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Search of human proteins with 222418611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222418611 integrin alpha 7 isoform 2 precursor [Homo
sapiens]
(1137 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 2298 0.0
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 2218 0.0
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 1941 0.0
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 1008 0.0
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 990 0.0
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 637 0.0
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 628 e-179
gi|49170034 integrin, alpha 8 [Homo sapiens] 343 5e-94
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 321 3e-87
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 319 1e-86
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 305 2e-82
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 302 1e-81
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 288 2e-77
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 287 5e-77
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 257 4e-68
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 224 3e-58
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 185 2e-46
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 162 2e-39
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 160 8e-39
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 156 9e-38
gi|34452173 integrin alpha X precursor [Homo sapiens] 151 4e-36
gi|148728188 integrin, alpha E precursor [Homo sapiens] 150 9e-36
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 149 2e-35
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 138 3e-32
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 137 6e-32
gi|62548866 integrin, alpha D precursor [Homo sapiens] 129 2e-29
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 71 5e-12
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 47 1e-04
gi|32967597 pyruvate kinase, liver and RBC isoform 2 [Homo sapiens] 32 3.4
gi|10835121 pyruvate kinase, liver and RBC isoform 1 [Homo sapiens] 32 3.4
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 2298 bits (5956), Expect = 0.0
Identities = 1137/1137 (100%), Positives = 1137/1137 (100%)
Query: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR
Sbjct: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
Query: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE
Sbjct: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
Query: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
Sbjct: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
Query: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV 240
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV
Sbjct: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV 240
Query: 241 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 300
YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD
Sbjct: 241 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 300
Query: 301 SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN 360
SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN
Sbjct: 301 SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN 360
Query: 361 QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG 420
QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG
Sbjct: 361 QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG 420
Query: 421 VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE 480
VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE
Sbjct: 421 VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE 480
Query: 481 VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV 540
VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV
Sbjct: 481 VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV 540
Query: 541 PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP 600
PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP
Sbjct: 541 PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP 600
Query: 601 RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD 660
RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD
Sbjct: 601 RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD 660
Query: 661 TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS 720
TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS
Sbjct: 661 TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS 720
Query: 721 LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 780
LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV
Sbjct: 721 LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 780
Query: 781 ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV 840
ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV
Sbjct: 781 ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV 840
Query: 841 KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN 900
KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN
Sbjct: 841 KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN 900
Query: 901 ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF 960
ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF
Sbjct: 901 ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF 960
Query: 961 SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI 1020
SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI
Sbjct: 961 SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI 1020
Query: 1021 PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA 1080
PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA
Sbjct: 1021 PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA 1080
Query: 1081 VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1137
VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA
Sbjct: 1081 VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1137
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 2218 bits (5748), Expect = 0.0
Identities = 1109/1147 (96%), Positives = 1113/1147 (97%), Gaps = 16/1147 (1%)
Query: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR
Sbjct: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
Query: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE
Sbjct: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
Query: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
Sbjct: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
Query: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFV----------TN 230
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG V +
Sbjct: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH 240
Query: 231 IDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANH 290
+D + K DP +P PA NSY GFSIDSGKGLVRAEELSFVAGAPRANH
Sbjct: 241 LDDGPYEAGGEKEQDPR-LIPVPA-----NSYFGFSIDSGKGLVRAEELSFVAGAPRANH 294
Query: 291 KGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 350
KGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE
Sbjct: 295 KGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 354
Query: 351 LGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK 410
LGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK
Sbjct: 355 LGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK 414
Query: 411 VFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFR 470
VFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFR
Sbjct: 415 VFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFR 474
Query: 471 ARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA 530
ARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA
Sbjct: 475 ARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA 534
Query: 531 DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV 590
DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV
Sbjct: 535 DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV 594
Query: 591 VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLV 650
VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLV
Sbjct: 595 VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLV 654
Query: 651 RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE 710
RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE
Sbjct: 655 RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE 714
Query: 711 AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG 770
AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG
Sbjct: 715 AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG 774
Query: 771 ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAM 830
ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAM
Sbjct: 775 ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAM 834
Query: 831 QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPG 890
QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPG
Sbjct: 835 QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPG 894
Query: 891 QKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 950
QKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDC
Sbjct: 895 QKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 954
Query: 951 ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 1010
ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN
Sbjct: 955 ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 1014
Query: 1011 LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 1070
LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH
Sbjct: 1015 LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 1074
Query: 1071 PEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDG 1130
PEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDG
Sbjct: 1075 PEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDG 1134
Query: 1131 HPGPGTA 1137
HPGPGTA
Sbjct: 1135 HPGPGTA 1141
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 1941 bits (5027), Expect = 0.0
Identities = 971/1009 (96%), Positives = 975/1009 (96%), Gaps = 16/1009 (1%)
Query: 139 TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 198
TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ
Sbjct: 42 TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
Query: 199 QGTAAAFSPDSHYLLFGAPGTYNWKGLLFV----------TNIDSSDPDQLVYKTLDPAD 248
QGTAAAFSPDSHYLLFGAPGTYNWKG V ++D + K DP
Sbjct: 102 QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPR- 160
Query: 249 RLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 308
+P PA NSY GFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE
Sbjct: 161 LIPVPA-----NSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 215
Query: 309 VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 368
VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI
Sbjct: 216 VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 275
Query: 369 SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV 428
SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV
Sbjct: 276 SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV 335
Query: 429 LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 488
LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI
Sbjct: 336 LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 395
Query: 489 DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR 548
DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR
Sbjct: 396 DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR 455
Query: 549 NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG 608
NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG
Sbjct: 456 NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG 515
Query: 609 QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM 668
QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM
Sbjct: 516 QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM 575
Query: 669 DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA 728
DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA
Sbjct: 576 DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA 635
Query: 729 LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 788
LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS
Sbjct: 636 LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 695
Query: 789 EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 848
EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN
Sbjct: 696 EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 755
Query: 849 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 908
QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS
Sbjct: 756 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
Query: 909 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 968
RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD
Sbjct: 816 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
Query: 969 RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 1028
RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP
Sbjct: 876 RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 935
Query: 1029 MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR 1088
MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR
Sbjct: 936 MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR 995
Query: 1089 QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1137
QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA
Sbjct: 996 QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1044
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 1008 bits (2605), Expect = 0.0
Identities = 528/1110 (47%), Positives = 741/1110 (66%), Gaps = 50/1110 (4%)
Query: 12 ASGICYLFGSLLVELLFSRAVAFNLDVM--GALRKEGEPGSLFGFSVALHRQLQPRPQSW 69
A +C L+ L LL AFNLD +RK G+PGSLFGFS+A+H QLQP +
Sbjct: 4 AGQLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
Query: 70 LLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVR 129
LLVGAP+A ALP Q+ANRTGGL++C ++ C R++ D AD ESKE+QW+GV+V+
Sbjct: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDADPTSESKEDQWMGVTVQ 120
Query: 130 SQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQ 189
SQGPGGK+VTCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +
Sbjct: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
Query: 190 GHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLL---------FVTNIDSSDPDQLV 240
GHE+FG CQQG AA F+ D HY++FGAPGTYNWKG++ F NI P ++
Sbjct: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
Query: 241 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 300
+T +P PA NSYLGFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D
Sbjct: 241 GETEHDESLVPVPA-----NSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRD 295
Query: 301 -SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYL 359
++ L+PE + GE L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+
Sbjct: 296 MKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYM 355
Query: 360 NQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSL 419
NQ G W + P+RL G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+
Sbjct: 356 NQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSAN 415
Query: 420 GVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSH 479
G+ KP+QVL+G + FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++
Sbjct: 416 GINTKPTQVLKGIS---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQK 472
Query: 480 EVSIAPRSIDLEQPNCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRG 538
+++ P IDL Q G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G
Sbjct: 473 TITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSG 532
Query: 539 QVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ 598
RV F ++ EPK+ T LK Q +VC + LQ+N++DKLR I +T S +Q
Sbjct: 533 LSSRVQFRNQG-SEPKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQ 589
Query: 599 TPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 658
P RR+ LP V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR
Sbjct: 590 EPSSRRRV--NSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTRE 646
Query: 659 SDTE-FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVML 717
+ + F LP+ G L L Q I LE+ VTN PS+P P DGDDAHEA+L+
Sbjct: 647 GNQDKFSYLPIQ-KGVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATF 704
Query: 718 PDSLHYSGVRALD--PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIET 775
PD+L YS R L P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T
Sbjct: 705 PDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDT 764
Query: 776 TELEVELLLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSER 834
+L++ L L T S Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE
Sbjct: 765 PDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSED 824
Query: 835 DVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGL 894
+VGS ++YE V N G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K
Sbjct: 825 EVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVT 880
Query: 895 CSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGT 954
C P+ I L++ R++ E E+Q R+ S ++K TL+C+
Sbjct: 881 CEPQKEINSLNLTESHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VN 931
Query: 955 ANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLR 1014
NCV CPL D A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L
Sbjct: 932 VNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLP 991
Query: 1015 DASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEAT 1074
+A T + V V+ GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR+++ + +
Sbjct: 992 NAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSRYDD-S 1050
Query: 1075 VPQYHAVKIPREDRQQFKEEKTGTILRNNW 1104
VP+YHAV+I +E+R+ E+ + + W
Sbjct: 1051 VPRYHAVRIRKEEREIKDEKYIDNLEKKQW 1080
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 990 bits (2559), Expect = 0.0
Identities = 524/1091 (48%), Positives = 726/1091 (66%), Gaps = 54/1091 (4%)
Query: 12 ASGICYLFGSLLVELLFSRAVAFNLDVM--GALRKEGEPGSLFGFSVALHRQLQPRPQSW 69
A +C L+ L LL AFNLD +RK G+PGSLFGFS+A+H QLQP +
Sbjct: 4 AGQLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
Query: 70 LLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVR 129
LLVGAP+A ALP Q+ANRTGGL++C ++ C R++ D AD ESKE+QW+GV+V+
Sbjct: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDADPTSESKEDQWMGVTVQ 120
Query: 130 SQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQ 189
SQGPGGK+VTCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +
Sbjct: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
Query: 190 GHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLL---------FVTNIDSSDPDQLV 240
GHE+FG CQQG AA F+ D HY++FGAPGTYNWKG++ F NI P ++
Sbjct: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
Query: 241 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 300
+T +P PA NSYLGFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D
Sbjct: 241 GETEHDESLVPVPA-----NSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRD 295
Query: 301 -SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYL 359
++ L+PE + GE L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+
Sbjct: 296 MKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYM 355
Query: 360 NQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSL 419
NQ G W + P+RL G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+
Sbjct: 356 NQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSAN 415
Query: 420 GVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSH 479
G+ KP+QVL+G + FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++
Sbjct: 416 GINTKPTQVLKGIS---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQK 472
Query: 480 EVSIAPRSIDLEQPNCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRG 538
+++ P IDL Q G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G
Sbjct: 473 TITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSG 532
Query: 539 QVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ 598
RV F ++ EPK+ T LK Q +VC + LQ+N++DKLR I +T S +Q
Sbjct: 533 LSSRVQFRNQG-SEPKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQ 589
Query: 599 TPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 658
P RR+ LP V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR
Sbjct: 590 EPSSRRRV--NSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTRE 646
Query: 659 SDTE-FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVML 717
+ + F LP+ G L L Q I LE+ VTN PS+P P DGDDAHEA+L+
Sbjct: 647 GNQDKFSYLPIQ-KGVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATF 704
Query: 718 PDSLHYSGVRALD--PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIET 775
PD+L YS R L P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T
Sbjct: 705 PDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDT 764
Query: 776 TELEVELLLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSER 834
+L++ L L T S Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE
Sbjct: 765 PDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSED 824
Query: 835 DVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGL 894
+VGS ++YE V N G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K
Sbjct: 825 EVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVT 880
Query: 895 CSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGT 954
C P+ I L++ R++ E E+Q R+ S ++K TL+C+
Sbjct: 881 CEPQKEINSLNLTESHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VN 931
Query: 955 ANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLR 1014
NCV CPL D A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L
Sbjct: 932 VNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLP 991
Query: 1015 DASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK--HPE 1072
+A T + V V+ GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR K H +
Sbjct: 992 NAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYD 1051
Query: 1073 ATVPQYHAVKI 1083
AT YH +I
Sbjct: 1052 AT---YHKAEI 1059
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 637 bits (1644), Expect = 0.0
Identities = 409/1087 (37%), Positives = 607/1087 (55%), Gaps = 108/1087 (9%)
Query: 33 AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91
AFNLD + KE G PGSLFG+SVALHRQ + + + LL GAP+ LA+P NRTG +
Sbjct: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
Query: 92 FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151
+ CPL+ + DC R++I D E+ WLGV+V SQGP G+++ CAHRY
Sbjct: 92 YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145
Query: 152 QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200
Q+L + R M+G+C+V DL ELD +W + C + + G CQ G
Sbjct: 146 QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200
Query: 201 TAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALN 260
T+ F+ ++ Y FGAPG YNWKG ++ D + YK DP D+ N
Sbjct: 201 TSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYK--DPEDQ---------GN 247
Query: 261 SYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGF 320
Y+G+++ G ++ + ++ V GAPR H GAV +L +++ L +L G ++ + F
Sbjct: 248 LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYF 307
Query: 321 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCGSPDS 379
G ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G P L L G S
Sbjct: 308 GSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGS 367
Query: 380 MFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV---GI 436
FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE + G+
Sbjct: 368 AFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427
Query: 437 KSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCA 496
+FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ PR L+ C
Sbjct: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486
Query: 497 GGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 554
+ CV + +CF+Y A +Y + L Y L+AD DRR PR+ F
Sbjct: 487 A--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG------- 533
Query: 555 HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 614
+++ + C L +N++DKLR I+++++YSL R G
Sbjct: 534 SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593
Query: 615 APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 674
PILN Q E+ F K+ CG D C+SNLQ+ RA F + + L D
Sbjct: 594 YPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSRDVRK 650
Query: 675 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 734
L L + VTN + + G+DAHEA L +++P +L S VR
Sbjct: 651 LL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR-----PP 691
Query: 735 PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-LH 793
C +NE + CELGNP KR ++ + G+++ T +L+V+L L+T S Q+ L
Sbjct: 692 GACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLW 748
Query: 794 PVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSL 853
P+ V L S++ + Q FF G V GE M++ DVGS +KYE V G+ L
Sbjct: 749 PMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGL 808
Query: 854 RTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV----- 906
LG+ L + WP+E++NGKWLLYP ++ + G G P C P ++++ L++
Sbjct: 809 VGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLTLSDP 863
Query: 907 ----DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANCVVFS 961
S RRRR+L+P Q P P ++ +++A+K K+ T L CA G A+CV
Sbjct: 864 GDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHCVWLE 915
Query: 962 CPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIP 1021
CP+ + V R+WNSTF+E+Y + V A + +++SI + + + +T
Sbjct: 916 CPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFS 975
Query: 1022 VMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAV 1081
V + + + + + W++L+AV AGLL+L L++LLLWK FFKR ++ + +P+YHAV
Sbjct: 976 VDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTRYYQ-IMPKYHAV 1034
Query: 1082 KIPREDR 1088
+I E+R
Sbjct: 1035 RIREEER 1041
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 628 bits (1619), Expect = e-179
Identities = 403/1068 (37%), Positives = 595/1068 (55%), Gaps = 107/1068 (10%)
Query: 33 AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91
AFNLD + KE G PGSLFG+SVALHRQ + + + LL GAP+ LA+P NRTG +
Sbjct: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
Query: 92 FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151
+ CPL+ + DC R++I D E+ WLGV+V SQGP G+++ CAHRY
Sbjct: 92 YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145
Query: 152 QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200
Q+L + R M+G+C+V DL ELD +W + C + + G CQ G
Sbjct: 146 QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200
Query: 201 TAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALN 260
T+ F+ ++ Y FGAPG YNWKG ++ D + YK DP D+ N
Sbjct: 201 TSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYK--DPEDQ---------GN 247
Query: 261 SYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGF 320
Y+G+++ G ++ + ++ V GAPR H GAV +L +++ L +L G ++ + F
Sbjct: 248 LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYF 307
Query: 321 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCGSPDS 379
G ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G P L L G S
Sbjct: 308 GSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGS 367
Query: 380 MFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV---GI 436
FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE + G+
Sbjct: 368 AFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGL 427
Query: 437 KSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCA 496
+FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ PR L+ C
Sbjct: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDPALCT 486
Query: 497 GGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 554
+ CV + +CF+Y A +Y + L Y L+AD DRR PR+ F
Sbjct: 487 A--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG------- 533
Query: 555 HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 614
+++ + C L +N++DKLR I+++++YSL R G
Sbjct: 534 SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593
Query: 615 APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 674
PILN Q E+ F K+ CG D C+SNLQ+ RA F + + L D
Sbjct: 594 YPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSRDVRK 650
Query: 675 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 734
L L + VTN + + G+DAHEA L +++P +L S VR
Sbjct: 651 LL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR-----PP 691
Query: 735 PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-LH 793
C +NE + CELGNP KR ++ + G+++ T +L+V+L L+T S Q+ L
Sbjct: 692 GACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLW 748
Query: 794 PVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSL 853
P+ V L S++ + Q FF G V GE M++ DVGS +KYE V G+ L
Sbjct: 749 PMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGL 808
Query: 854 RTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV----- 906
LG+ L + WP+E++NGKWLLYP ++ + G G P C P ++++ L++
Sbjct: 809 VGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLTLSDP 863
Query: 907 ----DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANCVVFS 961
S RRRR+L+P Q P P ++ +++A+K K+ T L CA G A+CV
Sbjct: 864 GDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHCVWLE 915
Query: 962 CPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIP 1021
CP+ + V R+WNSTF+E+Y + V A + +++SI + + + +T
Sbjct: 916 CPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFS 975
Query: 1022 VMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1069
V + + + + + W++L+AV AGLL+L L++LLLWK GFFKRA+
Sbjct: 976 VDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 343 bits (880), Expect = 5e-94
Identities = 337/1165 (28%), Positives = 525/1165 (45%), Gaps = 174/1165 (14%)
Query: 1 MAGARSRDPWGASG-----ICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFS 55
M+ SR P G+ +C +L + L AFNLDV G GS FG++
Sbjct: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA 60
Query: 56 VALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDID----- 109
V H + + +LVGAP+A G ++ CP E C ++ D
Sbjct: 61 VDFH--IPDARTASVLVGAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNR 117
Query: 110 ----QGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFV 165
G E K NQW G +V++ GK+V CA Y R + +D +G C+V
Sbjct: 118 KIRVNGTKEPIEFKSNQWFGATVKAHK--GKVVACAPLYHWRTL--KPTPEKDPVGTCYV 173
Query: 166 LSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGL 225
Q+ + E+ C E G+CQ G + F + L+ G PG++ W+G
Sbjct: 174 AIQNFSAY-----AEFSPCRNSNADPEGQGYCQAGFSLDFYKNGD-LIVGGPGSFYWQGQ 227
Query: 226 LFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLAL-----NSYLGFSIDSGKGLVRAEELS 280
+ ++ + Y D +L G +SYLG+S+ +G+ +++
Sbjct: 228 VITASVADIIAN---YSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQ-E 283
Query: 281 FVAGAPR-ANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIV 339
VAG PR A + G V I+ + + +GE++ S FGY++ V+D+NSDG D++V
Sbjct: 284 LVAGIPRGAQNFGYVSIINSTDMTFIQN---FTGEQMASYFGYTVVVSDVNSDGLDDVLV 340
Query: 340 GAPYFFERQEELG----GAVYVYLNQGGHWAGISPLRLCGSPD-SMFGISLAVLGDLNQD 394
GAP F ER+ E G +Y+YL Q P L G+ FG ++A LGDLNQD
Sbjct: 341 GAPLFMEREFESNPREVGQIYLYL-QVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQD 399
Query: 395 GFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEG----EAVGIKSFGYSLSGSL 447
G+ DIA+G PF G GKV IY+G+ G+ KPSQVL+G AV FG++L G
Sbjct: 400 GYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVP-SGFGFTLRGDS 458
Query: 448 DMDGNQYPDLLVGSLADTAV-LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----C 502
D+D N YPDL+VG+ V ++RARP++ V ++ + P I+LE C S+ C
Sbjct: 459 DIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAAC 518
Query: 503 VDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGT-- 560
LRVC S S + T+ L + D+ ++ +G + R FL HQA
Sbjct: 519 FSLRVCAS--VTGQSIANTIVLMAEVQLDSLKQ-KGAIKRTLFLD------NHQAHRVFP 569
Query: 561 VWLKHQHDRVCGDAMFQLQENV--KDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL 618
+ +K Q C D + L++ +DKL I ++L+YSL + +GL V PIL
Sbjct: 570 LVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFK-----EGL-EVKPIL 623
Query: 619 NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFA 678
N ++ + + H L CGED +C +L+L +
Sbjct: 624 NYYRENIVSEQAHILVD-CGEDNLCVPDLKL-------------------------SARP 657
Query: 679 LSGQPVIGLE---LMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKP 735
Q +IG E +++ N + +G+ A+EA+L VM+P+ Y G+ + +P
Sbjct: 658 DKHQVIIGDENHLMLIIN-------ARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRP 710
Query: 736 LC--LSNENASH-VECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQEL 792
L EN + V C+LGNPM G + L + +E T + + L S +
Sbjct: 711 LSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVP--RLEKTNMSINFDLQIRSSNKD 768
Query: 793 HP----VSARARVFIELPLSIAGMAIPQQLFFS-GVVRGERAMQSERDVGSKVKYEVTVS 847
+P VS + + + I G++ P Q+ E E +VG V++ +
Sbjct: 769 NPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELH 828
Query: 848 NQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVD 907
N G S T+ L + WP A ++LLY ++ GP Q C P PNI
Sbjct: 829 NIGPS--TISDTILEVGWPFS-ARDEFLLYIFHIQT---LGPLQ---CQPNPNI------ 873
Query: 908 SRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI------------TLDCARGTA 955
++++P E + + +K+++ L+C
Sbjct: 874 ----NPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCT--NI 927
Query: 956 NCVVFSCPLYSFD--RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLM 1012
C+ SC + + +AVL V RLW TFL+ + +L +V + + + +
Sbjct: 928 ECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAK 987
Query: 1013 LRDASTVIPV-MVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1071
L + S I +++ P V+ +P WVI+LA+L GLLVLA+L L LWK GFF RA+ P
Sbjct: 988 LPEGSIAIKTSVIWATPN--VSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPP 1045
Query: 1072 EATVPQYHAVKIPREDRQQFKEEKT 1096
+ + DR+Q +KT
Sbjct: 1046 QEDM----------TDREQLTNDKT 1060
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 321 bits (822), Expect = 3e-87
Identities = 311/1108 (28%), Positives = 524/1108 (47%), Gaps = 154/1108 (13%)
Query: 9 PWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQS 68
P GA + L +L+V + A A+NLD + +G S FG++V H R
Sbjct: 7 PRGAGRLRALLLALVVAGI--PAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTR--- 61
Query: 69 WLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDIDQGADMQ-------KESKE 120
W+LVGAP+A + G +F C + + C +D+ +G + +E ++
Sbjct: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121
Query: 121 NQWLGVSVRSQGPG-GKIVTCAHRYE-ARQRVDQILETRDMIGRCFVLSQDLAIRDELDG 178
++W+GVS+ Q G+++ CAHR++ D IL G C+++ +L + G
Sbjct: 122 DEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPH----GFCYIIPSNLQAK----G 173
Query: 179 GEWKFC--EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDP 236
C E + + E+ G CQ G A F+ + ++ GAPG++ W G + V N+
Sbjct: 174 RTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEE--LVVMGAPGSFYWAGTIKVLNLT---- 227
Query: 237 DQLVYKTLDPADRLPGPAGDLALN---SYLGFSIDSGKGLVRAEELSFVAGAPRANHKGA 293
D K D ++ +N +YLG+++ +G + V GAP+ G
Sbjct: 228 DNTYLKLND----------EVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGK 276
Query: 294 VVILRKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG 352
V I R D S L+ SG+++ S FG SL DLN DG DL+VGAP F E ++E
Sbjct: 277 VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE-- 334
Query: 353 GAVYVYLNQG-GHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--G 409
G V VY+N+G G L G+ ++ FG S+A L DL+ DGFPD+A+GAP + D G
Sbjct: 335 GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAG 394
Query: 410 KVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGS-LADTA 466
V+IYHG + G+V + S L G+ + ++ FG S+SG +DMDGN YPD+ VG+ ++D+
Sbjct: 395 AVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
Query: 467 VLFRARPILHVSHEVSI-APRSIDLEQPNCAGGHSV--CVDLRVCFSYIA--VPSSYSPT 521
VL RARP++ V +VSI P SI++ P C G C+++ CFS+ VP
Sbjct: 455 VLLRARPVITV--DVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGE---- 508
Query: 522 VALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN 581
+ L+YVL AD ++ +GQ+PRV F+ L E Q + + L + + C + ++
Sbjct: 509 IGLNYVLMADVAKKEKGQMPRVYFVL--LGETMGQVTEKLQLTYM-EETCRHYVAHVKRR 565
Query: 582 VKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL--NAHQPSTQRAEIHFLKQGCGE 639
V+D + IV +YSL + + LPP+ P+L Q Q+ + F + E
Sbjct: 566 VQDVISPIVFEAAYSLSEHVTGEEE--RELPPLTPVLRWKKGQKIAQKNQTVFERNCRSE 623
Query: 640 DKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPA 699
D C ++LQL + + L +D T AL I L + ++NL
Sbjct: 624 D--CAADLQL------------QGKLLLSSMDEKTLYLALGAVKNISLNISISNL----- 664
Query: 700 QPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGA 758
GDDA++A + + L + + E + + ++C +G P M+ +
Sbjct: 665 -----GDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLESDFLKCSVGFPFMRSKS 717
Query: 759 QVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI-----ELPLSIAGMA 813
+ F +I TS +S E L + + + + + V + E+ SI G+
Sbjct: 718 KYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIM 777
Query: 814 IPQQLFFSGVVRGERAMQSERDVG---SKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIA 870
P + V +Q + D+ + + V N G S TL + ++I +P+ ++
Sbjct: 778 SPTSFVYGESVDAANFIQLD-DLECHFQPINITLQVYNTGPS--TLPGSSVSISFPNRLS 834
Query: 871 NGKWLLYPMQVELEGGQGPGQKGLCS----PRPNILHLDVDSRDRRRRELEPPEQQEPGE 926
+G ++ +Q E+ GQ +KG CS P P I+ P++QE
Sbjct: 835 SGGAEMFHVQ-EMVVGQ---EKGNCSFQKNPTPCII----------------PQEQE--- 871
Query: 927 RQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSF--DRAAVLHVWGRLWNSTF 984
++ + K LDC + +C+ C + + + + ++ L N+
Sbjct: 872 ----NIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIY-MLLNTEI 926
Query: 985 LEEYSAVKSLEVIVRANITVKSSIKNLML-----RDASTVIPVMVYLDPMAVVAEGVPWW 1039
L++ S+ ++ + RA + V +++ + + + + V + L+P V W
Sbjct: 927 LKKDSS-SVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVV----GW 981
Query: 1040 VILLAVLAGLLVLALLVLLLWKMGFFKR 1067
+I +++L G+L+ LL +LLWKMGFF+R
Sbjct: 982 IIAISLLVGILIFLLLAVLLWKMGFFRR 1009
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 319 bits (817), Expect = 1e-86
Identities = 322/1116 (28%), Positives = 509/1116 (45%), Gaps = 141/1116 (12%)
Query: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64
R R G G+ L LL+ L AFNLDV G GS FGF+V
Sbjct: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
Query: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117
+ +LLVGAP+A PG G + C S C ++ D D E
Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
Query: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177
K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D
Sbjct: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
Query: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDS--SD 235
E+ C + + GFCQ G + F+ LL G PG++ W+G L + S
Sbjct: 166 TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQLISDQVAEIVSK 224
Query: 236 PDQLVYKTLDPADRLPGPAGDLALNSYLGFSID----SGKGLVRAEELSFVAGAPRANHK 291
D VY A + +SYLG+S+ +G G+ FV+G PRA
Sbjct: 225 YDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAART 279
Query: 292 -GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 350
G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R +
Sbjct: 280 LGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSD 336
Query: 351 LG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPF 405
G V V L + +L G + FG ++A LGDL+QDGF DIA+ AP+
Sbjct: 337 GKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPY 394
Query: 406 DGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLV 459
G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+V
Sbjct: 395 GGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIV 454
Query: 460 GSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAV 514
G+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C A
Sbjct: 455 GAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--AD 512
Query: 515 PSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCG 572
P L++ ++ D+ + +G + R FL SR+ K+ L + +
Sbjct: 513 GKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI-- 569
Query: 573 DAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHF 632
A + + +DKL I + + Y L R A GL PILN P+ + H
Sbjct: 570 -AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHI 622
Query: 633 LKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVT 692
L CGED +C+ L++ D++ + + + D L
Sbjct: 623 LLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI--------------- 658
Query: 693 NLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECE 749
+ Q G+ A+EA+L+V +P + GV + A L EN + V C+
Sbjct: 659 ------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCD 712
Query: 750 LGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPL 807
LGNPMK G Q+ L S S T ++ +L + + + ++ VS + + + +
Sbjct: 713 LGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAV 772
Query: 808 SIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMW 865
I G++ P +F + E ++E DVG V++ + N G S + A L++ W
Sbjct: 773 EIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQW 829
Query: 866 PHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE-- 923
P++ N LLY + +++G P ++++ + L+ E+ +
Sbjct: 830 PYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTV 877
Query: 924 PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWN 981
G+ + + + + TL C G A C+ C + DR +A+L+V LW
Sbjct: 878 AGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWT 935
Query: 982 STFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGV 1036
TF+ + + S + A+ V + KNL + D ST++ V + P + V
Sbjct: 936 ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PV 992
Query: 1037 PWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072
P WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 993 PVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 1028
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 305 bits (781), Expect = 2e-82
Identities = 328/1115 (29%), Positives = 491/1115 (44%), Gaps = 168/1115 (15%)
Query: 30 RAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQA-LALPGQQANRT 88
R FNLD G PGS FGFSV +R +LVGAP+A + PG +
Sbjct: 38 RVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVS--VLVGAPKANTSQPG--VLQG 93
Query: 89 GGLFACPLSLEETDCYRVDIDQGADMQKES-------------KENQWLGVSVRSQGPGG 135
G ++ CP T C ++ D ES K QW G +VR+ G
Sbjct: 94 GAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRAHG--S 151
Query: 136 KIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFG 195
I+ CA Y R + + D +G C+ LS D R E+ C G
Sbjct: 152 SILACAPLYSWRTEKEPL---SDPVGTCY-LSTDNFTRIL----EYAPCRSDFSWAAGQG 203
Query: 196 FCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTN----IDSSDPDQLVYKTLDPADRLP 251
+CQ G +A F+ +L G PG+Y W+G + +S P+ L+ L
Sbjct: 204 YCQGGFSAEFTKTGRVVL-GGPGSYFWQGQILSATQEQIAESYYPEYLI--NLVQGQLQT 260
Query: 252 GPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 311
A + +SYLG+S+ G+ E FVAG P+ N V + S R +
Sbjct: 261 RQASSIYDDSYLGYSVAVGEFSGDDTE-DFVAGVPKGNLTYGYVTILNGSDIRSLYN--F 317
Query: 312 SGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFER----QEELGGAVYVYLNQGGHWAG 367
SGE++ S FGY++A D+N DG DL+VGAP +R + + G VYVYL H AG
Sbjct: 318 SGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQ---HPAG 374
Query: 368 ISP---LRLCGSPD-SMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLG 420
I P L L G + FG SL LGDL+QDG+ D+A+GAPF G+ G VF++ G G
Sbjct: 375 IEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGG 434
Query: 421 VVAKPSQVLEGEAVGIKS---FGYSLSGSLDMDGNQYPDLLVGSLA-DTAVLFRARPILH 476
+ +KPSQVL+ + FG +L G D+DGN YPDL+VGS D AV++R RPI+
Sbjct: 435 LGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVS 494
Query: 477 VSHEVSIAPRSIDLEQPNCA--GGHSVCVDLRVCFS----YIAVPSSYSPTVALDYVLDA 530
S ++I P + E+ +C+ G C++L C + ++A ++ + LD+
Sbjct: 495 ASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGFTVELQLDW---- 550
Query: 531 DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQL--QENVKDKLRA 588
++ +G V R FL+ + + T+ +++ C + L + +DKL
Sbjct: 551 ---QKQKGGVRRALFLASR----QATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSP 603
Query: 589 IVVTLSYSLQTPRLRRQAP--GQGLPPVAPILNAHQPSTQRAEIHF-LKQGCGEDKICQS 645
I + L++SL QAP GL P H S R E + CGED IC
Sbjct: 604 IHIALNFSLDP-----QAPVDSHGLRPAL-----HYQSKSRIEDKAQILLDCGEDNICVP 653
Query: 646 NLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADG 705
+LQL +V G L + + L N+
Sbjct: 654 DLQL-------------------EVFGEQNHVYLGDKNALNLTFHAQNVGEG-------- 686
Query: 706 DDAHEAQLLVMLPDSLHYSG-VRALDPAEKPLC--LSNENASHVECELGNPMKRGAQVTF 762
A+EA+L V P YSG VR C + + + C+LGNPMK GA +
Sbjct: 687 -GAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWG 745
Query: 763 YLILSTSGI--SIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFF 820
L + + + +T + + ++L ++ + VS R V + +++ G++ P+ + F
Sbjct: 746 GLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAVLF 805
Query: 821 SGVVRGERAM-QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPM 879
R Q E D+G V + + NQG S ++ L + P + G+ LLY
Sbjct: 806 PVSDWHPRDQPQKEEDLGPAVHHVYELINQGPS--SISQGVLELSCPQAL-EGQQLLYVT 862
Query: 880 QVELEGGQGPGQKGL-CSPR----PNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSW 934
+V GL C+ P L LD + +++ E P +
Sbjct: 863 RVT----------GLNCTTNHPINPKGLELDPEGSLHHQQKREAPSR------------- 899
Query: 935 WPVSSAEKKKNITLDCARGTANCVVFSC---PLYSFDRAAVLHVWGRLWNSTFLEEYSAV 991
SSA I L C A C C PL+ + + L + R+W TFL+
Sbjct: 900 ---SSASSGPQI-LKCPE--AECFRLRCELGPLHQQESQS-LQLHFRVWAKTFLQREHQP 952
Query: 992 KSL--EVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGL 1049
SL E + +A + + I L + V A + GVP W+I+LA+L GL
Sbjct: 953 FSLQCEAVYKA-LKMPYRILPRQLPQKERQVATAVQWTK-AEGSYGVPLWIIILAILFGL 1010
Query: 1050 LVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIP 1084
L+L LL+ +L+K+GFFKR+ P T + +K P
Sbjct: 1011 LLLGLLIYILYKLGFFKRSL-PYGTAMEKAQLKPP 1044
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 302 bits (773), Expect = 1e-81
Identities = 301/1052 (28%), Positives = 484/1052 (46%), Gaps = 136/1052 (12%)
Query: 69 WLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKESKEN 121
+LLVGAP+A PG G + C S C ++ D D E K +
Sbjct: 19 FLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLEFKSH 75
Query: 122 QWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEW 181
QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D E+
Sbjct: 76 QWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTKTVEY 123
Query: 182 KFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDS--SDPDQL 239
C + + GFCQ G + F+ LL G PG++ W+G L + S D
Sbjct: 124 APCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQLISDQVAEIVSKYDPN 182
Query: 240 VYKTLDPADRLPGPAGDLALNSYLGFSID----SGKGLVRAEELSFVAGAPRANHK-GAV 294
VY A + +SYLG+S+ +G G+ FV+G PRA G V
Sbjct: 183 VYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMV 237
Query: 295 VILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG-- 352
I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R +
Sbjct: 238 YIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQ 294
Query: 353 --GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDG 409
G V V L + +L G + FG ++A LGDL+QDGF DIA+ AP+ G+
Sbjct: 295 EVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGED 352
Query: 410 K---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL- 462
K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+VG+
Sbjct: 353 KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFG 412
Query: 463 ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSY 518
D A+L+RARP++ V+ + + P ++ + C+ + C ++R C A
Sbjct: 413 VDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGV 470
Query: 519 SPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMF 576
P L++ ++ D+ + +G + R FL SR+ K+ L + + A
Sbjct: 471 LPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYL 526
Query: 577 QLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQG 636
+ + +DKL I + + Y L R A GL PILN P+ + H L
Sbjct: 527 RDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILLD- 579
Query: 637 CGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPS 696
CGED +C+ L++ D++ + + + D L
Sbjct: 580 CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI------------------- 612
Query: 697 DPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNP 753
+ Q G+ A+EA+L+V +P + GV + A L EN + V C+LGNP
Sbjct: 613 --VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 670
Query: 754 MKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAG 811
MK G Q+ L S S T ++ +L + + + ++ VS + + + + I G
Sbjct: 671 MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 730
Query: 812 MAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEI 869
++ P +F + E ++E DVG V++ + N G S + A L++ WP++
Sbjct: 731 VSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY 787
Query: 870 ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGER 927
N LLY + +++G P ++++ + L+ E+ + G+
Sbjct: 788 -NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQG 835
Query: 928 QEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFL 985
+ + + + TL C G A C+ C + DR +A+L+V LW TF+
Sbjct: 836 ERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFM 893
Query: 986 EEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWV 1040
+ + S + A+ V + KNL + D ST++ V + P + VP WV
Sbjct: 894 NKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWV 950
Query: 1041 ILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072
I+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 951 IILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 982
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 288 bits (738), Expect = 2e-77
Identities = 310/1114 (27%), Positives = 498/1114 (44%), Gaps = 173/1114 (15%)
Query: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64
R R G G+ L LL+ L AFNLDV G GS FGF+V
Sbjct: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
Query: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117
+ +LLVGAP+A PG G + C S C ++ D D E
Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
Query: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177
K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D
Sbjct: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
Query: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPD 237
E+ C R +Q + + P+ + + + +
Sbjct: 166 TVEYAPCRSRQLISDQVA----EIVSKYDPNVYSIKYN---------------------N 200
Query: 238 QLVYKTLDPADRLPGPAGDLALNSYLGFSID----SGKGLVRAEELSFVAGAPRANHK-G 292
QL +T A + +SYLG+S+ +G G+ FV+G PRA G
Sbjct: 201 QLATRT----------AQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLG 245
Query: 293 AVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG 352
V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R +
Sbjct: 246 MVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGK 302
Query: 353 ----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDG 407
G V V L + +L G + FG ++A LGDL+QDGF DIA+ AP+ G
Sbjct: 303 LQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGG 360
Query: 408 DGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGS 461
+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+VG+
Sbjct: 361 EDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 420
Query: 462 L-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPS 516
D A+L+RARP++ V+ + + P ++ + C+ + C ++R C A
Sbjct: 421 FGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGK 478
Query: 517 SYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDA 574
P L++ ++ D+ + +G + R FL SR+ K+ L + + A
Sbjct: 479 GVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---A 534
Query: 575 MFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLK 634
+ + +DKL I + + Y L R A GL PILN P+ + H L
Sbjct: 535 YLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILL 588
Query: 635 QGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNL 694
CGED +C+ L++ D++ + + + D L
Sbjct: 589 D-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI----------------- 622
Query: 695 PSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELG 751
+ Q G+ A+EA+L+V +P + GV + A L EN + V C+LG
Sbjct: 623 ----VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLG 678
Query: 752 NPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSI 809
NPMK G Q+ L S S T ++ +L + + + ++ VS + + + + I
Sbjct: 679 NPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEI 738
Query: 810 AGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPH 867
G++ P +F + E ++E DVG V++ + N G S + A L++ WP+
Sbjct: 739 RGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPY 795
Query: 868 EIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PG 925
+ N LLY + +++G P ++++ + L+ E+ + G
Sbjct: 796 KY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAG 843
Query: 926 ERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNST 983
+ + + + + TL C G A C+ C + DR +A+L+V LW T
Sbjct: 844 QGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTET 901
Query: 984 FLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPW 1038
F+ + + S + A+ V + KNL + D ST++ V + P + VP
Sbjct: 902 FMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPV 958
Query: 1039 WVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072
WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 959 WVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 992
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 287 bits (734), Expect = 5e-77
Identities = 318/1106 (28%), Positives = 495/1106 (44%), Gaps = 169/1106 (15%)
Query: 31 AVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG 90
A A NLD + G GS FGFS+ H+ R ++VGAP+ L G TGG
Sbjct: 29 AWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA--IVVGAPRTL---GPSQEETGG 83
Query: 91 LFACPLSLEETDCYRVDIDQ-------GADMQKESKENQWLGVSVRSQGPGGKIVTCA-- 141
+F CP E C + D G+ + K Q LG SV S IV CA
Sbjct: 84 VFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPW 141
Query: 142 HRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFC 197
+ ++ ++ +T +G CF+ + R E+ C G R F +
Sbjct: 142 QHWNVLEKTEEAEKTP--VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWD 194
Query: 198 QQGTAAAFSP---DSHYLLFGAPGTYNWKGLLF---VTNIDSSDPDQLVYKTLDPADRLP 251
++ A FS + L+ GAPG Y + GLL V +I SS ++ +
Sbjct: 195 KRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSF 254
Query: 252 GPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVM 310
+ + Y G+S+ G+ +V GAP + GAV IL DS + +
Sbjct: 255 DSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQRLHR-- 310
Query: 311 LSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN-QGGHW 365
L GE++ S FG+S+AV D+N DG DL+VGAP + E + + G VY++L +G H
Sbjct: 311 LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHA 370
Query: 366 AGISPLRLCGSP-DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGV 421
G L L G+ FG ++A LGDL++DG+ DIAV AP+ G G+V ++ G S G+
Sbjct: 371 LGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGL 430
Query: 422 VAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHE 480
++PSQVL+ +FG+SL G++D+D N YPDL+VG+ A+ ++RA+P++ S +
Sbjct: 431 RSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490
Query: 481 VSI------APRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDR 534
+ + A +S L Q C ++++C A + ++L+ L D +
Sbjct: 491 LLVQDSLNPAVKSCVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQLDRQK 545
Query: 535 RLRGQVPRVTFLSRNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKDKLRAI 589
+G+ RV L Q +GT L +H +C M L++ + +DKL I
Sbjct: 546 PRQGR--RVLLLG-------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPI 596
Query: 590 VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 649
V++L+ SL P AP A +L+ ++ I CGED +C LQL
Sbjct: 597 VLSLNVSL-PPTEAGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCVPQLQL 645
Query: 650 VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 709
+++G P++ V L D A +G+ A+
Sbjct: 646 TA--------------------------SVTGSPLLVGADNVLELQMDAAN---EGEGAY 676
Query: 710 EAQLLVMLPDSLHYSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQVTFYL 764
EA+L V LP HY +RAL + E+ +C EN + V CELGNPMK+ AQ+ +
Sbjct: 677 EAELAVHLPQGAHY--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAM 734
Query: 765 ILSTSGISIETTELEVELLLATISEQE------LHPVSARARVFIELPLSIAGMAIPQQL 818
++S + + +L + + + Q L V RA +EL G + P L
Sbjct: 735 LVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNSFPASL 790
Query: 819 FFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYP 878
+ GER S G KV++ + N G T+ L+I P + + LLY
Sbjct: 791 VVA-AEEGEREQNSLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPSDLLYI 846
Query: 879 MQVELEGG-----QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQ 928
+ ++ +GG Q P GL P P+ +H RDRR+ L PE ++P Q
Sbjct: 847 LDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQPSRLQ 904
Query: 929 EPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWNSTFLE 986
+P + + C +A C V C L R A++ V LW + +
Sbjct: 905 DP---------------VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQ 947
Query: 987 EYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAV 1045
L+ N+ ++ ++ L L + + A+ +P W +L+ V
Sbjct: 948 RPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWWVLVGV 1004
Query: 1046 LAGLLVLALLVLLLWKMGFFKRAKHP 1071
L GLL+L +LVL +WK+GFFKR + P
Sbjct: 1005 LGGLLLLTILVLAMWKVGFFKRNRPP 1030
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 257 bits (657), Expect = 4e-68
Identities = 282/1067 (26%), Positives = 467/1067 (43%), Gaps = 126/1067 (11%)
Query: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
+N+D AL +G +LFG+SV LH R WLLVGAP A L G ++
Sbjct: 34 YNVDTESALLYQGPHNTLFGYSVVLHSHGANR---WLLVGAPTANWLANASVINPGAIYR 90
Query: 94 CPLSLEETD-CYRVDIDQ--GADMQK---ESKENQWLGVSV-RSQGPGGKIVTCAHRYEA 146
C + C ++ + G K E ++NQWLGV++ R G G IVTC HR++
Sbjct: 91 CRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKN 150
Query: 147 RQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGH-EQFGFCQQGTAAAF 205
+ E + G C+ + DL R EL + + E F CQ G ++ +
Sbjct: 151 IFYIKN--ENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYVKKFGENFASCQAGISSFY 206
Query: 206 SPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKT-LDPADRLPGPAGDLALNSYLG 264
+ D ++ GAPG+ W G LFV NI ++ YK LD +++ SYLG
Sbjct: 207 TKD--LIVMGAPGSSYWTGSLFVYNITTNK-----YKAFLDKQNQVK-------FGSYLG 252
Query: 265 FSIDSGKGLVRAEELS-FVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYS 323
+S+ G G R++ + V GAP+ G I D + M G++L S FG S
Sbjct: 253 YSV--GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEM-KGKKLGSYFGAS 309
Query: 324 LAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHWAGISPLRLCGSPD--SM 380
+ DLN+DG+ DL+VGAP +EE G V+VY+N G G L GS +
Sbjct: 310 VCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMNAMETNLVGSDKYAAR 367
Query: 381 FGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGEAV--GI 436
FG S+ LGD++ DGF D+A+GAP + D G ++IY+G + G+ + SQ +EG + +
Sbjct: 368 FGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSL 427
Query: 437 KSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC 495
FG S+SG +D D N Y D+ VG+ +D+AVL R RP++ V +S P S++ + +C
Sbjct: 428 SMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC 486
Query: 496 A--GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEP 553
G SVC+DL +CFSY + L Y + D +R+ PR F S +
Sbjct: 487 VENGWPSVCIDLTLCFSYKG--KEVPGYIVLFYNMSLDVNRKAESP-PRFYFSSNGTSD- 542
Query: 554 KHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPP 613
+G++ + + C ++++V+D L I + +Y L P + + + PP
Sbjct: 543 --VITGSIQVS-SREANCRTHQAFMRKDVRDILTPIQIEAAYHL-GPHVISKRSTEEFPP 598
Query: 614 VAPIL-NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDG 672
+ PIL + + I+F + E+ C ++LQ+ + + +
Sbjct: 599 LQPILQQKKEKDIMKKTINFARFCAHEN--CSADLQVSAKIGFLKPHENK---------- 646
Query: 673 TTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPA 732
A+ + L + + N GDDA+E L V LP L++ ++ L+
Sbjct: 647 --TYLAVGSMKTLMLNVSLFNA----------GDDAYETTLHVKLPVGLYF--IKILELE 692
Query: 733 EKPL---CLSNENASHVECELGN-PMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 788
EK + N ++C +G + +++ +L S +S +L + + +
Sbjct: 693 EKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCEN 752
Query: 789 EQELHPVSARARVFIELP------LSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKY 842
E+E+ + +RV + +P L++ G P + E E + K+
Sbjct: 753 EEEMDNLK-HSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENE----PETCMVEKMNL 807
Query: 843 EVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNIL 902
V N G S+ + + IM P+ + L+ NIL
Sbjct: 808 TFHVINTGNSMAP--NVSVEIMVPNSFSPQTDKLF----------------------NIL 843
Query: 903 HLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP--VSSAEKKKNITLDCARGTANCVVF 960
+ + + E ++ E+Q+ +M V K L C + +C+ F
Sbjct: 844 DVQTTTGE---CHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNF 900
Query: 961 SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI 1020
C + V +L + E +L+ +RA + + + + L V
Sbjct: 901 LCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVA 960
Query: 1021 PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
V++ +I ++L GL+VL L+ ++WK GFFKR
Sbjct: 961 HVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKR 1007
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 224 bits (572), Expect = 3e-58
Identities = 242/911 (26%), Positives = 394/911 (43%), Gaps = 159/911 (17%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSD-PDQLVYKTLDPADRLPGPAGD 256
Q G +A +S D +++ GA G Y+W G + + P + P
Sbjct: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEP----- 431
Query: 257 LALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL 316
L SYLG++++S + ++ ++AG PR NH G V+I R + + + + LSGE++
Sbjct: 432 --LASYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT-LSGEQI 486
Query: 317 TSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVY-LNQGG--HWAGISPLR 372
S FG L D++ D D L+VGAP + ++E G VYVY LNQ + + P++
Sbjct: 487 GSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIK 546
Query: 373 --LCGSPD--------------SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIY 414
C S + FG ++A + DLN DGF DI +GAP + D G V+IY
Sbjct: 547 QTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIY 606
Query: 415 HGSSLGVVAKPSQVLE--GEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRAR 472
HGS + + +Q + G+ +K FG S+ G +D++G+ D+ +G L A LF +R
Sbjct: 607 HGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-LFWSR 665
Query: 473 PILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA 530
+ V ++ P +++++ NC G +VC++ VCF + + S D + +A
Sbjct: 666 DVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD-VKLKSKE------DTIYEA 718
Query: 531 DTDRRLR----GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKL 586
D R+ Q+ R F +E K Q + TV C F + + D
Sbjct: 719 DLQYRVTLDSLRQISRSFF--SGTQERKVQRNITV-----RKSECTKHSFYMLDK-HDFQ 770
Query: 587 RAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSN 646
++ +TL ++L P P+L+ P++ I F K CG + C S+
Sbjct: 771 DSVRITLDFNLTDPEN------------GPVLDDSLPNSVHEYIPFAKD-CGNKEKCISD 817
Query: 647 LQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGD 706
L L V+ TE L S + L V N D
Sbjct: 818 LSL-------HVATTE----------KDLLIVRSQNDKFNVSLTVKNTK----------D 850
Query: 707 DAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLI 765
A+ + +V +L +SG+ A+ +K C SN N + C++G P ++RG VTF ++
Sbjct: 851 SAYNTRTIVHYSPNLVFSGIEAI---QKDSCESNHN---ITCKVGYPFLRRGEMVTFKIL 904
Query: 766 LSTSGISIETTEL--EVELLLATISEQELHP-------VSARARVFIELPLSIAGMAIPQ 816
T+ L V + L+ S+ E P V+ V E+ L A
Sbjct: 905 FQ-----FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEY 959
Query: 817 QLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLL 876
+ + + S D+G+++ + G + L+I +P+ +NG +L
Sbjct: 960 HISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF--PMPELKLSISFPNMTSNGYPVL 1017
Query: 877 YPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP 936
YP G + C RP+I E P G++
Sbjct: 1018 YPT------GLSSSENANC--RPHIF--------------EDPFSINSGKKMT------- 1048
Query: 937 VSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEV 996
S+ K+ LDC T +C L S D + V +V LW TF++ Y + SL +
Sbjct: 1049 TSTDHLKRGTILDC--NTCKFATITCNLTSSDISQV-NVSLILWKPTFIKSYFS--SLNL 1103
Query: 997 IVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLV 1056
+R + +++ L + + + + D + VP WVILL+ AGLL+L LL+
Sbjct: 1104 TIRGELRSENASLVLSSSNQKRELAIQISKDGLP---GRVPLWVILLSAFAGLLLLMLLI 1160
Query: 1057 LLLWKMGFFKR 1067
L LWK+GFFKR
Sbjct: 1161 LALWKIGFFKR 1171
Score = 57.4 bits (137), Expect = 8e-08
Identities = 38/128 (29%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 23 LVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPG 82
L+ ++ V+FN+DV ++ G +FG++V +Q + W+L+G+P L G
Sbjct: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTV---QQYENEEGKWVLIGSP----LVG 70
Query: 83 QQANRTGGLFACPLSL-EETDCYRVDIDQGADMQK--ESKENQWLGVSVRSQGPGGKIVT 139
Q NRTG ++ CP+ E C ++D+ + E KEN G S P G +
Sbjct: 71 QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFG-STLVTNPNGGFLA 129
Query: 140 CAHRYEAR 147
C Y R
Sbjct: 130 CGPLYAYR 137
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 185 bits (470), Expect = 2e-46
Identities = 226/883 (25%), Positives = 378/883 (42%), Gaps = 133/883 (15%)
Query: 212 LLFGAPGTYNWKG-LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG 270
+LFG G Y+W G +L++ P ++ + D P + A +YLG+S+ S
Sbjct: 386 ILFGMVGAYDWGGSVLWLEGGHRLFPPRMALE-----DEFPPALQNHA--AYLGYSVSSM 438
Query: 271 KGLVRAEELSFVAGAPRANHKGAVVI--LRKDSASRLVPEVMLSGERLTSGFGYSLAVAD 328
L+R F++GAPR H+G V+ L+KD A R+ L GE++ S FG L D
Sbjct: 439 --LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS--LQGEQIGSYFGSELCPLD 494
Query: 329 LNSDGWPD-LIVGAPYFFERQEELGGAVYVYL-NQGGHWAGISPLRLCGSPDSMFGISLA 386
+ DG D L+V AP F Q + G VYVYL Q L+ D+ FG ++
Sbjct: 495 TDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFAMG 554
Query: 387 VLGDLNQDGFPDIAVGAPFDG--DGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSFGYS 442
L DLNQDGF D+AVGAP + G +++YHG+ GV P+Q + ++ + FG S
Sbjct: 555 ALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRS 614
Query: 443 LSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHS 500
+ G LD+DG+ D+ VG+ A+L +RPI+H++ + + P++I + Q +C G +
Sbjct: 615 VDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEA 673
Query: 501 VCVDLRVCFSYIA-VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQAS- 558
VC+ +CF + P + + + A D G + L + + S
Sbjct: 674 VCLTAALCFQVTSRTPGRWDHQFYMRFT--ASLDEWTAGARAAFDGSGQRLSPRRLRLSV 731
Query: 559 GTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL 618
G V + H V + D LR + +T++++L PG P+L
Sbjct: 732 GNVTCEQLHFHVL---------DTSDYLRPVALTVTFALD----NTTKPG-------PVL 771
Query: 619 NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGT-TALF 677
N P++ + + F K CG D C ++L L + MD+ G+ A F
Sbjct: 772 NEGSPTSIQKLVPFSKD-CGPDNECVTDLVL---------------QVNMDIRGSRKAPF 815
Query: 678 ALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLC 737
+ G G ++ + + + ++A+ L ++ +LH + + + +
Sbjct: 816 VVRG----GRRKVLVSTTLENRK-----ENAYNTSLSLIFSRNLHLASLTPQRESPIKVE 866
Query: 738 LSNENASHVECELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQE---LH 793
+ +A C +G+P+ + GA+VTF L S S+ +++ V+L ++ S + L
Sbjct: 867 CAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSL-LSQVFVKLTASSDSLERNGTLQ 925
Query: 794 PVSARARVFIELPLSIAGMAIPQQLFF--SGVVRGERAMQSERDVGSKVKYEVTVSNQGQ 851
+A+ +I+ P LF S + R E VG +++ T+ Q
Sbjct: 926 DNTAQTSAYIQYE--------PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNL 977
Query: 852 SLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDR 911
+ ++ + P G + L QV Q P P +
Sbjct: 978 GCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPV---------- 1027
Query: 912 RRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAA 971
PE+ + R S C V C L +
Sbjct: 1028 ------HPEELQHTNRLNGS----------------------NTQCQVVRCHLGQLAKGT 1059
Query: 972 VLHV-WGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPM 1029
+ V RL ++ F + KSL V+ + T + S+ L L +AS ++ +
Sbjct: 1060 EVSVGLLRLVHNEFFRR-AKFKSLTVVSTFELGTEEGSV--LQLTEASRWSESLLEVVQT 1116
Query: 1030 AVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072
+ + W+++ +VL GLL+LALLV LWK+GFF K PE
Sbjct: 1117 RPIL--ISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPE 1157
Score = 38.1 bits (87), Expect = 0.048
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 9/110 (8%)
Query: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
FNLD G P + FG+SV H Q W+LVGAP G +R G ++
Sbjct: 23 FNLDEHHPRLFPGPPEAEFGYSVLQH---VGGGQRWMLVGAP----WDGPSGDRRGDVYR 75
Query: 94 CPL-SLEETDCYRVDI-DQGADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
CP+ C + + D N LG+S+ G + CA
Sbjct: 76 CPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACA 125
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 162 bits (409), Expect = 2e-39
Identities = 230/915 (25%), Positives = 376/915 (41%), Gaps = 169/915 (18%)
Query: 211 YLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG 270
+ + GA G +W G D D + + L P R YLG+++
Sbjct: 362 HAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRA----------GYLGYTVT-- 409
Query: 271 KGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYSLAVAD 328
L ++ S +A GAPR H G V++ ++ +V + G ++ S FG L D
Sbjct: 410 -WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVD 468
Query: 329 LNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMFGISLA 386
++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P FG ++
Sbjct: 469 VDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAIT 526
Query: 387 VLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSFGYSLS 444
L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ FG S+
Sbjct: 527 ALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 586
Query: 445 GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHS---- 500
G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+ S
Sbjct: 587 GVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMK 645
Query: 501 VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLEEPKHQ 556
V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 646 EGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSM 705
Query: 557 ASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAPGQGLP 612
+ C D F V+D + I V+L++SL TPR +R A G+ +P
Sbjct: 706 S-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR-AQGKDIP 751
Query: 613 PVAPILNAHQPS--TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV 670
P+ +PS ++ EI F K CGEDK C++NL++ F P
Sbjct: 752 PIL------RPSLHSETWEIPFEKN-CGEDKKCEANLRV------------SFSPARSRA 792
Query: 671 DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD 730
TA +LS +EL ++NL +DA+ QL + P L + V L
Sbjct: 793 LRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKVEML- 835
Query: 731 PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 790
K +Q+ +S E E LL +S
Sbjct: 836 ------------------------KPHSQIP---------VSCEELPEESRLLSRALSCN 862
Query: 791 ELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQG 850
+ P+ AG ++ Q+ F+ +V E + VT +N+
Sbjct: 863 ------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTCNNED 904
Query: 851 QSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH------- 903
L SA I +LYP+ + ++ + +P+ +H
Sbjct: 905 SDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQ 954
Query: 904 --LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTA 955
+ D LE P + P Q PV + D A
Sbjct: 955 VRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCL 1014
Query: 956 NCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRD 1015
+F CP+ F + ++ V G L + E A + +I+ SS +
Sbjct: 1015 PGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFHLYGS 1070
Query: 1016 ASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATV 1075
+++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR +
Sbjct: 1071 NASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1127
Query: 1076 PQYHAVKIPREDRQQ 1090
+ IP ED +Q
Sbjct: 1128 GRGVPNGIPAEDSEQ 1142
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 160 bits (404), Expect = 8e-39
Identities = 229/915 (25%), Positives = 375/915 (40%), Gaps = 170/915 (18%)
Query: 211 YLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG 270
+ + GA G +W G D D + + L P R YLG+++
Sbjct: 279 HAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRA----------GYLGYTVT-- 326
Query: 271 KGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYSLAVAD 328
L ++ S +A GAPR H G V++ ++ +V + G ++ S FG L D
Sbjct: 327 -WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVD 385
Query: 329 LNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMFGISLA 386
++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P FG ++
Sbjct: 386 VDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAIT 443
Query: 387 VLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSFGYSLS 444
L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ FG S+
Sbjct: 444 ALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 503
Query: 445 GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHS---- 500
G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+ S
Sbjct: 504 GVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMK 562
Query: 501 VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLEEPKHQ 556
V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 563 EGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSM 622
Query: 557 ASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAPGQGLP 612
+ C D F V+D + I V+L++SL TPR +R G+ +P
Sbjct: 623 S-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRA--GKDIP 667
Query: 613 PVAPILNAHQPS--TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV 670
P+ +PS ++ EI F K CGEDK C++NL++ F P
Sbjct: 668 PIL------RPSLHSETWEIPFEKN-CGEDKKCEANLRV------------SFSPARSRA 708
Query: 671 DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD 730
TA +LS +EL ++NL +DA+ QL + P L + V L
Sbjct: 709 LRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKVEML- 751
Query: 731 PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 790
K +Q+ +S E E LL +S
Sbjct: 752 ------------------------KPHSQIP---------VSCEELPEESRLLSRALSCN 778
Query: 791 ELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQG 850
+ P+ AG ++ Q+ F+ +V E + VT +N+
Sbjct: 779 ------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTCNNED 820
Query: 851 QSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH------- 903
L SA I +LYP+ + ++ + +P+ +H
Sbjct: 821 SDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQ 870
Query: 904 --LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTA 955
+ D LE P + P Q PV + D A
Sbjct: 871 VRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCL 930
Query: 956 NCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRD 1015
+F CP+ F + ++ V G L + E A + +I+ SS +
Sbjct: 931 PGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFHLYGS 986
Query: 1016 ASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATV 1075
+++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR +
Sbjct: 987 NASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1043
Query: 1076 PQYHAVKIPREDRQQ 1090
+ IP ED +Q
Sbjct: 1044 GRGVPNGIPAEDSEQ 1058
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 156 bits (395), Expect = 9e-38
Identities = 168/654 (25%), Positives = 288/654 (44%), Gaps = 75/654 (11%)
Query: 164 FVLSQDLAIRDELDG-GEWKFC-EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYN 221
F ++ + A++D +D G+ F EG + FG T + +L GA G Y+
Sbjct: 330 FNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYD 389
Query: 222 WKG-LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELS 280
W G +L T+ P + Y P + A YLG+++ S + +
Sbjct: 390 WNGAVLKETSAGKVIPLRESYLKEFPEELKNHGA-------YLGYTVTSV--VSSRQGRV 440
Query: 281 FVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIV 339
+VAGAPR NH G V++ + L + G+++ S FG + D++ DG D L+V
Sbjct: 441 YVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLV 500
Query: 340 GAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGS-PDSMFGISLAVLGDLNQDGFPD 398
GAP +F E G VYVY + + L+ S ++ FG S+A + DLNQD + D
Sbjct: 501 GAPMYFNEGRE-RGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYND 559
Query: 399 IAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGE--AVGIKSFGYSLSGSLDMDGNQY 454
+ VGAP + + G ++I+HG ++ P Q + A G++ FG S+ G LD++ +
Sbjct: 560 VVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGL 619
Query: 455 PDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYI 512
DL VG+L + +L+ +RP++ ++ + P I++ +C +G + C+ +CF+ I
Sbjct: 620 IDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPI 678
Query: 513 -AVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVC 571
P + TV + Y D R PR +L+E + + L +C
Sbjct: 679 FLAPHFQTTTVGIRYNATMDE----RRYTPRA-----HLDEGGDRFTNRAVLLSSGQELC 729
Query: 572 GDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIH 631
F + + D ++ + ++ YSL+ P P+L+ P+T R +
Sbjct: 730 ERINFHVLDTA-DYVKPVTFSVEYSLED------------PDHGPMLDDGWPTTLRVSVP 776
Query: 632 FLKQGCGEDKICQSNLQL-------VRARFCTRV-----SDTEFQPLPMDVDGTTALFAL 679
F GC ED+ C +L L +C RV D L D TT
Sbjct: 777 FW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFD---TTVFIIE 832
Query: 680 SGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL-CL 738
S + + +E + N G++A+ L + +L ++ + + ++ + C+
Sbjct: 833 STRQRVAVEATLEN----------RGENAYSTVLNISQSANLQFASLIQKEDSDGSIECV 882
Query: 739 SNENASHVE-CELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQ 790
+ E + C + P R A+V F L S SI LE+EL + S +
Sbjct: 883 NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNE 935
Score = 48.1 bits (113), Expect = 5e-05
Identities = 21/34 (61%), Positives = 28/34 (82%)
Query: 1036 VPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1069
VP W+I+ + L GLL+LALLVL LWK+GFF+ A+
Sbjct: 1140 VPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
Score = 36.6 bits (83), Expect = 0.14
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
FN+D G + FG++V H WL+VGAP L G Q +TG ++
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQH---DISGNKWLVVGAP--LETNGYQ--KTGDVYK 75
Query: 94 CPLSLEETDCYRVDIDQ-GADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
CP+ +C ++++ + E K+N LG+S+ + + C+
Sbjct: 76 CPVI--HGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACS 122
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 151 bits (381), Expect = 4e-36
Identities = 241/911 (26%), Positives = 367/911 (40%), Gaps = 169/911 (18%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPD-QLVYKTLDPADRLPGPAGD 256
Q+G +A F+PD L GA G++ W G F+ + S + + +D D
Sbjct: 353 QEGFSAVFTPDGPVL--GAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMRD-------- 402
Query: 257 LALNSYLGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVILRKDSAS-RLVPEVMLSG 313
SYLG+S + KG+ S V GAPR H G VI + S R+ EV +G
Sbjct: 403 ----SYLGYSTELALWKGVQ-----SLVLGAPRYQHTGKAVIFTQVSRQWRMKAEV--TG 451
Query: 314 ERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQGGH--WAGIS 369
++ S FG SL D++SDG DL+ +GAP+++E+ GG V V L +G W
Sbjct: 452 TQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGWRRWWCDAV 509
Query: 370 PLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKP-- 425
G P FG +L VLGD+N D D+ +GAP + + G V+++HG LG P
Sbjct: 510 LYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHG-VLGPSISPSH 568
Query: 426 SQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSI 483
SQ + G + ++ FG +LSG D+ + DL VG+ +L R RP+L V +
Sbjct: 569 SQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQ-VLLLRTRPVLWVGVSMQF 627
Query: 484 APRSIDLEQPNC---AGGHSVCVDLRVCFSYIAVPS-------SYSPTVALDYVLDADTD 533
P I C V +C YI S +V LD LD
Sbjct: 628 IPAEIPRSAFECREQVVSEQTLVQSNICL-YIDKRSKNLLGSRDLQSSVTLDLALDPG-- 684
Query: 534 RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 593
RL PR TF +E K+++ V + C + L V+D + I + L
Sbjct: 685 -RLS---PRATF-----QETKNRSLSRVRVLGLKAH-CENFNLLLPSCVEDSVTPITLRL 734
Query: 594 SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 653
+++L P + P+L A A + F ++ CG D ICQ NL
Sbjct: 735 NFTLV------GKPLLAFRNLRPMLAADAQRYFTASLPF-EKNCGADHICQDNL------ 781
Query: 654 FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 713
+ G +L S + E+MV N DG+D++ +
Sbjct: 782 -----------GISFSFPGLKSLLVGSNLE-LNAEVMVWN----------DGEDSYGTTI 819
Query: 714 LVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVECELGNPMKR-GAQVTFY 763
P L Y V R+L + ++ C + + + R GAQ+TF
Sbjct: 820 TFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITF- 878
Query: 764 LILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGV 823
L+T +S + + LL A +S + P +++ +ELP+ A +
Sbjct: 879 --LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSS--HEQF 934
Query: 824 VRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEI-ANGKWLLYPMQVE 882
+ +SE + V+N GQ R L +N P E+ W M VE
Sbjct: 935 TKYLNFSESEEKESHVAMHRYQVNNLGQ--RDL-PVSINFWVPVELNQEAVW----MDVE 987
Query: 883 LEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEK 942
+ Q P + CS ++ PP A
Sbjct: 988 VSHPQNPSLR--CS----------------SEKIAPPASD---------------FLAHI 1014
Query: 943 KKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVI 997
+KN LDC+ A C+ F C P +S + G L W L+ K + V+
Sbjct: 1015 QKNPVLDCS--IAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVV 1067
Query: 998 VRANITVKSSI-KNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLV 1056
A IT +S+ L ++A L+ V P +I+ + + GLL+LAL+
Sbjct: 1068 SVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKV---HNPTPLIVGSSIGGLLLLALIT 1124
Query: 1057 LLLWKMGFFKR 1067
+L+K+GFFKR
Sbjct: 1125 AVLYKVGFFKR 1135
Score = 36.6 bits (83), Expect = 0.14
Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 22/122 (18%)
Query: 21 SLLVELLFSRAVAFNLDV--MGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQAL 78
+LL+ + ++ FNLD + A R + FG SV + SW++VGAPQ +
Sbjct: 7 ALLLFTALATSLGFNLDTEELTAFRVDSAG---FGDSVVQYAN------SWVVVGAPQKI 57
Query: 79 ALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIV 138
AN+TGGL+ C S + + + A N LG+S+ S +++
Sbjct: 58 T----AANQTGGLYQCGYSTGACEPIGLQVPPEA-------VNMSLGLSLASTTSPSQLL 106
Query: 139 TC 140
C
Sbjct: 107 AC 108
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 150 bits (378), Expect = 9e-36
Identities = 137/463 (29%), Positives = 216/463 (46%), Gaps = 60/463 (12%)
Query: 208 DSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSI 267
D +L GA G ++W G + + S L AD + A SYLG+++
Sbjct: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAAD------AEAAQYSYLGYAV 465
Query: 268 DSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVA 327
L + LS++AGAPR H GAV L+K+ V L GE++ S FG L
Sbjct: 466 AV---LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPV-LEGEQMGSYFGSELCPV 521
Query: 328 DLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSP---DSMFGI 383
D++ DG D L+V AP++ EE G VYVY + L G P ++ FG
Sbjct: 522 DIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILSGHPGFTNARFGF 579
Query: 384 SLAVLGDLNQDGFPDIAVGAPFDG--------DGKVFIYHGSSLGVVAKPSQVLEGEAV- 434
++A +GDL+QD D+A+GAP +G G V+IY+G G+ A PSQ + V
Sbjct: 580 AMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVA 639
Query: 435 -GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQP 493
G++ FG S++G D+ G+ D+ VG+L AV+FR+RP++ + ++ P ++ +
Sbjct: 640 PGLQYFGMSMAGGFDISGDGLADITVGTLGQ-AVVFRSRPVVRLKVSMAFTPSALPI--- 695
Query: 494 NCAGGHSVCVDLRVCFSYIAVPSSYSP---TVALDYVLDADTDR-RLRGQVPRVTFLSRN 549
G + V++R+CF +V ++ L++ LD D + R R Q V
Sbjct: 696 ----GFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGC 751
Query: 550 LEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN---VKDKLRAIVVTLSYSLQTPRLRRQA 606
L E +SG+ ++C D + E +D V +SY LQTP +
Sbjct: 752 LRE---WSSGS--------QLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDH 800
Query: 607 PGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 649
P PIL+ + ++ + ++ C C + LQL
Sbjct: 801 P-------QPILDRYTEPFAIFQLPY-EKACKNKLFCVAELQL 835
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 17 YLFGSLLVELLFSRAVAFNLDVMGA-LRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAP 75
+LF +LL + AFN+DV L +G G+ F S LH+ Q+WLLV +P
Sbjct: 2 WLFHTLLCIASLALLAAFNVDVARPWLTPKG--GAPFVLSSLLHQDPSTN-QTWLLVTSP 58
Query: 76 QALALPGQQANRTGGLFACPLSLEETDCYRVD 107
+ PG L C L +E C+ V+
Sbjct: 59 RTKRTPGP-------LHRCSLVQDEILCHPVE 83
Score = 32.0 bits (71), Expect = 3.4
Identities = 13/28 (46%), Positives = 22/28 (78%)
Query: 1040 VILLAVLAGLLVLALLVLLLWKMGFFKR 1067
+I+ + GLLVL +++++L+K GFFKR
Sbjct: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 149 bits (375), Expect = 2e-35
Identities = 157/622 (25%), Positives = 268/622 (43%), Gaps = 84/622 (13%)
Query: 185 EGRPQGHEQFGF--CQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYK 242
EG QG + F Q G +A +S + L+ GA G + W G T + + L++
Sbjct: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSG----TIVQKTSHGHLIF- 419
Query: 243 TLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSA 302
P D +SYLG+S+ + + E FVAGAPRAN+ G +V+ +
Sbjct: 420 ---PKQAFDQILQDRNHSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYSVNEN 473
Query: 303 SRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQ 361
+ G+++ S FG L D++ D D L+VGAP + ++ G VY++ +
Sbjct: 474 GNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIK 533
Query: 362 GG----HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD--GDGKVFIYH 415
G H P G ++ FG ++A L D+N DGF D+ VG+P + G V+IY+
Sbjct: 534 EGILGQHQFLEGPE---GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYN 590
Query: 416 GSSLGVVAKPSQVLEGEAVGIKS----FGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRA 471
G + K SQ + G +S FG SL G D++G+ D+ +G+ L+ +
Sbjct: 591 GHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLW-S 649
Query: 472 RPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDAD 531
+ I V+ E S P I L N + L++CFS P+ + VA+ Y + D
Sbjct: 650 QSIADVAIEASFTPEKITLVNKNAQ------IILKLCFSAKFRPTKQNNQVAIVYNITLD 703
Query: 532 TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVV 591
D G RVT SR L + ++ + + C + + +QE D + ++ +
Sbjct: 704 AD----GFSSRVT--SRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDL 756
Query: 592 TLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL-V 650
+ SL+ P +P L A+ + + I F K CGED +C S+L L V
Sbjct: 757 RVDISLEN------------PGTSPALEAYSETAKVFSIPFHKD-CGEDGLCISDLVLDV 803
Query: 651 RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE 710
R ++ + QP + F+++ + + A+
Sbjct: 804 R-----QIPAAQEQPFIVSNQNKRLTFSVT--------------------LKNKRESAYN 838
Query: 711 AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLILSTS 769
++V ++L ++ + C + V C++G P +KR QVTF +
Sbjct: 839 TGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTI---NF 895
Query: 770 GISIETTELEVELLLATISEQE 791
+++ + + L +SE +
Sbjct: 896 DFNLQNLQNQASLSFQALSESQ 917
Score = 53.1 bits (126), Expect = 1e-06
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 954 TANCVVFSCPLYSFDRAA--VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 1011
TA+C +C L ++V R+WN TF S +++++ A I + +
Sbjct: 1052 TASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS--STFQTVQLTAAAEINTYNP-EIY 1108
Query: 1012 MLRDASTVIPVMVYL-DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
++ D + IP+M+ D A V GV I+ +++AG+L+L LV +LWK+GFFKR
Sbjct: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV----IIGSIIAGILLLLALVAILWKLGFFKR 1161
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 138 bits (347), Expect = 3e-32
Identities = 205/902 (22%), Positives = 357/902 (39%), Gaps = 149/902 (16%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDL 257
Q+G +AA + S+ L G+Y+W G +F+ S + + T +D
Sbjct: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYT--SKEKSTFINMTRVDSDMN------- 400
Query: 258 ALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLT 317
++YLG++ ++R S V GAPR H G V + R+++ + G ++
Sbjct: 401 --DAYLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANVKGTQIG 454
Query: 318 SGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY---LNQGGHWAGISPLR- 372
+ FG SL D++S+G DL+ +GAP+++E+ GG V V Q W + L
Sbjct: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQCDAVLYG 512
Query: 373 LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAKPSQVL 429
G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+ SQ +
Sbjct: 513 EQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRI 572
Query: 430 EGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRS 487
G + ++ FG SLSG D+ + DL VG+ +L R++P+L V + PR
Sbjct: 573 AGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIMEFNPRE 631
Query: 488 IDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRG 538
+ C AG VC+ ++ V D LD+ R
Sbjct: 632 VARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-----RP 686
Query: 539 QVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ 598
V ++N + Q G + C QL ++D + IV+ L++SL
Sbjct: 687 HSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRLNFSLV 739
Query: 599 TPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 658
P + P+L A + ++ CG D ICQ +L +
Sbjct: 740 ------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT-------- 784
Query: 659 SDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLP 718
F + +D + G + + V N DG+D++ Q+ P
Sbjct: 785 ----FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQVTFFFP 824
Query: 719 DSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVTFYLIL 766
L Y V L +++ L+ E+AS E C + +P+ ++VTF +
Sbjct: 825 LDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITF 884
Query: 767 STSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRG 826
+ +L LL A ++ + P + + +ELP+ A+ + GV
Sbjct: 885 DVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSHGVSTK 938
Query: 827 ERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGG 886
+ + ++++ VSN GQ + F L P+++
Sbjct: 939 YLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL----- 978
Query: 887 QGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI 946
+ + RP + + S +E P AE +K
Sbjct: 979 ----NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAELRKAP 1019
Query: 947 TLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKS 1006
++C+ + P + + G L +++ ++ L ++ A I
Sbjct: 1020 VVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFND 1077
Query: 1007 SIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFF 1065
S+ L+ + V ++P V P +I+ + + GLL+LAL+ L+K+GFF
Sbjct: 1078 SVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALYKLGFF 1134
Query: 1066 KR 1067
KR
Sbjct: 1135 KR 1136
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 137 bits (345), Expect = 6e-32
Identities = 206/901 (22%), Positives = 359/901 (39%), Gaps = 148/901 (16%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDL 257
Q+G +AA + S+ L G+Y+W G +F+ S + + T +D
Sbjct: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYT--SKEKSTFINMTRVDSDMN------- 400
Query: 258 ALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLT 317
++YLG++ ++R S V GAPR H G V + R+++ + G ++
Sbjct: 401 --DAYLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANVKGTQIG 454
Query: 318 SGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGISPLR-L 373
+ FG SL D++S+G DL+ +GAP+++E+ GG V V L +G W + L
Sbjct: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCDAVLYGE 512
Query: 374 CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAKPSQVLE 430
G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+ SQ +
Sbjct: 513 QGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIA 572
Query: 431 GEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 488
G + ++ FG SLSG D+ + DL VG+ +L R++P+L V + PR +
Sbjct: 573 GSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIMEFNPREV 631
Query: 489 DLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQ 539
C AG VC+ ++ V D LD+ R
Sbjct: 632 ARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-----RPH 686
Query: 540 VPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQT 599
V ++N + Q G + C QL ++D + IV+ L++SL
Sbjct: 687 SRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRLNFSLV- 738
Query: 600 PRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVS 659
P + P+L A + ++ CG D ICQ +L +
Sbjct: 739 -----GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--------- 783
Query: 660 DTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPD 719
F + +D + G + + V N DG+D++ Q+ P
Sbjct: 784 ---FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQVTFFFPL 824
Query: 720 SLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVTFYLILS 767
L Y V L +++ L+ E+AS E C + +P+ ++VTF +
Sbjct: 825 DLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFD 884
Query: 768 TSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGE 827
+ +L LL A ++ + P + + +ELP+ A+ + GV
Sbjct: 885 VDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSHGVSTKY 938
Query: 828 RAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQ 887
+ + ++++ VSN GQ + F L P+++
Sbjct: 939 LNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL------ 977
Query: 888 GPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT 947
+ + RP + + S +E P AE +K
Sbjct: 978 ---NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAELRKAPV 1019
Query: 948 LDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSS 1007
++C+ + P + + G L +++ ++ L ++ A I S
Sbjct: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDS 1077
Query: 1008 IKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFK 1066
+ L+ + V ++P V P +I+ + + GLL+LAL+ L+K+GFFK
Sbjct: 1078 VFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALYKLGFFK 1134
Query: 1067 R 1067
R
Sbjct: 1135 R 1135
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 129 bits (323), Expect = 2e-29
Identities = 222/929 (23%), Positives = 377/929 (40%), Gaps = 183/929 (19%)
Query: 185 EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPD-QLVYKT 243
+ R Q Q+G + A + D +L GA G+++W G F+ + S + +
Sbjct: 339 QSRASSSFQHEMSQEGFSTALTMDGLFL--GAVGSFSWSGGAFLYPPNMSPTFINMSQEN 396
Query: 244 LDPADRLPGPAGDLALNSYLGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVILRKDS 301
+D D SYLG+S + KG+ + V GAPR H G VI + S
Sbjct: 397 VDMRD------------SYLGYSTELALWKGVQ-----NLVLGAPRYQHTGKAVIFTQVS 439
Query: 302 AS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYL 359
R EV +G ++ S FG SL D++SDG DLI +GAP+++E+ GG V V
Sbjct: 440 RQWRKKAEV--TGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCP 495
Query: 360 NQGGH--WAGISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIY 414
G W + LR G P FG +L VLGD+N+D D+A+GAP + + G V+++
Sbjct: 496 LPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLF 555
Query: 415 HGSS-LGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRA 471
HG+S G+ SQ + + ++ FG +LSG D+ + DL VG+ +L R+
Sbjct: 556 HGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQ-VLLLRS 614
Query: 472 RPILHVSHEVSIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTV 522
P+L V + +P + C AG +VC+ ++ S + +V
Sbjct: 615 LPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQK--SSLDQLGDIQSSV 672
Query: 523 ALDYVLDAD--TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQE 580
D LD T R + + T R T+ L C L +
Sbjct: 673 RFDLALDPGRLTSRAIFNETKNPTLTRRK----------TLGLGIH----CETLKLLLPD 718
Query: 581 NVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGED 640
V+D + I++ L++SL +R P + P+L A + F ++ CG+D
Sbjct: 719 CVEDVVSPIILHLNFSL----VREPIPSP--QNLRPVLAVGSQDLFTASLPF-EKNCGQD 771
Query: 641 KICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQ 700
+C+ +L + + + L L+ + L ++VT +
Sbjct: 772 GLCEGDLGVTLS--------------------FSGLQTLTVGSSLELNVIVTVWNA---- 807
Query: 701 PQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVECELG 751
G+D++ + + P L + V AL A + + +E C +
Sbjct: 808 ----GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVN 863
Query: 752 NPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIA 810
+P+ G+ TF + T +S + T + L+ A+ S + S++A +ELP+ A
Sbjct: 864 HPIFHEGSNGTF---IVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELPVKYA 920
Query: 811 GMAI-----PQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMW 865
+ +F+ E+ M+ + ++ V+N Q + F W
Sbjct: 921 VYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNLSQRDLAISINF----W 969
Query: 866 PHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEP- 924
+ NG + DV +E P Q P
Sbjct: 970 VPVLLNG----------------------------VAVWDV--------VMEAPSQSLPC 993
Query: 925 -GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWGRL-- 979
ER+ P S + + ++ LDC+ A+C+ F C P +S + G L
Sbjct: 994 VSERKPPQHSDF---LTQISRSPMLDCS--IADCLQFRCDVPSFSVQEELDFTLKGNLSF 1048
Query: 980 -WNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPW 1038
W L+ K + V+ A IT +S+ + + + + M + V +P
Sbjct: 1049 GWVRETLQ-----KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIP- 1102
Query: 1039 WVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
+I+ + + LL+LAL+ L+K+GFFKR
Sbjct: 1103 -IIMGSSVGALLLLALITATLYKLGFFKR 1130
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 71.2 bits (173), Expect = 5e-12
Identities = 54/158 (34%), Positives = 79/158 (50%), Gaps = 22/158 (13%)
Query: 321 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRL------- 373
G+++ ADLN DG DL+VGAP + G VY+ G+ G+ P+ L
Sbjct: 382 GWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIY---GNDLGLPPVDLDLDKEAH 438
Query: 374 ----CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD------GKVFIYHGSSLGVVA 423
P FG +LAVL D N DG PD+AVGAP G G V++Y GS G ++
Sbjct: 439 RILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMS 497
Query: 424 KPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGS 461
+ + G++L + D++G+ PDL++GS
Sbjct: 498 SSPNITISCQDIYCNLGWTLLAA-DVNGDSEPDLVIGS 534
Score = 65.1 bits (157), Expect = 4e-10
Identities = 59/164 (35%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 310 MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGIS 369
+L G + + FG +LAV D N DG PDL VGAP Q GAVYVY S
Sbjct: 440 ILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSS 499
Query: 370 PLRLCGSPDSMFGISLAVL-GDLNQDGFPDIAVGAPF-DGDGK-----VFIYHGSSLG-- 420
P D + +L D+N D PD+ +G+PF G GK Y G SL
Sbjct: 500 PNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDK 559
Query: 421 ---VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGS 461
V + + GE FGYSL G + +D LLVGS
Sbjct: 560 EKLNVEAANWTVRGEE-DFSWFGYSLHG-VTVDNRTL--LLVGS 599
Score = 41.6 bits (96), Expect = 0.004
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 284 GAPRANHKGAVVIL--RKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGA 341
G+ + +KGAV + K P + +S + + G++L AD+N D PDL++G+
Sbjct: 475 GSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGS 534
Query: 342 PY 343
P+
Sbjct: 535 PF 536
Score = 33.5 bits (75), Expect = 1.2
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 254 AGDLALNSYLGFSIDSGKGLVRAE-ELSFVAGAPRANHKGAV----VILRKDSASRLV-- 306
+GD A+ LG S+ SG L+ + + GAP + V V L + A+R+
Sbjct: 639 SGDKAMGK-LGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTVTLHQGGATRMYAL 697
Query: 307 -----PEVM--LSGERLTSGFGYSLAVADLNSDGWPDLIVGAP 342
P ++ SG+R S FG L ++DL+ DG ++I+ AP
Sbjct: 698 TSDAQPLLLSTFSGDRRFSRFGGVLHLSDLDDDGLDEIIMAAP 740
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 46.6 bits (109), Expect = 1e-04
Identities = 116/469 (24%), Positives = 177/469 (37%), Gaps = 86/469 (18%)
Query: 634 KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 693
++ CG D ICQ NL + G +L S + E+MV N
Sbjct: 17 EKNCGADHICQDNLGI-----------------SFSFPGLKSLLVGSNLE-LNAEVMVWN 58
Query: 694 LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENAS 744
DG+D++ + P L Y V R+L + ++
Sbjct: 59 ----------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTW 108
Query: 745 HVECELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 803
C + + + RG AQ+TF L+T +S + + LL A +S + P +++ +
Sbjct: 109 STSCRINHLIFRGGAQITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQL 165
Query: 804 ELPLSIAGMAI-------PQQLFFSGVVRGER--AMQSERDVGSKVKYEVTVSNQGQSLR 854
ELP+ A + + L FS E AM + G V+N GQ R
Sbjct: 166 ELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQ--R 223
Query: 855 TLGSAFLNIMWPHEI-ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRR 913
L + +N P E+ W M VE+ Q P C + +DS
Sbjct: 224 DLPVS-INFWVPVELNQEAVW----MDVEVSHPQVPKD---CMWLLHECPFYLDSLCPMW 275
Query: 914 RELEPPEQ-------QEPGERQEPSMSWWPVSS--AEKKKNITLDCARGTANCVVFSC-- 962
P E Q P R P S A +KN LDC+ A C+ F C
Sbjct: 276 VPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS--IAGCLRFRCDV 333
Query: 963 PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVIVRANITVKSSI-KNLMLRDAST 1018
P +S + G L W L+ K + V+ A IT +S+ L ++A
Sbjct: 334 PSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVVSVAEITFDTSVYSQLPGQEAFM 388
Query: 1019 VIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
L+ V P +I+ + + GLL+LAL+ +L+K+GFFKR
Sbjct: 389 RAQTTTVLEKYKVHN---PTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434
>gi|32967597 pyruvate kinase, liver and RBC isoform 2 [Homo sapiens]
Length = 543
Score = 32.0 bits (71), Expect = 3.4
Identities = 23/95 (24%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
Query: 71 LVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQ-----KESKENQWLG 125
++G+ + + LPG Q + G LS ++ R ++ G D+ +++ + +
Sbjct: 214 VLGSRKGVNLPGAQVDLPG------LSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVR 267
Query: 126 VSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMI 160
++ +G G KI++ +E +R D+ILE D I
Sbjct: 268 AALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI 302
>gi|10835121 pyruvate kinase, liver and RBC isoform 1 [Homo sapiens]
Length = 574
Score = 32.0 bits (71), Expect = 3.4
Identities = 23/95 (24%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
Query: 71 LVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQ-----KESKENQWLG 125
++G+ + + LPG Q + G LS ++ R ++ G D+ +++ + +
Sbjct: 245 VLGSRKGVNLPGAQVDLPG------LSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVR 298
Query: 126 VSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMI 160
++ +G G KI++ +E +R D+ILE D I
Sbjct: 299 AALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI 333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,413,446
Number of Sequences: 37866
Number of extensions: 2356862
Number of successful extensions: 6125
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 5737
Number of HSP's gapped (non-prelim): 95
length of query: 1137
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1024
effective length of database: 13,968,660
effective search space: 14303907840
effective search space used: 14303907840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.