE 846
QA RG LAR +KK + ++ +Q NI+ GVK+WPW KL+ ++PL++ E
Sbjct: 1194 LFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSE 1253
Query: 847 KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906
+++ + EE +L+ LEK+E R EL L ++L ++ E++ A + D
Sbjct: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLD 1313
Query: 907 QLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKRDIDD------L 957
+++ E ++KE+ + L+ + E+ E+ + +L +E+ ++DD
Sbjct: 1314 AETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDAGGEW 1371
Query: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK- 1016
L + +E T+ +++ E+ +++ + K+ L ++ L DLQA+ ++
Sbjct: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQADSEES 1421
Query: 1017 ---VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK 1073
+ L K +L ++ D + LE ++ +LE+ +R+ + +L E + + +K
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREK 1478
Query: 1074 QQLDERLKKKDF---ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Q ++ ++KD E +L ++E++ + +K+ L+A ++++ + + + A
Sbjct: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Query: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
KV+K DL ++++ E L+E G + LE+A L+ E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEME 1580
Query: 1191 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
+R+ H+ + E++ + +Q +K+ + +++L++ + +++++ K LE
Sbjct: 1581 RMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
Query: 1251 TLEDQMNEHRSKAEETQRS--------------VNDLTSQRAKLQTENGELSRQLDEKEA 1296
TL DQ+N ++E+ R + D A + E +L QL+E E
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
Query: 1297 LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1356
+ + + ++EDL Q+++ KAK AL L + + + ++ + EE+ E +
Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE---D 1754
Query: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
+ ++ K + VAQ A + LAQ + + + +E N + L++
Sbjct: 1755 MNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQE 1795
Query: 1417 TKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1476
LQ+++E L E+S + + +++ + E + + E +++++ + A
Sbjct: 1796 KLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLESLASR 1847
Query: 1477 LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA- 1535
L + KL ++ + K +NK LQ ++ D E++G E RK+ EA
Sbjct: 1848 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMG---------ELARKEAEAS 1898
Query: 1536 -EKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1582
+K EL+ LE EA+ + + + A ++A IE ++ + E
Sbjct: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENE 1946
Score = 193 bits (490), Expect = 2e-48
Identities = 178/797 (22%), Positives = 373/797 (46%), Gaps = 39/797 (4%)
Query: 1138 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1192
D R +EE+ E LE++ G + V E Q+ + TL A L
Sbjct: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
Query: 1193 RKKHADSVAELGEQIDNL--QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
++H +I +L + V++ ++K K + + + +I+ + + E+ R
Sbjct: 1204 ARQHFKK-----RKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIR 1257
Query: 1251 TLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL-DEKEA------LISQLTR 1303
++++ + RSK E+ ++ N+L +L++ EL+ +L DE+ L+ T
Sbjct: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
Query: 1304 GKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1363
+L +++++L+ Q + K + + AR ++ +A E + +
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
Query: 1364 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423
A EV + + + + + E ++ K++L +RL + + E L+K RL
Sbjct: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
Query: 1424 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1483
E++D + +E L+KKQR FD L++ ++ + + + E Q+E L E F
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
LK EE + F ++ +L+ E+ D++ Q ++ +++K + LEA+ + +
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
Query: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
L+E +++ E LR ++E +++ +++ +DEE+E+A+++ + + ++ L+
Sbjct: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
E + + LR K+++EG L + Q+ NR E++K+ L+ LK T+ L DA
Sbjct: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
Query: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
D LK N A +R L+ +LEE ++RK E E+ + ++ + T+L
Sbjct: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
Query: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1780
Q ++ + +++Q +EE ++ +K K A+ A + +L + D A LE
Sbjct: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
Query: 1781 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGM 1840
+ K+ +++ ++ LQ +++ EQ + K + + EA++RELE LE E+ + VK +
Sbjct: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
Query: 1841 RKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1900
R+KE + E+R + ++ + +++ R +E + ++ + +
Sbjct: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
Query: 1901 HELDEAEERADIAESQV 1917
HEL+ E + A +
Sbjct: 1902 HELEMDLESLEAANQSL 1918
Score = 169 bits (428), Expect = 2e-41
Identities = 196/849 (23%), Positives = 392/849 (46%), Gaps = 87/849 (10%)
Query: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH----QQALDDLQAEED 1015
TLA++E+++ E +NLT A +A+ +K+ +Q+ Q+ + + +D
Sbjct: 1176 TLARLEEQRD--EQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233
Query: 1016 ----KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN 1071
K+ T + ++++ + + E+ +++R LE+A+++ +L+L + LE+
Sbjct: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKE-RNELRLNSDR---LES 1289
Query: 1072 DKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
+L L + + + ++ E A + +K++KELQ + + L++++E +
Sbjct: 1290 RISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
Query: 1132 VEKLRS-DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR--RDLEEATLQHEAT 1188
+R+ +++ E+++ ++AGG ++ E RE +F K R ++ E+ +
Sbjct: 1350 ARLIRAAEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEVEQQN 1403
Query: 1189 AAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM 1248
L ++ D A+ E QR Q+L+K+ EL D ++E LEK
Sbjct: 1404 KRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
Query: 1249 CRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTY 1308
R + ++++ +A+ + L ++ L E L +QL+EK+ I+ T+ ++
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
Query: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN--- 1365
+L+D+ Q E K + +LA + R D + + EEE + +A ++L +A
Sbjct: 1520 EAELQDISSQ---ESKDEASLAKVKKQLR-DLEAKVKDQEEELDEQAGTIQMLEQAKLRL 1575
Query: 1366 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424
E+ + R + + R EE+EEA++ ++L++ E +E + + K L+ +
Sbjct: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
Query: 1425 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 1484
+ L V R + + ++ K L K ++Q L+ + A S E+ +L
Sbjct: 1636 LATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-KREIAQL 1688
Query: 1485 KNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSAL 1544
KN EES + K ++ EI DL Q+ K LE+ +L+ EK E+Q+ L
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
Query: 1545 EE----------------AEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAK 1587
EE A+AS + + L+AQLE N+ K E++ KL ++E +
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1808
Query: 1588 RNHL---------RVVDSLQTSLDAET----RSRNEALRVKKKMEGDLNEMEIQLSHANR 1634
++ + + L+T L+ E R + A R+K+ ME E + +++ NR
Sbjct: 1809 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENR 1868
Query: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
++Q K LQ L+DT+ ++ + R A R+ + L+ +LE L A +
Sbjct: 1869 ----EKEQNKRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLESLEAANQS 1917
Query: 1695 TERSRKLAEQEL--IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
+ KLA + + ++ + ++ +N LIN + D D S+L+ V + V+ +
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD-SELEDRV-DGVKSWLSKN 1975
Query: 1753 EKAKKAITD 1761
+ KA +D
Sbjct: 1976 KGPSKAASD 1984
Score = 118 bits (296), Expect = 5e-26
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 68/594 (11%)
Query: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT---KYETDAIQRTEELEEAKK--KL 1393
+ L EQ + E +L+ L KA E + R + E+ + T EL + + +
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 1394 AQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452
A +L +AE A + L+ L+ ++E + ++V + AA + + D
Sbjct: 1308 ASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDA 1367
Query: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
EW+ KYE + E++ ++K +L+ +E+ LE + KR+ L+ + DL
Sbjct: 1368 GGEWRLKYERAVREVDFTKK----------RLQQEFEDKLEVEQQNKRQ---LERRLGDL 1414
Query: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
S + + +L+K ++L AE + + LE + E K R E +Q E
Sbjct: 1415 QADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA 1474
Query: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
+R+ ++ E++++ K L SL+ L+ + + +E +L ++ Q S
Sbjct: 1475 QREKLQR-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKD 1533
Query: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
A+ +KQ++ L++ +KD + +LD+ I ++E+ L+ E+E +R
Sbjct: 1534 EASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTH 1586
Query: 1693 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
+ SR ++E+ E + Q + K+M+ L + + ++ ++E R E
Sbjct: 1587 SKEMESR---DEEVEEARQSCQ----------KKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 1753 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGK 1809
K A +++++ + S +R++K++++T + D Q LD + A
Sbjct: 1634 GKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS--- 1681
Query: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
+ + +L+N+LE + A +VK + E I++L Q ++ K L++ +
Sbjct: 1682 ------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
Query: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923
+LQ + + + EE +E N + K H+ A+ D+A Q+N L+A+
Sbjct: 1736 RLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQ 1782
Score = 80.1 bits (196), Expect = 2e-14
Identities = 68/319 (21%), Positives = 154/319 (48%), Gaps = 18/319 (5%)
Query: 1625 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
+E+QLS ++Q+++ ++ + +L+ A + ++L+ N +E R + L +E
Sbjct: 1247 IEVQLS---------EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSE 1297
Query: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ----TE 1740
L + R E + E + + ++ L +Q +L Q + M+ ++ + + E
Sbjct: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
Query: 1741 VEEAVQECRNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTIKDLQHR 1796
+ V + E K ++A+ + + L++E + +E+ K+ +E+ + DLQ
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
Query: 1797 LDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1856
+E+++ AL+ KK+ Q+L A +++ + LE +Q RN E K R+ + + + + +
Sbjct: 1418 SEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
Query: 1857 DRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1916
++ +LQ D L + + K+Q EE + K ++ EL + + E+
Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
Query: 1917 VNKLRAKSRDIGTKGLNEE 1935
+ K++ + RD+ K ++E
Sbjct: 1537 LAKVKKQLRDLEAKVKDQE 1555
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 489 bits (1260), Expect = e-138
Identities = 319/959 (33%), Positives = 526/959 (54%), Gaps = 50/959 (5%)
Query: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQ-----NPPKFDKIEDMA 91
V++ ++ Q F + + S G V T+YG+ T K+ + Q +P + ++DMA
Sbjct: 11 VWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMA 69
Query: 92 MLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLP-VYTPEVVAAYRGKKRSEA 150
LT LH +++YNL RY IYTY G +VNPY+ + +Y P + Y + E
Sbjct: 70 SLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGEL 129
Query: 151 PPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIG-DRSKKDQ 209
PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ +VI+ + S K++
Sbjct: 130 PPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKEK 189
Query: 210 SPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 269
+ +E I++++P +EAFGNAKTV N+NSSRFGKF++++ G + I YLLE
Sbjct: 190 T---SCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLE 246
Query: 270 KSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQ-GETTVASIDDAEE 328
K+RV+ Q ER+YHIFY +L+ + E + + + P +Y +++Q G +I D E
Sbjct: 247 KNRVVRQNPGERNYHIFYALLAGLEHEEREEFYL-STPENYHYLNQSGCVEDKTISDQES 305
Query: 329 LMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLM 388
A DV+ F+ EE + +L I+H GN++F A+ +SA L+
Sbjct: 306 FREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELL 362
Query: 389 GLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE 448
GL+ L L + + E + NVQQ + + +LA A+Y F W++ +IN+ ++
Sbjct: 363 GLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIK 422
Query: 449 TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 508
+ + IG+LDI GFE F+ N FEQ IN+ NEKLQ++FN H+F LEQ EY +EG+ W
Sbjct: 423 GNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVW 481
Query: 509 TFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRN 568
ID+ +D C+DLIEK +G+++++ EE FP+ATD T KL H + + KPR
Sbjct: 482 EDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNHFYVKPRV 539
Query: 569 IKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGAD 628
+F + HYAG V Y++ G L+KN+D + ++ L ++S + LF + +
Sbjct: 540 AVN----NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSS-- 593
Query: 629 APIEKGKGKAKKGSSFQ--TVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDN 686
+ K GS + TVS+ +++L+ LM L S++P FVRCI PN K P D
Sbjct: 594 ---RNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQ 650
Query: 687 PLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL-NPAAIPEGQFIDSRKGAEKL 745
+V++QLR +G+LE +RI + G+ R + DF +RY++L A+PE D R L
Sbjct: 651 AVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----DVRGKCTSL 706
Query: 746 LSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLL 805
L D +++++ G TKVF + L LE+ R+E +S I+A G LAR +Y+K+L
Sbjct: 707 LQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL 766
Query: 806 ERRDSLLVIQWNIRAFMGVKNWPWM-KLYFKIKPLLKSAEREKEMASMKEEFTRLKEALE 864
+++IQ N RAF+ + + + K + L+ + + E +E +
Sbjct: 767 Y---CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKK 823
Query: 865 KSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNE 924
+ E +K+ EE+ +E+ + +L+ Q E++ E Q + + +L ++++ E
Sbjct: 824 QEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE 883
Query: 925 RLEDEEEMNAELTAKKRKLEDECSELKR--DIDDLELTLAKVEKEKHATENKVKNLTEE 981
+ EE + +LE E +L+R + +L LT A ++K + + +++ L EE
Sbjct: 884 NKQVEEIL---------RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEE 933
Score = 48.5 bits (114), Expect = 6e-05
Identities = 58/247 (23%), Positives = 103/247 (41%), Gaps = 26/247 (10%)
Query: 1267 QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK 1326
Q++ +R L + + Q + + ++ R L ++ E+ K+Q EEE K +
Sbjct: 773 QKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKR 832
Query: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEEL 1386
+ R + + LR Q EEET + EL+ L K+ E R + ++ EE+
Sbjct: 833 EEEERERERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEI 890
Query: 1387 EEAKKKL--AQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 1444
+K++ QR++E +E ++ +SL+K + R E+ L E AA
Sbjct: 891 LRLEKEIEDLQRMKEQQE----LSLTEASLQKLQERRDQELRRL----EEEACRAAQEFL 942
Query: 1445 KQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1504
+ NFD+I +E +E S S+EL E + E F
Sbjct: 943 ESLNFDEI--------DECVRNIERSLSVGSEFSSEL------AESACEEKPNFNFSQPY 988
Query: 1505 LQEEISD 1511
+EE+ +
Sbjct: 989 PEEEVDE 995
Score = 46.6 bits (109), Expect = 2e-04
Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 20/178 (11%)
Query: 1041 EKKVRMDL-ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
+K++R + R R+L + + +E E +K++ +E ++++ E R + E+
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855
Query: 1100 LGSQ-----LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG 1154
Q LQK KE EL ELE ++ + E LR L +E+E++ +R++E
Sbjct: 856 TRKQQELEALQKSQKE-----AELTRELEKQKENKQVEEILR--LEKEIEDL-QRMKEQQ 907
Query: 1155 GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR 1212
+ + + K +E RRD E L+ EA AA + + E+ E + N++R
Sbjct: 908 ELSLTEASLQKLQE------RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER 959
Score = 42.0 bits (97), Expect = 0.006
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 1816 EARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKV 1875
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
Query: 1876 KAYKRQAEEAEEQANTNLSKFRKVQHELDE-----AEERADIAESQVNKLRAKSRDIGTK 1930
K + E +++ N + + +++ E+++ ++ + E+ + KL+ + RD +
Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER-RDQELR 928
Query: 1931 GLNEE 1935
L EE
Sbjct: 929 RLEEE 933
Score = 40.4 bits (93), Expect = 0.017
Identities = 51/222 (22%), Positives = 95/222 (42%), Gaps = 30/222 (13%)
Query: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322
AE+ ++ + K + E E R+ + +EA +L+ Q EEE
Sbjct: 813 AEKREQEEKKKQEEEEKKKREEEERERERERREA-----------------ELRAQQEEE 855
Query: 1323 VKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
+ + L ALQ ++ + +L RE E++ E K +++ +L + E+ + E +
Sbjct: 856 TRKQQEL-EALQKSQKEAELTRE-LEKQKENK-QVEEIL-RLEKEIEDLQRMKEQQELSL 911
Query: 1383 TE-ELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
TE L++ +++ Q L+ EE EA A LE +EI++ + ++ERS + +
Sbjct: 912 TEASLQKLQERRDQELRRLEE--EACRAAQEFLESLNF---DEIDECVRNIERSLSVGSE 966
Query: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1483
+ + E K + SQ E E + FK
Sbjct: 967 FSSE---LAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFK 1005
Score = 39.3 bits (90), Expect = 0.038
Identities = 52/273 (19%), Positives = 124/273 (45%), Gaps = 40/273 (14%)
Query: 1073 KQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEA-------- 1124
++ L+++L+K+ E + A + LG +K+ +++ + +++ A
Sbjct: 727 RESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFL 786
Query: 1125 --ERTARAKVEKLRSDLSREL--EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1180
++ A ++LR ++R + + ++E+ E+ KK++ E +K +R+ EE
Sbjct: 787 HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQE----------EKKKQEEEEKKKREEEE 836
Query: 1181 ATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK 1240
+ E A LR + + + Q+ + L+K + E +L T +E+ K
Sbjct: 837 RERERERREAELRAQQEEETRK--------QQELEALQKSQKEAEL-----TRELEK-QK 882
Query: 1241 AKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQ 1300
+E++ R LE ++ + + E+ + S+ + + Q KLQ + R+L+E+ +Q
Sbjct: 883 ENKQVEEILR-LEKEIEDLQRMKEQQELSLTEASLQ--KLQERRDQELRRLEEEACRAAQ 939
Query: 1301 LTRGKLTYTQQLEDLKRQLEEEVKAKNALAHAL 1333
L + ++++ R +E + + + L
Sbjct: 940 EFLESLNF-DEIDECVRNIERSLSVGSEFSSEL 971
Score = 37.7 bits (86), Expect = 0.11
Identities = 42/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)
Query: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503
++Q K E K+K EE + E E ++EA +L+ EE + + K
Sbjct: 816 REQEEKKKQEEEEKKKREEEERERERERREA--------ELRAQQEEETRKQQELEALQK 867
Query: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
+ +E ++LT +L E +K KQ+E E + L+ +E+ + E +E + A L
Sbjct: 868 SQKE--AELTREL--------EKQKENKQVE-EILRLEKEIEDLQRMKEQQELSLTEASL 916
Query: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
+ +++ +++L +EE +A + L ++ +D R+ +L V + +L
Sbjct: 917 Q--KLQERRDQELRRLEEEACRAAQEFLESLNF--DEIDECVRNIERSLSVGSEFSSELA 972
Query: 1624 E 1624
E
Sbjct: 973 E 973
Score = 36.6 bits (83), Expect = 0.24
Identities = 53/230 (23%), Positives = 108/230 (46%), Gaps = 25/230 (10%)
Query: 1686 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAV 1745
++LR + + + LAE+ E ++ + + ++++ + ++L+ + EE
Sbjct: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET 856
Query: 1746 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAL 1805
+ + E +A + A + EL+K+++ E ++ +E+ I+DLQ R+ E ++++L
Sbjct: 857 R--KQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQ-RMKEQQELSL 911
Query: 1806 KGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTY-QTEEDRKNLLRL 1864
+ LQKL+ R + LE E R A+ ++ L + + +E +N+ R
Sbjct: 912 T--EASLQKLQERRDQELRRLEEEACRAAQEF---------LESLNFDEIDECVRNIER- 959
Query: 1865 QDLVDKLQLKVKAYKRQAEEA-EEQANTNLSKFRKVQHELDEAEERADIA 1913
L + + AE A EE+ N N S+ + E+DE E D A
Sbjct: 960 -----SLSVGSEFSSELAESACEEKPNFNFSQ-PYPEEEVDEGFEADDDA 1003
Score = 36.6 bits (83), Expect = 0.24
Identities = 46/210 (21%), Positives = 92/210 (43%), Gaps = 41/210 (19%)
Query: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Q E + K EE +R + + A+L+ + E +R+ E EAL +LT + +
Sbjct: 824 QEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
Query: 1315 LKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374
+Q+EE ++ L+ D ++EQ +E + +A LQ++ + + E
Sbjct: 883 ENKQVEEILR--------LEKEIEDLQRMKEQ-QELSLTEASLQKLQERRDQE------- 926
Query: 1375 YETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
++R EE + + A+E +E++N ++ ++N L V E
Sbjct: 927 -----LRRLEE---------EACRAAQEFLESLN-----FDEIDECVRNIERSLSVGSEF 967
Query: 1435 SNAAAAALDKKQRNFDKILAEWKQKYEESQ 1464
S+ A + +++ NF+ + Q Y E +
Sbjct: 968 SSELAESACEEKPNFN-----FSQPYPEEE 992
Score = 35.0 bits (79), Expect = 0.71
Identities = 60/250 (24%), Positives = 105/250 (42%), Gaps = 35/250 (14%)
Query: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
+V +QL AEK E +E + E EE K + E + + E ER+ AE + E+
Sbjct: 806 RVYRQLLAEKRE-----QEEKKKQEEEEKK----KREEEERERERERREAELRAQQEEET 856
Query: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
R Q L+A +S+ EA + +++E +++ +K+++ LQ
Sbjct: 857 RK--------QQELEALQKSQKEA-ELTRELEKQKENKQVE------EILRLEKEIEDLQ 901
Query: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI 1707
+ + ++ L +A + L+E R L + E E RA E E E +
Sbjct: 902 RMKEQQELSLTEA--SLQKLQE-----RRDQELRRLEEEACRAAQEFLESLNFDEIDECV 954
Query: 1708 ETSERVQLLHSQ-NTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
ER + S+ ++ L + + + Q EE V E A++ A K D+ +
Sbjct: 955 RNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFK---DSPNPS 1011
Query: 1767 EELKKEQDTS 1776
E +Q TS
Sbjct: 1012 EHGHSDQRTS 1021
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 483 bits (1243), Expect = e-136
Identities = 330/924 (35%), Positives = 495/924 (53%), Gaps = 67/924 (7%)
Query: 76 VMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYT 135
+ +P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+
Sbjct: 56 IKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYS 115
Query: 136 PEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYF 195
PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+
Sbjct: 116 PEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL 175
Query: 196 AVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGAT 255
A I+ G S +E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 176 AAIS--GQHS---------WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
Query: 256 GKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQ 315
G + A IE YLLEKSRV Q ER+YH+FY +L + L + DY +++
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283
Query: 316 GE-TTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQRE--EQ 372
G T D++E +A VL FT E + KL AI+H GN++++ + E +
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343
Query: 373 AEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVY 432
E + +A L+ +N DL+ L + E V+ + +Q + A K +Y
Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403
Query: 433 ERMFNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQ 486
R+F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQ
Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
Query: 487 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATD 545
QFF H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD
Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTD 521
Query: 546 MTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETV 605
T KL H +AN+ P+N E F + H+AGIV Y G+L+KN+D L+ +
Sbjct: 522 TTMLHKLNSQH-KLNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDI 577
Query: 606 VGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRST 665
+ L S K + +F A + G K+ T+S+ + +L LM L +
Sbjct: 578 IQLVHSSRNKFIKQIF------QADVAMGAETRKRS---PTLSSQFKRSLELLMRTLGAC 628
Query: 666 HPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL 725
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 629 QPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL 688
Query: 726 NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRII 785
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 689 LPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRV 748
Query: 786 TRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKL-YFKIKPLLKSAE 844
+Q RG R + KL +++ +IQ + R KN+ M+L + +++ L +S +
Sbjct: 749 ILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK 805
Query: 845 REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
++ ++ + +A ++ RK ++ ++ L VQA + R
Sbjct: 806 LHQQYRLARQRIIQF-QARCRAYLVRKAFRHRLWAV--------LTVQAYARGM--IARR 854
Query: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKRDIDDLE 958
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L R+ + E
Sbjct: 855 LHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERE 912
Query: 959 LTLAKVEKEKHATENKVKNLTEEM 982
L KEK A K K L E+M
Sbjct: 913 L------KEKEAARRK-KELLEQM 929
Score = 34.7 bits (78), Expect = 0.93
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1584
E EK+RK++ A+K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Query: 1585 QAKR---NHLRVVDSL 1597
+A+ NH +VD +
Sbjct: 931 RARHEPVNHSDMVDKM 946
Score = 33.9 bits (76), Expect = 1.6
Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 22/203 (10%)
Query: 753 HNQYKFGHTKVF-FKAGLLG-LLEEMRDERLSRIITRIQAQSRGVLARMEYKKL------ 804
H QY+ ++ F+A L+ + RL ++T +QA +RG++AR +++L
Sbjct: 807 HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLT-VQAYARGMIARRLHQRLRAEYLW 865
Query: 805 -LERRDSLLVIQWNIRAFMGVKNWPW---MKLYFKIKPLLKS-AERE---KEMASMKEEF 856
LE L + +R M K K ++ L + AERE KE A K+E
Sbjct: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKEL 925
Query: 857 TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLE 916
E ++ +KM L L Q D E ++++ +
Sbjct: 926 LEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAA 985
Query: 917 AKVKEMNERLEDEEEMNAELTAK 939
+ + EDEE+++ AK
Sbjct: 986 LPLPD-----EDEEDLSEYKFAK 1003
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 483 bits (1243), Expect = e-136
Identities = 330/924 (35%), Positives = 495/924 (53%), Gaps = 67/924 (7%)
Query: 76 VMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYT 135
+ +P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+
Sbjct: 56 IKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYS 115
Query: 136 PEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYF 195
PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+
Sbjct: 116 PEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL 175
Query: 196 AVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGAT 255
A I+ G S +E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 176 AAIS--GQHS---------WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
Query: 256 GKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQ 315
G + A IE YLLEKSRV Q ER+YH+FY +L + L + DY +++
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283
Query: 316 GE-TTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQRE--EQ 372
G T D++E +A VL FT E + KL AI+H GN++++ + E +
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343
Query: 373 AEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVY 432
E + +A L+ +N DL+ L + E V+ + +Q + A K +Y
Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403
Query: 433 ERMFNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQ 486
R+F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQ
Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
Query: 487 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATD 545
QFF H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD
Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTD 521
Query: 546 MTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETV 605
T KL H +AN+ P+N E F + H+AGIV Y G+L+KN+D L+ +
Sbjct: 522 TTMLHKLNSQH-KLNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDI 577
Query: 606 VGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRST 665
+ L S K + +F A + G K+ T+S+ + +L LM L +
Sbjct: 578 IQLVHSSRNKFIKQIF------QADVAMGAETRKRS---PTLSSQFKRSLELLMRTLGAC 628
Query: 666 HPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL 725
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 629 QPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL 688
Query: 726 NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRII 785
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 689 LPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRV 748
Query: 786 TRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKL-YFKIKPLLKSAE 844
+Q RG R + KL +++ +IQ + R KN+ M+L + +++ L +S +
Sbjct: 749 ILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK 805
Query: 845 REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
++ ++ + +A ++ RK ++ ++ L VQA + R
Sbjct: 806 LHQQYRLARQRIIQF-QARCRAYLVRKAFRHRLWAV--------LTVQAYARGM--IARR 854
Query: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKRDIDDLE 958
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L R+ + E
Sbjct: 855 LHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERE 912
Query: 959 LTLAKVEKEKHATENKVKNLTEEM 982
L KEK A K K L E+M
Sbjct: 913 L------KEKEAARRK-KELLEQM 929
Score = 34.7 bits (78), Expect = 0.93
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1584
E EK+RK++ A+K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Query: 1585 QAKR---NHLRVVDSL 1597
+A+ NH +VD +
Sbjct: 931 RARHEPVNHSDMVDKM 946
Score = 33.9 bits (76), Expect = 1.6
Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 22/203 (10%)
Query: 753 HNQYKFGHTKVF-FKAGLLG-LLEEMRDERLSRIITRIQAQSRGVLARMEYKKL------ 804
H QY+ ++ F+A L+ + RL ++T +QA +RG++AR +++L
Sbjct: 807 HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLT-VQAYARGMIARRLHQRLRAEYLW 865
Query: 805 -LERRDSLLVIQWNIRAFMGVKNWPW---MKLYFKIKPLLKS-AERE---KEMASMKEEF 856
LE L + +R M K K ++ L + AERE KE A K+E
Sbjct: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKEL 925
Query: 857 TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLE 916
E ++ +KM L L Q D E ++++ +
Sbjct: 926 LEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAA 985
Query: 917 AKVKEMNERLEDEEEMNAELTAK 939
+ + EDEE+++ AK
Sbjct: 986 LPLPD-----EDEEDLSEYKFAK 1003
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 483 bits (1243), Expect = e-136
Identities = 330/924 (35%), Positives = 495/924 (53%), Gaps = 67/924 (7%)
Query: 76 VMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYT 135
+ +P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+
Sbjct: 56 IKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYS 115
Query: 136 PEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYF 195
PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+
Sbjct: 116 PEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL 175
Query: 196 AVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGAT 255
A I+ G S +E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 176 AAIS--GQHS---------WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
Query: 256 GKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQ 315
G + A IE YLLEKSRV Q ER+YH+FY +L + L + DY +++
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283
Query: 316 GE-TTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQRE--EQ 372
G T D++E +A VL FT E + KL AI+H GN++++ + E +
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343
Query: 373 AEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVY 432
E + +A L+ +N DL+ L + E V+ + +Q + A K +Y
Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403
Query: 433 ERMFNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQ 486
R+F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQ
Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
Query: 487 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATD 545
QFF H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD
Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTD 521
Query: 546 MTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETV 605
T KL H +AN+ P+N E F + H+AGIV Y G+L+KN+D L+ +
Sbjct: 522 TTMLHKLNSQH-KLNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDI 577
Query: 606 VGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRST 665
+ L S K + +F A + G K+ T+S+ + +L LM L +
Sbjct: 578 IQLVHSSRNKFIKQIF------QADVAMGAETRKRS---PTLSSQFKRSLELLMRTLGAC 628
Query: 666 HPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL 725
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 629 QPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL 688
Query: 726 NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRII 785
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 689 LPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRV 748
Query: 786 TRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKL-YFKIKPLLKSAE 844
+Q RG R + KL +++ +IQ + R KN+ M+L + +++ L +S +
Sbjct: 749 ILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK 805
Query: 845 REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
++ ++ + +A ++ RK ++ ++ L VQA + R
Sbjct: 806 LHQQYRLARQRIIQF-QARCRAYLVRKAFRHRLWAV--------LTVQAYARGM--IARR 854
Query: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKRDIDDLE 958
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L R+ + E
Sbjct: 855 LHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERE 912
Query: 959 LTLAKVEKEKHATENKVKNLTEEM 982
L KEK A K K L E+M
Sbjct: 913 L------KEKEAARRK-KELLEQM 929
Score = 34.7 bits (78), Expect = 0.93
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1584
E EK+RK++ A+K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Query: 1585 QAKR---NHLRVVDSL 1597
+A+ NH +VD +
Sbjct: 931 RARHEPVNHSDMVDKM 946
Score = 33.9 bits (76), Expect = 1.6
Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 22/203 (10%)
Query: 753 HNQYKFGHTKVF-FKAGLLG-LLEEMRDERLSRIITRIQAQSRGVLARMEYKKL------ 804
H QY+ ++ F+A L+ + RL ++T +QA +RG++AR +++L
Sbjct: 807 HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLT-VQAYARGMIARRLHQRLRAEYLW 865
Query: 805 -LERRDSLLVIQWNIRAFMGVKNWPW---MKLYFKIKPLLKS-AERE---KEMASMKEEF 856
LE L + +R M K K ++ L + AERE KE A K+E
Sbjct: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKEL 925
Query: 857 TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLE 916
E ++ +KM L L Q D E ++++ +
Sbjct: 926 LEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAA 985
Query: 917 AKVKEMNERLEDEEEMNAELTAK 939
+ + EDEE+++ AK
Sbjct: 986 LPLPD-----EDEEDLSEYKFAK 1003
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,077,608
Number of Sequences: 37866
Number of extensions: 2880140
Number of successful extensions: 62717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 824
Number of HSP's successfully gapped in prelim test: 1587
Number of HSP's that attempted gapping in prelim test: 13469
Number of HSP's gapped (non-prelim): 15970
length of query: 1935
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1818
effective length of database: 13,817,196
effective search space: 25119662328
effective search space used: 25119662328
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.