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Search of human proteins with 223890153
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890153 DSN1, MIND kinetochore complex component, homolog
isoform 3 [Homo sapiens]
(340 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890153 DSN1, MIND kinetochore complex component, homolog i... 668 0.0
gi|223890149 DSN1, MIND kinetochore complex component, homolog i... 668 0.0
gi|223890147 DSN1, MIND kinetochore complex component, homolog i... 668 0.0
gi|223972618 DSN1, MIND kinetochore complex component, homolog i... 668 0.0
gi|223890151 DSN1, MIND kinetochore complex component, homolog i... 467 e-132
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.003
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 37 0.019
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 37 0.019
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 37 0.025
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 37 0.025
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 37 0.033
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 35 0.074
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 35 0.096
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 35 0.096
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 35 0.096
gi|94967023 disabled homolog 2 interacting protein isoform 1 [Ho... 35 0.13
gi|71061468 centromere protein E [Homo sapiens] 35 0.13
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 34 0.16
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 34 0.16
gi|56119108 schlafen family member 13 [Homo sapiens] 33 0.28
gi|206597549 coiled-coil domain containing 36 [Homo sapiens] 33 0.37
gi|206597547 coiled-coil domain containing 36 [Homo sapiens] 33 0.37
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 33 0.37
gi|219803769 trichoplein [Homo sapiens] 33 0.37
gi|14150056 trichoplein [Homo sapiens] 33 0.37
gi|55770834 centromere protein F [Homo sapiens] 33 0.37
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 33 0.48
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 32 0.62
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 32 0.82
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 32 0.82
>gi|223890153 DSN1, MIND kinetochore complex component, homolog
isoform 3 [Homo sapiens]
Length = 340
Score = 668 bits (1724), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 60
MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK
Sbjct: 1 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 60
Query: 61 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 120
SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC
Sbjct: 61 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 120
Query: 121 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 180
LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN
Sbjct: 121 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 180
Query: 181 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP
Sbjct: 181 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
Query: 241 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 300
MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV
Sbjct: 241 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 300
Query: 301 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 301 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
>gi|223890149 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 668 bits (1724), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 60
MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK
Sbjct: 17 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 76
Query: 61 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 120
SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC
Sbjct: 77 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 136
Query: 121 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 180
LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN
Sbjct: 137 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 196
Query: 181 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP
Sbjct: 197 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 256
Query: 241 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 300
MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV
Sbjct: 257 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 316
Query: 301 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 317 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 356
>gi|223890147 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 668 bits (1724), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 60
MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK
Sbjct: 17 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 76
Query: 61 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 120
SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC
Sbjct: 77 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 136
Query: 121 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 180
LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN
Sbjct: 137 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 196
Query: 181 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP
Sbjct: 197 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 256
Query: 241 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 300
MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV
Sbjct: 257 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 316
Query: 301 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 317 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 356
>gi|223972618 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 668 bits (1724), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 60
MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK
Sbjct: 17 MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSK 76
Query: 61 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 120
SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC
Sbjct: 77 SLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGC 136
Query: 121 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 180
LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN
Sbjct: 137 LLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSN 196
Query: 181 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP
Sbjct: 197 GKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 256
Query: 241 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 300
MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV
Sbjct: 257 MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKV 316
Query: 301 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 317 SVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 356
>gi|223890151 DSN1, MIND kinetochore complex component, homolog
isoform 2 [Homo sapiens]
Length = 249
Score = 467 bits (1201), Expect = e-132
Identities = 239/240 (99%), Positives = 239/240 (99%)
Query: 101 ITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 160
I ELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK
Sbjct: 10 IDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 69
Query: 161 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 220
HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA
Sbjct: 70 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 129
Query: 221 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 280
KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ
Sbjct: 130 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 189
Query: 281 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 190 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 249
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 40.0 bits (92), Expect = 0.003
Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 24/252 (9%)
Query: 48 NCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRS 107
+C++ L+++ L Q + R + W RAS +++ K + +H I +L
Sbjct: 1312 HCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQS--EKEMEELHHNIDDL--- 1366
Query: 108 ISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLE 167
L E K L C + ++QK + +D ++ES + + + LKH D ++
Sbjct: 1367 ----LQEKKSLEC-EVEELHRTVQKRQQ-QKDFIDGNVESLMTEL-EIEKSLKHHEDIVD 1419
Query: 168 TDGTLQKCF--EDSNGKASDFSLEASVAEMK--EYITKFSLERQTWDQLLLHYQQEAKEI 223
++K S + +D L + +E+ + TK ++E+ T + L + E
Sbjct: 1420 EIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEE 1479
Query: 224 LSRGSTEAKITEVKV-EPMTYLGSSQNEVLNTKPDYQKILQNQSKV-------FDCMELV 275
L R + E + VK + + L + ++ K ++IL+ +K+ F C+
Sbjct: 1480 LERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKK 1539
Query: 276 MDELQGSVKQLQ 287
++L +++LQ
Sbjct: 1540 KEKLTEELQKLQ 1551
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 37.4 bits (85), Expect = 0.019
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 23/134 (17%)
Query: 190 ASVAEMKEYITKFSLERQT-WDQLLLHYQQEAKEI------LSRGSTEAKITE------- 235
A++ + E I + + ERQT + LL H+Q+ KE+ L RG +A E
Sbjct: 1637 AALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADR 1696
Query: 236 VKVE-PMTYLGSSQNEVLNTKPDYQKILQNQSKVFD--------CMELVMDELQGSVKQL 286
VKVE + + + QNEV++ Y K+LQ + +F M+L +++L + L
Sbjct: 1697 VKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDL 1756
Query: 287 QAFMDESTQCFQKV 300
+++ Q V
Sbjct: 1757 PQIINKRINFLQSV 1770
Score = 33.1 bits (74), Expect = 0.37
Identities = 46/204 (22%), Positives = 85/204 (41%), Gaps = 19/204 (9%)
Query: 80 WRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLR- 138
W ++ +E +R + T+ S +L +S+ +G LS ++ L P ++
Sbjct: 2862 WLHSAKEELHRWSDMSG-DSSATQKKLSKIKELIDSREIGASRLSR----VESLAPEVKQ 2916
Query: 139 DTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFED--SNGKASDFSLEASVAEMK 196
+T E + +L + K + D + Q C E+ S S+ VA+++
Sbjct: 2917 NTTASGCELMHTEMQALRADWKQWEDSVFQT---QSCLENLVSQMALSEQEFSGQVAQLE 2973
Query: 197 EYITKFSLERQTWDQ--LLLHYQQEAKEILSRGSTEAKITEV--KVEPMTY-LGSSQNEV 251
+ + +FS +TW Q LL + +EI+ +I + K EP T L S NE+
Sbjct: 2974 QALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNEL 3033
Query: 252 LNTKPD---YQKILQNQSKVFDCM 272
D Y + K ++C+
Sbjct: 3034 CRFSRDLSTYSGKVSGLIKEYNCL 3057
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 37.4 bits (85), Expect = 0.019
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 23/134 (17%)
Query: 190 ASVAEMKEYITKFSLERQT-WDQLLLHYQQEAKEI------LSRGSTEAKITE------- 235
A++ + E I + + ERQT + LL H+Q+ KE+ L RG +A E
Sbjct: 1630 AALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADR 1689
Query: 236 VKVE-PMTYLGSSQNEVLNTKPDYQKILQNQSKVFD--------CMELVMDELQGSVKQL 286
VKVE + + + QNEV++ Y K+LQ + +F M+L +++L + L
Sbjct: 1690 VKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDL 1749
Query: 287 QAFMDESTQCFQKV 300
+++ Q V
Sbjct: 1750 PQIINKRINFLQSV 1763
Score = 33.1 bits (74), Expect = 0.37
Identities = 46/204 (22%), Positives = 85/204 (41%), Gaps = 19/204 (9%)
Query: 80 WRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLR- 138
W ++ +E +R + T+ S +L +S+ +G LS ++ L P ++
Sbjct: 2855 WLHSAKEELHRWSDMSG-DSSATQKKLSKIKELIDSREIGASRLSR----VESLAPEVKQ 2909
Query: 139 DTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFED--SNGKASDFSLEASVAEMK 196
+T E + +L + K + D + Q C E+ S S+ VA+++
Sbjct: 2910 NTTASGCELMHTEMQALRADWKQWEDSVFQT---QSCLENLVSQMALSEQEFSGQVAQLE 2966
Query: 197 EYITKFSLERQTWDQ--LLLHYQQEAKEILSRGSTEAKITEV--KVEPMTY-LGSSQNEV 251
+ + +FS +TW Q LL + +EI+ +I + K EP T L S NE+
Sbjct: 2967 QALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNEL 3026
Query: 252 LNTKPD---YQKILQNQSKVFDCM 272
D Y + K ++C+
Sbjct: 3027 CRFSRDLSTYSGKVSGLIKEYNCL 3050
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 37.0 bits (84), Expect = 0.025
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 31/252 (12%)
Query: 70 SASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFS 129
S Y D +R A E R Q + + +++ +LA+SK L Q
Sbjct: 540 SQQYMDLENEFRIALTVEARR-------FQDVKDGFENVATELAKSKHA----LIWAQRK 588
Query: 130 IQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETD-GTLQKCFEDSNGKASDFSL 188
+ ++D E + K + +S+ + A L+ TL+ ED K+ L
Sbjct: 589 ENESSSLIKDLTCMVKEQ-KTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIEL 647
Query: 189 --EASVAEMKEYITKFSL------ERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
V + E K SL ER+ W L QQ + +RG EA+I + E
Sbjct: 648 LKHEKVQLISELAAKESLIFGLRTERKVWGHELA--QQGSSLAQNRGKLEAQIESLSREN 705
Query: 241 --MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQ 298
+ S ++ L K KI+ +Q++ ++ + E +K+LQ + E +C Q
Sbjct: 706 ECLRKTNESDSDALRIKC---KIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQ 762
Query: 299 KVSVQLGKRSMQ 310
+ QL ++S Q
Sbjct: 763 E---QLDEKSSQ 771
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 37.0 bits (84), Expect = 0.025
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 31/252 (12%)
Query: 70 SASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFS 129
S Y D +R A E R Q + + +++ +LA+SK L Q
Sbjct: 633 SQQYMDLENEFRIALTVEARR-------FQDVKDGFENVATELAKSKHA----LIWAQRK 681
Query: 130 IQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETD-GTLQKCFEDSNGKASDFSL 188
+ ++D E + K + +S+ + A L+ TL+ ED K+ L
Sbjct: 682 ENESSSLIKDLTCMVKEQ-KTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIEL 740
Query: 189 --EASVAEMKEYITKFSL------ERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP 240
V + E K SL ER+ W L QQ + +RG EA+I + E
Sbjct: 741 LKHEKVQLISELAAKESLIFGLRTERKVWGHELA--QQGSSLAQNRGKLEAQIESLSREN 798
Query: 241 --MTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQ 298
+ S ++ L K KI+ +Q++ ++ + E +K+LQ + E +C Q
Sbjct: 799 ECLRKTNESDSDALRIKC---KIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQ 855
Query: 299 KVSVQLGKRSMQ 310
+ QL ++S Q
Sbjct: 856 E---QLDEKSSQ 864
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 36.6 bits (83), Expect = 0.033
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 188 LEASVAEMKEYITKFSLERQTWDQLLLHYQ---QEAKEILSRGSTEAKITEVKVEPMTYL 244
L S +++EY T F + +T +L+L YQ +E +E L R + I + ++ L
Sbjct: 925 LRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGI--ISRL 982
Query: 245 GSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQ 303
S + E+ + Q + ++ K+ D E + L + +L M TQ ++ S+Q
Sbjct: 983 MSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARL---MSALTQLKERYSMQ 1038
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 35.4 bits (80), Expect = 0.074
Identities = 35/184 (19%), Positives = 74/184 (40%), Gaps = 26/184 (14%)
Query: 138 RDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKE 197
+D+ SL+ R + +L + K DG+E T K DS+ K + E++E
Sbjct: 775 KDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRF-LRRQELRE 833
Query: 198 YITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPD 257
E++ QL QQ+ ++I R + E+++ K
Sbjct: 834 LRFLQKEEQRAQQQLNSKLQQQREQIFRR--------------------FEQEMMSKKRQ 873
Query: 258 YQKILQN----QSKVFDCMELV-MDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQL 312
Y + ++N Q + + +E + L+ K+++ ++ FQ + K + ++
Sbjct: 874 YDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEV 933
Query: 313 DPSP 316
+ +P
Sbjct: 934 EKAP 937
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 35.0 bits (79), Expect = 0.096
Identities = 52/230 (22%), Positives = 96/230 (41%), Gaps = 18/230 (7%)
Query: 90 RRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKL-EPFLRDTKGFSLESF 148
R K + ++Q + R + E ++L LL +Q + E L+ K S E+
Sbjct: 171 RDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETT 230
Query: 149 RAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQT 208
+ S L + ++ K ++ K ++ S E A+ E K Q
Sbjct: 231 ITQQSVSDSHLAELQEKIQQTEATNKILQE---KLNEMSYELKCAQ--ESSQKQDGTIQN 285
Query: 209 WDQLLLHYQQEAKEILS----RGSTEAKITEVKVEP-MTYLGSSQNEVLNTKPDYQKI-- 261
+ L ++E +E+ + T AK+ E+ + + L SS+ T P Q++
Sbjct: 286 LKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEG----TSPAQQQVAL 341
Query: 262 LQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 311
L QS +F C +L + +LQ V+Q + + ++ QC Q V + Q+
Sbjct: 342 LDLQSALF-CSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQK 390
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 35.0 bits (79), Expect = 0.096
Identities = 52/230 (22%), Positives = 96/230 (41%), Gaps = 18/230 (7%)
Query: 90 RRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKL-EPFLRDTKGFSLESF 148
R K + ++Q + R + E ++L LL +Q + E L+ K S E+
Sbjct: 171 RDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETT 230
Query: 149 RAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQT 208
+ S L + ++ K ++ K ++ S E A+ E K Q
Sbjct: 231 ITQQSVSDSHLAELQEKIQQTEATNKILQE---KLNEMSYELKCAQ--ESSQKQDGTIQN 285
Query: 209 WDQLLLHYQQEAKEILS----RGSTEAKITEVKVEP-MTYLGSSQNEVLNTKPDYQKI-- 261
+ L ++E +E+ + T AK+ E+ + + L SS+ T P Q++
Sbjct: 286 LKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEG----TSPAQQQVAL 341
Query: 262 LQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 311
L QS +F C +L + +LQ V+Q + + ++ QC Q V + Q+
Sbjct: 342 LDLQSALF-CSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQK 390
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 35.0 bits (79), Expect = 0.096
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 12/160 (7%)
Query: 172 LQKCFEDSNGKASD-FSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTE 230
L K E +G + D S + KE +TK ER DQLL + + + +
Sbjct: 130 LTKLVEQGSGLSMDQHSNIRDLLRFKEEVTK---ER---DQLLSEVVKLRESLAQTTEQQ 183
Query: 231 AKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELV---MDELQGSVKQLQ 287
+ K E + Q E+ + + + + + K+ ++ + MD Q +K LQ
Sbjct: 184 QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQ 243
Query: 288 AFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQN 327
++ +S + QK+ QL ++ + L+ A++L + Q++N
Sbjct: 244 QYVQKSKEELQKLEQQLKEQKI--LNERAAKELEQFQMRN 281
>gi|94967023 disabled homolog 2 interacting protein isoform 1 [Homo
sapiens]
Length = 1132
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 188 LEASVAEMKEYITKFSLERQTWDQLLLHYQ---QEAKEILSRGSTEAKITEVKVEPMTYL 244
L S +++EY T F + +T +L+L YQ +E +E L R + I + ++ L
Sbjct: 1021 LRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGI--ISRL 1078
Query: 245 GSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDE 292
S + E+ + Q + ++ K+ D E + L + +L + + +
Sbjct: 1079 MSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQ 1126
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 34.7 bits (78), Expect = 0.13
Identities = 50/259 (19%), Positives = 105/259 (40%), Gaps = 36/259 (13%)
Query: 26 LEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASM 85
LE N+ +++E ++L +K + + + L K+ L QE++ Q+R +
Sbjct: 837 LEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQEL--QEKTREVQERLNEMEQLKE 894
Query: 86 KETNRRKSLHPIHQGITELSRSISVDLAESKRLG------CLLLSSFQFSIQKLEPFLRD 139
+ NR +L + + T ++ + L E K L L S Q +L+ + D
Sbjct: 895 QLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHD 954
Query: 140 TKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYI 199
T ++++ ++L +H ET TL+ + S + + +E + E K+
Sbjct: 955 TVNMNIDTQEQLRNALESLKQH----QETINTLKS--KISEEVSRNLHMEENTGETKD-- 1006
Query: 200 TKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ 259
+QQ+ I + EAK T+ + NE++ +
Sbjct: 1007 ---------------EFQQKMVGIDKKQDLEAKNTQTLTADV-----KDNEIIEQQRKIF 1046
Query: 260 KILQNQSKVFDCMELVMDE 278
++Q ++++ +E V+ E
Sbjct: 1047 SLIQEKNELQQMLESVIAE 1065
>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 34.3 bits (77), Expect = 0.16
Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 23/154 (14%)
Query: 187 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA---KEILSRGSTEAKITEVKVEPMTY 243
SL+ ++ + KF QL+ + E KE L + + + TE +V+
Sbjct: 135 SLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVK---- 190
Query: 244 LGSSQNEVLNTKPDYQKILQ-----------NQSKVFDCMELVMDELQGSVKQLQAFMDE 292
+++E+ TK QK+ + + +K EL +D+ + +K+L ++
Sbjct: 191 --DTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLEL 248
Query: 293 STQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQ 326
ST FQ+ + KR+ + D + K+L+ ++Q
Sbjct: 249 STNSFQRQLLAERKRAYEAHDEN---KVLQKEVQ 279
>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 34.3 bits (77), Expect = 0.16
Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 23/154 (14%)
Query: 187 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA---KEILSRGSTEAKITEVKVEPMTY 243
SL+ ++ + KF QL+ + E KE L + + + TE +V+
Sbjct: 135 SLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVK---- 190
Query: 244 LGSSQNEVLNTKPDYQKILQ-----------NQSKVFDCMELVMDELQGSVKQLQAFMDE 292
+++E+ TK QK+ + + +K EL +D+ + +K+L ++
Sbjct: 191 --DTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLEL 248
Query: 293 STQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQ 326
ST FQ+ + KR+ + D + K+L+ ++Q
Sbjct: 249 STNSFQRQLLAERKRAYEAHDEN---KVLQKEVQ 279
>gi|56119108 schlafen family member 13 [Homo sapiens]
Length = 897
Score = 33.5 bits (75), Expect = 0.28
Identities = 65/269 (24%), Positives = 109/269 (40%), Gaps = 39/269 (14%)
Query: 34 EERIHLGSSP--------KKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASM 85
E ++ L SP KKG L H+ LQ HL P W+ S+
Sbjct: 366 ESQLSLSDSPSLCRPVYSKKG----LEHKADLQQ---HLFPVPPGHLECTPESLWKELSL 418
Query: 86 KETNRRKSLH----PIHQGITELSRSISVDLAESKRLG--CLLLSSFQFSIQKLEPFLRD 139
+ ++ +H P QGI LSRS +VDL ++ G C L Q S L LR+
Sbjct: 419 QHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
Query: 140 TKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYI 199
+ A +L ++L + G ++ + ++S +LEA+V+ M +Y
Sbjct: 479 QDAEGQDYCTRTAFTLKQKLVNMG-GYTGKVCVRAKVLCLSPESSAEALEAAVSPM-DYP 536
Query: 200 TKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ 259
+SL + LL ++ I+ G ++ E + L + Q E+ + +
Sbjct: 537 ASYSLAGTQHMEALL----QSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFS-----R 587
Query: 260 KILQNQSKVFDCMELVMDELQGSVKQLQA 288
+ +N+ EL + L GS K + A
Sbjct: 588 SLRKNR-------ELFVHGLPGSGKTIMA 609
>gi|206597549 coiled-coil domain containing 36 [Homo sapiens]
Length = 594
Score = 33.1 bits (74), Expect = 0.37
Identities = 36/167 (21%), Positives = 77/167 (46%), Gaps = 16/167 (9%)
Query: 167 ETDGTLQKCFEDSNGKASDF----SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKE 222
++ G L++ FE+ +A D +L V+ ++E I + + + H ++
Sbjct: 111 KSKGLLEQ-FEEKKKRAKDKCDSETLYNFVSNVRESILRLQTSVEKSED---HLSSRSQS 166
Query: 223 ILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGS 282
IL T AK + ++ L E + K + ++ + K F+ + E++ +
Sbjct: 167 ILDSLETVAKTLQETIQAQNDLVF---EAVQDKGNMEQAILEMKKRFEARQGEFIEMKSN 223
Query: 283 VKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPP 329
+K L+ + + +Q FQ++ QLG+ ++ PS +L +L + PP
Sbjct: 224 LKHLEVLVAQQSQEFQQLCEQLGQLNV----PSVLAELKRL-ISVPP 265
>gi|206597547 coiled-coil domain containing 36 [Homo sapiens]
Length = 594
Score = 33.1 bits (74), Expect = 0.37
Identities = 36/167 (21%), Positives = 77/167 (46%), Gaps = 16/167 (9%)
Query: 167 ETDGTLQKCFEDSNGKASDF----SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKE 222
++ G L++ FE+ +A D +L V+ ++E I + + + H ++
Sbjct: 111 KSKGLLEQ-FEEKKKRAKDKCDSETLYNFVSNVRESILRLQTSVEKSED---HLSSRSQS 166
Query: 223 ILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGS 282
IL T AK + ++ L E + K + ++ + K F+ + E++ +
Sbjct: 167 ILDSLETVAKTLQETIQAQNDLVF---EAVQDKGNMEQAILEMKKRFEARQGEFIEMKSN 223
Query: 283 VKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPP 329
+K L+ + + +Q FQ++ QLG+ ++ PS +L +L + PP
Sbjct: 224 LKHLEVLVAQQSQEFQQLCEQLGQLNV----PSVLAELKRL-ISVPP 265
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 33.1 bits (74), Expect = 0.37
Identities = 31/132 (23%), Positives = 62/132 (46%), Gaps = 25/132 (18%)
Query: 210 DQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVF 269
++L ++E+K+ +S ++++ +V + MT L Q V + + + + + N K+
Sbjct: 327 NELRAELKEESKKAVS---LKSQLEDVSILQMT-LKEFQERVEDLEKERKLLNDNYDKLL 382
Query: 270 DCM--------------ELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPS 315
+ M EL+ ++LQ V QLQ +D + +KV ++L + Q D
Sbjct: 383 ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNED-- 440
Query: 316 PARKLLKLQLQN 327
LKL++ N
Sbjct: 441 -----LKLEVTN 447
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 33.1 bits (74), Expect = 0.37
Identities = 53/259 (20%), Positives = 107/259 (41%), Gaps = 16/259 (6%)
Query: 72 SYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQ 131
SYQ +++R MKE +R+SL + + +L + E + L L + S+
Sbjct: 59 SYQRSMHAYQREKMKE-EKRRSLEARREKLRQL-------MQEEQDLLARELEELRLSMN 110
Query: 132 KLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEAS 191
E +R+ G L+S + + L E + + + L++ D + K S E
Sbjct: 111 LQERRIREQHG-KLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQ 169
Query: 192 VAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEV 251
E K+ E + ++ Y++ +E L R E + +++ + Q E
Sbjct: 170 KEEKKQQEATAEQENKRYEN---EYERARREALERMKAEEERRQLEDKLQAEALLQQMEE 226
Query: 252 LNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQ---CFQKVSVQLGKRS 308
L K L+ + + ++ L+ KQ++AF ++ + + QL +R+
Sbjct: 227 LKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRT 286
Query: 309 MQ-QLDPSPARKLLKLQLQ 326
Q Q + R++L+ L+
Sbjct: 287 QQIQEELEADRRILQALLE 305
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 33.1 bits (74), Expect = 0.37
Identities = 53/259 (20%), Positives = 107/259 (41%), Gaps = 16/259 (6%)
Query: 72 SYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQ 131
SYQ +++R MKE +R+SL + + +L + E + L L + S+
Sbjct: 59 SYQRSMHAYQREKMKE-EKRRSLEARREKLRQL-------MQEEQDLLARELEELRLSMN 110
Query: 132 KLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEAS 191
E +R+ G L+S + + L E + + + L++ D + K S E
Sbjct: 111 LQERRIREQHG-KLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQ 169
Query: 192 VAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEV 251
E K+ E + ++ Y++ +E L R E + +++ + Q E
Sbjct: 170 KEEKKQQEATAEQENKRYEN---EYERARREALERMKAEEERRQLEDKLQAEALLQQMEE 226
Query: 252 LNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQ---CFQKVSVQLGKRS 308
L K L+ + + ++ L+ KQ++AF ++ + + QL +R+
Sbjct: 227 LKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRT 286
Query: 309 MQ-QLDPSPARKLLKLQLQ 326
Q Q + R++L+ L+
Sbjct: 287 QQIQEELEADRRILQALLE 305
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 33.1 bits (74), Expect = 0.37
Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 34/249 (13%)
Query: 50 DLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSIS 109
+LS ++ + L L +E +S + + +++ + +KSL +H+ E +
Sbjct: 2638 ELSGEKNRLAGELQLLLEEIKSS----KDQLKELTLENSELKKSLDCMHKDQVEKEGKVR 2693
Query: 110 VDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKG---FSLESFRAKASSLSEELKHFADGL 166
++AE + L L + +K + L DT ++++R K +S E L + L
Sbjct: 2694 EEIAEYQ----LRLHEAE---KKHQALLLDTNKQYEVEIQTYREKLTSKEECLS--SQKL 2744
Query: 167 ETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSR 226
E D L+ E+ N SL+A+ ++E L++ D L Y + K+ R
Sbjct: 2745 EID-LLKSSKEELNN-----SLKATTQILEE------LKKTKMDNL--KYVNQLKKENER 2790
Query: 227 GSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQL 286
+ K+ + + + E+L + + Q + K M+ +DEL +K+L
Sbjct: 2791 AQGKMKLLIKSCKQL----EEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKEL 2846
Query: 287 QAFMDESTQ 295
+ ++E T+
Sbjct: 2847 KETLEEKTK 2855
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 32.7 bits (73), Expect = 0.48
Identities = 52/284 (18%), Positives = 109/284 (38%), Gaps = 33/284 (11%)
Query: 54 QERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLA 113
+ RL + L +EQ + + S A ++ET + K+ + L + ++
Sbjct: 824 ENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAEL 883
Query: 114 ESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGL-ETDGTL 172
E+ + +++ QK+ L+D + F + E++K A + + L
Sbjct: 884 ETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEEKL 943
Query: 173 QKCFEDSNGKASDFSLEASVAEMKEY----------------ITKFSLERQTWDQLLLHY 216
QK + +E +A +K+ +T+ S + ++ L+
Sbjct: 944 QKVTQHHK------KIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDL 997
Query: 217 QQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ-----KILQNQSKVFDC 271
KEILS+ K+ + E + + + E LN K + ++Q QSK
Sbjct: 998 LAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGE-LNEKQKMELEQNVVLVQQQSKELSV 1056
Query: 272 MELVMDELQGSV----KQLQAFMDESTQCFQKVSVQLGKRSMQQ 311
++ M ++ V ++L+A + +K +QL Q+
Sbjct: 1057 LKEKMAQMSSLVEKKDRELKALEEALRASQEKHRLQLNTEKEQK 1100
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 32.3 bits (72), Expect = 0.62
Identities = 47/194 (24%), Positives = 69/194 (35%), Gaps = 20/194 (10%)
Query: 58 QSKSLHLSPQEQSASYQDRRQSWRRASM---------KETNRRKSLHPIHQGITELSRSI 108
+S L +S Q Q ++Q RR S+ + RR S P H G + +
Sbjct: 44 RSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDH-- 101
Query: 109 SVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEEL---KHFADG 165
D ESKR +S F Q++ + E RA A + + KH A
Sbjct: 102 --DSLESKRPRLEQVSDSHF--QRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPS 157
Query: 166 LETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILS 225
G Q C +D N S S E + M + + Q +L QQ +E
Sbjct: 158 SPISG--QPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAK 215
Query: 226 RGSTEAKITEVKVE 239
E ++ VE
Sbjct: 216 PPEPEKPVSPPPVE 229
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 32.0 bits (71), Expect = 0.82
Identities = 36/171 (21%), Positives = 76/171 (44%), Gaps = 21/171 (12%)
Query: 146 ESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLE 205
ES R + ++EL+ E +G ++ F K++ +LEA +A+++E + + + E
Sbjct: 1791 ESARQQLERQNKELRSKLH--EMEGAVKSKF-----KSTIAALEAKIAQLEEQVEQEARE 1843
Query: 206 RQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQ 265
+Q + L ++ KEIL + E K+ E E Q E N + ++
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE--------QAEKGNAR------VKQL 1889
Query: 266 SKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSP 316
+ + E + + ++LQ +DE+T+ + + ++ + P P
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPP 1940
Score = 31.2 bits (69), Expect = 1.4
Identities = 54/273 (19%), Positives = 106/273 (38%), Gaps = 23/273 (8%)
Query: 54 QERLQSKSLHLSPQ--EQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELS---RSI 108
++R Q + +L+ Q E++A+Y ++ R + + L Q ++ L R
Sbjct: 1401 KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460
Query: 109 SVDLAESKRLGCLLLSSFQFSIQKLEPFLRD--TKGFSLESFRAKASSLSEELKHFADGL 166
LAE K + S + + E R+ TK SL +A EEL+ L
Sbjct: 1461 DQLLAEEKNIS----SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1516
Query: 167 ETDGTLQKCFEDSNGK------ASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 220
+ + +D GK S +LE + EMK + + E Q + L +
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1576
Query: 221 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 280
+ + + + + + + E + ++ +Y+ L+++ K +L+
Sbjct: 1577 QALKGQFERDLQARDEQNE------EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 281 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLD 313
G +K L+ D + + ++ QL K Q D
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKD 1663
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 32.0 bits (71), Expect = 0.82
Identities = 36/171 (21%), Positives = 76/171 (44%), Gaps = 21/171 (12%)
Query: 146 ESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLE 205
ES R + ++EL+ E +G ++ F K++ +LEA +A+++E + + + E
Sbjct: 1784 ESARQQLERQNKELRSKLH--EMEGAVKSKF-----KSTIAALEAKIAQLEEQVEQEARE 1836
Query: 206 RQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQ 265
+Q + L ++ KEIL + E K+ E E Q E N + ++
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE--------QAEKGNAR------VKQL 1882
Query: 266 SKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSP 316
+ + E + + ++LQ +DE+T+ + + ++ + P P
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPP 1933
Score = 31.2 bits (69), Expect = 1.4
Identities = 54/273 (19%), Positives = 106/273 (38%), Gaps = 23/273 (8%)
Query: 54 QERLQSKSLHLSPQ--EQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELS---RSI 108
++R Q + +L+ Q E++A+Y ++ R + + L Q ++ L R
Sbjct: 1394 KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
Query: 109 SVDLAESKRLGCLLLSSFQFSIQKLEPFLRD--TKGFSLESFRAKASSLSEELKHFADGL 166
LAE K + S + + E R+ TK SL +A EEL+ L
Sbjct: 1454 DQLLAEEKNIS----SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
Query: 167 ETDGTLQKCFEDSNGK------ASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 220
+ + +D GK S +LE + EMK + + E Q + L +
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 221 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 280
+ + + + + + + E + ++ +Y+ L+++ K +L+
Sbjct: 1570 QALKGQFERDLQARDEQNE------EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 281 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLD 313
G +K L+ D + + ++ QL K Q D
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKD 1656
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,837,343
Number of Sequences: 37866
Number of extensions: 483409
Number of successful extensions: 2126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 2057
Number of HSP's gapped (non-prelim): 146
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.