Search of human proteins with 223972677

Search of human proteins with 223972677

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223972677 amidohydrolase domain containing 1 [Homo sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223972677 amidohydrolase domain containing 1 [Homo sapiens]        848   0.0  
gi|4758426 guanine deaminase [Homo sapiens]                            37   0.045
gi|4503375 dihydropyrimidinase [Homo sapiens]                          33   0.38 
gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens]      32   1.4  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    32   1.4  
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]            31   1.9  
gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]    31   1.9  
gi|4503379 dihydropyrimidinase-like 3 [Homo sapiens]                   31   2.4  
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]          30   4.2  
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]         30   4.2  
gi|38257139 protein kinase, cAMP-dependent, regulatory, type I, ...    29   7.1  
gi|31742505 Rho family guanine-nucleotide exchange factor [Homo ...    29   7.1  
gi|238908495 similar to pleckstrin homology domain protein (5V32...    29   9.3  

>gi|223972677 amidohydrolase domain containing 1 [Homo sapiens]
          Length = 426

 Score =  848 bits (2191), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQ 60
           MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQ
Sbjct: 1   MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQ 60

Query: 61  RQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIH 120
           RQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIH
Sbjct: 61  RQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIH 120

Query: 121 FTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARREL 180
           FTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARREL
Sbjct: 121 FTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARREL 180

Query: 181 DIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDL 240
           DIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDL
Sbjct: 181 DIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDL 240

Query: 241 DSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARC 300
           DSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARC
Sbjct: 241 DSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARC 300

Query: 301 SAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMP 360
           SAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMP
Sbjct: 301 SAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMP 360

Query: 361 EALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKG 420
           EALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKG
Sbjct: 361 EALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKG 420

Query: 421 KLIYKT 426
           KLIYKT
Sbjct: 421 KLIYKT 426


>gi|4758426 guanine deaminase [Homo sapiens]
          Length = 454

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 14/112 (12%)

Query: 321 KMLDEGVIVALGSDFNPNAYCFSM-------PMVMHLACVNM----RMSMPEALAAATIN 369
           ++L   V + LG+D     Y +SM        MV ++  +N      +++ E    AT+ 
Sbjct: 317 EVLKHEVKIGLGTDV-AGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLG 375

Query: 370 AAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHH--ELIEYVIAK 419
            + ALG     G+ EVGK+ D I+IN    +  I  F G    ++ E VI K
Sbjct: 376 GSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQK 427


>gi|4503375 dihydropyrimidinase [Homo sapiens]
          Length = 519

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)

Query: 43  VVGKDGFIKAIGPADVIQRQFSGETFEEIIDCSGKCILPGLVDAHTH---PVWAGERVHE 99
           V+ +DG ++A+G  D++    +      ++D +GK +LPG +D HTH   P      + +
Sbjct: 25  VLVEDGVVRALGH-DLLPPGGAPAGLR-VLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82

Query: 100 F----AMKLAGATYM----EIHQAGGGI 119
           F       L+G T M     I Q GG +
Sbjct: 83  FHQGTKAALSGGTTMIIDFAIPQKGGSL 110


>gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens]
          Length = 114

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 6/55 (10%)

Query: 373 ALGKSHTHGSLEVGKQ-----GDLIIINSSRWEHL-IYQFGGHHELIEYVIAKGK 421
           AL +S   G+LE+ K       D+ + N   W  L I  FGGH +++ Y+I K K
Sbjct: 54  ALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAK 108


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 39/169 (23%), Positives = 77/169 (45%), Gaps = 21/169 (12%)

Query: 123  VERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARRELDI 182
            ++ T Q T ++L ++ + ++  + +A T L +        LE E K+   +ERA+R+L+ 
Sbjct: 1002 LQETHQQTLDDL-QAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1060

Query: 183  GISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDN-IDVFCEKGVFDLD 241
             +             K A E+  D + N   +L E     E  + N I    ++   ++ 
Sbjct: 1061 DL-------------KLAQESTMD-MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQ 1106

Query: 242  STRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAIS-HLEEVSD 289
              ++I    K++  +I   G+E+   +A+   AE     +S  LEE+S+
Sbjct: 1107 LQKKI----KELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISE 1151


>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 34/156 (21%), Positives = 70/156 (44%), Gaps = 15/156 (9%)

Query: 170 LRVIERARRELDIGISATYCG------AHSVPKGKTATEAADDIINNHLPKLKELGRNGE 223
           L  +++  R+  +G+S T C       AH  P  K+  +  +D+  N   KL+E  R+  
Sbjct: 486 LHELKKGLRKYLLGLSDTECPEQKQVFAHPSPTQKSPVQPVEDLAGNLWEKLREKIRSFV 545

Query: 224 IHVDNIDVFCEKGVFDLDSTRR--ILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAI 281
            +   ID      + D+++T +  I  RG D    ++    +  PM   + G E+ ++  
Sbjct: 546 AYSIAID-----EITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVE 600

Query: 282 SHLEE--VSDEGIVAMATARCSAILLPTTAYMLRLK 315
             L++  +    +V++A+    A++      + +LK
Sbjct: 601 KSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLK 636


>gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]
          Length = 1241

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 31/141 (21%)

Query: 80  LPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIHFTVERTRQATEEELFRSLQ 139
           +  +++  T P  AGE++ EF++ L G  Y E  Q     H       Q  EEE    ++
Sbjct: 227 IENVIEEATKP--AGEQIAEFSIHLLGKQYREELQDSSSFH------HQHLEEEFISEVE 278

Query: 140 QRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIE-RARRELDIGISATYCGAHSVPKGK 198
                +            GY        K +RV+E R+ +E D G+   Y    +   G+
Sbjct: 279 NAFTGL-----------PGY--------KEIRVLEFRSPKENDSGVDVYYAVTFN---GE 316

Query: 199 TATEAADDIINNHLPKLKELG 219
             +    D+I+ H  K++  G
Sbjct: 317 AISNTTWDLISLHSNKVENHG 337


>gi|4503379 dihydropyrimidinase-like 3 [Homo sapiens]
          Length = 570

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 6/44 (13%)

Query: 46 KDGFIKAIGPADVIQRQFSGETFEEIIDCSGKCILPGLVDAHTH 89
          +DG IK IG   ++          + I+ +GK ++PG +D HTH
Sbjct: 38 EDGLIKQIGDNLIVPGGV------KTIEANGKMVIPGGIDVHTH 75


>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
          Length = 456

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 15/51 (29%), Positives = 22/51 (43%)

Query: 337 PNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGK 387
           PN +C S   + HL C     S+P      T  +    G ++ HG L V +
Sbjct: 81  PNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAE 131


>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
          Length = 457

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 15/51 (29%), Positives = 22/51 (43%)

Query: 337 PNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGK 387
           PN +C S   + HL C     S+P      T  +    G ++ HG L V +
Sbjct: 81  PNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAE 131


>gi|38257139 protein kinase, cAMP-dependent, regulatory, type I,
           beta [Homo sapiens]
          Length = 381

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 4/53 (7%)

Query: 23  ERFLARDALRSLAVLEGASLVV----GKDGFIKAIGPADVIQRQFSGETFEEI 71
           ER    DAL  +   +G  +VV    G D +I   G A V+QR+   E + E+
Sbjct: 263 ERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEV 315


>gi|31742505 Rho family guanine-nucleotide exchange factor [Homo
           sapiens]
          Length = 1114

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 2/40 (5%)

Query: 205 DDIINNHLPKLKELGRNGEIH--VDNIDVFCEKGVFDLDS 242
           DD IN +  K   LG++ E H  +D +  +CE G++ L S
Sbjct: 410 DDFINGNKKKWDILGKSLEFHRQLDKVSQWCEAGIYLLAS 449


>gi|238908495 similar to pleckstrin homology domain protein (5V327)
           [Homo sapiens]
          Length = 506

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 2/123 (1%)

Query: 124 ERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARRELDIG 183
           ER+R   EE  F S Q   Q +  +   L   K     +L+ E+K+   +ER  RE +  
Sbjct: 314 ERSRALEEEREFYSSQS--QALQNSLQELTAEKQQAERELKAEVKVRMDLERRLREAEGA 371

Query: 184 ISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDLDST 243
           + +   G +S  + K   E     +++     +E  RN E+      +          +T
Sbjct: 372 LRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAAT 431

Query: 244 RRI 246
           RRI
Sbjct: 432 RRI 434


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,080,786
Number of Sequences: 37866
Number of extensions: 639966
Number of successful extensions: 1336
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1327
Number of HSP's gapped (non-prelim): 17
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.