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Search of human proteins with 223890151
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890151 DSN1, MIND kinetochore complex component, homolog
isoform 2 [Homo sapiens]
(249 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890151 DSN1, MIND kinetochore complex component, homolog i... 485 e-137
gi|223890153 DSN1, MIND kinetochore complex component, homolog i... 467 e-132
gi|223890149 DSN1, MIND kinetochore complex component, homolog i... 467 e-132
gi|223890147 DSN1, MIND kinetochore complex component, homolog i... 467 e-132
gi|223972618 DSN1, MIND kinetochore complex component, homolog i... 467 e-132
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 37 0.012
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 37 0.012
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 37 0.021
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 35 0.047
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 35 0.061
gi|94967023 disabled homolog 2 interacting protein isoform 1 [Ho... 35 0.080
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 35 0.080
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 35 0.080
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 34 0.10
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 34 0.10
gi|206597549 coiled-coil domain containing 36 [Homo sapiens] 33 0.23
gi|206597547 coiled-coil domain containing 36 [Homo sapiens] 33 0.23
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 33 0.23
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 33 0.30
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 33 0.30
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 32 0.52
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 32 0.52
gi|4759198 homer 1 [Homo sapiens] 32 0.52
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 32 0.67
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 32 0.67
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 32 0.67
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 32 0.67
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [... 31 1.2
gi|4758104 cytochrome P450, family 7, subfamily B, polypeptide 1... 30 1.5
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 30 1.5
>gi|223890151 DSN1, MIND kinetochore complex component, homolog
isoform 2 [Homo sapiens]
Length = 249
Score = 485 bits (1249), Expect = e-137
Identities = 249/249 (100%), Positives = 249/249 (100%)
Query: 1 MTSVTRSEIIDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAK 60
MTSVTRSEIIDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAK
Sbjct: 1 MTSVTRSEIIDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAK 60
Query: 61 ASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQ 120
ASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQ
Sbjct: 61 ASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQ 120
Query: 121 LLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDC 180
LLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDC
Sbjct: 121 LLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDC 180
Query: 181 MELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAI 240
MELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAI
Sbjct: 181 MELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAI 240
Query: 241 HGSGSGSCQ 249
HGSGSGSCQ
Sbjct: 241 HGSGSGSCQ 249
>gi|223890153 DSN1, MIND kinetochore complex component, homolog
isoform 3 [Homo sapiens]
Length = 340
Score = 467 bits (1201), Expect = e-132
Identities = 239/240 (99%), Positives = 239/240 (99%)
Query: 10 IDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 69
I ELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK
Sbjct: 101 ITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 160
Query: 70 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 129
HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA
Sbjct: 161 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 220
Query: 130 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 189
KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ
Sbjct: 221 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 280
Query: 190 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 249
GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 281 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 340
>gi|223890149 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 467 bits (1201), Expect = e-132
Identities = 239/240 (99%), Positives = 239/240 (99%)
Query: 10 IDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 69
I ELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK
Sbjct: 117 ITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 176
Query: 70 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 129
HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA
Sbjct: 177 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 236
Query: 130 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 189
KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ
Sbjct: 237 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 296
Query: 190 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 249
GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 297 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 356
>gi|223890147 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 467 bits (1201), Expect = e-132
Identities = 239/240 (99%), Positives = 239/240 (99%)
Query: 10 IDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 69
I ELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK
Sbjct: 117 ITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 176
Query: 70 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 129
HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA
Sbjct: 177 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 236
Query: 130 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 189
KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ
Sbjct: 237 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 296
Query: 190 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 249
GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 297 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 356
>gi|223972618 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 467 bits (1201), Expect = e-132
Identities = 239/240 (99%), Positives = 239/240 (99%)
Query: 10 IDELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 69
I ELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK
Sbjct: 117 ITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELK 176
Query: 70 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 129
HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA
Sbjct: 177 HFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA 236
Query: 130 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 189
KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ
Sbjct: 237 KEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQ 296
Query: 190 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 249
GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Sbjct: 297 GSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ 356
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 37.4 bits (85), Expect = 0.012
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 23/134 (17%)
Query: 99 ASVAEMKEYITKFSLERQT-WDQLLLHYQQEAKEI------LSRGSTEAKITE------- 144
A++ + E I + + ERQT + LL H+Q+ KE+ L RG +A E
Sbjct: 1637 AALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADR 1696
Query: 145 VKVE-PMTYLGSSQNEVLNTKPDYQKILQNQSKVFD--------CMELVMDELQGSVKQL 195
VKVE + + + QNEV++ Y K+LQ + +F M+L +++L + L
Sbjct: 1697 VKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDL 1756
Query: 196 QAFMDESTQCFQKV 209
+++ Q V
Sbjct: 1757 PQIINKRINFLQSV 1770
Score = 32.0 bits (71), Expect = 0.52
Identities = 41/173 (23%), Positives = 74/173 (42%), Gaps = 18/173 (10%)
Query: 20 DLAESKRLGCLLLSSFQFSIQKLEPFLR-DTKGFSLESFRAKASSLSEELKHFADGLETD 78
+L +S+ +G LS ++ L P ++ +T E + +L + K + D +
Sbjct: 2892 ELIDSREIGASRLSR----VESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQT 2947
Query: 79 GTLQKCFED--SNGKASDFSLEASVAEMKEYITKFSLERQTWDQ--LLLHYQQEAKEILS 134
Q C E+ S S+ VA++++ + +FS +TW Q LL + +EI+
Sbjct: 2948 ---QSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVE 3004
Query: 135 RGSTEAKITEV--KVEPMTY-LGSSQNEVLNTKPD---YQKILQNQSKVFDCM 181
+I + K EP T L S NE+ D Y + K ++C+
Sbjct: 3005 CWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCL 3057
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 37.4 bits (85), Expect = 0.012
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 23/134 (17%)
Query: 99 ASVAEMKEYITKFSLERQT-WDQLLLHYQQEAKEI------LSRGSTEAKITE------- 144
A++ + E I + + ERQT + LL H+Q+ KE+ L RG +A E
Sbjct: 1630 AALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADR 1689
Query: 145 VKVE-PMTYLGSSQNEVLNTKPDYQKILQNQSKVFD--------CMELVMDELQGSVKQL 195
VKVE + + + QNEV++ Y K+LQ + +F M+L +++L + L
Sbjct: 1690 VKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDL 1749
Query: 196 QAFMDESTQCFQKV 209
+++ Q V
Sbjct: 1750 PQIINKRINFLQSV 1763
Score = 32.0 bits (71), Expect = 0.52
Identities = 41/173 (23%), Positives = 74/173 (42%), Gaps = 18/173 (10%)
Query: 20 DLAESKRLGCLLLSSFQFSIQKLEPFLR-DTKGFSLESFRAKASSLSEELKHFADGLETD 78
+L +S+ +G LS ++ L P ++ +T E + +L + K + D +
Sbjct: 2885 ELIDSREIGASRLSR----VESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQT 2940
Query: 79 GTLQKCFED--SNGKASDFSLEASVAEMKEYITKFSLERQTWDQ--LLLHYQQEAKEILS 134
Q C E+ S S+ VA++++ + +FS +TW Q LL + +EI+
Sbjct: 2941 ---QSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVE 2997
Query: 135 RGSTEAKITEV--KVEPMTY-LGSSQNEVLNTKPD---YQKILQNQSKVFDCM 181
+I + K EP T L S NE+ D Y + K ++C+
Sbjct: 2998 CWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCL 3050
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 36.6 bits (83), Expect = 0.021
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 97 LEASVAEMKEYITKFSLERQTWDQLLLHYQ---QEAKEILSRGSTEAKITEVKVEPMTYL 153
L S +++EY T F + +T +L+L YQ +E +E L R + I + ++ L
Sbjct: 925 LRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGI--ISRL 982
Query: 154 GSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQ 212
S + E+ + Q + ++ K+ D E + L + +L M TQ ++ S+Q
Sbjct: 983 MSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARL---MSALTQLKERYSMQ 1038
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 35.4 bits (80), Expect = 0.047
Identities = 35/184 (19%), Positives = 74/184 (40%), Gaps = 26/184 (14%)
Query: 47 RDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKE 106
+D+ SL+ R + +L + K DG+E T K DS+ K + E++E
Sbjct: 775 KDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRF-LRRQELRE 833
Query: 107 YITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPD 166
E++ QL QQ+ ++I R + E+++ K
Sbjct: 834 LRFLQKEEQRAQQQLNSKLQQQREQIFRR--------------------FEQEMMSKKRQ 873
Query: 167 YQKILQN----QSKVFDCMELV-MDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQL 221
Y + ++N Q + + +E + L+ K+++ ++ FQ + K + ++
Sbjct: 874 YDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEV 933
Query: 222 DPSP 225
+ +P
Sbjct: 934 EKAP 937
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 35.0 bits (79), Expect = 0.061
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 12/160 (7%)
Query: 81 LQKCFEDSNGKASD-FSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTE 139
L K E +G + D S + KE +TK ER DQLL + + + +
Sbjct: 130 LTKLVEQGSGLSMDQHSNIRDLLRFKEEVTK---ER---DQLLSEVVKLRESLAQTTEQQ 183
Query: 140 AKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELV---MDELQGSVKQLQ 196
+ K E + Q E+ + + + + + K+ ++ + MD Q +K LQ
Sbjct: 184 QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQ 243
Query: 197 AFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQN 236
++ +S + QK+ QL ++ + L+ A++L + Q++N
Sbjct: 244 QYVQKSKEELQKLEQQLKEQKI--LNERAAKELEQFQMRN 281
>gi|94967023 disabled homolog 2 interacting protein isoform 1 [Homo
sapiens]
Length = 1132
Score = 34.7 bits (78), Expect = 0.080
Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 97 LEASVAEMKEYITKFSLERQTWDQLLLHYQ---QEAKEILSRGSTEAKITEVKVEPMTYL 153
L S +++EY T F + +T +L+L YQ +E +E L R + I + ++ L
Sbjct: 1021 LRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGI--ISRL 1078
Query: 154 GSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDE 201
S + E+ + Q + ++ K+ D E + L + +L + + +
Sbjct: 1079 MSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQ 1126
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 34.7 bits (78), Expect = 0.080
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 58 RAKASSLSEELKHFADGLETD-GTLQKCFEDSNGKASDFSL--EASVAEMKEYITKFSL- 113
+ K + +S+ + A L+ TL+ ED K+ L V + E K SL
Sbjct: 607 KTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLI 666
Query: 114 -----ERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP--MTYLGSSQNEVLNTKPD 166
ER+ W L QQ + +RG EA+I + E + S ++ L K
Sbjct: 667 FGLRTERKVWGHELA--QQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKC- 723
Query: 167 YQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQ 219
KI+ +Q++ ++ + E +K+LQ + E +C Q+ QL ++S Q
Sbjct: 724 --KIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQE---QLDEKSSQ 771
Score = 27.7 bits (60), Expect = 9.7
Identities = 30/162 (18%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Query: 11 DELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKH 70
+E R + +++ R+ C ++ +I+KL+ L++ K ++ + K + + + +
Sbjct: 705 NECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQE-KDEHIKRLQEKITEIEKCTQE 763
Query: 71 FAD--GLETDGTLQKCFEDSNGKAS-DFSLEASVAEMKEYITKFSLERQTWD---QLLLH 124
D + D L+K + K L+ E++E +S + W +LL H
Sbjct: 764 QLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCH 823
Query: 125 YQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPD 166
+ + KE+ + + K + + + L + E L++ D
Sbjct: 824 LETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDD 865
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 34.7 bits (78), Expect = 0.080
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 58 RAKASSLSEELKHFADGLETD-GTLQKCFEDSNGKASDFSL--EASVAEMKEYITKFSL- 113
+ K + +S+ + A L+ TL+ ED K+ L V + E K SL
Sbjct: 700 KTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLI 759
Query: 114 -----ERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEP--MTYLGSSQNEVLNTKPD 166
ER+ W L QQ + +RG EA+I + E + S ++ L K
Sbjct: 760 FGLRTERKVWGHELA--QQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKC- 816
Query: 167 YQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQ 219
KI+ +Q++ ++ + E +K+LQ + E +C Q+ QL ++S Q
Sbjct: 817 --KIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQE---QLDEKSSQ 864
Score = 27.7 bits (60), Expect = 9.7
Identities = 30/162 (18%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Query: 11 DELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKH 70
+E R + +++ R+ C ++ +I+KL+ L++ K ++ + K + + + +
Sbjct: 798 NECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQE-KDEHIKRLQEKITEIEKCTQE 856
Query: 71 FAD--GLETDGTLQKCFEDSNGKAS-DFSLEASVAEMKEYITKFSLERQTWD---QLLLH 124
D + D L+K + K L+ E++E +S + W +LL H
Sbjct: 857 QLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCH 916
Query: 125 YQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPD 166
+ + KE+ + + K + + + L + E L++ D
Sbjct: 917 LETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDD 958
>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 34.3 bits (77), Expect = 0.10
Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 23/154 (14%)
Query: 96 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA---KEILSRGSTEAKITEVKVEPMTY 152
SL+ ++ + KF QL+ + E KE L + + + TE +V+
Sbjct: 135 SLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVK---- 190
Query: 153 LGSSQNEVLNTKPDYQKILQ-----------NQSKVFDCMELVMDELQGSVKQLQAFMDE 201
+++E+ TK QK+ + + +K EL +D+ + +K+L ++
Sbjct: 191 --DTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLEL 248
Query: 202 STQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQ 235
ST FQ+ + KR+ + D + K+L+ ++Q
Sbjct: 249 STNSFQRQLLAERKRAYEAHDEN---KVLQKEVQ 279
>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 34.3 bits (77), Expect = 0.10
Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 23/154 (14%)
Query: 96 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEA---KEILSRGSTEAKITEVKVEPMTY 152
SL+ ++ + KF QL+ + E KE L + + + TE +V+
Sbjct: 135 SLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVK---- 190
Query: 153 LGSSQNEVLNTKPDYQKILQ-----------NQSKVFDCMELVMDELQGSVKQLQAFMDE 201
+++E+ TK QK+ + + +K EL +D+ + +K+L ++
Sbjct: 191 --DTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLEL 248
Query: 202 STQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQ 235
ST FQ+ + KR+ + D + K+L+ ++Q
Sbjct: 249 STNSFQRQLLAERKRAYEAHDEN---KVLQKEVQ 279
>gi|206597549 coiled-coil domain containing 36 [Homo sapiens]
Length = 594
Score = 33.1 bits (74), Expect = 0.23
Identities = 36/167 (21%), Positives = 77/167 (46%), Gaps = 16/167 (9%)
Query: 76 ETDGTLQKCFEDSNGKASDF----SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKE 131
++ G L++ FE+ +A D +L V+ ++E I + + + H ++
Sbjct: 111 KSKGLLEQ-FEEKKKRAKDKCDSETLYNFVSNVRESILRLQTSVEKSED---HLSSRSQS 166
Query: 132 ILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGS 191
IL T AK + ++ L E + K + ++ + K F+ + E++ +
Sbjct: 167 ILDSLETVAKTLQETIQAQNDLVF---EAVQDKGNMEQAILEMKKRFEARQGEFIEMKSN 223
Query: 192 VKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPP 238
+K L+ + + +Q FQ++ QLG+ ++ PS +L +L + PP
Sbjct: 224 LKHLEVLVAQQSQEFQQLCEQLGQLNV----PSVLAELKRL-ISVPP 265
>gi|206597547 coiled-coil domain containing 36 [Homo sapiens]
Length = 594
Score = 33.1 bits (74), Expect = 0.23
Identities = 36/167 (21%), Positives = 77/167 (46%), Gaps = 16/167 (9%)
Query: 76 ETDGTLQKCFEDSNGKASDF----SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKE 131
++ G L++ FE+ +A D +L V+ ++E I + + + H ++
Sbjct: 111 KSKGLLEQ-FEEKKKRAKDKCDSETLYNFVSNVRESILRLQTSVEKSED---HLSSRSQS 166
Query: 132 ILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGS 191
IL T AK + ++ L E + K + ++ + K F+ + E++ +
Sbjct: 167 ILDSLETVAKTLQETIQAQNDLVF---EAVQDKGNMEQAILEMKKRFEARQGEFIEMKSN 223
Query: 192 VKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPP 238
+K L+ + + +Q FQ++ QLG+ ++ PS +L +L + PP
Sbjct: 224 LKHLEVLVAQQSQEFQQLCEQLGQLNV----PSVLAELKRL-ISVPP 265
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 33.1 bits (74), Expect = 0.23
Identities = 31/132 (23%), Positives = 62/132 (46%), Gaps = 25/132 (18%)
Query: 119 DQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVF 178
++L ++E+K+ +S ++++ +V + MT L Q V + + + + + N K+
Sbjct: 327 NELRAELKEESKKAVS---LKSQLEDVSILQMT-LKEFQERVEDLEKERKLLNDNYDKLL 382
Query: 179 DCM--------------ELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPS 224
+ M EL+ ++LQ V QLQ +D + +KV ++L + Q D
Sbjct: 383 ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNED-- 440
Query: 225 PARKLLKLQLQN 236
LKL++ N
Sbjct: 441 -----LKLEVTN 447
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 32.7 bits (73), Expect = 0.30
Identities = 53/230 (23%), Positives = 98/230 (42%), Gaps = 25/230 (10%)
Query: 6 RSEIIDELSRSISVD-------LAESKRLGCLLLSSFQFSIQKL-EPFLRDTKGFSLESF 57
R + I+EL++S++ E ++L LL +Q + E L+ K S E+
Sbjct: 171 RDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETT 230
Query: 58 RAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQT 117
+ S L + ++ K ++ K ++ S E A+ E K Q
Sbjct: 231 ITQQSVSDSHLAELQEKIQQTEATNKILQE---KLNEMSYELKCAQ--ESSQKQDGTIQN 285
Query: 118 WDQLLLHYQQEAKEILS----RGSTEAKITEVKVEP-MTYLGSSQNEVLNTKPDYQKI-- 170
+ L ++E +E+ + T AK+ E+ + + L SS+ T P Q++
Sbjct: 286 LKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEG----TSPAQQQVAL 341
Query: 171 LQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 220
L QS +F C +L + +LQ V+Q + + ++ QC Q V + Q+
Sbjct: 342 LDLQSALF-CSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQK 390
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 32.7 bits (73), Expect = 0.30
Identities = 53/230 (23%), Positives = 98/230 (42%), Gaps = 25/230 (10%)
Query: 6 RSEIIDELSRSISVD-------LAESKRLGCLLLSSFQFSIQKL-EPFLRDTKGFSLESF 57
R + I+EL++S++ E ++L LL +Q + E L+ K S E+
Sbjct: 171 RDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETT 230
Query: 58 RAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQT 117
+ S L + ++ K ++ K ++ S E A+ E K Q
Sbjct: 231 ITQQSVSDSHLAELQEKIQQTEATNKILQE---KLNEMSYELKCAQ--ESSQKQDGTIQN 285
Query: 118 WDQLLLHYQQEAKEILS----RGSTEAKITEVKVEP-MTYLGSSQNEVLNTKPDYQKI-- 170
+ L ++E +E+ + T AK+ E+ + + L SS+ T P Q++
Sbjct: 286 LKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEG----TSPAQQQVAL 341
Query: 171 LQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 220
L QS +F C +L + +LQ V+Q + + ++ QC Q V + Q+
Sbjct: 342 LDLQSALF-CSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQK 390
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 32.0 bits (71), Expect = 0.52
Identities = 36/171 (21%), Positives = 76/171 (44%), Gaps = 21/171 (12%)
Query: 55 ESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLE 114
ES R + ++EL+ E +G ++ F K++ +LEA +A+++E + + + E
Sbjct: 1791 ESARQQLERQNKELRSKLH--EMEGAVKSKF-----KSTIAALEAKIAQLEEQVEQEARE 1843
Query: 115 RQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQ 174
+Q + L ++ KEIL + E K+ E E Q E N + ++
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE--------QAEKGNAR------VKQL 1889
Query: 175 SKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSP 225
+ + E + + ++LQ +DE+T+ + + ++ + P P
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPP 1940
Score = 30.0 bits (66), Expect = 2.0
Identities = 35/182 (19%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 47 RDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGK------ASDFSLEAS 100
++TK SL +A EEL+ L+ + +D GK S +LE
Sbjct: 1488 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1547
Query: 101 VAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEV 160
+ EMK + + E Q + L + + + + + + + + E + ++
Sbjct: 1548 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE------EKRRQL 1601
Query: 161 LNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 220
+Y+ L+++ K +L+G +K L+ D + + ++ QL K Q
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 221 LD 222
D
Sbjct: 1662 KD 1663
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 32.0 bits (71), Expect = 0.52
Identities = 36/171 (21%), Positives = 76/171 (44%), Gaps = 21/171 (12%)
Query: 55 ESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLE 114
ES R + ++EL+ E +G ++ F K++ +LEA +A+++E + + + E
Sbjct: 1784 ESARQQLERQNKELRSKLH--EMEGAVKSKF-----KSTIAALEAKIAQLEEQVEQEARE 1836
Query: 115 RQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQ 174
+Q + L ++ KEIL + E K+ E E Q E N + ++
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE--------QAEKGNAR------VKQL 1882
Query: 175 SKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSP 225
+ + E + + ++LQ +DE+T+ + + ++ + P P
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPP 1933
Score = 30.0 bits (66), Expect = 2.0
Identities = 35/182 (19%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 47 RDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGK------ASDFSLEAS 100
++TK SL +A EEL+ L+ + +D GK S +LE
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
Query: 101 VAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEV 160
+ EMK + + E Q + L + + + + + + + + E + ++
Sbjct: 1541 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE------EKRRQL 1594
Query: 161 LNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 220
+Y+ L+++ K +L+G +K L+ D + + ++ QL K Q
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 221 LD 222
D
Sbjct: 1655 KD 1656
>gi|4759198 homer 1 [Homo sapiens]
Length = 354
Score = 32.0 bits (71), Expect = 0.52
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 96 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGS 155
+L+ + A++ + + + + W Q L YQ+EA+ + R +TE++ + S
Sbjct: 189 TLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKR------VTELEC-----VSS 237
Query: 156 SQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSV---KQLQAFMDESTQCFQKVSVQ 212
N V K + + +Q + E ++ L+ + ++LQ D TQ Q+V ++
Sbjct: 238 QANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIR 297
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 31.6 bits (70), Expect = 0.67
Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 97 LEASVAEMKEYITKFSLERQTWDQLLLHYQQ--EAKEILSRGSTEAKITEVKVEPMTYLG 154
L S ++EY + ++ Q +LLL Y+ E E R E K +++K ++ L
Sbjct: 1141 LRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMK-SIISRLM 1199
Query: 155 SSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQL 213
+ + E+ + Q ++ + K+ D E + L + +L M TQ ++ S+Q+
Sbjct: 1200 AVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRL---MSALTQVKERYSMQV 1255
>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
Length = 1139
Score = 31.6 bits (70), Expect = 0.67
Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 97 LEASVAEMKEYITKFSLERQTWDQLLLHYQQ--EAKEILSRGSTEAKITEVKVEPMTYLG 154
L S ++EY + ++ Q +LLL Y+ E E R E K +++K ++ L
Sbjct: 1000 LRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMK-SIISRLM 1058
Query: 155 SSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQL 213
+ + E+ + Q ++ + K+ D E + L + +L M TQ ++ S+Q+
Sbjct: 1059 AVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRL---MSALTQVKERYSMQV 1114
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 31.6 bits (70), Expect = 0.67
Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 55 ESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLE 114
ES R + ++EL+ E +G ++ F K++ +LEA +A+++E + + + E
Sbjct: 1784 ESARQQLERQNKELRSKLH--EMEGAVKSKF-----KSTIAALEAKIAQLEEQVEQEARE 1836
Query: 115 RQTWDQLLLHYQQEAKEILSRGSTEAKITE 144
+Q + L ++ KEIL + E K+ E
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAE 1866
Score = 30.0 bits (66), Expect = 2.0
Identities = 35/182 (19%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 47 RDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGK------ASDFSLEAS 100
++TK SL +A EEL+ L+ + +D GK S +LE
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
Query: 101 VAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEV 160
+ EMK + + E Q + L + + + + + + + + E + ++
Sbjct: 1541 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE------EKRRQL 1594
Query: 161 LNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 220
+Y+ L+++ K +L+G +K L+ D + + ++ QL K Q
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 221 LD 222
D
Sbjct: 1655 KD 1656
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 31.6 bits (70), Expect = 0.67
Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 55 ESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLE 114
ES R + ++EL+ E +G ++ F K++ +LEA +A+++E + + + E
Sbjct: 1791 ESARQQLERQNKELRSKLH--EMEGAVKSKF-----KSTIAALEAKIAQLEEQVEQEARE 1843
Query: 115 RQTWDQLLLHYQQEAKEILSRGSTEAKITE 144
+Q + L ++ KEIL + E K+ E
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAE 1873
Score = 30.0 bits (66), Expect = 2.0
Identities = 35/182 (19%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 47 RDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGK------ASDFSLEAS 100
++TK SL +A EEL+ L+ + +D GK S +LE
Sbjct: 1488 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1547
Query: 101 VAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEV 160
+ EMK + + E Q + L + + + + + + + + E + ++
Sbjct: 1548 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE------EKRRQL 1601
Query: 161 LNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQ 220
+Y+ L+++ K +L+G +K L+ D + + ++ QL K Q
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 221 LD 222
D
Sbjct: 1662 KD 1663
>gi|50658071 phosphodiesterase 4D interacting protein isoform 5
[Homo sapiens]
Length = 1132
Score = 30.8 bits (68), Expect = 1.2
Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 23/141 (16%)
Query: 83 KCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKI 142
KC ++S+ K + ++ +KE T S ER+T ++ + I + T AK+
Sbjct: 433 KCAQESSQKQ-----DGTIQNLKE--TLKSRERET--------EELYQVIEGQNDTMAKL 477
Query: 143 TEVKVEP-MTYLGSSQNEVLNTKPDYQKI--LQNQSKVFDCMELVMDELQGSVKQLQAFM 199
E+ + + L SS+ T P Q++ L QS +F C +L + +LQ V+Q + +
Sbjct: 478 REMLHQSQLGQLHSSEG----TSPAQQQVALLDLQSALF-CSQLEIQKLQRVVRQKERQL 532
Query: 200 DESTQCFQKVSVQLGKRSMQQ 220
++ QC Q V + Q+
Sbjct: 533 ADAKQCVQFVEAAAHESEQQK 553
>gi|4758104 cytochrome P450, family 7, subfamily B, polypeptide 1
[Homo sapiens]
Length = 506
Score = 30.4 bits (67), Expect = 1.5
Identities = 19/94 (20%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 31 LLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNG 90
+L FQ+ + +++ K S F K + + + + L C++ G
Sbjct: 93 ILDPFQYQL-----VIKNHKQLSFRVFSNKLLEKAFSISQLQKNHDMNDELHLCYQFLQG 147
Query: 91 KASDFSLEASVAEMKEYITKFSLERQTWDQLLLH 124
K+ D LE+ + +K+ L+ +WD L+
Sbjct: 148 KSLDILLESMMQNLKQVFEPQLLKTTSWDTAELY 181
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 30.4 bits (67), Expect = 1.5
Identities = 51/244 (20%), Positives = 95/244 (38%), Gaps = 27/244 (11%)
Query: 23 ESKRLGCLLLSSFQFSIQKLEPFLRDTKGFS--LESFRAKASSLSEELKHFADGLETDGT 80
+S L LL S Q+ E F + + L S R + S L E + +E +
Sbjct: 85 DSLELQGLLEDERLASAQQAEVFTKQIQQLQGELRSLREEISLLEHEKESELKEIEQELH 144
Query: 81 LQKCFEDSNGKASDFSL---EASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGS 137
L + S +A++ S E+ +A ++E + + E + +++ Y+ E + R
Sbjct: 145 LAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIASL--RAE 202
Query: 138 TEAKITEVKVEPMTYLGSS-----QNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSV 192
E K +E P LG S Q E+ + Y + ++ + ++ L G +
Sbjct: 203 MEMKSSE----PSGSLGLSDYSGLQEELQELRERYHFL----NEEYRALQESNSSLTGQL 254
Query: 193 KQLQAFMDE-------STQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGS 245
L++ + +Q S + M L+P P +LL+ QL++
Sbjct: 255 ADLESERTQRATERWLQSQTLSMTSAESQTSEMDFLEPDPEMQLLRQQLRDAEEQMHGMK 314
Query: 246 GSCQ 249
CQ
Sbjct: 315 NKCQ 318
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,184,914
Number of Sequences: 37866
Number of extensions: 316483
Number of successful extensions: 1086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 1036
Number of HSP's gapped (non-prelim): 104
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.