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Search of human proteins with 224593275
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224593275 intermediate filament tail domain containing 1
isoform 4 [Homo sapiens]
(369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224593275 intermediate filament tail domain containing 1 isof... 740 0.0
gi|224593273 intermediate filament tail domain containing 1 isof... 720 0.0
gi|224593268 intermediate filament tail domain containing 1 isof... 662 0.0
gi|224593271 intermediate filament tail domain containing 1 isof... 525 e-149
gi|27436951 lamin B2 [Homo sapiens] 45 8e-05
gi|5031877 lamin B1 [Homo sapiens] 35 0.11
gi|5031875 lamin A/C isoform 2 [Homo sapiens] 35 0.14
gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens] 35 0.14
gi|27436948 lamin A/C isoform 3 [Homo sapiens] 34 0.18
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 33 0.31
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 33 0.31
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 33 0.31
gi|111955326 MLX interacting protein [Homo sapiens] 31 1.6
gi|9910266 kinesin family member 15 [Homo sapiens] 31 1.6
gi|27734829 hypothetical protein LOC256329 [Homo sapiens] 31 1.6
gi|148612838 hypothetical protein LOC158358 [Homo sapiens] 31 2.0
gi|224451082 cytospin A [Homo sapiens] 30 2.6
gi|224451080 cytospin A [Homo sapiens] 30 2.6
gi|229577185 epidermal growth factor receptor pathway substrate ... 30 2.6
gi|4503593 epidermal growth factor receptor pathway substrate 15... 30 2.6
gi|190014591 vestigial like 4 isoform b [Homo sapiens] 30 2.6
gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens] 30 4.5
gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens] 30 4.5
gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens] 30 4.5
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 30 4.5
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens] 30 4.5
gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens] 30 4.5
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens] 30 4.5
gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens] 30 4.5
gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens] 30 4.5
>gi|224593275 intermediate filament tail domain containing 1 isoform
4 [Homo sapiens]
Length = 369
Score = 740 bits (1910), Expect = 0.0
Identities = 369/369 (100%), Positives = 369/369 (100%)
Query: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS
Sbjct: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
Query: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI
Sbjct: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
Query: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF
Sbjct: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
Query: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTAIAWYTPIHWKQAW 240
VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTAIAWYTPIHWKQAW
Sbjct: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTAIAWYTPIHWKQAW 240
Query: 241 EKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKRE 300
EKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKRE
Sbjct: 241 EKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKRE 300
Query: 301 KEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKK 360
KEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKK
Sbjct: 301 KEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKK 360
Query: 361 KKTSESQKQ 369
KKTSESQKQ
Sbjct: 361 KKTSESQKQ 369
>gi|224593273 intermediate filament tail domain containing 1 isoform
1 [Homo sapiens]
Length = 409
Score = 720 bits (1859), Expect = 0.0
Identities = 369/409 (90%), Positives = 369/409 (90%), Gaps = 40/409 (9%)
Query: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS
Sbjct: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
Query: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI
Sbjct: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
Query: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF
Sbjct: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
Query: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT-------------- 226
VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT
Sbjct: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTVWAAASEAKHQPPS 240
Query: 227 --------------------------AIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR 260
AIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR
Sbjct: 241 DFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR 300
Query: 261 KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV 320
KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV
Sbjct: 301 KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV 360
Query: 321 SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ 369
SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ
Sbjct: 361 SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ 409
>gi|224593268 intermediate filament tail domain containing 1 isoform
2 [Homo sapiens]
Length = 388
Score = 662 bits (1707), Expect = 0.0
Identities = 339/380 (89%), Positives = 340/380 (89%), Gaps = 40/380 (10%)
Query: 30 QREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTS 89
+REDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTS
Sbjct: 9 RREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTS 68
Query: 90 KATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLK 149
KATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLK
Sbjct: 69 KATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLK 128
Query: 150 YFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTIS 209
YFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTIS
Sbjct: 129 YFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTIS 188
Query: 210 LYRFLPNIVMQANSTVT----------------------------------------AIA 229
LYRFLPNIVMQANSTVT AIA
Sbjct: 189 LYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 248
Query: 230 WYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQ 289
WYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQ
Sbjct: 249 WYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQ 308
Query: 290 VEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRS 349
VEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRS
Sbjct: 309 VEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRS 368
Query: 350 TRPNRASGSKKKKTSESQKQ 369
TRPNRASGSKKKKTSESQKQ
Sbjct: 369 TRPNRASGSKKKKTSESQKQ 388
>gi|224593271 intermediate filament tail domain containing 1 isoform
3 [Homo sapiens]
Length = 325
Score = 525 bits (1351), Expect = e-149
Identities = 268/313 (85%), Positives = 270/313 (86%), Gaps = 40/313 (12%)
Query: 97 SRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILE 156
SRV+ +ASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILE
Sbjct: 13 SRVQTHHNASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILE 72
Query: 157 EVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPN 216
EVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPN
Sbjct: 73 EVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPN 132
Query: 217 IVMQANSTVT----------------------------------------AIAWYTPIHW 236
IVMQANSTVT AIAWYTPIHW
Sbjct: 133 IVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHW 192
Query: 237 KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVL 296
KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVL
Sbjct: 193 KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVL 252
Query: 297 LKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRAS 356
LKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRAS
Sbjct: 253 LKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRAS 312
Query: 357 GSKKKKTSESQKQ 369
GSKKKKTSESQKQ
Sbjct: 313 GSKKKKTSESQKQ 325
>gi|27436951 lamin B2 [Homo sapiens]
Length = 600
Score = 45.4 bits (106), Expect = 8e-05
Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 51/226 (22%)
Query: 5 QDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSG 64
Q++ E MQ ++ E ++ + + + ++ Y K+L L LS S SS
Sbjct: 338 QEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYR------KLLEGEEERLKLSPSPSSR 391
Query: 65 MPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMIGDGE 124
+ +SR T S++G L++ +G R K+ + +G G
Sbjct: 392 VT---------VSRATSSSSGSLSATGRLGRSKR-------------KRLEVEEPLGSGP 429
Query: 125 DYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLI 184
S+ G + + Q+ +S+ G V I E++++G FV+L
Sbjct: 430 ----SVLGTGTGGSGGFHLAQQ----------------ASASGSVSIEEIDLEGKFVQLK 469
Query: 185 NSSLDKEMAIGD-HILQQNVNGQTISLYRFLPNIVMQANSTVTAIA 229
N+S DK+ ++G+ I +Q + G+ I+ Y+F P +++A VT A
Sbjct: 470 NNS-DKDQSLGNWRIKRQVLEGEEIA-YKFTPKYILRAGQMVTVWA 513
>gi|5031877 lamin B1 [Homo sapiens]
Length = 586
Score = 35.0 bits (79), Expect = 0.11
Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Query: 162 TSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQA 221
++S+ G+V I E++V G F++L N+S +++ +G + + + ++S Y++ V++A
Sbjct: 435 SASATGNVCIEEIDVDGKFIRLKNTS-EQDQPMGGWEMIRKIGDTSVS-YKYTSRYVLKA 492
Query: 222 NSTVT 226
TVT
Sbjct: 493 GQTVT 497
>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
Length = 572
Score = 34.7 bits (78), Expect = 0.14
Identities = 29/132 (21%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 167 GDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
G V + EV+ +G FV+L N S +++ ++G+ +++ + YRF P ++A VT
Sbjct: 438 GRVAVEEVDEEGKFVRLRNKS-NEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT 496
Query: 227 -----AIAWYTP---IHWK--QAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKE 276
A A ++P + WK W ++ R ++++ T + + + T+ ++
Sbjct: 497 IWAAGAGATHSPPTDLVWKAQNTWGCGNS----LRTALINSTGEEVAMRKLVRSVTVVED 552
Query: 277 KQDQPKKDISNY 288
+D+ D+ ++
Sbjct: 553 DEDEDGDDLLHH 564
>gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]
Length = 664
Score = 34.7 bits (78), Expect = 0.14
Identities = 29/132 (21%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 167 GDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
G V + EV+ +G FV+L N S +++ ++G+ +++ + YRF P ++A VT
Sbjct: 438 GRVAVEEVDEEGKFVRLRNKS-NEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT 496
Query: 227 -----AIAWYTP---IHWK--QAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKE 276
A A ++P + WK W ++ R ++++ T + + + T+ ++
Sbjct: 497 IWAAGAGATHSPPTDLVWKAQNTWGCGNS----LRTALINSTGEEVAMRKLVRSVTVVED 552
Query: 277 KQDQPKKDISNY 288
+D+ D+ ++
Sbjct: 553 DEDEDGDDLLHH 564
>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
Length = 634
Score = 34.3 bits (77), Expect = 0.18
Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 167 GDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
G V + EV+ +G FV+L N S +++ ++G+ +++ + YRF P ++A VT
Sbjct: 438 GRVAVEEVDEEGKFVRLRNKS-NEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT 496
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
sapiens]
Length = 3667
Score = 33.5 bits (75), Expect = 0.31
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
Query: 194 IGDHILQQNVNGQTISLYRFLPNIVMQANSTVTAIAWYTPIHWKQAWEKLDADVEFNRCS 253
+GD I V G + + P + ANS TA +W P+ +A + + +
Sbjct: 156 VGDKIRYSCVTGYILDGH---PQLTCIANSVNTA-SWDFPVPICRAEDACGGTMRGSSGI 211
Query: 254 VVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVF 308
+ SP+F T TI E D +++Q+E+ L+ E PPT++
Sbjct: 212 ISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIW 266
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 33.5 bits (75), Expect = 0.31
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
Query: 194 IGDHILQQNVNGQTISLYRFLPNIVMQANSTVTAIAWYTPIHWKQAWEKLDADVEFNRCS 253
+GD I V G + + P + ANS TA +W P+ +A + + +
Sbjct: 196 VGDKIRYSCVTGYILDGH---PQLTCIANSVNTA-SWDFPVPICRAEDACGGTMRGSSGI 251
Query: 254 VVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVF 308
+ SP+F T TI E D +++Q+E+ L+ E PPT++
Sbjct: 252 ISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIW 306
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo
sapiens]
Length = 3707
Score = 33.5 bits (75), Expect = 0.31
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
Query: 194 IGDHILQQNVNGQTISLYRFLPNIVMQANSTVTAIAWYTPIHWKQAWEKLDADVEFNRCS 253
+GD I V G + + P + ANS TA +W P+ +A + + +
Sbjct: 196 VGDKIRYSCVTGYILDGH---PQLTCIANSVNTA-SWDFPVPICRAEDACGGTMRGSSGI 251
Query: 254 VVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVF 308
+ SP+F T TI E D +++Q+E+ L+ E PPT++
Sbjct: 252 ISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIW 306
>gi|111955326 MLX interacting protein [Homo sapiens]
Length = 919
Score = 31.2 bits (69), Expect = 1.6
Identities = 14/36 (38%), Positives = 23/36 (63%)
Query: 125 DYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQ 160
D SL ++ KLT+H+ QKT++Y + + +E GQ
Sbjct: 740 DMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQ 775
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 31.2 bits (69), Expect = 1.6
Identities = 15/38 (39%), Positives = 24/38 (63%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYS 39
++ + +QE A+Q K+ E+E KN K +Q DKL +S
Sbjct: 717 EELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHS 754
>gi|27734829 hypothetical protein LOC256329 [Homo sapiens]
Length = 634
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/58 (29%), Positives = 29/58 (50%)
Query: 169 VEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
++I V+ + FV++ N S + + +L+Q V G LYRF P ++ VT
Sbjct: 362 LKIVAVSCREKFVRIFNPSQESTADLSGMVLKQLVRGFPERLYRFPPGTLLAPRHHVT 419
>gi|148612838 hypothetical protein LOC158358 [Homo sapiens]
Length = 2103
Score = 30.8 bits (68), Expect = 2.0
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 49 GSVATTLPLSSSNSSGMPLGYYLSS-PQISRVTISTTGQLTS--KATVGSCSRVENSLDA 105
G+V+T LP ++ N + PL S+ PQ S + LT K + + +N++ A
Sbjct: 1158 GTVSTQLPNTAFNKTITPLSNISSARPQPLSPVTSVSNLLTPSVKTSQSEAGKAKNAVSA 1217
Query: 106 SPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKT 147
+ FS+P G +L G + ++ + + Q+T
Sbjct: 1218 ATFSLPSASPTISSTGQPLSSTTTLNGSTNPGSSFNCFAQQT 1259
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 30.4 bits (67), Expect = 2.6
Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 18/125 (14%)
Query: 6 DIQEASKAMQNKVHEQEDKNEK----------QKQREDKLGVYSLVHFSPKMLGSVATTL 55
+ QE ++ ++HE ++KNEK +KQ E++ VY+ ++ + L ++ +
Sbjct: 766 EAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGM 825
Query: 56 PLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENS-LDASPFSVPKKQ 114
LS +S+ S P + T+ + S+ + + + + L SP P
Sbjct: 826 GLSRRSSTS-------SEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAA 878
Query: 115 DESPM 119
SPM
Sbjct: 879 AVSPM 883
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 30.4 bits (67), Expect = 2.6
Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 18/125 (14%)
Query: 6 DIQEASKAMQNKVHEQEDKNEK----------QKQREDKLGVYSLVHFSPKMLGSVATTL 55
+ QE ++ ++HE ++KNEK +KQ E++ VY+ ++ + L ++ +
Sbjct: 766 EAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGM 825
Query: 56 PLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENS-LDASPFSVPKKQ 114
LS +S+ S P + T+ + S+ + + + + L SP P
Sbjct: 826 GLSRRSSTS-------SEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAA 878
Query: 115 DESPM 119
SPM
Sbjct: 879 AVSPM 883
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 30.4 bits (67), Expect = 2.6
Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 27/146 (18%)
Query: 5 QDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSG 64
QD Q+ +MQ K+ E +D Q +S+ ++ LS+S+S
Sbjct: 169 QDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSI------LVNGATDYCSLSTSSSET 222
Query: 65 MPLGYYL------------------SSPQISRVTISTTGQLTSKATVGSCSRVEN---SL 103
L ++ SSP++ ++ ++T+ T CS ++N S
Sbjct: 223 ANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSK 282
Query: 104 DASPFSVPKKQDESPMIGDGEDYFLS 129
+ PF+V P+ D+F S
Sbjct: 283 EEDPFNVDSSSLTGPVADTNLDFFQS 308
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 30.4 bits (67), Expect = 2.6
Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 27/146 (18%)
Query: 5 QDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSG 64
QD Q+ +MQ K+ E +D Q +S+ ++ LS+S+S
Sbjct: 483 QDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSI------LVNGATDYCSLSTSSSET 536
Query: 65 MPLGYYL------------------SSPQISRVTISTTGQLTSKATVGSCSRVEN---SL 103
L ++ SSP++ ++ ++T+ T CS ++N S
Sbjct: 537 ANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSK 596
Query: 104 DASPFSVPKKQDESPMIGDGEDYFLS 129
+ PF+V P+ D+F S
Sbjct: 597 EEDPFNVDSSSLTGPVADTNLDFFQS 622
>gi|190014591 vestigial like 4 isoform b [Homo sapiens]
Length = 290
Score = 30.4 bits (67), Expect = 2.6
Identities = 25/100 (25%), Positives = 35/100 (35%), Gaps = 12/100 (12%)
Query: 263 VFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPW-------- 314
V AS EK++ + Q L + PP + P++ +
Sbjct: 7 VLSRAASLVHADDEKREAALRGEPRIQTLPVASALSSHRTGPPPISPSKRKFSMEPGDED 66
Query: 315 --CQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRP 352
C N +VS + PH TA G R PR RS P
Sbjct: 67 LDCDNDHVSK--MSRIFNPHLNKTANGDCRRDPRERSRSP 104
>gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens]
Length = 459
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens]
Length = 211
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens]
Length = 420
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 51 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 110
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 111 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 148
>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
Length = 241
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens]
Length = 637
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
Length = 645
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens]
Length = 640
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens]
Length = 462
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,614,526
Number of Sequences: 37866
Number of extensions: 609135
Number of successful extensions: 2156
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2138
Number of HSP's gapped (non-prelim): 43
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.