Guide to the Human Genome
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Search of human proteins with 115305569

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115305569 adenosine A1 receptor [Homo sapiens]
         (326 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115305569 adenosine A1 receptor [Homo sapiens]                     655   0.0  
gi|4501947 adenosine A1 receptor [Homo sapiens]                       655   0.0  
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]             301   4e-82
gi|5921992 adenosine A2a receptor [Homo sapiens]                      301   7e-82
gi|4501951 adenosine A2b receptor [Homo sapiens]                      270   2e-72
gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens]            123   2e-28
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]           122   4e-28
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]            122   4e-28
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]        115   4e-26
gi|4503383 dopamine receptor D1 [Homo sapiens]                        115   7e-26
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]         114   9e-26
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]         114   9e-26
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]         114   9e-26
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]         114   9e-26
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]         114   9e-26
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]         114   9e-26
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    112   3e-25
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    112   3e-25
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]    112   3e-25
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]    112   3e-25
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                109   3e-24
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                108   5e-24
gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sap...   107   1e-23
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           106   2e-23
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           106   2e-23
gi|4503391 dopamine receptor D5 [Homo sapiens]                        104   1e-22
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]      102   4e-22
gi|222080095 orexin receptor 1 [Homo sapiens]                         102   5e-22
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...   100   2e-21
gi|5174535 melanocortin 5 receptor [Homo sapiens]                      99   4e-21

>gi|115305569 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score =  655 bits (1689), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60
           MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
Sbjct: 1   MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60

Query: 61  LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT 120
           LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
Sbjct: 61  LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT 120

Query: 121 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM 180
           PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
Sbjct: 121 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM 180

Query: 181 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL 240
           VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
Sbjct: 181 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL 240

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
           FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
Sbjct: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300

Query: 301 KIWNDHFRCQPAPPIDEDLPEERPDD 326
           KIWNDHFRCQPAPPIDEDLPEERPDD
Sbjct: 301 KIWNDHFRCQPAPPIDEDLPEERPDD 326


>gi|4501947 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score =  655 bits (1689), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60
           MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
Sbjct: 1   MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60

Query: 61  LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT 120
           LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
Sbjct: 61  LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT 120

Query: 121 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM 180
           PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
Sbjct: 121 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM 180

Query: 181 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL 240
           VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
Sbjct: 181 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL 240

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
           FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
Sbjct: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300

Query: 301 KIWNDHFRCQPAPPIDEDLPEERPDD 326
           KIWNDHFRCQPAPPIDEDLPEERPDD
Sbjct: 301 KIWNDHFRCQPAPPIDEDLPEERPDD 326


>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
          Length = 318

 Score =  301 bits (772), Expect = 4e-82
 Identities = 153/316 (48%), Positives = 217/316 (68%), Gaps = 9/316 (2%)

Query: 4   SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVI 63
           ++S     YI +E+ I L ++ GNVLVI  VK+N +L+  TF FIVSLA+AD+AVG LV+
Sbjct: 7   ALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVM 66

Query: 64  PLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 123
           PLAI++++G   +F++CL + C +LI T +SI++LLAIAVDRYLRVK+ +RYK V T RR
Sbjct: 67  PLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRR 126

Query: 124 AAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183
             +A+  CW++SF+VGLTPMFGWN     E             + C+F  V+ M+YMVYF
Sbjct: 127 IWLALGLCWLVSFLVGLTPMFGWNMKLTSEY------HRNVTFLSCQFVSVMRMDYMVYF 180

Query: 184 NFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLF 243
           +F  W+  PL++M  IYL++FY+IR +L+  +S +S +   +YG+E K AKSL L+LFLF
Sbjct: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLS-NSKETGAFYGREFKTAKSLFLVLFLF 239

Query: 244 ALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIW 303
           ALSWLPL I+NCI  F  +   P ++ Y+ I L+H NS MNPIVYA++I+KF+ T+L I 
Sbjct: 240 ALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297

Query: 304 NDHFRCQPAPPIDEDL 319
                C P+  +D  +
Sbjct: 298 KACVVCHPSDSLDTSI 313


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score =  301 bits (770), Expect = 7e-82
 Identities = 158/307 (51%), Positives = 202/307 (65%), Gaps = 3/307 (0%)

Query: 10  AAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILI 69
           + YI +E+ IA++++ GNVLV WAV +N  L++ T  F+VSLA AD+AVG L IP AI I
Sbjct: 7   SVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITI 66

Query: 70  NIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIA 129
           + G     H CL +AC VL+LTQSSI +LLAIA+DRY+ ++IPLRY  +VT  RA   IA
Sbjct: 67  STGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIA 126

Query: 130 GCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWV 189
            CW+LSF +GLTPM GWNN    +     +   GE  + C FE V+ M YMVYFNFF  V
Sbjct: 127 ICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACV 186

Query: 190 LPPLLLMVLIYLEVFYLIRKQLNKKVS--ASSGDPQKYYGKELKIAKSLALILFLFALSW 247
           L PLLLM+ +YL +F   R+QL +  S        +    KE+  AKSLA+I+ LFAL W
Sbjct: 187 LVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCW 246

Query: 248 LPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDH 306
           LPLHI+NC T FCP C H P  L Y+AI L+H NS +NP +YA+RI++FR TF KI   H
Sbjct: 247 LPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSH 306

Query: 307 FRCQPAP 313
              Q  P
Sbjct: 307 VLRQQEP 313


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score =  270 bits (689), Expect = 2e-72
 Identities = 147/307 (47%), Positives = 201/307 (65%), Gaps = 8/307 (2%)

Query: 10  AAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILI 69
           A Y+ +E++IA +SV GNVLV  AV     L+  T  F+VSLA ADVAVG   IP AI I
Sbjct: 8   ALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITI 67

Query: 70  NIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIA 129
           ++G  T F+ CL +AC VL+LTQSSI +LLA+AVDRYL + +PLRYK +VT  RA   IA
Sbjct: 68  SLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIA 127

Query: 130 GCWILSFVVGLTPMFGWNNLSAV----ERAWAANGSMGEPVIKCEFEKVISMEYMVYFNF 185
             W+L+F +GLTP  GWN+  +        W    +    ++KC FE V+ M YMVYFNF
Sbjct: 128 VLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNF 187

Query: 186 FVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFAL 245
           F  VLPPLL+M++IY+++F +  +QL +  +      +    +E+  AKSLA+I+ +FAL
Sbjct: 188 FGCVLPPLLIMLVIYIKIFLVACRQLQR--TELMDHSRTTLQREIHAAKSLAMIVGIFAL 245

Query: 246 SWLPLHILNCITLFCPS--CHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIW 303
            WLP+H +NC+TLF P+   +KP     +AI L+H NS +NPIVYA+R + FR TF KI 
Sbjct: 246 CWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKII 305

Query: 304 NDHFRCQ 310
           + +  CQ
Sbjct: 306 SRYLLCQ 312


>gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens]
          Length = 347

 Score =  123 bits (309), Expect = 2e-28
 Identities = 66/133 (49%), Positives = 95/133 (71%), Gaps = 9/133 (6%)

Query: 4   SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVI 63
           ++S     YI +E+ I L ++ GNVLVI  VK+N +L+  TF FIVSLA+AD+AVG LV+
Sbjct: 7   ALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVM 66

Query: 64  PLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 123
           PLAI++++G   +F++CL + C +LI T +SI++LLAIAVDRYLRVK+ +R+++   P  
Sbjct: 67  PLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLP-- 124

Query: 124 AAVAIAGCWILSF 136
                 GC ILSF
Sbjct: 125 ------GC-ILSF 130


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score =  122 bits (306), Expect = 4e-28
 Identities = 92/300 (30%), Positives = 148/300 (49%), Gaps = 18/300 (6%)

Query: 10  AAYIGIEVLIA---LVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLA 66
           A  I I V++A   L++V GNV+V  AV +N+ LR+ T CFIVSLA+ D+ +G LV+P +
Sbjct: 16  ACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFS 75

Query: 67  ILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRA 124
            +  +  +  F    C +     ++L  +SIL L  I++DRY  V  PLRY ++VTP R 
Sbjct: 76  AIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRV 135

Query: 125 AVAIAGCWILSFVVG-LTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183
           A+++   W++S  +  L+   GWN+ +   +             KC   KV   E     
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNSRNETSKG-------NHTTSKC---KVQVNEVYGLV 185

Query: 184 NFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLF 243
           +  V    PLL+M + Y  +F + R Q  +    SS        +E K   +LA ++  F
Sbjct: 186 DGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATI--REHKATVTLAAVMGAF 243

Query: 244 ALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIW 303
            + W P                  +L  I ++L + NSA+NPI+YA   + FR  + +++
Sbjct: 244 IICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLF 303


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score =  122 bits (306), Expect = 4e-28
 Identities = 92/300 (30%), Positives = 148/300 (49%), Gaps = 18/300 (6%)

Query: 10  AAYIGIEVLIA---LVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLA 66
           A  I I V++A   L++V GNV+V  AV +N+ LR+ T CFIVSLA+ D+ +G LV+P +
Sbjct: 16  ACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFS 75

Query: 67  ILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRA 124
            +  +  +  F    C +     ++L  +SIL L  I++DRY  V  PLRY ++VTP R 
Sbjct: 76  AIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRV 135

Query: 125 AVAIAGCWILSFVVG-LTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183
           A+++   W++S  +  L+   GWN+ +   +             KC   KV   E     
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNSRNETSKG-------NHTTSKC---KVQVNEVYGLV 185

Query: 184 NFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLF 243
           +  V    PLL+M + Y  +F + R Q  +    SS        +E K   +LA ++  F
Sbjct: 186 DGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATI--REHKATVTLAAVMGAF 243

Query: 244 ALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIW 303
            + W P                  +L  I ++L + NSA+NPI+YA   + FR  + +++
Sbjct: 244 IICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLF 303


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score =  115 bits (289), Expect = 4e-26
 Identities = 93/313 (29%), Positives = 153/313 (48%), Gaps = 30/313 (9%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGE---PVIKCEFEKVISMEYMVYFNFFVWVL 190
            +F+  L  M GWNN+  ++   + N  +G+    + K +F +  +  Y V+     + +
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKPYAI 208

Query: 191 P--------PLLLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKE 229
                    P LLMVL Y  ++   +      + L +  ++S   PQ            E
Sbjct: 209 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTE 268

Query: 230 LKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYA 289
            K AK+L +I+  F L W P  + N +  F        + T   ++L + NS +NP +YA
Sbjct: 269 TKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYA 327

Query: 290 FRIQKFRVTFLKI 302
           F  + FR  FL I
Sbjct: 328 FLNKSFRRAFLII 340


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score =  115 bits (287), Expect = 7e-26
 Identities = 89/329 (27%), Positives = 156/329 (47%), Gaps = 41/329 (12%)

Query: 4   SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRD-ATFCFIVSLAVADVAVGALV 62
           S+    A ++ + +L  L+   GN LV  AV   + LR   T  F++SLAV+D+ V  LV
Sbjct: 21  SVRILTACFLSLLILSTLL---GNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLV 77

Query: 63  IPLAILINI-GPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTP 121
           +P   +  I G   +   C +     ++ + +SIL L  I+VDRY  +  P RY+  +TP
Sbjct: 78  MPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTP 137

Query: 122 RRAAVAIAGCWILSFVVGLTPM-FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM 180
           + A + I+  W LS ++   P+   W+       +     S+ E +  C  +  +S  Y 
Sbjct: 138 KAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNC--DSSLSRTYA 195

Query: 181 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQL--------------NKKVSASSGDP---- 222
           +  +   + + P+ +M++ Y  ++ + +KQ+              N + +  +G P    
Sbjct: 196 ISSSVISFYI-PVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECS 254

Query: 223 ------QKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC------PSCHKPSILT 270
                 +  + +E K+ K+L++I+ +F   WLP  ILNCI  FC      P C   +   
Sbjct: 255 QPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFD 314

Query: 271 YIAIFLTHGNSAMNPIVYAFRIQKFRVTF 299
            + ++    NS++NPI+YAF    FR  F
Sbjct: 315 -VFVWFGWANSSLNPIIYAFNAD-FRKAF 341


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score =  114 bits (286), Expect = 9e-26
 Identities = 90/302 (29%), Positives = 148/302 (49%), Gaps = 22/302 (7%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
            +F+  L  M GWNN+  ++       +       C F  +++  Y +  +   + + P 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKPYAITCSVVAFYI-PF 205

Query: 194 LLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKELKIAKSLALIL 240
           LLMVL Y  ++   +      + L +  ++S   PQ            E K AK+L +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
             F L W P  + N +  F        + T   ++L + NS +NP +YAF  + FR  FL
Sbjct: 266 GCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFL 324

Query: 301 KI 302
            I
Sbjct: 325 II 326


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score =  114 bits (286), Expect = 9e-26
 Identities = 90/302 (29%), Positives = 148/302 (49%), Gaps = 22/302 (7%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
            +F+  L  M GWNN+  ++       +       C F  +++  Y +  +   + + P 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKPYAITCSVVAFYI-PF 205

Query: 194 LLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKELKIAKSLALIL 240
           LLMVL Y  ++   +      + L +  ++S   PQ            E K AK+L +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
             F L W P  + N +  F        + T   ++L + NS +NP +YAF  + FR  FL
Sbjct: 266 GCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFL 324

Query: 301 KI 302
            I
Sbjct: 325 II 326


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score =  114 bits (286), Expect = 9e-26
 Identities = 90/302 (29%), Positives = 148/302 (49%), Gaps = 22/302 (7%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
            +F+  L  M GWNN+  ++       +       C F  +++  Y +  +   + + P 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKPYAITCSVVAFYI-PF 205

Query: 194 LLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKELKIAKSLALIL 240
           LLMVL Y  ++   +      + L +  ++S   PQ            E K AK+L +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
             F L W P  + N +  F        + T   ++L + NS +NP +YAF  + FR  FL
Sbjct: 266 GCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFL 324

Query: 301 KI 302
            I
Sbjct: 325 II 326


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score =  114 bits (286), Expect = 9e-26
 Identities = 90/302 (29%), Positives = 148/302 (49%), Gaps = 22/302 (7%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
            +F+  L  M GWNN+  ++       +       C F  +++  Y +  +   + + P 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKPYAITCSVVAFYI-PF 205

Query: 194 LLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKELKIAKSLALIL 240
           LLMVL Y  ++   +      + L +  ++S   PQ            E K AK+L +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
             F L W P  + N +  F        + T   ++L + NS +NP +YAF  + FR  FL
Sbjct: 266 GCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFL 324

Query: 301 KI 302
            I
Sbjct: 325 II 326


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score =  114 bits (286), Expect = 9e-26
 Identities = 90/302 (29%), Positives = 148/302 (49%), Gaps = 22/302 (7%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
            +F+  L  M GWNN+  ++       +       C F  +++  Y +  +   + + P 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKPYAITCSVVAFYI-PF 205

Query: 194 LLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKELKIAKSLALIL 240
           LLMVL Y  ++   +      + L +  ++S   PQ            E K AK+L +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
             F L W P  + N +  F        + T   ++L + NS +NP +YAF  + FR  FL
Sbjct: 266 GCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFL 324

Query: 301 KI 302
            I
Sbjct: 325 II 326


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score =  114 bits (286), Expect = 9e-26
 Identities = 90/302 (29%), Positives = 148/302 (49%), Gaps = 22/302 (7%)

Query: 19  IALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVGALVIPLAILINIGPQTYF 77
           + L+++ GN+LV+ AV  ++ LR   T  FIVSLA AD+ V  LV+P   +  +     +
Sbjct: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY 88

Query: 78  HT--CLMVACPVLILTQSSILALLAIAVDRYLRVKI-PLRYKMVVTPRRAAVAIAGCWIL 134
               CL+     ++LT +SI  L  I++DRY  +   PL Y+  +TP R A+ + GCW++
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 -SFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
            +F+  L  M GWNN+  ++       +       C F  +++  Y +  +   + + P 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKPYAITCSVVAFYI-PF 205

Query: 194 LLMVLIYLEVFYLIR------KQLNKKVSASSGDPQK-------YYGKELKIAKSLALIL 240
           LLMVL Y  ++   +      + L +  ++S   PQ            E K AK+L +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 241 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL 300
             F L W P  + N +  F        + T   ++L + NS +NP +YAF  + FR  FL
Sbjct: 266 GCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFL 324

Query: 301 KI 302
            I
Sbjct: 325 II 326


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  112 bits (281), Expect = 3e-25
 Identities = 85/346 (24%), Positives = 156/346 (45%), Gaps = 52/346 (15%)

Query: 2   PPSISAFQAAYIGIEVL-IALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60
           P  ++  +A  +G+ +  + L  V GN+LVI +V  ++ L   T  +IV+LAVAD+ + +
Sbjct: 18  PAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77

Query: 61  LVIPLAILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMV 118
            V+P + +  +     F    C + A   ++   +SI+ L  I++DRY+ V  PLRY  +
Sbjct: 78  TVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTI 137

Query: 119 VTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME 178
           VT RR  +A+   W LS V+ + P+FGW   +             E    C+  +     
Sbjct: 138 VTQRRGLMALLCVWALSLVISIGPLFGWRQPAP------------EDETICQINE--EPG 183

Query: 179 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQ---LNKKVSASSGDPQKY---------- 225
           Y+++     + L PL +++++Y  V+ + +++   L   +     D ++           
Sbjct: 184 YVLFSALGSFYL-PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242

Query: 226 ---------------------YGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCH 264
                                + +E K AK+L +++  F L WLP  ++  I  F P   
Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302

Query: 265 KPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQ 310
               +  I  +L + NS +NPI+Y    Q+F+  F  +      C+
Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCR 348


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  112 bits (281), Expect = 3e-25
 Identities = 85/346 (24%), Positives = 156/346 (45%), Gaps = 52/346 (15%)

Query: 2   PPSISAFQAAYIGIEVL-IALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60
           P  ++  +A  +G+ +  + L  V GN+LVI +V  ++ L   T  +IV+LAVAD+ + +
Sbjct: 18  PAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77

Query: 61  LVIPLAILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMV 118
            V+P + +  +     F    C + A   ++   +SI+ L  I++DRY+ V  PLRY  +
Sbjct: 78  TVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTI 137

Query: 119 VTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME 178
           VT RR  +A+   W LS V+ + P+FGW   +             E    C+  +     
Sbjct: 138 VTQRRGLMALLCVWALSLVISIGPLFGWRQPAP------------EDETICQINE--EPG 183

Query: 179 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQ---LNKKVSASSGDPQKY---------- 225
           Y+++     + L PL +++++Y  V+ + +++   L   +     D ++           
Sbjct: 184 YVLFSALGSFYL-PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242

Query: 226 ---------------------YGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCH 264
                                + +E K AK+L +++  F L WLP  ++  I  F P   
Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302

Query: 265 KPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQ 310
               +  I  +L + NS +NPI+Y    Q+F+  F  +      C+
Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCR 348


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score =  112 bits (281), Expect = 3e-25
 Identities = 85/346 (24%), Positives = 156/346 (45%), Gaps = 52/346 (15%)

Query: 2   PPSISAFQAAYIGIEVL-IALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60
           P  ++  +A  +G+ +  + L  V GN+LVI +V  ++ L   T  +IV+LAVAD+ + +
Sbjct: 18  PAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77

Query: 61  LVIPLAILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMV 118
            V+P + +  +     F    C + A   ++   +SI+ L  I++DRY+ V  PLRY  +
Sbjct: 78  TVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTI 137

Query: 119 VTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME 178
           VT RR  +A+   W LS V+ + P+FGW   +             E    C+  +     
Sbjct: 138 VTQRRGLMALLCVWALSLVISIGPLFGWRQPAP------------EDETICQINE--EPG 183

Query: 179 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQ---LNKKVSASSGDPQKY---------- 225
           Y+++     + L PL +++++Y  V+ + +++   L   +     D ++           
Sbjct: 184 YVLFSALGSFYL-PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242

Query: 226 ---------------------YGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCH 264
                                + +E K AK+L +++  F L WLP  ++  I  F P   
Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302

Query: 265 KPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQ 310
               +  I  +L + NS +NPI+Y    Q+F+  F  +      C+
Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCR 348


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score =  112 bits (281), Expect = 3e-25
 Identities = 85/346 (24%), Positives = 156/346 (45%), Gaps = 52/346 (15%)

Query: 2   PPSISAFQAAYIGIEVL-IALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60
           P  ++  +A  +G+ +  + L  V GN+LVI +V  ++ L   T  +IV+LAVAD+ + +
Sbjct: 18  PAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77

Query: 61  LVIPLAILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMV 118
            V+P + +  +     F    C + A   ++   +SI+ L  I++DRY+ V  PLRY  +
Sbjct: 78  TVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTI 137

Query: 119 VTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME 178
           VT RR  +A+   W LS V+ + P+FGW   +             E    C+  +     
Sbjct: 138 VTQRRGLMALLCVWALSLVISIGPLFGWRQPAP------------EDETICQINE--EPG 183

Query: 179 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQ---LNKKVSASSGDPQKY---------- 225
           Y+++     + L PL +++++Y  V+ + +++   L   +     D ++           
Sbjct: 184 YVLFSALGSFYL-PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAP 242

Query: 226 ---------------------YGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCH 264
                                + +E K AK+L +++  F L WLP  ++  I  F P   
Sbjct: 243 AGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK 302

Query: 265 KPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQ 310
               +  I  +L + NS +NPI+Y    Q+F+  F  +      C+
Sbjct: 303 PSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCR 348


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  109 bits (273), Expect = 3e-24
 Identities = 85/342 (24%), Positives = 157/342 (45%), Gaps = 59/342 (17%)

Query: 3   PSISAFQAAYIGIEV-LIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGAL 61
           P +   +A  +G+ +    L ++ GN+LVI +V  N+ LR  T  FIV+LA+AD+ +   
Sbjct: 38  PQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFT 97

Query: 62  VIPLAILINIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVV 119
           V+P +  + +          C + A   ++   +SIL+L AI++DRY+ V+  L+Y  +V
Sbjct: 98  VLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLV 157

Query: 120 TPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME- 178
           T R+A +A+   W+LS V+ + P+ GW                 EP    + E  ++ E 
Sbjct: 158 TRRKAILALLSVWVLSTVISIGPLLGWK----------------EPAPNDDKECGVTEEP 201

Query: 179 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKV----------------------- 215
           +   F+       PL +++++Y  V Y++ K+  K +                       
Sbjct: 202 FYALFSSLGSFYIPLAVILVMYCRV-YIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNF 260

Query: 216 --------SASSGDPQK-------YYGKELKIAKSLALILFLFALSWLPLHILNCITLFC 260
                    A   +P+         + +E K AK+L +++ +F L WLP  I   +    
Sbjct: 261 HEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLF 320

Query: 261 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKI 302
            +   P  +  +  +L + NS +NPI+Y    ++F+  F++I
Sbjct: 321 STLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRI 362


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score =  108 bits (271), Expect = 5e-24
 Identities = 96/346 (27%), Positives = 162/346 (46%), Gaps = 70/346 (20%)

Query: 13  IGIEVLIA---LVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILI 69
           +G+ V +A   L++V GN+LVI +V  N+ L+  T  FIV+LAVAD+ + A V+P +  +
Sbjct: 97  VGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATM 156

Query: 70  NIGPQTYFHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVA 127
            +     F    C + A   ++   +SIL+L  I+VDRY+ V+  L+Y  ++T R+AA  
Sbjct: 157 EVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAI 216

Query: 128 IAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME--YMVYFNF 185
           +A  W+++ VV + P+ GW                 EPV   E    I+ E  Y V+ + 
Sbjct: 217 LALLWVVALVVSVGPLLGWK----------------EPVPPDERFCGITEEAGYAVFSSV 260

Query: 186 FVWVLPPLLLMVLIYLEVFYLIR---KQLNKKVSASSGDPQKY----------------- 225
             + L P+ ++V++Y  V+ + R   + L   V    G   +                  
Sbjct: 261 CSFYL-PMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAH 319

Query: 226 --------------------YGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHK 265
                               + +E K AK+LA+++ +F L W P   +  +    P   K
Sbjct: 320 GMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQL-K 378

Query: 266 PSILTYIAIF-LTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQ 310
           PS   +  IF L + NS +NP++Y    ++F+  FL++     RCQ
Sbjct: 379 PSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRL----LRCQ 420


>gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo
           sapiens]
          Length = 458

 Score =  107 bits (267), Expect = 1e-23
 Identities = 88/351 (25%), Positives = 159/351 (45%), Gaps = 68/351 (19%)

Query: 17  VLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTY 76
           V+I ++++ GN+LVI AV + + L +AT  F++SLA+AD+ VG LV+PL++L  +    Y
Sbjct: 61  VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAIL--YDY 118

Query: 77  FHTCLMVACPV-----LILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGC 131
                   CPV     ++ + +SI+ L AI++DRY+ ++ P+ +    +  +A + IA  
Sbjct: 119 VWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIV 178

Query: 132 WILSFVVGL-TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVL 190
           W +S  V +  P+ G   L   E+ +  N +            V++    V    FV   
Sbjct: 179 WAISIGVSVPIPVIG---LRDEEKVFVNNTTC-----------VLNDPNFVLIGSFVAFF 224

Query: 191 PPLLLMVLIYLEVFYLIRKQL------------------------NKKVSASSGDP---- 222
            PL +MV+ Y    Y++R+Q                         N     +S +P    
Sbjct: 225 IPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQ 284

Query: 223 ---------------QKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC-PSCHKP 266
                           +    E K +K L ++ F+F + W P  I N +++ C  SC++ 
Sbjct: 285 NARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQK 344

Query: 267 SILTYIAIFLTHGN--SAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPI 315
            +   + +F+  G   S +NP+VY    + +R  F      +++ +  PP+
Sbjct: 345 LMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPV 395


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/296 (27%), Positives = 142/296 (47%), Gaps = 29/296 (9%)

Query: 13  IGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIG 72
           +G+ + + +  +  N+LV+ A+ VN+      +  + +LA AD   G     L  + N G
Sbjct: 53  MGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYL--MFNTG 110

Query: 73  PQTY---FHTCLMVACPVLILTQSSILALLAIAVDRYLRV-KIPLRYKMVVTPRRAAVAI 128
           P T      T L+    +     +S+  LLAIA++R++ V ++ L  +M  + RR  V I
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRM--SNRRVVVVI 168

Query: 129 AGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVW 188
              W ++ V+G  P  GWN +  +E                    + S  Y+V++  F  
Sbjct: 169 VVIWTMAIVMGAIPSVGWNCICDIENC-------------SNMAPLYSDSYLVFWAIFNL 215

Query: 189 VLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWL 248
           V    ++MV++Y  +F  +R Q   ++S  S  P++     + + K++ ++L  F + W 
Sbjct: 216 VT--FVVMVVLYAHIFGYVR-QRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWT 272

Query: 249 PLHILNCITLFCPSCHKPSILTYIAIF--LTHGNSAMNPIVYAFRIQKFRVTFLKI 302
           P  +L  + + CP C    +L Y   F  L   NSAMNPI+Y++R ++   TF +I
Sbjct: 273 PGLVLLLLDVCCPQC---DVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQI 325


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/296 (27%), Positives = 142/296 (47%), Gaps = 29/296 (9%)

Query: 13  IGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIG 72
           +G+ + + +  +  N+LV+ A+ VN+      +  + +LA AD   G     L  + N G
Sbjct: 53  MGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYL--MFNTG 110

Query: 73  PQTY---FHTCLMVACPVLILTQSSILALLAIAVDRYLRV-KIPLRYKMVVTPRRAAVAI 128
           P T      T L+    +     +S+  LLAIA++R++ V ++ L  +M  + RR  V I
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRM--SNRRVVVVI 168

Query: 129 AGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVW 188
              W ++ V+G  P  GWN +  +E                    + S  Y+V++  F  
Sbjct: 169 VVIWTMAIVMGAIPSVGWNCICDIENC-------------SNMAPLYSDSYLVFWAIFNL 215

Query: 189 VLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWL 248
           V    ++MV++Y  +F  +R Q   ++S  S  P++     + + K++ ++L  F + W 
Sbjct: 216 VT--FVVMVVLYAHIFGYVR-QRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWT 272

Query: 249 PLHILNCITLFCPSCHKPSILTYIAIF--LTHGNSAMNPIVYAFRIQKFRVTFLKI 302
           P  +L  + + CP C    +L Y   F  L   NSAMNPI+Y++R ++   TF +I
Sbjct: 273 PGLVLLLLDVCCPQC---DVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQI 325


>gi|4503391 dopamine receptor D5 [Homo sapiens]
          Length = 477

 Score =  104 bits (259), Expect = 1e-22
 Identities = 92/354 (25%), Positives = 157/354 (44%), Gaps = 47/354 (13%)

Query: 3   PSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALR-DATFCFIVSLAVADVAVGAL 61
           P +   Q     +  L+ + ++ GNVLV  A+  ++ LR + T  FIVSLAV+D+ V  L
Sbjct: 34  PPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALL 93

Query: 62  VIPLAILINIGPQTYFHT-CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT 120
           V+P   +  +     F   C +     ++ + +SIL L  I+VDRY  +  P RYK  +T
Sbjct: 94  VMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMT 153

Query: 121 PRRAAVAIAGCWILSFVVGLTPM-FGWNNLSAVERAWAA-------------NGSMGEPV 166
            R A V +   W LS ++   P+   W+   A   +W                    EP 
Sbjct: 154 QRMALVMVGLAWTLSILISFIPVQLNWHRDQAA--SWGGLDLPNNLANWTPWEEDFWEPD 211

Query: 167 IKCE-FEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVS--------- 216
           +  E  +  ++  Y +  +   + + P+ +M++ Y  ++ + + Q+ +  S         
Sbjct: 212 VNAENCDSSLNRTYAISSSLISFYI-PVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQ 270

Query: 217 --------ASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC------PS 262
                   A     +    KE K+ K+L++I+ +F   WLP  ILNC+  FC      P 
Sbjct: 271 SCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPP 330

Query: 263 CHKPSIL-TYIAIFLTHG--NSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAP 313
              P +  T   +F+  G  NS++NP++YAF    F+  F ++      C   P
Sbjct: 331 AGFPCVSETTFDVFVWFGWANSSLNPVIYAFNAD-FQKVFAQLLGCSHFCSRTP 383


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score =  102 bits (255), Expect = 4e-22
 Identities = 93/311 (29%), Positives = 144/311 (46%), Gaps = 39/311 (12%)

Query: 18  LIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLA---ILINIGPQ 74
           LI L  V GNVLVI A+   + L+  T  FI SLA AD+ +G  V+P     IL+ +   
Sbjct: 42  LIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTF 101

Query: 75  TYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWIL 134
             F      +  VL +T +SI  L  IAVDRY  +  P +Y+ ++T  +A V I   WI+
Sbjct: 102 GNFWCEFWTSIDVLCVT-ASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIV 160

Query: 135 SFVVGLTPM-FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
           S +    P+   W   +  E   A N    E    C+F    + +     +  V    PL
Sbjct: 161 SGLTSFLPIQMHWYRATHQE---AINCYANETC--CDF---FTNQAYAIASSIVSFYVPL 212

Query: 194 LLMVLIYLEVFYLIRKQLNKKVSASSG---------------------DPQKYYGKELKI 232
           ++MV +Y  VF   ++QL +K+  S G                        K+  KE K 
Sbjct: 213 VIMVFVYSRVFQEAKRQL-QKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKA 271

Query: 233 AKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAI-FLTHGNSAMNPIVYAFR 291
            K+L +I+  F L WLP  I+N + +   +  +  +  YI + ++ + NS  NP++Y  R
Sbjct: 272 LKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEV--YILLNWIGYVNSGFNPLIYC-R 328

Query: 292 IQKFRVTFLKI 302
              FR+ F ++
Sbjct: 329 SPDFRIAFQEL 339


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score =  102 bits (254), Expect = 5e-22
 Identities = 97/329 (29%), Positives = 148/329 (44%), Gaps = 49/329 (14%)

Query: 10  AAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILI 69
           AAY+ + V    V++ GN LV  AV  N  +R  T  FIV+L++ADV V A+ +P ++L+
Sbjct: 51  AAYVAVFV----VALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106

Query: 70  NIGPQTYFHTCLMVACPVL--ILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVA 127
           +I     F   L    P L  +    ++L L  IA+DR+  +  PL +K   T RRA  +
Sbjct: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKS--TARRARGS 164

Query: 128 IAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFN--F 185
           I G W +S  + + P       S+V    A    +      C+      +   +Y +  F
Sbjct: 165 ILGIWAVSLAI-MVPQAAVMECSSVLPELANRTRL---FSVCDERWADDLYPKIYHSCFF 220

Query: 186 FVWVLPPLLLMVLIYLEVF-------------YLIRK------QLNKKVSASSGDPQ--- 223
            V  L PL LM + Y ++F              L+R       QL       SG+PQ   
Sbjct: 221 IVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRA 280

Query: 224 -------KYYGKELKIAKSLALILFLFALSWLPLHILNCIT----LFCPSCHKPSILTYI 272
                  K      K AK L ++L +FAL +LP+ +LN +     +F  +  + ++    
Sbjct: 281 RAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACF 340

Query: 273 AI--FLTHGNSAMNPIVYAFRIQKFRVTF 299
               +L + NSA NPI+Y F   KFR  F
Sbjct: 341 TFSHWLVYANSAANPIIYNFLSGKFREQF 369


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score =  100 bits (249), Expect = 2e-21
 Identities = 81/309 (26%), Positives = 141/309 (45%), Gaps = 44/309 (14%)

Query: 17  VLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTY 76
           V+IAL +   N L+I  +    ALR+ +  F+VSL  +D+ VG +V+P A+L  +  +  
Sbjct: 35  VVIALTAA-ANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWV 93

Query: 77  FHT--CLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWIL 134
                CL+     ++   +SIL L  I++DRYL +  PLRYK+ +TP RA   + G W L
Sbjct: 94  LARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSL 153

Query: 135 SFVVGLTP-MFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPL 193
           + +    P + GW+ L               P +  +   + S+ +++  +   + LP  
Sbjct: 154 AALASFLPLLLGWHEL-----------GHARPPVPGQCRLLASLPFVLVASGLTFFLPSG 202

Query: 194 LLMVLIYLEVFYLIRKQLNKKVSASSGDPQ--------------------------KYYG 227
            +    Y  +    RKQ  +  S ++G                             K+  
Sbjct: 203 AI-CFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSR 261

Query: 228 KELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIV 287
           K LK + +L ++L +F ++WLP  + N +   C  C  P +   +  +L + NS MNPI+
Sbjct: 262 KALKASLTLGILLGMFFVTWLPFFVANIVQAVC-DCISPGLFD-VLTWLGYCNSTMNPII 319

Query: 288 YAFRIQKFR 296
           Y   ++ F+
Sbjct: 320 YPLFMRDFK 328


>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 89/303 (29%), Positives = 143/303 (47%), Gaps = 44/303 (14%)

Query: 13  IGIEVLIAL--VSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGAL----VIPLA 66
           I +EV + L  +S+  N+LVI A+  N+ L    + F+ SLAVAD+ V        I + 
Sbjct: 38  IAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIY 97

Query: 67  ILIN----IGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPR 122
           +L N    I      H   +    + I   +S+ +LLAIAVDRY+ +   LRY  ++T R
Sbjct: 98  LLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTAR 157

Query: 123 RAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVY 182
           R+   IAG W  +F  G   +F   + S               VI C    +ISM + + 
Sbjct: 158 RSGAIIAGIW--AFCTGCGIVFILYSESTY-------------VILC----LISMFFAML 198

Query: 183 FNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFL 242
           F           L+V +Y+ +F L R  + K+++A  G         ++ A ++ ++L +
Sbjct: 199 F-----------LLVSLYIHMFLLARTHV-KRIAALPGASSARQRTSMQGAVTVTMLLGV 246

Query: 243 FALSWLPLHILNCITLFCPS---CHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTF 299
           F + W P  +   + L CP    C +      + + L   NS M+P++YAFR Q+ R TF
Sbjct: 247 FTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTF 306

Query: 300 LKI 302
            +I
Sbjct: 307 KEI 309


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.142    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,650,330
Number of Sequences: 37866
Number of extensions: 433837
Number of successful extensions: 2979
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 484
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 1458
Number of HSP's gapped (non-prelim): 967
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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