BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens] (609 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens] 1209 0.0 gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens] 1141 0.0 gi|22202631 programmed cell death 8 isoform 3 [Homo sapiens] 584 e-167 gi|195927006 programmed cell death 8 isoform 5 [Homo sapiens] 561 e-160 gi|195927004 programmed cell death 8 isoform 4 [Homo sapiens] 523 e-148 gi|226437568 apoptosis-inducing factor, mitochondrion-associated... 113 6e-25 gi|65787454 apoptosis-inducing factor, mitochondrion-associated,... 113 6e-25 gi|21389617 apoptosis-inducing factor, mitochondrion-associated,... 113 6e-25 gi|117168279 ovary-specific acidic protein [Homo sapiens] 57 4e-08 gi|14318424 apoptosis-inducing factor (AIF)-like mitchondrion-as... 51 4e-06 gi|50301238 glutathione reductase [Homo sapiens] 40 0.008 gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain... 38 0.031 gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 36 0.090 gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 36 0.12 gi|65301141 PH domain and leucine rich repeat protein phosphatas... 33 0.58 gi|145199237 transcription elongation factor B polypeptide 3 bin... 33 0.76 gi|239747100 PREDICTED: hypothetical protein XP_002344493 [Homo ... 33 1.00 gi|221139926 NHS-like 1 [Homo sapiens] 32 2.2 gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Hom... 31 3.8 gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Hom... 31 3.8 gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8... 30 4.9 gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 30 6.5 gi|4503571 enolase 1 [Homo sapiens] 30 8.4 gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 30 8.4 >gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens] Length = 609 Score = 1209 bits (3129), Expect = 0.0 Identities = 609/609 (100%), Positives = 609/609 (100%) Query: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPVVQSHHLGSPSRSLASTGASGKDGS 60 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPVVQSHHLGSPSRSLASTGASGKDGS Sbjct: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPVVQSHHLGSPSRSLASTGASGKDGS 60 Query: 61 NLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVP 120 NLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVP Sbjct: 61 NLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVP 120 Query: 121 QDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDD 180 QDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDD Sbjct: 121 QDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDD 180 Query: 181 PNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVK 240 PNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVK Sbjct: 181 PNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVK 240 Query: 241 LNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSIT 300 LNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSIT Sbjct: 241 LNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSIT 300 Query: 301 IIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVM 360 IIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVM Sbjct: 301 IIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVM 360 Query: 361 PNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVN 420 PNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVN Sbjct: 361 PNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVN 420 Query: 421 AELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWS 480 AELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWS Sbjct: 421 AELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWS 480 Query: 481 DLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIP 540 DLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIP Sbjct: 481 DLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIP 540 Query: 541 PSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEV 600 PSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEV Sbjct: 541 PSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEV 600 Query: 601 AKLFNIHED 609 AKLFNIHED Sbjct: 601 AKLFNIHED 609 >gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens] Length = 613 Score = 1141 bits (2952), Expect = 0.0 Identities = 584/614 (95%), Positives = 590/614 (96%), Gaps = 6/614 (0%) Query: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP--VVQSHHLG---SPSRSLASTGAS 55 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP + Q H+ +R +AS+GAS Sbjct: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS 60 Query: 56 GKDGSNLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE 115 G N V LIVG + GAG Y AYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE Sbjct: 61 GGKIDNSVLVLIVGLSTVGAGAY-AYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE 119 Query: 116 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL 175 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL Sbjct: 120 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL 179 Query: 176 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR 235 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR Sbjct: 180 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR 239 Query: 236 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE 295 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE Sbjct: 240 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE 299 Query: 296 VKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRRE 355 VKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRRE Sbjct: 300 VKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRRE 359 Query: 356 GVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFG 415 GVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFG Sbjct: 360 GVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFG 419 Query: 416 GFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ 475 GFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ Sbjct: 420 GFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ 479 Query: 476 SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAS 535 SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAS Sbjct: 480 SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAS 539 Query: 536 EITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHE 595 EITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHE Sbjct: 540 EITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHE 599 Query: 596 DLNEVAKLFNIHED 609 DLNEVAKLFNIHED Sbjct: 600 DLNEVAKLFNIHED 613 >gi|22202631 programmed cell death 8 isoform 3 [Homo sapiens] Length = 326 Score = 584 bits (1505), Expect = e-167 Identities = 291/291 (100%), Positives = 291/291 (100%) Query: 319 ARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIK 378 ARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIK Sbjct: 36 ARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIK 95 Query: 379 LKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACF 438 LKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACF Sbjct: 96 LKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACF 155 Query: 439 YDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSL 498 YDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSL Sbjct: 156 YDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSL 215 Query: 499 PTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGK 558 PTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGK Sbjct: 216 PTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGK 275 Query: 559 GVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED 609 GVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED Sbjct: 276 GVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED 326 Score = 74.3 bits (181), Expect = 3e-13 Identities = 35/35 (100%), Positives = 35/35 (100%) Query: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP 35 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP Sbjct: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP 35 >gi|195927006 programmed cell death 8 isoform 5 [Homo sapiens] Length = 324 Score = 561 bits (1447), Expect = e-160 Identities = 293/323 (90%), Positives = 299/323 (92%), Gaps = 6/323 (1%) Query: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP--VVQSHHLG---SPSRSLASTGAS 55 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP + Q H+ +R +AS+GAS Sbjct: 1 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS 60 Query: 56 GKDGSNLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE 115 G N V LIVG + GAG Y AYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE Sbjct: 61 GGKIDNSVLVLIVGLSTVGAGAY-AYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE 119 Query: 116 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL 175 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL Sbjct: 120 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL 179 Query: 176 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR 235 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR Sbjct: 180 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR 239 Query: 236 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE 295 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE Sbjct: 240 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE 299 Query: 296 VKSITIIGGGFLGSELACALGRK 318 VKSITIIGGGFLGSELACALGRK Sbjct: 300 VKSITIIGGGFLGSELACALGRK 322 >gi|195927004 programmed cell death 8 isoform 4 [Homo sapiens] Length = 261 Score = 523 bits (1347), Expect = e-148 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 349 MEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGL 408 MEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGL Sbjct: 1 MEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGL 60 Query: 409 EIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGA 468 EIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGA Sbjct: 61 EIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGA 120 Query: 469 AKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSES 528 AKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSES Sbjct: 121 AKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSES 180 Query: 529 ETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKII 588 ETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKII Sbjct: 181 ETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKII 240 Query: 589 KDGEQHEDLNEVAKLFNIHED 609 KDGEQHEDLNEVAKLFNIHED Sbjct: 241 KDGEQHEDLNEVAKLFNIHED 261 >gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3 isoform 3 [Homo sapiens] Length = 604 Score = 113 bits (282), Expect = 6e-25 Identities = 114/418 (27%), Positives = 179/418 (42%), Gaps = 51/418 (12%) Query: 74 GAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLI 133 G + ++ E EK Y R S L +++ K A S P S L++ Sbjct: 153 GLDSLHKFQVKIEKEKVY-VRASKQALQLQRRTKVMAKCIS-----PSAGYSSSTNVLIV 206 Query: 134 GGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWN 193 G G A A ++R R+++ + D LPY RP LSK L + Sbjct: 207 GAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSL-----------------D 249 Query: 194 GKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCL 253 + + +P F+ + G+ VLT +VV +DVR V DG ++ Y K L Sbjct: 250 TQPEQLALRPKEFFRAY---------GIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL 300 Query: 254 IATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELAC 313 +A G +P++LS G EV++ T+ R D + +++R +++ ++G GFLG E+A Sbjct: 301 LAPGSSPKTLSC---KGKEVENVFTI-RTPEDANRVVRLARG-RNVVVVGAGFLGMEVAA 355 Query: 314 ALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSG 373 L KA ++ V++L E+ + L E + M+ VK V + G Sbjct: 356 YLTEKAHSV--SVVEL--EETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEG 411 Query: 374 KLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQAR-SNIWV 431 KL + LK + V D V +G P + G+ +DS G VN +Q ++ Sbjct: 412 KLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSR-GFIPVNKMMQTNVPGVFA 470 Query: 432 AGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGENMTG-----AAKPYWHQSMFWSDL 482 AGDA F R+V H A GR+A +NM + PY +MF L Sbjct: 471 AGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSL 528 >gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3 isoform 2 [Homo sapiens] Length = 598 Score = 113 bits (282), Expect = 6e-25 Identities = 114/418 (27%), Positives = 179/418 (42%), Gaps = 51/418 (12%) Query: 74 GAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLI 133 G + ++ E EK Y R S L +++ K A S P S L++ Sbjct: 147 GLDSLHKFQVKIEKEKVY-VRASKQALQLQRRTKVMAKCIS-----PSAGYSSSTNVLIV 200 Query: 134 GGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWN 193 G G A A ++R R+++ + D LPY RP LSK L + Sbjct: 201 GAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSL-----------------D 243 Query: 194 GKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCL 253 + + +P F+ + G+ VLT +VV +DVR V DG ++ Y K L Sbjct: 244 TQPEQLALRPKEFFRAY---------GIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL 294 Query: 254 IATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELAC 313 +A G +P++LS G EV++ T+ R D + +++R +++ ++G GFLG E+A Sbjct: 295 LAPGSSPKTLSC---KGKEVENVFTI-RTPEDANRVVRLARG-RNVVVVGAGFLGMEVAA 349 Query: 314 ALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSG 373 L KA ++ V++L E+ + L E + M+ VK V + G Sbjct: 350 YLTEKAHSV--SVVEL--EETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEG 405 Query: 374 KLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQAR-SNIWV 431 KL + LK + V D V +G P + G+ +DS G VN +Q ++ Sbjct: 406 KLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSR-GFIPVNKMMQTNVPGVFA 464 Query: 432 AGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGENMTG-----AAKPYWHQSMFWSDL 482 AGDA F R+V H A GR+A +NM + PY +MF L Sbjct: 465 AGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSL 522 >gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3 isoform 1 [Homo sapiens] Length = 605 Score = 113 bits (282), Expect = 6e-25 Identities = 114/418 (27%), Positives = 179/418 (42%), Gaps = 51/418 (12%) Query: 74 GAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLI 133 G + ++ E EK Y R S L +++ K A S P S L++ Sbjct: 147 GLDSLHKFQVKIEKEKVY-VRASKQALQLQRRTKVMAKCIS-----PSAGYSSSTNVLIV 200 Query: 134 GGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWN 193 G G A A ++R R+++ + D LPY RP LSK L + Sbjct: 201 GAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSL-----------------D 243 Query: 194 GKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCL 253 + + +P F+ + G+ VLT +VV +DVR V DG ++ Y K L Sbjct: 244 TQPEQLALRPKEFFRAY---------GIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL 294 Query: 254 IATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELAC 313 +A G +P++LS G EV++ T+ R D + +++R +++ ++G GFLG E+A Sbjct: 295 LAPGSSPKTLSC---KGKEVENVFTI-RTPEDANRVVRLARG-RNVVVVGAGFLGMEVAA 349 Query: 314 ALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSG 373 L KA ++ V++L E+ + L E + M+ VK V + G Sbjct: 350 YLTEKAHSV--SVVEL--EETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEG 405 Query: 374 KLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQAR-SNIWV 431 KL + LK + V D V +G P + G+ +DS G VN +Q ++ Sbjct: 406 KLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSR-GFIPVNKMMQTNVPGVFA 464 Query: 432 AGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGENMTG-----AAKPYWHQSMFWSDL 482 AGDA F R+V H A GR+A +NM + PY +MF L Sbjct: 465 AGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSL 522 >gi|117168279 ovary-specific acidic protein [Homo sapiens] Length = 240 Score = 57.4 bits (137), Expect = 4e-08 Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 17/123 (13%) Query: 47 RSLASTGASGKDGSNLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQ 106 R ++S G GSN++Y+L+VG TV+ AG YYAYKT+ D+ ++ E + L +++ Sbjct: 31 RRMSSNRFPGSSGSNMIYYLVVGVTVS-AGGYYAYKTVTSDQAKHTEHKTNL-----KEK 84 Query: 107 KKAALSASEGEE---VPQDKAPSHVPFLLIGGGTAAFAAARSIRARD-PGARVLIVSEDP 162 KA + +GE+ +KA S P LI A + A + P A V+++ E Sbjct: 85 TKAEIHPFQGEKENVAETEKASSEAPEELI-------VEAEVVDAEESPSATVVVIKEAS 137 Query: 163 ELP 165 P Sbjct: 138 ACP 140 >gi|14318424 apoptosis-inducing factor (AIF)-like mitchondrion-associated inducer of death [Homo sapiens] Length = 373 Score = 50.8 bits (120), Expect = 4e-06 Identities = 49/218 (22%), Positives = 97/218 (44%), Gaps = 22/218 (10%) Query: 229 VVQLDVRDNMVKLNDGSQITYEKCLIATGGT---PRSLSAIDRAGAEVKSRTTLFRKIGD 285 VV +D+++ MV L G + + ++ATG T P + + A +++ + R++ Sbjct: 82 VVGIDLKNQMVLLQGGEALPFSHLILATGSTGPFPGKFNEVSSQQAAIQAYEDMVRQV-- 139 Query: 286 FRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLS 345 + + I ++GGG G E+A + K EV + + K L + Sbjct: 140 --------QRSRFIVVVGGGSAGVEMAAEI--KTEYPEKEVTLIHSQVALADKELLPSVR 189 Query: 346 NWTMEKVRREGVKVMPNAIV---QSVGVSSGKLLIKLK--DGRKVETDHIVAAVGLEPNV 400 E + R+GV+++ + V + + ++ + IK++ G +V T+ ++ G++ N Sbjct: 190 QEVKEILLRKGVQLLLSERVSNLEELPLNEYREYIKVQTDKGTEVATNLVILCTGIKINS 249 Query: 401 ELAKTGGLEIDSDFGGFRVNAELQ--ARSNIWVAGDAA 436 + + G RVN LQ SN++ GD A Sbjct: 250 SAYRKAFESRLASSGALRVNEHLQVEGHSNVYAIGDCA 287 >gi|50301238 glutathione reductase [Homo sapiens] Length = 522 Score = 39.7 bits (91), Expect = 0.008 Identities = 87/371 (23%), Positives = 137/371 (36%), Gaps = 60/371 (16%) Query: 100 LTPEQKQKKAALS---ASEGEEVPQDKAPS-----HVPFLLIGGGTAAFAAARSIRARDP 151 L PE ALS A E PQ P+ +L+IGGG+ A+AR RA + Sbjct: 29 LLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASAR--RAAEL 86 Query: 152 GARVLIVSED------------PELPYMRPPLSKELWFSDD----PNVTKTLRFKQWNGK 195 GAR +V P+ + E P+ ++ K Sbjct: 87 GARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEK 146 Query: 196 ERSIYFQPPSFYVSAQDLPHIEN-GGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLI 254 + + + Y + HIE G A T ++V G + T LI Sbjct: 147 RDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEV--------SGKKYTAPHILI 198 Query: 255 ATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACA 314 ATGG P + GA + + G F+ E R V I+G G++ E+A Sbjct: 199 ATGGMPSTPHESQIPGASLGITSD-----GFFQLEELPGRSV----IVGAGYIAVEMAGI 249 Query: 315 LGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGK 374 L ALG++ L + + +S E++ GV+V+ + V+ V + Sbjct: 250 LS----ALGSKT-SLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSG 304 Query: 375 L---LIKLKDGRK------VETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA 425 L ++ GR + D ++ A+G PN + L I +D G + E Q Sbjct: 305 LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQN 364 Query: 426 RS--NIWVAGD 434 + I+ GD Sbjct: 365 TNVKGIYAVGD 375 >gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain 1 [Homo sapiens] Length = 500 Score = 37.7 bits (86), Expect = 0.031 Identities = 48/211 (22%), Positives = 79/211 (37%), Gaps = 42/211 (19%) Query: 125 PSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMR--PPLSKELWFSDDPN 182 P+ F+++GGG A A + P +L+V+ P + + +SK L D Sbjct: 8 PTAGKFVVVGGGIAGVTCAEQLATHFPSEDILLVTASPVIKAVTNFKQISKILEEFDVEE 67 Query: 183 VTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLN 242 + T+ K++ P+ V IE+G V QL ++ + Sbjct: 68 QSSTMLGKRF-----------PNIKV-------IESG---------VKQLKSEEHCIVTE 100 Query: 243 DGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITII 302 DG+Q Y+K + G P+ + E R + +K + K I II Sbjct: 101 DGNQHVYKKLCLCAGAKPKLI-------CEGNPYVLGIRDTDSAQEFQKQLTKAKRIMII 153 Query: 303 GGGFLGSELACALGRKARALGTEVIQLFPEK 333 G G + EL + G EVI +K Sbjct: 154 GNGGIALELVYEIE------GCEVIWAIKDK 178 >gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sapiens] Length = 528 Score = 36.2 bits (82), Expect = 0.090 Identities = 55/251 (21%), Positives = 91/251 (36%), Gaps = 32/251 (12%) Query: 316 GRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRR-----EGVKVMPNAI--VQSV 368 GRK R ++ ++ E + KIL E EK ++ G K + + + +++V Sbjct: 120 GRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTV 179 Query: 369 GVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSN 428 + K + K+ + + +AA + ELA E+D D G ELQ Sbjct: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239 Query: 429 IWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGY 488 + GD A A L+G+ T A Y W+ + Sbjct: 240 LDTDGDGAL--------------SEAEAQALLSGDTQTDATSFY---DRVWAAIRDKYRS 282 Query: 489 EAIGLVDSSLPTVGVFAKATAQDNP-------KSATEQSGTGIRSESETESEASEITIPP 541 EA+ D P+ + + P + E+ +E E E E SE PP Sbjct: 283 EALP-TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPP 341 Query: 542 STPAVPQAPVQ 552 +P P +P + Sbjct: 342 LSPPQPASPAE 352 >gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] Length = 2440 Score = 35.8 bits (81), Expect = 0.12 Identities = 46/182 (25%), Positives = 73/182 (40%), Gaps = 34/182 (18%) Query: 390 IVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVE 449 +V A P ++++KT +S R+ L++RS AA +L ++ +E Sbjct: 1824 LVDAAASAPQMDVSKTK----ESKHEAARLEENLRSRS-------AAVSEQQQLEQKTLE 1872 Query: 450 HHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVG------- 502 +V L + + KP H S+ +S+ G D G + L T G Sbjct: 1873 VEKRSVQC--LYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAA 1930 Query: 503 -----VFAKATAQDNPKSATEQSGTGIRSES-------ETESEASEITIPPSTPAVPQAP 550 + + A D K A E+ S S ET S+A E+ P S+PA PQ Sbjct: 1931 NFIDVIITRQIASD--KDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASSPAPPQEK 1988 Query: 551 VQ 552 +Q Sbjct: 1989 LQ 1990 >gi|65301141 PH domain and leucine rich repeat protein phosphatase-like [Homo sapiens] Length = 1323 Score = 33.5 bits (75), Expect = 0.58 Identities = 19/55 (34%), Positives = 27/55 (49%) Query: 501 VGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGED 555 VG + T +D PK AT S +GI SE +E SE++ + A + G D Sbjct: 1053 VGFASTTTIKDAPKPATPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNAGGLD 1107 >gi|145199237 transcription elongation factor B polypeptide 3 binding protein 1 [Homo sapiens] Length = 1221 Score = 33.1 bits (74), Expect = 0.76 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 506 KATAQDNPKSATEQSGTGIRSESET--ESEASEITIPPSTPAVPQAPVQGEDYG 557 KAT Q K E G G+R ET + + ++ PP+ PA P +D G Sbjct: 316 KATGQPPSKEGLEAEGGGLRETKETAVQCDVGDLQPPPAKPASPAQVQSSQDGG 369 >gi|239747100 PREDICTED: hypothetical protein XP_002344493 [Homo sapiens] Length = 300 Score = 32.7 bits (73), Expect = 1.00 Identities = 17/49 (34%), Positives = 22/49 (44%) Query: 103 EQKQKKAALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDP 151 E+ +++ A SE D PS P + GG AA AA R R P Sbjct: 214 EEAREERARGCSEASRTSSDSGPSRAPAARVVGGEAAATAAARARPRAP 262 >gi|221139926 NHS-like 1 [Homo sapiens] Length = 1606 Score = 31.6 bits (70), Expect = 2.2 Identities = 49/199 (24%), Positives = 76/199 (38%), Gaps = 33/199 (16%) Query: 30 QRNRLPVVQSHHLGSPSRSLASTGASGKDGSNLVYFLIVGATVTGAGVYYAYKTMKEDEK 89 Q R PV +HL PS L S ++ + S A+VT + A + + D Sbjct: 1098 QEQRTPVAPQYHL-KPSAFLKSRNSTNEMESESQ-----PASVTSSLPTPAKSSSQGDHG 1151 Query: 90 RYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRAR 149 ER + +P A SA E E P +PS P + Sbjct: 1152 SAAERGGPVSRSP------GAPSAGEAEARP---SPSTTP----------------LPDS 1186 Query: 150 DPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRF--KQWNGKERSIYFQPPSFY 207 P + +S+ P+L + PP K+ NV++ LR G+E S++ + Sbjct: 1187 SPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKES 1246 Query: 208 VSAQDLPHIENGGVAVLTG 226 +AQ H + G +VL G Sbjct: 1247 SAAQAGSHATHPGTSVLEG 1265 >gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Homo sapiens] Length = 471 Score = 30.8 bits (68), Expect = 3.8 Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 293 SREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMG 337 ++ V IT++GGG LG +AC L A+ + ++ L +G G Sbjct: 179 NKTVNKITVVGGGELG--IACTLAISAKGIADRLVLLDLSEGTKG 221 >gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Homo sapiens] Length = 379 Score = 30.8 bits (68), Expect = 3.8 Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 293 SREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMG 337 ++ V IT++GGG LG +AC L A+ + ++ L +G G Sbjct: 179 NKTVNKITVVGGGELG--IACTLAISAKGIADRLVLLDLSEGTKG 221 >gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8 [Homo sapiens] Length = 1765 Score = 30.4 bits (67), Expect = 4.9 Identities = 13/42 (30%), Positives = 25/42 (59%) Query: 7 LAAGALKQKLVPLVRTVCVRSPRQRNRLPVVQSHHLGSPSRS 48 L G+ +++L+P++ T+ SP ++ +L V +PSRS Sbjct: 1722 LKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENPSRS 1763 >gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo sapiens] Length = 747 Score = 30.0 bits (66), Expect = 6.5 Identities = 17/51 (33%), Positives = 23/51 (45%) Query: 505 AKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGED 555 A+ATA + E+ G G R E E E + + T P A QG+D Sbjct: 132 AEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDD 182 >gi|4503571 enolase 1 [Homo sapiens] Length = 434 Score = 29.6 bits (65), Expect = 8.4 Identities = 47/194 (24%), Positives = 76/194 (39%), Gaps = 36/194 (18%) Query: 240 KLNDGSQITYEKCLIATGGTPRSLS-----------AIDRAGAEVKSRTTLFRKIGDFRS 288 KLN Q +K +I GT A+ +AGA V+ L+R I D Sbjct: 81 KLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGA-VEKGVPLYRHIADLAG 139 Query: 289 LEKISREVKSITII-GGGFLGSELA----------CALGRKARALGTEVIQLFPEKGNMG 337 ++ V + +I GG G++LA A R+A +G EV N+ Sbjct: 140 NSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYH------NLK 193 Query: 338 KILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLE 397 ++ E V EG PN + G+ L+K G+ TD +V + + Sbjct: 194 NVIKEKYGK-DATNVGDEG-GFAPNILENKEGLE----LLKTAIGKAGYTDKVVIGMDVA 247 Query: 398 PNVELAKTGGLEID 411 + E ++G ++D Sbjct: 248 AS-EFFRSGKYDLD 260 >gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sapiens] Length = 525 Score = 29.6 bits (65), Expect = 8.4 Identities = 53/246 (21%), Positives = 87/246 (35%), Gaps = 32/246 (13%) Query: 316 GRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRR-----EGVKVMPNAI--VQSV 368 GRK R ++ ++ E + KIL E EK ++ G K + + + +++V Sbjct: 120 GRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTV 179 Query: 369 GVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSN 428 + K + K+ + + +AA + ELA E+D D G ELQ Sbjct: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239 Query: 429 IWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGY 488 + GD A A L+G+ T A Y W+ + Sbjct: 240 LDTDGDGAL--------------SEAEAQALLSGDTQTDATSFY---DRVWAAIRDKYRS 282 Query: 489 EAIGLVDSSLPTVGVFAKATAQDNP-------KSATEQSGTGIRSESETESEASEITIPP 541 EA+ D P+ + + P + E+ +E E E E SE+ Sbjct: 283 EALP-TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQ 341 Query: 542 STPAVP 547 PA P Sbjct: 342 PKPASP 347 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,102,826 Number of Sequences: 37866 Number of extensions: 1044938 Number of successful extensions: 3495 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 3458 Number of HSP's gapped (non-prelim): 33 length of query: 609 length of database: 18,247,518 effective HSP length: 108 effective length of query: 501 effective length of database: 14,157,990 effective search space: 7093152990 effective search space used: 7093152990 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.