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Search of human proteins with 223468597
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223468597 integrin alpha-V isoform 3 precursor [Homo
sapiens]
(1012 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 2039 0.0
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 2019 0.0
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 1894 0.0
gi|49170034 integrin, alpha 8 [Homo sapiens] 899 0.0
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 851 0.0
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 590 e-168
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 308 1e-83
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 307 3e-83
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 288 1e-77
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 285 2e-76
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 263 8e-70
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 256 8e-68
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 248 2e-65
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 246 1e-64
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 240 6e-63
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 193 6e-49
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 189 9e-48
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 164 3e-40
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 163 9e-40
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 161 3e-39
gi|34452173 integrin alpha X precursor [Homo sapiens] 157 4e-38
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 149 2e-35
gi|148728188 integrin, alpha E precursor [Homo sapiens] 146 8e-35
gi|62548866 integrin, alpha D precursor [Homo sapiens] 139 2e-32
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 120 5e-27
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 119 1e-26
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 62 4e-09
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 50 8e-06
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su... 32 3.9
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su... 32 3.9
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 2039 bits (5282), Expect = 0.0
Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)
Query: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA
Sbjct: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60
Query: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120
SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS
Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120
Query: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISD 180
HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISD
Sbjct: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISD 180
Query: 181 QVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRA 240
QVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRA
Sbjct: 181 QVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRA 240
Query: 241 ARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSD 300
ARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSD
Sbjct: 241 ARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSD 300
Query: 301 GKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGG 360
GKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGG
Sbjct: 301 GKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGG 360
Query: 361 EDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 420
EDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA
Sbjct: 361 EDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 420
Query: 421 FGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGV 480
FGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGV
Sbjct: 421 FGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGV 480
Query: 481 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 540
LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES
Sbjct: 481 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 540
Query: 541 EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL 600
EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL
Sbjct: 541 EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL 600
Query: 601 EVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARL 660
EVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARL
Sbjct: 601 EVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARL 660
Query: 661 SCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKV 720
SCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKV
Sbjct: 661 SCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKV 720
Query: 721 SPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNG 780
SPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNG
Sbjct: 721 SPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNG 780
Query: 781 PSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDT 840
PSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDT
Sbjct: 781 PSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDT 840
Query: 841 VAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTE 900
VAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTE
Sbjct: 841 VAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTE 900
Query: 901 TFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWV 960
TFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWV
Sbjct: 901 TFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWV 960
Query: 961 IILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET 1012
IILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
Sbjct: 961 IILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET 1012
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 2019 bits (5231), Expect = 0.0
Identities = 1011/1048 (96%), Positives = 1012/1048 (96%), Gaps = 36/1048 (3%)
Query: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA
Sbjct: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60
Query: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120
SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS
Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120
Query: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSR----- 175
HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRS+
Sbjct: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180
Query: 176 -------------------------------QLISDQVAEIVSKYDPNVYSIKYNNQLAT 204
QLISDQVAEIVSKYDPNVYSIKYNNQLAT
Sbjct: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
Query: 205 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 264
RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE
Sbjct: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300
Query: 265 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 324
QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK
Sbjct: 301 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360
Query: 325 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 384
LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI
Sbjct: 361 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420
Query: 385 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444
LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY
Sbjct: 421 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480
Query: 445 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 504
PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR
Sbjct: 481 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540
Query: 505 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 564
ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD
Sbjct: 541 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600
Query: 565 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 624
TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK
Sbjct: 601 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660
Query: 625 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 684
AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
Sbjct: 661 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720
Query: 685 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 744
TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP
Sbjct: 721 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780
Query: 745 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 804
DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY
Sbjct: 781 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840
Query: 805 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 864
ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH
Sbjct: 841 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900
Query: 865 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 924
TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE
Sbjct: 901 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960
Query: 925 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 984
FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF
Sbjct: 961 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020
Query: 985 FKRVRPPQEEQEREQLQPHENGEGNSET 1012
FKRVRPPQEEQEREQLQPHENGEGNSET
Sbjct: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 1894 bits (4907), Expect = 0.0
Identities = 949/986 (96%), Positives = 950/986 (96%), Gaps = 36/986 (3%)
Query: 63 RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ 122
RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ
Sbjct: 17 RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ 76
Query: 123 WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSR------- 175
WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRS+
Sbjct: 77 WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ 136
Query: 176 -----------------------------QLISDQVAEIVSKYDPNVYSIKYNNQLATRT 206
QLISDQVAEIVSKYDPNVYSIKYNNQLATRT
Sbjct: 137 GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT 196
Query: 207 AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM 266
AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM
Sbjct: 197 AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM 256
Query: 267 AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN 326
AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN
Sbjct: 257 AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN 316
Query: 327 GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE 386
GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE
Sbjct: 317 GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE 376
Query: 387 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 446
GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS
Sbjct: 377 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 436
Query: 447 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL 506
ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL
Sbjct: 437 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL 496
Query: 507 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 566
FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT
Sbjct: 497 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 556
Query: 567 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ 626
GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ
Sbjct: 557 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ 616
Query: 627 NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ 686
NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ
Sbjct: 617 NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ 676
Query: 687 LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH 746
LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH
Sbjct: 677 LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH 736
Query: 747 IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL 806
IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL
Sbjct: 737 IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL 796
Query: 807 HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL 866
HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL
Sbjct: 797 HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL 856
Query: 867 GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP 926
GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP
Sbjct: 857 GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP 916
Query: 927 YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK 986
YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK
Sbjct: 917 YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK 976
Query: 987 RVRPPQEEQEREQLQPHENGEGNSET 1012
RVRPPQEEQEREQLQPHENGEGNSET
Sbjct: 977 RVRPPQEEQEREQLQPHENGEGNSET 1002
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 899 bits (2322), Expect = 0.0
Identities = 478/1052 (45%), Positives = 662/1052 (62%), Gaps = 67/1052 (6%)
Query: 12 GPRG--LPLLLS--------GLLL--PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPS 59
GPRG PL+ G+LL P C+AFNLDV+ YSGP+GSYFG+AVDF +P
Sbjct: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
Query: 60 ASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSS--TRRCQPIEFDATGNRDYAKD---D 114
A + +LVGAPKANT+QP IVEGG V C W + + +C+ I FD T NR + +
Sbjct: 68 ARTAS-VLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKE 126
Query: 115 PLEFKSHQWFGASVRSKQDKILACAPLYHWRT-EMKQEREPVGTCF--LQDGTKTVEYAP 171
P+EFKS+QWFGA+V++ + K++ACAPLYHWRT + E++PVGTC+ +Q+ + E++P
Sbjct: 127 PIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSP 186
Query: 172 CRSR------------------------------------QLISDQVAEIVSKYDPNVYS 195
CR+ Q+I+ VA+I++ Y
Sbjct: 187 CRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDIL 246
Query: 196 IKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNM 255
K + T A A +DDSYLGYSVA G+F GD + V+G+PR A+ G V I + +M
Sbjct: 247 RKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDM 306
Query: 256 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 315
+ + NFTGEQMA+YFG++V +D+N D DV +GAPLFM+R + +EVGQ+ + LQ
Sbjct: 307 TFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQV 366
Query: 316 ASGDFQTTK-LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 374
+S F+ + L G E F RFGSA+A LGDL+QDG+NDIAI P+ G+D++G V I+NG
Sbjct: 367 SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426
Query: 375 TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 434
GLN PSQ+L+G WA+ ++P FG++++G +DIDKN YPDLIVGAFG + +YRARPV
Sbjct: 427 DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486
Query: 435 ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 494
+TV+A L ++P I+N +NKTC +P + +CF++R C G+ + + E+ LD
Sbjct: 487 VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA-NTIVLMAEVQLD 545
Query: 495 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 554
LKQKGAI+R LFL + + I R QC++ I YLRDE+EFRDKL+PI I +
Sbjct: 546 SLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLN 605
Query: 555 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 614
Y LD T + ++PILN + +S QAHIL+DCGEDN+C P L++S D+ ++ IG
Sbjct: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIG 665
Query: 615 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 674
D+N L LI+ A+N+GEGAYEAEL V IP +AD++G+ RNN+ LSC +K EN TR VV
Sbjct: 666 DENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVV 725
Query: 675 CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 734
CDLGNPM +GT GLRF+V + + + S+ FDLQI+SSN + S VS ++++ +A
Sbjct: 726 CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVA 785
Query: 735 AVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWP 794
VEIRGVS P I LPI NWE +E P EE+VGP+V+HIYEL N GPS+ S +L + WP
Sbjct: 786 QVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWP 845
Query: 795 YKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIK-ISSLQTTEKNDTVAGQGERDHLITK 853
+ + LLYI H GP+ C + INP IK +S + T + HL+ K
Sbjct: 846 FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRK 905
Query: 854 RDLALSE----GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 909
RD+ + E L C +CL+I C VGRL+ G+SA+L V+S LW TF+ ++N
Sbjct: 906 RDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKND- 964
Query: 910 HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 969
Y+L S SF V + PY + P + S + T+V W +P+WVIILA+L GL
Sbjct: 965 -PYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGL 1023
Query: 970 LLLAVLVFVMYRMGFFKRVRPPQEEQ-EREQL 1000
L+LA+L +++ GFF R RPPQE+ +REQL
Sbjct: 1024 LVLAILTLALWKCGFFDRARPPQEDMTDREQL 1055
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 851 bits (2198), Expect = 0.0
Identities = 461/1049 (43%), Positives = 647/1049 (61%), Gaps = 73/1049 (6%)
Query: 8 RLRLGPRGLPLLLSGLLL-----PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASS 62
+LR GPR P LL LLL P FNLD ++PA SGP GS+FGF+V+F+ P
Sbjct: 14 QLRWGPRRRPPLLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDG 73
Query: 63 RMFLLVGAPKANTTQPGIVEGGQVLKCDW-SSTRRCQPIEFDATGNR-------DYAKDD 114
+ +LVGAPKANT+QPG+++GG V C W +S +C PIEFD+ G+R ++
Sbjct: 74 -VSVLVGAPKANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEE 132
Query: 115 PLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDG--TKTVEYAPC 172
P+E+KS QWFGA+VR+ ILACAPLY WRTE + +PVGTC+L T+ +EYAPC
Sbjct: 133 PVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAPC 192
Query: 173 RSR------------------------------------QLISDQVAEIVSKYDPNVYSI 196
RS Q++S +I Y P
Sbjct: 193 RSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLIN 252
Query: 197 KYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMS 256
QL TR A +I+DDSYLGYSVAVG+F+GD +DFV+GVP+ T G V I +G ++
Sbjct: 253 LVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSDIR 312
Query: 257 SLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRA 316
SLYNF+GEQMA+YFG++VAATD+NGD D+ +GAPL MDR DG+ QEVG+V V LQ
Sbjct: 313 SLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQHP 372
Query: 317 SG--DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 374
+G T L G + F RFGS++ PLGDLDQDG+ND+AI AP+GGE ++G+V++F G
Sbjct: 373 AGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGP 432
Query: 375 TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 434
GL + PSQ+L+ WAA P FG +++G D+D NGYPDLIVG+FGVD+A++YR RP+
Sbjct: 433 GGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPI 492
Query: 435 ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 494
++ +A L ++P++ N + ++CSL G V+C N+ FCL A GK V + F VEL LD
Sbjct: 493 VSASASLTIFPAMFNPEERSCSLEGN--PVACINLSFCLNASGKHVAD-SIGFTVELQLD 549
Query: 495 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 554
KQKG +RRALFL SR + ++ + I G C E+ YLR+ESEFRDKL+PI I +
Sbjct: 550 WQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALN 609
Query: 555 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 614
+ LD + D+ GL+P L+ + + I +A ILLDCGEDN+C P L++ V +Q +Y+G
Sbjct: 610 FSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHVYLG 669
Query: 615 DDNPLTLIVKAQNQGE-GAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQV 673
D N L L AQN GE GAYEAEL V+ P +A++ G+VR+ + LSC + NQ+R +
Sbjct: 670 DKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLL 729
Query: 674 VCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVL 733
VCDLGNPMKAG L GLRF+V + +++FD QI S NL + S VVS ++ +
Sbjct: 730 VCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQ 789
Query: 734 AAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQW 793
A V + GVS P+ + P+ +W ++ P+ EED+GP V H+YEL N GPSS S+ +L L
Sbjct: 790 AQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSC 849
Query: 794 PYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITK 853
P LLY+ + G +NCT++ INP +++ + ++ Q +R+
Sbjct: 850 PQALEGQQLLYVTR--VTG-LNCTTNHPINPKGLEL------DPEGSLHHQQKRE--APS 898
Query: 854 RDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 913
R A S I L C A+C ++ C++G L + +S L + +W +TF+ +E+Q +S
Sbjct: 899 RSSASSGPQI--LKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQ--PFS 954
Query: 914 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 973
L+ A + ++ PY+ LP + V T V W VP+W+IILA+L GLLLL
Sbjct: 955 LQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLG 1014
Query: 974 VLVFVMYRMGFFKRVRPPQEEQEREQLQP 1002
+L++++Y++GFFKR P E+ QL+P
Sbjct: 1015 LLIYILYKLGFFKRSLPYGTAMEKAQLKP 1043
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 590 bits (1520), Expect = e-168
Identities = 387/1045 (37%), Positives = 547/1045 (52%), Gaps = 90/1045 (8%)
Query: 18 LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77
LLL P A NLD Y+GP GS FGF++DF S R+ ++VGAP+ T
Sbjct: 19 LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75
Query: 78 PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135
P E G V C W + +C + FD L+ FK+ Q GASV S D I
Sbjct: 76 PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135
Query: 136 LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSRQL------------- 177
+ACAP HW K E + PVG+CFL + + EY+PCR L
Sbjct: 136 VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195
Query: 178 -------------------------------ISDQVAEIVSKYDPNVYSIKYNNQ-LATR 205
VA+I S Y P + ++Q L+
Sbjct: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255
Query: 206 TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 264
++ + D Y GYSVAVG+F+GD ++V G P + TLG V I D L+ GE
Sbjct: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314
Query: 265 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 320
QMA+YFG SVA TD+NGD D+ +GAPL+M+ +D KL EVG+V + LQ A G
Sbjct: 315 QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373
Query: 321 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 380
+ L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG +G V +F G+S GL +
Sbjct: 374 PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433
Query: 381 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 440
PSQ+L+ + S +FG+S++GA DID NGYPDLIVGA+G ++ +YRA+PV+ +
Sbjct: 434 PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490
Query: 441 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 500
L V S LN K+C LP T VSCFN++ C+ A G + P+KL+ EL LD+ K +
Sbjct: 491 LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548
Query: 501 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 560
RR L L S+ + N+ + C +A+LRDE++FRDKL+PI + + L
Sbjct: 549 G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607
Query: 561 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 620
A G+ P + ++ Q I+LDCGED+VC P+L+++ + +G DN L
Sbjct: 608 EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663
Query: 621 LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 680
L + A N+GEGAYEAEL V +P A ++ + N E RL C K EN+TR V+C+LGNP
Sbjct: 664 LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723
Query: 681 MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 740
MK Q+ + SV E SV F LQI+S N + S +V V + A VE+RG
Sbjct: 724 MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783
Query: 741 VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 800
S P + + E ++N + + GP V+H YEL NNGP + + L + P + +
Sbjct: 784 NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841
Query: 801 TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 860
LLYIL G + C +NPL++ L + +RD +R + L E
Sbjct: 842 DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896
Query: 861 -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 913
D + C A C + C + + RG+ A++ V + LW + + +
Sbjct: 897 PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954
Query: 914 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 973
L+S A FNV PY P+ V T + ++ +P+W +++ VL GLLLL
Sbjct: 955 LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012
Query: 974 VLVFVMYRMGFFKRVRPPQEEQERE 998
+LV M+++GFFKR RPP EE + E
Sbjct: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 308 bits (790), Expect = 1e-83
Identities = 295/1075 (27%), Positives = 491/1075 (45%), Gaps = 144/1075 (13%)
Query: 19 LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75
L +GLL L AFNLD D+ G GS FGF++ + + LLVGAP+A
Sbjct: 12 LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71
Query: 76 T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133
Q GG + CD ++ C IEFD D E K QW G +V+S+
Sbjct: 72 LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124
Query: 134 --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPC----RSRQL 177
K++ CA Y R + KQE R+ G C+ ++D +++ C R +
Sbjct: 125 GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184
Query: 178 ISDQVAEIVSKYDPNVYSI------KYNNQLATRTAQA--------IFDD---------- 213
+ + + + + I YN + R Q IF+D
Sbjct: 185 FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETE 244
Query: 214 -----------SYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL-- 258
SYLG+S+ G + D I FVSG PRA + +V + + L
Sbjct: 245 HDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHLLP 303
Query: 259 -YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS 317
+ F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG++ V ++ Q
Sbjct: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQGRW 361
Query: 318 GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 377
+ + +LNG + + FG A+ +GD++QDG+ DIA+ APY D G V+I++G + G+
Sbjct: 362 NNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGI 417
Query: 378 NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 437
N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+ D ++R+RPVI +
Sbjct: 418 NTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVINI 470
Query: 438 NAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELLLD 494
+ V P+ ++ KT C P C V+ C + A+ G P ++ L +
Sbjct: 471 QKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLEAE 525
Query: 495 KLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIF 552
K ++K G R F S P +++ +T+ R C E +L+D RDKL PI I
Sbjct: 526 KERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIPIT 583
Query: 553 MEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV--- 604
+ R + PILN P H L + CG+DNVC L++
Sbjct: 584 ASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFC 643
Query: 605 --DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELIVS 640
+ +Q K + + D + L + N G+ A+EA+LI +
Sbjct: 644 TREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIAT 703
Query: 641 IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 700
P + R A + Q C+LGNP K + + L S + +
Sbjct: 704 FPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTF 762
Query: 701 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 760
+ +L++++++ D ++P+ + K + + + + GV+ P ++ ++
Sbjct: 763 DTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQAM 820
Query: 761 ETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--PMN 815
++E++VG ++++ + + N G ++ A L++QWP + +N LLY++ + G +
Sbjct: 821 KSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVT 880
Query: 816 CTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQCL 874
C EIN L + S ++ T E+ ++ +E TL C V C+
Sbjct: 881 CEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVNCV 935
Query: 875 KIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIED 934
I C + LD S IL +S LW TF+ + ++ + + A +V +N+ + +
Sbjct: 936 NIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRLPN 992
Query: 935 ITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 989
VT + + VP W+I++A+LAG+L+LA+LVF++++ GFFKR R
Sbjct: 993 AGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 307 bits (787), Expect = 3e-83
Identities = 294/1073 (27%), Positives = 490/1073 (45%), Gaps = 144/1073 (13%)
Query: 19 LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75
L +GLL L AFNLD D+ G GS FGF++ + + LLVGAP+A
Sbjct: 12 LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71
Query: 76 T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133
Q GG + CD ++ C IEFD D E K QW G +V+S+
Sbjct: 72 LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124
Query: 134 --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPC----RSRQL 177
K++ CA Y R + KQE R+ G C+ ++D +++ C R +
Sbjct: 125 GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184
Query: 178 ISDQVAEIVSKYDPNVYSI------KYNNQLATRTAQA--------IFDD---------- 213
+ + + + + I YN + R Q IF+D
Sbjct: 185 FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETE 244
Query: 214 -----------SYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL-- 258
SYLG+S+ G + D I FVSG PRA + +V + + L
Sbjct: 245 HDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHLLP 303
Query: 259 -YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS 317
+ F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG++ V ++ Q
Sbjct: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQGRW 361
Query: 318 GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 377
+ + +LNG + + FG A+ +GD++QDG+ DIA+ APY D G V+I++G + G+
Sbjct: 362 NNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGI 417
Query: 378 NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 437
N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+ D ++R+RPVI +
Sbjct: 418 NTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVINI 470
Query: 438 NAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELLLD 494
+ V P+ ++ KT C P C V+ C + A+ G P ++ L +
Sbjct: 471 QKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLEAE 525
Query: 495 KLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIF 552
K ++K G R F S P +++ +T+ R C E +L+D RDKL PI I
Sbjct: 526 KERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIPIT 583
Query: 553 MEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV--- 604
+ R + PILN P H L + CG+DNVC L++
Sbjct: 584 ASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFC 643
Query: 605 --DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELIVS 640
+ +Q K + + D + L + N G+ A+EA+LI +
Sbjct: 644 TREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIAT 703
Query: 641 IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 700
P + R A + Q C+LGNP K + + L S + +
Sbjct: 704 FPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTF 762
Query: 701 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 760
+ +L++++++ D ++P+ + K + + + + GV+ P ++ ++
Sbjct: 763 DTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQAM 820
Query: 761 ETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--PMN 815
++E++VG ++++ + + N G ++ A L++QWP + +N LLY++ + G +
Sbjct: 821 KSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVT 880
Query: 816 CTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQCL 874
C EIN L + S ++ T E+ ++ +E TL C V C+
Sbjct: 881 CEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVNCV 935
Query: 875 KIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIED 934
I C + LD S IL +S LW TF+ + ++ + + A +V +N+ + +
Sbjct: 936 NIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRLPN 992
Query: 935 ITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR 987
VT + + VP W+I++A+LAG+L+LA+LVF++++ GFFKR
Sbjct: 993 AGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 288 bits (738), Expect = 1e-77
Identities = 310/1114 (27%), Positives = 498/1114 (44%), Gaps = 173/1114 (15%)
Query: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
R R G G+ L LL+ L AFNLDV G GS FGF+V
Sbjct: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64
Query: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
+ +LLVGAP+A PG G + C S C ++ D D E
Sbjct: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117
Query: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D
Sbjct: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177
Query: 166 TVEYAPCRSRQLISDQVA----EIVSKYDPNVYSIKYN---------------------N 200
E+ C R +Q + + P+ + + + +
Sbjct: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPD 237
Query: 201 QLATRT----------AQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLG 245
QL +T A + +SYLG+S+ +G G+ FV+G PRA G
Sbjct: 238 QLVYKTLDPADRLPGPAGDLALNSYLGFSID----SGKGLVRAEELSFVAGAPRANHK-G 292
Query: 246 MVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGK 302
V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R +
Sbjct: 293 AVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG 352
Query: 303 LQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGG 360
G V V L + +L G + FG ++A LGDL+QDGF DIA+ AP+ G
Sbjct: 353 ----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDG 407
Query: 361 EDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 420
+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+VG+
Sbjct: 408 DGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGS 461
Query: 421 FGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGK 478
D A+L+RARP++ V+ + + P ++ + C+ + C ++R C A
Sbjct: 462 L-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPS 516
Query: 479 GVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---A 534
P L++ ++ D+ + +G + R FL SR+ K+ L + + A
Sbjct: 517 SYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDA 574
Query: 535 YLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILL 588
+ + +DKL I + + Y L R A GL PILN P+ + H L
Sbjct: 575 MFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLK 634
Query: 589 D-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI----------------- 622
CGED +C+ L++ D++ + + + D L
Sbjct: 635 QGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNL 694
Query: 623 ----VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLG 678
+ Q G+ A+EA+L+V +P + GV + A L EN + V C+LG
Sbjct: 695 PSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELG 751
Query: 679 NPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEI 738
NPMK G Q+ L S S T ++ +L + + + ++ VS + + + + I
Sbjct: 752 NPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSI 809
Query: 739 RGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPY 795
G++ P +F + E ++E DVG V++ + N G S + A L++ WP+
Sbjct: 810 AGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPH 867
Query: 796 KY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAG 843
+ N LLY + +++G P ++++ + L+ E+ + G
Sbjct: 868 EIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PG 925
Query: 844 QGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTET 901
+ + + + + TL C G A C+ C + DR +A+L+V LW T
Sbjct: 926 ERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNST 983
Query: 902 FMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPV 958
F+ + + S + A+ V + KNL + D ST++ V + P + VP
Sbjct: 984 FLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPW 1038
Query: 959 WVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 992
WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 1039 WVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 285 bits (728), Expect = 2e-76
Identities = 311/1118 (27%), Positives = 496/1118 (44%), Gaps = 177/1118 (15%)
Query: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
R R G G+ L LL+ L AFNLDV G GS FGF+V
Sbjct: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64
Query: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
+ +LLVGAP+A PG G + C S C ++ D D E
Sbjct: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117
Query: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D
Sbjct: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177
Query: 166 TVEYAPCRSRQLISDQVA----EIVSKYDPNVYSI------KYNNQLATRT---AQAIFD 212
E+ C R +Q + + P+ + + YN + R AQ D
Sbjct: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSAD 237
Query: 213 --------------------------DSYLGYSVAVGDFNGDGID-----DFVSGVPRAA 241
+SY G+S+ +G G+ FV+G PRA
Sbjct: 238 LAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSID----SGKGLVRAEELSFVAGAPRAN 293
Query: 242 RTLGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRG 298
G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R
Sbjct: 294 HK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQ 352
Query: 299 SDGKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAA 356
+ G V V L + +L G + FG ++A LGDL+QDGF DIA+ A
Sbjct: 353 EELG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGA 407
Query: 357 PYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDL 416
P+ G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL
Sbjct: 408 PFDGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDL 461
Query: 417 IVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK-- 474
+VG+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C
Sbjct: 462 LVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYI 516
Query: 475 ADGKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI 533
A P L++ ++ D+ + +G + R FL SR+ K+ L + +
Sbjct: 517 AVPSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRV 574
Query: 534 ---AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQA 584
A + + +DKL I + + Y L R A GL PILN P+ +
Sbjct: 575 CGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEI 634
Query: 585 HILLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI------------- 622
H L CGED +C+ L++ D++ + + + D L
Sbjct: 635 HFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELM 694
Query: 623 --------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 674
+ Q G+ A+EA+L+V +P + GV + A L EN + V
Sbjct: 695 VTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVE 751
Query: 675 CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 734
C+LGNPMK G Q+ L S S T ++ +L + + + ++ VS + + +
Sbjct: 752 CELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIEL 809
Query: 735 AVEIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHL 791
+ I G++ P +F + E ++E DVG V++ + N G S + A L++
Sbjct: 810 PLSIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNI 867
Query: 792 QWPYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKND 839
WP++ N LLY + +++G P ++++ + L+ E+ +
Sbjct: 868 MWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE 927
Query: 840 TVAGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLL 897
G+ + + + + TL C G A C+ C + DR +A+L+V L
Sbjct: 928 --PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRL 983
Query: 898 WTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM--- 954
W TF+ + + S + A+ V + KNL + D ST++ V + P +
Sbjct: 984 WNSTFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAE 1038
Query: 955 PVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 992
VP WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 1039 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 263 bits (671), Expect = 8e-70
Identities = 280/1082 (25%), Positives = 472/1082 (43%), Gaps = 121/1082 (11%)
Query: 1 MAFPPRRR---LRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFV 57
MA+ RR R R +LL L +P R +N+D +S Y GP + FG++V +
Sbjct: 1 MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSV--VL 58
Query: 58 PSASSRMFLLVGAPKAN-TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAKDD 114
S + +LLVGAP AN ++ G + +C + C+ ++ + K
Sbjct: 59 HSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTC 118
Query: 115 PLEFKSHQWFGASVR---SKQDKILACAPLYHWRT--EMKQERE-PVGTCF--------- 159
LE + +QW G ++ + I+ C + W+ +K E + P G C+
Sbjct: 119 -LEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTE 175
Query: 160 --------LQDGTKTV--EYAPCRSRQLISDQVAEIVSKYDPN---------VYSIKYNN 200
QD K +A C++ + S +++ P VY+I N
Sbjct: 176 LSKRIAPCYQDYVKKFGENFASCQAG-ISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNK 234
Query: 201 QLATRTAQ-AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY--DGKNMSS 257
A Q + SYLGYSV G F + V G P+ + +G YI+ D K ++
Sbjct: 235 YKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQ-IGKAYIFSIDEKELNI 293
Query: 258 LYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS 317
L+ G+++ +YFG SV A D+N D ++D+ +GAP+ ++E G+V V + S
Sbjct: 294 LHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTIREEGRVFVYINSGS 347
Query: 318 G---DFQTTKLNGFEVFA-RFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGR 373
G + T L G + +A RFG +I LGD+D DGF D+AI AP +D +G +YI+NGR
Sbjct: 348 GAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE-DDLQGAIYIYNGR 406
Query: 374 STGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARP 433
+ G+++ SQ +EG ++S+ FG S+ G D D NGY D+ VGAF D A+L R RP
Sbjct: 407 ADGISSTFSQRIEGLQISKSLS-MFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRP 465
Query: 434 VITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLL 493
V+ V+A L +P +N+ C G C ++ C GK V P + + L
Sbjct: 466 VVIVDASLS-HPESVNRTKFDCVENG--WPSVCIDLTLCFSYKGKEV-PGYIVLFYNMSL 521
Query: 494 DKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFM 553
D ++ + R F + + C A++R + RD LTPI I
Sbjct: 522 DVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMR--KDVRDILTPIQIEA 579
Query: 554 EYRL-----DYRTAADTTGLQPILNQFTPANISRQA-HILLDCGEDNVCKPKLEVS---- 603
Y L R+ + LQPIL Q +I ++ + C +N C L+VS
Sbjct: 580 AYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIG 638
Query: 604 -VDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARL 660
+ + K Y +G L L V N G+ AYE L V +P+ FI ++ E ++
Sbjct: 639 FLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEE--KQI 696
Query: 661 SCAFKTENQTRQVVCDLGN---PMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLF 717
+C + Q+ C +G + + L S ++E D S+ ++
Sbjct: 697 NCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEM 756
Query: 718 DKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPV--VQHIYE 775
D + +V +A+ E++ H F+ ++ + N E E + V + +
Sbjct: 757 DNLK---HSRVTVAIPLKYEVK---LTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFH 810
Query: 776 LRNNGPSSFSKAMLHLQWPYKYNNNT--LLYILHYD-IDGPMNCTSDMEINPLRIKISSL 832
+ N G S + + P ++ T L IL G + + + L + S++
Sbjct: 811 VINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAM 870
Query: 833 QTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILY 892
QT + V + D KR L + D H CL +C G+++ GK A ++
Sbjct: 871 QTLK--GIVRFLSKTD----KRLLYCIKADPH--------CLNFLCNFGKMESGKEASVH 916
Query: 893 VKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGI--Q 950
++ E + ++++ FP N + ++ V + G+ Q
Sbjct: 917 IQLEGRPSILEMDETSALKFEIRATG------FPEPNPRVIELNKDENVAHVLLEGLHHQ 970
Query: 951 PAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR-VRPPQEEQEREQLQPHENGEGN 1009
+ +I ++L GL++L ++ +VM++ GFFKR + +E+ R + N + N
Sbjct: 971 RPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYINSKSN 1030
Query: 1010 SE 1011
+
Sbjct: 1031 DD 1032
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 256 bits (654), Expect = 8e-68
Identities = 243/852 (28%), Positives = 403/852 (47%), Gaps = 111/852 (13%)
Query: 213 DSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMVYIYDGKNMSSLYN---FTGE 264
+SY G+S+ +G G+ FV+G PRA G V I + S L +GE
Sbjct: 167 NSYFGFSID----SGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVMLSGE 221
Query: 265 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS--GDFQT 322
++ + FG+S+A D+N D + D+ +GAP F +R + G V V L +
Sbjct: 222 RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHWAGISP 277
Query: 323 TKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPS 382
+L G + FG ++A LGDL+QDGF DIA+ AP+ G+ K V+I++G S G+ A PS
Sbjct: 278 LRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK---VFIYHGSSLGVVAKPS 333
Query: 383 QILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLE 442
Q+LEG+ SFGYS+ G+ D+D N YPDL+VG+ D A+L+RARP++ V+ +
Sbjct: 334 QVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVS 389
Query: 443 VYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGVLPR-KLNFQVELLLDKLKQK 499
+ P ++ + C+ + C ++R C A P L++ ++ D+ + +
Sbjct: 390 IAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTDR-RLR 444
Query: 500 GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYLRDESEFRDKLTPITIFMEYR 556
G + R FL SR+ K+ L + + A + + +DKL I + + Y
Sbjct: 445 GQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS 503
Query: 557 LD---YRTAADTTGL---QPILNQFTPANISRQAHILLD-CGEDNVCKPKLEV------- 602
L R A GL PILN P+ + H L CGED +C+ L++
Sbjct: 504 LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCT 563
Query: 603 -SVDSDQKKIYIGDDNPLTLI---------------------VKAQNQGEGAYEAELIVS 640
D++ + + + D L + Q G+ A+EA+L+V
Sbjct: 564 RVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM 623
Query: 641 IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 700
+P + GV + A L EN + V C+LGNPMK G Q+ L S S
Sbjct: 624 LPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNPMKRGAQVTFYLILSTSGISI 680
Query: 701 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLP-IPNWEHKEN 759
T ++ +L + + + ++ VS + + + + I G++ P +F + E
Sbjct: 681 ETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERA-- 736
Query: 760 PETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY-NNNTLLYILHYDIDG---- 812
++E DVG V++ + N G S + A L++ WP++ N LLY + +++G
Sbjct: 737 MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGP 796
Query: 813 -------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHT 865
P ++++ + L+ E+ + G+ + + + + T
Sbjct: 797 GQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGERQEPSMSWWPVSSAEKKKNIT 854
Query: 866 LGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVI 923
L C G A C+ C + DR +A+L+V LW TF+ + + S + A+ V
Sbjct: 855 LDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITV- 911
Query: 924 EFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWVIILAVLAGLLLLAVLVFVMY 980
+ KNL + D ST++ V + P + VP WVI+LAVLAGLL+LA+LV +++
Sbjct: 912 KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967
Query: 981 RMGFFKRVRPPQ 992
+MGFFKR + P+
Sbjct: 968 KMGFFKRAKHPE 979
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 248 bits (634), Expect = 2e-65
Identities = 287/1079 (26%), Positives = 461/1079 (42%), Gaps = 166/1079 (15%)
Query: 13 PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64
PR L+L L L + AFNLD + +G GS FG++V + R
Sbjct: 9 PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68
Query: 65 FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDP-LEFKSHQ 122
LL GAP+ G G V C ++ + D K+DP
Sbjct: 69 LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD------DCERMNITVKNDPGHHIIEDM 122
Query: 123 WFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTVE 168
W G +V S+ ++L CA Y W + + +R VG C+++ D +T
Sbjct: 123 WLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTYH 181
Query: 169 YAPCRSR-QLISDQVAEIVSKYD----------PNVYSIKYNNQLATRTAQAIFDDSY-- 215
C S + + ++ + P Y+ K N+ + R + + SY
Sbjct: 182 NEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKD 241
Query: 216 --------LGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIYD---GKNMSSLYNFT 262
+GY++ VG F + I V+G PR R +G V++ G ++
Sbjct: 242 PEDQGNLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVLE 299
Query: 263 GEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQ- 321
G Q+ AYFG ++A D+N D + D+ +GAP + +R K + G + V + +A F
Sbjct: 300 GSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGGAIYVFMNQAGTSFPA 355
Query: 322 --TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNA 379
+ L+G A FG ++A +GD++QDGF DIA+ AP+ G K VYI++ S GL
Sbjct: 356 HPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK---VYIYHSSSKGLLR 411
Query: 380 VPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVIT-VN 438
P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ D +L RARPVI V+
Sbjct: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-DHIVLLRARPVINIVH 470
Query: 439 AGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGVLPRKLNFQVELLLDK 495
L P++L+ P SC V C ++ G R + L D+
Sbjct: 471 KTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADR 522
Query: 496 LKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEY 555
++ +R F S S ++ M+C++L L D RDKL PI I M Y
Sbjct: 523 DRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD--NLRDKLRPIIISMNY 574
Query: 556 RLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDNVCKPKLEVS---VDS 606
L R GL+ PILNQ + +CG DN C+ L++ V
Sbjct: 575 SLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSE 634
Query: 607 DQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSIPLQADFIGVVRNNEA 656
Q+K+ Y D L L + N GE A+EA L + +P A + VR A
Sbjct: 635 QQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVP-PALLLSSVRPPGA 693
Query: 657 LARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNL 716
N+T + C+LGNP K ++ + F V + ++ LQ+ +S+
Sbjct: 694 C--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH 743
Query: 717 FDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKENPETEEDVGPVVQHI 773
D + P++ L +L ++ +S +H + +T EDVG +++
Sbjct: 744 QDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYE 798
Query: 774 YEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG----PMNCTSDMEINPLR 826
+++ G +L L+WPY+ +N LLY + G P D+ INPL
Sbjct: 799 FQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDL-INPLN 857
Query: 827 IKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVC 878
+ +S + + D GQG + A SE + T G A C+ + C
Sbjct: 858 LTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TVLTCATGRAHCVWLEC 916
Query: 879 QVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNS 938
+ D + VK+ +W TF+ + A+ F ++P ++ N
Sbjct: 917 PIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL----FLRTSIPTINMENK 970
Query: 939 TLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 989
T TW ++ P + +W++++AV AGLLLL +++ ++++ GFFKR R
Sbjct: 971 T------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 246 bits (627), Expect = 1e-64
Identities = 286/1079 (26%), Positives = 460/1079 (42%), Gaps = 166/1079 (15%)
Query: 13 PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64
PR L+L L L + AFNLD + +G GS FG++V + R
Sbjct: 9 PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68
Query: 65 FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDP-LEFKSHQ 122
LL GAP+ G G V C ++ + D K+DP
Sbjct: 69 LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD------DCERMNITVKNDPGHHIIEDM 122
Query: 123 WFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTVE 168
W G +V S+ ++L CA Y W + + +R VG C+++ D +T
Sbjct: 123 WLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTYH 181
Query: 169 YAPCRSR-QLISDQVAEIVSKYD----------PNVYSIKYNNQLATRTAQAIFDDSY-- 215
C S + + ++ + P Y+ K N+ + R + + SY
Sbjct: 182 NEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKD 241
Query: 216 --------LGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIYD---GKNMSSLYNFT 262
+GY++ VG F + I V+G PR R +G V++ G ++
Sbjct: 242 PEDQGNLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVLE 299
Query: 263 GEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQ- 321
G Q+ AYFG ++A D+N D + D+ +GAP + +R K + G + V + +A F
Sbjct: 300 GSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGGAIYVFMNQAGTSFPA 355
Query: 322 --TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNA 379
+ L+G A FG ++A +GD++QDGF DIA+ AP+ G K VYI++ S GL
Sbjct: 356 HPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK---VYIYHSSSKGLLR 411
Query: 380 VPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVIT-VN 438
P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ D +L RARPVI V+
Sbjct: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-DHIVLLRARPVINIVH 470
Query: 439 AGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGVLPRKLNFQVELLLDK 495
L P++L+ P SC V C ++ G R + L D+
Sbjct: 471 KTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADR 522
Query: 496 LKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEY 555
++ +R F S S ++ M+C++L L D RDKL PI I M Y
Sbjct: 523 DRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD--NLRDKLRPIIISMNY 574
Query: 556 RLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDNVCKPKLEVS---VDS 606
L R GL+ PILNQ + +CG DN C+ L++ V
Sbjct: 575 SLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSE 634
Query: 607 DQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSIPLQADFIGVVRNNEA 656
Q+K+ Y D L L + N GE A+EA L + +P A + VR A
Sbjct: 635 QQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVP-PALLLSSVRPPGA 693
Query: 657 LARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNL 716
N+T + C+LGNP K ++ + F V + ++ LQ+ +S+
Sbjct: 694 C--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH 743
Query: 717 FDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKENPETEEDVGPVVQHI 773
D + P++ L +L ++ +S +H + +T EDVG +++
Sbjct: 744 QDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYE 798
Query: 774 YEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG----PMNCTSDMEINPLR 826
+++ G +L L+WPY+ +N LLY + G P D+ INPL
Sbjct: 799 FQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDL-INPLN 857
Query: 827 IKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVC 878
+ +S + + D GQG + A SE + T G A C+ + C
Sbjct: 858 LTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TVLTCATGRAHCVWLEC 916
Query: 879 QVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNS 938
+ D + VK+ +W TF+ + A+ F ++P ++ N
Sbjct: 917 PIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL----FLRTSIPTINMENK 970
Query: 939 TLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 989
T TW ++ P + +W++++AV AGLLLL +++ ++++ FFKR R
Sbjct: 971 T------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTR 1023
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 240 bits (612), Expect = 6e-63
Identities = 273/1089 (25%), Positives = 474/1089 (43%), Gaps = 149/1089 (13%)
Query: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64
PR RL L L+++G+ A+NLD P + GP S+FG+AV +
Sbjct: 7 PRGAGRLRALLLALVVAGIP---AGAYNLDPQRPVHFQGPADSFFGYAV--LEHFHDNTR 61
Query: 65 FLLVGAPKANTT-QPGIVEGGQVLKC--DWSSTRRCQPIEFDATGNRDYAKDDPL-EFKS 120
++LVGAPKA++ P + G V KC + RRC ++ NR + E +
Sbjct: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121
Query: 121 HQWFGASV--RSKQD-KILACAPLYHWRTEMKQERE--PVGTCF-----LQDGTKTV--- 167
+W G S+ + K D ++LACA + W+ + P G C+ LQ +T+
Sbjct: 122 DEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPC 179
Query: 168 ----------EYAPCRSRQLISDQVAEIVSKYDPNVY----SIKYNNQLATRTAQAIFDD 213
E+ C++ + E+V P + +IK N L T + D+
Sbjct: 180 YEEYKKKYGEEHGSCQAG-IAGFFTEELVVMGAPGSFYWAGTIKVLN-LTDNTYLKLNDE 237
Query: 214 -------SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSS----LYNFT 262
+YLGY+V G F+ D V G P+ + +G VYI+ S ++ +
Sbjct: 238 VIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQD-KGIGKVYIFRADRRSGTLIKIFQAS 296
Query: 263 GEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQT 322
G++M +YFG S+ A D+NGD +D+ +GAP+F + +++ GQV+V + R +G +
Sbjct: 297 GKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSE------IRDEGQVTVYINRGNGALEE 350
Query: 323 T-KLNGFEVF-ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 380
L G + A FG +IA L DLD DGF D+AI AP +D G VYI++G + G+
Sbjct: 351 QLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAVYIYHGDAGGIVPQ 409
Query: 381 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 440
S L GQ + FG S+ G D+D NGYPD+ VGAF D +L RARPVITV+
Sbjct: 410 YSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVS 468
Query: 441 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 499
+ P +N C V+C NV C GK V P ++ L+ D K+K
Sbjct: 469 I-FLPGSINITAPQCH--DGQQPVNCLNVTTCFSFHGKHV-PGEIGLNYVLMADVAKKEK 524
Query: 500 GAIRRALFLYSRSPSHSKNMTISRGGLMQ-CEELIAYLRDESEFRDKLTPITIFMEYRLD 558
G + R F+ + + + C +A+++ +D ++PI Y L
Sbjct: 525 GQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVK--RRVQDVISPIVFEAAYSLS 582
Query: 559 YRTAA----DTTGLQPILNQFTPANISRQAHILL-------DCGEDNVCKPKLEVSVDSD 607
+ L P+L I+++ + DC D + KL +S D
Sbjct: 583 EHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLS-SMD 641
Query: 608 QKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFK 665
+K +Y +G ++L + N G+ AY+A + ++ + FI + + E +SC
Sbjct: 642 EKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEE--MGISCELL 699
Query: 666 TENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN------LFD 718
+ + C +G P M++ ++ + F S + + F + QS N L D
Sbjct: 700 ESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHD 756
Query: 719 KVSPV---VSHKVDLAVLAAVE----IRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQ 771
+ + H+VD ++ + + G S F+ + + E P +
Sbjct: 757 NTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQP---------IN 807
Query: 772 HIYELRNNGPSSFSKAMLHLQWPYKYNN-NTLLYILHYDIDGPMNCTSDMEINPLRIKIS 830
++ N GPS+ + + + +P + ++ ++ + + G + NP I
Sbjct: 808 ITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIP 867
Query: 831 SLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGC---GVAQCLKIVCQVGRLDRGK 887
E++++ ++ L C G++ CL C L + +
Sbjct: 868 Q--------------EQENIFHTIFAFFTKSGRKVLDCEKPGIS-CLTAHCNFSALAKEE 912
Query: 888 SAILYVKSLLWTETFMNKENQNHSY----SLKSSASFNVIEFPYKNLPIEDITNSTLVTT 943
S + + LL TE + + +K + V+E + N E++T V
Sbjct: 913 SRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGN--PEEVT----VVF 966
Query: 944 NVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPH 1003
++P V W+I +++L G+L+ +L ++++MGFF+R + +E ++
Sbjct: 967 EALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRR-------RYKEIIEAE 1018
Query: 1004 ENGEGNSET 1012
+N + N ++
Sbjct: 1019 KNRKENEDS 1027
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 193 bits (491), Expect = 6e-49
Identities = 211/842 (25%), Positives = 356/842 (42%), Gaps = 120/842 (14%)
Query: 192 NVYSIKYNNQLATRTAQAIFDDSYLGYSV-AVGDFNGDGIDDFVSGVPRAARTLGMVYIY 250
NV S K N LA SYLGY+V + +GD + +++G PR T G V IY
Sbjct: 422 NVESTKKNEPLA----------SYLGYTVNSATASSGDVL--YIAGQPRYNHT-GQVIIY 468
Query: 251 ---DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEV 306
DG N+ L +GEQ+ +YFG + TDI+ D D+ +GAP++M + +E
Sbjct: 469 RMEDG-NIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQ 523
Query: 307 GQVSV-SLQRASGDFQ-------------------TTKLNGFEVFARFGSAIAPLGDLDQ 346
G+V V +L + ++Q TT+ ARFG+AIA + DL+
Sbjct: 524 GKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNL 583
Query: 347 DGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGAT 406
DGFNDI I AP +D G VYI++G + +Q + +++ FG S+ G
Sbjct: 584 DGFNDIVIGAPLE-DDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLK-FFGQSIHGEM 641
Query: 407 DIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSC 466
D++ +G D+ +G G A L+ +R V V + P+ +N K C + G + C
Sbjct: 642 DLNGDGLTDVTIGGLG--GAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGK--ETVC 697
Query: 467 FNVRFC--LKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRG 524
N C +K K + + Q + LD L+Q I R+ F ++ +N+T+ +
Sbjct: 698 INATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS 754
Query: 525 GLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQA 584
+C + Y+ D+ +F+D + LD+ G P+L+ P ++
Sbjct: 755 ---ECTKHSFYMLDKHDFQDSV-------RITLDFNLTDPENG--PVLDDSLPNSVHEYI 802
Query: 585 HILLDCGEDNVCKPKLEVSVDSDQKKIYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIP 642
DCG C L + V + +K + I ++ + + +N + AY IV
Sbjct: 803 PFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYS 862
Query: 643 LQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEM 701
F G+ EA+ + SC + C +G P ++ G + + F + M
Sbjct: 863 PNLVFSGI----EAIQKDSC-----ESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM 913
Query: 702 DT-----SVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEH 756
+ S D + L D V V+ + + ++ +S HI + N
Sbjct: 914 ENVTIYLSATSDSEEPPETLSDNV---VNISIPVKYEVGLQFYSSASEYHISIAA-NETV 969
Query: 757 KENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMN 815
E + ED+G + Y +R +G + L + +P +N +LY N
Sbjct: 970 PEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENAN 1029
Query: 816 CTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLK 875
C + +P I TT DHL G I L C +
Sbjct: 1030 CRPHIFEDPFSINSGKKMTTST----------DHL--------KRGTI--LDCNTCKFAT 1069
Query: 876 IVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDI 935
I C + D + + V +LW TF+ + + +++ E +N +
Sbjct: 1070 ITCNLTSSDISQ---VNVSLILWKPTFIKSYFSSLNLTIRG-------ELRSENASLVLS 1119
Query: 936 TNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQ 995
+++ + P VP+WVI+L+ AGLLLL +L+ ++++GFFK RP +++
Sbjct: 1120 SSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFK--RPLKKKM 1177
Query: 996 ER 997
E+
Sbjct: 1178 EK 1179
Score = 49.3 bits (116), Expect = 2e-05
Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 14/145 (9%)
Query: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64
PR R R G L ++L C +FN+DV + +SGP FG+ V + +
Sbjct: 3 PRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWV 62
Query: 65 FL---LVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSH 121
+ LVG PK T G V KC ++ D N + E K +
Sbjct: 63 LIGSPLVGQPKNRT--------GDVYKCPVGRGESLPCVKLDLPVNTSI--PNVTEVKEN 112
Query: 122 QWFGAS-VRSKQDKILACAPLYHWR 145
FG++ V + LAC PLY +R
Sbjct: 113 MTFGSTLVTNPNGGFLACGPLYAYR 137
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 189 bits (481), Expect = 9e-48
Identities = 218/819 (26%), Positives = 360/819 (43%), Gaps = 106/819 (12%)
Query: 214 SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTGEQMAAYF 270
SYLGYSVA + FV+G PRA T G + +Y + N++ + G+Q+ +YF
Sbjct: 435 SYLGYSVAA--ISTGESTHFVAGAPRANYT-GQIVLYSVNENGNITVIQAHRGDQIGSYF 491
Query: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
G + + D++ D DV +GAP++M SD K +E G+V + + Q L G E
Sbjct: 492 GSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRVYLFTIKEGILGQHQFLEGPE 547
Query: 330 VF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQ-ILE 386
RFGSAIA L D++ DGFND+ + +P ++ G VYI+NG + SQ IL
Sbjct: 548 GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQN-SGAVYIYNGHQGTIRTKYSQKILG 606
Query: 387 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 446
A RS FG S+ G D++ + D+ +GAFG + + ++ + V P
Sbjct: 607 SDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEASFTPE 664
Query: 447 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKG----A 501
+ NK + LK+ CF+ +F P K N QV ++ + L G
Sbjct: 665 KITLVNKNAQI---ILKL-CFSAKF---------RPTKQNNQVAIVYNITLDADGFSSRV 711
Query: 502 IRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRT 561
R LF + KNM +++ C E I Y+++ S+ + L + R+D
Sbjct: 712 TSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPSDVVNSL-------DLRVD--I 760
Query: 562 AADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL-----EVSVDSDQKKIYIGDD 616
+ + G P L ++ DCGED +C L ++ +Q I +
Sbjct: 761 SLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQN 820
Query: 617 NPLTLIVKAQNQGEGAYEAELIVSIP---LQADFIGVVRNNEALARLSCAFKTENQTRQV 673
LT V +N+ E AY ++V A F V E +++ + K+ V
Sbjct: 821 KRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKS------V 874
Query: 674 VCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAV 732
CD+G P +K Q+ + F + Q+ + + + S +K +V+ K+ L
Sbjct: 875 ACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPL-- 932
Query: 733 LAAVEIRGVSSPDHIFLPIPNWEHKEN-PETEEDVGPVVQHIYELR---NNGPSSFSKAM 788
L EI S + F I + + + + EDVGP + I+ L+ + P S + +
Sbjct: 933 LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGP--KFIFSLKVTTGSVPVSMATVI 990
Query: 789 LHLQWPYKYNNNTLLYILHYDID--GPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 846
+H+ Y N L+Y+ D G ++C +D INPL+I +S + K++ E
Sbjct: 991 IHIP-QYTKEKNPLMYLTGVQTDKAGDISCNAD--INPLKIGQTSSSVSFKSENFRHTKE 1047
Query: 847 RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 906
L C A C + C + + + V + +W TF +
Sbjct: 1048 -------------------LNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASST 1088
Query: 907 NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 966
Q +++ +A+ + + + IED T VT + VP VII +++
Sbjct: 1089 FQ----TVQLTAAAEINTYNPEIYVIEDNT----VTIPLMIMKPDEKAEVPTGVIIGSII 1140
Query: 967 AGLLLLAVLVFVMYRMGFFKR-----VRPPQEEQEREQL 1000
AG+LLL LV +++++GFFKR + P E E +L
Sbjct: 1141 AGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTEL 1179
Score = 43.5 bits (101), Expect = 0.001
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 18/156 (11%)
Query: 10 RLGPRGLPLLL----SGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMF 65
R G LPLLL S +L C A+N+ + +SGP FG+AV F+ + +
Sbjct: 5 RTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGN--W 62
Query: 66 LLVGAPKANTTQPGIVEGGQVLKCDWS-STRRCQPIEFDATGNRDYAKDDPLEFKSHQWF 124
LLVG+P + + + G V KC ST C+ + + + + E K++
Sbjct: 63 LLVGSPWSGFPENRM---GDVYKCPVDLSTATCEKLNLQTS----TSIPNVTEMKTNMSL 115
Query: 125 GASVRSKQDK--ILACAPLYHWRTEMKQEREPVGTC 158
G + L C PL W + + G C
Sbjct: 116 GLILTRNMGTGGFLTCGPL--WAQQCGNQYYTTGVC 149
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 164 bits (416), Expect = 3e-40
Identities = 190/798 (23%), Positives = 340/798 (42%), Gaps = 84/798 (10%)
Query: 212 DDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQMAAY 269
+D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ AY
Sbjct: 400 NDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQIGAY 456
Query: 270 FGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKL-- 325
FG S+ + D++ + D V IGAP + ++ G QVSV L R +Q +
Sbjct: 457 FGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDAVLY 510
Query: 326 -NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQ 383
+ + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ
Sbjct: 511 GEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQ 569
Query: 384 ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEV 443
+ G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E
Sbjct: 570 RIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEF 626
Query: 444 YPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAI 502
P + ++ C+ K VR CL K R Q++ ++ L
Sbjct: 627 NPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGR 684
Query: 503 RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTA 562
+ +++ + + ++ T G CE L L + E D ++PI + + + L
Sbjct: 685 PHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPL 742
Query: 563 ADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTL 621
+ L+P+L + + +CG DN+C+ L ++ + +G +
Sbjct: 743 SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNV 802
Query: 622 IVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQV 673
V +N GE +Y ++ PL + + ++N + RL+C A TE +
Sbjct: 803 TVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKST 862
Query: 674 VCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVD 729
C + +P+ +++ + F V ++ + + + S N + + + V
Sbjct: 863 SCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVK 922
Query: 730 LAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 789
AV V GVS+ +L N E+ V+QH Y++ N G S +++
Sbjct: 923 YAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLV 970
Query: 790 HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDH 849
L P + N + D P Q T + + ++
Sbjct: 971 FLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKER 1003
Query: 850 LITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 909
L + D + C +A C +I C + + +K L + ++ K + N
Sbjct: 1004 LPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHN 1062
Query: 910 HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 969
H + S+A + + LP V + ++P +P P+ +I+ + + GL
Sbjct: 1063 H-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGL 1117
Query: 970 LLLAVLVFVMYRMGFFKR 987
LLLA++ +Y++GFFKR
Sbjct: 1118 LLLALITAALYKLGFFKR 1135
Score = 31.6 bits (70), Expect = 3.9
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)
Query: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84
L LC FNLD ++ + FG +V V SR ++VGAP+ + G
Sbjct: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61
Query: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143
+ +CD+ ST C+PI P+E + + ++LAC P H
Sbjct: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110
Query: 144 WRTEMKQEREPVGTCFL 160
+ G CFL
Sbjct: 111 --QTCSENTYVKGLCFL 125
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 163 bits (412), Expect = 9e-40
Identities = 186/794 (23%), Positives = 336/794 (42%), Gaps = 75/794 (9%)
Query: 212 DDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQMAAY 269
+D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ AY
Sbjct: 400 NDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQIGAY 456
Query: 270 FGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGF 328
FG S+ + D++ + D V IGAP + ++ G++ R D G
Sbjct: 457 FGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQG- 515
Query: 329 EVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQILEG 387
+ + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ + G
Sbjct: 516 QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQRIAG 574
Query: 388 QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI 447
+ + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E P
Sbjct: 575 SKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFNPRE 631
Query: 448 LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAIRRAL 506
+ ++ C+ K VR CL K R Q++ ++ L +
Sbjct: 632 VARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRPHSR 689
Query: 507 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 566
+++ + + ++ T G CE L L + E D ++PI + + + L +
Sbjct: 690 AVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPLSAFG 747
Query: 567 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKA 625
L+P+L + + +CG DN+C+ L ++ + +G + V
Sbjct: 748 NLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTV 807
Query: 626 QNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQVVCDL 677
+N GE +Y ++ PL + + ++N + RL+C A TE + C +
Sbjct: 808 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 867
Query: 678 GNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVDLAVL 733
+P+ +++ + F V ++ + + + S N + + + V AV
Sbjct: 868 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVY 927
Query: 734 AAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQW 793
V GVS+ +L N E+ V+QH Y++ N G S +++ L
Sbjct: 928 MVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLVFLV- 974
Query: 794 PYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITK 853
P + N + D P Q T + + ++ L +
Sbjct: 975 PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKERLPSH 1008
Query: 854 RDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 913
D + C +A C +I C + + +K L + ++ K + NH
Sbjct: 1009 SDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHNH-LL 1066
Query: 914 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 973
+ S+A + + LP V + ++P +P P+ +I+ + + GLLLLA
Sbjct: 1067 IVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLA 1122
Query: 974 VLVFVMYRMGFFKR 987
++ +Y++GFFKR
Sbjct: 1123 LITAALYKLGFFKR 1136
Score = 31.6 bits (70), Expect = 3.9
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)
Query: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84
L LC FNLD ++ + FG +V V SR ++VGAP+ + G
Sbjct: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61
Query: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143
+ +CD+ ST C+PI P+E + + ++LAC P H
Sbjct: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110
Query: 144 WRTEMKQEREPVGTCFL 160
+ G CFL
Sbjct: 111 --QTCSENTYVKGLCFL 125
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 161 bits (407), Expect = 3e-39
Identities = 193/823 (23%), Positives = 332/823 (40%), Gaps = 111/823 (13%)
Query: 214 SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNFTGEQMAAYF 270
+YLGY+V + G +V+G PR T G V ++ N SL G+Q+ +YF
Sbjct: 423 AYLGYTVTSVVSSRQG-RVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQAMRGQQIGSYF 480
Query: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
G + + DI+GD DV +GAP++ + G + V ++ +L +G T K +
Sbjct: 481 GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG---TLKDSHSY 537
Query: 330 VFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQW 389
ARFGS+IA + DL+QD +ND+ + AP ++ G +YIF+G + P Q +
Sbjct: 538 QNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGSILKTPKQRITASE 596
Query: 390 AARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILN 449
A + FG S+ G D++++G DL VGA G A++ +RPV+ +NA L PS +N
Sbjct: 597 LATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQINASLHFEPSKIN 653
Query: 450 QDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLY 509
++ C G +C C + P V + + + L
Sbjct: 654 IFHRDCKRSGR--DATCLAAFLCFTP--IFLAPHFQTTTVGIRYNATMDERRYTPRAHLD 709
Query: 510 SRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQ 569
+ + G CE + ++ D +++ + P+T +EY L +
Sbjct: 710 EGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKPVTFSVEYSL------EDPDHG 760
Query: 570 PILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD---------------------- 607
P+L+ P + C ED C P L + SD
Sbjct: 761 PMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAY 820
Query: 608 ----QKKIYIGDDNPLTLIVKA--QNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLS 661
++I + + V+A +N+GE AY L +S F +++ ++ +
Sbjct: 821 TLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIE 880
Query: 662 CAFKTENQTRQVVCDLGNPM---KAGTQLLAGLRFSVH---QQSEMDTSVKFDLQIQSSN 715
C E + ++ VC++ P KA FS E++ + D + S
Sbjct: 881 CV-NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDST 939
Query: 716 LFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE--EDVGPVVQHI 773
D V+P+ H L A V SS H +E K N E + +GP I
Sbjct: 940 KEDNVAPLRFH---LKYEADVLFTRSSSLSH-------YEVKPNSSLERYDGIGPPFSCI 989
Query: 774 YELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQ 833
+ ++N G M+ + P + L L + N + ++ N + + ++
Sbjct: 990 FRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE 1049
Query: 834 TTEKNDTVAGQGERDHLITKRDLAL---SEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAI 890
+ D + ++ L E + H LG + LK + + KS
Sbjct: 1050 EDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKAL-------KYKSMK 1102
Query: 891 LYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQ 950
+ V + L + Q HS + E P + + E ++ W
Sbjct: 1103 IMVNAAL--------QRQFHSPFIFRE------EDPSRQIVFE-------ISKQEDW--- 1138
Query: 951 PAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQE 993
VP+W+I+ + L GLLLLA+LV ++++GFF+ R +E
Sbjct: 1139 ----QVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRRE 1177
Score = 35.8 bits (81), Expect = 0.21
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 16/149 (10%)
Query: 13 PRGLPLLLSGLLLP-LCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP 71
PRGL + + L P FN+D P G ++FG+ V S +L+VGAP
Sbjct: 4 PRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQ--QHDISGNKWLVVGAP 61
Query: 72 KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS- 130
G + G V KC C + + E K + G S+ +
Sbjct: 62 LETN---GYQKTGDVYKCP-VIHGNCTKLNLGRV-----TLSNVSERKDNMRLGLSLATN 112
Query: 131 -KQDKILACAPLYHWRTEMKQEREPVGTC 158
K + LAC+PL W E G C
Sbjct: 113 PKDNSFLACSPL--WSHECGSSYYTTGMC 139
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 157 bits (398), Expect = 4e-38
Identities = 199/819 (24%), Positives = 332/819 (40%), Gaps = 92/819 (11%)
Query: 213 DSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAAYFG 271
DSYLGYS + + G + V G PR T +++ + TG Q+ +YFG
Sbjct: 402 DSYLGYSTELALWKG--VQSLVLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFG 459
Query: 272 FSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEV 330
S+ + D++ D D V IGAP + ++ G++ V + +R D G
Sbjct: 460 ASLCSVDVDSDGSTDLVLIGAPHYYEQTRGGQVS-VCPLPRGWRRWWCDAVLYGEQGHP- 517
Query: 331 FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNG-RSTGLNAVPSQILEGQW 389
+ RFG+A+ LGD++ D D+ I AP G E+ +G VY+F+G ++ SQ + G
Sbjct: 518 WGRFGAALTVLGDVNGDKLTDVVIGAP-GEEENRGAVYLFHGVLGPSISPSHSQRIAGSQ 576
Query: 390 AARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILN 449
+ S FG ++ G D+ ++G DL VGA G + +L R RPV+ V ++ P+ +
Sbjct: 577 LS-SRLQYFGQALSGGQDLTQDGLVDLAVGARG--QVLLLRTRPVLWVGVSMQFIPAEIP 633
Query: 450 QDNKTCSLPGTALKVSCFNVRFCLKAD--GKGVLPRKLNFQVELLLDKLKQKGAIR-RAL 506
+ C + + CL D K +L + + Q + LD G + RA
Sbjct: 634 RSAFECR-EQVVSEQTLVQSNICLYIDKRSKNLLGSR-DLQSSVTLDLALDPGRLSPRAT 691
Query: 507 FLYSRSPSHSKNMTISR----GGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTA 562
F +KN ++SR G CE L S D +TPIT+ + + L +
Sbjct: 692 F------QETKNRSLSRVRVLGLKAHCENFNLLL--PSCVEDSVTPITLRLNFTLVGKPL 743
Query: 563 ADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTL 621
L+P+L + +CG D++C+ L +S K + +G + L
Sbjct: 744 LAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNA 803
Query: 622 IVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNE----ALARLSC--AFKTENQTRQVVC 675
V N GE +Y + S P + V + L+C A T C
Sbjct: 804 EVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSC 863
Query: 676 DLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 734
+ + + + G Q+ F V ++ + + + S N + S + +++L V
Sbjct: 864 RINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK-TTFQLELPVKY 922
Query: 735 AVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWP 794
AV V S F N+ E+EE V H Y++ N G ++ P
Sbjct: 923 AVYT--VVSSHEQFTKYLNFS-----ESEEKESHVAMHRYQVNNLGQRDL-PVSINFWVP 974
Query: 795 YKYNNNTLLYILHYDIDGPMN----CTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHL 850
+ N + + ++ P N C+S+ P ++ +Q KN
Sbjct: 975 VELNQEAVW--MDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQ---KNP----------- 1018
Query: 851 ITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKEN 907
L C +A CL+ C V + +K L W + K+
Sbjct: 1019 --------------VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK- 1063
Query: 908 QNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLA 967
S+ S A Y LP ++ + T ++ + P +I+ + +
Sbjct: 1064 ----VSVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIG 1115
Query: 968 GLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1006
GLLLLA++ V+Y++GFFKR E+ Q+ P ENG
Sbjct: 1116 GLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 1153
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 149 bits (375), Expect = 2e-35
Identities = 139/484 (28%), Positives = 228/484 (47%), Gaps = 45/484 (9%)
Query: 214 SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNFTGEQMAAYF 270
+YLGYSV+ G G F+SG PR R G V + K ++ + GEQ+ +YF
Sbjct: 429 AYLGYSVSSMLLRG-GRRLFLSGAPRF-RHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYF 486
Query: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL--QRASGDFQTTKLNG 327
G + D + D DV + AP+F+ G K E G+V V L Q++ Q T
Sbjct: 487 GSELCPLDTDRDGTTDVLLVAAPMFL--GPQNK--ETGRVYVYLVGQQSLLTLQGTLQPE 542
Query: 328 FEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG 387
ARFG A+ L DL+QDGF D+A+ AP + +G +Y+++G +G+ P+Q +
Sbjct: 543 PPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHGTQSGVRPHPAQRI-- 599
Query: 388 QWAARSMPPS---FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444
AA SMP + FG S+ G D+D + D+ VGA G AIL +RP++ + LEV
Sbjct: 600 --AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSRPIVHLTPSLEVT 655
Query: 445 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL-LLDKLKQKGAIR 503
P ++ + C G + C C + + P + + Q + L + A
Sbjct: 656 PQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSR--TPGRWDHQFYMRFTASLDEWTAGA 711
Query: 504 RALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAA 563
RA F S + + +S G + CE+L ++ D S++ L P+ + + + LD
Sbjct: 712 RAAFDGSGQRLSPRRLRLSVGN-VTCEQLHFHVLDTSDY---LRPVALTVTFALD----- 762
Query: 564 DTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD----QKKIYI--GDDN 617
+TT P+LN+ +P +I + DCG DN C L + V+ D +K ++ G
Sbjct: 763 NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRR 822
Query: 618 PLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDL 677
+ + +N+ E AY L + + E+ ++ CA + + +C +
Sbjct: 823 KVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHAR---LCSV 879
Query: 678 GNPM 681
G+P+
Sbjct: 880 GHPV 883
Score = 65.1 bits (157), Expect = 3e-10
Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 872 QCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLP 931
QC + C +G+L +G + + L+ E F + KS + E +
Sbjct: 1044 QCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAK-------FKSLTVVSTFELGTEEGS 1096
Query: 932 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 991
+ +T ++ + ++ +Q P+ + +W++I +VL GLLLLA+LVF ++++GFF + P
Sbjct: 1097 VLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIP 1156
Query: 992 QEEQEREQLQ 1001
+EE+ E+L+
Sbjct: 1157 EEEKREEKLE 1166
Score = 35.0 bits (79), Expect = 0.36
Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 9/127 (7%)
Query: 16 LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANT 75
LPL+ L LC FNLD P + GP + FG++V V + ++LVGAP
Sbjct: 11 LPLVF---LTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHV--GGGQRWMLVGAP---W 62
Query: 76 TQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKI 135
P G V +C P G+ H
Sbjct: 63 DGPSGDRRGDVYRCPVGGAHNA-PCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGF 121
Query: 136 LACAPLY 142
+ACAPL+
Sbjct: 122 MACAPLW 128
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 146 bits (369), Expect = 8e-35
Identities = 134/470 (28%), Positives = 209/470 (44%), Gaps = 43/470 (9%)
Query: 189 YDPNVYSIKYNNQLATRTAQA-IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMV 247
YD ++ NQ A A A SYLGY+VAV + +++G PR +
Sbjct: 433 YDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYKHHGAVF 490
Query: 248 YIY-DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQE 305
+ +G+ S L GEQM +YFG + DI+ D D + + AP + G +G++
Sbjct: 491 ELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYV 550
Query: 306 VGQVSVSLQRASGDFQTTK-LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAP---YG 359
L G F + L+G F ARFG A+A +GDL QD D+AI AP +G
Sbjct: 551 Y-----RLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFG 605
Query: 360 GED--KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLI 417
+D G VYI+NG GL+A PSQ + A + FG SM G DI +G D+
Sbjct: 606 ADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGL-QYFGMSMAGGFDISGDGLADIT 664
Query: 418 VGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADG 477
VG G +A+++R+RPV+ + + PS L G CF + A
Sbjct: 665 VGTLG--QAVVFRSRPVVRLKVSMAFTPSAL-----PIGFNGVVNVRLCFEISSVTTASE 717
Query: 478 KGVLPRKLNFQVELLLDKLKQK---GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIA 534
G+ LNF +++ + K +++ +R L S G CE+L+
Sbjct: 718 SGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSS----------GSQLCEDLL- 766
Query: 535 YLRDESEF--RDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGE 592
+ E E D + ++ + Y+L T QPIL+++T Q C
Sbjct: 767 LMPTEGELCEEDCFSNASVKVSYQLQ-TPEGQTDHPQPILDRYTEPFAIFQLPYEKACKN 825
Query: 593 DNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIP 642
C +L+++ Q+++ +G LTL + N GE +Y + ++ P
Sbjct: 826 KLFCVAELQLATTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875
Score = 31.2 bits (69), Expect = 5.2
Identities = 12/28 (42%), Positives = 21/28 (75%)
Query: 960 VIILAVLAGLLLLAVLVFVMYRMGFFKR 987
+II + GLL+L V++ ++++ GFFKR
Sbjct: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 139 bits (349), Expect = 2e-32
Identities = 188/799 (23%), Positives = 336/799 (42%), Gaps = 93/799 (11%)
Query: 213 DSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAAYFG 271
DSYLGYS + + G + + V G PR T +++ + TG Q+ +YFG
Sbjct: 401 DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFG 458
Query: 272 FSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKLNGFE 329
S+ + D++ D D + IGAP + ++ G QVSV L R +Q + E
Sbjct: 459 ASLCSVDVDSDGSTDLILIGAPHYYEQTRGG------QVSVCPLPRGRVQWQCDAVLRGE 512
Query: 330 V---FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQ-I 384
+ RFG+A+ LGD+++D D+AI AP G ++ +G VY+F+G S +G++ SQ I
Sbjct: 513 QGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISPSHSQRI 571
Query: 385 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444
Q + R FG ++ G D+ ++G DL VGA G + +L R+ PV+ V +
Sbjct: 572 ASSQLSPRLQ--YFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVLKVGVAMRFS 627
Query: 445 PSILNQDNKTC-SLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAI- 502
P + + C +AL+ + CL K L + + Q + D G +
Sbjct: 628 PVEVAKAVYRCWEEKPSALEAG--DATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPGRLT 684
Query: 503 RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTA 562
RA+F +++P+ ++ T+ G + CE L L D E D ++PI + + + L
Sbjct: 685 SRAIFNETKNPTLTRRKTLGLG--IHCETLKLLLPDCVE--DVVSPIILHLNFSLVREPI 740
Query: 563 ADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTL 621
L+P+L + + +CG+D +C+ L V++ S + + +G L +
Sbjct: 741 PSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLELNV 800
Query: 622 IVKAQNQGEGAYEAELIVSIPLQADFIGV----VRNNEALARLSC-AFKTENQ-TRQVVC 675
IV N GE +Y + + P V + +++ RL+C TE++ R C
Sbjct: 801 IVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRC 860
Query: 676 DLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAA 735
+ +P+ H+ S V FD+ +++ + ++ + A+
Sbjct: 861 SVNHPI-------------FHEGSNGTFIVTFDVSYKAT---------LGDRMLMRASAS 898
Query: 736 VEIRGVSSPDHIF---LPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQ 792
E SS F LP+ + EE N +S K M +
Sbjct: 899 SENNKASSSKATFQLELPVKYAVYTMISRQEESTKYF---------NFATSDEKKMKEAE 949
Query: 793 WPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKN-DTVAGQGERDHLI 851
Y+ NN + D+ +N + +N + + ++ ++ V+ + H
Sbjct: 950 HRYRVNN-----LSQRDLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQH-- 1002
Query: 852 TKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQ 908
D L C +A CL+ C V + +K L W + K+
Sbjct: 1003 --SDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKK-- 1058
Query: 909 NHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAG 968
+ S A Y LP ++ + + ++ + + +I+ + +
Sbjct: 1059 ---VLVVSVAEITFDTSVYSQLPGQE----AFMRAQMEMVLEEDEVYNAIPIIMGSSVGA 1111
Query: 969 LLLLAVLVFVMYRMGFFKR 987
LLLLA++ +Y++GFFKR
Sbjct: 1112 LLLLALITATLYKLGFFKR 1130
Score = 32.3 bits (72), Expect = 2.3
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 29/133 (21%)
Query: 15 GLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP--- 71
G LLLS +L FNLDV+ P + G + V F SR L+VGAP
Sbjct: 4 GTVLLLS--VLASYHGFNLDVEEPTIFQEDAGGFGQSVVQF----GGSR--LVVGAPLEV 55
Query: 72 -KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS 130
AN T G++ C ++T CQPI + + + + AS
Sbjct: 56 VAANQT-------GRLYDCA-AATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNG 100
Query: 131 KQDKILACAPLYH 143
++LAC P H
Sbjct: 101 --SRLLACGPTLH 111
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 120 bits (302), Expect = 5e-27
Identities = 139/526 (26%), Positives = 227/526 (43%), Gaps = 52/526 (9%)
Query: 215 YLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKNMSSLYNFTGEQMAAYF 270
YLGY+V + SG PR +G V ++ G + S + G Q+ +YF
Sbjct: 320 YLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYF 377
Query: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
G + D++ D ++ IGAPLF Q G+V + +R G + ++L G
Sbjct: 378 GGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQRRQLGFEEVSELQGDP 431
Query: 330 VF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG 387
+ RFG AI L D++ DG D+A+ AP +++G VYIFNGR GL+ PSQ +EG
Sbjct: 432 GYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQPSQRIEG 488
Query: 388 QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI 447
+ FG S+ G D++ +G D+ VGA + I+ +RPV+ + + P+
Sbjct: 489 TQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAE 545
Query: 448 LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG--AIRRA 505
+ CS + N+ C + K ++P+ V L L+ G RR
Sbjct: 546 IPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVANLTYTLQLDGHRTRRRG 603
Query: 506 LFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRL-------- 557
LF R H I+ M C + + +D ++PI + + + L
Sbjct: 604 LFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPINVSLNFSLWEEEGTPR 658
Query: 558 DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPKLEVSVD-SDQKKIYIG 614
D R D + PIL P+ S I + CGED C+ L VS + + + +
Sbjct: 659 DQRAGKD---IPPILR---PSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLT 712
Query: 615 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEALARLSCAFKTENQ---T 670
L++ + N E AY +L + P F V + + +SC E +
Sbjct: 713 AFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLS 772
Query: 671 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN 715
R + C++ +P+ KAG + + F+ S SV+ + +N
Sbjct: 773 RALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNN 818
Score = 34.3 bits (77), Expect = 0.61
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 958 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 987
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 119 bits (298), Expect = 1e-26
Identities = 139/526 (26%), Positives = 227/526 (43%), Gaps = 51/526 (9%)
Query: 215 YLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKNMSSLYNFTGEQMAAYF 270
YLGY+V + SG PR +G V ++ G + S + G Q+ +YF
Sbjct: 403 YLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYF 460
Query: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
G + D++ D ++ IGAPLF Q G+V + +R G + ++L G
Sbjct: 461 GGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQRRQLGFEEVSELQGDP 514
Query: 330 VF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG 387
+ RFG AI L D++ DG D+A+ AP +++G VYIFNGR GL+ PSQ +EG
Sbjct: 515 GYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQPSQRIEG 571
Query: 388 QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI 447
+ FG S+ G D++ +G D+ VGA + I+ +RPV+ + + P+
Sbjct: 572 TQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAE 628
Query: 448 LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG--AIRRA 505
+ CS + N+ C + K ++P+ V L L+ G RR
Sbjct: 629 IPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVANLTYTLQLDGHRTRRRG 686
Query: 506 LFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRL-------- 557
LF R H I+ M C + + +D ++PI + + + L
Sbjct: 687 LFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPINVSLNFSLWEEEGTPR 741
Query: 558 DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPKLEVSVD-SDQKKIYIG 614
D R A + PIL P+ S I + CGED C+ L VS + + + +
Sbjct: 742 DQR--AQGKDIPPILR---PSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLT 796
Query: 615 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEALARLSCAFKTENQ---T 670
L++ + N E AY +L + P F V + + +SC E +
Sbjct: 797 AFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLS 856
Query: 671 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN 715
R + C++ +P+ KAG + + F+ S SV+ + +N
Sbjct: 857 RALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNN 902
Score = 34.3 bits (77), Expect = 0.61
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 958 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 987
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 61.6 bits (148), Expect = 4e-09
Identities = 55/221 (24%), Positives = 104/221 (47%), Gaps = 29/221 (13%)
Query: 217 GYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYF------ 270
G +V + D + + R RT+ G +S + +A+YF
Sbjct: 326 GVFFSVNSWTPDSMSFIYKALERNIRTM----FIGGSQLSQKH--VSSPLASYFLSFPYA 379
Query: 271 --GFSVAATDINGDDYADVFIGAPLFMDRG--SDGKLQEVGQVSVSLQRASGDFQTTK-- 324
G+++ + D+N D + D+ +GAP + G G++ + + L D
Sbjct: 380 RLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHR 439
Query: 325 -LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDK---KGIVYI-FNGRSTGLNA 379
L GF+ RFGSA+A L D + DG D+A+ AP G ++ KG VY+ F + G+++
Sbjct: 440 ILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSS 498
Query: 380 VPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 420
P+ + + + + + G+++ A D++ + PDL++G+
Sbjct: 499 SPNITI----SCQDIYCNLGWTLL-AADVNGDSEPDLVIGS 534
Score = 55.1 bits (131), Expect = 3e-07
Identities = 56/218 (25%), Positives = 91/218 (41%), Gaps = 27/218 (12%)
Query: 211 FDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART----LGMVYIYDGKNM----------- 255
F + LG+++ D N DG D V G P +R +G VY+ G ++
Sbjct: 376 FPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDK 435
Query: 256 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 315
+ G Q + FG ++A D N D D+ +GAP GS+ +L G V V
Sbjct: 436 EAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAP---SVGSE-QLTYKGAVYVYFGS 491
Query: 316 ASGDFQTT---KLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPY--GGEDKKGIVYIF 370
G ++ ++ +++ G + D++ D D+ I +P+ GG +KGIV F
Sbjct: 492 KQGGMSSSPNITISCQDIYCNLGWTLL-AADVNGDSEPDLVIGSPFAPGGGKQKGIVAAF 550
Query: 371 NGRSTGLNAVPSQILEGQWAARSMPPS--FGYSMKGAT 406
+ + + W R FGYS+ G T
Sbjct: 551 YSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHGVT 588
Score = 55.1 bits (131), Expect = 3e-07
Identities = 48/159 (30%), Positives = 77/159 (48%), Gaps = 32/159 (20%)
Query: 242 RTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDI--NGDDYADVFIGAPLFMDRGS 299
++LG VY Y N S + +G++ G S+++ + NG + +GAP + D
Sbjct: 619 KSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYDD--- 675
Query: 300 DGKLQEVGQVSVSLQRA--------SGDFQTTKLNGFEV---FARFGSAIAPLGDLDQDG 348
+ +V ++V+L + + D Q L+ F F+RFG + L DLD DG
Sbjct: 676 ---VSKVAFLTVTLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVLH-LSDLDDDG 731
Query: 349 FNDIAIAAP----------YGGEDKKGIVYIFNGRSTGL 377
++I +AAP GGED G VY++NG+ T L
Sbjct: 732 LDEIIMAAPLRIADVTSGLIGGED--GRVYVYNGKETTL 768
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 203 ATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTL----GMVYIYDGKN---M 255
A R + G ++AV DFN DG+ D G P G VY+Y G M
Sbjct: 437 AHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGM 496
Query: 256 SSLYNFTGEQMAAY--FGFSVAATDINGDDYADVFIGAP 292
SS N T Y G+++ A D+NGD D+ IG+P
Sbjct: 497 SSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSP 535
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 50.4 bits (119), Expect = 8e-06
Identities = 92/454 (20%), Positives = 168/454 (37%), Gaps = 56/454 (12%)
Query: 589 DCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADF 647
+CG D++C+ L +S K + +G + L V N GE +Y + S P +
Sbjct: 19 NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78
Query: 648 IGVVRNNEA----LARLSC--AFKTENQTRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSE 700
V + L+C A T C + + + + G Q+ F V ++
Sbjct: 79 RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138
Query: 701 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 760
+ + + S N + S + +++L V AV V S F N+
Sbjct: 139 LGDRLLLTANVSSENNTPRTSKT-TFQLELPVKYAVYT--VVSSHEQFTKYLNFS----- 190
Query: 761 ETEEDVGPVVQHIYELRNNGPSSFS----------KAMLHLQWPYKYNNNTL-------- 802
E+EE V H Y+ ++ ++ P + N +
Sbjct: 191 ESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSH 250
Query: 803 -------LYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRD 855
+++LH + ++ M + + + L +N ++ E+
Sbjct: 251 PQVPKDCMWLLH-ECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF 309
Query: 856 LALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQNHSY 912
LA + + L C +A CL+ C V + +K L W + K+
Sbjct: 310 LAHIQKN-PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK-----V 363
Query: 913 SLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLL 972
S+ S A Y LP ++ + T ++ + P +I+ + + GLLLL
Sbjct: 364 SVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 419
Query: 973 AVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1006
A++ V+Y++GFFKR E+ Q+ P ENG
Sbjct: 420 ALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 452
>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform b [Homo sapiens]
Length = 1143
Score = 31.6 bits (70), Expect = 3.9
Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 4/80 (5%)
Query: 126 ASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISDQVAEI 185
AS R+ QD+ C P H + + E + + DG V ++ DQV
Sbjct: 852 ASNRTHQDQPQKCGPNSHCEMDCEVNNEDLLCVLIDDGGFLV----LSNQNHQWDQVGRF 907
Query: 186 VSKYDPNVYSIKYNNQLATR 205
S+ D N+ YNN TR
Sbjct: 908 FSEVDANLMLALYNNSFYTR 927
>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform a [Homo sapiens]
Length = 1145
Score = 31.6 bits (70), Expect = 3.9
Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 4/80 (5%)
Query: 126 ASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISDQVAEI 185
AS R+ QD+ C P H + + E + + DG V ++ DQV
Sbjct: 852 ASNRTHQDQPQKCGPNSHCEMDCEVNNEDLLCVLIDDGGFLV----LSNQNHQWDQVGRF 907
Query: 186 VSKYDPNVYSIKYNNQLATR 205
S+ D N+ YNN TR
Sbjct: 908 FSEVDANLMLALYNNSFYTR 927
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,817,201
Number of Sequences: 37866
Number of extensions: 1792685
Number of successful extensions: 3926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 3545
Number of HSP's gapped (non-prelim): 80
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.