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Search of human proteins with 223029430
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223029430 solute carrier family 2 (facilitated glucose transp... 879 0.0
gi|223029432 solute carrier family 2 (facilitated glucose transp... 733 0.0
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 306 2e-83
gi|4507011 glucose transporter 4 [Homo sapiens] 155 9e-38
gi|166795299 solute carrier family 2 (facilitated glucose transp... 150 2e-36
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 140 2e-33
gi|23592238 glucose transporter 14 [Homo sapiens] 140 2e-33
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 136 4e-32
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 128 9e-30
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 127 2e-29
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 124 1e-28
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 124 2e-28
gi|203098995 solute carrier family 2 (facilitated glucose transp... 121 1e-27
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 117 3e-26
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 117 3e-26
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 117 3e-26
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 91 2e-18
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 90 5e-18
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 72 8e-13
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 67 4e-11
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 66 6e-11
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 62 1e-09
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 60 5e-09
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 60 5e-09
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 59 7e-09
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 58 2e-08
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 58 2e-08
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 52 8e-07
gi|24308167 SV2 related protein [Homo sapiens] 51 2e-06
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 49 7e-06
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 879 bits (2270), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS
Sbjct: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
Query: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA
Sbjct: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
Query: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG
Sbjct: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
Query: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT
Sbjct: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
Query: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS
Sbjct: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
Query: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSGYAVGWGPITWLLMS 360
IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSGYAVGWGPITWLLMS
Sbjct: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSGYAVGWGPITWLLMS 360
Query: 361 EVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCC 420
EVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCC
Sbjct: 361 EVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCC 420
Query: 421 VPETKGRSLEQIESFFRTGRRSFLR 445
VPETKGRSLEQIESFFRTGRRSFLR
Sbjct: 421 VPETKGRSLEQIESFFRTGRRSFLR 445
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 733 bits (1891), Expect = 0.0
Identities = 407/507 (80%), Positives = 418/507 (82%), Gaps = 62/507 (12%)
Query: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS
Sbjct: 1 MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTS 60
Query: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA
Sbjct: 61 PVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSA 120
Query: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG
Sbjct: 121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFG 180
Query: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT
Sbjct: 181 SLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
Query: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS
Sbjct: 241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQS 300
Query: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS-----------GYAV 349
IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS G +
Sbjct: 301 IFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYI 360
Query: 350 GWGP------ITWLLMSE-----VLPLRA-RGVASGLCVLASWL-----------TAFVL 386
+GP T L SE PL A G + + +LA+ L ++L
Sbjct: 361 HFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLL 420
Query: 387 TKSFLPV---------------VSTFGLQVPF------------FF-FAAICLVSLVFTG 418
LP+ ++ F L F FF FAAICLVSLVFTG
Sbjct: 421 MSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTG 480
Query: 419 CCVPETKGRSLEQIESFFRTGRRSFLR 445
CCVPETKGRSLEQIESFFRTGRRSFLR
Sbjct: 481 CCVPETKGRSLEQIESFFRTGRRSFLR 507
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 306 bits (785), Expect = 2e-83
Identities = 191/481 (39%), Positives = 266/481 (55%), Gaps = 73/481 (15%)
Query: 17 PEKPPP---SPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPD 73
PE+ P PG A G +RVFLA FAA LG SFG+AL Y+SP IP+L+R+ P
Sbjct: 6 PEETQPLLGPPGGSAPRG----RRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPA 61
Query: 74 LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW 133
L + ASWFG+V TLGAAAGG+ L D GRKLS++ +VP AG+A++ A +W
Sbjct: 62 PRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVW 121
Query: 134 MLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPW 193
MLL GR LTG A G+ + PVY+SEIA P VRG LG+ QLM V G L Y G +L W
Sbjct: 122 MLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEW 181
Query: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253
RWLAV G P +M+LL+ FMP +PRFLL++ R +EA+ AL +L G++ WE I
Sbjct: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQG--WEDPPIG- 238
Query: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKD 313
QS + A R P + +P + + + QQL+G+ ++ Y ++IF+ A
Sbjct: 239 --AEQSFHL--ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEE-AKFKDSSL 293
Query: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSGYAVGW--------------GP------ 353
+ +VG +++L +AAL MD AGR++LL +SG + + GP
Sbjct: 294 ASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHV 353
Query: 354 ----------------ITWL----------------------LMSEVLPLRARGVASGLC 375
+ WL LMSE+ PL +GVA+G+C
Sbjct: 354 AISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGIC 413
Query: 376 VLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESF 435
VL +WL AF++TK F ++ F+ +A C+ S++FT CVPETKG++LEQI +
Sbjct: 414 VLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAH 473
Query: 436 F 436
F
Sbjct: 474 F 474
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 155 bits (391), Expect = 9e-38
Identities = 135/462 (29%), Positives = 210/462 (45%), Gaps = 69/462 (14%)
Query: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLD---------------PDLHLTKSQASWF 84
LA F+AVLG+ FGY + + +E+S + P LT A
Sbjct: 26 LAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSV 85
Query: 85 GSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTL 141
++F++G I++ LGRK +++ + V + G +LM A ML+LGR L
Sbjct: 86 -AIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFL 144
Query: 142 TGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRW 195
G GLT+ +P+YV EIAP +RGALG QL V G L LGL LL W
Sbjct: 145 IGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPL 204
Query: 196 LAVAGEAPVLIMILLLSFMPNSPRFL-LSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN 254
L P L+ ++LL F P SPR+L + + + A ++L L G DV +++D
Sbjct: 205 LLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGW-ADVSGVLAELKDE 263
Query: 255 VRR--QSSRVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPP 311
R+ + +S + R P+ +A++++L QQL+GI + Y SIF++ V P
Sbjct: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPA 323
Query: 312 KDDAAIVGAVRLLSVLIAALTMDLAGRKVLL----------------------------- 342
G V + L++ L ++ AGR+ L
Sbjct: 324 YATIG-AGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSY 382
Query: 343 --------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVV 394
FV+ + +G GPI W +++E+ R A + ++W + F++ F V
Sbjct: 383 VSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVA 442
Query: 395 STFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
G V F FA + L +FT VPET+GR+ +QI + F
Sbjct: 443 EAMGPYV-FLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 150 bits (379), Expect = 2e-36
Identities = 134/470 (28%), Positives = 209/470 (44%), Gaps = 71/470 (15%)
Query: 37 RVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDP------------DLHLTKSQASWF 84
R+ LA AVLG+ FGY + VI A ++ ++ + T W
Sbjct: 11 RLMLAVGGAVLGSLQFGY----NTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWS 66
Query: 85 GSV--FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAH---GLWMLLLGR 139
SV F++G G S + + GR+ S++ + + LM + ML+LGR
Sbjct: 67 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGR 126
Query: 140 TLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL------LLPW 193
+ G GLT +P+YV E++P +RGALG QL V G L GL W
Sbjct: 127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLW 186
Query: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQ 252
L P L+ ++L F P SPRFLL +R + A L LRGT DV + ++++
Sbjct: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT-ADVTHDLQEMK 245
Query: 253 DNVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLL 309
+ R+ + +V+ E R+P +PI +A++++L QQL+GI + Y SIF+ V
Sbjct: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ 305
Query: 310 PPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLL--------------------------- 342
P G V +++ ++ AGR+ L
Sbjct: 306 PVYATIG-SGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWM 364
Query: 343 ----------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLP 392
FV+ + VG GPI W +++E+ R A + ++W + F++ F
Sbjct: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
Query: 393 VVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRS 442
V G V F F + ++ +FT VPETKGR+ ++I S FR G S
Sbjct: 425 VEQLCGPYV-FIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGAS 473
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 140 bits (353), Expect = 2e-33
Identities = 121/400 (30%), Positives = 185/400 (46%), Gaps = 59/400 (14%)
Query: 93 AAGGLSAMI----LNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW----MLLLGRTLTGF 144
A GG++A L D LGR +++ + + S G AL+ G L +++ GR+++G
Sbjct: 105 AVGGMTASFFGGWLGDTLGRIKAMLVANILSLVG-ALLMGFSKLGPSHILIIAGRSISGL 163
Query: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP------WRWLAV 198
GL + +P+Y+ EIAP +RGALG QL V G L +GL W L
Sbjct: 164 YCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLG 223
Query: 199 AGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQIQDNVRR 257
++ LLL F P SPR+L + +E +A ++L LRG D DV + +++
Sbjct: 224 LSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYD-DVTKDINEMRKEREE 282
Query: 258 QSS--RVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
SS +VS + R PI VAL++ + QQ +GI I Y SIF TA + P
Sbjct: 283 ASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ-TAGISKPVYA 341
Query: 315 AAIVGAVRLLSVLIAALTMDLAGRK----------------------------------- 339
VGAV ++ ++ ++ AGR+
Sbjct: 342 TIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSM 401
Query: 340 --VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTF 397
+ LFVS + +G GPI W +++E R A + ++W F++ F +
Sbjct: 402 IAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFC 461
Query: 398 GLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFR 437
G V FF FA + L +FT VPETKG+S E+I + F+
Sbjct: 462 GPYV-FFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQ 500
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 140 bits (353), Expect = 2e-33
Identities = 125/459 (27%), Positives = 203/459 (44%), Gaps = 63/459 (13%)
Query: 38 VFLATFAAVLGNFSFGYAL-VYTSP---VIPALERSLDPDLHLTKSQA------SWFGSV 87
+ A A +G+F FGY V +P + + ++L + S+ S ++
Sbjct: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93
Query: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLTGF 144
F++G G S + + GR+ S++ + +A G LM A + ML+LGR + G
Sbjct: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153
Query: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WRWLAV 198
GL +P+Y+ EI+P +RGA G QL V G L ++ L L+L W L
Sbjct: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213
Query: 199 AGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRR 257
P ++ L P SPRFLL +R ++E A R L L GT DV + ++++D R
Sbjct: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQ-DVSQDIQEMKDESAR 272
Query: 258 --QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYAT 332
Query: 315 AAIVGAVRLLSVLIAALTMDLAGRK----------------------------------- 339
+ G V + L++ ++ AGR+
Sbjct: 333 IS-AGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCI 391
Query: 340 --VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTF 397
+L+FV+ + +G GPI W +++E+ R A + ++W + F++ F
Sbjct: 392 GAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYL 451
Query: 398 GLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
G V F F + L FT VPET+GR+ E I F
Sbjct: 452 GAYV-FIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 136 bits (342), Expect = 4e-32
Identities = 124/463 (26%), Positives = 198/463 (42%), Gaps = 71/463 (15%)
Query: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLD--------------PDLHLTKSQASW 83
+ A A +G+F FGY + VI A E+ + P L S S
Sbjct: 10 LIFAITVATIGSFQFGY----NTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSL 65
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRT 140
++F++G G S + + GR+ S++ + + G M A + ML+LGR
Sbjct: 66 SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRL 125
Query: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WR 194
+ G GL +P+Y+ EI+P +RGA G QL V G L ++ L +L W
Sbjct: 126 VIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWP 185
Query: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253
L P ++ L F P SPRFLL +R +E A + L L GT DV + ++++D
Sbjct: 186 LLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQ-DVSQDIQEMKD 244
Query: 254 NVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
R Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 245 ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP 304
Query: 311 PKDDAAIVGAVRLLSVLIAALTMDLAGRK------------------------------- 339
G V + +++ ++ AGR+
Sbjct: 305 IYATIG-AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMS 363
Query: 340 ------VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPV 393
+L+FV+ + +G GPI W +++E+ R A + ++W + F++ F
Sbjct: 364 FVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 423
Query: 394 VSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
G V F F + L FT VPET+GR+ E I F
Sbjct: 424 AHYLGAYV-FIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 128 bits (322), Expect = 9e-30
Identities = 126/486 (25%), Positives = 218/486 (44%), Gaps = 72/486 (14%)
Query: 20 PPPSPGDRARVGTLQNKRVFLATFAAVLGN-FSFGYAL-VYTSP--VIPALERSLDPDLH 75
PPP P +R G LQ + LAT +A G+ F +GY L V +P V + + H
Sbjct: 9 PPPIP---SREGRLQ-PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERH 64
Query: 76 LTKSQA-------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM----FSAVPSAA-GY 123
T S S+F LG G L +L D GRK +++ F+ +P+ G
Sbjct: 65 ATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGV 124
Query: 124 ALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL- 182
+ +A A L ++ R + G G++ + +P+Y+ E+AP +RG +G ++ + G
Sbjct: 125 SKVAKAFEL--IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFL 182
Query: 183 -SLYALGLLL--PWRW---LAVAGEAPVLIMILLLSFMPNSPRF-LLSRGRDEEALRALA 235
+++L +L P W LA+ G P L+ +L L F P SPR+ L+ +G + A +AL
Sbjct: 183 AQIFSLQAILGNPAGWPVLLALTG-VPALLQLLTLPFFPESPRYSLIQKGDEATARQALR 241
Query: 236 WLRG-TDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLL-QQLTGITP 293
LRG TD++ E + + R +S A R +++++ + QQL+GI
Sbjct: 242 RLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINA 301
Query: 294 ILVYLQSIFDSTAVLLPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL---------- 342
I Y +I+ S V + G V ++ + +A+ ++ GR+ LL
Sbjct: 302 INYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSA 361
Query: 343 ---------------------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLC 375
+++G+++G P+ ++ +E+ +R A +
Sbjct: 362 CLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVD 421
Query: 376 VLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESF 435
WLT F++ F + G F FA ICL++ ++ +PETKG++ +I
Sbjct: 422 GAVHWLTNFIIGFLFPSIQEAIG-AYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI 480
Query: 436 FRTGRR 441
F R
Sbjct: 481 FAKRNR 486
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 127 bits (320), Expect = 2e-29
Identities = 128/503 (25%), Positives = 210/503 (41%), Gaps = 87/503 (17%)
Query: 21 PPSPG------DRARVGTLQNKR-------VFLATFAAVLGN-FSFGYALVYTSPVIPAL 66
PP PG D R G +R + +A+ A G+ F +GY L + P +
Sbjct: 26 PPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYI 85
Query: 67 E------------RSLDPD-LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM 113
+ R +DPD L L S S+F +G G L ++ +LGRK +++
Sbjct: 86 KAFYNESWERRHGRPIDPDTLTLLWSVTV---SIFAIGGLVGTLIVKMIGKVLGRKHTLL 142
Query: 114 FS---AVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALG 170
+ A+ +A A A ML++GR + G GG+ + +P+Y+SEI+P +RG+LG
Sbjct: 143 ANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLG 202
Query: 171 ATPQLMAVFGSLSLYALGL--LL----PWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSR 224
+ G + LGL LL W +L P ++ +L L F+P+SPR+LL
Sbjct: 203 QVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLE 262
Query: 225 GRDE-EALRALAWLRGTDVDVHWEFEQI--QDNVRRQSSRVSWAE-ARAPHVCRPITVAL 280
+E A++A G DV E E++ + V+R VS E RAP+V + +
Sbjct: 263 KHNEARAVKAFQTFLG-KADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVI 321
Query: 281 LMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI---VGAVRLLSVLIAALTMDLAG 337
+ QL G+ I Y SIF + PP + G + L+ + + L ++ G
Sbjct: 322 VTMACYQLCGLNAIWFYTNSIFGKAGI--PPAKIPYVTLSTGGIETLAAVFSGLVIEHLG 379
Query: 338 RK-------------------------------------VLLFVSGYAVGWGPITWLLMS 360
R+ +L ++ + G G I ++L
Sbjct: 380 RRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTG 439
Query: 361 EVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCC 420
E R A + +WL+ F + F P + F FA IC+ ++
Sbjct: 440 EFFQQSQRPAAFIIAGTVNWLSNFAVGLLF-PFIQKSLDTYCFLVFATICITGAIYLYFV 498
Query: 421 VPETKGRSLEQIESFFRTGRRSF 443
+PETK R+ +I F +++
Sbjct: 499 LPETKNRTYAEISQAFSKRNKAY 521
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 124 bits (312), Expect = 1e-28
Identities = 120/473 (25%), Positives = 201/473 (42%), Gaps = 74/473 (15%)
Query: 38 VFLATFAAVLGN-FSFGYALVYTSPVIPALE------------RSLDPD-LHLTKSQASW 83
+ +A+ A G+ F +GY L + P ++ R +DPD L L S
Sbjct: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV- 85
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFS---AVPSAAGYALMAGAHGLWMLLLGRT 140
S+F +G G L ++ +LGRK +++ + A+ +A A A ML++GR
Sbjct: 86 --SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 143
Query: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----PWR 194
+ G GG+ + +P+Y+SEI+P +RG+LG + G + LGL LL W
Sbjct: 144 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 203
Query: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQI-- 251
+L P ++ +L L F+P+SPR+LL +E A++A G DV E E++
Sbjct: 204 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLG-KADVSQEVEEVLA 262
Query: 252 QDNVRRQSSRVSWAE-ARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
+ V+R VS E RAP+V + ++ QL G+ I Y SIF + P
Sbjct: 263 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P 320
Query: 311 PKDDAAI---VGAVRLLSVLIAALTMDLAGRK---------------------------- 339
P + G + L+ + + L ++ GR+
Sbjct: 321 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAP 380
Query: 340 ---------VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390
+L ++ + G G I ++L E R A + +WL+ F + F
Sbjct: 381 WVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLF 440
Query: 391 LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSF 443
P + F FA IC+ ++ +PETK R+ +I F +++
Sbjct: 441 -PFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY 492
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 124 bits (311), Expect = 2e-28
Identities = 114/405 (28%), Positives = 180/405 (44%), Gaps = 59/405 (14%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLT 142
S+F G G L L + GRK +++F+ + S LM A ++++ R L
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 143 GFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRWL 196
G G+++ +P+Y+ E+AP +RGALG PQL G L GL LL W L
Sbjct: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195
Query: 197 AVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEAL-RALAWLRGTDVDVHWEFEQI--QD 253
P + +LLL F P SPR+LL + +DE A +AL LRG D V E +I +D
Sbjct: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWD-SVDREVAEIRQED 254
Query: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRL-LQQLTGITPILVYLQSIFDSTAVLLPPK 312
+ + +S + R +++++ + QQL+G+ I Y I+ S V P+
Sbjct: 255 EAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV---PE 311
Query: 313 DDAAIV----GAVRLLSVLIAALTMDLAGRKVLL-------------------------- 342
+ V GAV ++ A ++L GR++LL
Sbjct: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSW 371
Query: 343 -----------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFL 391
+V G+A+G PI LL++E+ +R A + WL+ F + F
Sbjct: 372 MPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFP 431
Query: 392 PVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
+ G F FA ICL++ ++ VPETK ++ +I F
Sbjct: 432 FIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 121 bits (303), Expect = 1e-27
Identities = 94/330 (28%), Positives = 157/330 (47%), Gaps = 35/330 (10%)
Query: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAA-GG 96
V++ + LG F FGY S + L+R L D + S T+GAAA
Sbjct: 81 VYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVS-----STVGAAAVSA 135
Query: 97 LSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVY 156
L+ LN + GR+ +I+ ++ AG A++A A+ LL GR + G G+ + +PVY
Sbjct: 136 LAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVY 195
Query: 157 VSEIAPPGVRGALGATPQLMAV----FGSLSLYALGLLLP--WRWLAVAGEAPVLIMILL 210
++E++PP +RG L L F S+ A L WR++ P +I
Sbjct: 196 IAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFG 255
Query: 211 LSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAP 270
F+P SPR+L+ +G+ ++A R L+ +RG + E++ I++N+ + V A P
Sbjct: 256 FLFLPESPRWLIQKGQTQKARRILSQMRGNQT-IDEEYDSIKNNIEEEEKEVGSA---GP 311
Query: 271 HVCR-----PITVALL----MRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD------A 315
+CR P AL+ +++ QQL+GI I+ Y +I + V +DD A
Sbjct: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV----EDDRLAIWLA 367
Query: 316 AIVGAVRLLSVLIAALTMDLAGRKVLLFVS 345
++ + L+ ++ GR+ L F S
Sbjct: 368 SVTAFTNFIFTLVGVWLVEKVGRRKLTFGS 397
Score = 67.4 bits (163), Expect = 2e-11
Identities = 33/97 (34%), Positives = 53/97 (54%)
Query: 340 VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGL 399
++L++ +A G GP+ W + SE+ PL AR + +W+ +++ +FL
Sbjct: 513 LILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTY 572
Query: 400 QVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
FF +A V L+F C+PETKG+ LE+IES F
Sbjct: 573 YGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLF 609
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 117 bits (292), Expect = 3e-26
Identities = 124/465 (26%), Positives = 204/465 (43%), Gaps = 77/465 (16%)
Query: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83
R+ L T A + G F FGY L + +P + E + + PD HL S
Sbjct: 18 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 76
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138
S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG
Sbjct: 77 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 134
Query: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192
R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL
Sbjct: 135 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 194
Query: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251
W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++
Sbjct: 195 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 253
Query: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308
++ + +R W + + R +T +++ +L G + Y S+F V
Sbjct: 254 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 313
Query: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL------------------------- 342
A I G+ LL+ +++ + ++ GR+VLL
Sbjct: 314 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFP 373
Query: 343 ------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390
F+ + +G +T +L +E+ AR A +C W+ ++ F
Sbjct: 374 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 433
Query: 391 ---LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432
+ +S F L VPF +C+ ++TG +PETKG++ ++I
Sbjct: 434 PFIMEALSHF-LYVPFL---GVCVCGAIYTGLFLPETKGKTFQEI 474
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 117 bits (292), Expect = 3e-26
Identities = 124/465 (26%), Positives = 204/465 (43%), Gaps = 77/465 (16%)
Query: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83
R+ L T A + G F FGY L + +P + E + + PD HL S
Sbjct: 11 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 69
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138
S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG
Sbjct: 70 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 127
Query: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192
R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL
Sbjct: 128 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 187
Query: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251
W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++
Sbjct: 188 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 246
Query: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308
++ + +R W + + R +T +++ +L G + Y S+F V
Sbjct: 247 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 306
Query: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL------------------------- 342
A I G+ LL+ +++ + ++ GR+VLL
Sbjct: 307 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFP 366
Query: 343 ------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390
F+ + +G +T +L +E+ AR A +C W+ ++ F
Sbjct: 367 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 426
Query: 391 ---LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432
+ +S F L VPF +C+ ++TG +PETKG++ ++I
Sbjct: 427 PFIMEALSHF-LYVPFL---GVCVCGAIYTGLFLPETKGKTFQEI 467
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 117 bits (292), Expect = 3e-26
Identities = 124/465 (26%), Positives = 204/465 (43%), Gaps = 77/465 (16%)
Query: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83
R+ L T A + G F FGY L + +P + E + + PD HL S
Sbjct: 14 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 72
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138
S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG
Sbjct: 73 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 130
Query: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192
R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL
Sbjct: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 190
Query: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251
W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++
Sbjct: 191 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 249
Query: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308
++ + +R W + + R +T +++ +L G + Y S+F V
Sbjct: 250 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 309
Query: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL------------------------- 342
A I G+ LL+ +++ + ++ GR+VLL
Sbjct: 310 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFP 369
Query: 343 ------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390
F+ + +G +T +L +E+ AR A +C W+ ++ F
Sbjct: 370 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 429
Query: 391 ---LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432
+ +S F L VPF +C+ ++TG +PETKG++ ++I
Sbjct: 430 PFIMEALSHF-LYVPFL---GVCVCGAIYTGLFLPETKGKTFQEI 470
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 90.9 bits (224), Expect = 2e-18
Identities = 82/328 (25%), Positives = 144/328 (43%), Gaps = 19/328 (5%)
Query: 39 FLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLS 98
FL++ A + GY L S + ++ L H + S +GA L+
Sbjct: 41 FLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCH----EQEMVVSSLVIGALLASLT 96
Query: 99 AMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVS 158
+L D GR+ +I+ S+ G ++ + +L++GR G + L++ VY++
Sbjct: 97 GGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIA 156
Query: 159 EIAPPGVRGALGATPQLMAVFGSLSLYA-----LGLLLPWRWLAVAGEAPVLIMILLLSF 213
EIAP RG L + +LM V G LS Y + W+++ ++ + + F
Sbjct: 157 EIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYF 216
Query: 214 MPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVC 273
+P SPRFL+ +G++ A + L LR D E I+ +++ + W R+
Sbjct: 217 LPPSPRFLVMKGQEGAASKVLGRLRALS-DTTEELTVIKSSLKDEYQYSFWDLFRSKDNM 275
Query: 274 RP-ITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI-----VGAVRLLSVL 327
R I + L + Q+TG IL Y ++ S ++AA VG V+++S +
Sbjct: 276 RTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF---QSNEAASLASTGVGVVKVISTI 332
Query: 328 IAALTMDLAGRKVLLFVSGYAVGWGPIT 355
A L +D G K L + + +T
Sbjct: 333 PATLLVDHVGSKTFLCIGSSVMAASLVT 360
Score = 70.1 bits (170), Expect = 4e-12
Identities = 35/93 (37%), Positives = 55/93 (59%)
Query: 340 VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGL 399
+L++V+ +++G GP+ WL++SE+ P RG A L +W +++ +FL V GL
Sbjct: 468 LLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGL 527
Query: 400 QVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432
F + + L SL+F +PETKG SLEQI
Sbjct: 528 PWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 89.7 bits (221), Expect = 5e-18
Identities = 96/325 (29%), Positives = 140/325 (43%), Gaps = 56/325 (17%)
Query: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSA 99
L ++LG +FGY L S + L+ D L+ + + LGA L
Sbjct: 10 LCASVSLLGGLTFGYELAVISGALLPLQL----DFGLSCLEQEFLVGSLLLGALLASLVG 65
Query: 100 MILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSE 159
L D GRK +I+ S + AG + A L L+LGR + GFA L++ +YVSE
Sbjct: 66 GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125
Query: 160 IAPPGVRGALGATPQLMAVFGSLSLYALGLLL---PWRWLAVAG--EAPVLIMILLLSFM 214
+ P RG L + + G L YAL L PW W + G AP ++ L L F+
Sbjct: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185
Query: 215 PNSPRFLLSRGRDEEAL-RALAWLRGTDVD---------VHWEFEQIQDNVRRQSSRVSW 264
P G DE A + L L+G + + + +DN+R ++
Sbjct: 186 P--------AGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT----- 232
Query: 265 AEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFD-------STAVLLPPKDDAAI 317
TV L + L QQLTG +L Y +IF S+AVL +
Sbjct: 233 ------------TVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLA-----SVG 275
Query: 318 VGAVRLLSVLIAALTMDLAGRKVLL 342
+GAV++ + L A +D AGR+ LL
Sbjct: 276 LGAVKVAATLTAMGLVDRAGRRALL 300
Score = 80.5 bits (197), Expect = 3e-15
Identities = 37/101 (36%), Positives = 60/101 (59%)
Query: 340 VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGL 399
+++FVS ++ G+GP+TWL++SE+ P+ RG A C +W ++ SFL ++ T GL
Sbjct: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
Query: 400 QVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGR 440
F + ++ L F VPETKG+SL +I+ F+ R
Sbjct: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRR 516
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 72.4 bits (176), Expect = 8e-13
Identities = 97/393 (24%), Positives = 165/393 (41%), Gaps = 42/393 (10%)
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTG 143
F S G G L D GRKL ++ + + +A LMA + +LL R L G
Sbjct: 151 FQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQG 210
Query: 144 FAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEA 202
++E G R + Q+ G ++L L LP WRWL +A
Sbjct: 211 LVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSL 270
Query: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRA---LAWLRGTDVDVHWEFEQIQDNVRRQS 259
P + +L +P SPR+LLS+ R+ EA++ +A G + ++++V +
Sbjct: 271 PTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKL 330
Query: 260 SRVSWAEARAPHVCRP--------ITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPP 311
S R P + + T ++L + L G T +YL ++ +A++ P
Sbjct: 331 SPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLY--SALVEIP 388
Query: 312 KDDAAIVGAVRLLSVLIAALTMDLAGRK--VLLFVSG---------YAVGWGPIT----- 355
A++ R+ + A++ LAG V++F+S VG IT
Sbjct: 389 GAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQM 448
Query: 356 -WLLMSEVLPLRARG----VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAIC 410
L+ +E+ P R V S LC + +T F++ + + +P FA +
Sbjct: 449 ICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFR-----LREVWQALPLILFAVLG 503
Query: 411 LVSLVFTGCCVPETKGRSL-EQIESFFRTGRRS 442
L++ T +PETKG +L E ++ GR++
Sbjct: 504 LLAAGVT-LLLPETKGVALPETMKDAENLGRKA 535
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 66.6 bits (161), Expect = 4e-11
Identities = 86/385 (22%), Positives = 156/385 (40%), Gaps = 49/385 (12%)
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTG 143
F S +G G +S + D GRKL ++ + + +AA LMA + +L+ R + G
Sbjct: 152 FQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQG 211
Query: 144 FAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEA 202
+ ++E R +G Q+ G L L + LP WRWL
Sbjct: 212 LVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVAL 271
Query: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRA---LAWLRGTDVDVHWEFEQIQDNVRRQS 259
P +L +P SPR+L+S+ ++ EA+R +A G + + ++++ ++
Sbjct: 272 PNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKL 331
Query: 260 SRVSWAEARAPHVCRP--------ITVALLMRLLQQLTGITPILVYLQSIF--------- 302
+ R P + + T ++L + L G+ +YL +
Sbjct: 332 NPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAA 391
Query: 303 -------DSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFV---SGYAVGWG 352
D P + GA L SV I DL K+++ G + +
Sbjct: 392 FMIILTIDRIGRRYPWAASNMVAGAACLASVFIPG---DLQWLKIIISCLGRMGITMAY- 447
Query: 353 PITWLLMSEVLPLRARG----VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAA 408
I L+ +E+ P R + S +C + +T F++ + ++ L++P F
Sbjct: 448 EIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYR-----LTNIWLELPLMVFGV 502
Query: 409 ICLVS--LVFTGCCVPETKGRSLEQ 431
+ LV+ LV +PETKG++L +
Sbjct: 503 LGLVAGGLVL---LLPETKGKALPE 524
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 66.2 bits (160), Expect = 6e-11
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTG 143
F S G G L D GRKL ++ + + +A LMA + +LL R L G
Sbjct: 151 FQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQG 210
Query: 144 FAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEA 202
++E G R + Q+ G ++L L LP WRWL +A
Sbjct: 211 LVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSL 270
Query: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
P + +L +P SPR+LLS+ R+ EA++ +
Sbjct: 271 PTFLFLLYYWCVPESPRWLLSQKRNTEAIKIM 302
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/200 (25%), Positives = 83/200 (41%), Gaps = 17/200 (8%)
Query: 69 SLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG 128
S + DL + S + W GS+ LG G L D +GRK S++ + L +
Sbjct: 178 SAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSF 237
Query: 129 AHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALG 188
G L R L+GF G + Y +E+ RG + + + G + A+
Sbjct: 238 VQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMA 297
Query: 189 -LLLP----------------WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEAL 231
++P WR + P + ++ L+FMP SPRFLL G+ +EA
Sbjct: 298 WAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAW 357
Query: 232 RALAWLRGTDVDVHWEFEQI 251
L + T++ + E++
Sbjct: 358 MILKLIHDTNMRARGQPEKV 377
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 59.7 bits (143), Expect = 5e-09
Identities = 90/389 (23%), Positives = 154/389 (39%), Gaps = 63/389 (16%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
++ LG G + D GR + + S + ++A A + ++ R L G
Sbjct: 159 AILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVF 218
Query: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEAPV 204
G T V V+EI R +G Q+ G + L + +P W+ + +A P
Sbjct: 219 GKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPS 278
Query: 205 LIMILLLSFMPNSPRFLLSRGRDEEA---LRALAWLRGTDVDVHWEFEQIQDNVRRQSSR 261
+ +L +P SPR+L++R + ++A LR +A G + ++ + D + S
Sbjct: 279 FLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTD---EEVSN 335
Query: 262 VSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAV 321
S+ + R T+ L+ +++ L I + + D I G V
Sbjct: 336 PSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYI------DFFISGVV 389
Query: 322 RLLSVLIAALTMDLAGRKVLLFVSGYAVG--------------W---------------- 351
L L+ LT++ GR++ S G W
Sbjct: 390 ELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMA 449
Query: 352 GPITWLLMSEVLP--LRARGVA--SGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFF- 406
I +L+ SE+ P LR GV+ SGLC + F+L + ++ L++P F
Sbjct: 450 FEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFR-----LAAVWLELPLIIFG 504
Query: 407 --AAIC--LVSLVFTGCCVPETKGRSLEQ 431
A+IC LV L +PETKG +L +
Sbjct: 505 ILASICGGLVML------LPETKGIALPE 527
>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
Length = 683
Score = 59.7 bits (143), Expect = 5e-09
Identities = 55/217 (25%), Positives = 87/217 (40%), Gaps = 21/217 (9%)
Query: 43 FAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMIL 102
F L + G + S +P+ E+ D+ L+ S+ G + LG AG L
Sbjct: 113 FVLGLALMADGVEVFVVSFALPSAEK----DMCLSSSKKGMLGMIVYLGMMAGAFILGGL 168
Query: 103 NDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAP 162
D LGRK + S +A+ +L + G L R ++G G + Y SE
Sbjct: 169 ADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLS 228
Query: 163 PGVRGALGATPQLMAVFGSLSLYALGL-LLP----------------WRWLAVAGEAPVL 205
RG + + + G L A+ ++P WR + P
Sbjct: 229 REKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCT 288
Query: 206 IMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDV 242
+ ++ L FMP SPRFLL G+ +EA L + T++
Sbjct: 289 VSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNM 325
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 59.3 bits (142), Expect = 7e-09
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLT 142
S+F G G L L + GRK +++F+ + S LM A ++++ R L
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 143 GFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL 189
G G+++ +P+Y+ E+AP +RGALG PQL G L GL
Sbjct: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGL 182
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 57.8 bits (138), Expect = 2e-08
Identities = 87/330 (26%), Positives = 143/330 (43%), Gaps = 43/330 (13%)
Query: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA-G 146
F G G ++ L+D GR+ ++ + V + A + M + RTLTG A
Sbjct: 151 FFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALA 210
Query: 147 GLTAACIPVYVS--EIAPPGVRGALGATPQLMAVFGSLSLYALGLLL-PWRWLAVAGEAP 203
G T +P+ + ++ V G L +T G + L +G L+ WRWL +A P
Sbjct: 211 GFTIIVMPLELEWLDVEHRTVAGVLSST---FWTGGVMLLALVGYLIRDWRWLLLAVTLP 267
Query: 204 VLIMILLLSFMPNSPRFLLSRGRDEEALRAL---AWLRGTDVDVHWEFEQIQDNVRRQSS 260
IL L ++P S R+LL++G +EA R L A L G V +D+ +++
Sbjct: 268 CAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPV--------CEDSFSQEA- 318
Query: 261 RVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIF-------DSTAVLLPPKD 313
VS A V RP + L + + ++V+ F D + + L
Sbjct: 319 -VSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQ 377
Query: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLL--FVSGYAVGWGPITWLLMSE-------VLP 364
+ GAV L S L+ L++ AGR++ + G A+ +G T LL+S VL
Sbjct: 378 TQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFG--TRLLVSSDMKSWSTVLA 435
Query: 365 LRARGVASGLCVLASWLTAFVLTKSFLPVV 394
+ + + A++ TA++ T P V
Sbjct: 436 VMGKAFSE-----AAFTTAYLFTSELYPTV 460
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 57.8 bits (138), Expect = 2e-08
Identities = 87/330 (26%), Positives = 143/330 (43%), Gaps = 43/330 (13%)
Query: 88 FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA-G 146
F G G ++ L+D GR+ ++ + V + A + M + RTLTG A
Sbjct: 149 FFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALA 208
Query: 147 GLTAACIPVYVS--EIAPPGVRGALGATPQLMAVFGSLSLYALGLLL-PWRWLAVAGEAP 203
G T +P+ + ++ V G L +T G + L +G L+ WRWL +A P
Sbjct: 209 GFTIIVMPLELEWLDVEHRTVAGVLSST---FWTGGVMLLALVGYLIRDWRWLLLAVTLP 265
Query: 204 VLIMILLLSFMPNSPRFLLSRGRDEEALRAL---AWLRGTDVDVHWEFEQIQDNVRRQSS 260
IL L ++P S R+LL++G +EA R L A L G V +D+ +++
Sbjct: 266 CAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPV--------CEDSFSQEA- 316
Query: 261 RVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIF-------DSTAVLLPPKD 313
VS A V RP + L + + ++V+ F D + + L
Sbjct: 317 -VSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQ 375
Query: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLL--FVSGYAVGWGPITWLLMSE-------VLP 364
+ GAV L S L+ L++ AGR++ + G A+ +G T LL+S VL
Sbjct: 376 TQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFG--TRLLVSSDMKSWSTVLA 433
Query: 365 LRARGVASGLCVLASWLTAFVLTKSFLPVV 394
+ + + A++ TA++ T P V
Sbjct: 434 VMGKAFSE-----AAFTTAYLFTSELYPTV 458
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 3/151 (1%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
S+F G GGL L+D GR+ + S + AA + A + + ++ R L GF
Sbjct: 127 SIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFG 186
Query: 146 -GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP-WRWLAVAGEAP 203
G+T + + + V E P +R + FG L L +P WRWL + P
Sbjct: 187 ISGITLSTVILNV-EWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIP 245
Query: 204 VLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
+ L + P S R+L+ G+ +AL+ L
Sbjct: 246 FFVFFLSSWWTPESIRWLVLSGKSSKALKIL 276
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 9/173 (5%)
Query: 70 LDPDLHLTKSQASWFGSVFTLGAAAGGLSAMIL----NDLLGRKLSIMFSAVPSAAGYAL 125
L P LH SW ++ T G +S+ L +D GRK + S + + L
Sbjct: 107 LAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGIL 166
Query: 126 MAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLY 185
A A +L+ R L GF G + +Y +E P R ++ G++
Sbjct: 167 SAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEV 225
Query: 186 ALGLL----LPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
L + L WRWL + P+L+ +L ++P S R+ + G E+A+ L
Sbjct: 226 VLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATL 278
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 49.3 bits (116), Expect = 7e-06
Identities = 74/324 (22%), Positives = 132/324 (40%), Gaps = 29/324 (8%)
Query: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA-----GAHGLWMLLLGRT 140
SV+ G G L D LG K +++S + AA A A A+ ++ L+G T
Sbjct: 141 SVYMAGVLVGAAVFGSLADRLGCKGPLVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMT 200
Query: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLL-PWRWLAVA 199
+G L + + V E P R G G L L + L+ PWR L A
Sbjct: 201 FSGII--LNSVSLVV---EWMPTRGRTVAGILLGYSFTLGQLILAGVAYLIRPWRCLQFA 255
Query: 200 GEAPVLIMILLLSFMPNSPRFLLSRGRDEEA---LRALAWLRGTDVDVHWEFEQIQDN-V 255
AP LI L ++P S R+LL G+ + A L+ +A + G + +++ + +
Sbjct: 256 ISAPFLIFFLYSWWLPESSRWLLLHGKSQLAVQNLQKVAAMNGRKEEGERLTKEVMSSYI 315
Query: 256 RRQSSRVSWAEA-----RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
+ + + V + + R P + R +T L++ + + LQ S ++
Sbjct: 316 QSEFASVCTSNSILDLFRTPAI-RKVTCCLMVIWFSNSVAYYGLAMDLQKFGLSLYLV-- 372
Query: 311 PKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSGYAVGWGPITWLLMSEVLPL--RAR 368
A+ G + ++L+A TM GR+ + G I + + E + A+
Sbjct: 373 ----QALFGIINTPAMLVATATMIYVGRRATVASFLILAGLMVIANMFVPEGTQILCTAQ 428
Query: 369 GVASGLCVLASWLTAFVLTKSFLP 392
C+ +S++ ++ T P
Sbjct: 429 AALGKGCLASSFICVYLFTGELYP 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,433,132
Number of Sequences: 37866
Number of extensions: 683638
Number of successful extensions: 2941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2795
Number of HSP's gapped (non-prelim): 103
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.