Guide to the Human Genome
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Name: PKLR Sequence: fasta or formatted (543aa) NCBI GI: 32967597
Description:

pyruvate kinase, liver and RBC isoform 2

Referenced in:

Glycolysis

Other entries for this name:
alt prot [574aa] pyruvate kinase, liver and RBC isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.4         62           3
 C cysteine            1.3          7           2
 D aspartate           4.4         24           2
 E glutamate           7.0         38           2
 F phenylalanine       3.1         17           2
 G glycine             8.8         48           2
 H histidine           1.8         10           1
 I isoleucine          6.8         37           2
 K lysine              3.3         18           1
 L leucine             8.1         44           2
 M methionine          2.2         12           2
 N asparagine          2.4         13           1
 P proline             5.0         27           2
 Q glutamine           3.7         20           4
 R arginine            7.7         42           2
 S serine              5.9         32           1
 T threonine           4.4         24           3
 V valine             10.3         56           2
 W tryptophan          0.6          3           1
 Y tyrosine            1.7          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pyruvate kinase, liver and RBC isoform 2 
PKLR                  0.996   pyruvate kinase, liver and RBC isoform 1 
PKM2                  0.716   pyruvate kinase, muscle isoform M2 
PKM2                  0.696   pyruvate kinase, muscle isoform M1 
PKM2                  0.696   pyruvate kinase, muscle isoform M1 
LOC652797             0.426   PREDICTED: similar to pyruvate kinase, muscle [Homo...
ITGA7                 0.007   integrin alpha 7 isoform 1 precursor 
ITGA7                 0.007   integrin alpha 7 isoform 2 precursor 
GRIP2                 0.005   glutamate receptor interacting protein 2 
ARID2                 0.005   AT rich interactive domain 2 (ARID, RFX-like) 
CDK5RAP2              0.005   CDK5 regulatory subunit associated protein 2 isoform...
CDK5RAP2              0.005   CDK5 regulatory subunit associated protein 2 isoform...
LOC100133305          0.005   PREDICTED: hypothetical protein 
LOC100133305          0.005   PREDICTED: hypothetical protein 
THOC4                 0.005   THO complex 4 
LOC647546             0.005   PREDICTED: hypothetical protein 
LOC729154             0.004   PREDICTED: hypothetical protein 
LOC729154             0.004   PREDICTED: hypothetical protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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