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Search of human proteins with 222352149
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
(648 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 1306 0.0
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 761 0.0
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 343 3e-94
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 342 6e-94
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 335 6e-92
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 335 6e-92
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 294 2e-79
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 294 2e-79
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 292 6e-79
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 274 2e-73
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 273 4e-73
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 273 4e-73
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 273 4e-73
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 272 6e-73
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 272 6e-73
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 247 3e-65
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 220 3e-57
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 213 6e-55
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 211 2e-54
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 208 1e-53
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 203 4e-52
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 203 4e-52
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 202 8e-52
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 199 5e-51
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 199 7e-51
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 198 1e-50
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 196 4e-50
gi|13129006 nucleolar protein GU2 [Homo sapiens] 196 7e-50
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 193 4e-49
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 183 4e-46
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 1306 bits (3381), Expect = 0.0
Identities = 648/648 (100%), Positives = 648/648 (100%)
Query: 1 MSHHGGAPKASTWVVASRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEA 60
MSHHGGAPKASTWVVASRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEA
Sbjct: 1 MSHHGGAPKASTWVVASRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEA 60
Query: 61 VAAGHEELPLCFALKSHFVGAVIGRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAM 120
VAAGHEELPLCFALKSHFVGAVIGRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAM
Sbjct: 61 VAAGHEELPLCFALKSHFVGAVIGRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAM 120
Query: 121 QTKAKAVIDNFVKKLEENYNSECGIDTAFQPSVGKDGSTDNNVVAGDRPLIDWDQIREEG 180
QTKAKAVIDNFVKKLEENYNSECGIDTAFQPSVGKDGSTDNNVVAGDRPLIDWDQIREEG
Sbjct: 121 QTKAKAVIDNFVKKLEENYNSECGIDTAFQPSVGKDGSTDNNVVAGDRPLIDWDQIREEG 180
Query: 181 LKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPT 240
LKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPT
Sbjct: 181 LKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPT 240
Query: 241 CTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPG 300
CTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPG
Sbjct: 241 CTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPG 300
Query: 301 FIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIE 360
FIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIE
Sbjct: 301 FIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIE 360
Query: 361 ELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPD 420
ELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPD
Sbjct: 361 ELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPD 420
Query: 421 RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTF 480
RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTF
Sbjct: 421 RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTF 480
Query: 481 LQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRI 540
LQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRI
Sbjct: 481 LQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRI 540
Query: 541 LIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVAS 600
LIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVAS
Sbjct: 541 LIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVAS 600
Query: 601 ELINILERANQSIPEELVSMAERFKAHQQKREMERKMERPQGRPKKFH 648
ELINILERANQSIPEELVSMAERFKAHQQKREMERKMERPQGRPKKFH
Sbjct: 601 ELINILERANQSIPEELVSMAERFKAHQQKREMERKMERPQGRPKKFH 648
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 761 bits (1964), Expect = 0.0
Identities = 387/626 (61%), Positives = 485/626 (77%), Gaps = 5/626 (0%)
Query: 26 APERRPAEELNRTGPEGYSV--GRGGRWRGTSRPPEAVAAGHEELPLCFALKSHFVGAVI 83
APE + AE R + V RG W G AAG E PLCF +K++ VG VI
Sbjct: 5 APEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMVGVVI 64
Query: 84 GRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAMQTKAKAVIDNFVKKLEENYNSEC 143
G GSKIK++Q +TNT IQII + E+ V+IFG++ M+ KAKA I+ ++K +E+YNSE
Sbjct: 65 GYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRK-QESYNSES 123
Query: 144 GIDTAF-QPSVGKDGSTDNNVVAGDRPLIDWDQIREEGLKWQKTKWADLPPIKKNFYKES 202
+D A Q +G++ N++V PL +WD+IR ++ +K KWADLPP+KKNFY ES
Sbjct: 124 SVDNAASQTPIGRNLGR-NDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYIES 182
Query: 203 TATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGF 262
ATS MS+++ +WRKENFNIT DDLK GEKR IP PTC F DAFQ YP+++++I + G
Sbjct: 183 KATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGI 242
Query: 263 QKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVL 322
KPTPIQSQAWPI+LQGIDLI VAQTGTGKTL YLMPGFIHL QP + QRN PGMLVL
Sbjct: 243 VKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVL 302
Query: 323 TPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMS 382
TPTRELAL VE EC KYSYKGL+S+C+YGG NR+ QIE++ KGVDIIIATPGRLNDLQM+
Sbjct: 303 TPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMN 362
Query: 383 NFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYL 442
N VNL++ITYLV+DEADKMLDM FEPQI KILLDVRPDRQTVMTSATWP +V +LA SYL
Sbjct: 363 NSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYL 422
Query: 443 KEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADH 502
K+PMIVYVG L+LVAV++VKQNIIVTTE+EK + Q F+++MS DKVI+FVS+K +AD
Sbjct: 423 KDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADD 482
Query: 503 LSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNF 562
LSSD + IS ESLHG+ EQ D+E+A+E+FK+G ++ILI TD+ SRGLD++DVTHVYN+
Sbjct: 483 LSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNY 542
Query: 563 DFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAE 622
DFPRNI+ YVHR+G GR G+TG S+T +T+ D ++A ELI IL+RANQS+PE+LV MAE
Sbjct: 543 DFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAE 602
Query: 623 RFKAHQQKREMERKMERPQGRPKKFH 648
++K +QQKR E + +P R K+F+
Sbjct: 603 QYKLNQQKRHRETRSRKPGQRRKEFY 628
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 343 bits (880), Expect = 3e-94
Identities = 195/449 (43%), Positives = 277/449 (61%), Gaps = 16/449 (3%)
Query: 180 GLKWQKTKWA--DLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIP 237
G K K KW +LP +KNFY+E + + E +++R+ IT P
Sbjct: 38 GEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSK-EITV------RGHNCP 90
Query: 238 NPTCTFDDAFQCYP-EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296
P F +A +P VM+ I + F +PT IQ+Q WP+ L G+D++GVAQTG+GKTL Y
Sbjct: 91 KPVLNFYEAN--FPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSY 148
Query: 297 LMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNR 355
L+P +H+ QP L+ + + P LVL PTRELA QV+ +Y L+S C+YGG +
Sbjct: 149 LLPAIVHINHQPFLE-RGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPK 207
Query: 356 DEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILL 415
QI +L++GV+I IATPGRL D NL+ TYLVLDEAD+MLDMGFEPQI KI+
Sbjct: 208 GPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVD 267
Query: 416 DVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475
+RPDRQT+M SATWP V +LA+ +LK+ + + +G L+L A ++ Q + V + EK
Sbjct: 268 QIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDE 327
Query: 476 HMQTFLQSMSS--TDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENF 533
+ ++ + S +K IVFV K D L+ + +HGD+ Q++R+ L F
Sbjct: 328 KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEF 387
Query: 534 KTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTR 593
K GK ILIATD+ASRGLDV DV V N+D+P + E+Y+HRIGRT R+ +TG + T T
Sbjct: 388 KHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTP 447
Query: 594 NDWRVASELINILERANQSIPEELVSMAE 622
N+ + S+LI++L ANQ+I +L+ + E
Sbjct: 448 NNIKQVSDLISVLREANQAINPKLLQLVE 476
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 342 bits (877), Expect = 6e-94
Identities = 194/446 (43%), Positives = 283/446 (63%), Gaps = 18/446 (4%)
Query: 193 PIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQC--Y 250
P +KNFY E + MS+ E + +R E IT + + P P ++ QC
Sbjct: 330 PFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV------KGKGCPKPIKSW---VQCGIS 380
Query: 251 PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSL 310
+++ ++KK G++KPTPIQ+QA P ++ G DLIG+A+TG+GKT+ +L+P F H++ Q SL
Sbjct: 381 MKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSL 440
Query: 311 KGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVDII 369
+ + P +++TPTRELALQ+ EC K+S GLR VCVYGG EQI ELK+G +II
Sbjct: 441 E-EGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEII 499
Query: 370 IATPGRLNDLQMSN---FVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426
+ TPGR+ D+ +N NL+ +TY+VLDEAD+M DMGFEPQ+M+I+ +VRPDRQTVM
Sbjct: 500 VCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMF 559
Query: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSS 486
SAT+P ++ LA+ L +P+ V VG +V S V+Q +IV EE+K+ + L
Sbjct: 560 SATFPRAMEALARRILSKPIEVQVGGRSVVC-SDVEQQVIVIEEEKKFLKLLELLGHYQE 618
Query: 487 TDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDL 546
+ VI+FV ++ AD L DL+ + SLHG +Q DR+ + +FK G ++L+AT +
Sbjct: 619 SGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSV 678
Query: 547 ASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINIL 606
A+RGLDV + V N+ P + E+YVHR GRTGRAG G + T +T + R A ++I L
Sbjct: 679 AARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKAL 738
Query: 607 ERANQSIPEELVSMAERFKAHQQKRE 632
E + ++P +L + FK QQK E
Sbjct: 739 ELSGTAVPPDLEKLWSDFK-DQQKAE 763
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 335 bits (860), Expect = 6e-92
Identities = 194/455 (42%), Positives = 274/455 (60%), Gaps = 27/455 (5%)
Query: 180 GLKWQKTKW--ADLPPIKKNFYKESTATSAMSKVEADSW-RKENFNITWDDLKDGEKRPI 236
G + +K KW ++LP +KNFY E + ++ E D RK+ + D+
Sbjct: 114 GERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDV-------C 166
Query: 237 PNPTCTFDDA-FQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLC 295
P P F A F Y VM+ + F +PTPIQ Q +P+ L G D++G+AQTG+GKTL
Sbjct: 167 PKPVFAFHHANFPQY--VMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLA 224
Query: 296 YLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVE------GECCKYSYKGLRSVCV 349
YL+P +H+ QP L+ + + P LVL PTRELA QV+ G+C + L+S C+
Sbjct: 225 YLLPAIVHINHQPYLE-RGDGPICLVLAPTRELAQQVQQVADDYGKCSR-----LKSTCI 278
Query: 350 YGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQ 409
YGG + QI +L++GV+I IATPGRL D S NL+ TYLVLDEAD+MLDMGFEPQ
Sbjct: 279 YGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQ 338
Query: 410 IMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTT 469
I KI+ +RPDRQT+M SATWP V +LA+ +L++ + VG L+L A ++ Q + V
Sbjct: 339 IRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCM 398
Query: 470 EEEKWSHMQTFLQSM--SSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527
E EK + ++ + +K I+FV K D L+ + +HGD+ Q +R+
Sbjct: 399 ESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERD 458
Query: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587
L F++GK ILIATD+ASRGLDV DV V N+D+P + E+YVHRIGRT R+ G +
Sbjct: 459 WVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518
Query: 588 ITTLTRNDWRVASELINILERANQSIPEELVSMAE 622
T T + + A ELI +LE ANQ+I +L+ + +
Sbjct: 519 YTFFTPGNLKQARELIKVLEEANQAINPKLMQLVD 553
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 335 bits (860), Expect = 6e-92
Identities = 194/455 (42%), Positives = 274/455 (60%), Gaps = 27/455 (5%)
Query: 180 GLKWQKTKW--ADLPPIKKNFYKESTATSAMSKVEADSW-RKENFNITWDDLKDGEKRPI 236
G + +K KW ++LP +KNFY E + ++ E D RK+ + D+
Sbjct: 114 GERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDV-------C 166
Query: 237 PNPTCTFDDA-FQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLC 295
P P F A F Y VM+ + F +PTPIQ Q +P+ L G D++G+AQTG+GKTL
Sbjct: 167 PKPVFAFHHANFPQY--VMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLA 224
Query: 296 YLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVE------GECCKYSYKGLRSVCV 349
YL+P +H+ QP L+ + + P LVL PTRELA QV+ G+C + L+S C+
Sbjct: 225 YLLPAIVHINHQPYLE-RGDGPICLVLAPTRELAQQVQQVADDYGKCSR-----LKSTCI 278
Query: 350 YGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQ 409
YGG + QI +L++GV+I IATPGRL D S NL+ TYLVLDEAD+MLDMGFEPQ
Sbjct: 279 YGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQ 338
Query: 410 IMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTT 469
I KI+ +RPDRQT+M SATWP V +LA+ +L++ + VG L+L A ++ Q + V
Sbjct: 339 IRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCM 398
Query: 470 EEEKWSHMQTFLQSM--SSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527
E EK + ++ + +K I+FV K D L+ + +HGD+ Q +R+
Sbjct: 399 ESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERD 458
Query: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587
L F++GK ILIATD+ASRGLDV DV V N+D+P + E+YVHRIGRT R+ G +
Sbjct: 459 WVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518
Query: 588 ITTLTRNDWRVASELINILERANQSIPEELVSMAE 622
T T + + A ELI +LE ANQ+I +L+ + +
Sbjct: 519 YTFFTPGNLKQARELIKVLEEANQAINPKLMQLVD 553
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 294 bits (753), Expect = 2e-79
Identities = 169/452 (37%), Positives = 262/452 (57%), Gaps = 20/452 (4%)
Query: 190 DLPPIKKNFYKESTATSAMSKVEA-DSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQ 248
D PP +KNFY E + ++ + D K N ++ G P P + F
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVS------GAAPPRPGSSFAH---FG 259
Query: 249 CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQP 308
++M I+K+ + +PTPIQ Q P+ L G D+IG+A+TG+GKT ++ P IH++ Q
Sbjct: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319
Query: 309 SLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVD 367
L+ + P +++ PTREL Q+ EC ++ LRSV VYGGG+ EQ + L++G +
Sbjct: 320 ELE-PGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378
Query: 368 IIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTS 427
I++ TPGRL D NL+ ++YLV DEAD+M DMGFE Q+ I VRPDRQT++ S
Sbjct: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438
Query: 428 ATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST 487
AT+ + +LA+ L +P+ V G + + I+ + KW+ + L +S+
Sbjct: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS 498
Query: 488 DKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLA 547
V++FV++KA A+ L+++L ++ LHGD +Q +R K + +FK + +L+ATD+A
Sbjct: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
Query: 548 SRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILE 607
+RGLD+ + V N+D R+I+ + HRIGRTGRAG GV+ T LT D A +L+ LE
Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618
Query: 608 RANQSIPEELVSMA--------ERFKAHQQKR 631
ANQ + +EL+ +A RFK + K+
Sbjct: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 294 bits (753), Expect = 2e-79
Identities = 169/452 (37%), Positives = 262/452 (57%), Gaps = 20/452 (4%)
Query: 190 DLPPIKKNFYKESTATSAMSKVEA-DSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQ 248
D PP +KNFY E + ++ + D K N ++ G P P + F
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVS------GAAPPRPGSSFAH---FG 259
Query: 249 CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQP 308
++M I+K+ + +PTPIQ Q P+ L G D+IG+A+TG+GKT ++ P IH++ Q
Sbjct: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319
Query: 309 SLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVD 367
L+ + P +++ PTREL Q+ EC ++ LRSV VYGGG+ EQ + L++G +
Sbjct: 320 ELE-PGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378
Query: 368 IIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTS 427
I++ TPGRL D NL+ ++YLV DEAD+M DMGFE Q+ I VRPDRQT++ S
Sbjct: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438
Query: 428 ATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST 487
AT+ + +LA+ L +P+ V G + + I+ + KW+ + L +S+
Sbjct: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS 498
Query: 488 DKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLA 547
V++FV++KA A+ L+++L ++ LHGD +Q +R K + +FK + +L+ATD+A
Sbjct: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
Query: 548 SRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILE 607
+RGLD+ + V N+D R+I+ + HRIGRTGRAG GV+ T LT D A +L+ LE
Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618
Query: 608 RANQSIPEELVSMA--------ERFKAHQQKR 631
ANQ + +EL+ +A RFK + K+
Sbjct: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 292 bits (748), Expect = 6e-79
Identities = 181/437 (41%), Positives = 260/437 (59%), Gaps = 42/437 (9%)
Query: 216 WR--KENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAW 273
WR +E+++IT K G+ IPNP ++ D+ P ++E I K G+++PTPIQ QA
Sbjct: 370 WRIFREDYSIT---TKGGK---IPNPIRSWKDS-SLPPHILEVIDKCGYKEPTPIQRQAI 422
Query: 274 PIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSL---KGQRNRPGMLVLTPTRELAL 330
PI LQ D+IGVA+TG+GKT +L+P + + P + + P ++L PTRELA
Sbjct: 423 PIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQ 482
Query: 331 QVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKN 389
Q+E E K+ G+R+V V GG +R++Q L+ G +I+IATPGRL D+ + ++ L
Sbjct: 483 QIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSR 542
Query: 390 ITYLVLDEADKMLDMGFEPQIMKILLDV-----RPD---------------------RQT 423
TY+VLDEAD+M+DMGFEP + KIL + +PD RQT
Sbjct: 543 CTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQT 602
Query: 424 VMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQS 483
VM +AT P +V RLA+SYL+ P +VY+G+ V+Q + + +E EK + L+
Sbjct: 603 VMFTATMPPAVERLARSYLRRPAVVYIGSAGKPH-ERVEQKVFLMSESEKRKKLLAILEQ 661
Query: 484 MSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543
+I+FV++K D L+ L + +LHG + Q RE AL N K G IL+A
Sbjct: 662 -GFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVA 720
Query: 544 TDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603
TD+A RG+D+ DV+ V N+D +NIE+Y+HRIGRTGRAG++GV+IT LT+ D V EL
Sbjct: 721 TDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELK 780
Query: 604 N-ILERANQSIPEELVS 619
ILE S P EL +
Sbjct: 781 QAILESPVSSCPPELAN 797
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 274 bits (700), Expect = 2e-73
Identities = 156/386 (40%), Positives = 229/386 (59%), Gaps = 18/386 (4%)
Query: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGF----------- 301
+M NI+ + +PTP+Q A PI+ + DL+ AQTG+GKT +L+P
Sbjct: 191 IMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEA 250
Query: 302 IHLVLQPSLKGQRNR-PGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGGGNRDEQI 359
+ + + G+R + P LVL PTRELA+Q+ E K+SY+ +R VYGG + +QI
Sbjct: 251 LRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 310
Query: 360 EELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL-LDVR 418
+L++G +++ATPGRL D+ + L YLVLDEAD+MLDMGFEPQI +I+ D
Sbjct: 311 RDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTM 370
Query: 419 PD---RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475
P R T+M SAT+P + LA+ +L E + + VG + + ++ Q ++ E +K S
Sbjct: 371 PPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEESDKRS 429
Query: 476 HMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKT 535
+ L + +VFV K AD L L + S+HGDR QRDRE+AL F++
Sbjct: 430 FLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRS 489
Query: 536 GKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595
GK IL+AT +A+RGLD+ +V HV NFD P +IEEYVHRIGRTGR G G++ + +
Sbjct: 490 GKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERN 549
Query: 596 WRVASELINILERANQSIPEELVSMA 621
+ +L+++L A Q +P L +MA
Sbjct: 550 INITKDLLDLLVEAKQEVPSWLENMA 575
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 273 bits (698), Expect = 4e-73
Identities = 160/395 (40%), Positives = 238/395 (60%), Gaps = 13/395 (3%)
Query: 237 PNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296
P TF++A C + NI KAG+ K TP+Q + PI+L G DL+ AQTG+GKT +
Sbjct: 284 PPAILTFEEANLCQT-LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAF 342
Query: 297 LMPGFIHLV---LQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGG 352
L+P H++ + S + P +++ PTREL Q+ E K+S+ +R+V +YGG
Sbjct: 343 LLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGG 402
Query: 353 GNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMK 412
I ++ +G +I+ ATPGRL D+ + LK I YLVLDEAD+MLDMGF P++ K
Sbjct: 403 TQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKK 462
Query: 413 IL----LDVRPDRQTVMTSATWPHSVHRLAQSYLKEP-MIVYVGTLDLVAVSSVKQNIIV 467
++ + + RQT+M SAT+P + RLA +LK + V VG + A V+Q ++
Sbjct: 463 LISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQ 521
Query: 468 TTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527
+ K + L+++ ++ +VFV K AD +++ L IS S+HGDREQR+RE
Sbjct: 522 VGQFSKREKLVEILRNIGD-ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRERE 580
Query: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587
+AL +F+ GK +L+AT +A+RGLD+ +V HV NFD P I+EYVHRIGRTGR G TG +
Sbjct: 581 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 640
Query: 588 ITTL-TRNDWRVASELINILERANQSIPEELVSMA 621
I+ +D +A L+ +L A Q +P L +A
Sbjct: 641 ISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 273 bits (698), Expect = 4e-73
Identities = 160/395 (40%), Positives = 238/395 (60%), Gaps = 13/395 (3%)
Query: 237 PNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296
P TF++A C + NI KAG+ K TP+Q + PI+L G DL+ AQTG+GKT +
Sbjct: 284 PPAILTFEEANLCQT-LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAF 342
Query: 297 LMPGFIHLV---LQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGG 352
L+P H++ + S + P +++ PTREL Q+ E K+S+ +R+V +YGG
Sbjct: 343 LLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGG 402
Query: 353 GNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMK 412
I ++ +G +I+ ATPGRL D+ + LK I YLVLDEAD+MLDMGF P++ K
Sbjct: 403 TQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKK 462
Query: 413 IL----LDVRPDRQTVMTSATWPHSVHRLAQSYLKEP-MIVYVGTLDLVAVSSVKQNIIV 467
++ + + RQT+M SAT+P + RLA +LK + V VG + A V+Q ++
Sbjct: 463 LISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQ 521
Query: 468 TTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527
+ K + L+++ ++ +VFV K AD +++ L IS S+HGDREQR+RE
Sbjct: 522 VGQFSKREKLVEILRNIGD-ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRERE 580
Query: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587
+AL +F+ GK +L+AT +A+RGLD+ +V HV NFD P I+EYVHRIGRTGR G TG +
Sbjct: 581 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 640
Query: 588 ITTL-TRNDWRVASELINILERANQSIPEELVSMA 621
I+ +D +A L+ +L A Q +P L +A
Sbjct: 641 ISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 273 bits (698), Expect = 4e-73
Identities = 160/395 (40%), Positives = 238/395 (60%), Gaps = 13/395 (3%)
Query: 237 PNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296
P TF++A C + NI KAG+ K TP+Q + PI+L G DL+ AQTG+GKT +
Sbjct: 250 PPAILTFEEANLCQT-LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAF 308
Query: 297 LMPGFIHLV---LQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGG 352
L+P H++ + S + P +++ PTREL Q+ E K+S+ +R+V +YGG
Sbjct: 309 LLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGG 368
Query: 353 GNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMK 412
I ++ +G +I+ ATPGRL D+ + LK I YLVLDEAD+MLDMGF P++ K
Sbjct: 369 TQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKK 428
Query: 413 IL----LDVRPDRQTVMTSATWPHSVHRLAQSYLKEP-MIVYVGTLDLVAVSSVKQNIIV 467
++ + + RQT+M SAT+P + RLA +LK + V VG + A V+Q ++
Sbjct: 429 LISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQ 487
Query: 468 TTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527
+ K + L+++ ++ +VFV K AD +++ L IS S+HGDREQR+RE
Sbjct: 488 VGQFSKREKLVEILRNIGD-ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRERE 546
Query: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587
+AL +F+ GK +L+AT +A+RGLD+ +V HV NFD P I+EYVHRIGRTGR G TG +
Sbjct: 547 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 606
Query: 588 ITTL-TRNDWRVASELINILERANQSIPEELVSMA 621
I+ +D +A L+ +L A Q +P L +A
Sbjct: 607 ISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 641
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 272 bits (696), Expect = 6e-73
Identities = 157/386 (40%), Positives = 229/386 (59%), Gaps = 18/386 (4%)
Query: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHL-------- 304
+M NI+ + +PTP+Q A PI+ DL+ AQTG+GKT +L+P +
Sbjct: 189 IMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEA 248
Query: 305 ---VLQPSLKGQRNR-PGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGGGNRDEQI 359
V + G+R + P LVL PTRELA+Q+ E K+SY+ +R VYGG + +QI
Sbjct: 249 LKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 308
Query: 360 EELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL-LDVR 418
+L++G +++ATPGRL D+ + L YLVLDEAD+MLDMGFEPQI +I+ D
Sbjct: 309 RDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTM 368
Query: 419 PD---RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475
P R T+M SAT+P + LA+ +L E + + VG + + ++ Q ++ + +K S
Sbjct: 369 PPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEDLDKRS 427
Query: 476 HMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKT 535
+ L + S +VFV K AD L L + S+HGDR QRDRE+AL F++
Sbjct: 428 FLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRS 487
Query: 536 GKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595
GK IL+AT +A+RGLD+ +V HV NFD P +IEEYVHRIGRTGR G G++ + +
Sbjct: 488 GKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKN 547
Query: 596 WRVASELINILERANQSIPEELVSMA 621
+ +L+++L A Q +P L +MA
Sbjct: 548 MNITKDLLDLLVEAKQEVPSWLENMA 573
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 272 bits (696), Expect = 6e-73
Identities = 157/386 (40%), Positives = 229/386 (59%), Gaps = 18/386 (4%)
Query: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHL-------- 304
+M NI+ + +PTP+Q A PI+ DL+ AQTG+GKT +L+P +
Sbjct: 189 IMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEA 248
Query: 305 ---VLQPSLKGQRNR-PGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGGGNRDEQI 359
V + G+R + P LVL PTRELA+Q+ E K+SY+ +R VYGG + +QI
Sbjct: 249 LKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 308
Query: 360 EELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL-LDVR 418
+L++G +++ATPGRL D+ + L YLVLDEAD+MLDMGFEPQI +I+ D
Sbjct: 309 RDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTM 368
Query: 419 PD---RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475
P R T+M SAT+P + LA+ +L E + + VG + + ++ Q ++ + +K S
Sbjct: 369 PPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEDLDKRS 427
Query: 476 HMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKT 535
+ L + S +VFV K AD L L + S+HGDR QRDRE+AL F++
Sbjct: 428 FLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRS 487
Query: 536 GKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595
GK IL+AT +A+RGLD+ +V HV NFD P +IEEYVHRIGRTGR G G++ + +
Sbjct: 488 GKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKN 547
Query: 596 WRVASELINILERANQSIPEELVSMA 621
+ +L+++L A Q +P L +MA
Sbjct: 548 MNITKDLLDLLVEAKQEVPSWLENMA 573
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 247 bits (630), Expect = 3e-65
Identities = 148/392 (37%), Positives = 218/392 (55%), Gaps = 14/392 (3%)
Query: 236 IPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLC 295
IP P +F + + ++ +KK G PTPIQ Q P +L G D+IG+A TG+GKTL
Sbjct: 176 IPPPIKSFKE-MKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLV 234
Query: 296 YLMPGFIHLVLQPSLK--GQRNRPGMLVLTPTRELALQVEGECCKY-------SYKGLRS 346
+ +P + + Q +R P L++ P+RELA Q G Y S LR
Sbjct: 235 FTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRC 294
Query: 347 VCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGF 406
GG + EQ+E ++ GV +++ATPGRL DL V+L YL LDEAD+M+DMGF
Sbjct: 295 ALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGF 354
Query: 407 EPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNII 466
E I I + RQT++ SAT P + A+S L +P+ + VG ++ + Q +
Sbjct: 355 EGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVI-QEVE 413
Query: 467 VTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDR 526
EE K ++ LQ + V++F +KA D + L+L + ++HG ++Q +R
Sbjct: 414 YVKEEAKMVYLLECLQK--TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEER 471
Query: 527 EKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGV 586
KA+E F+ GK +L+ATD+AS+GLD + HV N+D P IE YVHRIGRTGR+G TG+
Sbjct: 472 TKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGI 531
Query: 587 SITTLTRN-DWRVASELINILERANQSIPEEL 617
+ T + + D V +L +L A Q +P L
Sbjct: 532 ATTFINKACDESVLMDLKALLLEAKQKVPPVL 563
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 220 bits (561), Expect = 3e-57
Identities = 141/398 (35%), Positives = 225/398 (56%), Gaps = 19/398 (4%)
Query: 251 PEVME-NIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPS 309
PEV+ N+KK+G++ PTPIQ Q P+ L G D++ A TG+GKT +L+P + + +
Sbjct: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESK 270
Query: 310 LKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGL---RSVCVYGGGNRDEQIEELKKGV 366
P L+LTPTRELA+Q+E + K GL ++V + GG Q+ L++ V
Sbjct: 271 T------PSALILTPTRELAIQIERQA-KELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323
Query: 367 DIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426
+IIATPGRL D+ + V L + +V+DEAD ML MGF+ Q++ IL ++ D QT++
Sbjct: 324 KVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILV 383
Query: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMS- 485
SAT P S+ +LA L P+ + G +L ++V+Q I+ + K + L
Sbjct: 384 SATIPTSIEQLASQLLHNPVRIITGEKNL-PCANVRQIILWVEDPAKKKKLFEILNDKKL 442
Query: 486 STDKVIVFVSRKAVADHLSSDL--ILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543
V+VFV K AD LS + I G S+ S+H ++ Q +R+ L+ G ++++
Sbjct: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSI-SIHSEKSQIERKNILKGLLEGDYEVVVS 501
Query: 544 TDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603
T + RGLD+ V V NFD P +++EYVH+IGR GR G+ G +IT + N R+ ++
Sbjct: 502 TGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIA 561
Query: 604 NILERANQSIPEELVSMAERFKAHQQKREMERKMERPQ 641
++ +P +L++ H QKR+ ++K ++ Q
Sbjct: 562 KRVKPTGSILPPQLLNSP---YLHDQKRKEQQKDKQTQ 596
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 213 bits (541), Expect = 6e-55
Identities = 154/477 (32%), Positives = 252/477 (52%), Gaps = 27/477 (5%)
Query: 177 REEG--LKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLK-DGEK 233
+EEG ++W + A + K +ES TS + ++ RKE N + K +
Sbjct: 100 QEEGATIQWMSSVEAKIED--KKVQRESKLTSG----KLENLRKEKINFLRNKHKIHVQG 153
Query: 234 RPIPNPTCTF---DDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGT 290
+P+P TF D ++ +++NI AGFQ PTPIQ QA P++L G +L+ A TG+
Sbjct: 154 TDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGS 213
Query: 291 GKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSY-KGLRSVCV 349
GKTL + +P + L QP+ KG R L+++PTRELA Q+ E K S G R +
Sbjct: 214 GKTLAFSIPILMQLK-QPANKGFR----ALIISPTRELASQIHRELIKISEGTGFRIHMI 268
Query: 350 YGGGNRDEQI-EELKKGVDIIIATPGRLNDL--QMSNFVNLKNITYLVLDEADKMLD--- 403
+ ++ + K DI++ TP RL L Q ++L ++ +LV+DE+DK+ +
Sbjct: 269 HKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGK 328
Query: 404 MGFEPQIMKILLDVRPDR-QTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVK 462
GF Q+ I L + + M SAT+ + V + + L + V +G + AV +V+
Sbjct: 329 TGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVE 387
Query: 463 QNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDRE 522
Q ++ E L V+VFV A L +LI I+V+ +H +R
Sbjct: 388 QELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERT 447
Query: 523 QRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAG 582
Q+ R+ + +F+ GK+ +LI T L +RG+D V V N+DFP + EY+HRIGRTGRAG
Sbjct: 448 QQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAG 507
Query: 583 RTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKREMERKMER 639
G +IT T +D + + N++++A +PE + ++ + Q+K+ +++ +ER
Sbjct: 508 NKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGF-QKLLSKQKKKMIKKPLER 563
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 211 bits (537), Expect = 2e-54
Identities = 149/456 (32%), Positives = 242/456 (53%), Gaps = 23/456 (5%)
Query: 196 KNFYKESTATSAMSKVEADSWRKENFNITWDDLK-DGEKRPIPNPTCTF---DDAFQCYP 251
K +ES TS + ++ RKE N + K + +P+P TF D ++
Sbjct: 11 KKVQRESKLTSG----KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINS 66
Query: 252 EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLK 311
+++NI AGFQ PTPIQ QA P++L G +L+ A TG+GKTL + +P + L QP+ K
Sbjct: 67 RLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QPANK 125
Query: 312 GQRNRPGMLVLTPTRELALQVEGECCKYSY-KGLRSVCVYGGGNRDEQI-EELKKGVDII 369
G R L+++PTRELA Q+ E K S G R ++ ++ + K DI+
Sbjct: 126 GFR----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDIL 181
Query: 370 IATPGRLNDL--QMSNFVNLKNITYLVLDEADKMLD---MGFEPQIMKILLDVRPDR-QT 423
+ TP RL L Q ++L ++ +LV+DE+DK+ + GF Q+ I L + +
Sbjct: 182 VTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRR 241
Query: 424 VMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQS 483
M SAT+ + V + + L + V +G + AV +V+Q ++ E L
Sbjct: 242 AMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVEQELLFVGSETGKLLAMRELVK 300
Query: 484 MSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543
V+VFV A L +LI I+V+ +H +R Q+ R+ + +F+ GK+ +LI
Sbjct: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
Query: 544 TDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603
T L +RG+D V V N+DFP + EY+HRIGRTGRAG G +IT T +D + +
Sbjct: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
Query: 604 NILERANQSIPEELVSMAERFKAHQQKREMERKMER 639
N++++A +PE + ++ + Q+K+ +++ +ER
Sbjct: 421 NVIQQAGCPVPEYIKGF-QKLLSKQKKKMIKKPLER 455
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 208 bits (530), Expect = 1e-53
Identities = 137/403 (33%), Positives = 219/403 (54%), Gaps = 15/403 (3%)
Query: 202 STATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAG 261
+TAT A S KE ++T + + E+ + T TFD +++ I G
Sbjct: 3 TTATMATSGSARKRLLKEE-DMTKVEFETSEEVDV---TPTFD-TMGLREDLLRGIYAYG 57
Query: 262 FQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLV 321
F+KP+ IQ +A +++G D+I +Q+GTGKT + + VLQ L Q L+
Sbjct: 58 FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSIS-----VLQ-CLDIQVRETQALI 111
Query: 322 LTPTRELALQVE-GECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQ 380
L PTRELA+Q++ G Y ++ GG N E I +L G ++ TPGR+ D+
Sbjct: 112 LAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMI 171
Query: 381 MSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQS 440
+ + I LVLDEAD+ML+ GF+ QI + + P Q V+ SAT PH + +
Sbjct: 172 RRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNK 231
Query: 441 YLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEE-KWSHMQTFLQSMSSTDKVIVFVSRKAV 499
++ +P+ + V D + + +KQ + EE K+ + +++ T VI F + K
Sbjct: 232 FMTDPIRILVKR-DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVI-FCNTKRK 289
Query: 500 ADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHV 559
D L+ + N +V S+HGD Q++RE ++ F++G R+LI+TD+ +RGLDV V+ +
Sbjct: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349
Query: 560 YNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASEL 602
N+D P N E Y+HRIGR+GR GR GV+I + +D R+ ++
Sbjct: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 203 bits (517), Expect = 4e-52
Identities = 121/350 (34%), Positives = 202/350 (57%), Gaps = 12/350 (3%)
Query: 250 YPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPS 309
YP V + I K G++ PTPIQ + P++L G D++ +A+TG+GKT C+L+P F L +
Sbjct: 105 YP-VFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSA 163
Query: 310 LKGQRNRPGMLVLTPTRELALQV---EGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGV 366
G R L+L+PTRELALQ E K++ GL++ + GG ++Q L +
Sbjct: 164 QTGAR----ALILSPTRELALQTLKFTKELGKFT--GLKTALILGGDRMEDQFAALHENP 217
Query: 367 DIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426
DIIIATPGRL + + + L+++ Y+V DEAD++ +MGF Q+ +I+ + QTV+
Sbjct: 218 DIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLF 277
Query: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQS-MS 485
SAT P + A++ L EP+++ + +D +K + + E+ K + + L + +
Sbjct: 278 SATLPKLLVEFARAGLTEPVLIRL-DVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVR 336
Query: 486 STDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATD 545
D+ +VFV+ K A++L+ L +S ++ + R+ L F GK LI TD
Sbjct: 337 PQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTD 396
Query: 546 LASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595
LA+RGLD+ + +V N+ FP + ++HR+GR RAGR+G + + + ++
Sbjct: 397 LAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDE 446
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 203 bits (517), Expect = 4e-52
Identities = 121/350 (34%), Positives = 202/350 (57%), Gaps = 12/350 (3%)
Query: 250 YPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPS 309
YP V + I K G++ PTPIQ + P++L G D++ +A+TG+GKT C+L+P F L +
Sbjct: 105 YP-VFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSA 163
Query: 310 LKGQRNRPGMLVLTPTRELALQV---EGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGV 366
G R L+L+PTRELALQ E K++ GL++ + GG ++Q L +
Sbjct: 164 QTGAR----ALILSPTRELALQTLKFTKELGKFT--GLKTALILGGDRMEDQFAALHENP 217
Query: 367 DIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426
DIIIATPGRL + + + L+++ Y+V DEAD++ +MGF Q+ +I+ + QTV+
Sbjct: 218 DIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLF 277
Query: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQS-MS 485
SAT P + A++ L EP+++ + +D +K + + E+ K + + L + +
Sbjct: 278 SATLPKLLVEFARAGLTEPVLIRL-DVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVR 336
Query: 486 STDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATD 545
D+ +VFV+ K A++L+ L +S ++ + R+ L F GK LI TD
Sbjct: 337 PQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTD 396
Query: 546 LASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595
LA+RGLD+ + +V N+ FP + ++HR+GR RAGR+G + + + ++
Sbjct: 397 LAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDE 446
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 202 bits (514), Expect = 8e-52
Identities = 144/399 (36%), Positives = 219/399 (54%), Gaps = 20/399 (5%)
Query: 255 ENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQR 314
E + G+ KPT IQ +A P+ LQG D+IG+A+TG+GKT + +P L+ P
Sbjct: 37 EACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQ----- 91
Query: 315 NRPGMLVLTPTRELALQVEGEC-CKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATP 373
R LVLTPTRELA Q+ + S G++S + GG + Q L K IIIATP
Sbjct: 92 -RLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATP 150
Query: 374 GRLND-LQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPH 432
GRL D L+ + NL+ + YLV+DEAD++L+M FE ++ KIL + DR+T + SAT
Sbjct: 151 GRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTK 210
Query: 433 SVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIV 492
V +L ++ LK P+ V + V ++Q I + K +++ L ++ + ++
Sbjct: 211 KVQKLQRAALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG-NSFMI 268
Query: 493 FVSRKAVADHLSSDLILGNISVES--LHGDREQRDREKALENFKTGKVRILIATDLASRG 550
F S + + L+L N+ + LHG Q R +L FK IL+ATD+ASRG
Sbjct: 269 FCS--TCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRG 326
Query: 551 LDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERAN 610
LD+ V V NFD P + ++Y+HR+GRT RAGR+G +IT +T+ D + + +++ +
Sbjct: 327 LDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKL 386
Query: 611 QSIP---EELVSMAERFKAHQQKREMERKMERPQGRPKK 646
P +E++ + ER Q+ ME R G KK
Sbjct: 387 PGFPTQDDEVMMLTERVAEAQRFARMEL---REHGEKKK 422
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 199 bits (507), Expect = 5e-51
Identities = 125/375 (33%), Positives = 203/375 (54%), Gaps = 10/375 (2%)
Query: 242 TFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGF 301
+FDD ++ I GF+KP+ IQ +A ++G D+I AQ+GTGKT + +
Sbjct: 33 SFDD-MNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAIS-- 89
Query: 302 IHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIE 360
I ++ LK + LVL PTRELA Q++ Y G GG N +++
Sbjct: 90 ILQQIELDLKATQ----ALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQ 145
Query: 361 ELK-KGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRP 419
+L+ + II+ TPGR+ D+ +++ K I VLDEAD+ML GF+ QI I +
Sbjct: 146 KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS 205
Query: 420 DRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQT 479
+ Q V+ SAT P V + + ++++P+ + V +L + I V EE K +
Sbjct: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
Query: 480 FLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVR 539
++++ T VI F++ + D L+ + + +V ++HGD +Q++R+ + F++G R
Sbjct: 266 LYETLTITQAVI-FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324
Query: 540 ILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVA 599
+LI TDL +RG+DV V+ V N+D P N E Y+HRIGR GR GR GV+I +T D R
Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTL 384
Query: 600 SELINILERANQSIP 614
++ + + +P
Sbjct: 385 RDIETFYNTSIEEMP 399
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 199 bits (506), Expect = 7e-51
Identities = 126/380 (33%), Positives = 204/380 (53%), Gaps = 10/380 (2%)
Query: 243 FDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFI 302
FDD ++ I GF+KP+ IQ +A ++G D+I AQ+GTGKT + +
Sbjct: 35 FDD-MNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAIS--- 90
Query: 303 HLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIEE 361
+LQ L+ + LVL PTRELA Q++ Y G GG N ++++
Sbjct: 91 --ILQ-QLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQK 147
Query: 362 LK-KGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPD 420
L+ + I++ TPGR+ D+ +++ K I VLDEAD+ML GF+ QI +I +
Sbjct: 148 LQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTS 207
Query: 421 RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTF 480
Q V+ SAT P V + + ++++P+ + V +L + I V EE K +
Sbjct: 208 IQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDL 267
Query: 481 LQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRI 540
++++ T VI +R+ V D L+ + + +V +LHGD +Q++R+ + F++G R+
Sbjct: 268 YETLTITQAVIFLNTRRKV-DWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
Query: 541 LIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVAS 600
LI TDL +RG+DV V+ V N+D P N E Y+HRIGR GR GR GV+I +T D R+
Sbjct: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
Query: 601 ELINILERANQSIPEELVSM 620
++ + +P + +
Sbjct: 387 DIETFYNTTVEEMPMNVADL 406
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 198 bits (503), Expect = 1e-50
Identities = 132/362 (36%), Positives = 195/362 (53%), Gaps = 25/362 (6%)
Query: 244 DDAFQCYP---EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPG 300
+ AF +P E ++ +K G PIQ++ + V G DLI A+TGTGKT + +P
Sbjct: 185 EGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPL 244
Query: 301 F--IHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQ 358
+H LQ +G+ P +LVL PTRELA QV + + K L C YGG Q
Sbjct: 245 IEKLHGELQDRKRGRA--PQVLVLAPTRELANQVSKDFSDITKK-LSVACFYGGTPYGGQ 301
Query: 359 IEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILL--- 415
E ++ G+DI++ TPGR+ D + ++L + ++VLDE D+MLDMGF Q+ +IL
Sbjct: 302 FERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAY 361
Query: 416 --DVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEK 473
D + QT++ SAT PH V +A+ Y+K +DL+ + K I V K
Sbjct: 362 KKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY----EQVDLIGKKTQKTAITVEHLAIK 417
Query: 474 --WSHMQTFLQSM-----SSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDR 526
W+ + + + I+F K A LS + + +SLHGD Q+ R
Sbjct: 418 CHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQR 476
Query: 527 EKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGV 586
E L+ F+ G +L+AT++A+RGLD+ +V V P+++E Y+HR GRTGRAGRTGV
Sbjct: 477 EITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGV 536
Query: 587 SI 588
I
Sbjct: 537 CI 538
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 196 bits (499), Expect = 4e-50
Identities = 129/354 (36%), Positives = 192/354 (54%), Gaps = 6/354 (1%)
Query: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKG 312
+++ I GF++PTPIQ P+ L G D+ A TGTGKT + +P L+ +P
Sbjct: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPR--- 285
Query: 313 QRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIEELKKGVDIIIA 371
Q +LVL PTREL +QV + + + + + GG + Q L+ DI+IA
Sbjct: 286 QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIA 345
Query: 372 TPGRLND-LQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATW 430
TPGRL D L +L +I L+LDEAD+MLD FE Q+ +I+ RQT++ SAT
Sbjct: 346 TPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATM 405
Query: 431 PHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEE-KWSHMQTFLQSMSSTDK 489
V LA LK P+ ++V + VA ++ I + E + L + + TD
Sbjct: 406 TDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDH 465
Query: 490 VIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASR 549
V++F K A + L L + V LHG+ Q R +AL FK ++ IL+ATD+A+R
Sbjct: 466 VMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAAR 525
Query: 550 GLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603
GLD+ V V NF P I+ YVHR+GRT RAGR G S++ + ++ ++ E++
Sbjct: 526 GLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIV 579
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 196 bits (497), Expect = 7e-50
Identities = 141/429 (32%), Positives = 227/429 (52%), Gaps = 30/429 (6%)
Query: 173 WDQIREEGLKWQKTKWADLPPIKKNFY-KESTATSAMSKVEADSWRKENFNITWDDLKDG 231
++++ +E K K++ DLP + Y K+S S++ S K + N + L
Sbjct: 78 FNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDT----STHKSSDNKLEETLTRE 133
Query: 232 EKRPIPNPTCTFDDAFQCYP---EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQT 288
+K + AF +P E ++ +K G PIQ + + V +G DLI A+T
Sbjct: 134 QK----------EGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQART 183
Query: 289 GTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVC 348
GTGKT + +P L + P +LVL PTRELA QV + + K L C
Sbjct: 184 GTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRK-LSVAC 242
Query: 349 VYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEP 408
YGG + QI ++ G+DI++ TPGR+ D S ++L + ++VLDE D+MLD+GF
Sbjct: 243 FYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAE 302
Query: 409 QIMKIL-----LDVRPDRQTVMTSATWPHSVHRLAQSYLKE--PMIVYVGTLDLVAVSSV 461
Q+ I+ D + QT++ SAT P V+++A+ Y+K + VG + A ++V
Sbjct: 303 QVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTV 362
Query: 462 KQNIIVTTEEEKWSHMQTFLQSMSSTD-KVIVFV-SRKAVADHLSSDLILGNISVESLHG 519
+ I ++ + + LQ S ++ + I+F ++K V + + I N + LHG
Sbjct: 363 EHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQN--AQCLHG 420
Query: 520 DREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTG 579
D Q RE L+ F+ G ++L+AT++A+RGLD+ +V V P+++E Y+HR GRTG
Sbjct: 421 DIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTG 480
Query: 580 RAGRTGVSI 588
RAGRTG+ I
Sbjct: 481 RAGRTGICI 489
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 193 bits (491), Expect = 4e-49
Identities = 122/361 (33%), Positives = 193/361 (53%), Gaps = 14/361 (3%)
Query: 240 TCTFDDAFQCY---PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296
T T + F+ Y E++ I + G++KP+PIQ ++ PI L G D++ A+ GTGK+ Y
Sbjct: 91 TSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAY 150
Query: 297 LMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK--GLRSVCVYGGGN 354
L+P L L +++ +V+ PTRELALQV C + S G + + GG N
Sbjct: 151 LIP------LLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTN 204
Query: 355 RDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL 414
+ I L V ++IATPGR+ DL + ++ +VLDEADK+L F + I+
Sbjct: 205 LRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDII 264
Query: 415 LDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKW 474
L + +RQ ++ SAT+P SV + S+L++P + ++ + + V Q TE +K
Sbjct: 265 LTLPKNRQILLYSATFPLSVQKFMNSHLQKPY--EINLMEELTLKGVTQYYAYVTERQK- 321
Query: 475 SHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFK 534
H L S ++ I+F + + L+ + S +H Q R + +F+
Sbjct: 322 VHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFR 381
Query: 535 TGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRN 594
G R L+ TDL +RG+D+ V V NFDFP+ E Y+HRIGR+GR G G++I +T +
Sbjct: 382 NGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYD 441
Query: 595 D 595
D
Sbjct: 442 D 442
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 183 bits (465), Expect = 4e-46
Identities = 134/418 (32%), Positives = 219/418 (52%), Gaps = 21/418 (5%)
Query: 179 EGLKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPN 238
E K +K K + + + K T S+ E+ KE N D ++ +P+
Sbjct: 106 ESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPS 165
Query: 239 PTCTFDDAFQ----------CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQT 288
AF+ ++ IK+ GF T IQ ++ +L+G DL+ A+T
Sbjct: 166 LPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKT 225
Query: 289 GTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSV- 347
G+GKTL +L+P + L+++ RN G+L+L+PTRELA+Q G + + +
Sbjct: 226 GSGKTLAFLIPA-VELIVKLRFM-PRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYG 283
Query: 348 CVYGGGNRDEQIEELKKGVDIIIATPGRLND-LQMSNFVNLKNITYLVLDEADKMLDMGF 406
+ GG NR + ++L G++II+ATPGRL D +Q + KN+ LV+DEAD++LD+GF
Sbjct: 284 LIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGF 343
Query: 407 EPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQ-SYLKEPMIVYVGTLDLVA---VSSVK 462
E ++ +I+ + RQT++ SAT V LA+ S KEP+ YVG D A V ++
Sbjct: 344 EEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPL--YVGVDDDKANATVDGLE 401
Query: 463 QNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDRE 522
Q +V E+++ + TFL+ ++ F S +V H L ++ V ++HG ++
Sbjct: 402 QGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYEL-LNYIDLPVLAIHGKQK 460
Query: 523 QRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGR 580
Q R F L+ TD+A+RGLD+ +V + +D P + +EY+HR+GRT R
Sbjct: 461 QNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,891,304
Number of Sequences: 37866
Number of extensions: 1123703
Number of successful extensions: 3638
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 3264
Number of HSP's gapped (non-prelim): 226
length of query: 648
length of database: 18,247,518
effective HSP length: 109
effective length of query: 539
effective length of database: 14,120,124
effective search space: 7610746836
effective search space used: 7610746836
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.