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Search of human proteins with 222144249
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo
sapiens]
(4753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 9565 0.0
gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens] 1219 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 298 7e-80
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 261 9e-69
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 258 1e-67
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 225 7e-58
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 218 9e-56
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 214 2e-54
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 204 2e-51
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 197 2e-49
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 187 3e-46
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 184 2e-45
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 179 6e-44
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 176 6e-43
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 171 1e-41
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 162 7e-39
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 162 7e-39
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 158 1e-37
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 158 1e-37
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 87 4e-16
gi|17975763 myelin transcription factor 1 [Homo sapiens] 56 1e-06
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 52 1e-05
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 51 2e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 51 2e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 51 3e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 4e-05
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 49 9e-05
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 49 2e-04
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 49 2e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 2e-04
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 9565 bits (24820), Expect = 0.0
Identities = 4753/4753 (100%), Positives = 4753/4753 (100%)
Query: 1 MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60
MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL
Sbjct: 1 MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60
Query: 61 LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120
LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT
Sbjct: 61 LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120
Query: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE
Sbjct: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
Query: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240
LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV
Sbjct: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240
Query: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300
EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV
Sbjct: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300
Query: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360
APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF
Sbjct: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360
Query: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV
Sbjct: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
Query: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480
SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV
Sbjct: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480
Query: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540
QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI
Sbjct: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540
Query: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSA 600
TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSA
Sbjct: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSA 600
Query: 601 DLKTSSDSLYSEEEDEEEDSKDEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL 660
DLKTSSDSLYSEEEDEEEDSKDEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
Sbjct: 601 DLKTSSDSLYSEEEDEEEDSKDEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL 660
Query: 661 EVRGCRLRGQYFPHNYKQLEEDLDNNPKIQQALNIQQVLLEGVLCKVQEFCREHHWITGI 720
EVRGCRLRGQYFPHNYKQLEEDLDNNPKIQQALNIQQVLLEGVLCKVQEFCREHHWITGI
Sbjct: 661 EVRGCRLRGQYFPHNYKQLEEDLDNNPKIQQALNIQQVLLEGVLCKVQEFCREHHWITGI 720
Query: 721 YEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGGLLLLSCHDVQA 780
YEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGGLLLLSCHDVQA
Sbjct: 721 YEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGGLLLLSCHDVQA 780
Query: 781 EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN 840
EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN
Sbjct: 781 EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN 840
Query: 841 EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLH 900
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLH
Sbjct: 841 EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLH 900
Query: 901 CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLAKALSGPF 960
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLAKALSGPF
Sbjct: 901 CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLAKALSGPF 960
Query: 961 MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQR 1020
MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQR
Sbjct: 961 MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQR 1020
Query: 1021 IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL 1080
IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL
Sbjct: 1021 IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL 1080
Query: 1081 GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ 1140
GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ
Sbjct: 1081 GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ 1140
Query: 1141 VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD 1200
VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD
Sbjct: 1141 VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD 1200
Query: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT
Sbjct: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
Query: 1261 FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP 1320
FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP
Sbjct: 1261 FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP 1320
Query: 1321 YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA 1380
YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA
Sbjct: 1321 YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA 1380
Query: 1381 QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL 1440
QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL
Sbjct: 1381 QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL 1440
Query: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500
HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI
Sbjct: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500
Query: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQ 1560
DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQ
Sbjct: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQ 1560
Query: 1561 SLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPL 1620
SLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPL
Sbjct: 1561 SLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPL 1620
Query: 1621 QSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEV 1680
QSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEV
Sbjct: 1621 QSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEV 1680
Query: 1681 ACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEK 1740
ACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEK
Sbjct: 1681 ACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEK 1740
Query: 1741 VHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLG 1800
VHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLG
Sbjct: 1741 VHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLG 1800
Query: 1801 YGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFS 1860
YGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFS
Sbjct: 1801 YGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFS 1860
Query: 1861 LERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSIL 1920
LERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSIL
Sbjct: 1861 LERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSIL 1920
Query: 1921 NGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQ 1980
NGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQ
Sbjct: 1921 NGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQ 1980
Query: 1981 ALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQE 2040
ALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQE
Sbjct: 1981 ALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQE 2040
Query: 2041 FLGWLEGSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITC 2100
FLGWLEGSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITC
Sbjct: 2041 FLGWLEGSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITC 2100
Query: 2101 LLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSAL 2160
LLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSAL
Sbjct: 2101 LLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSAL 2160
Query: 2161 MASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSM 2220
MASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSM
Sbjct: 2161 MASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSM 2220
Query: 2221 ARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREH 2280
ARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREH
Sbjct: 2221 ARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREH 2280
Query: 2281 LLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDG 2340
LLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDG
Sbjct: 2281 LLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDG 2340
Query: 2341 TLVPFTGQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV 2400
TLVPFTGQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV
Sbjct: 2341 TLVPFTGQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV 2400
Query: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA 2460
LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA
Sbjct: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA 2460
Query: 2461 TSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFR 2520
TSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFR
Sbjct: 2461 TSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFR 2520
Query: 2521 LFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNCFMP 2580
LFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNCFMP
Sbjct: 2521 LFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNCFMP 2580
Query: 2581 SPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMAT 2640
SPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMAT
Sbjct: 2581 SPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMAT 2640
Query: 2641 RNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESEEEE 2700
RNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESEEEE
Sbjct: 2641 RNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESEEEE 2700
Query: 2701 EEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRDPSLTPSIGPVSRGM 2760
EEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRDPSLTPSIGPVSRGM
Sbjct: 2701 EEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRDPSLTPSIGPVSRGM 2760
Query: 2761 KESISHKIRQEKGTRASNYRLQVRRSFKTWWQKKPQMDLISPLLLPVLLLHPQEKPSDLV 2820
KESISHKIRQEKGTRASNYRLQVRRSFKTWWQKKPQMDLISPLLLPVLLLHPQEKPSDLV
Sbjct: 2761 KESISHKIRQEKGTRASNYRLQVRRSFKTWWQKKPQMDLISPLLLPVLLLHPQEKPSDLV 2820
Query: 2821 FSQELILGPNSETPNLYLERQWEKLEEQLATSAAQLKLSPHLARCHSMAQHVARLVRVLA 2880
FSQELILGPNSETPNLYLERQWEKLEEQLATSAAQLKLSPHLARCHSMAQHVARLVRVLA
Sbjct: 2821 FSQELILGPNSETPNLYLERQWEKLEEQLATSAAQLKLSPHLARCHSMAQHVARLVRVLA 2880
Query: 2881 RPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDASWHAGMLSQP 2940
RPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDASWHAGMLSQP
Sbjct: 2881 RPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDASWHAGMLSQP 2940
Query: 2941 VALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQ 3000
VALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQ
Sbjct: 2941 VALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQ 3000
Query: 3001 RFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHL 3060
RFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHL
Sbjct: 3001 RFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHL 3060
Query: 3061 EGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLCPALPLVTPKTFLDFLD 3120
EGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLCPALPLVTPKTFLDFLD
Sbjct: 3061 EGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLCPALPLVTPKTFLDFLD 3120
Query: 3121 TFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQ 3180
TFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQ
Sbjct: 3121 TFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQ 3180
Query: 3181 QLEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAFLEPLSQLQVADF 3240
QLEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAFLEPLSQLQVADF
Sbjct: 3181 QLEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAFLEPLSQLQVADF 3240
Query: 3241 EEIRSYRAPPESVVRVTDAMCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELI 3300
EEIRSYRAPPESVVRVTDAMCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELI
Sbjct: 3241 EEIRSYRAPPESVVRVTDAMCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELI 3300
Query: 3301 KLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTRE 3360
KLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTRE
Sbjct: 3301 KLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTRE 3360
Query: 3361 QARLGYYQFQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPM 3420
QARLGYYQFQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPM
Sbjct: 3361 QARLGYYQFQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPM 3420
Query: 3421 RAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPD 3480
RAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPD
Sbjct: 3421 RAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPD 3480
Query: 3481 DVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLL 3540
DVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLL
Sbjct: 3481 DVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLL 3540
Query: 3541 LRSPTHYSSCRWPLLLDPSNEALIWLDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTD 3600
LRSPTHYSSCRWPLLLDPSNEALIWLDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTD
Sbjct: 3541 LRSPTHYSSCRWPLLLDPSNEALIWLDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTD 3600
Query: 3601 MKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPS 3660
MKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPS
Sbjct: 3601 MKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPS 3660
Query: 3661 LPYLSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPPQVQPGF 3720
LPYLSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPPQVQPGF
Sbjct: 3661 LPYLSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPPQVQPGF 3720
Query: 3721 CLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDL 3780
CLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDL
Sbjct: 3721 CLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDL 3780
Query: 3781 KIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQK 3840
KIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQK
Sbjct: 3781 KIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQK 3840
Query: 3841 LQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHG 3900
LQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHG
Sbjct: 3841 LQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHG 3900
Query: 3901 EDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPG 3960
EDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPG
Sbjct: 3901 EDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPG 3960
Query: 3961 LAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLS 4020
LAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLS
Sbjct: 3961 LAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLS 4020
Query: 4021 STVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTMPFK 4080
STVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTMPFK
Sbjct: 4021 STVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTMPFK 4080
Query: 4081 HSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVS 4140
HSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVS
Sbjct: 4081 HSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVS 4140
Query: 4141 TLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVST 4200
TLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVST
Sbjct: 4141 TLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVST 4200
Query: 4201 VHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQ 4260
VHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQ
Sbjct: 4201 VHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQ 4260
Query: 4261 ALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPRAAMQELAAS 4320
ALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPRAAMQELAAS
Sbjct: 4261 ALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPRAAMQELAAS 4320
Query: 4321 VFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECK 4380
VFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECK
Sbjct: 4321 VFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECK 4380
Query: 4381 AQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLR 4440
AQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLR
Sbjct: 4381 AQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLR 4440
Query: 4441 QRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQ 4500
QRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQ
Sbjct: 4441 QRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQ 4500
Query: 4501 RDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQ 4560
RDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQ
Sbjct: 4501 RDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQ 4560
Query: 4561 LLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSS 4620
LLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSS
Sbjct: 4561 LLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSS 4620
Query: 4621 QLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSP 4680
QLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSP
Sbjct: 4621 QLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSP 4680
Query: 4681 LPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTC 4740
LPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTC
Sbjct: 4681 LPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTC 4740
Query: 4741 VQRRVHVCSPPLS 4753
VQRRVHVCSPPLS
Sbjct: 4741 VQRRVHVCSPPLS 4753
>gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens]
Length = 597
Score = 1219 bits (3154), Expect = 0.0
Identities = 596/596 (100%), Positives = 596/596 (100%)
Query: 1 MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60
MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL
Sbjct: 1 MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60
Query: 61 LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120
LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT
Sbjct: 61 LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120
Query: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE
Sbjct: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
Query: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240
LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV
Sbjct: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240
Query: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300
EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV
Sbjct: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300
Query: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360
APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF
Sbjct: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360
Query: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV
Sbjct: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
Query: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480
SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV
Sbjct: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480
Query: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540
QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI
Sbjct: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540
Query: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQV 596
TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQV
Sbjct: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQV 596
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 298 bits (764), Expect = 7e-80
Identities = 366/1691 (21%), Positives = 665/1691 (39%), Gaps = 249/1691 (14%)
Query: 1018 QQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSP---VLQ 1074
+Q +W + + EW F P E G +++ A+ T LE P V+
Sbjct: 889 KQLLWDSFSEWDKLQQEWLKSKFDCLDP----EVLNGQVSKYAKFVTQLEKGLPPNSVVP 944
Query: 1075 HCMRILGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEF 1134
+ + + LP++ L + ++ + + + + + LTL +L + +F
Sbjct: 945 QLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDF 1004
Query: 1135 ADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSP 1194
I + + + +++++ W+ + +L R + V
Sbjct: 1005 GQEIQDISGQASGEAALEAILKKVEDSWKTTEFVIL------------PHRDSKDV---- 1048
Query: 1195 QWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGAL 1254
FIL ++Q + +S ++ + + G L EW +
Sbjct: 1049 -----------FILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQT 1097
Query: 1255 LEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVP 1314
LE WLT Q+ W++L + + IQ F +D ++ +MR +P
Sbjct: 1098 LEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNR--------LP 1149
Query: 1315 SAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAAR 1374
+A R+ G L + Q + L+ I LE+ L FPR +FLS+ EL+ +LA
Sbjct: 1150 NALRAATQPG--LLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQT 1207
Query: 1375 LESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKL 1434
Q +R+CF + + F P E + P + LA+L GE V L
Sbjct: 1208 RNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSL 1267
Query: 1435 QGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQL 1494
L ++ +WL +E+ + +L + + +A Q KL
Sbjct: 1268 GKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIA----------------DYQGKLRTD- 1310
Query: 1495 YVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNF----- 1549
W+ V P Q +L +++W ++ E L + H ++ L NF
Sbjct: 1311 ----WV--VAGHPSQVILTVSQIMWCRDLTECL--------ETEHSNHIQALKNFEKVNF 1356
Query: 1550 --MRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKY 1607
+ A A G SLP + + ++L+AL+ + V RDI L Q +V + F W RQL+Y
Sbjct: 1357 ERLNALAAIVQG-SLPKLHR-NILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRY 1414
Query: 1608 HLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLL 1665
+ + C + + Y YEYLG PRL P L
Sbjct: 1415 YW----------------------DIDLDNCVARMALSQYTYGYEYLGACPRLVITP--L 1450
Query: 1666 PERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNY 1725
+R L L+ AL+ G GP G GK LA+AL Q V+ CS ++ + + +
Sbjct: 1451 TDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRF 1510
Query: 1726 LNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLL 1785
+G Q GAW ++ +++ +LS + Q+L TI + L
Sbjct: 1511 FSGLAQSGAWCCFDEFNRIDIEVLSVIAQQL------------------ITIRNAKAAKL 1552
Query: 1786 GSSFFEKHHVSVRLGYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLG 1842
FE + + + + + A + +P NL L RP A+ +P+ +AE+ L
Sbjct: 1553 SRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYS 1612
Query: 1843 AGMRDAFQMATRLSKFFSLERELVS--GPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKP 1900
G + +A ++++ + L E +S + +K +L + ++ +E P +
Sbjct: 1613 EGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVL---VMAGSLKRENPDLNED 1669
Query: 1901 RSL-AAIEEAALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEE 1959
L A++++ L P F + L G++ LFP V Y +++ +V+
Sbjct: 1670 VVLIRALQDSNL---PKFLTDDAL---LFSGIISDLFPG---VQIPEHDYGILQSTIVDV 1720
Query: 1960 LQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTS 2019
+ + L P ++ + Q + + G++L+GP G GKTT + L + L +
Sbjct: 1721 MNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKL-GIE 1779
Query: 2020 TQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEES 2077
Q V+ L P ++ E G + W G+ +RAA + K
Sbjct: 1780 NSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHK------ 1833
Query: 2078 IGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPT 2137
WII DG + W++++ +L + L L + ++I P +L EV D SP
Sbjct: 1834 -----WIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPA 1888
Query: 2138 VVGCCALVWCGGEQ-TWQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQ 2196
V C +V+ E+ W + M + +L T + ++ + V L F+ +
Sbjct: 1889 TVSRCGMVFVDPEELKWMPYVKTWMKGI--SKKLTEETQEYILNLFQRYVDEGLHFINKK 1946
Query: 2197 GVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFR 2256
++ QV +++VT++ +L SL+
Sbjct: 1947 CSQAIPQV--------DISKVTTLCCLLESLI---------------------------- 1970
Query: 2257 SSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSIS 2316
L + V+ ++ + + + +F+F +W G +L ++ FDTFIR +
Sbjct: 1971 ------LGKDGVNL--AMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIR---T 2019
Query: 2317 RLSNYPEP--PPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGTLGTFH---PSIQTERLL 2371
+ + P+ P S ++ +H+ + L P+ + + F P+ T R
Sbjct: 2020 QFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYG 2079
Query: 2372 YVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEP-HHPYIYSPIHPAFSSSHLRLLLSRGI 2430
Y+++ LL+ VL G GKS + L+ Y P++ FS+ I
Sbjct: 2080 YLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEII 2139
Query: 2431 QGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTL 2489
+ + + + ++ ++DL++ D S QP +E LRQ D G Y + L
Sbjct: 2140 ESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS-QPPIELLRQYQDFGGFYDRNKL 2198
Query: 2490 ELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLER 2549
+ +Q V ++ PG P+ PR R F++L L ++ +L + I+ +L
Sbjct: 2199 FWKEIQ-DVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSD 2257
Query: 2550 FPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTG 2609
FP ++ A +V ASVE + + +P+P HY F+L +S
Sbjct: 2258 FPPAVKQ--TASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLS-------------- 2301
Query: 2610 SRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCA 2669
+ V G+ + + RL+ HE QR F DRL + ++ Y
Sbjct: 2302 --------------KCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFH 2347
Query: 2670 KLLLVVAQSVF 2680
+L +A F
Sbjct: 2348 VILTEMANKHF 2358
Score = 139 bits (349), Expect = 9e-32
Identities = 156/718 (21%), Positives = 289/718 (40%), Gaps = 76/718 (10%)
Query: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSG---SEEAILQC 2926
+HV+R+ R++ + R + LL+ G GTG+ + LA+ IC + + ++ +
Sbjct: 2427 EHVSRIARMIRQERGNALLV-GVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHED 2485
Query: 2927 LRDASWHAGMLSQPVALLVPSGVDLTT--LHRLLALATSGSFPGQYTEADLDRI-GEHLP 2983
LR AG+ + + L + L + + SG P + + +L+++ P
Sbjct: 2486 LRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRP 2545
Query: 2984 R-ENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042
R + +G+ + + E V Q F +V LH+ + + +F L+ T ID
Sbjct: 2546 RAKEVGISEGNRDE-VFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCT--ID 2602
Query: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102
+ W + AL V++ +D G+ +L+ +P + +HLS + E
Sbjct: 2603 WFVQWPREALLSVSKTFFS-----QVDAGN---EELKEKLPLMC---VNVHLSVSSMAER 2651
Query: 3103 LCPALP---LVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHAN 3159
L TP ++L+ ++ +L + + +I + RV+N L L N
Sbjct: 2652 YYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKL--------LETN 2703
Query: 3160 LIFD--------LEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQRD 3211
++ D LE L + + ++L + Q + E + A +
Sbjct: 2704 ILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQ 2763
Query: 3212 ALQAQREAFLEQMSKAF---LEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHET 3268
A+ + L++ A + L L AD EIR + PP+ V+ V +A+ L + +
Sbjct: 2764 AIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKP 2823
Query: 3269 GWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAA 3328
W SAKQLL +F + L+ + KE I L KL + P + VS+ S+
Sbjct: 2824 DWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCM 2883
Query: 3329 WLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDA 3388
W+ A+ Y P L+ +A L A L Q ++ + AL +
Sbjct: 2884 WVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKG 2943
Query: 3389 QASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAI 3448
+AKT++ + + AAL W +QK + + G+ + +A +
Sbjct: 2944 VNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACV 3003
Query: 3449 IYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPF 3508
Y G F RQ L++ W+ C+ + + P F
Sbjct: 3004 AYYGAFTAQYRQSLIECWIQDCQSLEIPIDPS---------------------------F 3036
Query: 3509 SILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
S++++L E QW+ + P+ + G+L+ RWPL++DP ++A W+
Sbjct: 3037 SLINILGDPYEIRQWNTDGLPRDLISTENGILVT-----QGRRWPLMIDPQDQANRWI 3089
Score = 103 bits (258), Expect = 3e-21
Identities = 196/1024 (19%), Positives = 382/1024 (37%), Gaps = 104/1024 (10%)
Query: 3745 LNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLF 3804
+ +++ + LE+Q+L +++ E P LE + L +R ++ EE++L ML
Sbjct: 3186 VTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFT 3245
Query: 3805 QNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKAL 3864
+ + + ++ ++ EE E + V YRPV G M +
Sbjct: 3246 SEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVI 3305
Query: 3865 SQLQNLLPLFCMSPENWLAVTKQALD-SMKPREINHGEDLASHLLQLRAHLTRQLLGSTV 3923
+ L + P++ S + + + ++ S+K + D+ L A++
Sbjct: 3306 ASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVN-------- 3357
Query: 3924 TALGLTQVP--LVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARPAW 3981
+ GL + + + + +++ G S+ E G A KP + W
Sbjct: 3358 VSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAP-----W 3412
Query: 3982 LGPKAWHEC-EMLELLPPFVGLCASLAGHSSA--------------WQAYLSLS------ 4020
L W C ++ E P F GL ++ H + W+ Y +
Sbjct: 3413 LPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHM 3472
Query: 4021 -STVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYA--PTM 4077
P LS KLIL + + E + AL DF LG+ E PT+
Sbjct: 3473 RQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTL 3532
Query: 4078 PFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSV 4137
++ P++ +L S P+ Q+ A + ++ +Q I+LG + P++
Sbjct: 3533 -YQDMSCNTPLVFIL------STGSDPMGAFQRFARESGYSER-VQSISLG-QGQGPIAE 3583
Query: 4138 VVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESR- 4196
+ + AM G+W+ L NCHL W + +L+ + D L P +
Sbjct: 3584 KM--VKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTF 3641
Query: 4197 NVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQ 4256
V+ + ++ P A++ T+ + P F+ +++ LG + +Q+++
Sbjct: 3642 PVTVLQNSVKVTNEPPKGLRANIRRAFTEMT-PSFFEENI-LG-------KKWRQIIF-- 3690
Query: 4257 PPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPRAAMQE 4316
+ H ++ R+ +G ++ L P A+
Sbjct: 3691 ------GICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKEGKIPWDALIY 3744
Query: 4317 LAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAM 4376
+ + YGG + D+ D+ L ++ + SP + ++ + M D++
Sbjct: 3745 ITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPM-------ADSL 3797
Query: 4377 AECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAE 4436
E K + LP +P + G+ E +++ L++ + P R + E
Sbjct: 3798 QEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQP-------RSSTGGE 3850
Query: 4437 RRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNAR-RPLEGVLETEALELSQL 4495
+ +VQ + S+Q + + + + V R L VL E + L
Sbjct: 3851 GKSNDEIVQ--ELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNL 3908
Query: 4496 VGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQL 4555
+ + L+ L + + G S V ++ ++P W A +P W++ L
Sbjct: 3909 LKLIHTSLETLNKAIAGF-VVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDL 3967
Query: 4556 SRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSR 4615
R + +L G S + +S F P+ L A N+P
Sbjct: 3968 ILRTSFVDLWLKRGQPKS-------YWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY 4020
Query: 4616 GSVSSQLQYKRLEMNSNPLHFRVENGPNPTV--PERGLLLIGLQVLHAEWDPIAGALQDS 4673
+ + + + + F E + + PE G+L+ G+ + + WD ++D+
Sbjct: 4021 SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA 4080
Query: 4674 PSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY-MGGPLGTAKL--QSRNIVMHLP 4730
Q +P+ PV P + P+P T+Y CP+Y G GT S N V+ +
Sbjct: 4081 LPGQMNPVLPV--VHFEPQQNYKPSP---TLYHCPLYKTGARAGTLSTTGHSTNFVVTVL 4135
Query: 4731 LPTK 4734
LP+K
Sbjct: 4136 LPSK 4139
Score = 62.8 bits (151), Expect = 8e-09
Identities = 64/294 (21%), Positives = 124/294 (42%), Gaps = 30/294 (10%)
Query: 284 LKMERYLKKIHFLYLNVAPSRY---FRPYSLMVVPPDKVNP-EHYIFSPFGILHVHPVEG 339
+K+ R + + FLY+ A R + Y+L VV + +N ++Y S + H++ E
Sbjct: 190 IKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRAVTHIYN-ED 248
Query: 340 SETMTLGTWHHHCVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLA 399
E + + W + ++L IP F K+F+ W+KNVR + + QK L+ +L +
Sbjct: 249 IEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIV 308
Query: 400 VPHFGAGLLHISRL-----------LQELHSVSWLPQELDRCYELLDLQTALAEEKHKAL 448
PH LL I+ L +++ H+ + + + L ++ L E +++A
Sbjct: 309 NPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERLGEFRNEAK 368
Query: 449 RLLHRCLNLCTSILRLVHED-------TYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHK 501
++ R V +D YH Q + + T Y +
Sbjct: 369 YVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPT-----YGDSEKMT 423
Query: 502 QLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
EQ K+ + ++L F RL DY+I ++ + + S + ++ ++ P
Sbjct: 424 YTEQASKR--HYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTP 475
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 261 bits (668), Expect = 9e-69
Identities = 339/1668 (20%), Positives = 659/1668 (39%), Gaps = 269/1668 (16%)
Query: 1019 QRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHS-PVLQHCM 1077
Q+IW + R EN +EWK F + G +++ + + +++
Sbjct: 1231 QQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTR 1290
Query: 1078 RILGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR 1137
+ +F+ +PL++ L + + + + + Q E TL Q++ + + ++
Sbjct: 1291 SKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEK 1350
Query: 1138 INQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWE 1197
I ++ + + + + ++ + + W+ QL + VPY
Sbjct: 1351 IGEISASATKELAIEVALQNIAKTWDVTQLDI------VPY------------------- 1385
Query: 1198 VVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEV 1257
KD G L + +++++ LS + A K W + + ++E+
Sbjct: 1386 ---KDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEM 1442
Query: 1258 WLTFQQKWIFLNKVL--HEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPS 1315
LT Q++W++L + +++ Q PN ++ F ++ ++ +M D L
Sbjct: 1443 ILTVQRQWMYLENIFLGEDIRKQLPNE--STLFDQVNSNWKAIMDRMNKDNNAL------ 1494
Query: 1316 AERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARL 1375
RS + G L L++ ++ LE I SL+ L FPR +FLS+ +L+ +L
Sbjct: 1495 --RSTHHPGL-LDTLIEMNTI-LEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSR 1550
Query: 1376 ESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQ 1435
Q +++CF ++ + + P+++ EA+ + GE +
Sbjct: 1551 NPEAVQPHLKKCFDNIKLLRIQKV-----------GGPSSKW--EAVGMFSGDGEYIDFL 1597
Query: 1436 GPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLY 1495
+ L + WL +E+ +R+ L +L+ C A K L K++K +
Sbjct: 1598 HSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLA----------LRKFLNKRDK-----W 1642
Query: 1496 VQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLA----MVSMHMRKLEVLVNFMR 1551
V+ W Q V+ A ++ W A++ + LL A + M ++ +L +
Sbjct: 1643 VKEWAG-------QVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSE 1695
Query: 1552 AQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGS 1611
A R + L + + ++ AL+ + + RD+ + L + + D+ F W+ QL+++
Sbjct: 1696 AIRGN-----LTKIMRLKIV-ALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYW-- 1747
Query: 1612 PHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPAL 1671
E L C I F YNYEYLG + + L +R +
Sbjct: 1748 ------------------EKDLDD--CVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYM 1787
Query: 1672 VLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQ 1731
L AL G+ GP G GK V L +ALG ++++ CS ++ + + +G Q
Sbjct: 1788 TLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQ 1847
Query: 1732 GGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFE 1791
GAW ++ +++ +LS + H + L A+ G + F
Sbjct: 1848 TGAWGCFDEFNRINIEVLSVVA------HQILCILSALAA--------------GLTHFH 1887
Query: 1792 KHHVSVRLGYGCLLVLR-----ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMR 1846
+ L + C + + A + +P NL + RP+A+ +PD +AE+ L G G
Sbjct: 1888 FDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFG 1947
Query: 1847 DAFQMATRLSKFFSLERELVSGP------LPCRLPLLKQILEDTIRTLNVTKEEPKCQKP 1900
+ +A ++ +SL + +S L LL+ + ++T EE
Sbjct: 1948 NCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSM 2007
Query: 1901 RSLAAIEEAALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEEL 1960
R + I + + +PLF+ ++ LFP+ + + Y ++ V +E+
Sbjct: 2008 RDMN-IAKLTSVDAPLFN-----------AIVQDLFPNIELPVID---YGKLRETVEQEI 2052
Query: 1961 QQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTST 2020
+ +GL +P L + QL + + +++G GSGKT W L Q L+++
Sbjct: 2053 RDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRIL---QASLSSLCRAGD 2109
Query: 2021 QGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESI 2078
V L P LS E G + S W GI V+R A +K
Sbjct: 2110 PNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEK------- 2162
Query: 2079 GIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTV 2138
WI+ DG + W++++ ++ + L+L +G++IA P LL EV D SP
Sbjct: 2163 ----WILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT 2218
Query: 2139 VGCCALVWCG-GEQTWQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFL--TC 2195
V C +V+ + W+ + + + P V L M E L+ L F C
Sbjct: 2219 VSRCGMVYTDYADLGWKPYVQSWLEKRP------KAEVEPLQRMFEKLINKMLAFKKDNC 2272
Query: 2196 QGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSF 2255
+ + L + G +TS+ ++ +L E P D +++
Sbjct: 2273 KELVPLPEYSG----------ITSLCKLYSAL------ATPENGVNPAD-------GENY 2309
Query: 2256 RSSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSI 2315
+ + +F+F++IW A + D+++R+
Sbjct: 2310 VT------------------------MVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIE 2345
Query: 2316 SRLSNYPEPPPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGTLGTFH----PSIQTERLL 2371
P V++ V P+ + F + S F+ P++ T R
Sbjct: 2346 GSF------PNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYN 2399
Query: 2372 YVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQ 2431
Y+V L++ P+LL G TGK++ + +++ +S + S+ + I+
Sbjct: 2400 YLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIE 2459
Query: 2432 GQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMDGTVYAHSTLEL 2491
+ + + + S++ ++DL++ D S QP LE +R +D + T +
Sbjct: 2460 SRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGS-QPPLELIRLWIDYGFWYDRTKQT 2518
Query: 2492 QTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFP 2551
+ +A + PG + PRL F ++ + T++ ++ +I L+ F
Sbjct: 2519 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE 2578
Query: 2552 SVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSR 2611
E + + + A+++ + V F+P+P HY F+L +S + + ++
Sbjct: 2579 --EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGM-----LRANK 2631
Query: 2612 GFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRL 2659
F D ++ RLW+HE R F DRL
Sbjct: 2632 DFHD-----------------------TKSSITRLWIHECFRVFSDRL 2656
Score = 145 bits (365), Expect = 1e-33
Identities = 175/755 (23%), Positives = 311/755 (41%), Gaps = 94/755 (12%)
Query: 2845 LEEQLATSAAQLKLSP-----HLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHT 2899
L+ + T+ + LSP L +H+ R+VRV+ +PR + +LL G G+GR +
Sbjct: 2712 LKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGN-MLLVGIGGSGRQS 2770
Query: 2900 AITLASSICQAHFFHLPSGS---EEAILQCLRDASWHAGM-LSQPVALLVPSGV-DLTTL 2954
LASSIC F + ++ ++ AG+ L + V + + D + L
Sbjct: 2771 LARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFL 2830
Query: 2955 HRLLALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFF 3014
+ + +SG P Y + + I H+ + + + + ++V ++LH+
Sbjct: 2831 EDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVL 2890
Query: 3015 LI---GDKQAH--KQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLD 3069
+ GD + +Q P+ + +I+ + W Q AL +VA+ L G +D
Sbjct: 2891 CLSPMGDPFRNWIRQYPALV-------NCTTINWFSEWPQEALLEVAEKCLIG-----VD 2938
Query: 3070 DGSWKYPDLQASIP-SVAKAMALIHLSATHYHEHLCPALP---LVTPKTFLDFLDTFLML 3125
G+ Q +I VA+ +H S Y + + L VTP +L+ L + L
Sbjct: 2939 LGT------QENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKL 2992
Query: 3126 ---QQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQL 3182
++Q +L NK + ++ R ++ + LE L+D+ K ++ FQ+Q
Sbjct: 2993 LGEKRQELLAQANKLRTGLFKIDETREKVQ--------VMSLE--LEDAKKKVAEFQKQC 3042
Query: 3183 EQSKLLYKQQLEECRHQENLI----ENLARQRDALQAQREAFLEQMSKAF------LEPL 3232
E+ ++ QQ E Q+ + E +A + QA + + + +A + L
Sbjct: 3043 EEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRAL 3102
Query: 3233 SQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHETGWASAKQLLCTEDFYQELVFFPKE 3292
L D EI+SY PP V V A+ L +E WA AK+ L ++F + L+ F K+
Sbjct: 3103 ESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKD 3162
Query: 3293 KITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQ 3352
I+D L K+ P + VS A SL W+ A+ YG + P + +
Sbjct: 3163 NISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNA 3222
Query: 3353 VEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPM 3412
A L +QA L Q + +E E L K ++ A + K + + +
Sbjct: 3223 ALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGML 3282
Query: 3413 KAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDE-WLALCR 3471
+ L W +Q L+ + GD LL +A + Y+GPF R E++++ W+
Sbjct: 3283 VSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIW 3342
Query: 3472 GFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQA 3531
Q P F+I + L + ++ W+ P
Sbjct: 3343 ELQVPCSPS---------------------------FAIDNFLCNPTKVRDWNIQGLPSD 3375
Query: 3532 KSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
+ G+++ RW L++DP +AL W+
Sbjct: 3376 AFSTENGIIVTRGN-----RWALMIDPQAQALKWI 3405
Score = 99.4 bits (246), Expect = 8e-20
Identities = 215/1059 (20%), Positives = 375/1059 (35%), Gaps = 128/1059 (12%)
Query: 3678 LQEAAACGLPVLLTNVE----------LGLGCEELQW-LLQREQLSPPQVQPGFCLYLST 3726
L+ A G PVLL NV+ L + LL R + F Y++T
Sbjct: 3428 LEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITT 3487
Query: 3727 TLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALD 3786
LS E +++ + + LE Q+L ++ +E PELE + L I
Sbjct: 3488 KLS----NPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAA 3543
Query: 3787 TCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVL 3846
+ ++ E+ +L +L + + + ++ ++ E E ++ +
Sbjct: 3544 GKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLA 3603
Query: 3847 WAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASH 3906
YRP + L+ + + P++ S + ++++ ++D K N ED +
Sbjct: 3604 REAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSID--KSHRSNKLEDRIDY 3661
Query: 3907 LLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELE-RLALWPGLAASP 3965
L + + T L L +L+ +GK + E L G+
Sbjct: 3662 LNDYHTYAVYRY---TCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR 3718
Query: 3966 STVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLG 4025
P S +WL W L+ L F GL S + W + + ++
Sbjct: 3719 EGQMDNPCS-----SWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKA 3773
Query: 4026 PAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLG-RPLDENTYAPTMPFKHSQA 4084
PG + +Q++++ R LR + +A + F + LG R ++ + S
Sbjct: 3774 MLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTP 3833
Query: 4085 TQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQ 4144
P++ +L P P++ L L +A ++ ++LG + L +
Sbjct: 3834 RSPLVFILSPGVDPTSALLQLAEHMGMAQRFH-------ALSLGQ---GQAPIAARLLRE 3883
Query: 4145 AMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRD 4204
+ +GHW+ L NCHL W L +L+ E V H
Sbjct: 3884 GVTQGHWVFLANCHLSLSWMPNLDKLV----------------------EQLQVEDPHPS 3921
Query: 4205 FRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPL 4264
FRLWL + + M + L+ + + Q P + L
Sbjct: 3922 FRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKL 3981
Query: 4265 L----LLHGLLLHRQ---------LYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPR 4311
L H +LL R+ +YG S+ L+ L ++ P
Sbjct: 3982 LFSLCFFHSVLLERKKFLQLGWNIIYG--FNDSDFEVSENLLSLYLDEYEE------TPW 4033
Query: 4312 AAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELR 4371
A++ L A + YGG + D DR L + S S P S L T +
Sbjct: 4034 DALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLS--TPFHRLSALETYF----IP 4087
Query: 4372 ELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRG 4431
+ ++A K + LLP P G +++ L L P P +R G
Sbjct: 4088 KDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITP-TRAG 4146
Query: 4432 AQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALE 4491
Q E ++ + V +++ + D E L P+ PL VL E
Sbjct: 4147 GQTREEKVLELAADVKQKIPEMIDY--------EGTQKLLALDPS---PLNVVLLQEIQR 4195
Query: 4492 LSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHW 4551
+ L+ T+ L L + ++G S + + ++ +P W P+ +P W
Sbjct: 4196 YNTLMQTILFSLTDLEKGIQGL-IVMSTSLEEIFNCIFDAHVPPLWGKAYPS-QKPLAAW 4253
Query: 4552 LRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNF 4611
R L+ R + + AS P +F LS F P L A+ +A NV
Sbjct: 4254 TRDLAMRVEQFELW------ASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNV----- 4302
Query: 4612 PGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQ 4671
S S+S + ++ +SN ++ P+ G+ + GL + A WD L
Sbjct: 4303 --SVDSLSWEFIVSTVD-DSNLVY----------PPKDGVWVRGLYLEGAGWDRKNSCLV 4349
Query: 4672 DSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710
++ Q L P A + +YSCP Y
Sbjct: 4350 EAEPMQLVCLMPTIHFRPAESRK----KSAKGMYSCPCY 4384
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 258 bits (658), Expect = 1e-67
Identities = 360/1749 (20%), Positives = 675/1749 (38%), Gaps = 289/1749 (16%)
Query: 964 TQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWH 1023
T++ + +L L + ++ ++ + ++++ PL + V +++W
Sbjct: 815 TEEMKHNVEKLNELSKNLNRAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWS 874
Query: 1024 LYRVISENISEW-KCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSP--VLQHCMRIL 1080
S EW F + +A+E W T + T ++ +P + ++ +
Sbjct: 875 TAYEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKI 934
Query: 1081 GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ 1140
+F+ Y+P+L+ + + + Q + +G ++ E L +L + +F +++
Sbjct: 935 DKFKQYIPILSISCNPGMKDRHWQQISEIVGY-EIKPTETTCLSNMLEFGFGKFVEKLEP 993
Query: 1141 VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD 1200
+ ++ ++ + R++ W + +
Sbjct: 994 IGAAASKEYSLEKNLDRMKLDWVNVTFSFVKY---------------------------- 1025
Query: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
+D+ T IL ++Q + + + + + +W + + L+ WL
Sbjct: 1026 RDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLK 1085
Query: 1261 FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP 1320
Q W++L + I + +F ++D +++LM +V D +L A P
Sbjct: 1086 CQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILV-----AADQP 1140
Query: 1321 YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA 1380
++ + LQ + LE I L L FPR FFLS+ EL+ +L+ +
Sbjct: 1141 -----RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRV 1195
Query: 1381 QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL 1440
Q +++CF + + F TD+ E ++ E + ++ P
Sbjct: 1196 QPHLKKCFEGIAKLEF---------TDNLEIVGMISSEKETVPF-------IQKIYPANA 1239
Query: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLG-EALKQLPKQNKLYLQLYVQHW 1499
+ KWL +E+ + ++ ++ LG EA ++P+ HW
Sbjct: 1240 KGMVEKWLQQVEQMMLASMREVI------------GLGIEAYVKVPR----------NHW 1277
Query: 1500 IDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGG 1559
V +P Q V+ + W E+ +AL E L + ++ +V +R + +S
Sbjct: 1278 ---VLQWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQIVQLVRGKLSS--- 1331
Query: 1560 QSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSP 1619
R T L AL V+ V RD+ L + +VSDL DF W+ QL+Y+ + +
Sbjct: 1332 ----GARLT--LGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDV----- 1380
Query: 1620 LQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLAL 1677
+ ++ LY YEYLG PRL P L +R L+ AL
Sbjct: 1381 -------------------QVQIITTEALYGYEYLGNSPRLVITP--LTDRCYRTLMGAL 1419
Query: 1678 EEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLL 1737
+ G GP G GK LA+AL +Q V+ CS ++ + + + G Q GAW
Sbjct: 1420 KLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWAC 1479
Query: 1738 LEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSV 1797
++ +++ +LS + Q++ + Q R T FE +S+
Sbjct: 1480 FDEFNRIEVEVLSVVAQQI-------LSIQQAIIRKLKTF-----------IFEGTELSL 1521
Query: 1798 RLGYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATR 1854
+ + A + +P NL L R VA+ +PD + E++L G D+ +A +
Sbjct: 1522 NPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQK 1581
Query: 1855 LSKFFSLERELVSGP--LPCRLPLLKQILEDTIR-TLNVTKEEPKCQKPRSLAAIEEAAL 1911
+ + L E +S + +K +L L +E R+L + A
Sbjct: 1582 IVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKF 1641
Query: 1912 LRS--PLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSP 1969
L PLF +G++ LFP VL +P Y++ ++ + ++++ L P P
Sbjct: 1642 LAQDVPLF-----------QGIISDLFPGV--VLPKP-DYEVFLKVLNDNIKKMKLQPVP 1687
Query: 1970 DILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAA---MEDTSTQGCQPV 2026
+G + Q+ + + G +++G GKT+ + L L A ME+ + V
Sbjct: 1688 WFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFA------V 1741
Query: 2027 EITHLYPSGLSPQEFLGWLE--GSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWI 2084
E + P ++ + G + W G+ R Q +++ R+ WI
Sbjct: 1742 EYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFRE--QASSLSDDRK---------WI 1790
Query: 2085 ICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCAL 2144
I DG + W++++ +L + +L L SG+ I L+ E AD SP V C +
Sbjct: 1791 IFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGM 1850
Query: 2145 VWCGGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRF--LTCQGVSSL 2201
++ Q W+ + + M +LP +H+ + +N M LV L F L C+ V
Sbjct: 1851 IYMEPHQLGWKPLKDSYMDTLPSSLTKEHKEL--VNDMFMWLVQPCLEFGRLHCKFVVQT 1908
Query: 2202 LQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSS 2261
+H SM R+ SLLD ++EE+ E L SS+
Sbjct: 1909 SPIH----------LAFSMMRLYSSLLDEIRAVEEEEMELGEGL-----------SSQQI 1947
Query: 2262 FLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNY 2321
F L FLF+L+W + + FD F R+ I + +
Sbjct: 1948 F------------------LWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDN 1989
Query: 2322 PEPPPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGTLGTFH------------------- 2362
P S + ++ PE G++ F Y G T+
Sbjct: 1990 HPRPKSVKLTKNNIFPERGSIYDF---YFIKQASGHWETWTQYITKEEEKVPAGAKVSEL 2046
Query: 2363 --PSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVE--VLVEPHHPYIYSPIH--PA 2416
P+++T R + + L P+L G TGKSA +L P + Y+ + I+
Sbjct: 2047 IIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSAR 2106
Query: 2417 FSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLR 2476
S++ + ++ + + + P K +++F ++DL++ + QP +E LR
Sbjct: 2107 TSANQTQDIIMSKLDRRRKGLFGP---PIGKKAVVF-VDDLNMPAKE-VYGAQPPIELLR 2161
Query: 2477 QAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLL 2536
Q +D + + + + + PG + R R ++++ + L
Sbjct: 2162 QWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILT 2221
Query: 2537 ERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSH 2596
+ I+ + V R + LV+A+ + F+P+P HY F+L S
Sbjct: 2222 KIFSSIVDWHFGKGFDVMFLR-YGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSR 2280
Query: 2597 LLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFC 2656
++ + L P+ HL+ V +RLW+HE R F
Sbjct: 2281 VIQGVLLCPH--------------THLQDV--------------EKCIRLWIHEVYRVFY 2312
Query: 2657 DRLDSPRER 2665
DRL +R
Sbjct: 2313 DRLIDKEDR 2321
Score = 127 bits (320), Expect = 2e-28
Identities = 245/1134 (21%), Positives = 422/1134 (37%), Gaps = 178/1134 (15%)
Query: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNV--ELGLGCEELQWLLQREQLSPPQVQPG-- 3719
L+V+ +D L+ A G PVL+ N+ EL E + +Q ++ G
Sbjct: 3101 LAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGEN 3160
Query: 3720 -------FCLYLSTTL-SLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYP 3771
F LY++T L + + +V L + LGL ++Q+L + +E P
Sbjct: 3161 IIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGL-----QDQLLGIVAAKEKP 3215
Query: 3772 ELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRA 3831
ELE + L + + K ++ E+++L +L + ++ L +
Sbjct: 3216 ELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIK-------VLSSSKV 3268
Query: 3832 HCEEL-EGQKLQEMV------LWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAV 3884
EE+ E QK+ M Y+PV H + +S L N+ P++ S ++ +
Sbjct: 3269 LSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINL 3328
Query: 3885 TKQALD-SMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALL 3943
+L S K E+N + + H T + + +L L L + ++
Sbjct: 3329 YMHSLTHSTKSEELN------LRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIM 3382
Query: 3944 QATGKASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLC 4003
+ + +E +W L + + P + A P WL KAW E LP GL
Sbjct: 3383 KQKKEITE----EVWYFLLTGGIALDN-PYPNPA-PQWLSEKAWAEIVRASALPKLHGLM 3436
Query: 4004 ASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSL-LQKLILWRVLRPECLAGALADFTTS 4062
L + W+ L S PG S L+K+++ R LRP+ + A+ +F
Sbjct: 3437 EHLEQNLGEWK--LIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAE 3494
Query: 4063 LLGRPLDENTYAPTMP----FKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQG 4118
+G+ E APT + S P++ +L P P A L K A G
Sbjct: 3495 HMGKLYIE---APTFDLQGSYNDSSCCAPLIFVLSPSADPMAGL------LKFADDLGMG 3545
Query: 4119 QKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRA 4178
+ Q I+LG + P++ + ++ A+ +G W+VL NCHL W L ++ E++
Sbjct: 3546 GTRTQTISLG-QGQGPIAAKM--INNAIKDGTWVVLQNCHLAASWMPTLEKICEEVI--- 3599
Query: 4179 KVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLEL 4238
PES N FRLWL + S P + Q+ + + L
Sbjct: 3600 -------------VPESTNAR-----FRLWL--TSYPSEKFPVSILQNGIKMTNEPPKGL 3639
Query: 4239 GHVLIDSV---ELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWS---QVT 4292
L+ S ++ V + + +L GL + R W+ +
Sbjct: 3640 RANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFN 3699
Query: 4293 LTQVLQTQDQLWASLSN----PRAAMQELAASVFYGGPLGDTEDREALISLTQA------ 4342
+ + + Q+ L++ P A+ L YGG + D +DR L+SL
Sbjct: 3700 ESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEI 3759
Query: 4343 -----CLSPSSGSWVQPH-TPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCG 4396
L+P ++ PH + QS + L LP P + G
Sbjct: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYL-------------------RNLPITAHPEVFG 3800
Query: 4397 LSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDL 4456
L E +++ L + + +P G+ + + + + L QD+
Sbjct: 3801 LHENADITKDNQETNQLFEGVL----LTLPRQSGGSGKSPQEVVEELA---------QDI 3847
Query: 4457 LTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPC 4516
L+ + R + + + + VL E + ++L ++R L L + +KG
Sbjct: 3848 LSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKG-QVL 3906
Query: 4517 PSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDV 4576
S V +++ G++P W + +P ++ L R ++ G
Sbjct: 3907 MSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKG------- 3959
Query: 4577 PERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHF 4636
P VF +S F + L + A +P + + E P
Sbjct: 3960 PPVVFWISGFYFTQSFLTGVSQNYARKYTIP--------------IDHIGFEFEVTPQET 4005
Query: 4637 RVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDS-PSSQPSPLPPVSISTQAPGTSD 4695
+EN P +GL L G A WD + +S P PLP + + PG S
Sbjct: 4006 VMENNPEDGAYIKGLFLEG-----ARWDRKTMQIGESLPKILYDPLPIIWLK---PGESA 4057
Query: 4696 LPAPADLTVYSCPVY----MGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
+ D +Y CPVY G L T S N V+ + LPT + + R V
Sbjct: 4058 MFLHQD--IYVCPVYKTSARRGTLSTTG-HSTNYVLSIELPTDMPQKHWINRGV 4108
Score = 83.6 bits (205), Expect = 4e-15
Identities = 145/732 (19%), Positives = 275/732 (37%), Gaps = 88/732 (12%)
Query: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEA---ILQC 2926
+H++R+ RVL + + H LLL G G+GR +A L++ + + + A +
Sbjct: 2414 EHISRICRVLKQDKGH-LLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWRED 2472
Query: 2927 LRDASWHAGMLSQPVALLVPSGV--DLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPR 2984
L+ G+ ++ L D + + + L +G P + + I E +
Sbjct: 2473 LKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQT 2532
Query: 2985 --ENLGVKQNIKKEMVLQRFHQQVCSHLHLFFL---IGDKQAHKQLPSTLFLRLLQLATA 3039
G K + + F ++V + + IGD ++ +F L+ T
Sbjct: 2533 AARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRL---RMFPSLINCCT- 2588
Query: 3040 SIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAM--ALIHLSAT 3097
ID ++ W AL VA LE V LDD +++ + S+ K ++ LS
Sbjct: 2589 -IDWFQSWPTDALELVANKFLE---DVELDD------NIRVEVVSMCKYFQESVKKLSLD 2638
Query: 3098 HYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTH 3157
+Y++ VTP ++L+ + TF L ++ R L+ L +
Sbjct: 2639 YYNK--LRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVM 2696
Query: 3158 ANLIFDLEQQL----KDSGKSLSMFQQQLEQS---KLLYKQQLEECRHQENLIENLARQR 3210
+ L+ QL +++ K + + + ++ KLL + +E + + + +
Sbjct: 2697 QRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNEC 2756
Query: 3211 DALQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHH---- 3266
+ A+ LE A L L L AD ++S + PP V V +++C +
Sbjct: 2757 EGDLAEAMPALE----AALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPER 2812
Query: 3267 -----------ETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLH-LILKAPGMDDA 3314
E W +K++L F + L + K+ I + ++ + P A
Sbjct: 2813 KPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPA 2872
Query: 3315 ALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQET 3374
++ VS L W+ A+ Y P L++ E L + +L + + +
Sbjct: 2873 VIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLV 2932
Query: 3375 LEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRC 3434
++ AL E+ + + + + + L WT ++L R
Sbjct: 2933 VDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRY 2992
Query: 3435 MTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVS 3494
+ GD LL S + YLG F R + ++WLA C
Sbjct: 2993 TNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAEC------------------------ 3028
Query: 3495 IPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPL 3554
K+ ++ S FS+ L + W P + G+++ +S RW L
Sbjct: 3029 ---KDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVS-----NSRRWAL 3080
Query: 3555 LLDPSNEALIWL 3566
++DP +A W+
Sbjct: 3081 MIDPHGQANKWI 3092
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 225 bits (574), Expect = 7e-58
Identities = 337/1643 (20%), Positives = 631/1643 (38%), Gaps = 304/1643 (18%)
Query: 1082 EFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQV 1141
+F+ ++PL+ + + + + + + +G LQ + T+ L L + DR +
Sbjct: 833 DFKQHIPLIQVICNPGLRPRHWEAMSAIVGY-PLQPSDDSTVSSFLDMNLEPYIDRFEGI 891
Query: 1142 WQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDK 1201
+ ++ ++ + ++ W+A + F++H +
Sbjct: 892 SEAASKEYSLEKAMEKMITEWDA-----VEFVIHSY-----------------------R 923
Query: 1202 DSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTF 1261
++GTFIL+ +Q + + + + K EW + L +L+ WL
Sbjct: 924 ETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKV 983
Query: 1262 QQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPY 1321
Q W++L + I + RF +D +R +MR + D VL++V
Sbjct: 984 QATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTID------ 1037
Query: 1322 FQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQ 1381
+ L++L ++ + LE I+ L L FPR FFLS+ EL+ +L+ + Q
Sbjct: 1038 ---RMLERLKKSNEL-LELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQ 1093
Query: 1382 LWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQ-VEALAVLGAGGEEVKLQGPLPL 1440
+++CF + V F T + +SS + +E ++ A G+
Sbjct: 1094 PHLKKCFEGIAKVEF----TETLDITHMKSSEGEVVELIEIISTAKARGQ---------- 1139
Query: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500
+ KWL LE+ + + +H + G +A K ++ +W
Sbjct: 1140 ---VEKWLVELERVM-INSIHKVTG-------------DATFAYTKYERI-------NW- 1174
Query: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAM---VSMHMRKLEVLVNFMRAQRASQ 1557
V+ +P Q VL ++ W E++ A+ G A+ + R+++ +V +R + + Q
Sbjct: 1175 --VRDWPGQTVLCVSQIFWTKEVQTAI-PMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQ 1231
Query: 1558 GGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPK 1617
+L AL+V+ V RD+ L + +SD +DF W+ QL+Y+ H+ K
Sbjct: 1232 NRVTL---------GALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETK 1282
Query: 1618 SPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLL 1675
++ Y YEYLG PRL P L +R L
Sbjct: 1283 ------------------------MINAGLRYGYEYLGNSPRLVITP--LTDRCYRTLFG 1316
Query: 1676 ALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAW 1735
AL G GP G GK LA+A+ +Q V+ CS ++ L + G L GAW
Sbjct: 1317 ALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAW 1376
Query: 1736 LLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHV 1795
++ +++ +LS + Q++ L A + + T+ +L + +
Sbjct: 1377 ACFDEFNRIDLEVLSVVAQQI-----LTIQRGINAGADILMFEGTELKLDPTCAV---FI 1428
Query: 1796 SVRLGYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRL 1855
++ GY A S +P NL L R VA+ +PD +AE+ L G A ++ ++
Sbjct: 1429 TMNPGY-------AGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKI 1481
Query: 1856 SKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSP 1915
+ L E +S + ++++ K + P EE LLRS
Sbjct: 1482 VATYRLCSEQLSSQHHYDYGM------RAVKSVLTAAGNLKLKYPNE---NEEILLLRSI 1532
Query: 1916 LFSILNGLHLHNL---RGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDIL 1972
+ L H+L G+ LFP L +P Y + + + + L +
Sbjct: 1533 IDVNLPKFLSHDLPLFEGITSDLFPGVK--LPKP-DYNDLLAAIKDNCASMNLQMTAFFS 1589
Query: 1973 GSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGC---QPVEIT 2029
+ Q+ + + G +++G GKT+ + L A+ D +G V+IT
Sbjct: 1590 EKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVL------AGALNDICEKGLMEENKVQIT 1643
Query: 2030 HLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087
L P ++ + G + W G+ RA +K W+I D
Sbjct: 1644 VLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRK-----------WLIFD 1692
Query: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWC 2147
G + W++++ +L + +L L SG+ I P L+ E D SP V C +++
Sbjct: 1693 GPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYM 1752
Query: 2148 GGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHG 2206
W+ ++ + + LP + + + + + +VP ++ F ++ H
Sbjct: 1753 EPHMLGWRPLMLSWVNLLPASVSVIQKEF--IMGLFDRMVPVSVEF---------IRKHT 1801
Query: 2207 QQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRS 2266
++ T++ R L +L+D + ++D V R+ + ++
Sbjct: 1802 KE---LSPTSDTNLVRSLMNLIDCFMD------------DFADEVKLKERNDRETY---- 1842
Query: 2267 QVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPS----RFWPIFDTFIRDSIS------ 2316
L FLF+LIW GA +F I + IS
Sbjct: 1843 --------------SLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNT 1888
Query: 2317 -RLSNYPEPPPS-ALVFDLHVSPEDGTLVPFTGQYLSSHI-----------------KGT 2357
+L + E S AL PE GT+ + Q+++ I K
Sbjct: 1889 FKLQSGTEQTSSKALTVPF---PEKGTIYDY--QFVTEGIGKWEPWIKKLKEAPPIPKDV 1943
Query: 2358 L--GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV-EVLVEPHHPYIYSPIH 2414
+ P++ T R +++LL + +P + G TGKS ++ L+ + IY P+
Sbjct: 1944 MFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLL 2003
Query: 2415 PAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLET 2474
FS+ + + + ++ ++D+++ + QP +E
Sbjct: 2004 INFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPARE-VYGAQPPIEL 2062
Query: 2475 LRQAMDGTVYAH----STLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESM 2530
LRQ +D + S ++L +Q + + PG P+ PR R F ++ +
Sbjct: 2063 LRQWLDHWNWYDLKDCSMIKLVDIQ----IMCAMGPPGGGRNPVTPRYMRHFNIITINEF 2118
Query: 2531 TQATLLERHVPIIQAWLE---RFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHY 2587
+ ++ I+ LE +FP + L +V ++ ++ +P+P HY
Sbjct: 2119 SDKSMYTIFSRILTWHLEICYKFP--DEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHY 2176
Query: 2588 HFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLT---VMMATRNVV 2644
F+L S + ++G CL+ T +
Sbjct: 2177 LFNLRDFSRV-------------------------------IQGVCLSRPETTETTEVIK 2205
Query: 2645 RLWLHEAQRTFCDRLDSPRERSY 2667
RLW+HE R + DRL +RS+
Sbjct: 2206 RLWVHEVLRVYYDRLLDNTDRSW 2228
Score = 103 bits (257), Expect = 4e-21
Identities = 169/767 (22%), Positives = 304/767 (39%), Gaps = 113/767 (14%)
Query: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQL------------ 3711
L V+ ++P+ L+ G PVLL NV EEL +L+ L
Sbjct: 3010 LYVIKLSEPDYVRTLENCIQFGTPVLLENVG-----EELDPILEPLLLKQTFKQGGSTCI 3064
Query: 3712 ----SPPQVQPGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILC 3767
S + P F Y++T L E + +L+ + E +++Q+L ++
Sbjct: 3065 RLGDSTIEYAPDFRFYITTKLR----NPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120
Query: 3768 REYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNP---KRQKPAKFLRNIVRAQG 3824
+E P+LE Q L ++ + + ++ E+++L +L + + K L +
Sbjct: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180
Query: 3825 KLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAV 3884
++ Q + EE E +K+ + YRP+ H + +L+ L N+ P++ S ++ +
Sbjct: 3181 EISQKQEVAEETE-KKIDTTRMG--YRPIAIHSSILFFSLADLANIEPMYQYSLTWFINL 3237
Query: 3885 TKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQ 3944
++++ + EI LA L L+ H T L + +L L + LL
Sbjct: 3238 FILSIENSEKSEI-----LAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLL 3292
Query: 3945 ATGKASELE-RLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLC 4003
++ E R L G+ P +++ WL K+W E L+ LP F +
Sbjct: 3293 HERAINKAEWRFLLTGGIGLD------NPYANLC--TWLPQKSWDEICRLDDLPAFKTIR 3344
Query: 4004 ASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSL 4063
W+ P + + Q++++ R LRP+ + L +F +
Sbjct: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404
Query: 4064 LGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQL 4122
LGR ++ + F S P++ +L P P A L K A G +L
Sbjct: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAAL------LKFADDQGYGGSKL 3458
Query: 4123 QVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVA 4182
++LG + P+++ + L +A+ EG W+VL NCHL W L ++ EL
Sbjct: 3459 SSLSLG-QGQGPIAMKM--LEKAVKEGTWVVLQNCHLATSWMPTLEKVCEEL-------- 3507
Query: 4183 DLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE----- 4237
PES H DFR+WL + S + P + Q+ + + N++ +
Sbjct: 3508 ---------SPES-----THPDFRMWL--TSYPSPNFPVSVLQNGVKM-TNEAPKGLRAN 3550
Query: 4238 -LGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWS---QVTL 4293
+ L+D + + + P + LL+GL L R + W+ +
Sbjct: 3551 IIRSYLMDPISDPEFFGSCKKPEEFKK--LLYGLCFFHALVQERRKFGPLGWNIPYEFNE 3608
Query: 4294 TQVLQTQDQLWASLSN----PRAAMQELAASVFYGGPLGDTEDREALISLTQACLSP--- 4346
T + + QL L+ P A++ + YGG + D DR L S+ +P
Sbjct: 3609 TDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELV 3668
Query: 4347 --------SSGSWVQP-------HTPQSLLATLMPLPELRELDAMAE 4378
SSG + P + + L P PE+ ++A A+
Sbjct: 3669 ENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANAD 3715
Score = 102 bits (253), Expect = 1e-20
Identities = 166/747 (22%), Positives = 281/747 (37%), Gaps = 116/747 (15%)
Query: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRD 2929
+H++R+ R+L +PR H LL+ G G+GR + LA+ + F + I +
Sbjct: 2321 EHISRISRILKQPRSHALLV-GVGGSGRQSVTRLAAHMADYSVFQVE------ISKGYDT 2373
Query: 2930 ASWHAGM--LSQPVALLVPSGVDLTT---------LHRLLALATSGSFPGQYTEADLDRI 2978
WH + + + A GV L T L + L +G P + + I
Sbjct: 2374 TEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEI 2433
Query: 2979 GE---HLPRENLGVKQNIKKEMVLQRFHQQVC-SHLHLFFL---IGDKQAHKQLPSTLFL 3031
+ L R+ KQ + L C S LH+ IGD ++ F
Sbjct: 2434 CDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRK---FP 2490
Query: 3032 RLLQLATASIDRYEPWDQAALAKVAQHHLEGAQ-SVPLDDGSWKY-PDLQASIPSVAKAM 3089
L+ T ID ++ W + AL VA LE + S + DG S ++K+
Sbjct: 2491 ALVNCCT--IDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSF 2548
Query: 3090 ALIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRM 3149
+ L +Y VTP ++L+ + TF +L ++ ++ +R + LE L
Sbjct: 2549 -FVELQRYNY----------VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDS 2597
Query: 3150 LIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQ 3209
+ T + L QLK + K + +E+ + + + + E + A
Sbjct: 2598 ASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMA 2657
Query: 3210 RDALQAQREAFLE---QMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMC----- 3261
A++ + +A L + ++ L L L D ++S ++PP V V +A+C
Sbjct: 2658 SKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGI 2717
Query: 3262 --DLFHHETG--------WASAKQLLCTEDFYQELVFFPKEKITDS--ELIKLHLILKAP 3309
D TG W AK+LL F Q L + K+ I + +I+ + I P
Sbjct: 2718 KADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPN-P 2776
Query: 3310 GMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLT-------REQA 3362
+R S A L W+ A+ Y P + L E L ++QA
Sbjct: 2777 DFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQA 2836
Query: 3363 RLGYYQ---FQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTP 3419
L Q + Q+TLE N + D + + +K L +A+ + L
Sbjct: 2837 ALKEVQDKLARLQDTLELN---KQKKADLENQVDLCSKKLERAE-------QLIGGLGGE 2886
Query: 3420 MRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGP 3479
W+ +L + + GD L+ S + YLG F RQ EW LC+G
Sbjct: 2887 KTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSD 2946
Query: 3480 DDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGL 3539
D S++ L W+ P + G+
Sbjct: 2947 D---------------------------CSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGI 2979
Query: 3540 LLRSPTHYSSCRWPLLLDPSNEALIWL 3566
++ ++ RWPL++DP ++A W+
Sbjct: 2980 II-----MNARRWPLMIDPQSQANKWI 3001
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 218 bits (556), Expect = 9e-56
Identities = 373/1729 (21%), Positives = 679/1729 (39%), Gaps = 271/1729 (15%)
Query: 1021 IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL 1080
+W + E I + K + P ++ + L + L ++ + R+L
Sbjct: 1332 VWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASY-EFVQRLL 1390
Query: 1081 GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ 1140
+ L+ +L S + + + L++ L + + + LTLGQ+ L + +
Sbjct: 1391 KGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWV--VSELTLGQIWDVDLQKNEAIVKD 1448
Query: 1141 VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD 1200
V + +E +++++ W +L L+N+ ++K +++R
Sbjct: 1449 VLLVAQGEMALEEFLKQIREVWNTYELDLVNY------------QNKCRLIRG------- 1489
Query: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
+ +L + ++E + +S + + AL W ++ + AL +VW+
Sbjct: 1490 ----------WDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWID 1539
Query: 1261 FQQKWIFLNKVLH---EMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAE 1317
Q++W++L + ++K P RF+ + ++ LM+ P+V+ ++
Sbjct: 1540 VQRRWVYLEGIFTGSADIKHLLPVE--TQRFQSISTEFLALMKKVSKSPLVMDVL----- 1592
Query: 1318 RSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLES 1377
Q +Q+ L+ + L I +L L + FPR +F+ D +L+ ++
Sbjct: 1593 -----NIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNV 1647
Query: 1378 CEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGP 1437
+ Q ++ F V ++ E N+ L + GEEV + P
Sbjct: 1648 AKLQKHFKKMFAGVSSIILN-----EDNS-------------VVLGISSREGEEVMFKTP 1689
Query: 1438 LPL--HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLY 1495
+ + HP + +WL +EK +R+ L +L V ++ K + Y
Sbjct: 1690 VSITEHPKINEWLTLVEKEMRVTLAKLLAESVTE-----------VEIFGKATSIDPNTY 1738
Query: 1496 VQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWG---TLAMVSMHMRKLEVLVNFMRA 1552
+ WID QA Q V+++ ++ W +E AL G A + + +EV +N +
Sbjct: 1739 IT-WIDKYQA---QLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVL-- 1792
Query: 1553 QRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSP 1612
A P +R+ L L+ V RD+ + L + ++ + F W+ Q++++
Sbjct: 1793 --ADSVLMEQPPLRRRKL-EHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFD-- 1847
Query: 1613 HIIPKSP--LQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPA 1670
PK LQ L I + F Y +EYLG + + + L +R
Sbjct: 1848 ---PKQTDVLQQLS---------------IQMANAKFNYGFEYLGVQDKLVQTPLTDRCY 1889
Query: 1671 LVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGAL 1730
L + ALE G+ GP G GK V +L LGR +++ C + Q + G
Sbjct: 1890 LTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLC 1949
Query: 1731 QGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRN-TSTIDPTQPQLLGSSF 1789
Q GAW ++ ++L +LSA+ Q ++ + L + ++ N T P +LL
Sbjct: 1950 QVGAWGCFDEFNRLEERMLSAVSQ---QVQCIQEALREHSNPNYDKTSAPITCELLNKQV 2006
Query: 1790 FEKHHVSVRL----GYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGM 1845
+++ + GY A S +P NL L R +A+ PD + +A++ L G
Sbjct: 2007 KVSPDMAIFITMNPGY-------AGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGF 2059
Query: 1846 RDAFQMATRLSKFFSLERELVSGP--LPCRLPLLKQIL-------EDTIRTLNVTKEE-- 1894
R A +A ++ FF L E +S L LK +L + I+ + KEE
Sbjct: 2060 RTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERG 2119
Query: 1895 --------------------PKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNLRGLLCA 1934
C+ E+ LL S L + G+ H RG + A
Sbjct: 2120 EAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYH--RGEMTA 2177
Query: 1935 LFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPA 1994
L +V E L + ++VG +L QL Q G++++GP+
Sbjct: 2178 LREELKKVCQEMY-------LTYGDGEEVGGMWVEKVL----QLYQITQINHGLMMVGPS 2226
Query: 1995 GSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLY-PSGLSPQEFLGWLEGSC--WH 2051
GSGK+ W L K RL +E + H+ P +S G L+ + W
Sbjct: 2227 GSGKSMAWRVLLKALERLEGVEG----------VAHIIDPKAISKDHLYGTLDPNTREWT 2276
Query: 2052 HGIFPKVLR-AAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSL 2110
G+F VLR QKRQ WI+ DG + W++++ +L + L+L
Sbjct: 2277 DGLFTHVLRKIIDSVRGELQKRQ---------WIVFDGDVDPEWVENLNSVLDDNKLLTL 2327
Query: 2111 PSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRL 2170
P+G++++ PP ++ EV D + V C +VW + +LS M + RL
Sbjct: 2328 PNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSED-----VLSTDMIFNNFLARL 2382
Query: 2171 QHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDL 2230
+ + E A+ + S +LQ+ Q+ + + ++ L+
Sbjct: 2383 RSIPLDEGEDEAQRRRKGK-EDEGEEAASPMLQI--QRDAATIMQPYFTSNGLVTKALEH 2439
Query: 2231 HLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSD--DVPDKCREHLLAVSSFL 2288
+L+ DL+ + F + N +Q +++ D P + + + +L
Sbjct: 2440 AFQLEHIM-----DLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYL 2494
Query: 2289 -FALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEP-PPSALVFDLHVSPEDGTLVPFT 2346
+A++W + +IR R++ P P P+ + D VS G P+
Sbjct: 2495 VYAILWSLSGDSRLKMRAELGEYIR----RITTVPLPTAPNIPIIDYEVS-ISGEWSPWQ 2549
Query: 2347 GQY----LSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGK--SAFVEV 2400
+ + +H P++ T R ++ L+ +P++L G +GK + F +
Sbjct: 2550 AKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSAL 2609
Query: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQP-----GHHQDSKPSLLFLLE 2455
P + FSS+ LL + + P Q K +LF +
Sbjct: 2610 RALPD----MEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLF-CD 2664
Query: 2456 DLHLATSDPEKSCQPVLETLRQAMD-GTVYAHST---LELQTLQPTVNFLATVTVPGYCE 2511
+++L D + Q V+ +RQ ++ G Y S ++L+ +Q V T PG
Sbjct: 2665 EINLPDMD-KYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQ-FVGACNPPTDPG--R 2720
Query: 2512 RPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAW 2571
+PL R R V+ ++ A+L + + +A L PS+ R A L A VE +
Sbjct: 2721 KPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSL---RTYAEPLTAAMVEFY 2777
Query: 2572 EAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRG 2631
F PHY +S ++ + RG E LR + L
Sbjct: 2778 TMSQERF-TQDTQPHYIYSPREMTRWV------------RGIF------EALRPLETL-- 2816
Query: 2632 TCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
++R+W HEA R F DRL ER + + + VA F
Sbjct: 2817 -------PVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHF 2858
Score = 95.5 bits (236), Expect = 1e-18
Identities = 163/761 (21%), Positives = 294/761 (38%), Gaps = 123/761 (16%)
Query: 2857 KLSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLAS-----SICQAH 2911
+L L + + HV R+ R+ +P+ H LLL G G G+ T + S+ Q
Sbjct: 2904 ELDVPLVLFNEVLDHVLRIDRIFRQPQGH-LLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962
Query: 2912 FFHLPSGSEEAILQCLRDASWHAGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQ 2969
+G E + LR +G ++ +A ++ +D L R+ L +G PG
Sbjct: 2963 VHRKYTG--EDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGL 3020
Query: 2970 YTEAD-----LDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIG-DKQAHK 3023
+ E D + + E +E L + + E + + F QV +LH+ F + + K
Sbjct: 3021 F-EGDEYATLMTQCKEGAQKEGLMLDSH---EELYKWFTSQVIRNLHVVFTMNPSSEGLK 3076
Query: 3024 QLPST---LFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQA 3080
+T LF R + ++ + W AL +V + E + L+ ++ PD
Sbjct: 3077 DRAATSPALFNRCV------LNWFGDWSTEALYQVGK---EFTSKMDLEKPNYIVPDYMP 3127
Query: 3081 ----SIPSVAKAMALIHLSATHYHEHLCPA----------LPLVTPKTFLDFLDTFLML- 3125
+P I S H+ L A +TP+ +LDF++ + L
Sbjct: 3128 VVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLF 3187
Query: 3126 --------QQQTIL-----KIKNKAQRVQNALENLRMLIKEHGTHANLIFD-LEQQLKDS 3171
+QQ L KIK +V+ +LR+ +E D L++ +KD
Sbjct: 3188 HEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKD- 3246
Query: 3172 GKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAFLEP 3231
QQ+ E+ K++ ++ E+ Q+ +I + Q + L+++ A +E
Sbjct: 3247 -------QQEAEKKKVMSQEIQEQLHKQQEVIADK-------QMSVKEDLDKVEPAVIEA 3292
Query: 3232 ---LSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHET-GWASAKQLLCTEDFYQELV 3287
+ ++ E+RS PP +V +++C L T W + ++ E+F +V
Sbjct: 3293 QNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIV 3352
Query: 3288 FFPKEKITDSELIKLHL-ILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPT 3346
F E+I+D+ K+ + P + + S + W A L+Y R P
Sbjct: 3353 NFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPL 3412
Query: 3347 DLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAK-----MVEDAQASHNCVAKTLSQ 3401
LQ++E Q + + Q LE ++A K ++ +AQA + L+
Sbjct: 3413 RNELQKLEDDAKDNQQKANEVE-QMIRDLEASIARYKEEYAVLISEAQA----IKADLAA 3467
Query: 3402 AQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQE 3461
+ + +L W + K + T+ GD LL +A I Y G F RQ
Sbjct: 3468 VEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQN 3527
Query: 3462 LLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQY 3521
L W + +I + + T LS+ E+
Sbjct: 3528 LFTTW--------------------SHHLQQANIQFRTDIART-------EYLSNADERL 3560
Query: 3522 QWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEA 3562
+W + P ++L+ R+PL++DPS +A
Sbjct: 3561 RWQASSLPADDLCTENAIMLKRFN-----RYPLIIDPSGQA 3596
Score = 40.0 bits (92), Expect = 0.055
Identities = 124/598 (20%), Positives = 213/598 (35%), Gaps = 82/598 (13%)
Query: 3993 LELLPPFVGLCASLAGHSS--AWQAYLSLSSTV--LGPAPGPGPEPLSLLQKLILWRVLR 4048
L LP F L A + W S TV L P + +L+L + R
Sbjct: 3938 LSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFR 3997
Query: 4049 PECLAGALADFTTSLLGRPLDENTYAPTMPFKHSQATQPM----LILLPPPGHPSATLHP 4104
P+ L F ++ LG P + H T+ +++ PG+ A+ H
Sbjct: 3998 PDRLLAMAHMFVSTNLGESFMSIMEQP-LDLTHIVGTEVKPNTPVLMCSVPGY-DASGH- 4054
Query: 4105 LTVIQKLAAKYQQGQKQLQVIALGS-EAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHW 4163
++ LAA+ Q+ IA+GS E ++ ++T A+ G W++L N HL P W
Sbjct: 4055 ---VEDLAAEQNT---QITSIAIGSAEGFNQADKAINT---AVKSGRWVMLKNVHLAPGW 4105
Query: 4164 PKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPA-V 4222
+L + L L QP H FRL+L + E + +P +
Sbjct: 4106 LMQLEKKLHSL-----------------QP--------HACFRLFLTM--EINPKVPVNL 4138
Query: 4223 LTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLL---HGLLLHRQLYGT 4279
L + VF ++L + + P +A LL H ++ R Y
Sbjct: 4139 LRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAP 4198
Query: 4280 RLQAHRGRWSQVTLTQVLQTQDQLWASLSN----------PRAAMQELAASVFYGGPLGD 4329
+ + + + L T D + P +A++ L A YGG + +
Sbjct: 4199 LGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDN 4258
Query: 4330 TEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAM--AECKAQMHLLP 4387
D+ L + + + S + L + +++ D + E + LLP
Sbjct: 4259 EFDQRLLNTFLERLFTTRSFD-----SEFKLACKVDGHKDIQMPDGIRREEFVQWVELLP 4313
Query: 4388 SPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVN 4447
P GL + LL Q ++S + + + E AE + R +
Sbjct: 4314 DTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQML---EDEDDLAYAETEKKTRTDSTS 4370
Query: 4448 -------RRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQ 4500
R L + H+I Q S +V N + PL E E ++L+ ++
Sbjct: 4371 DGRPAWMRTLHTTASNWLHLIPQTLSHLKRTV--ENIKDPLFRFFEREVKMGAKLLQDVR 4428
Query: 4501 RDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRR 4558
+DL ++Q +G + + + L G LP W + W+ S R
Sbjct: 4429 QDLADVVQVCEGKKK-QTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSER 4485
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 214 bits (545), Expect = 2e-54
Identities = 254/1199 (21%), Positives = 475/1199 (39%), Gaps = 182/1199 (15%)
Query: 969 STEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWHLYRVI 1028
S H++ + R+ + + D +L Y E LPI + + + + Y +
Sbjct: 970 SRAHEIANEVRRVKKQLKDCQQLAMLY---NNRERIFSLPITNYDKLSRMVKEFQPYLDL 1026
Query: 1029 SENISEWKCMAFAKFSP---AMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRI------ 1079
S+W + + + A+ E+ E + EA + + C +
Sbjct: 1027 WTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRA 1086
Query: 1080 -LGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRI 1138
+ EF+ Y+PL+ L + + + + L + + +++ LT + L L + + I
Sbjct: 1087 RIEEFKPYIPLIQGLRNPGMRIRHWETLSNQINI-NVRPKANLTFARCLEMNLQDHIESI 1145
Query: 1139 NQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEV 1198
++V + + ++ + ++++ W +L PY+ + +L+SP
Sbjct: 1146 SKVAEVAGKEYAIEQALDKMEKEWSTILFNVL------PYKA-----TDTYILKSP---- 1190
Query: 1199 VDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVW 1258
D + +L D+ + ++ S K + NK+ L +LE W
Sbjct: 1191 ---DEASQLLDDHIVMTQNM--SFSPYKKPFEQRINSWENKLKLTQ--------EVLEEW 1237
Query: 1259 LTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAER 1318
L Q+ W++L + F + D+N + V +Y+T+ RI ++ + E
Sbjct: 1238 LNCQRSWLYLEPI-------FSSEDINQQLPVESKRYQTMERIW---KKIMKNAYENREV 1287
Query: 1319 SPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESC 1378
++ L+ + L+ + L L + FPR +FLSD EL+ +L+ +
Sbjct: 1288 INVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPT 1347
Query: 1379 EAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPL 1438
Q +R+CF ++ + F Q +E + A GEEV+L +
Sbjct: 1348 AVQPHLRKCFENIARLLF-------------------QEDLEITHMYSAEGEEVQLCFSI 1388
Query: 1439 PLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQH 1498
++ WL +E+ ++ ++ +++ + A +P+ +V +
Sbjct: 1389 YPSSNVEDWLREVERSMKASVHDIIEKAI-----------RAYPTMPRTQ------WVLN 1431
Query: 1499 WIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLA--MVSMHMRKLEVLVNFMRAQRAS 1556
W P Q + + W E+ EAL E G L + ++L LV +R + +
Sbjct: 1432 W-------PGQVTIAGCQTYWTMEVAEAL-EAGNLRSQLFPQLCQQLSDLVALVRGKLSR 1483
Query: 1557 QGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIP 1616
Q ++LSAL+V+ V +D+ L Q V + DF W+ QL+Y+ + +
Sbjct: 1484 M---------QRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDL-- 1532
Query: 1617 KSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLA 1676
+I + F+Y YEYLG + + L +R L L A
Sbjct: 1533 ----------------------YIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGA 1570
Query: 1677 LEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWL 1736
L G GP G GK L +AL Q V+ CS Q++ + + G GAW
Sbjct: 1571 LHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWA 1630
Query: 1737 LLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVS 1796
++ +++ +LS + Q++ +TI Q Q + FE V
Sbjct: 1631 CFDEFNRIDIEVLSVVAQQI------------------TTIQKAQQQRVERFMFE--GVE 1670
Query: 1797 VRLGYGCLLVLR-----ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQM 1851
+ L C + + A + +P NL L RPVA+ +PD + E++L G +A +
Sbjct: 1671 IPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVL 1730
Query: 1852 ATRLSKFFSLERELVSGP--LPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEA 1909
A +++ F L E +S + +K ++ N+ +E P + L +
Sbjct: 1731 AKKITTTFKLSSEQLSSQDHYDFGMRAVKTVIS---AAGNLKRENPSMNE--ELICLRAI 1785
Query: 1910 ALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSP 1969
+ P F + L L + G++ LFP+ + E Y ++ + E + L
Sbjct: 1786 RDVNVPKF-LQEDLKLFS--GIVSDLFPTIKE---EDTDYGILDEAIREACRNSNLKDVE 1839
Query: 1970 DILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEIT 2029
L QL + G++L+GP GSGK+TC+ L L S + V
Sbjct: 1840 GFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYY 1899
Query: 2030 HLYPSGLSPQEFLGWLE--GSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087
L P ++ + G + W GIF +RA ++ +K W + D
Sbjct: 1900 VLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKK-----------WYMFD 1948
Query: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVW 2146
G + W++++ +L + +L L SG+ I ++ EV D SP V C +V+
Sbjct: 1949 GPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVY 2007
Score = 154 bits (388), Expect = 3e-36
Identities = 240/1124 (21%), Positives = 422/1124 (37%), Gaps = 161/1124 (14%)
Query: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPPQVQPG---- 3719
L V +D + ++ A G P LL NV EEL L+ L Q G
Sbjct: 3253 LDVFKLSDRDFLRSMENAIRFGKPCLLENVG-----EELDPALEPVLLKQTYKQQGNTVL 3307
Query: 3720 ------------FCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILC 3767
F +Y++T L E+ L +++ L+ LE+Q+L +++
Sbjct: 3308 KLGDTVIPYHEDFRMYITTKLP----NPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVA 3363
Query: 3768 REYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLC 3827
E P+LE L I + ++ E+++L L + ++ + ++ K
Sbjct: 3364 EERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAA 3423
Query: 3828 QLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQ 3887
+++A E + + Y PV + +S L N+ P++ S E +L +
Sbjct: 3424 EIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLS 3483
Query: 3888 ALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATG 3947
+ + + ++L + + +LT L + +L + L + ++ G
Sbjct: 3484 GIANSE-----RADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEG 3538
Query: 3948 KASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLA 4007
K ++ E L G S S + P D WL +AW + L LP F +
Sbjct: 3539 KINQSEWRYLLSG--GSISIMTENPAPD-----WLSDRAWRDILALSNLPTFSSFSSDFV 3591
Query: 4008 GHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADF-TTSLLGR 4066
H S ++ P PG + L QKL++ R LR + + A+ DF T+L R
Sbjct: 3592 KHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPR 3651
Query: 4067 PLDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIA 4126
++ T ++ FK S +T P++ +L P P+A L+ A+ + K+L I+
Sbjct: 3652 FIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKF-------AEEMKFSKKLSAIS 3704
Query: 4127 LGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLES 4186
LG + + ++ G W+ NCHL P W L +L+
Sbjct: 3705 LGQGQGPRAEAM---MRSSIERGKWVFFQNCHLAPSWMPALERLI--------------- 3746
Query: 4187 EQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSV 4246
E N VHRDFRLWL + S P + Q+ + + L+ S
Sbjct: 3747 -------EHINPDKVHRDFRLWL--TSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSY 3797
Query: 4247 -ELAQQVL-----YMQPPTQALPLLLLHGLLLHRQLYGT-------RLQAHRGRWSQVTL 4293
L + L M+ + L L L HG L R+ +G R L
Sbjct: 3798 SSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQL 3857
Query: 4294 TQVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQ 4353
L D + P ++ A + YGG + D DR ++++ + +P S
Sbjct: 3858 KMFLDEYDDI------PYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEH 3911
Query: 4354 PHTPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRAL 4413
++ + + P +L + + LP P + GL + + ++ AL
Sbjct: 3912 SYSASGIYHQIPPTYDLHGY------LSYIKSLPLNDMPEIFGLHDNANITFAQNETFAL 3965
Query: 4414 LSALQRSSPVWVPESRRG-AQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSV 4472
L + + P +G ++ E + L++V + + + + +ES
Sbjct: 3966 LGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEES------ 4019
Query: 4473 LGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGR 4532
+ VL E + ++L+ + + L LL+ LKG S + +A +L+
Sbjct: 4020 --------MNTVLVQEVIRYNRLLQVITQTLQDLLKALKGL-VVMSSQLELMAASLYNNT 4070
Query: 4533 LPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRL 4592
+P W A +P W+ L +R L ++ G A VF +S F P+
Sbjct: 4071 VPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPA-------VFWISGFFFPQAF 4123
Query: 4593 LLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVE-NGPNPTV--PER 4649
L G++ + + + +++ F+V P+ P+
Sbjct: 4124 L---------------------TGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQV 4162
Query: 4650 GLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAP----ADLTVY 4705
G + GL + A WDP A L +S P + T+ LP P D Y
Sbjct: 4163 GCYIHGLFLEGARWDPEAFQLAES--------QPKELYTEMAVIWLLPTPNRKAQDQDFY 4214
Query: 4706 SCPVY----MGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
CP+Y G L T S N V+ + +PT ++R V
Sbjct: 4215 LCPIYKTLTRAGTLSTTG-HSTNYVIAVEIPTHQPQRHWIKRGV 4257
Score = 94.4 bits (233), Expect = 2e-18
Identities = 140/670 (20%), Positives = 252/670 (37%), Gaps = 72/670 (10%)
Query: 2843 EKLEEQLATSAAQLKLSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAIT 2902
E +E+ + A+LKL + H+ R+ R L + + LLL G G+GR +
Sbjct: 2543 EYIEDYNQINTAKLKLVLFM----DAMSHICRISRTLRQALGNALLL-GVGGSGRSSLTR 2597
Query: 2903 LASSICQAHFFHLPSGSEEAILQCLRDAS---WHAGMLSQPVALLVPSGV--DLTTLHRL 2957
LAS + + F + + + D AG+ + P+ L + + L +
Sbjct: 2598 LASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDI 2657
Query: 2958 LALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFL-- 3015
+ SG P YT + D+I + K ++ + +V S++H+
Sbjct: 2658 NNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMS 2717
Query: 3016 -IGD--KQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGS 3072
IG+ + +Q PS + +ID + W AL VA L
Sbjct: 2718 PIGEVFRARLRQFPSLV-------NCCTIDWFNEWPAEALKSVATVFLN----------- 2759
Query: 3073 WKYPDLQAS---IPSVAKAMALIHLSATHYHEHLCPALP---LVTPKTFLDFLDTFLMLQ 3126
+ P+L++S I + + IH S + L VTPK++L+ L F +L
Sbjct: 2760 -EIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILI 2818
Query: 3127 QQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSK 3186
Q L++K R+++ L+ L ++ + + L+++ K + +Q++
Sbjct: 2819 GQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDT 2878
Query: 3187 LLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAF---LEPLSQLQVADFEEI 3243
+ ++ + +E A++ A+ + L++ A L L L D E+
Sbjct: 2879 AIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEV 2938
Query: 3244 RSYRAPPESVVRVTDAMCDL--------------FHHETGWASAKQLLCTEDFYQELVF- 3288
R+ + PP V V +A+C + + W K LL + E +F
Sbjct: 2939 RAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFK 2998
Query: 3289 FPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDL 3348
F K+ I D + + + A + VS+ S+ W+ A+ Y
Sbjct: 2999 FDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVA-------K 3051
Query: 3349 LLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQASHN-CVAKT----LSQAQ 3403
++ L Q LG Q E + + + QA + C+ K L Q
Sbjct: 3052 AVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQ 3111
Query: 3404 CGQY--HKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQE 3461
C Q + L W ++ L+ + GD L+ + + YLGPF R
Sbjct: 3112 CEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTV 3171
Query: 3462 LLDEWLALCR 3471
L D W+ R
Sbjct: 3172 LYDSWVKQLR 3181
Score = 77.4 bits (189), Expect = 3e-13
Identities = 96/427 (22%), Positives = 163/427 (38%), Gaps = 81/427 (18%)
Query: 2287 FLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSP--------- 2337
F+F+LIW GA S F ++R + P LVFD +
Sbjct: 2107 FIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDS 2166
Query: 2338 ----EDGTLVPFTGQYLSSHIKGTL-------GTFHPSIQTERLLYVVDLLLSGGQPVLL 2386
E+ V + +++ S T+ P++ T ++ +++D+LL+ +PVL
Sbjct: 2167 EDEEEEYKQVAWV-KWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLC 2225
Query: 2387 AGEAATGKSAFV--EVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQ 2444
G TGK+ + ++L YI SH +R QTQ +
Sbjct: 2226 IGPTGTGKTLTISDKLLKNLALDYI----------SHFLTFSARTSANQTQDFIDSKLDK 2275
Query: 2445 DSKP--------SLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQ 2495
K + +F ++DL++ + QP +E LRQ MD G Y +
Sbjct: 2276 RRKGVFGPPLGRNFIFFIDDLNMPALETY-GAQPPIELLRQWMDHGGWYDRKIIGAFKNL 2334
Query: 2496 PTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWL-------- 2547
+NF+ + PG + PRL R F L+ M + + I+ WL
Sbjct: 2335 VDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKS 2394
Query: 2548 --ERFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLP 2605
ER P LV A++ + + + +P+P HY F+L +S + + +
Sbjct: 2395 YRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLM-- 2452
Query: 2606 NRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRER 2665
D ++ ++ ++RLW HE R F DRL + +R
Sbjct: 2453 --------ADPAKVEDQVQ------------------LLRLWYHENCRVFRDRLVNEEDR 2486
Query: 2666 SYCAKLL 2672
S+ +LL
Sbjct: 2487 SWFDQLL 2493
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 204 bits (518), Expect = 2e-51
Identities = 252/1199 (21%), Positives = 478/1199 (39%), Gaps = 178/1199 (14%)
Query: 988 LSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAM 1047
+ + HH F +E L ++ I +IW Y + E + F
Sbjct: 1101 VDDCHH----FRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITF---- 1152
Query: 1048 AQEKTEGWLTEAARMS-----TTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSLN 1102
+T+ +L E M+ +E HS + + +++ +P+L + H +
Sbjct: 1153 ---RTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDH 1209
Query: 1103 CQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYW 1162
L R LGL ++E L G LL A + ++ N R + TIR R
Sbjct: 1210 WLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADL--KDLNSRAQGEVTIREALREL 1267
Query: 1163 EARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESL 1222
+ + + F L + YE S K ++ D+ ++ + + ++
Sbjct: 1268 DLWGVGAV-FTL-IDYEDSQSRTMK-------------------LIKDWKDIVNQVGDNR 1306
Query: 1223 QVLSKIL-AIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVLHEMKIQFPN 1281
+L + + G +K+++ W + L L+ Q+KW++L + +
Sbjct: 1307 CLLQSLKDSPYYKGFEDKVSI-WERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQ 1365
Query: 1282 ADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGI 1341
+RF +D+ +R++M D V +L + R+ L +L +L+
Sbjct: 1366 ----TRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRN------SLLTILD----QLQRC 1411
Query: 1342 IMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFRSCPT 1401
SL L + FPR +F+ D +L+ +L Q +++ F +++V F
Sbjct: 1412 QKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF----- 1466
Query: 1402 GEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVH 1461
D +S T A+ GE V + +PL ++ WL L ++ L
Sbjct: 1467 ------DEKSKHIT-------AMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQ 1513
Query: 1462 MLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEVVWRA 1521
+L+ CV + ++ +L FP Q + +AE++ +
Sbjct: 1514 LLKECVTTGRSSQGAVDPSL------------------------FPSQILCLAEQIKFTE 1549
Query: 1522 EMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTH 1581
++E A+ + + + + KLE N +S+ + S L AL++ + +
Sbjct: 1550 DVENAIKDHSLHQIETQLVNKLEQYTNI---DTSSEDPGNTESGILELKLKALILDIIHN 1606
Query: 1582 RDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWID 1641
D+ + L Q QV D+ W +QL++++ S H C +
Sbjct: 1607 IDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDH-----------------------TCCVQ 1643
Query: 1642 VLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLA 1701
++ F Y YEY G + + L ++ L L A++ G GP G GK V +L
Sbjct: 1644 MVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALG 1703
Query: 1702 QALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHH 1761
LGRQ+++ C I+ + + G ++ GAW ++ ++L +LSA+ ++ +
Sbjct: 1704 GLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTI-- 1761
Query: 1762 LYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSA------VP 1815
Q+A +N T+ +LLG V V G + + +P
Sbjct: 1762 ------QDALKNHRTV----CELLGK------EVEVNSNSGIFITMNPAGKGYGGRQKLP 1805
Query: 1816 ANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGP--LPCR 1873
NL L RPVA++ PD +AE+ L G +DA ++ +L F+L REL++
Sbjct: 1806 DNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWG 1865
Query: 1874 LPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNLRGLLC 1933
L LK +L + L + Q + +A LR S L+
Sbjct: 1866 LRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQA--LRLNTMSKFTFTDCTRFDALIK 1923
Query: 1934 ALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGP 1993
+FP + + + Y + + + ++ + P+ + +L + L + G++++GP
Sbjct: 1924 DVFPG---IELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGP 1980
Query: 1994 AGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WH 2051
+G+GK+T W L AA+ T + V+ + P + + LG ++ W
Sbjct: 1981 SGAGKSTLWRML------RAALCKTG----KVVKQYTMNPKAMPRYQLLGHIDMDTREWS 2030
Query: 2052 HGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLP 2111
G+ R + E + WIICDG + W++S+ +L + L++P
Sbjct: 2031 DGVLTNSAR-----------QVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMP 2079
Query: 2112 SGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQT-WQCILSALMASLPYEYR 2169
SG++I P + E D + SP + +++ E+T ++ + + + P EYR
Sbjct: 2080 SGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYR 2138
Score = 90.1 bits (222), Expect = 5e-17
Identities = 158/728 (21%), Positives = 287/728 (39%), Gaps = 87/728 (11%)
Query: 2866 HSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQ 2925
H + ++++R+ RVL+ P LLL+G G GR T +L S + A F P S L+
Sbjct: 2631 HEVLEYMSRIDRVLSFPGG-SLLLAGRSGVGRRTITSLVSHMHGAVLFS-PKISRGYELK 2688
Query: 2926 CLRDASWH----AGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQYTEADLDRIG 2979
++ H AG+ +Q V LL+ V T L + +L +SG PG YT +L+ +
Sbjct: 2689 QFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPL- 2747
Query: 2980 EHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATA 3039
LP ++ + V F ++ +LH+ ++ ++ + L +
Sbjct: 2748 -LLPLKDQASQDGFFGP-VFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHK--KC 2803
Query: 3040 SIDRYEPWDQAALAKVAQHHL-EGAQSVPLDDGSWKYPDLQASI-PSVAKAMALIHLSAT 3097
+ E W +++ K+ + E +D K + S+ P K+ LIH S
Sbjct: 2804 QVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCK 2863
Query: 3098 HYHEHLCPALPLVTPKTFLDFLDTFLML---QQQTILKIKNKAQRVQNALENLRMLIKEH 3154
Y TP ++ FL + + +++ +LK ++ Q + L + L+ E
Sbjct: 2864 AYG---------ATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDEL 2914
Query: 3155 GTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQ--ENLIENLARQRDA 3212
A L + +D + Q K +LE +H+ E +++ + +++
Sbjct: 2915 NRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVK-IEERKNK 2973
Query: 3213 LQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFH-HETGWA 3271
+ + + +++A L + ++ EIRS R PP+ + + + + L +T W
Sbjct: 2974 IDDELKEVQPLVNEAKLA-VGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWV 3032
Query: 3272 SAKQLLCTEDFYQELVFFPKEKITDS--ELIKLHLILKAPGMDDAALRAVSRPAASLAAW 3329
S K L +++ F I+ E ++ L D + S AA LAAW
Sbjct: 3033 SMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAW 3092
Query: 3330 LWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEH-NLALAKMVEDA 3388
+ A + Y R P + +E+ L + + R + + +E L ++++ E
Sbjct: 3093 VKANIQYSHVLERIHPLETEQAGLESNLKKTEDR----KRKLEELLNSVGQKVSELKEKF 3148
Query: 3389 QASHNCVAKTLSQAQCGQYHKWPMKAA------LLTPMRAWTTQLQKLKGRCMTVFGDTL 3442
Q+ + AK ++ Q +KAA L + W Q+ ++ T+
Sbjct: 3149 QSRTSEAAKLEAEVSKAQE---TIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQ 3205
Query: 3443 LCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLL 3502
L +A I YL P R+ L+EW KS +
Sbjct: 3206 LAAAFITYLSAAPESLRKTCLEEW-----------------------TKSAGL------- 3235
Query: 3503 ATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRW----PLLLDP 3558
F + L +ESEQ W P + L++ S W P L+DP
Sbjct: 3236 ---EKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKS--WSRVCPFLIDP 3290
Query: 3559 SNEALIWL 3566
S++A WL
Sbjct: 3291 SSQATEWL 3298
Score = 73.2 bits (178), Expect = 6e-12
Identities = 144/651 (22%), Positives = 248/651 (38%), Gaps = 77/651 (11%)
Query: 3979 PAWLGP-KAWHECEMLELLPP-FVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLS 4036
P+W+ ++W + LP + LC A + W+ Y + +S P + +S
Sbjct: 3622 PSWIDQERSWAVATLKIALPSLYQTLCFEDA---ALWRTYYN-NSMCEQEFPSILAKKVS 3677
Query: 4037 LLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPT---MPFKHSQATQPMLILLP 4093
L Q++++ + LRP+ L A+A F LG L E + P +K + +P+LI++
Sbjct: 3678 LFQQILVVQALRPDRLQSAMALFACKTLG--LKEVSPLPLNLKRLYKETLEIEPILIIIS 3735
Query: 4094 PPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLV 4153
P PS L L ++ Y Q +A+G D + + L + G WL
Sbjct: 3736 PGADPSQELQELANAERSGECYHQ-------VAMGQGQAD---LAIQMLKECARNGDWLC 3785
Query: 4154 LDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPA 4213
L N HL+ W + LE E QP+ FRLWL A
Sbjct: 3786 LKNLHLVVSW-----------------LPVLEKELNTLQPKD--------TFRLWL--TA 3818
Query: 4214 ESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVE--LAQQVLYMQPPTQALPLLLL---H 4268
E + +L Q S+ + + L L+ + E +Q+ +A L L H
Sbjct: 3819 EVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFH 3878
Query: 4269 GLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPR-AAMQELAASVFYGGPL 4327
R+ Y + +S L D+L+ + + + L + YGG +
Sbjct: 3879 AACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRI 3938
Query: 4328 GDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECKAQMHLLP 4387
+ D L S + + S +S+ + LP + ++ + +A + +P
Sbjct: 3939 DNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLP---QSCSILDYRAVIEKIP 3995
Query: 4388 SPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVN 4447
+P GL + R S+ ++S+ S + S +R + +
Sbjct: 3996 EDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPV 4050
Query: 4448 RRLESLQDLLTHVIRQDESDAPWSVLGPNARR--PLEGVLETEALELSQLVGTLQRDLDC 4505
L + +++I Q V PN R+ P+ + E +LV ++ + L
Sbjct: 4051 LNLWKKLNQNSNLIHQ-------KVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAA 4103
Query: 4506 LLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRY 4565
L + ++G S +A AL + PL W+ GP+ P +LR L R + +
Sbjct: 4104 LSKVIRGT-TLLSSEVQKLASALLNQKCPLAWQSKW-EGPEDPLQYLRGLVARALAIQNW 4161
Query: 4566 LGVGADASSDVPERVFHLSAFRHPRRLLLALRGEA--ALDQNVPSSNFPGS 4614
V + LS HP L ALR E A+ ++V S F S
Sbjct: 4162 --VDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVAS 4210
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 197 bits (501), Expect = 2e-49
Identities = 322/1711 (18%), Positives = 653/1711 (38%), Gaps = 255/1711 (14%)
Query: 978 ERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWHLYRVISENISEWKC 1037
ER+ EL +A +F T P + + + + I+ LY + EW
Sbjct: 1224 ERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQ 1283
Query: 1038 MAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLH 1097
+ + + QE EG+L ++ + S V + + F+ +PLL L +
Sbjct: 1284 TLWINLNVQILQEGIEGFLRALRKLPRPVRGLS-VTYYLEAKMKAFKDSIPLLLDLKNEA 1342
Query: 1098 PQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRR 1157
+ + + L+ + + E TL + L + D +N++ + + ++ ++
Sbjct: 1343 LRDRHWKELMEKTSV-FFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKE 1401
Query: 1158 LQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDS 1217
+ WE + + V Y ER +IL + S
Sbjct: 1402 ILDTWENMKFTV------VKYCKGTQERG-------------------YILGSVDEIIQS 1436
Query: 1218 IQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVLHEMKI 1277
+ ++ L I G + +W + +G ++E+W+ Q+KW++L + I
Sbjct: 1437 LDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDI 1496
Query: 1278 QFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVE 1337
+ + +F +D ++ +M ++ DP++ S LQ S
Sbjct: 1497 RSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSD----------LQNVSEG 1546
Query: 1338 LEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397
LE SL L FPR FF+SD EL+++L + C + ++ + ++ ++ F
Sbjct: 1547 LEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKM-YDNIASLRFN 1605
Query: 1398 SCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRL 1457
+GEK A++ A GE ++ + L + W+ ++ +R
Sbjct: 1606 DGDSGEKLVS---------------AMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRR 1650
Query: 1458 ALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEV 1517
+L + ++ + +D + + VL A +V
Sbjct: 1651 T-----------------------NRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQV 1687
Query: 1518 VWRAEMEEAL--LEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLP-SVRQTSLLSAL 1574
W E+E+ + G + + RK+ ++ + + ++P S + +
Sbjct: 1688 WWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRI------TMPLSKNDRKKYNTV 1741
Query: 1575 LVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLS 1634
L++ V RDI + + + +F W QL+++
Sbjct: 1742 LIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDR----------------------E 1779
Query: 1635 PAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKR 1694
P I +F Y YEY+G + + L +R L L AL G GP G GK
Sbjct: 1780 PDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKT 1839
Query: 1695 AIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQ 1754
LA+ALG V+ C ++ + + +G Q GAW ++ +++ +LS +
Sbjct: 1840 ETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISS 1899
Query: 1755 RLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLR---ALS 1811
++ + + A ++Q L + FE +S+ G + + A
Sbjct: 1900 QIQTIRN--ALIHQ----------------LTTFQFEGQEISLDSRMGIFITMNPGYAGR 1941
Query: 1812 SAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLP 1871
+ +P ++ L RPV + +PDL+Q+ E+ L G +A +A +++ + L RE +S
Sbjct: 1942 TELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLS---- 1997
Query: 1872 CRLPLLKQILEDT-IRTLNVTKEEPKCQKPRSLAAIEEAALLRS------PLFSILNGLH 1924
KQ D +R L K S E+ L+R+ P F + +
Sbjct: 1998 ------KQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKF-VFEDVP 2050
Query: 1925 LHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSR 1984
L GL+ LFP + Y V + L++ G P + + Q+ + +
Sbjct: 2051 L--FLGLISDLFPGLD---CPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLT 2105
Query: 1985 ASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGW 2044
+++GP GK+ ++L + Q +L ++ L P +S E G
Sbjct: 2106 RHTTMVVGPTRGGKSVVINTLCQAQTKLGLT----------TKLYILNPKAVSVIELYGI 2155
Query: 2045 LEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLL 2102
L+ + W G+ + R + N K++ + +I+ DG + W++++ ++
Sbjct: 2156 LDPTTRDWTDGVLSNIFR---EINKPTDKKERK-------YILFDGDVDALWVENMNSVM 2205
Query: 2103 SELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQ-TWQCILSALM 2161
+ L+L +G++I LL EV D SP V C +V+ + ++ +
Sbjct: 2206 DDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWV 2265
Query: 2162 ASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVC--AGVAEVTS 2219
+P + + LN + E VP + + +G+ Q + + + VT
Sbjct: 2266 NQIPNKVEQYN-----LNSLFEKYVPYLMDVIV-EGIVDGRQAEKLKTIVPQTDLNMVTQ 2319
Query: 2220 MARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVP-DKCR 2278
+A++L +LL+ + EDL D + F + L S ++ + D+
Sbjct: 2320 LAKMLDALLEGEI----------EDL---DLLECYFLEALYCSLGASLLEDGRMKFDEYI 2366
Query: 2279 EHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE 2338
+ L ++S+ +W LP + ++D H +
Sbjct: 2367 KRLASLSTVDTEGVWANPGELPGQL------------------------PTLYDFHFDNK 2402
Query: 2339 DGTLVPFT---GQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKS 2395
VP++ +Y+ + + + ++ T R ++++ ++ QPV+ GE+ T K+
Sbjct: 2403 RNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKT 2462
Query: 2396 AFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLE 2455
A + ++ + FSS + + R ++ + + + LL ++
Sbjct: 2463 ATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMD 2522
Query: 2456 DLHLATSDPEKSCQPVLETLRQAMDGTVYAH-STLELQTLQPTVNFLATVTVPGYCERPL 2514
D+++ D + QP+ G +Y L ++++ + F+A + G +
Sbjct: 2523 DMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIR-DLGFIAAMGKAGGGRNEV 2581
Query: 2515 CPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAV 2574
PR LF+V + ++ +L + I++ F E A++ L ++ ++ +
Sbjct: 2582 DPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFH--ESIVAVSGKLTFCTLALYKNI 2639
Query: 2575 CNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCL 2634
P+P HY F+L +S + + L L + E + V+
Sbjct: 2640 VQDLPPTPSKFHYIFNLRDLSRVFNGLVL--------------TNPERFQTVA------- 2678
Query: 2635 TVMMATRNVVRLWLHEAQRTFCDRLDSPRER 2665
+VR+W +E R F DRL S ++
Sbjct: 2679 -------QMVRVWRNECLRVFHDRLISETDK 2702
Score = 121 bits (303), Expect = 2e-26
Identities = 162/725 (22%), Positives = 302/725 (41%), Gaps = 89/725 (12%)
Query: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLAS--SICQAHFFHLPSG-SEEAILQC 2926
+H+ R+ R++ R H LL+ G G+G+ + LA+ + C+ L G SE + +
Sbjct: 2783 EHLTRVHRIIRMDRGHALLV-GVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFRED 2841
Query: 2927 LRDASWHAGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPR 2984
L+ G+ ++ + L + L + + TSG P ++E + + I + +
Sbjct: 2842 LKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQ 2901
Query: 2985 ENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRY 3044
E L KE V Q F + ++LH+ ++G L + + ID +
Sbjct: 2902 EALKQGMGPAKESVWQYFVNKSANNLHI--VLGMSPVGDTLRTWCRNFPGMVNNTGIDWF 2959
Query: 3045 EPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLC 3104
PW AL VA+ L +P ++ I +V K + L+H S HY +
Sbjct: 2960 MPWPPQALHAVAKSFLGYNPMIPAEN-----------IENVVKHVVLVHQSVDHYSQQFL 3008
Query: 3105 PALP---LVTPKTFLDFLDTFL-MLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANL 3160
L VTPK +LDF++T+ +L ++T I + +R+ L+ L+ +
Sbjct: 3009 QKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIA-QCKRLDGGLDKLKEATIQLDELNQK 3067
Query: 3161 IFDLEQQLKDSGKSLSMFQQQL-------EQSKLLYKQQLEECRHQENLIENLARQRDAL 3213
+ + + L + + +++ E+ K L +++ E Q +I + +
Sbjct: 3068 LAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETT 3127
Query: 3214 QAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLF-HHETGWAS 3272
A+ LE A LE L +L +D EIRS+ PP+ V V + + + + E W +
Sbjct: 3128 LAEVMPILEA---AKLE-LQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKT 3183
Query: 3273 AKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWA 3332
AK ++ +F + L+ + IT S++ + +LK + AVS+ + ++ A
Sbjct: 3184 AKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEA 3243
Query: 3333 VLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNL-ALAKMVEDAQAS 3391
V+ Y P + ++E R Y + E +++ L A+ K +E A
Sbjct: 3244 VMGYCDVFREIKPKREKVARLE--------RNFYLTKRELERIQNELAAIQKELETLGAK 3295
Query: 3392 HNCVAKTLSQAQCGQYHKWPMKAALLTPMR----------AWTTQLQKLKGRCMTVFGDT 3441
+ + + Q Q M+ L+ + W L +L R + + GD
Sbjct: 3296 YEA---AILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDC 3352
Query: 3442 LLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPL 3501
LLC+A + Y G F R E+++ + +D+ L+R+
Sbjct: 3353 LLCAAFLSYEGAFTWEFRDEMVNR-----------IWQNDI---LERE------------ 3386
Query: 3502 LATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNE 3561
+ PF + SLL+ + E +W P + + G+L + R+PL +DP +
Sbjct: 3387 IPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTT-----RASRFPLCIDPQQQ 3441
Query: 3562 ALIWL 3566
AL W+
Sbjct: 3442 ALNWI 3446
Score = 102 bits (254), Expect = 9e-21
Identities = 201/926 (21%), Positives = 340/926 (36%), Gaps = 104/926 (11%)
Query: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLG------CEELQWLLQREQ---LSPP 3714
L V S DP+ QL+ + G P L +V+ + E+ + Q Q L
Sbjct: 3455 LRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDK 3514
Query: 3715 QVQ--PGFCLYLSTTLSLCAME-KVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYP 3771
+V F LYL+T L+ V G + V++ + ++ LE+Q+L ++ E
Sbjct: 3515 EVDYDSNFRLYLNTKLANPRYSPSVFGKAM-----VINYTVTLKGLEDQLLSVLVAYERR 3569
Query: 3772 ELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRA 3831
ELE + + L + ++ E+ LL L + + + K ++
Sbjct: 3570 ELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSE 3629
Query: 3832 HCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDS 3891
+ E L L YRP G + LS++ + ++ S +L V + +L
Sbjct: 3630 KLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKK 3689
Query: 3892 MKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASE 3951
P I L L + LT + T L L + + QA G+ +
Sbjct: 3690 SLPDSI-----LMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQ 3744
Query: 3952 LERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELL--PPFVGLCASLAGH 4009
E G + + KP AWL + W + +L + F L + +
Sbjct: 3745 EELDFFLKGNISLEKSKRKKPC------AWLSDQGWEDIILLSEMFSDNFGQLPDDVENN 3798
Query: 4010 SSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLD 4069
+ WQ + L S P P ++ QKL++ R R + + A+ D+ T +G
Sbjct: 3799 QTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMG---- 3854
Query: 4070 ENTYAPTMP-----FKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQV 4124
E P M F+ S P++ +L P P+ T + KLA + G +L+
Sbjct: 3855 EKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPA------TDLMKLAERSGFGGNRLKF 3908
Query: 4125 IALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADL 4184
+A+G V + L A+ G WL+L NCHL+ W K+L + L
Sbjct: 3909 LAMGQ---GQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSL------------- 3952
Query: 4185 ESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWN--QSLELGHVL 4242
++ H DFRLWL + + P + Q S+ V L+L ++
Sbjct: 3953 -----------ERITKPHPDFRLWL--TTDPTKGFPIGILQKSLKVVTEPPNGLKL-NMR 3998
Query: 4243 IDSVELAQQVLYMQPPTQALPLL----LLHGLLLHRQLYGT---RLQAHRGRWSQVTLTQ 4295
+++ ++L P PL+ H ++ R+ +G + +
Sbjct: 3999 ATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCME 4058
Query: 4296 VLQTQDQLWASLSNPR---AAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWV 4352
+L T +PR +++ L V YGG D+ DR L L
Sbjct: 4059 ILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTF 4118
Query: 4353 QPHTPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRA 4412
QP +P E + E + LP P + GL + + +R
Sbjct: 4119 QPFHFFRNKEVDYKIPVGDEKEKFVEA---IEALPLANTPEVFGLHPNAEIGYYTQAARD 4175
Query: 4413 LLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSV 4472
+ + L P ES G + + Q ++ ++ + DL R +P SV
Sbjct: 4176 MWAHLLELQP-QTGESSSGIS-RDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSV 4233
Query: 4473 LGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGR 4532
VL E ++LV + + L L + L G S VA +L+ G
Sbjct: 4234 -----------VLLQELERFNKLVVRMTKSLAELQRALAGEVGM-SNELDDVARSLFIGH 4281
Query: 4533 LPLPWRPHAPAGPQPPWHWLRQLSRR 4558
+P WR AP + +W+ RR
Sbjct: 4282 IPNIWRRLAPDTLKSLGNWMVYFLRR 4307
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 187 bits (474), Expect = 3e-46
Identities = 333/1636 (20%), Positives = 622/1636 (38%), Gaps = 298/1636 (18%)
Query: 1087 LPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNEN 1146
L +T+L S + + L++A+G+ L E TL LL L D + ++
Sbjct: 1399 LRAITELQSPALRDRHWHQLMKAIGVKFLIN-EATTLADLLALRLHRVEDDVRRIVDKAV 1457
Query: 1147 ERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTF 1206
+ + ++ I + + W + F V Y +G
Sbjct: 1458 KELGTEKVITEISQTWAT-----MKFSYEVHYR-----------------------TGIP 1489
Query: 1207 ILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWI 1266
+L L ++++ + L +L + + L W ++ ++ W+ Q+ W
Sbjct: 1490 LLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWS 1549
Query: 1267 FLNKVL---HEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQ 1323
L + +++IQ RF +D +++ LM V +++ + + Y +
Sbjct: 1550 HLESIFVCSEDIRIQLVKDA--RRFDGVDAEFKELM---FKTAKVENVLEATCRPNLYEK 1604
Query: 1324 GQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLW 1383
+ LQ L L + + FPR +F+S ++L+ +L+ + +
Sbjct: 1605 LKDLQSRLSLCEKALAEYLETKRIA-------FPRFYFVSSADLLDILSKGAQPKQVTCH 1657
Query: 1384 VRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPD 1443
+ + F + + F E N D + A+ + E V Q
Sbjct: 1658 LAKLFDSIADLQF------EDNQD--------VSAHRAVGMYSKEKEYVPFQAECECVGH 1703
Query: 1444 LPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLV 1503
+ WL LE+ ++ + H + + A ++ P++ ++
Sbjct: 1704 VETWLLQLEQTMQETVRHSITEAIVA-----------YEEKPRELWIF------------ 1740
Query: 1504 QAFPWQCVLVAEEVVWRAEMEEAL--LEWG-TLAMVSMHMRKLEVLVNFMRAQRASQGGQ 1560
FP Q L + ++ W ++ A LE G A+ H +++ L + G+
Sbjct: 1741 -DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLL----GE 1795
Query: 1561 SLPSVRQTSLLSALLVMAVTHRDI-AQLLEQHQVSDLTD-FHWVRQLKYHLGSPHIIPKS 1618
P RQ + + + V RD+ A+L+ Q QV F W+ QL++
Sbjct: 1796 LPPGDRQK--IMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWED------- 1846
Query: 1619 PLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLA 1676
+ C++++ F Y YEYLG PRL P L +R + L +
Sbjct: 1847 ---------------TQKHCFVNICDAQFQYFYEYLGNSPRLVITP--LTDRCYITLTQS 1889
Query: 1677 LEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWL 1736
L G GP G GK L +ALG + + CS Q++ + + N G +Q GAW
Sbjct: 1890 LHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWG 1949
Query: 1737 LLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVS 1796
++ +++ +LS + ++ +H +A RN + LG + K V
Sbjct: 1950 CFDEFNRISVEVLSVVAVQVKMIH--------DAIRNRK----KRFVFLGEAITLKPSVG 1997
Query: 1797 VRL----GYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMA 1852
+ + GY A + +P NL L RP A+ PD+ + E+ L+ G DA +A
Sbjct: 1998 IFITMNPGY-------AGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALA 2050
Query: 1853 TRLSKFFSLERELVS--GPLPCRLPLLKQILEDTIRTLNVTKEEPKCQ-KPRSLAAIEEA 1909
+ ++L +EL+S L +K +L K P+ Q R+L
Sbjct: 2051 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMP 2110
Query: 1910 ALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKL-MKPLVVEELQQVGLDPS 1968
++ + L GL+ LFP+ L P KL + +V + ++ L P
Sbjct: 2111 KIVTDDIPVFL---------GLVGDLFPA----LDVPRRRKLHFEQMVRQSTLELRLQPE 2157
Query: 1969 PDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEI 2028
+ + QL + L+ + ++G AG+GK+ L + T Q
Sbjct: 2158 ESFILKVVQLEELLAVRHSVFVVGNAGTGKSKI----------LRTLNRTYVNMKQKPVW 2207
Query: 2029 THLYPSGLSPQEFLG--------WLEGS---CWHHGIFPKVLRAAGQCNNMGQKRQTEES 2077
L P ++ E G W +G + G+F +LR + G K
Sbjct: 2208 NDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPK------ 2261
Query: 2078 IGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPT 2137
WI+ DG + W++S+ ++ + L+L S ++IA P LL E+ +P
Sbjct: 2262 -----WIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPA 2316
Query: 2138 VVGCCALVWCGGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFL--T 2194
V +++ + W +++ + + R A L + + VPA L L +
Sbjct: 2317 TVSRAGILYVNPQDLGWNPYVASWI-----DRRRHQSEKANLTILFDKYVPACLDKLRTS 2371
Query: 2195 CQGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQS 2254
+ ++S+ + Q +C +L LL PE++
Sbjct: 2372 FKTITSIPESSLVQTLCV----------LLECLLT------------PENV--------- 2400
Query: 2255 FRSSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDS 2314
D P + E F+FA IW FG L +
Sbjct: 2401 ---------------PSDSPKEVYE-----VYFVFACIWAFGGTLLQDQISDYQADFSRW 2440
Query: 2315 ISRLSNYPEPPPSALVFDLHVSPEDGTLVPFT---GQYLSSHIKGTLGTFHPSIQTERLL 2371
+ + P +FD +V + L+P+ Q+ + +T RL
Sbjct: 2441 WQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLR 2500
Query: 2372 YVVDLLLSGGQPVLLAGEAATGKSAFV-EVLVEPHHPYIYS--PIHPAFSSSHLRLLLSR 2428
Y ++LLL G+P++L G A GK+ FV + L YI S P + +S+ L+ +L +
Sbjct: 2501 YFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEK 2560
Query: 2429 GIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHS 2487
++ + + PG ++ L++ ++D+++ D + QP +RQ +D G Y
Sbjct: 2561 PLEKKAGHNYGPGGNK----KLIYFIDDMNMPEVDLYGTVQP-HTLIRQHIDYGHWYDRQ 2615
Query: 2488 TLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWL 2547
+ L+ + ++A + P + PRL R FTV A + L + I
Sbjct: 2616 KVMLKEIH-NCQYVACMN-PMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHF 2673
Query: 2548 ER---FPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLL 2604
++ PS+ R L++A++ + + F+P+ + HY F+L +S++ + L
Sbjct: 2674 QQQAFAPSILRS---GPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGI-LF 2729
Query: 2605 PNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRE 2664
+ +G +D ++ LWLHE+ R + D+L ++
Sbjct: 2730 ASPECLKGPLD---------------------------LIHLWLHESARVYGDKLIDKKD 2762
Query: 2665 RSYCAKLLLVVAQSVF 2680
+ +L A F
Sbjct: 2763 CDLFQRRMLETAYKYF 2778
Score = 132 bits (332), Expect = 8e-30
Identities = 180/812 (22%), Positives = 325/812 (40%), Gaps = 97/812 (11%)
Query: 2794 KPQMDLISPLLLPVLLLHPQEKPSDLVFSQELI---LGPNSETPNLYLERQWEKLEEQLA 2850
K DL +L + + S ++ Q LI + P+ + WE L+ L
Sbjct: 2760 KKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILT 2819
Query: 2851 TSAA---QLKLSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSI 2907
+ +L + HL QHV R+ R+L P+ LL+ G G+G+ + LA+ +
Sbjct: 2820 ETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLV-GVGGSGKQSLSRLAAYL 2878
Query: 2908 CQAHFFHLPSGSEEAILQCLRDAS---WHAGMLSQPVALLVPSG--VDLTTLHRLLALAT 2962
F + I + D + G + P L+ +D + L + L
Sbjct: 2879 RGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLA 2938
Query: 2963 SGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAH 3022
SG P +++ D+D+I + E + +E + F +V L +
Sbjct: 2939 SGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRT 2998
Query: 3023 KQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSV-PLDDGSWKYPDLQAS 3081
++ + F ++ +ID + W Q AL V++ +E + + P+ S A
Sbjct: 2999 LRVRARKFPAIVNCT--AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISL--FMAH 3054
Query: 3082 IPSVAKAMALIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQ 3141
+ + M+ + H + TPK+FL+ + F L ++ ++ K +R+
Sbjct: 3055 VHTTVNEMSTRYYQNERRHNY-------TTPKSFLEQISLFKNLLKKKQNEVSEKKERLV 3107
Query: 3142 NALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQEN 3201
N ++ L+ T A+ + DL+ +L L + E Q E+ ++
Sbjct: 3108 NGIQKLK-------TTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKT 3160
Query: 3202 LIENLAR-----QRDALQAQREAFLEQMSK-----AFLEPLSQLQVADFEEIRSYRAPPE 3251
+ + R Q + Q QRE + + A L+ L + E++++ PP
Sbjct: 3161 IADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPI 3220
Query: 3252 SVVRVTDAMCDLFH------HETGWASAKQLLC-TEDFYQELVFFPKEKITDS--ELIKL 3302
+V VT A+ L + W +AK + +DF Q L+ + KE I ++ +++
Sbjct: 3221 AVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNE 3280
Query: 3303 HLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQA 3362
H LK P + +R S AA L AW+ ++ + +C P L Q L
Sbjct: 3281 HY-LKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATE 3339
Query: 3363 RLGYYQFQAQETLEHNLA-LAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKA-ALLTPM 3420
+L + + + L+ NL+ L E A A K Q + Q +K A L+ +
Sbjct: 3340 KLEAIRKKLVD-LDRNLSRLTASFEKATAE-----KVRCQEEVNQTNKTIKLANRLVKEL 3393
Query: 3421 RA----WTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLD-EWLALCRGFQE 3475
A W ++ + + T+ GD LL +A + Y+GPF RQEL+ +W+
Sbjct: 3394 EAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFL----- 3448
Query: 3476 ALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAK-SA 3534
Q+ VSIP L ++S+L+ ++ W+ P + S
Sbjct: 3449 --------------QQKVSIPLTEGL-------DLISMLTDDATIAAWNNEGLPSDRMST 3487
Query: 3535 HLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
A +L TH RWPL++DP + + W+
Sbjct: 3488 ENAAIL----THCE--RWPLVIDPQQQGIKWI 3513
Score = 89.7 bits (221), Expect = 6e-17
Identities = 197/984 (20%), Positives = 355/984 (36%), Gaps = 110/984 (11%)
Query: 3740 ELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLL 3799
EL +L+ + + LE Q+L E++ E P+LE L D ++ E+ LL
Sbjct: 3602 ELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLL 3661
Query: 3800 TMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMA 3859
L K + + + + ++ E + + + YRPV
Sbjct: 3662 LRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASL 3721
Query: 3860 MVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLL 3919
+ ++ LQ + PL+ S + + + +A++ + + ED+ + L +T +
Sbjct: 3722 LYFVINDLQKINPLYQFSLKAFNVLFHRAIE-----QADKVEDMQGRISILMESITHAVF 3776
Query: 3920 GSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARP 3979
T+ L + + L +A Q + E++ L L L + H PV +
Sbjct: 3777 --LYTSQALFEKDKLTFLSQMAF-QILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQ 3833
Query: 3980 AWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQ 4039
+W KA + ++ F G+ + G + W+ ++ P + SL+Q
Sbjct: 3834 SWSAIKA------IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQ 3886
Query: 4040 KLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTM-PFKHSQATQPMLILLPPPGHP 4098
KLIL R +RP+ + AL +F LG E T + F+ S P+ +L P
Sbjct: 3887 KLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDA 3946
Query: 4099 SATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCH 4158
L L ++L G+ + G E +V L +A GHW++L N H
Sbjct: 3947 LKDLEILG--KRLGFTIDSGKFHNVSLGQGQE-----TVAEVALEKASKGGHWVILQNVH 3999
Query: 4159 LMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWL---IVPAES 4215
L+ W L +LL R HRD+R+++ P
Sbjct: 4000 LVAKWLGTLEKLL-----------------------ERFSQGSHRDYRVFMSAESAPTPD 4036
Query: 4216 SASLPAVLTQHSMPV--------FWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLL 4267
+P L ++S+ + N L + D++E+ + + + L
Sbjct: 4037 EHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK--EQEFKSILFSLCYF 4094
Query: 4268 HGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQT-QDQLWASLSNPRAAMQELAASVFYGGP 4326
H + R +G + + ++ LT + L A+ P ++ L + YGG
Sbjct: 4095 HACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGH 4154
Query: 4327 LGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECKAQMHLL 4386
+ D DR+ + ++PS + +LA P LD + +L
Sbjct: 4155 ITDDWDRKLCRVYLEEFMNPSLTE------DELMLAPGFAAPPY--LDYAGYHQYIEEML 4206
Query: 4387 PSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQV 4446
P P P L GL + L S L L P Q E +++ L +
Sbjct: 4207 P-PESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDI 4265
Query: 4447 NRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCL 4506
+L + + +++++ + +P+ + V E ++ L+ ++ L+ L
Sbjct: 4266 LEKLPE-EFNMAEIMQKNSNRSPYVL-----------VCFQECERMNILIREIRISLEQL 4313
Query: 4507 LQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYL 4566
LKG S A AL +P W A W LL+R
Sbjct: 4314 DLSLKGELAL-SPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWF------NDLLLRCR 4366
Query: 4567 GVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKR 4626
+ V LS F +P+ L A+ + + +P + +++ + K
Sbjct: 4367 ELDTWTQDLTLPAVVWLSGFFNPQSFLTAI-----MQTMARKNEWPLDKTRLTADVTKKT 4421
Query: 4627 LEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSI 4686
E +P P G L GL + A WD AG + ++ + + PV
Sbjct: 4422 KEDYGHP-------------PREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIF 4468
Query: 4687 STQAPGTSDLPAPADLTVYSCPVY 4710
+ P + Y CPVY
Sbjct: 4469 AKATP----VDRQETKQTYECPVY 4488
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 184 bits (466), Expect = 2e-45
Identities = 321/1616 (19%), Positives = 617/1616 (38%), Gaps = 305/1616 (18%)
Query: 1106 LLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEAR 1165
L++A G+ S + TL LL L + D + + + + ++T++ LQ W
Sbjct: 1389 LMQATGV-SFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGM 1447
Query: 1166 QLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVL 1225
+ + YEP R+ +L S + ++++ +L D + +Q V+
Sbjct: 1448 EFQ---------YEP--HPRTNVPLLCSDE-DLIE------VLED-----NQVQLQNLVM 1484
Query: 1226 SKILAI---EKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQF 1279
SK +A E SG W + + A++ +W Q+ W L + +++ Q
Sbjct: 1485 SKYVAFFLEEVSG--------WQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQL 1536
Query: 1280 PNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELE 1339
P + RF+ +D ++ L D + VV + + ++ + +++
Sbjct: 1537 PQD--SKRFEGIDIDFKEL----AYDAQKIPNVVQTTNKPGLYEKLE----------DIQ 1580
Query: 1340 GIIMSLESVLYGVC----AHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVS 1395
G + E L FPR +FLS S+L+ +L+ + Q + + F ++ +
Sbjct: 1581 GRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMR 1640
Query: 1396 FRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCL 1455
F+ +GE T+T +L + E V P + WL +
Sbjct: 1641 FQLDASGEP----------TKT---SLGMYSKEEEYVAFSEPCDCSGQVEIWLNHV---- 1683
Query: 1456 RLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAE 1515
L HM + V + G + A ++ P++ L+ P Q L
Sbjct: 1684 ---LGHM-KATVRHEMTEGVT---AYEEKPREQWLF-------------DHPAQVALTCT 1723
Query: 1516 EVVWRAE--MEEALLEWGTLAMVSMHMRK----LEVLVNFMRAQRASQGGQSLPSVRQTS 1569
++ W E M A LE G + + + +K L+ L+ + Q + Q + ++
Sbjct: 1724 QIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTI---- 1779
Query: 1570 LLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASS 1629
+ V RD+ + +V + F W+ QL++
Sbjct: 1780 -----CTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDD------------------ 1816
Query: 1630 EPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLG 1687
C+ ++ FLY+YEYLG PRL P L +R + L +L G G
Sbjct: 1817 ----EVKHCFANICDAQFLYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLTMSGAPAG 1870
Query: 1688 PNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPG 1747
P G GK L +ALG + + CS Q++ + N G Q GAW ++ +++
Sbjct: 1871 PAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVE 1930
Query: 1748 LLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVL 1807
+LS + ++ + Q+A R+ + Q F +S+ G + +
Sbjct: 1931 VLSVVAVQVKSI--------QDAIRD-------KKQWFS---FLGEEISLNPSVGIFITM 1972
Query: 1808 R---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERE 1864
A + +P NL L RP A+ +PD + E+ L+ G +A +A + + L +E
Sbjct: 1973 NPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKE 2032
Query: 1865 LVS--GPLPCRLPLLKQILEDTIRTLNVTKEEPKCQ-KPRSLAAIEEAALLRS--PLFSI 1919
L+S L +K +L + P+ Q RSL ++ P+F
Sbjct: 2033 LLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIF-- 2090
Query: 1920 LNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLS 1979
GL+ LFP+ + + LV + + + L + + + QL
Sbjct: 2091 ---------MGLIGDLFPALDVPRRRDPNF---EALVRKAIVDLKLQAEDNFVLKVVQLE 2138
Query: 1980 QALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQ 2039
+ L+ + ++G AG+GK+ SL K + +PV T L P ++
Sbjct: 2139 ELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR---------RPV-WTDLNPKAVTND 2188
Query: 2040 EFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDS 2097
E G + + W G+F ++R + G K WI+ DG + W++S
Sbjct: 2189 ELFGIINPATGEWKDGLFSSIMRELANITHDGPK-----------WILLDGDIDPMWIES 2237
Query: 2098 ITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCI 2156
+ ++ + L+L S ++I P LL E++ +P V +++ + W
Sbjct: 2238 LNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPP 2297
Query: 2157 LSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAE 2216
+S+ + + + T+ ++ L RF ++ + Q
Sbjct: 2298 VSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRF------KKIIPIPEQ--------- 2342
Query: 2217 VTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDK 2276
SM +++ LL+ L ++ A D P +
Sbjct: 2343 --SMVQMVCHLLECLLTTEDIPA--------------------------------DCPKE 2368
Query: 2277 CREHLLAVSSFLFALIWGF-GAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHV 2335
EH F+FA IW F GA + + F + ++ + P +FD ++
Sbjct: 2369 IYEHY-----FVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTV-KFPSQGTIFDYYI 2422
Query: 2336 SPEDGTLVPFT---GQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAAT 2392
PE P++ Q+ + +T R+ Y ++ L++ +PV+L G A T
Sbjct: 2423 DPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGT 2482
Query: 2393 GKSAFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLF 2452
GKS V + P Y + F+ +L ++ + + L++
Sbjct: 2483 GKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIY 2542
Query: 2453 LLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQPTVNFLATVTVPGYCE 2511
++D+++ D + QP +RQ +D G Y S L L+ + V +++ + P
Sbjct: 2543 FIDDMNMPEVDAYGTVQP-HTIIRQHLDYGHWYDRSKLSLKEI-TNVQYVSCMN-PTAGS 2599
Query: 2512 RPLCPRLFRLFTVLALE-------SMTQATLLERHVPIIQAWLERFPSVERERALARGLV 2564
+ PRL R F+V L S + +L +H+ L FP+ ++ L+
Sbjct: 2600 FTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLK-----LGNFPASLQKS--IPPLI 2652
Query: 2565 RASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLR 2624
++ + + F+P+ + HY F+L +++
Sbjct: 2653 DLALAFHQKIATTFLPTGIKFHYIFNLRDFANIF-------------------------- 2686
Query: 2625 RVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
G+ + + + +T +++RL+LHE+ R + D++ ++ K+ V + F
Sbjct: 2687 --QGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTF 2740
Score = 114 bits (286), Expect = 2e-24
Identities = 178/801 (22%), Positives = 316/801 (39%), Gaps = 139/801 (17%)
Query: 2831 SETPNLYLE-------------RQWEKLEEQLATSAA---QLKLSPHLARCHSMAQHVAR 2874
+++PNLY + WE L + L + ++ L +HV
Sbjct: 2750 TQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCH 2809
Query: 2875 LVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDAS--- 2931
+ R+L PR + LL+ G G+G+ + LA+ I F + I D +
Sbjct: 2810 INRILESPRGNALLV-GVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLC 2868
Query: 2932 WHAGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRE--NL 2987
AG+ + L+ D L + L SG P Y++ +++ I ++ E +
Sbjct: 2869 LKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQ 2928
Query: 2988 GVKQNIKK--EMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRYE 3045
G+ N + + + R +Q+ L F +G+K ++ S F ++ +I +
Sbjct: 2929 GLVDNRENCWKFFIDRIRRQLKVTL-CFSPVGNKL---RVRSRKFPAIVNCT--AIHWFH 2982
Query: 3046 PWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLCP 3105
W Q AL V+ L+ + + P ++ SI +K MA +H S +
Sbjct: 2983 EWPQQALESVSLRFLQNTEGIE--------PTVKQSI---SKFMAFVHTSVNQTSQSYLS 3031
Query: 3106 ---ALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLI- 3161
TPK+FL+F+ + L + ++K K +R++N L +K H T A +
Sbjct: 3032 NEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGL------LKLHSTSAQVDD 3085
Query: 3162 ---------FDLEQQLKDSGKSLSMF---QQQLEQSKLLYKQQ--------LEECRHQEN 3201
+L+Q+ +D+ K + + ++ + K + ++ LE + Q++
Sbjct: 3086 LKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKD 3145
Query: 3202 LIENLARQRDALQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMC 3261
E+LA+ AL A + A L+ L + E++S+ +PP +V V+ A+
Sbjct: 3146 CEEDLAKAEPALTAAQAA------------LNTLNKTNLTELKSFGSPPLAVSNVSAAVM 3193
Query: 3262 DLFH------HETGWASAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDA 3314
L + W +AK + D F L+ F KE I ++ L + L+ P +
Sbjct: 3194 VLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPE 3253
Query: 3315 ALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQET 3374
+ S AA L +W+ ++ + C P L + A LT Q +L + +
Sbjct: 3254 FVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHL 3313
Query: 3375 LEHNLALAKMVEDAQASH-------NCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQL 3427
E+ L E A A A T+S A + L + W +
Sbjct: 3314 NENLAKLTARFEKATADKLKCQQEAEVTAVTISLAN-------RLVGGLASENVRWADAV 3366
Query: 3428 QKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQAL 3486
Q K + T+ GD LL +A I YLG F RQ LLD W R + L
Sbjct: 3367 QNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTW----RPYLSQL--------- 3413
Query: 3487 KRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTH 3546
K P+ T + L +L +++ W P + + + + T
Sbjct: 3414 -----------KTPIPVTPA-LDPLRMLMDDADVAAWQNEGLPADRMS------VENATI 3455
Query: 3547 YSSC-RWPLLLDPSNEALIWL 3566
+C RWPL++DP + + W+
Sbjct: 3456 LINCERWPLMVDPQLQGIKWI 3476
Score = 104 bits (260), Expect = 2e-21
Identities = 224/1082 (20%), Positives = 397/1082 (36%), Gaps = 147/1082 (13%)
Query: 3678 LQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPP----------QVQPGFCLYLSTT 3727
+++A G VL+ N+E + L LL RE + + P F L L T
Sbjct: 3498 IEQALEAGAVVLIENLEESID-PVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTK 3556
Query: 3728 LSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDT 3787
L+ + EL +++ + + LE+Q+L ++ E P+LE DL +
Sbjct: 3557 LANPHYQP----ELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGF 3612
Query: 3788 CKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLW 3847
++ E+ LL+ L + + N+ + ++ +E + +++
Sbjct: 3613 KITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAR 3672
Query: 3848 APYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHL 3907
YRP + ++ L + P++ S + + V ++A++ P E L +
Sbjct: 3673 EHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAP-----DESLRERV 3727
Query: 3908 LQLRAHLTRQLLGSTVTALGLTQVPLVGALGALA----LLQATGKASELERLALWPGLAA 3963
L +T + T+ GL + + L L L+ A EL+ L P
Sbjct: 3728 ANLIDSITFSVYQYTIR--GLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTG 3785
Query: 3964 SPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTV 4023
+ S V +L +AW ++L + F L + G + +W+ ++
Sbjct: 3786 TASPVE-----------FLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPE 3834
Query: 4024 LGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLG------RPLDENTYAPTM 4077
P +L Q+L + R +RP+ + AL DF LG R LD T
Sbjct: 3835 KEKLPQEWKNKTAL-QRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFAT----- 3888
Query: 4078 PFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAK--YQQGQKQLQVIALGSEAWDPV 4135
F+ S PM +L P + PL ++ K Y + ++LG
Sbjct: 3889 SFEESGPATPMFFILSPG------VDPLKDVESQGRKLGYTFNNQNFHNVSLGQ---GQE 3939
Query: 4136 SVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPES 4195
V + L A +GHW++L N HL+ W L E+ L++
Sbjct: 3940 VVAEAALDLAAKKGHWVILQNIHLVAKWLSTL-------------------EKKLEEHSE 3980
Query: 4196 RNVSTVHRDFRLWLIV---PAESSASLPAVLTQHSMPV--------FWNQSLELGHVLID 4244
+ H +FR+++ P+ +P + ++S+ + N L + D
Sbjct: 3981 NS----HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQD 4036
Query: 4245 SVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQL 4303
++E+ + + AL H ++ R+ +G + ++ LT V + L
Sbjct: 4037 TLEMCSRETEFKSILFAL--CYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFL 4094
Query: 4304 WASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLAT 4363
A+ P ++ L + YGG + D DR L + L G +++P + L+
Sbjct: 4095 EANAKVPYDDLRYLFGEIMYGGHITDDWDRR----LCRTYL----GEFIRPEMLEGELSL 4146
Query: 4364 LMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPV 4423
P +D + LP P P L GL + L + S L + P
Sbjct: 4147 APGFPLPGNMDYNGYHQYIDAELP-PESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQP- 4204
Query: 4424 WVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEG 4483
R +Q + R +V LE + + +T DE + P + R P
Sbjct: 4205 ------RDSQARDGAGATREEKVKALLEEILERVT-----DEFNIPELMAKVEERTPYIV 4253
Query: 4484 VLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPA 4543
V E ++ L +QR L L LKG S + +AL+ +P W A
Sbjct: 4254 VAFQECGRMNILTREIQRSLRELELGLKGELTMTSHM-ENLQNALYFDMVPESWARRAYP 4312
Query: 4544 GPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALD 4603
W L R + L + G +P V+ L+ F +P+ L A+ +
Sbjct: 4313 STAGLAAWFPDLLNRIKELEAWTG-----DFTMPSTVW-LTGFFNPQSFLTAI-----MQ 4361
Query: 4604 QNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEW 4663
+ +P + ++ + K E +P P G + GL + A W
Sbjct: 4362 STARKNEWPLDQMALQCDMTKKNREEFRSP-------------PREGAYIHGLFMEGACW 4408
Query: 4664 DPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSR 4723
D AG + ++ +P PV P +VYSCPVY G + +
Sbjct: 4409 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ----DCRSVYSCPVYKTSQRGPTYVWTF 4464
Query: 4724 NI 4725
N+
Sbjct: 4465 NL 4466
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 179 bits (454), Expect = 6e-44
Identities = 258/1268 (20%), Positives = 478/1268 (37%), Gaps = 178/1268 (14%)
Query: 912 WEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGL-LAKALSGPFMDPTQDQRST 970
WE + L+S + + +L + L + L L+GP + Q ++
Sbjct: 1306 WEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEAS 1365
Query: 971 EHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQ-------QQRIWH 1023
+ +L+ + QF N ++ Y +T E LP +++ Q+I+
Sbjct: 1366 D-RLIMFQNQFDN-------IYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYT 1417
Query: 1024 LYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRILGEF 1083
LY + E ++ + + +++ + + + ++ L+ L +I+ +F
Sbjct: 1418 LYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLD-LKKIIDDF 1476
Query: 1084 RSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQ 1143
PLL + S + + + G E L ++ PLL++ + I +
Sbjct: 1477 SECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICI 1536
Query: 1144 NENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDS 1203
+ + ++ ++++ W+ + +F K
Sbjct: 1537 SAVKERDIEQKLKQVINEWDNKTFTFGSF----------------------------KTR 1568
Query: 1204 GTFIL--SDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTF 1261
G +L S + ++++SL +L +L+ + +WV + ++E W+T
Sbjct: 1569 GELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTV 1628
Query: 1262 QQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPY 1321
Q WI+L V I RF +D + +M + P V+ V
Sbjct: 1629 QNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETL--- 1685
Query: 1322 FQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQ 1381
GQ L LL +LE SL L FPR FF+SD L+ +L +S Q
Sbjct: 1686 --GQLLPHLLD----QLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQ 1739
Query: 1382 LWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLH 1441
+ F ++ +V F EK D L++ GE ++L P+
Sbjct: 1740 AHLLNVFDNIKSVKFH-----EKIYD------------RILSISSQEGETIELDKPVMAE 1782
Query: 1442 PDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWID 1501
++ WL SL + + +L +++ A G L E L
Sbjct: 1783 GNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLS------------------- 1823
Query: 1502 LVQAFPWQCVLVAEEVVWRAEMEEAL--LEWGTLAMVSMHMRKLEVLVNFMRAQRASQGG 1559
+FP Q L+ +++W + EEAL ++ M + LE+L +
Sbjct: 1824 ---SFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTT----- 1875
Query: 1560 QSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSP 1619
+ L S + L+ + V RDI L + DF W++Q +++
Sbjct: 1876 RDLSSTERVKY-ETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNE-------- 1926
Query: 1620 LQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEE 1679
S+ + I + +F+Y E+LG + + L +R + L AL
Sbjct: 1927 --------DSDKMM------IHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGM 1972
Query: 1680 VACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLE 1739
G GP G GK + + LG+ +V+ CS Q++ + L G Q G+W +
Sbjct: 1973 SMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFD 2032
Query: 1740 KVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRL 1799
+ +++ +LS Q++ + L + S I F + +V++
Sbjct: 2033 EFNRIDLPVLSVAAQQISII------LTCKKEHKKSFI-----------FTDGDNVTMNP 2075
Query: 1800 GYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLS 1856
+G L + A +P NL + R VA+ +PD + + + L G D +A +
Sbjct: 2076 EFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFF 2135
Query: 1857 KFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPL 1916
+ L E +S + L+ IL +RTL K P + +LR
Sbjct: 2136 TLYKLCEEQLSKQVHYDFG-LRNIL-SVLRTLGAAKR----ANPMDTESTIVMRVLRDMN 2189
Query: 1917 FSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLE 1976
S L L+ LFP+ +L + Y ++ + ++++ GL P +
Sbjct: 2190 LSKLIDEDEPLFLSLIEDLFPN---ILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVI 2246
Query: 1977 QLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGL 2036
QL + G++ LGP+G+GKTTC H+L + AM D +P + P +
Sbjct: 2247 QLFETQRVRHGMMTLGPSGAGKTTCIHTLMR------AMTDCG----KPHREMRMNPKAI 2296
Query: 2037 SPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAW 2094
+ + G L+ + W GIF + R + G WII DG + W
Sbjct: 2297 TAPQMFGRLDVATNDWTDGIFSTLWR-----------KTLRAKKGEHIWIILDGPVDAIW 2345
Query: 2095 LDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGE-QTW 2153
++++ +L + L+L +G +I P ++ E + SP V +V+ W
Sbjct: 2346 IENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDW 2405
Query: 2154 QCILSALM 2161
IL +
Sbjct: 2406 SPILEGFL 2413
Score = 101 bits (252), Expect = 2e-20
Identities = 145/744 (19%), Positives = 302/744 (40%), Gaps = 114/744 (15%)
Query: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLP---SGSEEAILQCL 2927
H+ ++ RV+ P+ + LL+ G G+G+ + LAS I F + S + +++ L
Sbjct: 2937 HLVKISRVIRTPQGNALLV-GVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDL 2995
Query: 2928 RDASWHAGMLSQPVALLVPSGV--DLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRE 2985
+ AG + + + D + L + + +SG + ++D I L
Sbjct: 2996 KVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASV 3055
Query: 2986 NLGVKQNIKK-----EMVLQRFHQQVCSHLHL---FFLIGDKQAHKQLPSTLFLRLLQLA 3037
+K+ + E + F +V +LH+ F +G+K ++ L + +
Sbjct: 3056 ---MKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALI-----S 3107
Query: 3038 TASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSAT 3097
+ID + W + AL V++H L S +D ++ + S +A
Sbjct: 3108 GCTIDWFSRWPKDALVAVSEHFL---TSYDIDCSLEIKKEVVQCMGSFQDGVA---EKCV 3161
Query: 3098 HYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTH 3157
Y + + VTPK++L F+ + + + ++++ A R+ LE L+ +
Sbjct: 3162 DYFQRFRRSTH-VTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAAL 3220
Query: 3158 ANLIFDLEQQLKDSGKSLSMFQQQL---EQSKLLYKQQLEECRHQ-ENLIENLARQRDAL 3213
+ + E++L+ + M +++ Q+ K ++++ + + + +++++++ +
Sbjct: 3221 SKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIA 3280
Query: 3214 QAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHET----- 3268
+ + EA + +A L ++ +D +R+ PP ++R+ D + LF +
Sbjct: 3281 EEKLEAAKPALEEA-EAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKI 3339
Query: 3269 ---------GWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAV 3319
W + +L+ +F Q L FPK+ I + + L + P + + V
Sbjct: 3340 DLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRV 3399
Query: 3320 SRPAASLAAWLWAVLHYGLAHCRGLP--TDLL------------LQQVEATLTREQARLG 3365
A L +W A+ + + LP +L+ LQ+ +A L +QA L
Sbjct: 3400 CGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELD 3459
Query: 3366 YYQFQAQETLEHNLALAKMVEDAQASHNCV--AKTLSQAQCGQYHKWPMKAALLTPMRAW 3423
Q + ++ + L +EDA+ + + A TL G+ + W
Sbjct: 3460 VVQAEYEQAMTEKQTL---LEDAERCRHKMQTASTLISGLAGEKER-------------W 3503
Query: 3424 TTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVA 3483
T Q Q+ + + GD LL +A + Y GPF R LL++W
Sbjct: 3504 TEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDW----------------- 3546
Query: 3484 QALKRKQKSVSIP-PKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLR 3542
+++ K+ IP KN ++ +L +W+ P + G+++
Sbjct: 3547 ---RKEMKARKIPFGKN--------LNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVT 3595
Query: 3543 SPTHYSSCRWPLLLDPSNEALIWL 3566
+ R+PLL+DP + IW+
Sbjct: 3596 -----KASRYPLLIDPQTQGKIWI 3614
Score = 68.6 bits (166), Expect = 1e-10
Identities = 86/402 (21%), Positives = 159/402 (39%), Gaps = 38/402 (9%)
Query: 2287 FLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPP-PSALVFDLHVSPEDGTLVPF 2345
F+FAL+W GA L + ++R + P P P FD +V+P DGT +
Sbjct: 2484 FVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAP-DGTWTHW 2542
Query: 2346 ---TGQYL-SSHIKGTLGTFH-PSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV 2400
T +YL S G+ P++ R +++ + G+ VLL GE T K+ ++
Sbjct: 2543 NTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKG 2602
Query: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA 2460
+ + P + FSS+ L+ R I+ + + + ++D+++
Sbjct: 2603 FMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMP 2662
Query: 2461 TSDPEKSCQPVLETLRQAMDGTVYAHSTLELQ-TLQPTVNFLATVTVPGYCERPLCPRLF 2519
+ E Q E +RQ M+ + + + T + FLA + PG + RL
Sbjct: 2663 IIN-EWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLK 2721
Query: 2520 RLFTVLALESMTQATLLERHVPI-IQAWLERFPSVERERALARGLVRASVEAWEAVCNCF 2578
R F++ ++A++ + I + + + E R LV + W+
Sbjct: 2722 RQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM 2781
Query: 2579 MPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMM 2638
+P+P HY F+L +S R G+ T V+
Sbjct: 2782 LPTPAKFHYVFNLRDLS----------------------------RVWQGMLNTTSEVIK 2813
Query: 2639 ATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
++++LW HE +R DR + ++ K L+ + + F
Sbjct: 2814 EPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEF 2855
Score = 58.2 bits (139), Expect = 2e-07
Identities = 122/643 (18%), Positives = 223/643 (34%), Gaps = 68/643 (10%)
Query: 3716 VQPGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELET 3775
V GF LY++T L A E+ +++D + M+ LE+Q+L ++ E ELE
Sbjct: 3686 VLDGFRLYITTKLPNPAYTP----EISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEK 3741
Query: 3776 RWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEE 3835
L + ++ E+ LL L + + + + ++ E
Sbjct: 3742 ERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEI 3801
Query: 3836 LEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPR 3895
++Q YRPV G + +++++ + ++ S +L + +L
Sbjct: 3802 SAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKS 3861
Query: 3896 EINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERL 3955
I + + + H+T ++ L L L L + + E L
Sbjct: 3862 PIT-----SKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFL 3916
Query: 3956 ALWPGLAA-SPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQ 4014
L G A+ KP W+ W L L F + ++ + W+
Sbjct: 3917 TLIKGGASLDLKACPPKP------SKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWK 3970
Query: 4015 AYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYA 4074
+ + P P + L ++L+L R P+ + +G E
Sbjct: 3971 IWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVIL 4030
Query: 4075 P-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWD 4133
++ S P++ LL P+ ++ L K+ +Y + +V A
Sbjct: 4031 DLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHAR------ 4084
Query: 4134 PVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQP 4193
L Q M G W +L NCHL + EL+ +++E
Sbjct: 4085 ------KLLQQTMANGGWALLQNCHLGLDFMDELMDIIIE-------------------- 4118
Query: 4194 ESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWN---QSLELGHVLIDSVELAQ 4250
VH FRLW+ E+ P L Q S+ F N Q L G S ++Q
Sbjct: 4119 ----TELVHDAFRLWM--TTEAHKQFPITLLQMSIK-FANDPPQGLRAGLKRTYS-GVSQ 4170
Query: 4251 QVLYMQPPTQALPLL----LLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQ----TQDQ 4302
+L + +Q P+L LH + R+ +G ++Q +Q D
Sbjct: 4171 DLLDVSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDD 4230
Query: 4303 LWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLS 4345
+ ++ + + YGG + D D+ L + + S
Sbjct: 4231 MDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFS 4273
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 176 bits (445), Expect = 6e-43
Identities = 333/1714 (19%), Positives = 637/1714 (37%), Gaps = 291/1714 (16%)
Query: 1002 ETPVP----LPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLT 1057
E PVP L C R + + +W + V++ +I +WK + + E+ +
Sbjct: 1269 EVPVPDYKQLKACH-REVRLLKELWDMVVVVNTSIEDWKTTKWKDINV----EQMDIDCK 1323
Query: 1058 EAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSL---NCQCLLRALGLGS 1114
+ A+ +L+ + + ++ + L + L ++ + Q L++A +
Sbjct: 1324 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQV-K 1382
Query: 1115 LQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFIL 1174
+ E TL LL L + D + + + ++ ++ L W + +
Sbjct: 1383 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ------ 1436
Query: 1175 HVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKS 1234
H P+ +GT +L L ++++++ L ++ +
Sbjct: 1437 HEPHPR----------------------TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYL 1474
Query: 1235 GDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVM 1291
K W + +++ +W Q+ W L + +++ Q P + RF +
Sbjct: 1475 AHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGD--SQRFDDI 1532
Query: 1292 DDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYG 1351
+ +++ LM +V P V+ A P L L+A L +L L
Sbjct: 1533 NQEFKALMEDAVKTPNVVE-----ATSKP-----GLYNKLEALKKSLAICEKALAEYLET 1582
Query: 1352 VCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWES 1411
FPR +F+S ++L+ +L+ + E + + F + + FR
Sbjct: 1583 KRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFR-------------- 1628
Query: 1412 SPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARL 1471
L A + +K+ L ++ +++ ++C V + V R+
Sbjct: 1629 -------------LDASDKPLKVG--LGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRM 1673
Query: 1472 ARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEAL--LE 1529
++P+ Y + + WI +P Q L ++ W E+ A LE
Sbjct: 1674 C-----STLRHEIPEAVVTYEEKPREQWI---LDYPAQVALTCTQIWWTTEVGLAFARLE 1725
Query: 1530 WGTLAMVSMHMRK----LEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIA 1585
G + + +K L VL+ + + + ++ + V RD+
Sbjct: 1726 EGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTI---------CTIDVHARDVV 1776
Query: 1586 QLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGR 1645
+ +V F W QL++ C+ ++
Sbjct: 1777 AKMIVAKVESSQAFTWQAQLRHRWDE----------------------EKRHCFANICDA 1814
Query: 1646 SFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQA 1703
Y+YEYLG PRL P L +R + L +L + G GP G GK L +A
Sbjct: 1815 QIQYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRA 1872
Query: 1704 LGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLY 1763
LG + + CS Q++ + N G Q GAW ++ +++ +LS + ++
Sbjct: 1873 LGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQV------- 1925
Query: 1764 APLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVPANLHLLLR 1823
Q+A R +++G +++ GY A + +P NL L R
Sbjct: 1926 -KCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGY-------AGRAELPENLKALFR 1977
Query: 1824 PVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILED 1883
P A+ +PD + E+ L+ G +A +A + ++L +EL+S KQ D
Sbjct: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS----------KQDHYD 2027
Query: 1884 ----TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNL---RGLLCALF 1936
I+++ V K P + E+ L+R+ + + +L GL+ LF
Sbjct: 2028 WGLRAIKSVLVVAGSLKRGDP---SRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLF 2084
Query: 1937 PSASQVLAEPMTY-KLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAG 1995
P+ + + K++K +VE + L + + QL + L + ++G AG
Sbjct: 2085 PALDVPRKRDLNFEKIIKQSIVE----LKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAG 2140
Query: 1996 SGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHG 2053
SGK+ SL K L +PV + L P ++ E G + W G
Sbjct: 2141 SGKSQVLKSLNKTYQNLKR---------KPVAVD-LDPKAVTCDELFGIINPVTREWKDG 2190
Query: 2054 IFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSG 2113
+F ++R + G K WII DG + W++S+ ++ + L+L S
Sbjct: 2191 LFSTIMRDLANITHDGPK-----------WIILDGDIDPMWIESLNTVMDDNKVLTLASN 2239
Query: 2114 QQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCILSALMASLPYEYRLQH 2172
++I L+ E++ +P V +++ + W ++S+ + E R
Sbjct: 2240 ERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWI-----ERRKVQ 2294
Query: 2173 RTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHL 2232
A L + + +P L L G + V E+T + IL+ L L
Sbjct: 2295 SEKANLMILFDKYLPTCLDKLRF-GFKKI----------TPVPEITVIQTILYLLECL-- 2341
Query: 2233 RLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALI 2292
L E+ P PD RE L F+F
Sbjct: 2342 -LTEKTVP---------------------------------PDSPRE--LYELYFVFTCF 2365
Query: 2293 WGF-GAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDGTLVPFTGQYLS 2351
W F GA + F + I+ + P +FD ++ P+ +P+T + S
Sbjct: 2366 WAFGGAMFQDQLVDYRVEFSKWWINEFKTI-KFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2424
Query: 2352 SHIKGTL---GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEPHHPY 2408
+ + + + +T R+ Y +DLL+ PV+L G A TGKS + +E +
Sbjct: 2425 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTD 2484
Query: 2409 IYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSC 2468
Y F+ +L ++ + + L++ ++D+++ D +
Sbjct: 2485 NYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTV 2544
Query: 2469 QPVLETLRQAMDGT-VYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLAL 2527
P +RQ MD Y L L+ + ++A + P + RL R F V A+
Sbjct: 2545 AP-HTLIRQHMDHRHWYDRHKLTLKDIH-NCQYVACMN-PTSGSFTIDSRLQRHFCVFAV 2601
Query: 2528 ESMTQATLLERHVPIIQAWLERFPSVERE-RALARGLVRASVEAWEAVCNCFMPSPLHPH 2586
Q L + I+ L F SV + ++ LV A++ + + F+P+ + H
Sbjct: 2602 SFPGQEALTTIYNTILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFH 2660
Query: 2587 YHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRL 2646
Y F+L +S++ GL + V+ ++VRL
Sbjct: 2661 YVFNLRDLSNIF----------------------------QGLLFSTAEVLKTPLDLVRL 2692
Query: 2647 WLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
WLHE +R + D++ +++ ++ + + F
Sbjct: 2693 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2726
Score = 122 bits (307), Expect = 6e-27
Identities = 158/722 (21%), Positives = 293/722 (40%), Gaps = 78/722 (10%)
Query: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDA 2930
H+ R+ R+L PR + LL+ G G+G+ + LA+ I F + I D
Sbjct: 2791 HICRINRILESPRGNALLV-GVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDL 2849
Query: 2931 SWH---AGMLSQP-VALLVPSGVD----LTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982
+ A + + P V L+ S V L ++ LLA SG PG + E +++ I +
Sbjct: 2850 AAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLA---SGEIPGLFMEDEVENIISSM 2906
Query: 2983 PRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042
+ + N +E + F ++V L + + ++ + F ++ +ID
Sbjct: 2907 RPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCT--AID 2964
Query: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102
+ W + AL V+ LE + +P+ S + + + + M+ ++L+ + +
Sbjct: 2965 WFHEWPEDALVSVSARFLEETEGIPVIKASISF--FMSYVHTTVNEMSRVYLATERRYNY 3022
Query: 3103 LCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIF 3162
TPKTFL+ + + L + ++ K +R++N L L+ + +
Sbjct: 3023 -------TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3075
Query: 3163 DLEQQLKDSGKSLSMFQQQ--LEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAF 3220
E +LK +S Q +E K+ ++ + + +E +E + + Q E
Sbjct: 3076 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD--QEEVKVEVINKNVTEKQKACETD 3133
Query: 3221 LEQMSKAFL---EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FHHETGWA 3271
L + A L E L L + E++S+ +PP++VV VT A+ L + W
Sbjct: 3134 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWK 3193
Query: 3272 SAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWL 3330
+AK ++ D F L F KE I ++ L P D +R+ S AA L +W
Sbjct: 3194 AAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWC 3253
Query: 3331 WAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQA 3390
++ + +C P L++ A L Q +L + + E + L E A A
Sbjct: 3254 INIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATA 3313
Query: 3391 SHNCVAKTLSQAQCGQYHKWPMKA-----ALLTPMRAWTTQLQKLKGRCMTVFGDTLLCS 3445
K Q + ++ + A L + W ++ + + +T+ GD LL S
Sbjct: 3314 E-----KIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS 3368
Query: 3446 AAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLAT 3504
A + Y+G F R EL+++ W+ + V IP N L
Sbjct: 3369 AFVSYVGYFTKKYRNELMEKFWIPYIHNLK------------------VPIPITNGL--- 3407
Query: 3505 HSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALI 3564
LSLL+ +++ W+ P + + +L + RWPL++D + +
Sbjct: 3408 ----DPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTE-----RWPLIVDAQLQGIK 3458
Query: 3565 WL 3566
W+
Sbjct: 3459 WI 3460
Score = 72.4 bits (176), Expect = 1e-11
Identities = 192/975 (19%), Positives = 346/975 (35%), Gaps = 126/975 (12%)
Query: 3757 LEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFL 3816
LE+Q+L ++ +E P+LE +L + ++ E+ LL L + +
Sbjct: 3566 LEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3625
Query: 3817 RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCM 3876
N+ + ++ E + +++ YRP + L+ L + P++
Sbjct: 3626 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQF 3685
Query: 3877 SPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV--TALGLTQVPLV 3934
S + + V ++A+ P A+ + Q +LT ++ S TA GL + +
Sbjct: 3686 SLKAFNVVFEKAIQRTTP---------ANEVKQRVINLTDEITYSVYMYTARGLFERDKL 3736
Query: 3935 GALGALALLQATGKAS----ELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHEC 3990
L + + K EL+ L +P A S PV + W G KA E
Sbjct: 3737 IFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVS-----PVDFLQHQGWGGIKALSEM 3791
Query: 3991 EMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPE 4050
+ F L + + G + W+ + + P +L QKL + R LRP+
Sbjct: 3792 D------EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPD 3844
Query: 4051 CLAGALADFTTSLLGRPLDENTYAP-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQ 4109
+ A+ +F +G E + ++ S + + +L P P + L +
Sbjct: 3845 RMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG--K 3902
Query: 4110 KLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQ 4169
KL G+ + G E V + L A +GHW++L N HL+ W
Sbjct: 3903 KLGFTIDNGKLHNVSLGQGQEV-----VAENALDVAAEKGHWVILQNIHLVARW------ 3951
Query: 4170 LLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLI---VPAESSASLP------ 4220
LG LD+ R + H D+R+++ P+ + +P
Sbjct: 3952 -----LG------------TLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILEN 3994
Query: 4221 AVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTR 4280
A+ + P + +L L L M+ L H ++ R+ +G +
Sbjct: 3995 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4054
Query: 4281 LQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISL 4339
++ LT + + L A+ P ++ L + YGG + D DR L
Sbjct: 4055 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRR----L 4110
Query: 4340 TQACLSPSSGSWVQPHTPQS--LLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGL 4397
+ L+ +++ + LLA +P LD + LP P P L GL
Sbjct: 4111 CRTYLA----EYIRTEMLEGDVLLAPGFQIPP--NLDYKGYHEYIDENLP-PESPYLYGL 4163
Query: 4398 SEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDL- 4456
+ L S L + P E+ GA R + ++ LE + +
Sbjct: 4164 HPNAEIGFLTVTSEKLFRTVLEMQP---KETDSGAGTGVSREEKVKAVLDDILEKIPETF 4220
Query: 4457 -LTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPP 4515
+ ++ + P+ V V E ++ L ++R L L LKG
Sbjct: 4221 NMAEIMAKAAEKTPYVV-----------VAFQECERMNILTNEMRRSLKELNLGLKGELT 4269
Query: 4516 CPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSD 4575
+ ++ AL+ +P W A W LL+R + A +
Sbjct: 4270 I-TTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY------ADLLLRIRELEAWTTDF 4322
Query: 4576 VPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLH 4635
L+ F +P+ L A+ + + +P + +S ++ K E + P
Sbjct: 4323 ALPTTVWLAGFFNPQSFLTAI-----MQSMARKNEWPLDKMCLSVEVTKKNREDMTAP-- 4375
Query: 4636 FRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSD 4695
P G + GL + A WD G + ++ + +P PV P
Sbjct: 4376 -----------PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIP---- 4420
Query: 4696 LPAPADLTVYSCPVY 4710
+ +Y CPVY
Sbjct: 4421 VDRMETKNIYECPVY 4435
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 171 bits (434), Expect = 1e-41
Identities = 245/1263 (19%), Positives = 466/1263 (36%), Gaps = 232/1263 (18%)
Query: 952 LAKALSGPFMDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICG 1011
+ + LSG T ++ H +Q+ SD H +++ E+ T + L
Sbjct: 941 MIQTLSGEAASLTNKAKAYSH--------YQDCFSDSQS--HMHSVNVEEITQIVLSEIS 990
Query: 1012 T--RPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELH 1069
+ ++++W EW+ + Q + + + L
Sbjct: 991 DIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLP-K 1049
Query: 1070 SPVLQHCMRILGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTY 1129
S ++ H +++ EF+ LP++ LG+ + + + L +G S+ + + LL
Sbjct: 1050 SDMVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGK-SVPLDKNCKVENLLAL 1108
Query: 1130 PLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQ 1189
+ ++ + IN + + ++ + ++ +W L L ILH
Sbjct: 1109 KMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPL---ILH-------------- 1151
Query: 1190 VLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMH 1249
E+ FI+ ++ ++ES +L+ I G + + EW +
Sbjct: 1152 -----HTEIYS----IFIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLT 1202
Query: 1250 GLGALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVL 1309
LE W+ Q+ W++L V H +I+ F + ++ +M L
Sbjct: 1203 LFSYTLEEWMNCQRNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKKIMSKIQNKQNAL 1262
Query: 1310 SLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVA 1369
+ + + ++LQ ++ LE I SLE L FPR +FLS++EL+
Sbjct: 1263 QITTSAG----------VLEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLD 1312
Query: 1370 LLAARLESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGG 1429
+LA Q + +CF ++ + W+ ++ A G
Sbjct: 1313 ILADSRNPESVQPHLVKCFENIKQLLI------------WKQDIGPPA---VKMLISAEG 1357
Query: 1430 EEVKLQGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNK 1489
E + L + + + +WL ++EK S+ + LK+
Sbjct: 1358 EGLVLPKKIRVRSAVEQWLVNVEK----------------------SMFDVLKK------ 1389
Query: 1490 LYLQLYVQHWIDLVQA---FPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVL 1546
+ Y+ + I L Q+ F CV R ++E+ A + H+ ++ L
Sbjct: 1390 ---ERYIYNIILLFQSQIMFYNDCVKSFVSSYSREKLEKVH------AGLMCHLEEVADL 1440
Query: 1547 VNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLK 1606
V + R ++L ALL++ V RDI L + + DF W R L+
Sbjct: 1441 VVL-----------DTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQ 1489
Query: 1607 YHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLP 1666
Y + C++ SF Y YEYLG + + L
Sbjct: 1490 YKWNEKQKL----------------------CYVSQGNASFTYGYEYLGCTSRLVITPLT 1527
Query: 1667 ERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYL 1726
+R L L+ AL G GP G GK V LA++LG+ V+ C ++ + + +
Sbjct: 1528 DRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFF 1587
Query: 1727 NGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLG 1786
G +Q GAW ++ + + +LS + ++ TI +
Sbjct: 1588 FGLVQSGAWSCFDEFNLIDLEVLSVIASQI------------------LTIKAAKDNYSA 1629
Query: 1787 SSFFEKHHVSVRLGYGCLLVLRALSSA---VPANLHLLLRPVALALPDLRQVAELTLLGA 1843
E + + + + + +P NL L RPVA+ +P + +AE+ L
Sbjct: 1630 RFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSF 1689
Query: 1844 GMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRS- 1902
G + A ++ +L+ + L R+ +S L + L+ + K E KC
Sbjct: 1690 GFKSANSLSGKLTNLYELARKQLSQQDHYNFGL--RSLKIVLIMAGTKKREFKCLSEADE 1747
Query: 1903 ----LAAIEEAALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVE 1958
+ AI EA+L + P + ++ +FP + + + ++ ++
Sbjct: 1748 TLIVIEAIREASLPKCPPEDV------PLFENIIGDIFPEVTVLKVNQLA---LEKVIYT 1798
Query: 1959 ELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFK----------- 2007
QQ+GL + Q L G++L+GP G GKTT L K
Sbjct: 1799 ATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFL 1858
Query: 2008 -IQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQ 2064
+ R +A + + +G V+I L P ++ E G L+ + W G+ +R+
Sbjct: 1859 SVAERKSASKISERKG--KVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVY 1916
Query: 2065 CN--------------------------NMGQKRQTEESIGIQ---------------HW 2083
N + +T+++I + W
Sbjct: 1917 FNTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQW 1976
Query: 2084 IICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCA 2143
II DG + W++++ +L + L L + ++IA ++ EV + + SP V CA
Sbjct: 1977 IILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCA 2036
Query: 2144 LVW 2146
+V+
Sbjct: 2037 MVY 2039
Score = 157 bits (397), Expect = 2e-37
Identities = 161/708 (22%), Positives = 306/708 (43%), Gaps = 69/708 (9%)
Query: 2877 RVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQ---CLRDASWH 2933
R+L+R ++ + G G G+ T TLA + + +P + A ++ + H
Sbjct: 2653 RLLSRELENCFQI-GIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIH 2711
Query: 2934 AGMLSQPVALLVPS-GVDLTT-LHRLLALATSGSFPGQYTEADLDRIGEHLP--RENLGV 2989
AG+ +P L+VP+ ++ + L L + +SG P + +LD I + E G
Sbjct: 2712 AGLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGH 2771
Query: 2990 KQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRYEPWDQ 3049
N ++ +L F +++ +LH+F ++ + + ++ ++ T ID YE W +
Sbjct: 2772 MDN--RQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCT--IDWYERWPE 2827
Query: 3050 AALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLCPALPL 3109
AL VA L+ + V ++ L + + K+M L+ ++ E
Sbjct: 2828 EALLIVANSFLK--EKVNFENRENLKEKLAPTCVQIHKSMK--DLNRKYFEE--TGRFYY 2881
Query: 3110 VTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENL---RMLIKEHGTHANLIF-DLE 3165
TP ++L F++TF + + +++ K R L + L+ E ++ +E
Sbjct: 2882 TTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVE 2941
Query: 3166 QQLKDSG---KSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAFLE 3222
Q+ K++ + L Q +E+ ++L KQ E + ++E+ A++ + ++ L
Sbjct: 2942 QKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKT---ANELKSVLP 2998
Query: 3223 QMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHETGWASAKQLLCTEDF 3282
KA + L+ L AD E+R Y PP V+ V +A+C L + WA+AK LL F
Sbjct: 2999 AFDKAIVA-LNALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKPNWATAKLLLSETGF 3057
Query: 3283 YQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCR 3342
++L+ K+ I D +KL I+ P + + VS SL W+ A+ +Y
Sbjct: 3058 LKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKV 3117
Query: 3343 GLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQASHNCVAKTLSQA 3402
P + + + + L + RL Q Q EH L L +D A +A + A
Sbjct: 3118 VGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMA 3177
Query: 3403 QCGQYHKWPMKAALLTPMR----AWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLR 3458
++ + LLT + W + ++ + + GD LL +A I+Y G P
Sbjct: 3178 S----RRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEF 3233
Query: 3459 RQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSES 3518
RQ ++++W C + +S+ K FS++ +++ +
Sbjct: 3234 RQLIVNKWETFC------------------IENGISLSSK---------FSLIKVMAQKY 3266
Query: 3519 EQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
E +W P + + +L++ + +WPLL+DP +A W+
Sbjct: 3267 EISRWHNQGLPHGQYSVENAILIK-----NGQQWPLLIDPHRQAHKWI 3309
Score = 64.3 bits (155), Expect = 3e-09
Identities = 176/873 (20%), Positives = 304/873 (34%), Gaps = 159/873 (18%)
Query: 3981 WLGPKAWHECEMLEL-LPPFVGLCASLAGHSSAW------QAYLSLSST----------- 4022
WL W +C+ + L PF LC SL + S W +A SL ST
Sbjct: 3685 WLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFKNSKAVYSLISTPFSSENASLEE 3744
Query: 4023 ----------------VLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGR 4066
P P E L+ Q+LIL +VLRPE L ++ F T +G
Sbjct: 3745 NTKPPEETELLNENKETCNPINFPW-EKLTSFQRLILVKVLRPESLNNSVRKFITEKMGN 3803
Query: 4067 PLDENTYAPTM-PFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVI 4125
+ T +K S A P LIL+ G + ++ + A + + + +I
Sbjct: 3804 KYLQRTGVNLKDAYKGSNARTP-LILIQTHG-----IDLTNILLRFAQELKGTTHHVTII 3857
Query: 4126 ALG-SEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADL 4184
+LG +A +++ L++ W+ L NCHL + L
Sbjct: 3858 SLGRDQAAKAEDLILKALTKTQ---QWVFLQNCHLATSFMPRLC---------------- 3898
Query: 4185 ESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHV--- 4241
+++ S NV T+ +FRLWL + SS +P + + V Q L+ +
Sbjct: 3899 ---TIVESFNSPNV-TIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNLLQTF 3954
Query: 4242 -LIDSVELAQQVLYMQPPTQ-----ALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQ 4295
S E+ +++ Q L + ++ R+ YG +++ L
Sbjct: 3955 GCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGV 4014
Query: 4296 VLQT-QDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQP 4354
++ ++ L S A++ L V YGG + D D+ L +L +P
Sbjct: 4015 AIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPE------- 4067
Query: 4355 HTPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPE---PRLCGLSEGPQAWLLRRQSR 4411
L + A K +H++ S P+ P + G+ Q
Sbjct: 4068 -----------VLKDDFSFSRSASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGE 4116
Query: 4412 ALLSALQRSSPVWVPESR--RGAQLAERRLRQRLVQVNRRL------ESLQDLLTHVIRQ 4463
+ L P + R Q + + + L + +RL E + ++
Sbjct: 4117 KFIENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKS 4176
Query: 4464 DESDAPWSVLGPNARR-------PLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPC 4516
S + W L N + L L+ E +L+ + + L L +KG
Sbjct: 4177 MMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKG-EII 4235
Query: 4517 PSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRR---------------GQL 4561
++ + ++ R+P W+ HA +P W+ L +R +
Sbjct: 4236 LTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRR 4295
Query: 4562 LVRYLGVGADASSDVPERVFH-----------------LSAFRHPRRLLLALRGEAALDQ 4604
+R++ V + ++ H L AF P+ L A+ + +
Sbjct: 4296 YMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSR 4355
Query: 4605 N--VPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAE 4662
V + F S ++ K L+ G+ + GL + A
Sbjct: 4356 GIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGAR 4415
Query: 4663 WDPIAGALQDS-PSSQPSPLP-----PVSISTQAPGTSDLPAPADLTVYSCPVYM----G 4712
W+ L+DS P P P IST+ P S+ ++L + CPVY
Sbjct: 4416 WNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPNASN-QTDSELYAFECPVYQTPERS 4474
Query: 4713 GPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
L T L + N + + L TK P+ + RV
Sbjct: 4475 RILATTGLPT-NFLTSVYLSTKKPPSHWITMRV 4506
Score = 51.6 bits (122), Expect = 2e-05
Identities = 58/238 (24%), Positives = 97/238 (40%), Gaps = 40/238 (16%)
Query: 2450 LLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQPTVNFLATVTVPG 2508
+L ++D+++ SD QP LE +RQ +D G VY + +Q A V V
Sbjct: 2465 ILIFIDDMNMPVSDMY-GAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVN 2523
Query: 2509 YCERPLCPRLFRLFTVLALESMTQ---ATLLERHVPIIQAWLERFPSVERERALARGLVR 2565
+ PRL + F++L L +Q T+ + H+ I + P V++ + ++
Sbjct: 2524 ----DISPRLLKHFSMLVLPHPSQDILCTIFQAHLGIYFSINNFTPEVQKSKDQ---IIS 2576
Query: 2566 ASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRR 2625
S+ + V +P+P HY F+L + LL
Sbjct: 2577 CSLAIYHQVRQNMLPTPTKCHYMFNLRDMFKLL--------------------------- 2609
Query: 2626 VSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCG 2683
GL TV+ + L++HEA R F DRL ++S +LL ++ F G
Sbjct: 2610 -LGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCFQIG 2666
Score = 40.4 bits (93), Expect = 0.042
Identities = 60/281 (21%), Positives = 106/281 (37%), Gaps = 46/281 (16%)
Query: 301 APSRYFRPYSLMVVPPDKVN--PEHYIFSPFGILHVHPVEGS----ETMTLGTW---HHH 351
+P + PY L VV E ++ + I V + GS E + W H
Sbjct: 183 SPKSLYNPYDLQVVSAHTAKHCKEFWVITASFISKVINIVGSVKEVELIPTLEWLSERRH 242
Query: 352 CVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHIS 411
L +Q + F+ + K+F WK NV+ + + FL +HL LA F L++I
Sbjct: 243 YYLLRQFKIFSDFR---MNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIR 299
Query: 412 RLLQE-------------LHSVSWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLC 458
L ++ L ++ + + R Y L + ++ +AL+ L N
Sbjct: 300 GLCEDAINLKNYNDHENNLSAICLVKLDSSRTYSLDEFCEEQLQQATQALKQLEDIRNKA 359
Query: 459 TSILR---LVHEDTYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWL 515
S ++ L + +++ + ++ D H +L + + E ++
Sbjct: 360 ISEMKSTFLKVAEKNEIKEYFESKLSEDD-------------TTHFKLPKYRRLLETFF- 405
Query: 516 QLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKPF 556
KF LVDY I Q LI L + + + PF
Sbjct: 406 ---KFVMLVDY-IFQELIRQLMNTAVTLLLELFNGSAGMPF 442
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 162 bits (410), Expect = 7e-39
Identities = 214/978 (21%), Positives = 378/978 (38%), Gaps = 144/978 (14%)
Query: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
+D+G ILS +Q + + + + W + + ++ WL
Sbjct: 848 RDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLK 907
Query: 1261 FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP 1320
Q +W++L + I + +F+ +D +R +M+ DP VL+ +
Sbjct: 908 VQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTG---- 963
Query: 1321 YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA 1380
L + LQ + LE I+ L + L FPR FFLS+ E++ +L+ +
Sbjct: 964 ------LLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRV 1017
Query: 1381 QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL 1440
Q +++CF + + F N D + +VE +A++ ++
Sbjct: 1018 QPHLKKCFEGIAKLEFLP------NLDIKAMYSSEGERVELIALISTSAARGAVE----- 1066
Query: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500
KWL +E L L VH + AARLA S
Sbjct: 1067 -----KWLIQVED-LMLRSVHDV--IAAARLAYPESARR--------------------- 1097
Query: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH---MRKLEVLVNFMRAQRASQ 1557
D V+ +P Q VL ++ W +E +E ++ GT + + +L +V +R + + Q
Sbjct: 1098 DWVREWPGQVVLCISQMFWTSETQE-VISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQ 1156
Query: 1558 GGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPK 1617
+ L AL+ + V RD+ + + VS TDF W+ QL+Y+ + +
Sbjct: 1157 ---------TRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENEN---- 1203
Query: 1618 SPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLL 1675
+ ++ + Y YEYLG PRL P L +R L+
Sbjct: 1204 --------------------ARVRIINCNVKYAYEYLGNSPRLVITP--LTDRCYRTLIG 1241
Query: 1676 ALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAW 1735
A G GP G GK LA+AL Q V+ CS ++ + + G GAW
Sbjct: 1242 AFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAW 1301
Query: 1736 LLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHV 1795
++ +++ +LS + Q++ L + + T+ +L + F +
Sbjct: 1302 ACFDEFNRIELEVLSVVAQQI-----LCIQRAIQQKLVVFVFEGTELKLNPNCFVA---I 1353
Query: 1796 SVRLGYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRL 1855
++ GY A S +P NL +L R VA+ +P+ +AE++L G +A ++ ++
Sbjct: 1354 TMNPGY-------AGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKI 1406
Query: 1856 SKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRS- 1914
+ L E +S + ++ + V K + P E+ LLRS
Sbjct: 1407 VMTYRLCSEQLSSQFHYDYGMR------AVKAVLVAAGNLKLKYPNEN---EDILLLRSI 1457
Query: 1915 -----PLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSP 1969
P F + + + L N G+ LFP A+ Y E L P
Sbjct: 1458 KDVNEPKF-LSHDIPLFN--GITSDLFPGIKLPEAD---YHEFLECAHEACNVHNLQPVK 1511
Query: 1970 DILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEIT 2029
L + Q + + G +L+G + KT H L + L M + + V
Sbjct: 1512 FFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVL---ADTLTLMNEHGYGEEEKVIYR 1568
Query: 2030 HLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087
+ P ++ + G + W GI R +K W++ D
Sbjct: 1569 TVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRK-----------WVVFD 1617
Query: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWC 2147
G + W++S+ +L + +L L SG+ I P L+ E D + SP V C +++
Sbjct: 1618 GPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYL 1677
Query: 2148 GGEQT-WQCILSALMASL 2164
Q W+ ++S+ + SL
Sbjct: 1678 EPSQLGWEPLVSSWLNSL 1695
Score = 88.6 bits (218), Expect = 1e-16
Identities = 191/868 (22%), Positives = 306/868 (35%), Gaps = 114/868 (13%)
Query: 3898 NHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERLAL 3957
N + L L L H T L + +L L L LL A + E + L
Sbjct: 2311 NKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFL 2370
Query: 3958 WPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYL 4017
G V K P WL K+W E P F GL H W+
Sbjct: 2371 LTG------GVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIY 2424
Query: 4018 SLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRP-LDENTYAPT 4076
P P + L+ LQK+I+ R LRP+ + A+ ++ T LG+ ++ + T
Sbjct: 2425 DSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLT 2484
Query: 4077 MPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVS 4136
+ S T P++ +L P P A+L K A + Q I+LG + P++
Sbjct: 2485 KSYLDSNCTIPLIFVLSPGADPMASL------LKFANDKSMSGNKFQAISLG-QGQGPIA 2537
Query: 4137 VVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESR 4196
+ A+ EG W+ L NCHL W L K+ D SE
Sbjct: 2538 --AKMIKAAIEEGTWVCLQNCHLAVSWMPML----------EKICEDFTSE--------- 2576
Query: 4197 NVSTVHRDFRLWLIVPAESSASLPAVLTQHSM------PVFWNQSLELGHVLIDSVELAQ 4250
T + FRLWL + S+ P + Q+ + P +L L L D V +
Sbjct: 2577 ---TCNSSFRLWL--TSYPSSKFPVTILQNGVKMTNEPPTGLRLNL-LQSYLTDPVSDPE 2630
Query: 4251 QVLYMQPPTQALPLLL-----LHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWA 4305
+ A LL H L+ R+ +G +++ L ++ Q QL+
Sbjct: 2631 FFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDL-RISIRQLQLFI 2689
Query: 4306 SLSN--PRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWV--QPHTPQSLL 4361
+ + P A+ L YGG + D DR L+++ L+ ++ PH S
Sbjct: 2690 NEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTM----LADFYNLYIVENPHYKFSPS 2745
Query: 4362 ATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSS 4421
P+ D + K LP P + GL E +Q++ L +L +
Sbjct: 2746 GNYFAPPKGTYEDYIEFIKK----LPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQ 2801
Query: 4422 PVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPL 4481
+ GA + ++ LE +D+L + + + +
Sbjct: 2802 G---GSKQTGASGSTDQI---------LLEITKDILNKLPSDFDIEMALRKYPVRYEESM 2849
Query: 4482 EGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHA 4541
VL E + L+ T++ L L + +KG S A++ +L G++P W +
Sbjct: 2850 NTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDS-ALEALSGSLLVGKVPEIWAKRS 2908
Query: 4542 PAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAA 4601
+P ++ R L + G VF LS F + L A
Sbjct: 2909 YPSLKPLGSYITDFLARLNFLQDWYNSGKPC-------VFWLSGFFFTQAFLTGAMQNYA 2961
Query: 4602 LDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHA 4661
P + G V + + + T PE G+ + GL + A
Sbjct: 2962 RKYTTP-IDLLGYEFEV-------------------IPSDTSDTSPEDGVYIHGLYLDGA 3001
Query: 4662 EWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY----MGGPLGT 4717
WD +G L + L P+ + + + A Y CP+Y G L T
Sbjct: 3002 RWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDA----YVCPLYKTSERKGTLST 3057
Query: 4718 AKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
S N V+ + L T ++R V
Sbjct: 3058 TG-HSTNFVIAMLLKTDQPTRHWIKRGV 3084
Score = 77.4 bits (189), Expect = 3e-13
Identities = 89/415 (21%), Positives = 160/415 (38%), Gaps = 54/415 (13%)
Query: 2287 FLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSA-----------LVFD-LH 2334
F+F+LIW G + +FDTFIR I + P S LV+D ++
Sbjct: 1775 FIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMY 1834
Query: 2335 VSPEDGTLVPFTGQYLSSHIKGTLGTFH----PSIQTERLLYVVDLLLSGGQPVLLAGEA 2390
G V + ++++ P++ T R +++DL ++ +P+L G
Sbjct: 1835 ELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPT 1894
Query: 2391 ATGKSAFVEVLVEPH-HPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPS 2449
TGKS +V+ + H Y P + S+ + I + +
Sbjct: 1895 GTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKK 1954
Query: 2450 LLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQPTVNFLATVTVPG 2508
+ ++D+++ + + QP +E LRQ D G Y TL + +A + PG
Sbjct: 1955 CIIFIDDMNMPALE-KYGAQPPIELLRQFFDCGHWYDLKDTSKITLVD-IELIAAMGPPG 2012
Query: 2509 YCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASV 2568
P+ PR R F + ++ S + T++ I+ +L + +V ++
Sbjct: 2013 GGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTM 2072
Query: 2569 EAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSG 2628
E ++ +P+P HY F+L S +
Sbjct: 2073 EIYKQSVENLLPTPTKSHYTFNLRDFSRV------------------------------- 2101
Query: 2629 LRGTCLTVMMATRN---VVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
+RG L A N ++RL++HE R F DRL + +R + +L V + F
Sbjct: 2102 IRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHF 2156
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 162 bits (410), Expect = 7e-39
Identities = 221/962 (22%), Positives = 379/962 (39%), Gaps = 155/962 (16%)
Query: 1218 IQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVLHEMKI 1277
+++SL VL +L+ + K WV + ++E WL Q W++L V I
Sbjct: 1451 MEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDI 1510
Query: 1278 QFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVE 1337
RF+ +D + +M+ + +P V++ V + + QLL +
Sbjct: 1511 AKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGD---------ETMGQLLPHLHEQ 1561
Query: 1338 LEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397
LE SL L FPR FF+SD L+ +L +S Q PH+ AVS
Sbjct: 1562 LEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQ-------PHLPAVS-- 1612
Query: 1398 SCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRL 1457
N + E + + + +AV+ GE++ L + + WL L K +++
Sbjct: 1613 ------DNIN--EVTFHAKDYDRIMAVISREGEKIVLDNSVMAKGPVEIWLLDLLK-MQM 1663
Query: 1458 ALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEV 1517
+ +H + + A Q+ + L ++ H FP Q L+ ++
Sbjct: 1664 SSLHNI-------------IRSAFYQI-SDSGFQLLPFLSH-------FPAQVGLLGIQM 1702
Query: 1518 VWRAEMEEAL--LEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALL 1575
+W + EEAL + M + + L++L + SQ L + L+
Sbjct: 1703 LWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLI-----SQTTHDLSKFDRVKF-ETLI 1756
Query: 1576 VMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSP 1635
+ V RDI L + + TDF W++Q +++ K L +T+ S
Sbjct: 1757 TIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-------KEDLD--QTVVS------- 1800
Query: 1636 AACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRA 1695
+ F+Y E+LG + + L +R + L AL G GP G GK
Sbjct: 1801 ------ITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTE 1854
Query: 1696 IVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQR 1755
+ + LG+ +V+ CS Q++ + L G Q G+W ++ +++ +LS Q+
Sbjct: 1855 TTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQ 1914
Query: 1756 LGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLR---ALSS 1812
+Y L R I F + V + +G L + A
Sbjct: 1915 ------IYIVLTARKERKKQFI-----------FSDGDCVDLNPEFGIFLTMNPGYAGRQ 1957
Query: 1813 AVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPC 1872
+P NL + R VA+ +PD + + + L G + +A + + L C
Sbjct: 1958 ELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKL----------C 2007
Query: 1873 RLPLLKQILED-TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNLR-- 1929
L KQ+ D +R + R+L + + A S L ++ GL NL
Sbjct: 2008 EEQLTKQVHYDFGLRNI--------LSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKL 2059
Query: 1930 ---------GLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQ 1980
L+ LFP + + TY ++ V ++Q GL P L QL +
Sbjct: 2060 VDEDEPLFLSLINDLFPG---LQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYE 2116
Query: 1981 ALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQE 2040
G++ LGP+GSGKTT L K Q T+ +P + P ++ +
Sbjct: 2117 TSLVRHGLMTLGPSGSGKTTVITILMKAQ----------TECGRPHREMRMNPKAITAPQ 2166
Query: 2041 FLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSI 2098
G L+ + W GIF + R K + E+I ++I DG + W++++
Sbjct: 2167 MFGRLDTATNDWTDGIFSTLWRKT-------LKAKKGENI----FLILDGPVDAIWIENL 2215
Query: 2099 TCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQ-TWQCIL 2157
+L + L+L +G +I P LL EV + SP V +V+ +W+ IL
Sbjct: 2216 NSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPIL 2275
Query: 2158 SA 2159
A
Sbjct: 2276 QA 2277
Score = 83.6 bits (205), Expect = 4e-15
Identities = 167/806 (20%), Positives = 303/806 (37%), Gaps = 127/806 (15%)
Query: 2814 EKPSDLVFSQELILGPNSETPNLY-LERQWEKLEEQLATSAAQLK-----LSPHLARCHS 2867
++P D VF E P +Y L ++ L E+L Q S L
Sbjct: 2748 DEPEDSVF----------EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKD 2797
Query: 2868 MAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLP---SGSEEAIL 2924
H+ ++ R++ R LL G G+G+ + LAS I F + S + +
Sbjct: 2798 AMTHLIKISRII-RTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLT 2856
Query: 2925 QCLRDASWHAGMLSQPVALLVPSGV--DLTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982
L+ AG + + + D L L L +SG + ++D I +
Sbjct: 2857 DDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQ-- 2914
Query: 2983 PRENLGVKQNIKKEM---------VLQRFHQQVCSHLHL---FFLIGDKQAHKQLPSTLF 3030
G+ +K+E+ + + F + +LH+ F +G+K + L F
Sbjct: 2915 -----GLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLK---F 2966
Query: 3031 LRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMA 3090
L+ T +D + W + AL VA + L V + + + +
Sbjct: 2967 PGLISGCT--MDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESC 3024
Query: 3091 LIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRML 3150
+ H VTPK++L F++ + + + + I +A+R+ L+ L
Sbjct: 3025 ESYFQRYRRRAH-------VTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKL--- 3074
Query: 3151 IKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLE------QSKLLYKQQLEECRHQENLIE 3204
++ + A L DL + K+ + + L Q+ K +++E + + +
Sbjct: 3075 MEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKA---Q 3131
Query: 3205 NLARQRDALQAQREAFLEQMSKAFLEP---LSQLQVADFEEIRSYRAPPESVVRVTDAMC 3261
+ + D+ + + E+ LE A E L+ ++ D +R PP ++R+ D +
Sbjct: 3132 KIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVL 3191
Query: 3262 DLFHHET--------------GWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILK 3307
LF + W + +L+ F L FPK+ I + + L
Sbjct: 3192 LLFQKKIDPVTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFN 3251
Query: 3308 APGMDDAALRAVSRPAASLAAWLWAV-LHYGLAHCRGLPTDLLLQQVEATLTREQARLGY 3366
+ + V A L +W A+ + YG+ LP L + E L A LG
Sbjct: 3252 MDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINR-EVLPLKANLAKQEGRLAVANAELG- 3309
Query: 3367 YQFQAQETLEHNLA-LAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRA--- 3422
+AQ L+ A L K+ A+ N L+ A + K + L+ +
Sbjct: 3310 ---KAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCR-KKMQAASTLIDGLSGEKI 3365
Query: 3423 -WTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELL-DEWLALCRGFQEALGPD 3480
WT Q ++ K + + GD LLC+ + YLGPF + R LL D+W
Sbjct: 3366 RWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQW-------------- 3411
Query: 3481 DVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLL 3540
+ + ++ IP L +++S+L +W P + G++
Sbjct: 3412 ------EMELRARKIPFTENL-------NLISMLVDPPTIGEWGLQGLPGDDLSIQNGII 3458
Query: 3541 LRSPTHYSSCRWPLLLDPSNEALIWL 3566
+ T R+PLL+DP + W+
Sbjct: 3459 VTKAT-----RYPLLIDPQTQGKTWI 3479
Score = 57.8 bits (138), Expect = 3e-07
Identities = 97/462 (20%), Positives = 178/462 (38%), Gaps = 52/462 (11%)
Query: 2277 CREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSA--LVFDLH 2334
C EHL + F+F L+W GA L + F+R S+L + PE P + +++ +
Sbjct: 2342 CVEHLHKL--FVFGLMWSLGALLELESREKLEAFLRQHESKL-DLPEIPKGSNQTMYEFY 2398
Query: 2335 VSPE------DGTLVPFTGQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAG 2388
V+ + L P+ Y + I P++ R +++D + + VLL G
Sbjct: 2399 VTDYGDWEHWNKKLQPY--YYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTG 2456
Query: 2389 EAATGKSAFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKP 2448
E T K+ V+ ++ + P + FSS+ ++ R I+ +
Sbjct: 2457 EQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGSTYGPPGGR 2516
Query: 2449 SLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQPTVNFLATVTVP 2507
+ ++D+++ + E Q E +RQ M+ +Y+ T V +A + P
Sbjct: 2517 KMTVFIDDINMPVIN-EWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHP 2575
Query: 2508 GYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERA-LARGLVRA 2566
G + RL R FTV + A++ + I + + S + + + LV
Sbjct: 2576 GGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIVNLVSV 2635
Query: 2567 SVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRV 2626
W+ +P+P HY F+L +S + + +
Sbjct: 2636 GRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAE------------------- 2676
Query: 2627 SGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPR-ERSYCAKLLLVVAQSV-----F 2680
C ++ ++ L+ HE R DR +P E+ + A L V +++
Sbjct: 2677 -----ECASI----PTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAAS 2727
Query: 2681 CCGPGPQHLG--KDHQESEEEEEEERVPEVESEGELAQWEDF 2720
C P P + ++ E +E E+ V EV EL DF
Sbjct: 2728 CILPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDF 2769
Score = 48.9 bits (115), Expect = 1e-04
Identities = 186/1010 (18%), Positives = 342/1010 (33%), Gaps = 130/1010 (12%)
Query: 3720 FCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQD 3779
F LY++T L A + + +V+D + M+ LE Q+L ++ E ELE
Sbjct: 3555 FKLYITTKLPNPAFTPEINAKT----SVIDFTVTMKGLENQLLRRVILTEKQELEAERVK 3610
Query: 3780 LKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQ 3839
L + ++ E+ LL L + + + ++
Sbjct: 3611 LLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAET 3670
Query: 3840 KLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINH 3899
+++ +RP G + ++++ + ++ S +L + Q++ + +
Sbjct: 3671 EIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQ 3730
Query: 3900 GEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWP 3959
+ + +LT ++ +V L L L L + G E AL
Sbjct: 3731 -----KRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIK 3785
Query: 3960 GLAA-SPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLS 4018
G AA KP W+ W L LP F + ++ + W+++
Sbjct: 3786 GGAALDLKACPPKPY------RWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFD 3839
Query: 4019 LSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTM- 4077
+ P + L KL+L R P+ + + L+E P +
Sbjct: 3840 KDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKY----IADSLEEKYTEPVIL 3895
Query: 4078 ----PFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAK-YQQGQKQLQVIALGSEAW 4132
++ S P++ L P+ + L KL + GQ Q +V A
Sbjct: 3896 NLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECRTISMGQGQ-EVHAR----- 3949
Query: 4133 DPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQ 4192
+ +M +G W++L NCHL + +ELL+ L+
Sbjct: 3950 -------KLIQMSMQQGGWVLLQNCHLGLEFMEELLETLI-------------------- 3982
Query: 4193 PESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWN---QSLELGHVLIDSVELA 4249
FR+W + E P L Q S+ F N Q + G + +
Sbjct: 3983 ----TTEASDDSFRVW--ITTEPHDRFPITLLQTSLK-FTNEPPQGVRAG-LKRTFAGIN 4034
Query: 4250 QQVLYMQPPTQALPLL----LLHGLLLHRQLYGT---RLQAHRGRWSQVTLTQVLQTQ-D 4301
Q +L + P+L LH + R+ +G + Q +Q D
Sbjct: 4035 QDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLD 4094
Query: 4302 QLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLL 4361
+ ++ + V YGG + D D+ L + S + P
Sbjct: 4095 ECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSE------KMFEPSFCF 4148
Query: 4362 ATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSS 4421
T +P + LD E + LPS P + GL + QS + L+ +
Sbjct: 4149 YTGYKIPLCKTLDQYFE---YIQSLPSLDNPEVFGLHPNAD---ITYQSNTASAVLETIT 4202
Query: 4422 PVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPL 4481
+ ES G + RL + + + D + H ++ ++ +
Sbjct: 4203 NIQPKESGGGVGETREAIVYRLSE-DMLSKLPPDYIPHEVKS-------RLIKMGHLNSM 4254
Query: 4482 EGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHA 4541
L E + +++ L+ L L ++G S ++ R+P W+
Sbjct: 4255 NIFLRQEIDRMQRVISILRSSLSDLKLAIEGT-IIMSENLRDALDNMYDARIPQLWK-RV 4312
Query: 4542 PAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAA 4601
W +L R ++ G VF ++ F +P+ L A+R
Sbjct: 4313 SWDSSTLGFWFTELLERNAQFSTWIFEGR-------PNVFWMTGFFNPQGFLTAMR---- 4361
Query: 4602 LDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHA 4661
Q V ++ + +V+ +++ L E +P P G+ + GL + A
Sbjct: 4362 --QEVTRAHKGWALDTVT---------IHNEVLRQTKEEITSP--PGEGVYIYGLYMDGA 4408
Query: 4662 EWDPIAGALQDS-PSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710
WD G L +S P + LP + I + AP D +Y CP+Y
Sbjct: 4409 AWDRRNGKLMESTPKVLFTQLPVLHIF-----AINSTAPKDPKLYVCPIY 4453
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 158 bits (399), Expect = 1e-37
Identities = 230/1062 (21%), Positives = 415/1062 (39%), Gaps = 161/1062 (15%)
Query: 1638 CWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRA 1695
C+ ++ Y+YEYLG PRL P L +R + L +L + G GP G GK
Sbjct: 1784 CFANICDAQIQYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLIMGGAPAGPAGTGKTE 1841
Query: 1696 IVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQR 1755
L +ALG + + CS Q++ + N G Q GAW ++ +++ +LS + +
Sbjct: 1842 TTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQ 1901
Query: 1756 LGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVP 1815
+ Q+A R +++G +++ GY A + +P
Sbjct: 1902 V--------KCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGY-------AGRAELP 1946
Query: 1816 ANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLP 1875
NL L RP A+ +PD + E+ L+ G +A +A + ++L +EL+S
Sbjct: 1947 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS-------- 1998
Query: 1876 LLKQILED----TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNL--- 1928
KQ D I+++ V K P + E+ L+R+ + + +L
Sbjct: 1999 --KQDHYDWGLRAIKSVLVVAGSLKRGDP---SRAEDQVLMRALRDFNIPKIVTDDLPVF 2053
Query: 1929 RGLLCALFPSASQVLAEPMTY-KLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASG 1987
GL+ LFP+ + + K++K +VE + L + + QL + L
Sbjct: 2054 MGLIGDLFPALDVPRKRDLNFEKIIKQSIVE----LKLQAEDSFVLKVVQLEELLQVRHS 2109
Query: 1988 ILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEG 2047
+ ++G AGSGK+ SL K L +PV + L P ++ E G +
Sbjct: 2110 VFIVGNAGSGKSQVLKSLNKTYQNLKR---------KPVAVD-LDPKAVTCDELFGIINP 2159
Query: 2048 SC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSEL 2105
W G+F ++R + G K WII DG + W++S+ ++ +
Sbjct: 2160 VTREWKDGLFSTIMRDLANITHDGPK-----------WIILDGDIDPMWIESLNTVMDDN 2208
Query: 2106 PQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCILSALMASL 2164
L+L S ++I L+ E++ +P V +++ + W ++S+ +
Sbjct: 2209 KVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWI--- 2265
Query: 2165 PYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARIL 2224
E R A L + + +P L L G + V E+T + IL
Sbjct: 2266 --ERRKVQSEKANLMILFDKYLPTCLDKLRF-GFKKI----------TPVPEITVIQTIL 2312
Query: 2225 HSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAV 2284
+ L L L E+ P PD RE L
Sbjct: 2313 YLLECL---LTEKTVP---------------------------------PDSPRE--LYE 2334
Query: 2285 SSFLFALIWGF-GAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDGTLV 2343
F+F W F GA + F + I+ + P +FD ++ P+ +
Sbjct: 2335 LYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTI-KFPSQGTIFDYYIDPDTKKFL 2393
Query: 2344 PFTGQYLSSHIKGTL---GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV 2400
P+T + S + + + + +T R+ Y +DLL+ PV+L G A TGKS +
Sbjct: 2394 PWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGD 2453
Query: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA 2460
+E + Y F+ +L ++ + + L++ ++D+++
Sbjct: 2454 KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMP 2513
Query: 2461 TSDPEKSCQPVLETLRQAMDGT-VYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLF 2519
D + P +RQ MD Y L L+ + ++A + P + RL
Sbjct: 2514 EVDKYGTVAP-HTLIRQHMDHRHWYDRHKLTLKDIH-NCQYVACMN-PTSGSFTIDSRLQ 2570
Query: 2520 RLFTVLALESMTQATLLERHVPIIQAWLERFPSVERE-RALARGLVRASVEAWEAVCNCF 2578
R F V A+ Q L + I+ L F SV + ++ LV A++ + + F
Sbjct: 2571 RHFCVFAVSFPGQEALTTIYNTILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATF 2629
Query: 2579 MPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMM 2638
+P+ + HY F+L +S++ GL + V+
Sbjct: 2630 LPTAIKFHYVFNLRDLSNIF----------------------------QGLLFSTAEVLK 2661
Query: 2639 ATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
++VRLWLHE +R + D++ +++ ++ + + F
Sbjct: 2662 TPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2703
Score = 119 bits (298), Expect = 7e-26
Identities = 157/722 (21%), Positives = 292/722 (40%), Gaps = 77/722 (10%)
Query: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDA 2930
H+ R+ R+L PR + LL+ G G+G+ + LA+ I F + I D
Sbjct: 2768 HICRINRILESPRGNALLV-GVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDL 2826
Query: 2931 SWH---AGMLSQP-VALLVPSGVD----LTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982
+ A + + P V L+ S V L ++ LLA SG PG + E +++ I +
Sbjct: 2827 AAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLA---SGEIPGLFMEDEVENIISSM 2883
Query: 2983 PRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042
+ + N +E + F ++V L + + ++ + F ++ +ID
Sbjct: 2884 RPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCT--AID 2941
Query: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102
+ W + AL V+ LE + +P + + + + + M+ ++L+ + +
Sbjct: 2942 WFHEWPEDALVSVSARFLEETEGIPWEVKA-SISFFMSYVHTTVNEMSRVYLATERRYNY 3000
Query: 3103 LCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIF 3162
TPKTFL+ + + L + ++ K +R++N L L+ + +
Sbjct: 3001 -------TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053
Query: 3163 DLEQQLKDSGKSLSMFQQQ--LEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAF 3220
E +LK +S Q +E K+ ++ + + +E +E + + Q E
Sbjct: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD--QEEVKVEVINKNVTEKQKACETD 3111
Query: 3221 LEQMSKAFL---EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FHHETGWA 3271
L + A L E L L + E++S+ +PP++VV VT A+ L + W
Sbjct: 3112 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWK 3171
Query: 3272 SAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWL 3330
+AK ++ D F L F KE I ++ L P D +R+ S AA L +W
Sbjct: 3172 AAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWC 3231
Query: 3331 WAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQA 3390
++ + +C P L++ A L Q +L + + E + L E A A
Sbjct: 3232 INIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATA 3291
Query: 3391 SHNCVAKTLSQAQCGQYHKWPMKA-----ALLTPMRAWTTQLQKLKGRCMTVFGDTLLCS 3445
K Q + ++ + A L + W ++ + + +T+ GD LL S
Sbjct: 3292 E-----KIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS 3346
Query: 3446 AAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLAT 3504
A + Y+G F R EL+++ W+ + V IP N L
Sbjct: 3347 AFVSYVGYFTKKYRNELMEKFWIPYIHNLK------------------VPIPITNGL--- 3385
Query: 3505 HSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALI 3564
LSLL+ +++ W+ P + + +L + RWPL++D + +
Sbjct: 3386 ----DPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTE-----RWPLIVDAQLQGIK 3436
Query: 3565 WL 3566
W+
Sbjct: 3437 WI 3438
Score = 62.4 bits (150), Expect = 1e-08
Identities = 196/1003 (19%), Positives = 347/1003 (34%), Gaps = 145/1003 (14%)
Query: 3757 LEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFL 3816
LE+Q+L ++ +E P+LE +L + ++ E+ LL L + +
Sbjct: 3544 LEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3603
Query: 3817 RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCM 3876
N+ + ++ E + +++ YRP + L+ L + P++
Sbjct: 3604 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQF 3663
Query: 3877 SPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV--TALGLTQVPLV 3934
S + + V ++A+ P A+ + Q +LT ++ S TA GL + +
Sbjct: 3664 SLKAFNVVFEKAIQRTTP---------ANEVKQRVINLTDEITYSVYMYTARGLFERDKL 3714
Query: 3935 GALGALALLQATGKAS----ELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHEC 3990
L + + K EL+ L +P A S PV + W G KA E
Sbjct: 3715 IFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVS-----PVDFLQHQGWGGIKALSEM 3769
Query: 3991 EMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPE 4050
+ F L + + G + W+ + + P +L QKL + R LRP+
Sbjct: 3770 D------EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPD 3822
Query: 4051 CLAGALADFTTSLLGRPLDENTYAP-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQ 4109
+ A+ +F +G E + ++ S + + +L P P + L +
Sbjct: 3823 RMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG--K 3880
Query: 4110 KLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLD--------NCHLMP 4161
KL G+ + G E V + L A +GHW++L N HL+
Sbjct: 3881 KLGFTIDNGKLHNVSLGQGQEV-----VAENALDVAAEKGHWVILQVRGGQHCRNIHLVA 3935
Query: 4162 HWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLI---VPAESSAS 4218
W LG LD+ R + H D+R+++ P+ +
Sbjct: 3936 RW-----------LG------------TLDKKLERYSTGSHEDYRVFISAEPAPSPETHI 3972
Query: 4219 LP------AVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLL 4272
+P A+ + P + +L L L M+ L H ++
Sbjct: 3973 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVA 4032
Query: 4273 HRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTE 4331
R+ +G + ++ LT + + L A+ P ++ L + YGG + D
Sbjct: 4033 ERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDW 4092
Query: 4332 DREALISLTQACLSPSSGSWVQPHTPQS--LLATLMPLPELRELDAMAECKAQMHLLPSP 4389
DR L + L+ +++ + LLA +P LD + LP P
Sbjct: 4093 DRR----LCRTYLA----EYIRTEMLEGDVLLAPGFQIPP--NLDYKGYHEYIDENLP-P 4141
Query: 4390 PEPRLCGLSEGPQAWLLRRQSRALLSALQRSSP--------------------VWVPESR 4429
P L GL + L S L + P +P R
Sbjct: 4142 ESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSER 4201
Query: 4430 RGAQLAERR--LRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLET 4487
+G L RR QV L+ + + + E A + + P V
Sbjct: 4202 KGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAA-----EKTPYVVVAFQ 4256
Query: 4488 EALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQP 4547
E ++ L ++R L L LKG + ++ AL+ +P W A
Sbjct: 4257 ECERMNILTNEMRRSLKELNLGLKGELTI-TTDVEDLSTALFYDTVPDTWVARAYPSMMG 4315
Query: 4548 PWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVP 4607
W LL+R + A + L+ F +P+ L A+ +
Sbjct: 4316 LAAWY------ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAI-----MQSMAR 4364
Query: 4608 SSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIA 4667
+ +P + +S ++ K E + P P G + GL + A WD
Sbjct: 4365 KNEWPLDKMCLSVEVTKKNREDMTAP-------------PREGSYVYGLFMEGARWDTQT 4411
Query: 4668 GALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710
G + ++ + +P PV P + +Y CPVY
Sbjct: 4412 GVIAEARLKELTPAMPVIFIKAIP----VDRMETKNIYECPVY 4450
Score = 44.7 bits (104), Expect = 0.002
Identities = 70/406 (17%), Positives = 153/406 (37%), Gaps = 56/406 (13%)
Query: 1002 ETPVP----LPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLT 1057
E PVP L C R + + +W + V++ +I +WK + + E+ +
Sbjct: 1256 EVPVPDYKQLKACH-REVRLLKELWDMVVVVNTSIEDWKTTKWKDINV----EQMDIDCK 1310
Query: 1058 EAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSL---NCQCLLRALGLGS 1114
+ A+ +L+ + + ++ + L + L ++ + Q L++A +
Sbjct: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQV-K 1369
Query: 1115 LQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFIL 1174
+ E TL LL L + D + + + ++ ++ L W + +
Sbjct: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ------ 1423
Query: 1175 HVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKS 1234
H P+ +GT +L L ++++++ L ++ +
Sbjct: 1424 HEPHPR----------------------TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYL 1461
Query: 1235 GDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVM 1291
K W + +++ +W Q+ W L + +++ Q P + RF +
Sbjct: 1462 AHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGD--SQRFDDI 1519
Query: 1292 DDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYG 1351
+ +++ LM +V P V+ A P L L+A L +L L
Sbjct: 1520 NQEFKALMEDAVKTPNVV-----EATSKP-----GLYNKLEALKKSLAICEKALAEYLET 1569
Query: 1352 VCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397
FPR +F+S ++L+ +L+ + E + + F + + FR
Sbjct: 1570 KRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFR 1615
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 158 bits (399), Expect = 1e-37
Identities = 230/1062 (21%), Positives = 415/1062 (39%), Gaps = 161/1062 (15%)
Query: 1638 CWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRA 1695
C+ ++ Y+YEYLG PRL P L +R + L +L + G GP G GK
Sbjct: 1784 CFANICDAQIQYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLIMGGAPAGPAGTGKTE 1841
Query: 1696 IVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQR 1755
L +ALG + + CS Q++ + N G Q GAW ++ +++ +LS + +
Sbjct: 1842 TTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQ 1901
Query: 1756 LGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVP 1815
+ Q+A R +++G +++ GY A + +P
Sbjct: 1902 V--------KCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGY-------AGRAELP 1946
Query: 1816 ANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLP 1875
NL L RP A+ +PD + E+ L+ G +A +A + ++L +EL+S
Sbjct: 1947 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS-------- 1998
Query: 1876 LLKQILED----TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNL--- 1928
KQ D I+++ V K P + E+ L+R+ + + +L
Sbjct: 1999 --KQDHYDWGLRAIKSVLVVAGSLKRGDP---SRAEDQVLMRALRDFNIPKIVTDDLPVF 2053
Query: 1929 RGLLCALFPSASQVLAEPMTY-KLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASG 1987
GL+ LFP+ + + K++K +VE + L + + QL + L
Sbjct: 2054 MGLIGDLFPALDVPRKRDLNFEKIIKQSIVE----LKLQAEDSFVLKVVQLEELLQVRHS 2109
Query: 1988 ILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEG 2047
+ ++G AGSGK+ SL K L +PV + L P ++ E G +
Sbjct: 2110 VFIVGNAGSGKSQVLKSLNKTYQNLKR---------KPVAVD-LDPKAVTCDELFGIINP 2159
Query: 2048 SC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSEL 2105
W G+F ++R + G K WII DG + W++S+ ++ +
Sbjct: 2160 VTREWKDGLFSTIMRDLANITHDGPK-----------WIILDGDIDPMWIESLNTVMDDN 2208
Query: 2106 PQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCILSALMASL 2164
L+L S ++I L+ E++ +P V +++ + W ++S+ +
Sbjct: 2209 KVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWI--- 2265
Query: 2165 PYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARIL 2224
E R A L + + +P L L G + V E+T + IL
Sbjct: 2266 --ERRKVQSEKANLMILFDKYLPTCLDKLRF-GFKKI----------TPVPEITVIQTIL 2312
Query: 2225 HSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAV 2284
+ L L L E+ P PD RE L
Sbjct: 2313 YLLECL---LTEKTVP---------------------------------PDSPRE--LYE 2334
Query: 2285 SSFLFALIWGF-GAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDGTLV 2343
F+F W F GA + F + I+ + P +FD ++ P+ +
Sbjct: 2335 LYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTI-KFPSQGTIFDYYIDPDTKKFL 2393
Query: 2344 PFTGQYLSSHIKGTL---GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV 2400
P+T + S + + + + +T R+ Y +DLL+ PV+L G A TGKS +
Sbjct: 2394 PWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGD 2453
Query: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA 2460
+E + Y F+ +L ++ + + L++ ++D+++
Sbjct: 2454 KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMP 2513
Query: 2461 TSDPEKSCQPVLETLRQAMDGT-VYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLF 2519
D + P +RQ MD Y L L+ + ++A + P + RL
Sbjct: 2514 EVDKYGTVAP-HTLIRQHMDHRHWYDRHKLTLKDIH-NCQYVACMN-PTSGSFTIDSRLQ 2570
Query: 2520 RLFTVLALESMTQATLLERHVPIIQAWLERFPSVERE-RALARGLVRASVEAWEAVCNCF 2578
R F V A+ Q L + I+ L F SV + ++ LV A++ + + F
Sbjct: 2571 RHFCVFAVSFPGQEALTTIYNTILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATF 2629
Query: 2579 MPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMM 2638
+P+ + HY F+L +S++ GL + V+
Sbjct: 2630 LPTAIKFHYVFNLRDLSNIF----------------------------QGLLFSTAEVLK 2661
Query: 2639 ATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
++VRLWLHE +R + D++ +++ ++ + + F
Sbjct: 2662 TPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2703
Score = 119 bits (298), Expect = 7e-26
Identities = 157/722 (21%), Positives = 292/722 (40%), Gaps = 77/722 (10%)
Query: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDA 2930
H+ R+ R+L PR + LL+ G G+G+ + LA+ I F + I D
Sbjct: 2768 HICRINRILESPRGNALLV-GVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDL 2826
Query: 2931 SWH---AGMLSQP-VALLVPSGVD----LTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982
+ A + + P V L+ S V L ++ LLA SG PG + E +++ I +
Sbjct: 2827 AAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLA---SGEIPGLFMEDEVENIISSM 2883
Query: 2983 PRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042
+ + N +E + F ++V L + + ++ + F ++ +ID
Sbjct: 2884 RPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCT--AID 2941
Query: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102
+ W + AL V+ LE + +P + + + + + M+ ++L+ + +
Sbjct: 2942 WFHEWPEDALVSVSARFLEETEGIPWEVKA-SISFFMSYVHTTVNEMSRVYLATERRYNY 3000
Query: 3103 LCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIF 3162
TPKTFL+ + + L + ++ K +R++N L L+ + +
Sbjct: 3001 -------TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053
Query: 3163 DLEQQLKDSGKSLSMFQQQ--LEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAF 3220
E +LK +S Q +E K+ ++ + + +E +E + + Q E
Sbjct: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD--QEEVKVEVINKNVTEKQKACETD 3111
Query: 3221 LEQMSKAFL---EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FHHETGWA 3271
L + A L E L L + E++S+ +PP++VV VT A+ L + W
Sbjct: 3112 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWK 3171
Query: 3272 SAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWL 3330
+AK ++ D F L F KE I ++ L P D +R+ S AA L +W
Sbjct: 3172 AAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWC 3231
Query: 3331 WAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQA 3390
++ + +C P L++ A L Q +L + + E + L E A A
Sbjct: 3232 INIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATA 3291
Query: 3391 SHNCVAKTLSQAQCGQYHKWPMKA-----ALLTPMRAWTTQLQKLKGRCMTVFGDTLLCS 3445
K Q + ++ + A L + W ++ + + +T+ GD LL S
Sbjct: 3292 E-----KIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS 3346
Query: 3446 AAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLAT 3504
A + Y+G F R EL+++ W+ + V IP N L
Sbjct: 3347 AFVSYVGYFTKKYRNELMEKFWIPYIHNLK------------------VPIPITNGL--- 3385
Query: 3505 HSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALI 3564
LSLL+ +++ W+ P + + +L + RWPL++D + +
Sbjct: 3386 ----DPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTE-----RWPLIVDAQLQGIK 3436
Query: 3565 WL 3566
W+
Sbjct: 3437 WI 3438
Score = 60.5 bits (145), Expect = 4e-08
Identities = 195/1003 (19%), Positives = 346/1003 (34%), Gaps = 145/1003 (14%)
Query: 3757 LEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFL 3816
LE+Q+L ++ +E P+LE +L + ++ E+ LL L + +
Sbjct: 3544 LEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3603
Query: 3817 RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCM 3876
N+ + ++ E + +++ YRP + L+ L + P++
Sbjct: 3604 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQF 3663
Query: 3877 SPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV--TALGLTQVPLV 3934
S + + V ++A+ P A+ + Q +LT ++ S TA GL + +
Sbjct: 3664 SLKAFNVVFEKAIQRTTP---------ANEVKQRVINLTDEITYSVYMYTARGLFERDKL 3714
Query: 3935 GALGALALLQATGKAS----ELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHEC 3990
L + + K EL+ L +P A S PV + W G KA E
Sbjct: 3715 IFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVS-----PVDFLQHQGWGGIKALSEM 3769
Query: 3991 EMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPE 4050
+ F L + + G + W+ + + P +L QKL + R LRP+
Sbjct: 3770 D------EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPD 3822
Query: 4051 CLAGALADFTTSLLGRPLDENTYAP-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQ 4109
+ A+ +F +G E + ++ S + + +L P P + L +
Sbjct: 3823 RMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG--K 3880
Query: 4110 KLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLD--------NCHLMP 4161
KL G+ + G E V + L A +GHW++L N HL+
Sbjct: 3881 KLGFTIDNGKLHNVSLGQGQEV-----VAENALDVAAEKGHWVILQVRGGQHCRNIHLVA 3935
Query: 4162 HWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLI---VPAESSAS 4218
W LG LD+ + H D+R+++ P+ +
Sbjct: 3936 RW-----------LG------------TLDKKLEHYSTGSHEDYRVFISAEPAPSPETHI 3972
Query: 4219 LP------AVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLL 4272
+P A+ + P + +L L L M+ L H ++
Sbjct: 3973 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVA 4032
Query: 4273 HRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTE 4331
R+ +G + ++ LT + + L A+ P ++ L + YGG + D
Sbjct: 4033 ERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDW 4092
Query: 4332 DREALISLTQACLSPSSGSWVQPHTPQS--LLATLMPLPELRELDAMAECKAQMHLLPSP 4389
DR L + L+ +++ + LLA +P LD + LP P
Sbjct: 4093 DRR----LCRTYLA----EYIRTEMLEGDVLLAPGFQIPP--NLDYKGYHEYIDENLP-P 4141
Query: 4390 PEPRLCGLSEGPQAWLLRRQSRALLSALQRSSP--------------------VWVPESR 4429
P L GL + L S L + P +P R
Sbjct: 4142 ESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSER 4201
Query: 4430 RGAQLAERR--LRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLET 4487
+G L RR QV L+ + + + E A + + P V
Sbjct: 4202 KGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAA-----EKTPYVVVAFQ 4256
Query: 4488 EALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQP 4547
E ++ L ++R L L LKG + ++ AL+ +P W A
Sbjct: 4257 ECERMNILTNEMRRSLKELNLGLKGELTI-TTDVEDLSTALFYDTVPDTWVARAYPSMMG 4315
Query: 4548 PWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVP 4607
W LL+R + A + L+ F +P+ L A+ +
Sbjct: 4316 LAAWY------ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAI-----MQSMAR 4364
Query: 4608 SSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIA 4667
+ +P + +S ++ K E + P P G + GL + A WD
Sbjct: 4365 KNEWPLDKMCLSVEVTKKNREDMTAP-------------PREGSYVYGLFMEGARWDTQT 4411
Query: 4668 GALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710
G + ++ + +P PV P + +Y CPVY
Sbjct: 4412 GVIAEARLKELTPAMPVIFIKAIP----VDRMETKNIYECPVY 4450
Score = 44.7 bits (104), Expect = 0.002
Identities = 70/406 (17%), Positives = 153/406 (37%), Gaps = 56/406 (13%)
Query: 1002 ETPVP----LPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLT 1057
E PVP L C R + + +W + V++ +I +WK + + E+ +
Sbjct: 1256 EVPVPDYKQLKACH-REVRLLKELWDMVVVVNTSIEDWKTTKWKDINV----EQMDIDCK 1310
Query: 1058 EAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSL---NCQCLLRALGLGS 1114
+ A+ +L+ + + ++ + L + L ++ + Q L++A +
Sbjct: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQV-K 1369
Query: 1115 LQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFIL 1174
+ E TL LL L + D + + + ++ ++ L W + +
Sbjct: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ------ 1423
Query: 1175 HVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKS 1234
H P+ +GT +L L ++++++ L ++ +
Sbjct: 1424 HEPHPR----------------------TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYL 1461
Query: 1235 GDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVM 1291
K W + +++ +W Q+ W L + +++ Q P + RF +
Sbjct: 1462 AHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGD--SQRFDDI 1519
Query: 1292 DDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYG 1351
+ +++ LM +V P V+ A P L L+A L +L L
Sbjct: 1520 NQEFKALMEDAVKTPNVV-----EATSKP-----GLYNKLEALKKSLAICEKALAEYLET 1569
Query: 1352 VCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397
FPR +F+S ++L+ +L+ + E + + F + + FR
Sbjct: 1570 KRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFR 1615
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 87.0 bits (214), Expect = 4e-16
Identities = 186/886 (20%), Positives = 322/886 (36%), Gaps = 132/886 (14%)
Query: 3864 LSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV 3923
++ L + P++ S + + V ++A++ P E L + L +T + T+
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAP-----DESLRERVANLIDSITFSVYQYTI 55
Query: 3924 TALGLTQVPLVGALGALA----LLQATGKASELERLALWPGLAASPSTVHSKPVSDVARP 3979
GL + + L L L+ A EL+ L P + S V
Sbjct: 56 R--GLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVE---------- 103
Query: 3980 AWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQ 4039
+L +AW ++L + F L + G + +W+ ++ P +L Q
Sbjct: 104 -FLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTAL-Q 161
Query: 4040 KLILWRVLRPECLAGALADFTTSLLG------RPLDENTYAPTMPFKHSQATQPMLILLP 4093
+L + R +RP+ + AL DF LG R LD T F+ S PM +L
Sbjct: 162 RLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFAT-----SFEESGPATPMFFILS 216
Query: 4094 PPGHPSATLHPLTVIQKLAAK--YQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHW 4151
P + PL ++ K Y + ++LG V + L A +GHW
Sbjct: 217 PG------VDPLKDVESQGRKLGYTFNNQNFHNVSLGQ---GQEVVAEAALDLAAKKGHW 267
Query: 4152 LVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLIV 4211
++L N HL+ W L E+ L++ + H +FR+++
Sbjct: 268 VILQNIHLVAKWLSTL-------------------EKKLEEHSENS----HPEFRVFMSA 304
Query: 4212 ---PAESSASLPAVLTQHSMPV--------FWNQSLELGHVLIDSVELAQQVLYMQPPTQ 4260
P+ +P + ++S+ + N L + D++E+ + +
Sbjct: 305 EPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILF 364
Query: 4261 ALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAA 4319
AL H ++ R+ +G + ++ LT V + L A+ P ++ L
Sbjct: 365 AL--CYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFG 422
Query: 4320 SVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAEC 4379
+ YGG + D DR L + L G +++P + L+ P +D
Sbjct: 423 EIMYGGHITDDWDRR----LCRTYL----GEFIRPEMLEGELSLAPGFPLPGNMDYNGYH 474
Query: 4380 KAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRL 4439
+ LP P P L GL + L + S L + P R +Q +
Sbjct: 475 QYIDAELP-PESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQP-------RDSQARDGAG 526
Query: 4440 RQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTL 4499
R +V LE + + +T DE + P + R P V E ++ L +
Sbjct: 527 ATREEKVKALLEEILERVT-----DEFNIPELMAKVEERTPYIVVAFQECGRMNILTREI 581
Query: 4500 QRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRG 4559
QR L L LKG S + +AL+ +P W A W L R
Sbjct: 582 QRSLRELELGLKGELTMTSHM-ENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRI 640
Query: 4560 QLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVS 4619
+ L + G +P V+ L+ F +P+ L A+ + + +P + ++
Sbjct: 641 KELEAWTG-----DFTMPSTVW-LTGFFNPQSFLTAI-----MQSTARKNEWPLDQMALQ 689
Query: 4620 SQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPS 4679
+ K E +P P G + GL + A WD AG + ++ +
Sbjct: 690 CDMTKKNREEFRSP-------------PREGAYIHGLFMEGACWDTQAGIITEAKLKDLT 736
Query: 4680 PLPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSRNI 4725
P PV P +VYSCPVY G + + N+
Sbjct: 737 PPMPVMFIKAIPADKQ----DCRSVYSCPVYKTSQRGPTYVWTFNL 778
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 55.8 bits (133), Expect = 1e-06
Identities = 26/79 (32%), Positives = 45/79 (56%)
Query: 3572 EENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQE 3631
E ++ P E QK + ++E++E EE E ED+ +E++ EE + E+E
Sbjct: 230 ERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE 289
Query: 3632 KEQEENEEKEEEKTESQGS 3650
+E+EE EE+EEE+ E + +
Sbjct: 290 EEEEEEEEEEEEEEEEEAA 308
Score = 53.5 bits (127), Expect = 5e-06
Identities = 23/51 (45%), Positives = 36/51 (70%)
Query: 3603 EEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPA 3653
EE+DE EE E E++ E++ EE + E+E+E+EE EE+EEE+ E + + A
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 50.4 bits (119), Expect = 4e-05
Identities = 24/62 (38%), Positives = 41/62 (66%), Gaps = 2/62 (3%)
Query: 3592 NQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSK 3651
+ K++ +EED+E EE E E++ +E+ EE + E+E+E+EE EE+EEE+ E + +
Sbjct: 248 SSKQKGILSHEEEDEEEEEEEEEEEEDEEE--EEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Query: 3652 PA 3653
A
Sbjct: 306 EA 307
Score = 49.3 bits (116), Expect = 9e-05
Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Query: 3566 LDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEE 3625
L P LE+ S + +G +++ E + + +EED+E EE E E++ +E++ EE
Sbjct: 235 LCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294
Query: 3626 RKNEQEKEQEENEEKE---EEKTESQGSKPAYETQLPSLP 3662
+ E+E+E+EE + +E T ++ A E + P P
Sbjct: 295 EEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESP 334
Score = 40.0 bits (92), Expect = 0.055
Identities = 21/45 (46%), Positives = 25/45 (55%)
Query: 2688 HLGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
H +D +E EEEEEEE E E E E + E+ E EEEEE
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301
Score = 38.5 bits (88), Expect = 0.16
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 3593 QKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKE-----QEENEEKEEEKT-- 3645
++ E + + +EE++E EE E E++ +E++ EE + E+E QE+ +K
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
Query: 3646 ----ESQGSKPAY 3654
ES KP Y
Sbjct: 328 LRGPESPSPKPEY 340
Score = 37.0 bits (84), Expect = 0.47
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 2689 LGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
L + ++ EEEEEEE E E E E + E+ E EEEEE
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Score = 36.6 bits (83), Expect = 0.61
Identities = 20/62 (32%), Positives = 30/62 (48%)
Query: 3596 ESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYE 3655
E D+ + E S E+ Q EE E+E+E+EE EE EEE+ E + + E
Sbjct: 230 ERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE 289
Query: 3656 TQ 3657
+
Sbjct: 290 EE 291
Score = 36.6 bits (83), Expect = 0.61
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 2691 KDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
++ +E EEEEEE+ E E E E + E+ E EEEEE
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
Score = 36.6 bits (83), Expect = 0.61
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 2691 KDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
++ +E EEEEE+E E E E E + E+ E EEEEE
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 36.6 bits (83), Expect = 0.61
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 2691 KDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
++ +E EEEE+EE E E E E + E+ E EEEEE
Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 36.6 bits (83), Expect = 0.61
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 2691 KDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
++ +E EEE+EEE E E E E + E+ E EEEEE
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 35.0 bits (79), Expect = 1.8
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 2691 KDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEP---YGLQVARVSNSRDP 2747
++ +E E+EEEEE E E E E + E+ E EEE P + + S + P
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326
Query: 2748 SLTPSIGPVSRGMKESIS 2765
L GP S K S
Sbjct: 327 ELR---GPESPSPKPEYS 341
Score = 34.7 bits (78), Expect = 2.3
Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
Query: 3580 ALTEGRGKGL-MRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEER---KNEQEKEQE 3635
A +E KGL ++ + E ++ E + ED E+ ++++ +E+E E+E
Sbjct: 205 AASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEE 264
Query: 3636 ENEEKEEEKTESQGSKPAYETQ 3657
E EE+EEE+ E + + E +
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEE 286
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 52.0 bits (123), Expect = 1e-05
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 3553 PLLLDPSNEALIWLDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESN 3612
PL+L P AL P + P+L + L +++ + + K++ E ++
Sbjct: 653 PLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKK 712
Query: 3613 EAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPSLPYLSVLSGA 3670
E E + KE++ E+ K E+EK ++E E+ + EK + + P P +P L++ GA
Sbjct: 713 EKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVE---PVALAPSPVIPRLTLRVGA 767
Score = 36.2 bits (82), Expect = 0.80
Identities = 29/134 (21%), Positives = 58/134 (43%), Gaps = 11/134 (8%)
Query: 3506 SPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIW 3565
+P + SS + D ++ + A L G P ++ P + P+ E L
Sbjct: 449 TPLPLSGGTSSSDNSWTMDASIDEVVRKAKL-GTPSNMPPNFPYISSPSVSPPTPEPLH- 506
Query: 3566 LDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEE 3625
+ E ++ P+ E + K K+E KT MK+++ + + E + + K ++
Sbjct: 507 ----KVYEEKTKLPSSVEVKKK-----LKKELKTKMKKKEKQRDREREKDKNKDKSKEKD 557
Query: 3626 RKNEQEKEQEENEE 3639
+ E+EK++E E
Sbjct: 558 KVKEKEKDKETGRE 571
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 51.2 bits (121), Expect = 2e-05
Identities = 23/62 (37%), Positives = 38/62 (61%)
Query: 3603 EEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPSLP 3662
EE++E E E E++ +E + EE K E+++E EE EEKE +K E + + +T++
Sbjct: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
Query: 3663 YL 3664
YL
Sbjct: 184 YL 185
Score = 48.9 bits (115), Expect = 1e-04
Identities = 20/65 (30%), Positives = 42/65 (64%)
Query: 3593 QKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKP 3652
++ E + + +E ++E +E + ED+ +E+K EE++ ++E+E++E ++ EEEK E +
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
Query: 3653 AYETQ 3657
TQ
Sbjct: 179 IQRTQ 183
Score = 44.7 bits (104), Expect = 0.002
Identities = 21/71 (29%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Query: 3585 RGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKE-QEENEEKEEE 3643
+G + + E + +++EE+ E E+ + E++ KE++ EE + E+EKE ++ EEK EE
Sbjct: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
Query: 3644 KTESQGSKPAY 3654
+ +++ + Y
Sbjct: 174 EIDTEIQRTQY 184
Score = 35.8 bits (81), Expect = 1.0
Identities = 14/45 (31%), Positives = 31/45 (68%)
Query: 3604 EDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQ 3648
E+ +++ E++ E++ EE + E+++E++E +E+EEEK E +
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152
Score = 35.8 bits (81), Expect = 1.0
Identities = 17/60 (28%), Positives = 35/60 (58%)
Query: 3615 EDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPSLPYLSVLSGADPEL 3674
E++ +E++ E + E+E+E+EE+EE+EE++ E + + E + + V D E+
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179
Score = 35.0 bits (79), Expect = 1.8
Identities = 18/39 (46%), Positives = 22/39 (56%)
Query: 2694 QESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
+E E EEEEE V E E E E + E+ E EE+EE
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEE 157
Score = 34.7 bits (78), Expect = 2.3
Identities = 21/93 (22%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 3565 WLDPLPLEENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAE 3624
W LP++++ + A G+ N+ ++T ++ S + ++ + ++ E
Sbjct: 69 WAVGLPVKDS-GVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEE 127
Query: 3625 ERKNEQEKEQEENEEKEEEKTESQGSKPAYETQ 3657
E E+EKE+E+ E++EEE+ E + + E +
Sbjct: 128 EEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160
Score = 33.5 bits (75), Expect = 5.2
Identities = 19/46 (41%), Positives = 24/46 (52%)
Query: 2687 QHLGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEE 2732
Q L + +E EEEEEE E E E E + E+ E +EEEE
Sbjct: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEE 159
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 51.2 bits (121), Expect = 2e-05
Identities = 21/50 (42%), Positives = 35/50 (70%)
Query: 3604 EDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPA 3653
+D++ EE E E++ +E + EE ++E+E+E+EE EE+EE + QG K A
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSA 408
Score = 44.3 bits (103), Expect = 0.003
Identities = 27/65 (41%), Positives = 38/65 (58%), Gaps = 3/65 (4%)
Query: 3605 DDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQLPSLPYL 3664
DDE EE E E + +E++AEE E+E E+EE EE+EEE+ E Q ++ PS L
Sbjct: 359 DDEDEEEEE-EGEEEEEEAEEE--EEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKIL 415
Query: 3665 SVLSG 3669
+G
Sbjct: 416 DPNTG 420
Score = 43.5 bits (101), Expect = 0.005
Identities = 18/46 (39%), Positives = 32/46 (69%)
Query: 3612 NEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQ 3657
++ ED+ +E++ EE + E E+E+EE+EE+EEE+ E + +P Q
Sbjct: 358 SDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQ 403
Score = 42.7 bits (99), Expect = 0.009
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 3600 DMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSK 3651
D +EE++ EE EAE++ +E + EE + E+E+E+E + + EK+ + K
Sbjct: 362 DEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRK 413
Score = 35.8 bits (81), Expect = 1.0
Identities = 28/69 (40%), Positives = 32/69 (46%), Gaps = 8/69 (11%)
Query: 2689 LGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRDPS 2748
L D E EEEE EE E E E E + E+ E EEEEEP Q + S PS
Sbjct: 357 LSDDEDEEEEEEGEEEEEEAEEEEEEDEEEE---EEEEEEEEEEPQ--QRGQGEKSATPS 411
Query: 2749 ---LTPSIG 2754
L P+ G
Sbjct: 412 RKILDPNTG 420
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 123
Score = 50.8 bits (120), Expect = 3e-05
Identities = 21/66 (31%), Positives = 44/66 (66%)
Query: 3583 EGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEE 3642
E GK + +++ + + K++ E+E+ E E++ K++K + +K ++E+E+EE EE+EE
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83
Query: 3643 EKTESQ 3648
E+ E +
Sbjct: 84 EEKEEE 89
Score = 50.8 bits (120), Expect = 3e-05
Identities = 20/66 (30%), Positives = 44/66 (66%)
Query: 3583 EGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEE 3642
EG+ K + +++E + K ++ E + E E++ +++K +++K E+E+E+EE EE+EE
Sbjct: 26 EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE 85
Query: 3643 EKTESQ 3648
++ E +
Sbjct: 86 KEEEEK 91
Score = 49.3 bits (116), Expect = 9e-05
Identities = 20/58 (34%), Positives = 40/58 (68%)
Query: 3591 RNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQ 3648
+ +K++ +T+ EE +E+EE E E + KE++ E+RK +++K++ + EK +EK E +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Score = 47.4 bits (111), Expect = 3e-04
Identities = 20/54 (37%), Positives = 37/54 (68%)
Query: 3591 RNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEK 3644
+ +KR+ K +EE+ E EE E E++ +E+K E R+ +++K++ EE+EE+K
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Score = 47.0 bits (110), Expect = 5e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Query: 3591 RNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGS 3650
+ +K+++K K ++ E EE + K+++ EER+ E+E+E+EE EE+E+E+ +
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Query: 3651 K 3651
K
Sbjct: 100 K 100
Score = 45.4 bits (106), Expect = 0.001
Identities = 21/61 (34%), Positives = 39/61 (63%), Gaps = 3/61 (4%)
Query: 3591 RNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGS 3650
R +KR+ K KEE++ EE E E++ +E++ EE + ++K++ +E+EEEK + +
Sbjct: 62 RKRKRKKK---KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 3651 K 3651
K
Sbjct: 119 K 119
Score = 43.5 bits (101), Expect = 0.005
Identities = 16/66 (24%), Positives = 43/66 (65%)
Query: 3583 EGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEE 3642
E K R +K++ + + +EE++E EE + E++ +E + ++K ++ +++EE E+K++
Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Query: 3643 EKTESQ 3648
+ +++
Sbjct: 116 RRRKTK 121
Score = 39.7 bits (91), Expect = 0.072
Identities = 16/67 (23%), Positives = 38/67 (56%)
Query: 3591 RNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGS 3650
+ ++ E + + +EE+ + + + + + +E++ EE + E+EKE+EE EE K + +
Sbjct: 45 KTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Query: 3651 KPAYETQ 3657
+ E +
Sbjct: 105 RKEEEEE 111
Score = 38.9 bits (89), Expect = 0.12
Identities = 16/56 (28%), Positives = 36/56 (64%)
Query: 3602 KEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKPAYETQ 3657
K++ E+EE+ E E+ +E++ E ++ E+ KE+ + +EK+++ E++ K E +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Score = 38.9 bits (89), Expect = 0.12
Identities = 19/69 (27%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
Query: 3583 EGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEE 3642
E R + + + +E++ ++E++E + + + + +E++ EE + E+E+E+EE EEKEE
Sbjct: 35 EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE-EEKEE 93
Query: 3643 EKTESQGSK 3651
+ + K
Sbjct: 94 GRRRKKKKK 102
Score = 38.1 bits (87), Expect = 0.21
Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 21/79 (26%)
Query: 3591 RNQKRESKTDMKEEDDESE---------------------ESNEAEDQTKEQKAEERKNE 3629
+ + +T+ EE++E E E+ + +++ +E+K +RK +
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67
Query: 3630 QEKEQEENEEKEEEKTESQ 3648
++KE+EE EE+EEE+ E +
Sbjct: 68 KKKEEEEREEEEEEEEEEK 86
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.4 bits (119), Expect = 4e-05
Identities = 54/208 (25%), Positives = 97/208 (46%), Gaps = 35/208 (16%)
Query: 3593 QKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQGSKP 3652
+K+ES + +EE+ E EE E E+ +E+ EERK E+E E+++ E++EEEK + + K
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEE--EERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 3653 AYETQLPSLPY---LSVLSGADPE-LGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQR 3708
E Q + ++S + E L + +E +C L + E + +E Q+ LQ
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDR-EKEILKKEKQFKLQE 2354
Query: 3709 EQLSPPQVQPGFCLYLSTTLSLCAMEKVLGCELLKGL-----NVLDLGLNMEILEEQMLH 3763
++ SL E+VL +L+G+ + LG+ L++ M
Sbjct: 2355 QRRK----------------SLRGRERVL--SILRGVPHGKGRAIRLGVLKSPLKKLMST 2396
Query: 3764 EILCRE-----YPELETRWQDLKIRALD 3786
+ +E PE + W+D K ++
Sbjct: 2397 ALEMKEKTPVPVPEKQISWEDKKATVVE 2424
Score = 42.0 bits (97), Expect = 0.015
Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 3596 ESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEE-NEEKEEEKTESQGSKPAY 3654
ES+ EE + + E ++ ++ EER+ E+E+E+EE EE+EE K E +G +
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 3655 ETQ 3657
E +
Sbjct: 2281 EKE 2283
Score = 40.8 bits (94), Expect = 0.032
Identities = 18/57 (31%), Positives = 34/57 (59%)
Query: 3592 NQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTESQ 3648
+++ ES D E+ + E E + +E++ EE E+E+E++E EE EE++ E +
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE 2283
Score = 38.1 bits (87), Expect = 0.21
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 3587 KGLMRNQKRESKTDMKEEDDE-SEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKT 3645
+G +K S+ D E ++ SEE D+ ++Q++ + E+E+E+EE E+EE +
Sbjct: 2205 RGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVRE 2264
Query: 3646 ESQGSKPAYE 3655
E + K E
Sbjct: 2265 EEEERKEEEE 2274
Score = 38.1 bits (87), Expect = 0.21
Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 4/76 (5%)
Query: 3571 LEENRSFAPALTEGRGKGLMRNQK--RESKTDMKEEDDESEESNEAEDQTKEQKAEERKN 3628
LE+ S + E R + R ++ RE + + KEE++ E+ E E++ K++K +E+K
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Query: 3629 EQEKEQEENEEKEEEK 3644
E+ +E+EE EE++
Sbjct: 2297 EEVQEKEE--VFEEKE 2310
Score = 33.9 bits (76), Expect = 4.0
Identities = 18/60 (30%), Positives = 33/60 (55%)
Query: 3587 KGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEKTE 3646
K R K + K + ++ ESEE E ++ + E++++ +E+EE EE+EE + E
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 49.3 bits (116), Expect = 9e-05
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 4/89 (4%)
Query: 3583 EGRGKGLMRNQKRESKTDMKEEDD----ESEESNEAEDQTKEQKAEERKNEQEKEQEENE 3638
E + L E+K D K +D + +S E E++ +EQ+ EE + EQE+E+EE E
Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886
Query: 3639 EKEEEKTESQGSKPAYETQLPSLPYLSVL 3667
E+EE+ E S ET+ YL +L
Sbjct: 887 EEEEKGNEEPLSLDWPETRQKQAIYLFLL 915
Score = 38.5 bits (88), Expect = 0.16
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 26/102 (25%)
Query: 3582 TEGRGKGLMRNQKRESKTDMKEED-------DESEESNEAEDQTKEQKAE---ERKN--- 3628
T+G+G+ + E K D + ED D + NE E +++E AE E KN
Sbjct: 787 TQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEK 846
Query: 3629 -------------EQEKEQEENEEKEEEKTESQGSKPAYETQ 3657
E+E+E+EE +E+EEE+ E + + E +
Sbjct: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE 888
Score = 38.1 bits (87), Expect = 0.21
Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 14/91 (15%)
Query: 3572 EENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDE---SEESNEAEDQTK--------- 3619
+EN + EG +G + + E K + E + + +E EA++ K
Sbjct: 796 DENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSD 855
Query: 3620 --EQKAEERKNEQEKEQEENEEKEEEKTESQ 3648
+ + EE + E+++E+EE EE+EEE+ E +
Sbjct: 856 GGDSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886
Score = 38.1 bits (87), Expect = 0.21
Identities = 17/61 (27%), Positives = 34/61 (55%)
Query: 3580 ALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEE 3639
A G K + + +D + ++E EE E E++ +E++ EE + E+E+E+E+ E
Sbjct: 835 AENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNE 894
Query: 3640 K 3640
+
Sbjct: 895 E 895
Score = 37.0 bits (84), Expect = 0.47
Identities = 20/47 (42%), Positives = 24/47 (51%)
Query: 2690 GKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGL 2736
G D +SEEEEEEE E E E E + E+ E + EEP L
Sbjct: 853 GSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSL 899
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/71 (38%), Positives = 45/71 (63%), Gaps = 9/71 (12%)
Query: 3592 NQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERK-------NEQEKEQEENEEKEEEK 3644
+ +RES T +EED++SE+ E ED+ E+ EE++ E+E+E+EE EE+E E+
Sbjct: 1006 SDERESLT--REEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEE 1063
Query: 3645 TESQGSKPAYE 3655
E++G + E
Sbjct: 1064 AENEGEEAKTE 1074
Score = 45.1 bits (105), Expect = 0.002
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 3587 KGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEK-----E 3641
+ L R + +S+ + +EED E EE E ++ K Q EE + E+E+ +EE E+ E
Sbjct: 1010 ESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGE 1069
Query: 3642 EEKTESQGSKPAYETQLPSL 3661
E KTE E+Q SL
Sbjct: 1070 EAKTEGLMKDDRAESQASSL 1089
Score = 34.3 bits (77), Expect = 3.0
Identities = 22/79 (27%), Positives = 34/79 (43%)
Query: 2687 QHLGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRD 2746
+ L ++ E E+EEEE E+E E + E E EEEEE +V N +
Sbjct: 1010 ESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGE 1069
Query: 2747 PSLTPSIGPVSRGMKESIS 2765
+ T + R ++ S
Sbjct: 1070 EAKTEGLMKDDRAESQASS 1088
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/71 (38%), Positives = 45/71 (63%), Gaps = 9/71 (12%)
Query: 3592 NQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERK-------NEQEKEQEENEEKEEEK 3644
+ +RES T +EED++SE+ E ED+ E+ EE++ E+E+E+EE EE+E E+
Sbjct: 1022 SDERESLT--REEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEE 1079
Query: 3645 TESQGSKPAYE 3655
E++G + E
Sbjct: 1080 AENEGEEAKTE 1090
Score = 45.1 bits (105), Expect = 0.002
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 3587 KGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEK-----E 3641
+ L R + +S+ + +EED E EE E ++ K Q EE + E+E+ +EE E+ E
Sbjct: 1026 ESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGE 1085
Query: 3642 EEKTESQGSKPAYETQLPSL 3661
E KTE E+Q SL
Sbjct: 1086 EAKTEGLMKDDRAESQASSL 1105
Score = 34.3 bits (77), Expect = 3.0
Identities = 22/79 (27%), Positives = 34/79 (43%)
Query: 2687 QHLGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRD 2746
+ L ++ E E+EEEE E+E E + E E EEEEE +V N +
Sbjct: 1026 ESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGE 1085
Query: 2747 PSLTPSIGPVSRGMKESIS 2765
+ T + R ++ S
Sbjct: 1086 EAKTEGLMKDDRAESQASS 1104
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/86 (31%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Query: 3569 LPLEENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKN 3628
L N +PA + + K L + R + + + S+ES+E E++ ++++ EE +
Sbjct: 1026 LSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEE 1085
Query: 3629 EQEKEQEENEEKEEEKTES--QGSKP 3652
E+E+++EE EE+EEE+ E Q S P
Sbjct: 1086 EEEEDEEEEEEEEEEEEEENIQSSPP 1111
Score = 39.3 bits (90), Expect = 0.094
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 21/99 (21%)
Query: 3569 LPLEENRS------FAPALTEGRGK--GLMRNQKRESKTDMKEEDDESEESNEAE----- 3615
LP EENR +P + G L++ ++ E + + +EE++E EE E E
Sbjct: 1319 LPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNV 1378
Query: 3616 ----DQTKEQKAEERKNEQEKEQ----EENEEKEEEKTE 3646
D K Q+ EE + EKE +++EE+EEE E
Sbjct: 1379 EKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417
Score = 35.4 bits (80), Expect = 1.4
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 11/82 (13%)
Query: 2694 QESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRDPSLTPSI 2753
+ES EEEEEE E E E E + E+ E EEEEE +Q S P LT
Sbjct: 1066 KESSEEEEEEEDEEEEEEEE--EEEEDEEEEEEEEEEEEEENIQ------SSPPRLTK-- 1115
Query: 2754 GPVSRGMKESISHKIRQEKGTR 2775
P S +K +++++G +
Sbjct: 1116 -PQSVAIKRKRPFVLKKKRGRK 1136
Score = 34.7 bits (78), Expect = 2.3
Identities = 16/59 (27%), Positives = 30/59 (50%)
Query: 3586 GKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEEEK 3644
G+ L+ ++ + + + ED + + EE + E+E+E+EE EE EEE+
Sbjct: 1315 GEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE 1373
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 194,091,537
Number of Sequences: 37866
Number of extensions: 9523678
Number of successful extensions: 77711
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 474
Number of HSP's successfully gapped in prelim test: 339
Number of HSP's that attempted gapping in prelim test: 50160
Number of HSP's gapped (non-prelim): 19296
length of query: 4753
length of database: 18,247,518
effective HSP length: 124
effective length of query: 4629
effective length of database: 13,552,134
effective search space: 62732828286
effective search space used: 62732828286
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.