Search of human proteins with 222080095

Search of human proteins with 222080095

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222080095 orexin receptor 1 [Homo sapiens]
         (425 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222080095 orexin receptor 1 [Homo sapiens]                         859   0.0  
gi|222080109 orexin receptor 2 [Homo sapiens]                         563   e-160
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]                 193   3e-49
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]       187   2e-47
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]      187   2e-47
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]      187   2e-47
gi|4758474 G protein-coupled receptor 10 [Homo sapiens]               159   6e-39
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]            157   2e-38
gi|4502607 cholecystokinin A receptor [Homo sapiens]                  156   3e-38
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]                  156   3e-38
gi|7669548 tachykinin receptor 3 [Homo sapiens]                       150   3e-36
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]          149   6e-36
gi|223633971 G protein-coupled receptor 83 [Homo sapiens]             147   2e-35
gi|157426873 tachykinin receptor 2 [Homo sapiens]                     144   2e-34
gi|62865887 G protein-coupled receptor 54 [Homo sapiens]              144   2e-34
gi|28875799 cholecystokinin B receptor [Homo sapiens]                 144   2e-34
gi|167000885 galanin receptor 1 [Homo sapiens]                        142   4e-34
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]          135   5e-32
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec...   135   5e-32
gi|4503905 galanin receptor 2 [Homo sapiens]                          134   2e-31
gi|161484640 neuromedin B receptor [Homo sapiens]                     133   3e-31
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]      132   6e-31
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]         130   2e-30
gi|4502455 bombesin-like receptor 3 [Homo sapiens]                    130   2e-30
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]                  129   4e-30
gi|20373179 G protein-coupled receptor 73 [Homo sapiens]              129   4e-30
gi|4557265 beta-1-adrenergic receptor [Homo sapiens]                  129   7e-30
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]         125   6e-29
gi|21426829 prokineticin receptor 2 [Homo sapiens]                    124   2e-28
gi|4505513 opiate receptor-like 1 [Homo sapiens]                      124   2e-28

>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score =  859 bits (2219), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA 60
           MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
Sbjct: 1   MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA 60

Query: 61  LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK 120
           LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
Sbjct: 61  LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK 120

Query: 121 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA 180
           VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
Sbjct: 121 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA 180

Query: 181 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR 240
           AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
Sbjct: 181 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR 240

Query: 241 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML 300
           KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
Sbjct: 241 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML 300

Query: 301 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF 360
           MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
Sbjct: 301 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF 360

Query: 361 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV 420
           LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
Sbjct: 361 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV 420

Query: 421 TTVLP 425
           TTVLP
Sbjct: 421 TTVLP 425


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score =  563 bits (1450), Expect = e-160
 Identities = 284/413 (68%), Positives = 334/413 (80%), Gaps = 10/413 (2%)

Query: 17  SREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNH 75
           ++EP   P DY+DE FLRYLWR+YL+PK+YEWVLIA Y+ VFVVAL+GN LVC+AVW+NH
Sbjct: 24  TQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNH 83

Query: 76  HMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVL 135
           HMRTVTNYFIVNLSLADVLVT  CLPA+L+VDITE+W FG +LCKVIPYLQ VSVSV+VL
Sbjct: 84  HMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVL 143

Query: 136 TLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANR 195
           TLS IALDRWYAICHPL+FKSTA+RAR SI+ IW VS  IM+PQA VMECS+V P LAN+
Sbjct: 144 TLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANK 203

Query: 196 TRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALV 255
           T LF+VCDERW  ++YPK+YH CFF+VTY+APL LM +AY QIFRKLW RQIPGT+S + 
Sbjct: 204 TTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQ 263

Query: 256 RNWK--RPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLP 313
           R WK  +P  Q     +G     + R  A  AE+KQ+RARRKTA+MLM+VLLVFA+CYLP
Sbjct: 264 RKWKPLQPVSQ----PRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLP 319

Query: 314 ISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
           IS+LNVLKRVFGMF    DRE VYA FTFSHWLVYANSAANPIIYNFLSGKFRE+FKAAF
Sbjct: 320 ISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAF 379

Query: 374 SCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQ--SRCSISKISEHVVLTSVTTV 423
           SCC  G+      +    R+S  S KSL+ Q  +  +ISK+SE VVLTS++T+
Sbjct: 380 SCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTL 432


>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
          Length = 430

 Score =  193 bits (490), Expect = 3e-49
 Identities = 126/355 (35%), Positives = 180/355 (50%), Gaps = 46/355 (12%)

Query: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107
           + I AY  +F++ +VGNTLVC  V +N HM TVTN FI+NL+++D+LV   C+P +L+ +
Sbjct: 45  MFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDN 104

Query: 108 ITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILG 167
           +   W F +A CK+   +Q +SVS +V TL  IA++R+  I HP   K T R+A  +I  
Sbjct: 105 LITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAV 164

Query: 168 IWAVSLAIMVPQAAVM----ECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVT 223
           IWA++L IM P A  +    E    + +  NR+     C E W +    ++Y +  F   
Sbjct: 165 IWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHI 224

Query: 224 YLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAF 283
           YLAPL L+ + Y +I RKL   Q PG                          P P     
Sbjct: 225 YLAPLALIVVMYARIARKLC--QAPG--------------------------PAPGGEE- 255

Query: 284 LAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFS 343
            A+ +  R R +   ML++V L F L +LP+  L +L     +         VYA F F+
Sbjct: 256 AADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYA-FPFA 314

Query: 344 HWLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHK 398
           HWL + NS+ANPIIY + +  FR  F+AAF   L             PR S SHK
Sbjct: 315 HWLAFFNSSANPIIYGYFNENFRRGFQAAFRARL------------CPRPSGSHK 357


>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
          Length = 420

 Score =  187 bits (475), Expect = 2e-47
 Identities = 115/352 (32%), Positives = 175/352 (49%), Gaps = 35/352 (9%)

Query: 27  YEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIV 86
           Y D  + Y+   YL+  Q   + I +Y  +F + ++GNT+VC  V RN HM TVTN FI+
Sbjct: 27  YSDINITYV-NYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFIL 85

Query: 87  NLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWY 146
           NL+++D+LV   C+P +LL +I   W FG+ +CK+   +Q +SV+ +V TL  IA+DR+ 
Sbjct: 86  NLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQ 145

Query: 147 AICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSS-----VLPELANRTRLFSV 201
            + +P   K T + A   I+ IW +++ IM P A ++         V     N+T     
Sbjct: 146 CVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYW 205

Query: 202 CDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRP 261
           C E W +    KIY +  F   YLAPL L+ + Y +I   L+   +P T       W   
Sbjct: 206 CREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVV 265

Query: 262 SDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLK 321
           S                            R ++K  KML++V L+F L +LP+  L +L 
Sbjct: 266 S----------------------------RKKQKIIKMLLIVALLFILSWLPLWTLMMLS 297

Query: 322 RVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
               +         +Y  + F+HWL + NS+ NPIIY F +  FR  F+ AF
Sbjct: 298 DYADLSPNELQIINIY-IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAF 348


>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
          Length = 522

 Score =  187 bits (475), Expect = 2e-47
 Identities = 115/352 (32%), Positives = 175/352 (49%), Gaps = 35/352 (9%)

Query: 27  YEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIV 86
           Y D  + Y+   YL+  Q   + I +Y  +F + ++GNT+VC  V RN HM TVTN FI+
Sbjct: 129 YSDINITYV-NYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFIL 187

Query: 87  NLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWY 146
           NL+++D+LV   C+P +LL +I   W FG+ +CK+   +Q +SV+ +V TL  IA+DR+ 
Sbjct: 188 NLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQ 247

Query: 147 AICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSS-----VLPELANRTRLFSV 201
            + +P   K T + A   I+ IW +++ IM P A ++         V     N+T     
Sbjct: 248 CVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYW 307

Query: 202 CDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRP 261
           C E W +    KIY +  F   YLAPL L+ + Y +I   L+   +P T       W   
Sbjct: 308 CREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVV 367

Query: 262 SDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLK 321
           S                            R ++K  KML++V L+F L +LP+  L +L 
Sbjct: 368 S----------------------------RKKQKIIKMLLIVALLFILSWLPLWTLMMLS 399

Query: 322 RVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
               +         +Y  + F+HWL + NS+ NPIIY F +  FR  F+ AF
Sbjct: 400 DYADLSPNELQIINIY-IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAF 450


>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
          Length = 423

 Score =  187 bits (475), Expect = 2e-47
 Identities = 115/352 (32%), Positives = 175/352 (49%), Gaps = 35/352 (9%)

Query: 27  YEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIV 86
           Y D  + Y+   YL+  Q   + I +Y  +F + ++GNT+VC  V RN HM TVTN FI+
Sbjct: 30  YSDINITYV-NYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFIL 88

Query: 87  NLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWY 146
           NL+++D+LV   C+P +LL +I   W FG+ +CK+   +Q +SV+ +V TL  IA+DR+ 
Sbjct: 89  NLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQ 148

Query: 147 AICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSS-----VLPELANRTRLFSV 201
            + +P   K T + A   I+ IW +++ IM P A ++         V     N+T     
Sbjct: 149 CVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYW 208

Query: 202 CDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRP 261
           C E W +    KIY +  F   YLAPL L+ + Y +I   L+   +P T       W   
Sbjct: 209 CREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVV 268

Query: 262 SDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLK 321
           S                            R ++K  KML++V L+F L +LP+  L +L 
Sbjct: 269 S----------------------------RKKQKIIKMLLIVALLFILSWLPLWTLMMLS 300

Query: 322 RVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
               +         +Y  + F+HWL + NS+ NPIIY F +  FR  F+ AF
Sbjct: 301 DYADLSPNELQIINIY-IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAF 351


>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
          Length = 370

 Score =  159 bits (401), Expect = 6e-39
 Identities = 101/329 (30%), Positives = 166/329 (50%), Gaps = 41/329 (12%)

Query: 44  QYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPAS 103
           Q + +++  Y  V VV LVGN L+ L + R   +  VTN+ I NL+L+DVL+   C+P +
Sbjct: 58  QLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLT 117

Query: 104 LLVDIT-ESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRAR 162
           L        W+FG  LC ++ +LQ V+V V+V TL+ IA+DR+  + HPL  + + R + 
Sbjct: 118 LAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSA 177

Query: 163 GSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERW-ADDLYPKIYHSCFFI 221
            ++L IWA+S  + +P A       + P          +C+E W + +   ++Y     +
Sbjct: 178 YAVLAIWALSAVLALPAAVHTYHVELKPHDVR------LCEEFWGSQERQRQLYAWGLLL 231

Query: 222 VTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRAR 281
           VTYL PL ++ ++Y ++  KL  R +PG  +    +W R                     
Sbjct: 232 VTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDR--------------------- 270

Query: 282 AFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFT 341
                      RR+T  +L+VV++VFA+C+LP+ V N+L+    +   A D  A      
Sbjct: 271 ---------ARRRRTFCLLVVVVVVFAVCWLPLHVFNLLR---DLDPHAIDPYAFGLVQL 318

Query: 342 FSHWLVYANSAANPIIYNFLSGKFREQFK 370
             HWL  +++  NP IY +L   FRE+ +
Sbjct: 319 LCHWLAMSSACYNPFIYAWLHDSFREELR 347


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score =  157 bits (396), Expect = 2e-38
 Identities = 97/339 (28%), Positives = 179/339 (52%), Gaps = 31/339 (9%)

Query: 42  PKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLP 101
           P + +  L+   V +F +AL GN LV   V R+  MRTVTN FI +L+L+D+L+T  C+P
Sbjct: 41  PGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIP 100

Query: 102 ASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFK--STAR 159
            ++L +I+++WL G  +CK++P++Q+ +V   +LT++ IA++R   + HP   K   T R
Sbjct: 101 VTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNR 160

Query: 160 RARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCF 219
           RA   +  +W V++ +  P   V +       L  +  +   C E W   ++ KIY +  
Sbjct: 161 RAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHI--CCLEEWTSPVHQKIYTTFI 218

Query: 220 FIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPR 279
            ++ +L PL +M + Y +I  +LW +             KR  D  G + + + G+    
Sbjct: 219 LVILFLLPLMVMLILYSKIGYELWIK-------------KRVGD--GSVLRTIHGK---- 259

Query: 280 ARAFLAEVKQMRARRKTAKMLMV-VLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYA 338
                 E+ ++  ++K A ++MV V+ +FA+C+ P  V++++   +  F +  D   +  
Sbjct: 260 ------EMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIE-YSNFEKEYDDVTIKM 312

Query: 339 CFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCL 377
            F     + ++NS  NPI+Y F++  F++   +A   C+
Sbjct: 313 IFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCI 351


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score =  156 bits (395), Expect = 3e-38
 Identities = 116/398 (29%), Positives = 196/398 (49%), Gaps = 38/398 (9%)

Query: 46  EW---VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPA 102
           EW   V I  Y  +F+++++GNTLV   + RN  MRTVTN F+++L+++D+++   C+P 
Sbjct: 38  EWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPF 97

Query: 103 SLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFK--STARR 160
           +L+ ++ + ++FG A+CK   Y    SVSV+   L  I+L+R+ AIC PL  +   T   
Sbjct: 98  NLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSH 157

Query: 161 ARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFF 220
           A   I   W +S  IM P       S+++P   N  +  ++C     +D+  + +H+   
Sbjct: 158 ALKVIAATWCLSFTIMTPYPIY---SNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLL 214

Query: 221 IVTYLAPLGLMAMAYFQIFRKLW-------------GRQIPGTTSA---------LVRNW 258
           ++ +L P  +M +AY  I  +L+               + P TTS+          ++  
Sbjct: 215 LILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKT 274

Query: 259 KRPSD-QLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVL 317
           + P   +L  L  G S     R R+  +    + A+++  +ML+V++++F LC++PI   
Sbjct: 275 RPPRKLELRQLSTGSSSRAN-RIRS-NSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSA 332

Query: 318 NVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCL 377
           N  +        +++R       +F   L Y +S  NPIIY F++ +FR  F A F CC 
Sbjct: 333 NAWR---AYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCC- 388

Query: 378 PGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHV 415
           P  GP G+               SL SR S S +S  V
Sbjct: 389 PNPGPPGARGEVGEEEEGGTTGASL-SRFSYSHMSASV 425


>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
          Length = 381

 Score =  156 bits (395), Expect = 3e-38
 Identities = 100/334 (29%), Positives = 167/334 (50%), Gaps = 49/334 (14%)

Query: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107
           VLI AY ++ ++ ++GN+LV   V +   MRTVTN+FI NL++AD+LV  +CLP +L   
Sbjct: 52  VLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYT 111

Query: 108 ITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILG 167
           +   W  G  LC ++PY Q ++V V+ +TL+ IALDR   I + L  K  ++R    I+G
Sbjct: 112 LMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESK-ISKRISFLIIG 170

Query: 168 I-WAVSLAIMVPQAAVMECS--SVLPELANRTRLFSVCDERWADD---LYPKIYHSCFFI 221
           + W +S  +  P A   E S   ++P+          C E+W  +   +Y  +Y     +
Sbjct: 171 LAWGISALLASPLAIFREYSLIEIIPDFE-----IVACTEKWPGEEKSIYGTVYSLSSLL 225

Query: 222 VTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRAR 281
           + Y+ PLG+++ +Y +I+ KL     PG                                
Sbjct: 226 ILYVLPLGIISFSYTRIWSKLKNHVSPGA------------------------------- 254

Query: 282 AFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFT 341
              A     + R+KT KML+ V++VFA+ +LP   L+  +    +  Q  D +     FT
Sbjct: 255 ---ANDHYHQRRQKTTKMLVCVVVVFAVSWLP---LHAFQLAVDIDSQVLDLKEYKLIFT 308

Query: 342 FSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375
             H +   ++ ANP++Y +++  +R+ F +AF C
Sbjct: 309 VFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRC 342


>gi|7669548 tachykinin receptor 3 [Homo sapiens]
          Length = 465

 Score =  150 bits (378), Expect = 3e-36
 Identities = 108/376 (28%), Positives = 178/376 (47%), Gaps = 56/376 (14%)

Query: 4   SATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVG 63
           S++P A +G+P  S  PS    +  ++F++  WR  L      W L  AY  V  VA++G
Sbjct: 52  SSSPSA-LGLPVASPAPSQPWANLTNQFVQPSWRIAL------WSL--AYGVVVAVAVLG 102

Query: 64  NTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIP 123
           N +V   +  +  MRTVTNYF+VNL+ +D  + A     + +  +   W FG   C+   
Sbjct: 103 NLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQN 162

Query: 124 YLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVM 183
           +    +V  ++ +++ IA+DR+ AI  PL  + +A   +  I  IW ++  +  PQ    
Sbjct: 163 FFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYS 222

Query: 184 ECSSVLPELANRTRLFSVCDERWADDLYPK---IYHSCFFIVTYLAPLGLMAMAYFQIFR 240
           + + V+P    RT    +C  +W +   PK    YH    I+ Y  PL +M + Y  +  
Sbjct: 223 K-TKVMP---GRT----LCFVQWPEG--PKQHFTYHIIVIILVYCFPLLIMGITYTIVGI 272

Query: 241 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML 300
            LWG +IPG T                                    +Q++A+RK  KM+
Sbjct: 273 TLWGGEIPGDTCDKYH-------------------------------EQLKAKRKVVKMM 301

Query: 301 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF 360
           ++V++ FA+C+LP  +  +L  ++    +    + VY     S WL  +++  NPIIY  
Sbjct: 302 IIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLA---SFWLAMSSTMYNPIIYCC 358

Query: 361 LSGKFREQFKAAFSCC 376
           L+ +FR  FK AF  C
Sbjct: 359 LNKRFRAGFKRAFRWC 374


>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
          Length = 407

 Score =  149 bits (375), Expect = 6e-36
 Identities = 107/388 (27%), Positives = 176/388 (45%), Gaps = 59/388 (15%)

Query: 44  QYEWVLI---AAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICL 100
           Q  W ++   AAY  + V ++VGN +V   +  +  MRTVTNYF+VNL+ A+  + A   
Sbjct: 27  QPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNT 86

Query: 101 PASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARR 160
             +    +   W +G   CK   +    +V  ++ +++ +A DR+ AI HPL  + +A  
Sbjct: 87  VVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA 146

Query: 161 ARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWAD---DLYPKIYHS 217
            +  I  IW ++L +  PQ      +  +P          VC   W +    +Y K+YH 
Sbjct: 147 TKVVICVIWVLALLLAFPQ-GYYSTTETMPSRV-------VCMIEWPEHPNKIYEKVYHI 198

Query: 218 CFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQ 277
           C  ++ Y  PL ++  AY  +   LW  +IPG +S                         
Sbjct: 199 CVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH--------------------- 237

Query: 278 PRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVY 337
                     +Q+ A+RK  KM++VV+  FA+C+LP  +  +L  +          + VY
Sbjct: 238 ----------EQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVY 287

Query: 338 ACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCC-LPGLGPCGSLKAPSPRSSAS 396
                  WL  +++  NPIIY  L+ +FR  FK AF CC     G    L+  S R    
Sbjct: 288 LAIM---WLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTR---- 340

Query: 397 HKSLSLQSRCSISKISEHVVLTSVTTVL 424
                LQ++ S+ K+S   + T+++TV+
Sbjct: 341 ----YLQTQGSVYKVSR--LETTISTVV 362


>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
          Length = 423

 Score =  147 bits (371), Expect = 2e-35
 Identities = 100/333 (30%), Positives = 167/333 (50%), Gaps = 46/333 (13%)

Query: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107
           +LI AY  + V +L GN LVC  +++N  M + T+ FIVNL++AD+++T +  P +L+  
Sbjct: 73  LLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRF 132

Query: 108 ITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILG 167
           +  +W+FG  +C V  + Q  S+ V+ LTL+ IA+DR   I HPL  + +  +    I  
Sbjct: 133 VNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAV 192

Query: 168 IWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVC--DERWADDLYPKIYHSCFFIVTYL 225
           IW ++    +P A    C  +     +   + S+C  D     DL+ K      FI+ Y+
Sbjct: 193 IWTMATFFSLPHAI---CQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYI 249

Query: 226 APLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLA 285
            PL ++++AY ++ +KLW                   + +GD+              + A
Sbjct: 250 LPLLIISVAYARVAKKLW-----------------LCNMIGDV----------TTEQYFA 282

Query: 286 EVKQMRARRKTAKMLMVVLLVFALCYLPIS--VLNVLKRVFGMFRQASDREAVYACFTFS 343
                R ++KT KMLM+V+++FALC+ P++  VL +  +V           A+Y  F   
Sbjct: 283 ---LRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLSSKVI------RTNNALYFAF--- 330

Query: 344 HWLVYANSAANPIIYNFLSGKFREQFKAAFSCC 376
           HW   +++  NP IY +L+  FR + KA  S C
Sbjct: 331 HWFAMSSTCYNPFIYCWLNENFRIELKALLSMC 363


>gi|157426873 tachykinin receptor 2 [Homo sapiens]
          Length = 398

 Score =  144 bits (363), Expect = 2e-34
 Identities = 97/329 (29%), Positives = 157/329 (47%), Gaps = 46/329 (13%)

Query: 52  AYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITES 111
           AY+A+ +VA+ GN +V   +  +  MRTVTNYFIVNL+LAD+ + A     + +      
Sbjct: 39  AYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNI 98

Query: 112 WLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAV 171
           W FG A C         ++ V++ +++ IA DR+ AI HP   + +A   +  I GIW V
Sbjct: 99  WYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLV 158

Query: 172 SLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPK---IYHSCFFIVTYLAPL 228
           +LA+  PQ      +  + + A +      C   W +D   K   +YH     + Y  PL
Sbjct: 159 ALALASPQC--FYSTVTMDQGATK------CVVAWPEDSGGKTLLLYHLVVIALIYFLPL 210

Query: 229 GLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVK 288
            +M +AY  I   LW R +PG                               +A  A ++
Sbjct: 211 AVMFVAYSVIGLTLWRRAVPG------------------------------HQAHGANLR 240

Query: 289 QMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQ-ASDREAVYACFTFSHWLV 347
            ++A +K  K +++V+L FA+C+LP  +  +L    G F++     + +   +    WL 
Sbjct: 241 HLQAMKKFVKTMVLVVLTFAICWLPYHLYFIL----GSFQEDIYCHKFIQQVYLALFWLA 296

Query: 348 YANSAANPIIYNFLSGKFREQFKAAFSCC 376
            +++  NPIIY  L+ +FR  F+ AF CC
Sbjct: 297 MSSTMYNPIIYCCLNHRFRSGFRLAFRCC 325


>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
          Length = 398

 Score =  144 bits (362), Expect = 2e-34
 Identities = 100/334 (29%), Positives = 153/334 (45%), Gaps = 41/334 (12%)

Query: 47  WVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106
           W++   + A+ ++ LVGN+LV   + R+  MRTVTN++I NL+  DV     C+P + L+
Sbjct: 43  WLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALL 102

Query: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPL--LFKSTARRARGS 164
                W+ G  +CK + Y+Q VSV     TL+ +++DRWY    PL  L + T R A   
Sbjct: 103 YPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAV 162

Query: 165 ILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224
            L IW  S A+  P  A       L  L+   R +  C E +      + +     +  Y
Sbjct: 163 SLSIWVGSAAVSAPVLA-------LHRLSPGPRAY--CSEAFPSRALERAFALYNLLALY 213

Query: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
           L PL      Y  + R L GR                          ++  P P   A  
Sbjct: 214 LLPLLATCACYAAMLRHL-GR--------------------------VAVRPAPADSALQ 246

Query: 285 AEVKQMRA---RRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFT 341
            +V   RA   R K ++++  V+L+FA C+ PI +  VL+ +           A YA  T
Sbjct: 247 GQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKT 306

Query: 342 FSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375
           ++H + Y+NSA NP++Y FL   FR+ F+    C
Sbjct: 307 WAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score =  144 bits (362), Expect = 2e-34
 Identities = 108/399 (27%), Positives = 188/399 (47%), Gaps = 46/399 (11%)

Query: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107
           + I  Y  +F++++ GN L+ + +  +  +RTVTN F+++L+++D+L+   C+P +LL +
Sbjct: 56  IRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPN 115

Query: 108 ITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFK--STARRARGSI 165
           +  +++FG  +CK + YL  VSVSV+ L+L  IAL+R+ AIC PL  +   T   A   I
Sbjct: 116 LMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVI 175

Query: 166 LGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYL 225
           +  W +S  +MVP         V P +         C  RW      + +     ++ + 
Sbjct: 176 VATWLLSGLLMVPYPVYTVVQPVGPRVLQ-------CVHRWPSARVRQTWSVLLLLLLFF 228

Query: 226 APLGLMAMAYFQIFRKLW-GRQIPGTTSALVRNWKRPSDQLGDL---------EQGLSGE 275
            P  +MA+AY  I R+L+ G +  G + +  ++  R    L            E G  GE
Sbjct: 229 IPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGE 288

Query: 276 PQ-------PRARAFL---------------AEVKQMRARRKTAKMLMVVLLVFALCYLP 313
                    PR+R  L                   ++ A+++  +ML+V++++F LC+LP
Sbjct: 289 DSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLP 348

Query: 314 ISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
           +   N  +   G     + R    A  +F H L YA++  NP++Y F+  +FR+      
Sbjct: 349 VYSANTWRAFDG---PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETC 405

Query: 374 SCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKIS 412
           + C P   P  +     P       S++  SR S + IS
Sbjct: 406 ARCCP--RPPRARPRALPDEDPPTPSIASLSRLSYTTIS 442


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score =  142 bits (359), Expect = 4e-34
 Identities = 102/337 (30%), Positives = 167/337 (49%), Gaps = 58/337 (17%)

Query: 47  WVLIAAYVAVFVVALVGNTLVCLAVWRNH--HMRTVTNYFIVNLSLADVLVTAICLPASL 104
           +V +  +  +F + ++GN+LV   + R+     R+ TN FI+NLS+AD+     C+P   
Sbjct: 34  FVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQA 93

Query: 105 LVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGS 164
            V    +W+ G  +CK I Y   VS+ V++ TL+ +++DR+ AI H     S+ R +R +
Sbjct: 94  TVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRR-SSSLRVSRNA 152

Query: 165 ILG---IWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFI 221
           +LG   IWA+S+A+  P A         P  +N+T     C E+W D  + K Y  C F+
Sbjct: 153 LLGVGCIWALSIAMASPVA--YHQGLFHPRASNQT----FCWEQWPDPRHKKAYVVCTFV 206

Query: 222 VTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRAR 281
             YL PL L+   Y ++   L  +         ++N  + S+                  
Sbjct: 207 FGYLLPLLLICFCYAKVLNHLHKK---------LKNMSKKSE------------------ 239

Query: 282 AFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFT 341
                     +++KTA+ ++VV++VF + +LP  +++ L   FG+F          A F 
Sbjct: 240 ---------ASKKKTAQTVLVVVVVFGISWLPHHIIH-LWAEFGVF------PLTPASFL 283

Query: 342 F---SHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375
           F   +H L Y+NS+ NPIIY FLS  FR+ +K  F C
Sbjct: 284 FRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKC 320


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score =  135 bits (341), Expect = 5e-32
 Identities = 89/336 (26%), Positives = 159/336 (47%), Gaps = 34/336 (10%)

Query: 47  WVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106
           +V+ A Y  + ++ L+GN  +         MR V N FI +L+L D+L+   C P     
Sbjct: 41  YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 100

Query: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSIL 166
            + + WLFG   CK+IP++Q  SV V+V TL+ ++ DR+ AI  P+  +++    +  + 
Sbjct: 101 YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLK 160

Query: 167 G--IWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224
              IW +S+ + +P+A   +      E  N+T   S      +++L+PKI+    F+V Y
Sbjct: 161 AAFIWIISMLLAIPEAVFSDLHPFHEESTNQT-FISCAPYPHSNELHPKIHSMASFLVFY 219

Query: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
           + PL ++++ Y+ I + L           +   +  P +  G++                
Sbjct: 220 VIPLSIISVYYYFIAKNL-----------IQSAYNLPVE--GNIH--------------- 251

Query: 285 AEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSH 344
              KQ+ +R++ AK ++V + +FA C+LP  V+ + +     + +       +     + 
Sbjct: 252 -VKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYH--YSEVDTSMLHFVTSICAR 308

Query: 345 WLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGL 380
            L + NS  NP     LS  FR+QF     CC PGL
Sbjct: 309 LLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGL 344


>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
           receptor [Homo sapiens]
          Length = 368

 Score =  135 bits (341), Expect = 5e-32
 Identities = 89/336 (26%), Positives = 159/336 (47%), Gaps = 34/336 (10%)

Query: 47  WVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106
           +V+ A Y  + ++ L+GN  +         MR V N FI +L+L D+L+   C P     
Sbjct: 25  YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 84

Query: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSIL 166
            + + WLFG   CK+IP++Q  SV V+V TL+ ++ DR+ AI  P+  +++    +  + 
Sbjct: 85  YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLK 144

Query: 167 G--IWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224
              IW +S+ + +P+A   +      E  N+T   S      +++L+PKI+    F+V Y
Sbjct: 145 AAFIWIISMLLAIPEAVFSDLHPFHEESTNQT-FISCAPYPHSNELHPKIHSMASFLVFY 203

Query: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
           + PL ++++ Y+ I + L           +   +  P +  G++                
Sbjct: 204 VIPLSIISVYYYFIAKNL-----------IQSAYNLPVE--GNIH--------------- 235

Query: 285 AEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSH 344
              KQ+ +R++ AK ++V + +FA C+LP  V+ + +     + +       +     + 
Sbjct: 236 -VKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYH--YSEVDTSMLHFVTSICAR 292

Query: 345 WLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGL 380
            L + NS  NP     LS  FR+QF     CC PGL
Sbjct: 293 LLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGL 328


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score =  134 bits (337), Expect = 2e-31
 Identities = 95/320 (29%), Positives = 147/320 (45%), Gaps = 49/320 (15%)

Query: 53  YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW 112
           +  +F+V  VGNTLV   + R     + TN FI+NL +AD+     C+P    +   + W
Sbjct: 32  FALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGW 91

Query: 113 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKS--TARRARGSILGIWA 170
           +FG  LCK + +L  +++  +  TL+ ++LDR+ AI +PL  +   T R A  +I  IW 
Sbjct: 92  VFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWG 151

Query: 171 VSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGL 230
           +SL    P  +    S    +LAN T    VC   W+     +    C F+ +YL P+ +
Sbjct: 152 LSLLFSGPYLSYYRQS----QLANLT----VCHPAWSAP-RRRAMDICTFVFSYLLPVLV 202

Query: 231 MAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQM 290
           + + Y +  R LW    P    +  R                                  
Sbjct: 203 LGLTYARTLRYLWRAVDPVAAGSGAR---------------------------------- 228

Query: 291 RARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYAN 350
           RA+RK  +M+++V  +F LC++P   L +L   FG F       A YA    SH + YAN
Sbjct: 229 RAKRKVTRMILIVAALFCLCWMPHHAL-ILCVWFGQFPLT---RATYALRILSHLVSYAN 284

Query: 351 SAANPIIYNFLSGKFREQFK 370
           S  NPI+Y  +S  FR+ F+
Sbjct: 285 SCVNPIVYALVSKHFRKGFR 304


>gi|161484640 neuromedin B receptor [Homo sapiens]
          Length = 390

 Score =  133 bits (335), Expect = 3e-31
 Identities = 100/370 (27%), Positives = 168/370 (45%), Gaps = 38/370 (10%)

Query: 9   AQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVC 68
           + + V  G+ E   VP  +E +FL               V+ + Y+ +  V L+GN ++ 
Sbjct: 7   SNLSVTTGANESGSVPEGWERDFLPAS-DGTTTELVIRCVIPSLYLLIITVGLLGNIMLV 65

Query: 69  LAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAV 128
                N  MR+V N FI NL+  D+L+   C+P        + W+FG   CK+IP +Q  
Sbjct: 66  KIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLT 125

Query: 129 SVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSI--LGIWAVSLAIMVPQAAVMECS 186
           SV V+V TL+ ++ DR+ AI +P+  +++    R  +  +GIW VS+ + VP+A   E +
Sbjct: 126 SVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVA 185

Query: 187 SVLPELANRTRLFSVC-DERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGR 245
            +   L N +  F+ C      D+L+PKI+    F+V +L PL ++++ Y+ I       
Sbjct: 186 RI-SSLDNSS--FTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHI------- 235

Query: 246 QIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLL 305
                   L+++              L GE     +      KQM  R++ AK+++V + 
Sbjct: 236 -----AKTLIKS-----------AHNLPGEYNEHTK------KQMETRKRLAKIVLVFVG 273

Query: 306 VFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKF 365
            F  C+ P  +L  + R F  + +             +  L + NS  NP     LS  F
Sbjct: 274 CFIFCWFPNHIL-YMYRSFN-YNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESF 331

Query: 366 REQFKAAFSC 375
           R  F +   C
Sbjct: 332 RRHFNSQLCC 341


>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
          Length = 398

 Score =  132 bits (332), Expect = 6e-31
 Identities = 101/355 (28%), Positives = 172/355 (48%), Gaps = 26/355 (7%)

Query: 28  EDEFLRYLWRDYLYPK-----QYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTN 82
           E+E +  L +  L P+     +Y+ V I   + +  + +VGN +V L V R  HMRT TN
Sbjct: 2   ENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTN 61

Query: 83  YFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIAL 142
            ++V+L++AD++V       ++   I  SW++G+  C  I YLQ + ++ +  +++   +
Sbjct: 62  CYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTI 121

Query: 143 DRWYAICHPL--LFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFS 200
           +R+ AICHP+   F  T  RA+  I+ +WA +    +    +++    L     +  +  
Sbjct: 122 ERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLD----LNISTYKDAIVI 177

Query: 201 VCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKR 260
            C  + + + Y  IY    F V Y+ P+ L  + Y  I R L+   IP       + WK 
Sbjct: 178 SCGYKISRNYYSPIY-LMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKN 236

Query: 261 PSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVL 320
            S       Q  +       R F + V    +R++  KML VV+++FAL ++P   L V+
Sbjct: 237 DS-----THQNTNLNVNTSNRCFNSTVS---SRKQVTKMLAVVVILFALLWMPYRTLVVV 288

Query: 321 KRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375
                 F  +  +E  +    F    +Y NSA NP+IYN +S KFR  F+   +C
Sbjct: 289 ----NSFLSSPFQENWF--LLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNC 337


>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
          Length = 311

 Score =  130 bits (328), Expect = 2e-30
 Identities = 87/327 (26%), Positives = 146/327 (44%), Gaps = 48/327 (14%)

Query: 44  QYEWVLI---AAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICL 100
           Q  W ++   AAY  + V ++VGN +V   +  +  MRTVTNYF+VNL+ A+  + A   
Sbjct: 27  QPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNT 86

Query: 101 PASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARR 160
             +    +   W +G   CK   +    +V  ++ +++ +A DR+ AI HPL  + +A  
Sbjct: 87  VVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA 146

Query: 161 ARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWAD---DLYPKIYHS 217
            +  I  IW ++L +  PQ      +  +P          VC   W +    +Y K+YH 
Sbjct: 147 TKVVICVIWVLALLLAFPQ-GYYSTTETMPSRV-------VCMIEWPEHPNKIYEKVYHI 198

Query: 218 CFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQ 277
           C  ++ Y  PL ++  AY  +   LW  +IPG +S                         
Sbjct: 199 CVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH--------------------- 237

Query: 278 PRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVY 337
                     +Q+ A+RK  KM++VV+  FA+C+LP  +  +L  +          + VY
Sbjct: 238 ----------EQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVY 287

Query: 338 ACFTFSHWLVYANSAANPIIYNFLSGK 364
                  WL  +++  NPIIY  L+ +
Sbjct: 288 LAIM---WLAMSSTMYNPIIYCCLNDR 311


>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
          Length = 399

 Score =  130 bits (327), Expect = 2e-30
 Identities = 93/335 (27%), Positives = 158/335 (47%), Gaps = 51/335 (15%)

Query: 53  YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW 112
           Y  +  V ++GN ++    ++   M+TV N FI +L+  D+L+   C+P      + E W
Sbjct: 54  YAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGW 113

Query: 113 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILG----- 167
           LFG   CKV+ +++  SV V+V TL+ ++ DR+ A+  PL      R+   +IL      
Sbjct: 114 LFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPL-----ERQPSNAILKTCVKA 168

Query: 168 --IWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDE-RWADDLYPKIYHSCFFIVTY 224
             +W VS+   +P+A      +      N+   F  C     +  L  +I+    F+V Y
Sbjct: 169 GCVWIVSMIFALPEAIFSNVYTFRD--PNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFY 226

Query: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
           + PL ++++ Y  I R L+   +                        +  E Q  AR   
Sbjct: 227 IIPLSIISVYYSLIARTLYKSTL-----------------------NIPTEEQSHAR--- 260

Query: 285 AEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQAS--DREAVYACFT- 341
              KQ+ +R++ A+ ++V++ +FALC+LP    N L  ++  F   +  D  A++  FT 
Sbjct: 261 ---KQIESRKRIARTVLVLVALFALCWLP----NHLLYLYHSFTSQTYVDPSAMHFIFTI 313

Query: 342 FSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCC 376
           FS  L ++NS  NP    +LS  F++ FKA   CC
Sbjct: 314 FSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCC 348


>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
          Length = 384

 Score =  129 bits (325), Expect = 4e-30
 Identities = 86/332 (25%), Positives = 157/332 (47%), Gaps = 36/332 (10%)

Query: 47  WVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106
           + L  AY AV ++ + GN  + + + +   MR VTN  IVNLS +D+LV  +CLP + + 
Sbjct: 41  FTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVY 100

Query: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSIL 166
            + + W+FG A+CK+ P++Q VS++V++ +L  IA++R   I +P  ++   R A   I 
Sbjct: 101 TLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIA 160

Query: 167 GIWAVSLAIMVPQA--AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224
            IW +++A  +P     VM          +  +   VC +++  D +   Y +   ++ Y
Sbjct: 161 VIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQY 220

Query: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
             PL  + + YF+I+ +L                KR ++ +  +            +   
Sbjct: 221 FGPLCFIFICYFKIYIRL----------------KRRNNMMDKMRDN---------KYRS 255

Query: 285 AEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSH 344
           +E K++        ML+ +++ FA+C+LP+++ N    VF    Q          F   H
Sbjct: 256 SETKRINI------MLLSIVVAFAVCWLPLTIFNT---VFDWNHQIIATCNHNLLFLLCH 306

Query: 345 WLVYANSAANPIIYNFLSGKFREQFKAAFSCC 376
                ++  NPI Y FL+  F+   +  F+ C
Sbjct: 307 LTAMISTCVNPIFYGFLNKNFQRDLQFFFNFC 338


>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
          Length = 393

 Score =  129 bits (325), Expect = 4e-30
 Identities = 83/281 (29%), Positives = 136/281 (48%), Gaps = 38/281 (13%)

Query: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107
           V+  A V + +V  +GN +   A+ R   +R +TN  I NL+++D LV  +C P  +   
Sbjct: 64  VIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYY 123

Query: 108 ITE--SWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSI 165
           +    SW  GH LC  + YL+ VS+ V+   L  IA+DR+ AI HPL  +   + A G I
Sbjct: 124 VVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLI 183

Query: 166 LGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADD--LYPKIYHSCFFIVT 223
             +W VS+ I +P +A     +VL  + ++ ++F  C + W  D  LY K Y    F + 
Sbjct: 184 ALVWTVSILIAIP-SAYFTTETVLVIVKSQEKIF--CGQIWPVDQQLYYKSYFLFIFGIE 240

Query: 224 YLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAF 283
           ++ P+  M + Y +I R+LW + +PG  +  +R                           
Sbjct: 241 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIR--------------------------- 273

Query: 284 LAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVF 324
               K++R RRKT  +LM +L  + LC+ P     +++  F
Sbjct: 274 ----KRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFF 310


>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
          Length = 477

 Score =  129 bits (323), Expect = 7e-30
 Identities = 115/402 (28%), Positives = 180/402 (44%), Gaps = 75/402 (18%)

Query: 5   ATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWV----LIAAYVAVFVVA 60
           A+P A + +PP S  P P+                      +W     L+ A + + +VA
Sbjct: 36  ASPPASL-LPPASESPEPL--------------------SQQWTAGMGLLMALIVLLIVA 74

Query: 61  LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK 120
             GN LV +A+ +   ++T+TN FI++L+ AD+++  + +P    + +   W +G   C+
Sbjct: 75  --GNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCE 132

Query: 121 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKS--TARRARGSILGIWAVSLAIMVP 178
           +   +  + V+ ++ TL  IALDR+ AI  P  ++S  T  RARG +  +WA+S  +   
Sbjct: 133 LWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALV--- 189

Query: 179 QAAVMECSSVLPELANRTRLFS------VCDERWADDLYPKIYHSCFFIVTYLAPLGLMA 232
                   S LP L +  R  S        D +  D +  + Y     +V++  PL +MA
Sbjct: 190 --------SFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMA 241

Query: 233 MAYFQIFRKLWGRQIPGTTSALVR------NWKRPSDQLGDLEQGLSGEPQPRARAFLAE 286
             Y ++FR+   +Q+    S   R          PS           G P+P A A  A 
Sbjct: 242 FVYLRVFREA-QKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP 300

Query: 287 VKQMRA------------RRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDRE 334
           +   RA             +K  K L +++ VF LC+LP  + NV+K        A  RE
Sbjct: 301 LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVK--------AFHRE 352

Query: 335 AV-YACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375
            V    F F +WL YANSA NPIIY   S  FR+ F+    C
Sbjct: 353 LVPDRLFVFFNWLGYANSAFNPIIY-CRSPDFRKAFQGLLCC 393


>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
          Length = 375

 Score =  125 bits (315), Expect = 6e-29
 Identities = 88/339 (25%), Positives = 153/339 (45%), Gaps = 53/339 (15%)

Query: 49  LIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDI 108
           ++ +Y    VV ++GN  +     R      VTN  I NL+ +D L+  +C P + +  I
Sbjct: 44  IVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTI 103

Query: 109 TESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGI 168
            + W+FG  LCK+  ++Q +SV+V++L+L  +AL+R   I +P  +K +  +A   I+ I
Sbjct: 104 MDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLI 163

Query: 169 WAVSLAIMVPQAAVMECSSVLPELANRTRLF----SVCDERWADDLYPKIYHSCFFIVTY 224
           W ++  + +P  A     +V  +  ++   F     VC E W    +  IY +   +  Y
Sbjct: 164 WVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQY 223

Query: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
             PLG + + Y +I+R+L                                  Q + R F 
Sbjct: 224 CLPLGFILVCYARIYRRL----------------------------------QRQGRVFH 249

Query: 285 AEVKQMRA--RRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAC--- 339
                +RA   ++   +L+V+++ FA+ +LP+ V N L        +    EA+  C   
Sbjct: 250 KGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSL--------EDWHHEAIPICHGN 301

Query: 340 --FTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCC 376
             F   H L  A++  NP IY FL+  F+++ KA    C
Sbjct: 302 LIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTC 340


>gi|21426829 prokineticin receptor 2 [Homo sapiens]
          Length = 384

 Score =  124 bits (311), Expect = 2e-28
 Identities = 91/328 (27%), Positives = 149/328 (45%), Gaps = 42/328 (12%)

Query: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107
           V+  A   + +V  +GN +   A+ R   +R +TN  I NL+++D LV  IC P  +   
Sbjct: 55  VIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYY 114

Query: 108 ITE--SWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSI 165
           +    SW  GH LC  + YL+ VS+ V+   L  IA+DR+ AI HPL  +   + A   I
Sbjct: 115 VVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLI 174

Query: 166 LGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADD--LYPKIYHSCFFIVT 223
             +W VS+ I +P +A     +VL  + ++ ++F  C + W  D  LY K Y    F V 
Sbjct: 175 ALVWMVSILIAIP-SAYFATETVLFIVKSQEKIF--CGQIWPVDQQLYYKSYFLFIFGVE 231

Query: 224 YLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAF 283
           ++ P+  M + Y +I R+LW + +PG  +  +R                           
Sbjct: 232 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIR--------------------------- 264

Query: 284 LAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVY-ACFTF 342
               K++R RRKT  +LM +L  + LC+ P     +++     F     +E  Y   F  
Sbjct: 265 ----KRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVR---DFFPTVFVKEKHYLTAFYV 317

Query: 343 SHWLVYANSAANPIIYNFLSGKFREQFK 370
              +  +NS  N + +  +     + FK
Sbjct: 318 VECIAMSNSMINTVCFVTVKNNTMKYFK 345


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  124 bits (310), Expect = 2e-28
 Identities = 99/336 (29%), Positives = 163/336 (48%), Gaps = 54/336 (16%)

Query: 49  LIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDI 108
           ++  Y+AV V  L+GN LV   + R+  M+T TN +I NL+LAD LV  + LP      +
Sbjct: 54  IVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLV-LLTLPFQGTDIL 112

Query: 109 TESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPL--LFKSTARRARGSIL 166
              W FG+ALCK +  +   ++  +  TL+ +++DR+ AICHP+  L   T+ +A+   +
Sbjct: 113 LGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNV 172

Query: 167 GIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLA 226
            IWA++  + VP  A+M  + V  E      +  + +     D +  ++  C F+ +++ 
Sbjct: 173 AIWALASVVGVP-VAIMGSAQVEDE-----EIECLVEIPTPQDYWGPVFAICIFLFSFIV 226

Query: 227 PLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAE 286
           P+ ++++ Y  + R+L G ++                        LSG  +         
Sbjct: 227 PVLVISVCYSLMIRRLRGVRL------------------------LSGSRE--------- 253

Query: 287 VKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWL 346
             + R  R+  ++++VV+ VF  C+ P+ V  VL +  G+  Q S   AV A   F   L
Sbjct: 254 --KDRNLRRITRLVLVVVAVFVGCWTPVQVF-VLAQGLGV--QPSSETAV-AILRFCTAL 307

Query: 347 VYANSAANPIIYNFLSGKFREQFKAAFS--CCLPGL 380
            Y NS  NPI+Y FL     E FKA F   CC   L
Sbjct: 308 GYVNSCLNPILYAFLD----ENFKACFRKFCCASAL 339


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.137    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,305,172
Number of Sequences: 37866
Number of extensions: 705763
Number of successful extensions: 5137
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 594
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 3537
Number of HSP's gapped (non-prelim): 1092
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.