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Search of human proteins with 224593273
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224593273 intermediate filament tail domain containing 1
isoform 1 [Homo sapiens]
(409 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224593273 intermediate filament tail domain containing 1 isof... 827 0.0
gi|224593268 intermediate filament tail domain containing 1 isof... 768 0.0
gi|224593275 intermediate filament tail domain containing 1 isof... 720 0.0
gi|224593271 intermediate filament tail domain containing 1 isof... 631 0.0
gi|27436951 lamin B2 [Homo sapiens] 78 1e-14
gi|5031875 lamin A/C isoform 2 [Homo sapiens] 68 2e-11
gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens] 68 2e-11
gi|5031877 lamin B1 [Homo sapiens] 65 8e-11
gi|27436948 lamin A/C isoform 3 [Homo sapiens] 65 8e-11
gi|27734829 hypothetical protein LOC256329 [Homo sapiens] 49 1e-05
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 32 0.80
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 32 0.80
gi|111955326 MLX interacting protein [Homo sapiens] 31 1.8
gi|9910266 kinesin family member 15 [Homo sapiens] 31 1.8
gi|148612838 hypothetical protein LOC158358 [Homo sapiens] 31 2.3
gi|224451082 cytospin A [Homo sapiens] 30 3.0
gi|224451080 cytospin A [Homo sapiens] 30 3.0
gi|229577185 epidermal growth factor receptor pathway substrate ... 30 3.0
gi|4503593 epidermal growth factor receptor pathway substrate 15... 30 3.0
gi|190014591 vestigial like 4 isoform b [Homo sapiens] 30 3.0
gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens] 30 5.2
gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens] 30 5.2
gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens] 30 5.2
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 30 5.2
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens] 30 5.2
gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens] 30 5.2
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens] 30 5.2
gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens] 30 5.2
gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens] 30 5.2
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 29 8.8
>gi|224593273 intermediate filament tail domain containing 1 isoform
1 [Homo sapiens]
Length = 409
Score = 827 bits (2135), Expect = 0.0
Identities = 409/409 (100%), Positives = 409/409 (100%)
Query: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS
Sbjct: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
Query: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI
Sbjct: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
Query: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF
Sbjct: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
Query: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTVWAAASEAKHQPPS 240
VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTVWAAASEAKHQPPS
Sbjct: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTVWAAASEAKHQPPS 240
Query: 241 DFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR 300
DFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR
Sbjct: 241 DFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR 300
Query: 301 KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV 360
KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV
Sbjct: 301 KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV 360
Query: 361 SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ 409
SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ
Sbjct: 361 SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ 409
>gi|224593268 intermediate filament tail domain containing 1 isoform
2 [Homo sapiens]
Length = 388
Score = 768 bits (1983), Expect = 0.0
Identities = 379/380 (99%), Positives = 380/380 (100%)
Query: 30 QREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTS 89
+REDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTS
Sbjct: 9 RREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTS 68
Query: 90 KATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLK 149
KATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLK
Sbjct: 69 KATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLK 128
Query: 150 YFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTIS 209
YFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTIS
Sbjct: 129 YFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTIS 188
Query: 210 LYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 269
LYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA
Sbjct: 189 LYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 248
Query: 270 WYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQ 329
WYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQ
Sbjct: 249 WYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQ 308
Query: 330 VEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRS 389
VEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRS
Sbjct: 309 VEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRS 368
Query: 390 TRPNRASGSKKKKTSESQKQ 409
TRPNRASGSKKKKTSESQKQ
Sbjct: 369 TRPNRASGSKKKKTSESQKQ 388
>gi|224593275 intermediate filament tail domain containing 1 isoform
4 [Homo sapiens]
Length = 369
Score = 720 bits (1859), Expect = 0.0
Identities = 369/409 (90%), Positives = 369/409 (90%), Gaps = 40/409 (9%)
Query: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS
Sbjct: 1 MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSS 60
Query: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI
Sbjct: 61 NSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMI 120
Query: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF
Sbjct: 121 GDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLF 180
Query: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTVWAAASEAKHQPPS 240
VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT
Sbjct: 181 VKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT-------------- 226
Query: 241 DFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR 300
AIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR
Sbjct: 227 --------------------------AIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFR 260
Query: 301 KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV 360
KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV
Sbjct: 261 KRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYV 320
Query: 361 SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ 409
SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ
Sbjct: 321 SAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSESQKQ 369
>gi|224593271 intermediate filament tail domain containing 1 isoform
3 [Homo sapiens]
Length = 325
Score = 631 bits (1627), Expect = 0.0
Identities = 308/313 (98%), Positives = 310/313 (99%)
Query: 97 SRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILE 156
SRV+ +ASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILE
Sbjct: 13 SRVQTHHNASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILE 72
Query: 157 EVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPN 216
EVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPN
Sbjct: 73 EVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPN 132
Query: 217 IVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHW 276
IVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHW
Sbjct: 133 IVMQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHW 192
Query: 277 KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVL 336
KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVL
Sbjct: 193 KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQVL 252
Query: 337 LKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRAS 396
LKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRAS
Sbjct: 253 LKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRAS 312
Query: 397 GSKKKKTSESQKQ 409
GSKKKKTSESQKQ
Sbjct: 313 GSKKKKTSESQKQ 325
>gi|27436951 lamin B2 [Homo sapiens]
Length = 600
Score = 78.2 bits (191), Expect = 1e-14
Identities = 68/269 (25%), Positives = 121/269 (44%), Gaps = 51/269 (18%)
Query: 5 QDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSG 64
Q++ E MQ ++ E ++ + + + ++ Y K+L L LS S SS
Sbjct: 338 QEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYR------KLLEGEEERLKLSPSPSSR 391
Query: 65 MPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMIGDGE 124
+ +SR T S++G L++ +G R K+ + +G G
Sbjct: 392 VT---------VSRATSSSSGSLSATGRLGRSKR-------------KRLEVEEPLGSGP 429
Query: 125 DYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLI 184
S+ G + + Q+ +S+ G V I E++++G FV+L
Sbjct: 430 ----SVLGTGTGGSGGFHLAQQ----------------ASASGSVSIEEIDLEGKFVQLK 469
Query: 185 NSSLDKEMAIGD-HILQQNVNGQTISLYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFL 243
N+S DK+ ++G+ I +Q + G+ I+ Y+F P +++A VTVWAA + H PPS +
Sbjct: 470 NNS-DKDQSLGNWRIKRQVLEGEEIA-YKFTPKYILRAGQMVTVWAAGAGVAHSPPSTLV 527
Query: 244 WKEQDKFRASPDCITILCKPNGQAIAWYT 272
WK Q + T+L +G+ +A T
Sbjct: 528 WKGQSSWGTGESFRTVLVNADGEEVAMRT 556
>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
Length = 572
Score = 67.8 bits (164), Expect = 2e-11
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Query: 167 GDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
G V + EV+ +G FV+L N S +++ ++G+ +++ + YRF P ++A VT
Sbjct: 438 GRVAVEEVDEEGKFVRLRNKS-NEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT 496
Query: 227 VWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 269
+WAA + A H PP+D +WK Q+ + T L G+ +A
Sbjct: 497 IWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVA 539
>gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]
Length = 664
Score = 67.8 bits (164), Expect = 2e-11
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Query: 167 GDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
G V + EV+ +G FV+L N S +++ ++G+ +++ + YRF P ++A VT
Sbjct: 438 GRVAVEEVDEEGKFVRLRNKS-NEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT 496
Query: 227 VWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 269
+WAA + A H PP+D +WK Q+ + T L G+ +A
Sbjct: 497 IWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVA 539
>gi|5031877 lamin B1 [Homo sapiens]
Length = 586
Score = 65.5 bits (158), Expect = 8e-11
Identities = 33/108 (30%), Positives = 63/108 (58%), Gaps = 2/108 (1%)
Query: 162 TSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQA 221
++S+ G+V I E++V G F++L N+S +++ +G + + + ++S Y++ V++A
Sbjct: 435 SASATGNVCIEEIDVDGKFIRLKNTS-EQDQPMGGWEMIRKIGDTSVS-YKYTSRYVLKA 492
Query: 222 NSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 269
TVT+WAA + PP+D +WK Q+ + D IL G+ +A
Sbjct: 493 GQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVA 540
>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
Length = 634
Score = 65.5 bits (158), Expect = 8e-11
Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Query: 167 GDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT 226
G V + EV+ +G FV+L N S +++ ++G+ +++ + YRF P ++A VT
Sbjct: 438 GRVAVEEVDEEGKFVRLRNKS-NEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT 496
Query: 227 VWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQ 266
+WAA + A H PP+D +WK Q+ + T L G+
Sbjct: 497 IWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGE 536
>gi|27734829 hypothetical protein LOC256329 [Homo sapiens]
Length = 634
Score = 48.5 bits (114), Expect = 1e-05
Identities = 27/101 (26%), Positives = 48/101 (47%)
Query: 169 VEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVTVW 228
++I V+ + FV++ N S + + +L+Q V G LYRF P ++ VTVW
Sbjct: 362 LKIVAVSCREKFVRIFNPSQESTADLSGMVLKQLVRGFPERLYRFPPGTLLAPRHHVTVW 421
Query: 229 AAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIA 269
A+ + +P +E + C T+L P G+ ++
Sbjct: 422 GEATRSAKKPLRASSSREPVPLLSIRGCATLLLSPKGEVLS 462
>gi|218505835 membrane-associated guanylate kinase-related 3
isoform 1 [Homo sapiens]
Length = 1481
Score = 32.3 bits (72), Expect = 0.80
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 12/85 (14%)
Query: 191 EMAIGDHILQQNVNGQTIS--LYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFLWKEQD 248
++ +GDHI VNGQ+I + + ++ A TVT+ A E H PPS +
Sbjct: 896 KLKVGDHI--SAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAEEEHHGPPSG-----TN 948
Query: 249 KFRASPDCITILCKPNGQAIAWYTP 273
R SP + +P GQ+ A + P
Sbjct: 949 SARQSP---ALQHRPMGQSQANHIP 970
>gi|155969695 membrane-associated guanylate kinase-related 3
isoform 2 [Homo sapiens]
Length = 1125
Score = 32.3 bits (72), Expect = 0.80
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 12/85 (14%)
Query: 191 EMAIGDHILQQNVNGQTIS--LYRFLPNIVMQANSTVTVWAAASEAKHQPPSDFLWKEQD 248
++ +GDHI VNGQ+I + + ++ A TVT+ A E H PPS +
Sbjct: 896 KLKVGDHI--SAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAEEEHHGPPSG-----TN 948
Query: 249 KFRASPDCITILCKPNGQAIAWYTP 273
R SP + +P GQ+ A + P
Sbjct: 949 SARQSP---ALQHRPMGQSQANHIP 970
>gi|111955326 MLX interacting protein [Homo sapiens]
Length = 919
Score = 31.2 bits (69), Expect = 1.8
Identities = 14/36 (38%), Positives = 23/36 (63%)
Query: 125 DYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQ 160
D SL ++ KLT+H+ QKT++Y + + +E GQ
Sbjct: 740 DMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQ 775
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 31.2 bits (69), Expect = 1.8
Identities = 15/38 (39%), Positives = 24/38 (63%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYS 39
++ + +QE A+Q K+ E+E KN K +Q DKL +S
Sbjct: 717 EELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHS 754
>gi|148612838 hypothetical protein LOC158358 [Homo sapiens]
Length = 2103
Score = 30.8 bits (68), Expect = 2.3
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 49 GSVATTLPLSSSNSSGMPLGYYLSS-PQISRVTISTTGQLTS--KATVGSCSRVENSLDA 105
G+V+T LP ++ N + PL S+ PQ S + LT K + + +N++ A
Sbjct: 1158 GTVSTQLPNTAFNKTITPLSNISSARPQPLSPVTSVSNLLTPSVKTSQSEAGKAKNAVSA 1217
Query: 106 SPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKT 147
+ FS+P G +L G + ++ + + Q+T
Sbjct: 1218 ATFSLPSASPTISSTGQPLSSTTTLNGSTNPGSSFNCFAQQT 1259
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 30.4 bits (67), Expect = 3.0
Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 18/125 (14%)
Query: 6 DIQEASKAMQNKVHEQEDKNEK----------QKQREDKLGVYSLVHFSPKMLGSVATTL 55
+ QE ++ ++HE ++KNEK +KQ E++ VY+ ++ + L ++ +
Sbjct: 766 EAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGM 825
Query: 56 PLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENS-LDASPFSVPKKQ 114
LS +S+ S P + T+ + S+ + + + + L SP P
Sbjct: 826 GLSRRSSTS-------SEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAA 878
Query: 115 DESPM 119
SPM
Sbjct: 879 AVSPM 883
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 30.4 bits (67), Expect = 3.0
Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 18/125 (14%)
Query: 6 DIQEASKAMQNKVHEQEDKNEK----------QKQREDKLGVYSLVHFSPKMLGSVATTL 55
+ QE ++ ++HE ++KNEK +KQ E++ VY+ ++ + L ++ +
Sbjct: 766 EAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGM 825
Query: 56 PLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENS-LDASPFSVPKKQ 114
LS +S+ S P + T+ + S+ + + + + L SP P
Sbjct: 826 GLSRRSSTS-------SEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAA 878
Query: 115 DESPM 119
SPM
Sbjct: 879 AVSPM 883
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 30.4 bits (67), Expect = 3.0
Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 27/146 (18%)
Query: 5 QDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSG 64
QD Q+ +MQ K+ E +D Q +S+ ++ LS+S+S
Sbjct: 169 QDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSI------LVNGATDYCSLSTSSSET 222
Query: 65 MPLGYYL------------------SSPQISRVTISTTGQLTSKATVGSCSRVEN---SL 103
L ++ SSP++ ++ ++T+ T CS ++N S
Sbjct: 223 ANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSK 282
Query: 104 DASPFSVPKKQDESPMIGDGEDYFLS 129
+ PF+V P+ D+F S
Sbjct: 283 EEDPFNVDSSSLTGPVADTNLDFFQS 308
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 30.4 bits (67), Expect = 3.0
Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 27/146 (18%)
Query: 5 QDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSNSSG 64
QD Q+ +MQ K+ E +D Q +S+ ++ LS+S+S
Sbjct: 483 QDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSI------LVNGATDYCSLSTSSSET 536
Query: 65 MPLGYYL------------------SSPQISRVTISTTGQLTSKATVGSCSRVEN---SL 103
L ++ SSP++ ++ ++T+ T CS ++N S
Sbjct: 537 ANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSK 596
Query: 104 DASPFSVPKKQDESPMIGDGEDYFLS 129
+ PF+V P+ D+F S
Sbjct: 597 EEDPFNVDSSSLTGPVADTNLDFFQS 622
>gi|190014591 vestigial like 4 isoform b [Homo sapiens]
Length = 290
Score = 30.4 bits (67), Expect = 3.0
Identities = 25/100 (25%), Positives = 35/100 (35%), Gaps = 12/100 (12%)
Query: 303 VFQWTASTATITKEKQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPW-------- 354
V AS EK++ + Q L + PP + P++ +
Sbjct: 7 VLSRAASLVHADDEKREAALRGEPRIQTLPVASALSSHRTGPPPISPSKRKFSMEPGDED 66
Query: 355 --CQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRP 392
C N +VS + PH TA G R PR RS P
Sbjct: 67 LDCDNDHVSK--MSRIFNPHLNKTANGDCRRDPRERSRSP 104
>gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens]
Length = 459
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens]
Length = 211
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens]
Length = 420
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 51 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 110
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 111 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 148
>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
Length = 241
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens]
Length = 637
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
Length = 645
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens]
Length = 640
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens]
Length = 462
Score = 29.6 bits (65), Expect = 5.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKL--GVYSLVHFSPKMLGSVATTLPLSS 59
K+ ++ +K K+ ++ K+E + + G Y S S + + +
Sbjct: 72 KNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
Query: 60 SNS--SGMPL---GYYLSSPQISRVTISTTGQLTSKAT 92
SN +GMP G Y+SS R+++ST G TS +T
Sbjct: 132 SNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSST 169
>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 28.9 bits (63), Expect = 8.8
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
Query: 2 KDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFSPKMLGSVATTLPLSSSN 61
KD D E SK ++ +EK + R+ +S S ++T SS
Sbjct: 32 KDRSD--EKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSST 89
Query: 62 SSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCS----RVENSLDASPFSVPKKQDE 116
S+G G SS + ST+ +S ++ GS S R +N + S P K+DE
Sbjct: 90 STGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDE 148
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,746,968
Number of Sequences: 37866
Number of extensions: 719873
Number of successful extensions: 2302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2277
Number of HSP's gapped (non-prelim): 41
length of query: 409
length of database: 18,247,518
effective HSP length: 105
effective length of query: 304
effective length of database: 14,271,588
effective search space: 4338562752
effective search space used: 4338562752
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.