Guide to the Human Genome
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Search of human proteins with 223005906

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
         (438 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]        918   0.0  
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]                735   0.0  
gi|41152235 ubiquitin specific protease 51 [Homo sapiens]             648   0.0  
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]                  179   4e-45
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi...   170   3e-42
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]   164   2e-40
gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ...   158   8e-39
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]            157   2e-38
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]            157   2e-38
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]            157   2e-38
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ...   155   7e-38
gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ...   155   7e-38
gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ...   155   7e-38
gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ...   155   7e-38
gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ...   155   9e-38
gi|153792150 deubiquitinating enzyme 3 [Homo sapiens]                 154   1e-37
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ...   154   2e-37
gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo ...   154   2e-37
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...   153   3e-37
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...   153   3e-37
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...   153   3e-37
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...   153   3e-37
gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17...   153   3e-37
gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...   153   3e-37
gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...   153   3e-37
gi|113415476 PREDICTED: similar to deubiquitinating enzyme 3 [Ho...   153   3e-37
gi|239742293 PREDICTED: hypothetical protein XP_002342478 [Homo ...   153   3e-37
gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo ...   152   6e-37
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ...   152   6e-37
gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo ...   152   6e-37

>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
          Length = 438

 Score =  918 bits (2373), Expect = 0.0
 Identities = 438/438 (100%), Positives = 438/438 (100%)

Query: 1   MCKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELL 60
           MCKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELL
Sbjct: 1   MCKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELL 60

Query: 61  GHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL 120
           GHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL
Sbjct: 61  GHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL 120

Query: 121 CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHC 180
           CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHC
Sbjct: 121 CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHC 180

Query: 181 KGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSF 240
           KGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSF
Sbjct: 181 KGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSF 240

Query: 241 WPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMN 300
           WPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMN
Sbjct: 241 WPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMN 300

Query: 301 KLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNN 360
           KLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNN
Sbjct: 301 KLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNN 360

Query: 361 ENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHK 420
           ENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHK
Sbjct: 361 ENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHK 420

Query: 421 QVLEHESEKVKEMNTQAY 438
           QVLEHESEKVKEMNTQAY
Sbjct: 421 QVLEHESEKVKEMNTQAY 438


>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
          Length = 525

 Score =  735 bits (1897), Expect = 0.0
 Identities = 352/427 (82%), Positives = 375/427 (87%), Gaps = 16/427 (3%)

Query: 1   MCKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELL 60
           +C+DY+YDKD+E IAKEEQ +A K+Q               G+GEKF TWE TK ELELL
Sbjct: 114 LCQDYIYDKDMEIIAKEEQRKAWKMQ---------------GVGEKFSTWEPTKRELELL 158

Query: 61  GHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL 120
            HNP+RR+ITS+ TIGLRGLINLGNTCFMNCIVQALTHTP+LRDFFLSDRHRCEM SP  
Sbjct: 159 KHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSS 218

Query: 121 CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHC 180
           CLVCEMSSLF+E YSG+ SPH+PYKLLHLVW HARHLAGY QQDAHEFLIAALDVLHRHC
Sbjct: 219 CLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHC 278

Query: 181 KGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSF 240
           KGDD GK ANNPNHCNCIIDQIFTGGLQSDVTCQ CHGVSTTIDP WDISLDLPGS T F
Sbjct: 279 KGDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPF 338

Query: 241 WPMSPGRESS-VNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTM 299
           WP+SPG E + VNGESH+ G TTLTDCLRRFTRPEHLGSSAKIKC  C SYQESTKQLTM
Sbjct: 339 WPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTM 398

Query: 300 NKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGN 359
            KLP+VACFH KRFEHSAK RRKITTY+SFPLELDMTPFMASSKESRMNGQ Q PT+S N
Sbjct: 399 KKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLN 458

Query: 360 NENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYH 419
           N+NKYSLFAVVNHQGTLESGHYTSFIR HKDQWFKCDDA+ITKASIKDVLDSEGYLLFYH
Sbjct: 459 NDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYH 518

Query: 420 KQVLEHE 426
           KQ LE+E
Sbjct: 519 KQFLEYE 525


>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
          Length = 711

 Score =  648 bits (1672), Expect = 0.0
 Identities = 315/427 (73%), Positives = 357/427 (83%), Gaps = 3/427 (0%)

Query: 1   MCKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELL 60
           MCKDYVYDKDIEQIAKE + + L+L  STST+VSHQQ    G  +K  T ET + E +L+
Sbjct: 287 MCKDYVYDKDIEQIAKETKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETKEQEPKLV 346

Query: 61  GHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL 120
               +RR+  S +T+GLRGLINLGNTCFMNCIVQALTH P+L+DFFLSD+H+C M SP L
Sbjct: 347 KPKKKRRK-KSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSL 405

Query: 121 CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHC 180
           CLVCEMSSLF  +YSG+ +PH+PYKLLHL+WIHA HLAGYRQQDAHEFLIA LDVLHRH 
Sbjct: 406 CLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHS 465

Query: 181 KGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSF 240
           K D  G+ ANNPN CNCIIDQIFTGGLQSDVTCQACH VSTTIDPCWDISLDLPGSC +F
Sbjct: 466 KDDSGGQEANNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATF 525

Query: 241 WPMSPGR-ESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTM 299
              +P R +S+V+ + HIPGI +LTDCL+ FTRPEHLGSSAKIKC SCQSYQESTKQLTM
Sbjct: 526 DSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTM 585

Query: 300 NKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGN 359
            KLP+VACFH KRFEH  KQRRKI T+ISFPLELDMTPF+AS+KESRM  + Q PT+   
Sbjct: 586 KKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLASTKESRMK-EGQPPTDCVP 644

Query: 360 NENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYH 419
           NENKYSLFAV+NH GTLESGHYTSFIR  KDQWF CDDA+ITKA+I+D+L SEGYLLFYH
Sbjct: 645 NENKYSLFAVINHHGTLESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEGYLLFYH 704

Query: 420 KQVLEHE 426
           KQ LE +
Sbjct: 705 KQGLEKD 711


>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
          Length = 520

 Score =  179 bits (454), Expect = 4e-45
 Identities = 131/398 (32%), Positives = 189/398 (47%), Gaps = 67/398 (16%)

Query: 71  SSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL---------- 120
           S+  I   GL NLGNTCFMN I+Q+L++      +F       E+P+ EL          
Sbjct: 152 STTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFK------ELPAVELRNGKTAGRRT 205

Query: 121 -----------CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFL 169
                       LV E       L+ G+ +   P  L ++VW    +  GY+QQDAHEF+
Sbjct: 206 YHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFM 265

Query: 170 IAALDVLHRHCKGDDVGKA------------ANNP---NHCNCIIDQIFTGGLQSDVTCQ 214
              LD LH   +G   G +            A+N    N  + ++  IF G LQ++V C 
Sbjct: 266 RYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCL 325

Query: 215 ACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPE 274
            C   S   DP  D+SLD+P    S        + S N E+    + +L DCLR FT  E
Sbjct: 326 ICGTESRKFDPFLDLSLDIPSQFRS--------KRSKNQENG--PVCSLRDCLRSFTDLE 375

Query: 275 HLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-L 333
            L  +    C  C+  Q+STK+  + KLP V C H KRF  +A  R K+ TY+ FPL  L
Sbjct: 376 ELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGL 435

Query: 334 DMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGT-LESGHYTSFIRHHKDQW 392
           DM  ++              P NSG     Y L AVV H G+ + SGHYT++   H+ +W
Sbjct: 436 DMKCYLLE------------PENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAT-HEGRW 482

Query: 393 FKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHESEKV 430
           F  +D+ +T    + V+ ++ Y+LFY +   +  S+K+
Sbjct: 483 FHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 520


>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
           sapiens]
          Length = 605

 Score =  170 bits (430), Expect = 3e-42
 Identities = 128/445 (28%), Positives = 199/445 (44%), Gaps = 67/445 (15%)

Query: 2   CKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELE--L 59
           C +Y+ D  +E   ++     +  QA  S        +   +G ++  WET K +     
Sbjct: 191 CPEYLVDY-LENYGRKGSASQVPSQAPPSRVPEIISPTYRPIG-RYTLWETGKGQAPGPS 248

Query: 60  LGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEM---P 116
              +P R  + S    GL GL NLGNTCFMN I+Q L++T  LRD+ L   +  ++    
Sbjct: 249 RSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS 308

Query: 117 SPELCLVCEMSSLFRELYSGNPSPHV-PYKLLHLVWIHARHLAGYRQQDAHEFLIAALDV 175
           +    LV E + L + +++ +P+  V P +    +  +A    GY QQDA EFL   LD 
Sbjct: 309 NAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDG 368

Query: 176 LHRHCKGDDVGKAANNPNHCNCIIDQ--------------------IFTGGLQSDVTCQA 215
           LH       + +  +NP + + + D                     +F G L+S +TC  
Sbjct: 369 LHNEVNRVTL-RPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTD 427

Query: 216 CHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEH 275
           C   ST  DP WD+SL +                    +   P +T L DC+R FT+ + 
Sbjct: 428 CGYCSTVFDPFWDLSLPI-------------------AKRGYPEVT-LMDCMRLFTKEDV 467

Query: 276 LGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPL-ELD 334
           L    K  C  C+  +   K+ ++ + P +   H KRF  S  +  K+TT+++FPL +LD
Sbjct: 468 LDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLD 527

Query: 335 MTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWF 393
           +  F                 +   N   Y+L+AV NH GT   GHYT++ R     +W 
Sbjct: 528 LREF----------------ASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWH 571

Query: 394 KCDDAVITKASIKDVLDSEGYLLFY 418
             +D+ +T  S   V  S+ YLLFY
Sbjct: 572 TFNDSSVTPMSSSQVRTSDAYLLFY 596


>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
          Length = 396

 Score =  164 bits (414), Expect = 2e-40
 Identities = 113/369 (30%), Positives = 171/369 (46%), Gaps = 63/369 (17%)

Query: 76  GLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEM---PSPELCLVCEMSSLFRE 132
           GL GL NLGNTCFMN I+Q L++T  LRD+ L   +  ++    +    LV E + L + 
Sbjct: 56  GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQT 115

Query: 133 LYSGNPSPHV-PYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAANN 191
           +++ +P+  V P +    +  +A    GY QQDA EFL   LD LH       + +  +N
Sbjct: 116 IWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL-RPKSN 174

Query: 192 PNHCNCIIDQ--------------------IFTGGLQSDVTCQACHGVSTTIDPCWDISL 231
           P + + + D                     +F G L+S +TC  C   ST  DP WD+SL
Sbjct: 175 PENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSL 234

Query: 232 DLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQ 291
            +                    +   P +T L DC+R FT+ + L    K  C  C+  +
Sbjct: 235 PI-------------------AKRGYPEVT-LMDCMRLFTKEDVLDGDEKPTCCRCRGRK 274

Query: 292 ESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPL-ELDMTPFMASSKESRMNGQ 350
              K+ ++ + P +   H KRF  S  +  K+TT+++FPL +LD+  F            
Sbjct: 275 RCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF------------ 322

Query: 351 LQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWFKCDDAVITKASIKDVL 409
                +   N   Y+L+AV NH GT   GHYT++ R     +W   +D+ +T  S   V 
Sbjct: 323 ----ASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVR 378

Query: 410 DSEGYLLFY 418
            S+ YLLFY
Sbjct: 379 TSDAYLLFY 387


>gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo
           sapiens]
          Length = 530

 Score =  158 bits (400), Expect = 8e-39
 Identities = 110/358 (30%), Positives = 167/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++P+ 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHPSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQQNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T ASI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTAASITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score =  157 bits (396), Expect = 2e-38
 Identities = 111/373 (29%), Positives = 172/373 (46%), Gaps = 73/373 (19%)

Query: 77   LRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELC-----LVCEMSSLFR 131
            L GL NLGNTC+MN I+Q L + P L D+F  + ++ ++    L      +  E   + +
Sbjct: 776  LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835

Query: 132  ELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAAN- 190
             L++G      P      +       AGY QQD+ E L+  +D LH     +D+ KA N 
Sbjct: 836  ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH-----EDLNKADNR 890

Query: 191  ------NPNHCN-----------------CIIDQIFTGGLQSDVTCQACHGVSTTIDPCW 227
                  N +H +                  II  +F G  +S V C  CH  S T +   
Sbjct: 891  KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950

Query: 228  DISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSC 287
             +SL L  +                         TL DCLR F++ E L  + +  C  C
Sbjct: 951  YLSLPLASTSKC----------------------TLQDCLRLFSKEEKLTDNNRFYCSHC 988

Query: 288  QSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-LDMTPFMASSKESR 346
            ++ ++S K++ + KLP V   H KRF +  + ++K+ T + FPLE LD++ ++   K   
Sbjct: 989  RARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--- 1045

Query: 347  MNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWFKCDDAVITKASI 405
                        NN  KY+LF+V NH G L+ GHYT++ ++  + +WFK DD  ++  S+
Sbjct: 1046 ------------NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV 1093

Query: 406  KDVLDSEGYLLFY 418
              V  S  Y+LFY
Sbjct: 1094 SSVKSSAAYILFY 1106


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score =  157 bits (396), Expect = 2e-38
 Identities = 111/373 (29%), Positives = 172/373 (46%), Gaps = 73/373 (19%)

Query: 77   LRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELC-----LVCEMSSLFR 131
            L GL NLGNTC+MN I+Q L + P L D+F  + ++ ++    L      +  E   + +
Sbjct: 776  LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835

Query: 132  ELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAAN- 190
             L++G      P      +       AGY QQD+ E L+  +D LH     +D+ KA N 
Sbjct: 836  ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH-----EDLNKADNR 890

Query: 191  ------NPNHCN-----------------CIIDQIFTGGLQSDVTCQACHGVSTTIDPCW 227
                  N +H +                  II  +F G  +S V C  CH  S T +   
Sbjct: 891  KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950

Query: 228  DISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSC 287
             +SL L  +                         TL DCLR F++ E L  + +  C  C
Sbjct: 951  YLSLPLASTSKC----------------------TLQDCLRLFSKEEKLTDNNRFYCSHC 988

Query: 288  QSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-LDMTPFMASSKESR 346
            ++ ++S K++ + KLP V   H KRF +  + ++K+ T + FPLE LD++ ++   K   
Sbjct: 989  RARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--- 1045

Query: 347  MNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWFKCDDAVITKASI 405
                        NN  KY+LF+V NH G L+ GHYT++ ++  + +WFK DD  ++  S+
Sbjct: 1046 ------------NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV 1093

Query: 406  KDVLDSEGYLLFY 418
              V  S  Y+LFY
Sbjct: 1094 SSVKSSAAYILFY 1106


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score =  157 bits (396), Expect = 2e-38
 Identities = 111/373 (29%), Positives = 172/373 (46%), Gaps = 73/373 (19%)

Query: 77   LRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELC-----LVCEMSSLFR 131
            L GL NLGNTC+MN I+Q L + P L D+F  + ++ ++    L      +  E   + +
Sbjct: 776  LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835

Query: 132  ELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAAN- 190
             L++G      P      +       AGY QQD+ E L+  +D LH     +D+ KA N 
Sbjct: 836  ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH-----EDLNKADNR 890

Query: 191  ------NPNHCN-----------------CIIDQIFTGGLQSDVTCQACHGVSTTIDPCW 227
                  N +H +                  II  +F G  +S V C  CH  S T +   
Sbjct: 891  KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950

Query: 228  DISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSC 287
             +SL L  +                         TL DCLR F++ E L  + +  C  C
Sbjct: 951  YLSLPLASTSKC----------------------TLQDCLRLFSKEEKLTDNNRFYCSHC 988

Query: 288  QSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-LDMTPFMASSKESR 346
            ++ ++S K++ + KLP V   H KRF +  + ++K+ T + FPLE LD++ ++   K   
Sbjct: 989  RARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--- 1045

Query: 347  MNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWFKCDDAVITKASI 405
                        NN  KY+LF+V NH G L+ GHYT++ ++  + +WFK DD  ++  S+
Sbjct: 1046 ------------NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV 1093

Query: 406  KDVLDSEGYLLFY 418
              V  S  Y+LFY
Sbjct: 1094 SSVKSSAAYILFY 1106


>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1
           [Homo sapiens]
          Length = 530

 Score =  155 bits (392), Expect = 7e-38
 Identities = 109/358 (30%), Positives = 167/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K A++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQADHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQQNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo
           sapiens]
          Length = 530

 Score =  155 bits (392), Expect = 7e-38
 Identities = 111/358 (31%), Positives = 169/358 (47%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+              TN+G     Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQ-------------TNTG--PLVYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo
           sapiens]
          Length = 530

 Score =  155 bits (392), Expect = 7e-38
 Identities = 111/358 (31%), Positives = 169/358 (47%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+              TN+G     Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQ-------------TNTG--PLVYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo
           sapiens]
          Length = 530

 Score =  155 bits (392), Expect = 7e-38
 Identities = 111/358 (31%), Positives = 169/358 (47%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+              TN+G     Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQ-------------TNTG--PLVYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo
           sapiens]
          Length = 530

 Score =  155 bits (391), Expect = 9e-38
 Identities = 109/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQQNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T ASI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTAASITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|153792150 deubiquitinating enzyme 3 [Homo sapiens]
          Length = 530

 Score =  154 bits (390), Expect = 1e-37
 Identities = 107/360 (29%), Positives = 161/360 (44%), Gaps = 63/360 (17%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSSLFRELYSGNP 138
           GL N+GNTC+ N  +Q LT+TP L ++ LS  H      P+ C++C M +          
Sbjct: 81  GLQNMGNTCYENASLQCLTYTPPLANYMLSREHSQTCQRPKCCMLCTMQA---------- 130

Query: 139 SPHVPYKLL---HLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNP 192
             H+ + L    H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ 
Sbjct: 131 --HITWALHSPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHH 186

Query: 193 NHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVN 252
           +    +I QIF G  +S + C  CHG+S T DP  DI+LD                    
Sbjct: 187 SKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALD-------------------- 226

Query: 253 GESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKR 312
               I    ++   L +  +PE L       CG C     ++K LT++    V     KR
Sbjct: 227 ----IQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASKTLTLHTSAKVLILVLKR 282

Query: 313 FEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNH 372
           F  S     K+   + +P  LDM P+M+      +                Y L+AV+ H
Sbjct: 283 F--SDVTGNKLAKNVQYPECLDMQPYMSQQNTGPL---------------VYVLYAVLVH 325

Query: 373 QG-TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            G +   GHY S+++  + QW+K DDA +T  SI  VL  + Y+LFY  K   E  SE V
Sbjct: 326 AGWSCHDGHYFSYVKAQEGQWYKMDDAKVTACSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1
           [Homo sapiens]
          Length = 530

 Score =  154 bits (388), Expect = 2e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQQNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo
           sapiens]
          Length = 530

 Score =  154 bits (388), Expect = 2e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQQNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase
           17-like protein 5 [Homo sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLAKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|113415476 PREDICTED: similar to deubiquitinating enzyme 3 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742293 PREDICTED: hypothetical protein XP_002342478 [Homo
           sapiens]
          Length = 530

 Score =  153 bits (387), Expect = 3e-37
 Identities = 108/358 (30%), Positives = 166/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo
           sapiens]
          Length = 530

 Score =  152 bits (384), Expect = 6e-37
 Identities = 108/358 (30%), Positives = 165/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT+     V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
           sapiens]
          Length = 559

 Score =  152 bits (384), Expect = 6e-37
 Identities = 111/358 (31%), Positives = 168/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT++    V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM  +M+              TNSG     Y L+AV+ H G
Sbjct: 284 -SDVTGNKIDKNVQYPECLDMKLYMSQ-------------TNSG--PLVYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


>gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo
           sapiens]
          Length = 530

 Score =  152 bits (384), Expect = 6e-37
 Identities = 108/358 (30%), Positives = 165/358 (46%), Gaps = 59/358 (16%)

Query: 79  GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSS-LFRELYSGN 137
           GL N+GNTC++N  +Q LT+TP L ++ LS  H       + C++C M + + R L+  N
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--N 138

Query: 138 PSPHVPYKLLHLVWIHARHLAGY---RQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNH 194
           P         H++       AG+   +Q+DAHEFL+  +D + + C      K  ++ + 
Sbjct: 139 PG--------HVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH--KQVDHHSK 188

Query: 195 CNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGE 254
              +I QIF G  +S + C  CHG+S T DP  DI+LD+  +                  
Sbjct: 189 DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAA------------------ 230

Query: 255 SHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFE 314
                  ++   L +  +PE L       CG C     ++K LT+     V     KRF 
Sbjct: 231 ------QSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRF- 283

Query: 315 HSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQG 374
            S     KI   + +P  LDM P+M+      +                Y L+AV+ H G
Sbjct: 284 -SDVTGNKIAKNVQYPECLDMQPYMSQPNTGPL---------------VYVLYAVLVHAG 327

Query: 375 -TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFY-HKQVLEHESEKV 430
            +  +GHY S+++  + QW+K DDA +T +SI  VL  + Y+LFY  K   E  SE V
Sbjct: 328 WSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESV 385


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,773,225
Number of Sequences: 37866
Number of extensions: 815426
Number of successful extensions: 2369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1863
Number of HSP's gapped (non-prelim): 204
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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