Guide to the Human Genome
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Search of human proteins with 219879828

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219879828 rcRPE protein [Homo sapiens]
         (228 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219879828 rcRPE protein [Homo sapiens]                             466   e-132
gi|40385883 ribulose-5-phosphate-3-epimerase isoform 1 [Homo sap...   448   e-126
gi|24307923 ribulose-5-phosphate-3-epimerase isoform 2 [Homo sap...   300   7e-82
gi|61744483 solute carrier family 3, member 2 isoform f [Homo sa...    32   0.34 
gi|61744481 solute carrier family 3, member 2 isoform e [Homo sa...    32   0.34 
gi|61744479 solute carrier family 3, member 2 isoform d [Homo sa...    32   0.34 
gi|65506891 solute carrier family 3, member 2 isoform c [Homo sa...    32   0.34 
gi|61744477 solute carrier family 3, member 2 isoform b [Homo sa...    32   0.34 
gi|61744475 solute carrier family 3, member 2 isoform a [Homo sa...    32   0.34 
gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2 [...    30   1.3  
gi|4503273 angiotensin I converting enzyme 1 isoform 1 precursor...    28   5.0  
gi|23238214 angiotensin I converting enzyme 1 isoform 2 precurso...    28   5.0  
gi|45269149 quinolinate phosphoribosyltransferase [Homo sapiens]       28   6.5  
gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6 [...    28   6.5  
gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5 [...    28   6.5  
gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4 [...    28   6.5  
gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3 [...    28   6.5  
gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1 [...    28   6.5  
gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]           28   8.5  
gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens]           28   8.5  

>gi|219879828 rcRPE protein [Homo sapiens]
          Length = 228

 Score =  466 bits (1200), Expect = e-132
 Identities = 228/228 (100%), Positives = 228/228 (100%)

Query: 1   MASGCKIGPSILNSDLANLGAKCLQMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 60
           MASGCKIGPSILNSDLANLGAKCLQMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ
Sbjct: 1   MASGCKIGPSILNSDLANLGAKCLQMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 60

Query: 61  LGQDPFFDMHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIK 120
           LGQDPFFDMHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIK
Sbjct: 61  LGQDPFFDMHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIK 120

Query: 121 PGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSLDIEGDGGVGS 180
           PGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSLDIEGDGGVGS
Sbjct: 121 PGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSLDIEGDGGVGS 180

Query: 181 DTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR 228
           DTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR
Sbjct: 181 DTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR 228


>gi|40385883 ribulose-5-phosphate-3-epimerase isoform 1 [Homo
           sapiens]
          Length = 228

 Score =  448 bits (1152), Expect = e-126
 Identities = 219/228 (96%), Positives = 222/228 (97%)

Query: 1   MASGCKIGPSILNSDLANLGAKCLQMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 60
           MASGCKIGPSILNSDLANLGA+CL+MLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ
Sbjct: 1   MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 60

Query: 61  LGQDPFFDMHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIK 120
           LGQDPFFDMHMMVSKPEQWVKPMAVA ANQYTFHLEATENPG LIKDIRENGMKVGLAIK
Sbjct: 61  LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK 120

Query: 121 PGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSLDIEGDGGVGS 180
           PGTSVEYLAPWANQIDMALVMTVEPGFG QKFMEDMMPKVHWLRTQFPSLDIE DGGVG 
Sbjct: 121 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP 180

Query: 181 DTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR 228
           DTVHKCAEAGANM VSGSAIMRSEDPRSVINLLRN+CSEAAQKRSLDR
Sbjct: 181 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR 228


>gi|24307923 ribulose-5-phosphate-3-epimerase isoform 2 [Homo
           sapiens]
          Length = 178

 Score =  300 bits (768), Expect = 7e-82
 Identities = 153/178 (85%), Positives = 154/178 (86%), Gaps = 18/178 (10%)

Query: 69  MHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMK-------------- 114
           MHMMVSKPEQWVKPMAVA ANQYTFHLEATENPG LIKDIRENGMK              
Sbjct: 1   MHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKSCSVTQAEVQWHSQ 60

Query: 115 ----VGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSL 170
               VGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFG QKFMEDMMPKVHWLRTQFPSL
Sbjct: 61  GPLQVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSL 120

Query: 171 DIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR 228
           DIE DGGVG DTVHKCAEAGANM VSGSAIMRSEDPRSVINLLRN+CSEAAQKRSLDR
Sbjct: 121 DIEVDGGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR 178


>gi|61744483 solute carrier family 3, member 2 isoform f [Homo
           sapiens]
          Length = 529

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 158 PKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNIC 217
           P + W  + FP  DI G                ANMTV G    +SEDP S+++L R + 
Sbjct: 386 PVMLWDESSFP--DIPG-------------AVSANMTVKG----QSEDPGSLLSLFRRLS 426

Query: 218 SEAAQKRSL 226
            + +++RSL
Sbjct: 427 DQRSKERSL 435


>gi|61744481 solute carrier family 3, member 2 isoform e [Homo
           sapiens]
          Length = 568

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 158 PKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNIC 217
           P + W  + FP  DI G                ANMTV G    +SEDP S+++L R + 
Sbjct: 425 PVMLWDESSFP--DIPG-------------AVSANMTVKG----QSEDPGSLLSLFRRLS 465

Query: 218 SEAAQKRSL 226
            + +++RSL
Sbjct: 466 DQRSKERSL 474


>gi|61744479 solute carrier family 3, member 2 isoform d [Homo
           sapiens]
          Length = 599

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 158 PKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNIC 217
           P + W  + FP  DI G                ANMTV G    +SEDP S+++L R + 
Sbjct: 456 PVMLWDESSFP--DIPG-------------AVSANMTVKG----QSEDPGSLLSLFRRLS 496

Query: 218 SEAAQKRSL 226
            + +++RSL
Sbjct: 497 DQRSKERSL 505


>gi|65506891 solute carrier family 3, member 2 isoform c [Homo
           sapiens]
          Length = 630

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 158 PKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNIC 217
           P + W  + FP  DI G                ANMTV G    +SEDP S+++L R + 
Sbjct: 487 PVMLWDESSFP--DIPG-------------AVSANMTVKG----QSEDPGSLLSLFRRLS 527

Query: 218 SEAAQKRSL 226
            + +++RSL
Sbjct: 528 DQRSKERSL 536


>gi|61744477 solute carrier family 3, member 2 isoform b [Homo
           sapiens]
          Length = 631

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 158 PKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNIC 217
           P + W  + FP  DI G                ANMTV G    +SEDP S+++L R + 
Sbjct: 488 PVMLWDESSFP--DIPG-------------AVSANMTVKG----QSEDPGSLLSLFRRLS 528

Query: 218 SEAAQKRSL 226
            + +++RSL
Sbjct: 529 DQRSKERSL 537


>gi|61744475 solute carrier family 3, member 2 isoform a [Homo
           sapiens]
          Length = 661

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 158 PKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNIC 217
           P + W  + FP  DI G                ANMTV G    +SEDP S+++L R + 
Sbjct: 518 PVMLWDESSFP--DIPG-------------AVSANMTVKG----QSEDPGSLLSLFRRLS 558

Query: 218 SEAAQKRSL 226
            + +++RSL
Sbjct: 559 DQRSKERSL 567


>gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2
           [Homo sapiens]
          Length = 607

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 8/129 (6%)

Query: 14  SDLANLGAKCLQMLDSGADYLHLDVMDGHFVP-NITFGHPVVESLRKQLGQDPFFDMHMM 72
           ++ A   A C+ M+D+G     +D++D H    N+T  H  + +LR  L         M+
Sbjct: 342 ANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALR-NLAIPVINKAKML 400

Query: 73  VSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIKPGTSVEYLAPWA 132
            +   + V     +E     F L  T     ++ D +E   ++G  +K    VE L  W 
Sbjct: 401 SAGVTEAVLKFLKSEMPPVQFKLLGTLR---MLIDAQEAAEQLGKNVK---LVERLVEWC 454

Query: 133 NQIDMALVM 141
              D A VM
Sbjct: 455 EAKDHAGVM 463


>gi|4503273 angiotensin I converting enzyme 1 isoform 1 precursor
            [Homo sapiens]
          Length = 1306

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 14/84 (16%)

Query: 90   QYTFH---LEATENPGTLIK-DI---RENGMKVGLAIKPGTSVEYLAPWANQIDMALVMT 142
            Q+ FH    +A  + G L K DI   +E G ++  A+K G S     PW   + +   +T
Sbjct: 1135 QFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFS----RPWPEAMQL---IT 1187

Query: 143  VEPGFGEQKFMEDMMPKVHWLRTQ 166
             +P       +    P + WLRT+
Sbjct: 1188 GQPNMSASAMLSYFKPLLDWLRTE 1211


>gi|23238214 angiotensin I converting enzyme 1 isoform 2 precursor
           [Homo sapiens]
          Length = 732

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 14/84 (16%)

Query: 90  QYTFH---LEATENPGTLIK-DI---RENGMKVGLAIKPGTSVEYLAPWANQIDMALVMT 142
           Q+ FH    +A  + G L K DI   +E G ++  A+K G S     PW   + +   +T
Sbjct: 561 QFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFS----RPWPEAMQL---IT 613

Query: 143 VEPGFGEQKFMEDMMPKVHWLRTQ 166
            +P       +    P + WLRT+
Sbjct: 614 GQPNMSASAMLSYFKPLLDWLRTE 637


>gi|45269149 quinolinate phosphoribosyltransferase [Homo sapiens]
          Length = 297

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query: 154 EDMMPKVHWLRTQFPSLDIEGDGGVGSDTV 183
           E++ P    L+ QFPS+ +E  GG+  D +
Sbjct: 227 EELHPTATVLKAQFPSVAVEASGGITLDNL 256


>gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6
           [Homo sapiens]
          Length = 516

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 14  SDLANLGAKCLQMLDSGADYLHLDVMDGHFVP-NITFGHPVVESLR 58
           ++ A   A C+ M+D+G     +D++D H    N+T  H  + +LR
Sbjct: 250 ANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALR 295


>gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5
           [Homo sapiens]
          Length = 558

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 14  SDLANLGAKCLQMLDSGADYLHLDVMDGHFVP-NITFGHPVVESLR 58
           ++ A   A C+ M+D+G     +D++D H    N+T  H  + +LR
Sbjct: 292 ANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALR 337


>gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4
           [Homo sapiens]
          Length = 559

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 14  SDLANLGAKCLQMLDSGADYLHLDVMDGHFVP-NITFGHPVVESLR 58
           ++ A   A C+ M+D+G     +D++D H    N+T  H  + +LR
Sbjct: 293 ANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALR 338


>gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3
           [Homo sapiens]
          Length = 607

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 14  SDLANLGAKCLQMLDSGADYLHLDVMDGHFVP-NITFGHPVVESLR 58
           ++ A   A C+ M+D+G     +D++D H    N+T  H  + +LR
Sbjct: 341 ANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALR 386


>gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1
           [Homo sapiens]
          Length = 608

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 14  SDLANLGAKCLQMLDSGADYLHLDVMDGHFVP-NITFGHPVVESLR 58
           ++ A   A C+ M+D+G     +D++D H    N+T  H  + +LR
Sbjct: 342 ANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALR 387


>gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]
          Length = 1095

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 102 GTLIKDIRENGMK------VGLAIKPGTSVEYLAPWANQIDMALVMT------VEPGFGE 149
           G   +  R NG+          +I  G + E L   AN  D+A +        V      
Sbjct: 169 GKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQP 228

Query: 150 QKFMEDMM--PKVHWLRTQFPSLDIEGDGGVGSDT 182
             FME     P+  WL+T F + D++G+G +  DT
Sbjct: 229 LDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDT 263


>gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens]
          Length = 997

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 102 GTLIKDIRENGMK------VGLAIKPGTSVEYLAPWANQIDMALVMT------VEPGFGE 149
           G   +  R NG+          +I  G + E L   AN  D+A +        V      
Sbjct: 71  GKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQP 130

Query: 150 QKFMEDMM--PKVHWLRTQFPSLDIEGDGGVGSDT 182
             FME     P+  WL+T F + D++G+G +  DT
Sbjct: 131 LDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDT 165


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,713,326
Number of Sequences: 37866
Number of extensions: 370104
Number of successful extensions: 766
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 761
Number of HSP's gapped (non-prelim): 20
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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