Guide to the Human Genome
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Search of human proteins with 22035700

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035700 synaptogyrin 1 isoform 1c [Homo sapiens]
         (192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035700 synaptogyrin 1 isoform 1c [Homo sapiens]                  397   e-111
gi|22035698 synaptogyrin 1 isoform 1b [Homo sapiens]                  322   2e-88
gi|22035696 synaptogyrin 1 isoform 1a [Homo sapiens]                  272   1e-73
gi|4759202 synaptogyrin 2 [Homo sapiens]                              166   9e-42
gi|6631112 synaptogyrin 3 [Homo sapiens]                              162   1e-40
gi|22035702 synaptogyrin 4 [Homo sapiens]                             125   3e-29
gi|194018518 synaptoporin isoform 1 [Homo sapiens]                     32   0.33 
gi|21389481 synaptoporin isoform 2 [Homo sapiens]                      32   0.33 
gi|61635915 membrane-associated transporter protein isoform a [H...    30   1.3  
gi|61636000 membrane-associated transporter protein isoform b [H...    30   1.3  
gi|31657096 chemokine-like factor superfamily 4 isoform 2 [Homo ...    30   1.3  
gi|30520333 chemokine-like factor superfamily 4 isoform 1 [Homo ...    30   1.3  
gi|122937337 fat storage-inducing transmembrane protein 2 [Homo ...    30   1.6  
gi|21729876 ATP-binding cassette, sub-family C, member 11 isofor...    28   4.8  
gi|21729873 ATP-binding cassette, sub-family C, member 11 isofor...    28   4.8  
gi|15149474 ATP-binding cassette, sub-family C, member 11 isofor...    28   4.8  
gi|53828683 olfactory receptor, family 52, subfamily B, member 2...    28   4.8  
gi|6005701 ATP-binding cassette, sub-family A member 8 [Homo sap...    28   6.3  

>gi|22035700 synaptogyrin 1 isoform 1c [Homo sapiens]
          Length = 192

 Score =  397 bits (1020), Expect = e-111
 Identities = 192/192 (100%), Positives = 192/192 (100%)

Query: 1   MLTLEFGILEFDPSWIGSWTQRSWVSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFC 60
           MLTLEFGILEFDPSWIGSWTQRSWVSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFC
Sbjct: 1   MLTLEFGILEFDPSWIGSWTQRSWVSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFC 60

Query: 61  IYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLW 120
           IYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLW
Sbjct: 61  IYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLW 120

Query: 121 FVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQE 180
           FVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQE
Sbjct: 121 FVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQE 180

Query: 181 EYSTLFPASAQP 192
           EYSTLFPASAQP
Sbjct: 181 EYSTLFPASAQP 192


>gi|22035698 synaptogyrin 1 isoform 1b [Homo sapiens]
          Length = 191

 Score =  322 bits (824), Expect = 2e-88
 Identities = 161/168 (95%), Positives = 161/168 (95%), Gaps = 7/168 (4%)

Query: 25  VSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL 84
           VSW       LFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL
Sbjct: 31  VSW-------LFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL 83

Query: 85  LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEG 144
           LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEG
Sbjct: 84  LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEG 143

Query: 145 TDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQEEYSTLFPASAQP 192
           TDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQEEYSTLFPASAQP
Sbjct: 144 TDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQEEYSTLFPASAQP 191


>gi|22035696 synaptogyrin 1 isoform 1a [Homo sapiens]
          Length = 233

 Score =  272 bits (696), Expect = 1e-73
 Identities = 139/172 (80%), Positives = 146/172 (84%), Gaps = 11/172 (6%)

Query: 25  VSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL 84
           VSW       LFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL
Sbjct: 31  VSW-------LFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL 83

Query: 85  LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEG 144
           LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEG
Sbjct: 84  LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEG 143

Query: 145 TDAARAAIAFSFFSIFTWSLTAALAVRRFK----DLSFQEEYSTLFPASAQP 192
           TDAARAAIAFSFFSIFTW+  A LA +R++       F ++Y      S+ P
Sbjct: 144 TDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMP 195


>gi|4759202 synaptogyrin 2 [Homo sapiens]
          Length = 224

 Score =  166 bits (421), Expect = 9e-42
 Identities = 76/146 (52%), Positives = 102/146 (69%), Gaps = 2/146 (1%)

Query: 29  SRPGCELFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLA 88
           +R  C +F+++VF  I  EGY N+    + +C++NRN +AC YG A+GVLAFL    +L 
Sbjct: 28  ARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLV 87

Query: 89  LDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAA 148
           +D YFPQIS+  DRK  V+ D+  SA W FLWFVGFC+L NQW V+ PKD  +  G D+ 
Sbjct: 88  VDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKD--VLVGADSV 145

Query: 149 RAAIAFSFFSIFTWSLTAALAVRRFK 174
           RAAI FSFFSIF+W + A+LA +R+K
Sbjct: 146 RAAITFSFFSIFSWGVLASLAYQRYK 171


>gi|6631112 synaptogyrin 3 [Homo sapiens]
          Length = 229

 Score =  162 bits (411), Expect = 1e-40
 Identities = 80/140 (57%), Positives = 100/140 (71%), Gaps = 1/140 (0%)

Query: 35  LFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFP 94
           +FSI VFG IVNEGY+N+ S  E  C++N N  AC +GVA+G+ AFL C  +L LDV F 
Sbjct: 34  VFSIAVFGPIVNEGYVNTDSGPELRCVFNGNAGACRFGVALGLGAFLACAAFLLLDVRFQ 93

Query: 95  QISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAF 154
           QISSV+DR++AVL D+G S  W+FLWFVGFC+L NQWQ + P       G DAARAAIAF
Sbjct: 94  QISSVRDRRRAVLLDLGFSGLWSFLWFVGFCFLTNQWQRTAPGPATTQAG-DAARAAIAF 152

Query: 155 SFFSIFTWSLTAALAVRRFK 174
           SFFSI +W      A++RF+
Sbjct: 153 SFFSILSWVALTVKALQRFR 172


>gi|22035702 synaptogyrin 4 [Homo sapiens]
          Length = 234

 Score =  125 bits (313), Expect = 3e-29
 Identities = 64/142 (45%), Positives = 89/142 (62%), Gaps = 5/142 (3%)

Query: 35  LFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFP 94
           +FS++VF S++ +GY N     +  CI N N  ACS+ V  G LAFL+CL +L LD    
Sbjct: 32  VFSLIVFSSLLTDGYQNKMESPQLHCILNSNSVACSFAVGAGFLAFLSCLAFLVLDTQET 91

Query: 95  QISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAF 154
           +I+  + +    L D  ++  WA +WF+GFC+LANQWQ S PK+  L  G+ +A+AAIAF
Sbjct: 92  RIAGTRFKTAFQLLDFILAVLWAVVWFMGFCFLANQWQHSPPKEFLL--GSSSAQAAIAF 149

Query: 155 SFFSIFTWSLTAALAVRRFKDL 176
           +FFSI  W   A LA   F+DL
Sbjct: 150 TFFSILVWIFQAYLA---FQDL 168


>gi|194018518 synaptoporin isoform 1 [Homo sapiens]
          Length = 285

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 55  EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA 114
           E ++  +   + ++  + V V V AFL  L    + ++F   +  ++  +  L D  V+ 
Sbjct: 85  ERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQ--NKYRENNRGPLIDFIVTV 142

Query: 115 FWAFLWFVG 123
            ++FLW VG
Sbjct: 143 VFSFLWLVG 151


>gi|21389481 synaptoporin isoform 2 [Homo sapiens]
          Length = 265

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 55  EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA 114
           E ++  +   + ++  + V V V AFL  L    + ++F   +  ++  +  L D  V+ 
Sbjct: 65  ERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQ--NKYRENNRGPLIDFIVTV 122

Query: 115 FWAFLWFVG 123
            ++FLW VG
Sbjct: 123 VFSFLWLVG 131


>gi|61635915 membrane-associated transporter protein isoform a [Homo
           sapiens]
          Length = 530

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 20/100 (20%)

Query: 25  VSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL 84
           + W +     LF     G IV  G   SA    EF IY R       GV VG   F    
Sbjct: 326 IGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYER-------GVEVGCWGFCINS 378

Query: 85  LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGF 124
           ++ +L  YF         +K ++S IG+      L+F G+
Sbjct: 379 VFSSLYSYF---------QKVLVSYIGLKG----LYFTGY 405


>gi|61636000 membrane-associated transporter protein isoform b [Homo
           sapiens]
          Length = 460

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 20/100 (20%)

Query: 25  VSWRSRPGCELFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCL 84
           + W +     LF     G IV  G   SA    EF IY R       GV VG   F    
Sbjct: 326 IGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYER-------GVEVGCWGFCINS 378

Query: 85  LYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGF 124
           ++ +L  YF         +K ++S IG+      L+F G+
Sbjct: 379 VFSSLYSYF---------QKVLVSYIGLKG----LYFTGY 405


>gi|31657096 chemokine-like factor superfamily 4 isoform 2 [Homo
           sapiens]
          Length = 208

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 21/107 (19%)

Query: 68  ACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYL 127
           +CS  V  GVL  +     L L +  PQI+         L+D+  +   AFL+F+    L
Sbjct: 91  SCSAFVVTGVLLIM---FSLNLHMRIPQINWN-------LTDLVNTGLSAFLFFIASIVL 140

Query: 128 ANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFK 174
           A            LN    A  AA+ F F +   +++   LAV++++
Sbjct: 141 A-----------ALNHRAGAEIAAVIFGFLATAAYAVNTFLAVQKWR 176


>gi|30520333 chemokine-like factor superfamily 4 isoform 1 [Homo
           sapiens]
          Length = 234

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 21/107 (19%)

Query: 68  ACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYL 127
           +CS  V  GVL  +     L L +  PQI+         L+D+  +   AFL+F+    L
Sbjct: 91  SCSAFVVTGVLLIM---FSLNLHMRIPQINWN-------LTDLVNTGLSAFLFFIASIVL 140

Query: 128 ANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFK 174
           A            LN    A  AA+ F F +   +++   LAV++++
Sbjct: 141 A-----------ALNHRAGAEIAAVIFGFLATAAYAVNTFLAVQKWR 176


>gi|122937337 fat storage-inducing transmembrane protein 2 [Homo
           sapiens]
          Length = 262

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 73  VAVGVLAFLTCLLYLALDVYFPQIS-SVKDRKKAVLSDIGVSAFW 116
           VA+G+L F+  L++L   VYF  +S  V      +LS  G   FW
Sbjct: 193 VALGILTFIWVLMFLCTAVYFHNLSQKVFGTLFGLLSWYGTYGFW 237


>gi|21729876 ATP-binding cassette, sub-family C, member 11 isoform b
           [Homo sapiens]
          Length = 1344

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%)

Query: 9   LEFDPSWIGSWTQRSWVSWRSRPGCELFS-IVVFGSIVNEGYLNSASEGEEFCIYNRNPN 67
           L F  SWI +  QR+ + +R+      F  ++ F S+++       + GE    +  + N
Sbjct: 218 LSFSSSWIIN--QRTAIRFRAAVSSFAFEKLIQFKSVIH------ITSGEAISFFTGDVN 269

Query: 68  ACSYGVAVGVLAFLTC--LLYLALDVYF 93
               GV  G L  +TC  L+  ++  YF
Sbjct: 270 YLFEGVCYGPLVLITCASLVICSISSYF 297


>gi|21729873 ATP-binding cassette, sub-family C, member 11 isoform a
           [Homo sapiens]
          Length = 1382

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%)

Query: 9   LEFDPSWIGSWTQRSWVSWRSRPGCELFS-IVVFGSIVNEGYLNSASEGEEFCIYNRNPN 67
           L F  SWI +  QR+ + +R+      F  ++ F S+++       + GE    +  + N
Sbjct: 218 LSFSSSWIIN--QRTAIRFRAAVSSFAFEKLIQFKSVIH------ITSGEAISFFTGDVN 269

Query: 68  ACSYGVAVGVLAFLTC--LLYLALDVYF 93
               GV  G L  +TC  L+  ++  YF
Sbjct: 270 YLFEGVCYGPLVLITCASLVICSISSYF 297


>gi|15149474 ATP-binding cassette, sub-family C, member 11 isoform a
           [Homo sapiens]
          Length = 1382

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%)

Query: 9   LEFDPSWIGSWTQRSWVSWRSRPGCELFS-IVVFGSIVNEGYLNSASEGEEFCIYNRNPN 67
           L F  SWI +  QR+ + +R+      F  ++ F S+++       + GE    +  + N
Sbjct: 218 LSFSSSWIIN--QRTAIRFRAAVSSFAFEKLIQFKSVIH------ITSGEAISFFTGDVN 269

Query: 68  ACSYGVAVGVLAFLTC--LLYLALDVYF 93
               GV  G L  +TC  L+  ++  YF
Sbjct: 270 YLFEGVCYGPLVLITCASLVICSISSYF 297


>gi|53828683 olfactory receptor, family 52, subfamily B, member 2
           [Homo sapiens]
          Length = 323

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)

Query: 127 LANQWQVSKPKDNPLNEG--TDAARAAIAFSFFSIFTWSLTAAL 168
           LAN +    P  NP+  G  T   R  +A  FF I TW  T+ L
Sbjct: 278 LANLYVAVPPMLNPIVYGVKTKQIREGVAHRFFDIKTWCCTSPL 321


>gi|6005701 ATP-binding cassette, sub-family A member 8 [Homo
           sapiens]
          Length = 1581

 Score = 27.7 bits (60), Expect = 6.3
 Identities = 15/56 (26%), Positives = 33/56 (58%), Gaps = 6/56 (10%)

Query: 78  LAFLTCLLYLALDVYFPQISSVKDRK--KAVLSDIGV--SAFWAF--LWFVGFCYL 127
           L   +C++  +  +Y+  ++  ++RK  KA+++ +G+  SAFW    L + GF ++
Sbjct: 224 LYLFSCIISFSSFIYYASVNVTRERKRMKALMTMMGLRDSAFWLSWGLLYAGFIFI 279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,211,435
Number of Sequences: 37866
Number of extensions: 271757
Number of successful extensions: 681
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 670
Number of HSP's gapped (non-prelim): 20
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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