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Search of human proteins with 218777840
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218777840 abhydrolase domain containing 9 [Homo sapiens]
(360 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218777840 abhydrolase domain containing 9 [Homo sapiens] 749 0.0
gi|13376164 abhydrolase domain containing 9 [Homo sapiens] 749 0.0
gi|218777837 abhydrolase domain containing 7 [Homo sapiens] 327 1e-89
gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens] 134 1e-31
gi|145611434 abhydrolase domain containing 8 [Homo sapiens] 56 4e-08
gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo sap... 55 7e-08
gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo sap... 55 7e-08
gi|31542303 abhydrolase domain containing 5 [Homo sapiens] 53 5e-07
gi|189027141 abhydrolase domain containing 6 [Homo sapiens] 52 8e-07
gi|29294639 mesoderm specific transcript isoform a [Homo sapiens] 48 2e-05
gi|29294637 mesoderm specific transcript isoform b [Homo sapiens] 48 2e-05
gi|29294635 mesoderm specific transcript isoform b [Homo sapiens] 48 2e-05
gi|18777795 serine hydrolase-like 2 [Homo sapiens] 47 2e-05
gi|221316588 biphenyl hydrolase-like [Homo sapiens] 46 6e-05
gi|50658087 abhydrolase domain containing 4 [Homo sapiens] 40 0.003
gi|7706645 protein phosphatase methylesterase 1 [Homo sapiens] 40 0.004
gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo sa... 37 0.036
gi|4503583 epoxide hydrolase 1 [Homo sapiens] 36 0.061
gi|209862837 epoxide hydrolase 1 [Homo sapiens] 36 0.061
gi|32528310 abhydrolase domain containing 12B isoform c [Homo sa... 35 0.080
gi|32451492 abhydrolase domain containing 12B isoform b [Homo sa... 35 0.080
gi|187937176 NACHT, leucine rich repeat and PYD containing 7 iso... 30 4.4
gi|75709196 NACHT, leucine rich repeat and PYD containing 7 isof... 30 4.4
gi|46049100 NACHT, leucine rich repeat and PYD containing 7 isof... 30 4.4
gi|30410041 late cornified envelope 3B [Homo sapiens] 29 5.7
gi|32481209 mitogen-activated protein kinase-activated protein k... 29 5.7
gi|10863901 mitogen-activated protein kinase-activated protein k... 29 5.7
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 29 7.5
gi|226437571 abhydrolase domain containing 14A [Homo sapiens] 29 7.5
>gi|218777840 abhydrolase domain containing 9 [Homo sapiens]
Length = 360
Score = 749 bits (1934), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRR 60
MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRR
Sbjct: 1 MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRR 60
Query: 61 SASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF 120
SASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF
Sbjct: 61 SASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF 120
Query: 121 QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAW 180
QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAW
Sbjct: 121 QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAW 180
Query: 181 HFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQ 240
HFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQ
Sbjct: 181 HFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQ 240
Query: 241 ILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTL 300
ILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTL
Sbjct: 241 ILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTL 300
Query: 301 LLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD 360
LLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD
Sbjct: 301 LLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD 360
>gi|13376164 abhydrolase domain containing 9 [Homo sapiens]
Length = 360
Score = 749 bits (1934), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRR 60
MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRR
Sbjct: 1 MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRR 60
Query: 61 SASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF 120
SASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF
Sbjct: 61 SASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF 120
Query: 121 QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAW 180
QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAW
Sbjct: 121 QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAW 180
Query: 181 HFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQ 240
HFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQ
Sbjct: 181 HFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQ 240
Query: 241 ILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTL 300
ILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTL
Sbjct: 241 ILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTL 300
Query: 301 LLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD 360
LLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD
Sbjct: 301 LLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD 360
>gi|218777837 abhydrolase domain containing 7 [Homo sapiens]
Length = 362
Score = 327 bits (837), Expect = 1e-89
Identities = 158/348 (45%), Positives = 223/348 (64%), Gaps = 5/348 (1%)
Query: 14 RLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRRSASPACLSDPSLG 73
RL L L WSLV+ + A+++ L + P + R PACLSDPSLG
Sbjct: 10 RLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLG 69
Query: 74 EHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRG 133
H ++ +K SGLR HYV+AG PLML LHGFPE W+SWRYQLREF+S + VVA+DLRG
Sbjct: 70 THCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRG 129
Query: 134 YGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERM 193
YG +DAP Y +D L+ DIKD++ LGYSKC+L+ HDWG ++AW +I YP +V ++
Sbjct: 130 YGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKL 189
Query: 194 VVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTTLTHRKTGI 253
+V++ +V+ +Y L H +Q +S Y + FQ+PW PE + S++DF++LK T TGI
Sbjct: 190 IVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGI 249
Query: 254 ---PC-LTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTY 309
C LT +LEA++Y FSQPG L+GP+N+YRN+F PL+ +TTPTLLLWGE D +
Sbjct: 250 GRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAF 309
Query: 310 LELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQD 357
+E+ + E + +V IL HW+ Q P +++ +W FL++
Sbjct: 310 MEVEMAE-VTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKE 356
>gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 134 bits (338), Expect = 1e-31
Identities = 91/316 (28%), Positives = 155/316 (49%), Gaps = 35/316 (11%)
Query: 69 DPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF-QSRFHVV 127
+PS HG++ +K +RLH+V G +GP + HGFPE+W+SWRYQ+ Q+ + V+
Sbjct: 233 NPSDMSHGYVTVKPR-VRLHFVELG--SGPAVCLCHGFPESWYSWRYQIPALAQAGYRVL 289
Query: 128 AVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYP 187
A+D++GYG S AP +++ Y +++L ++ + LG S+ + + HDWG +L W+ +++YP
Sbjct: 290 AMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYP 349
Query: 188 SLVERMVVVSGAPMSVYQDYS-LHHISQFFRSHYMFLFQLPWLPE------------KLL 234
V + ++ + + S L I Y FQ P + E L
Sbjct: 350 ERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLF 409
Query: 235 SMSDFQILKTTLTHRKTGI-------PCL----TPSELEAFLYNFSQPGGLTGPLNYYRN 283
SD +L G+ P L T E++ ++ F + G GPLN+YRN
Sbjct: 410 RASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKK-SGFRGPLNWYRN 468
Query: 284 LFRNFPLE----PQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWI 339
+ RN+ +++ P L++ EKD L + + + ++P HI GHW
Sbjct: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHM-EDWIPHLKRGHI-EDCGHWT 526
Query: 340 PQSNPQEMHQYMWAFL 355
P E++Q + +L
Sbjct: 527 QMDKPTEVNQILIKWL 542
>gi|145611434 abhydrolase domain containing 8 [Homo sapiens]
Length = 439
Score = 56.2 bits (134), Expect = 4e-08
Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 99 LMLFLHGFPENWFSWRYQLREF-QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKD 157
++ F+HG + W+ QL F + + VVA DL G+G S AP+ YT L D++
Sbjct: 177 VLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRA 236
Query: 158 VILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSG 198
+ + +L+ H +G + YP LV ++++++G
Sbjct: 237 IFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMING 277
>gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo
sapiens]
Length = 315
Score = 55.5 bits (132), Expect = 7e-08
Identities = 59/262 (22%), Positives = 110/262 (41%), Gaps = 18/262 (6%)
Query: 98 PLMLFLHGF--PENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDI 155
P ++FLHG + F+ ++ Q+ V+ VD R +G D+P D + +++ D+
Sbjct: 67 PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSPHSPDM-SYEIMSQDL 123
Query: 156 KDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQF 215
+D++ LG C++V H G A ++ P LVER++ V +P+ + + H + +
Sbjct: 124 QDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPV---ESTGVSHFATY 180
Query: 216 FRSHYMFLF--QLPWLPEKLLSMSDFQILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGG 273
+ +LP + L+ + + R+ + L + F++ +
Sbjct: 181 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVD-GRFVWRVN---- 235
Query: 274 LTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILP 333
L + + FP + PTL L G ++ I R P R + +P
Sbjct: 236 -LDALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEI-MRLFP-RAQMQTVP 292
Query: 334 GIGHWIPQSNPQEMHQYMWAFL 355
GHWI PQ+ + FL
Sbjct: 293 NAGHWIHADRPQDFIAAIRGFL 314
>gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo
sapiens]
Length = 308
Score = 55.5 bits (132), Expect = 7e-08
Identities = 59/262 (22%), Positives = 110/262 (41%), Gaps = 18/262 (6%)
Query: 98 PLMLFLHGF--PENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDI 155
P ++FLHG + F+ ++ Q+ V+ VD R +G D+P D + +++ D+
Sbjct: 60 PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSPHSPDM-SYEIMSQDL 116
Query: 156 KDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQF 215
+D++ LG C++V H G A ++ P LVER++ V +P+ + + H + +
Sbjct: 117 QDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPV---ESTGVSHFATY 173
Query: 216 FRSHYMFLF--QLPWLPEKLLSMSDFQILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGG 273
+ +LP + L+ + + R+ + L + F++ +
Sbjct: 174 VAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVD-GRFVWRVN---- 228
Query: 274 LTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILP 333
L + + FP + PTL L G ++ I R P R + +P
Sbjct: 229 -LDALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEI-MRLFP-RAQMQTVP 285
Query: 334 GIGHWIPQSNPQEMHQYMWAFL 355
GHWI PQ+ + FL
Sbjct: 286 NAGHWIHADRPQDFIAAIRGFL 307
>gi|31542303 abhydrolase domain containing 5 [Homo sapiens]
Length = 349
Score = 52.8 bits (125), Expect = 5e-07
Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
Query: 98 PLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPR-DVDCYTIDLLLVD-I 155
PL+L LHGF W + + V A DL G+G S PR D D ++ V+ I
Sbjct: 77 PLVL-LHGFGGGLGLWALNFGDLCTNRPVYAFDLLGFGRSSRPRFDSDAEEVENQFVESI 135
Query: 156 KDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVV 196
++ LG K IL+ H+ G LA +S+ YPS V +++V
Sbjct: 136 EEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILV 176
>gi|189027141 abhydrolase domain containing 6 [Homo sapiens]
Length = 337
Score = 52.0 bits (123), Expect = 8e-07
Identities = 62/280 (22%), Positives = 113/280 (40%), Gaps = 30/280 (10%)
Query: 89 YVSAGR-GNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYT 147
Y GR G+ P +L LHGF + W ++ H+V VD+ G+ +D +
Sbjct: 62 YSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGH-EGTTRSSLDDLS 120
Query: 148 IDLLLVDIKDVI--LGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQ 205
ID + I + L L LV G +A ++ YYPS V + +V A +
Sbjct: 121 IDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYST 180
Query: 206 DYS-LHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTTLTHRKTGIPCLTPSELEAF 264
D + + + S + ++P +P MS+ L + + + P ++
Sbjct: 181 DNQFVQRLKELQGS--AAVEKIPLIPSTPEEMSEMLQLCSYVRFK-------VPQQILQG 231
Query: 265 LYNFSQPGGLTGPLNYYRNLFRNFPLEP---------QELTTPTLLLWGEKDTYLELGLV 315
L + P N+YR LF E ++ PT ++WG++D L++
Sbjct: 232 LVDVRIPHN-----NFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGA 286
Query: 316 EAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFL 355
+ + ++E +L GH + P++ + + FL
Sbjct: 287 DMLAKSIANCQVE--LLENCGHSVVMERPRKTAKLIIDFL 324
>gi|29294639 mesoderm specific transcript isoform a [Homo sapiens]
Length = 335
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Query: 63 SPACLSDPSLGEHGFLNLKSSGLRLHYVSAGR--GNGPLMLFLHGFPENWFSWRYQLREF 120
SPA S S G+ F K GLR+ Y + G+ +++ LHGFP + + W
Sbjct: 37 SPALHSWKSSGK--FFTYK--GLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDWYKIWEGL 92
Query: 121 QSRFH-VVAVDLRGYGPSDAPRDVDCYTI--DLLLVDIKDVILGLGYSKCILVAHDWGAL 177
RFH V+A+D G+G SD PR Y+I +V+ LGL + L++HD+G +
Sbjct: 93 TLRFHRVIALDFLGFGFSDKPRP-HHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDI 151
Query: 178 LA 179
+A
Sbjct: 152 VA 153
>gi|29294637 mesoderm specific transcript isoform b [Homo sapiens]
Length = 326
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Query: 63 SPACLSDPSLGEHGFLNLKSSGLRLHYVSAGR--GNGPLMLFLHGFPENWFSWRYQLREF 120
SPA S S G+ F K GLR+ Y + G+ +++ LHGFP + + W
Sbjct: 28 SPALHSWKSSGK--FFTYK--GLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDWYKIWEGL 83
Query: 121 QSRFH-VVAVDLRGYGPSDAPRDVDCYTI--DLLLVDIKDVILGLGYSKCILVAHDWGAL 177
RFH V+A+D G+G SD PR Y+I +V+ LGL + L++HD+G +
Sbjct: 84 TLRFHRVIALDFLGFGFSDKPRP-HHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDI 142
Query: 178 LA 179
+A
Sbjct: 143 VA 144
>gi|29294635 mesoderm specific transcript isoform b [Homo sapiens]
Length = 326
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Query: 63 SPACLSDPSLGEHGFLNLKSSGLRLHYVSAGR--GNGPLMLFLHGFPENWFSWRYQLREF 120
SPA S S G+ F K GLR+ Y + G+ +++ LHGFP + + W
Sbjct: 28 SPALHSWKSSGK--FFTYK--GLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDWYKIWEGL 83
Query: 121 QSRFH-VVAVDLRGYGPSDAPRDVDCYTI--DLLLVDIKDVILGLGYSKCILVAHDWGAL 177
RFH V+A+D G+G SD PR Y+I +V+ LGL + L++HD+G +
Sbjct: 84 TLRFHRVIALDFLGFGFSDKPRP-HHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDI 142
Query: 178 LA 179
+A
Sbjct: 143 VA 144
>gi|18777795 serine hydrolase-like 2 [Homo sapiens]
Length = 314
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/154 (21%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Query: 93 GRGNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLL 152
G GP +L LHG+ +N S+ + F+ VA+D G+G S Y + +
Sbjct: 28 GSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTFV 87
Query: 153 VDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHI 212
+I+ V+ L +++ ++ H +G ++ F +P +V++++++ P+ + + + ++
Sbjct: 88 SEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLD-TPLFLLESDEMENL 146
Query: 213 SQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTTL 246
+ R + Q+ E S Q+L+ L
Sbjct: 147 LTYKRRAIEHVLQVEASQEPSHVFSLKQLLQRLL 180
>gi|221316588 biphenyl hydrolase-like [Homo sapiens]
Length = 291
Score = 45.8 bits (107), Expect = 6e-05
Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Query: 83 SGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSR-FHVVAVDLRGYGPSDAP- 140
+G++LHY G G+ ++L + QL+ + F VVA D RGYG S P
Sbjct: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106
Query: 141 RDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVV 195
RD + D D++ L + K L+ G + A + YPS + +MV+
Sbjct: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161
>gi|50658087 abhydrolase domain containing 4 [Homo sapiens]
Length = 342
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Query: 90 VSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAP---RDVDCY 146
VS + + ++ +HGF W + +R + DL G+G S P RD +
Sbjct: 61 VSPEQNDRTPLVMVHGFGGGVGLWILNMDSLSARRTLHTFDLLGFGRSSRPAFPRDPEGA 120
Query: 147 TIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVV 196
D + I+ +G IL+ H G LA +SI YP V+ +++V
Sbjct: 121 E-DEFVTSIETWRETMGIPSMILLGHSLGGFLATSYSIKYPDRVKHLILV 169
>gi|7706645 protein phosphatase methylesterase 1 [Homo sapiens]
Length = 386
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/169 (26%), Positives = 68/169 (40%), Gaps = 13/169 (7%)
Query: 57 GRRRSASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQ 116
GR+R SP S +G V GP++L LHG + SW
Sbjct: 36 GRKRDFSPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVF 95
Query: 117 LREFQSRF--HVVAVDLRGYGPSDA--PRDVDCYTIDLLLVDIKDVILGLGYSKCILVAH 172
SR +VA+DLR +G + P D+ T+ + ++ + + G +L+ H
Sbjct: 96 TAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGH 155
Query: 173 DWGALLAWH--FSIYYPSLVERMV--VVSGAPMSVYQDYSLHHISQFFR 217
G +A H S PSL+ + VV G M +L+ + F R
Sbjct: 156 SMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMD-----ALNSMQNFLR 199
>gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo
sapiens]
Length = 258
Score = 36.6 bits (83), Expect = 0.036
Identities = 24/84 (28%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Query: 98 PLMLFLHGF--PENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDI 155
P ++FLHG + F+ ++ Q+ V+ VD R +G D+P D + +++ D+
Sbjct: 67 PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHG--DSPHSPDM-SYEIMSQDL 123
Query: 156 KDVILGLGYSKCILVAHDWGALLA 179
+D++ LG C++V H G A
Sbjct: 124 QDLLPQLGLVPCVVVGHSMGGKTA 147
Score = 29.6 bits (65), Expect = 4.4
Identities = 20/68 (29%), Positives = 27/68 (39%), Gaps = 2/68 (2%)
Query: 288 FPLEPQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEM 347
FP + PTL L G ++ I R P R + +P GHWI PQ+
Sbjct: 192 FPQRQESYLGPTLFLLGGNSQFVHPSHHPEI-MRLFP-RAQMQTVPNAGHWIHADRPQDF 249
Query: 348 HQYMWAFL 355
+ FL
Sbjct: 250 IAAIRGFL 257
>gi|4503583 epoxide hydrolase 1 [Homo sapiens]
Length = 455
Score = 35.8 bits (81), Expect = 0.061
Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 21/138 (15%)
Query: 72 LGEHGFLNLKSSGLRLHYVS-------AGRGNGPLMLFLHGFPENWFSWRYQLREF---- 120
L + K GL +H++ AG PL++ +HG+P +++ + Y++
Sbjct: 110 LNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLM-VHGWPGSFYEF-YKIIPLLTDP 167
Query: 121 -------QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHD 173
+ F V+ + GYG S+A ++ + K ++L LG+ + + D
Sbjct: 168 KNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYK-LMLRLGFQEFYIQGGD 226
Query: 174 WGALLAWHFSIYYPSLVE 191
WG+L+ + + PS V+
Sbjct: 227 WGSLICTNMAQLVPSHVK 244
>gi|209862837 epoxide hydrolase 1 [Homo sapiens]
Length = 455
Score = 35.8 bits (81), Expect = 0.061
Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 21/138 (15%)
Query: 72 LGEHGFLNLKSSGLRLHYVS-------AGRGNGPLMLFLHGFPENWFSWRYQLREF---- 120
L + K GL +H++ AG PL++ +HG+P +++ + Y++
Sbjct: 110 LNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLM-VHGWPGSFYEF-YKIIPLLTDP 167
Query: 121 -------QSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHD 173
+ F V+ + GYG S+A ++ + K ++L LG+ + + D
Sbjct: 168 KNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYK-LMLRLGFQEFYIQGGD 226
Query: 174 WGALLAWHFSIYYPSLVE 191
WG+L+ + + PS V+
Sbjct: 227 WGSLICTNMAQLVPSHVK 244
>gi|32528310 abhydrolase domain containing 12B isoform c [Homo
sapiens]
Length = 285
Score = 35.4 bits (80), Expect = 0.080
Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 89 YVSAGRGNGPLMLFLHGFPENWF-SWRYQLREFQSR--FHVVAVDLRGYGPSDAPRDVDC 145
Y +A R P++++LHG E+ S R +L + S FHV++VD RG+G S +
Sbjct: 54 YEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLSDGGFHVLSVDYRGFGDSTGKPTEEG 113
Query: 146 YTIDLLLV 153
T D + V
Sbjct: 114 LTTDAICV 121
>gi|32451492 abhydrolase domain containing 12B isoform b [Homo
sapiens]
Length = 255
Score = 35.4 bits (80), Expect = 0.080
Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 89 YVSAGRGNGPLMLFLHGFPENWF-SWRYQLREFQSR--FHVVAVDLRGYGPSDAPRDVDC 145
Y +A R P++++LHG E+ S R +L + S FHV++VD RG+G S +
Sbjct: 24 YEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLSDGGFHVLSVDYRGFGDSTGKPTEEG 83
Query: 146 YTIDLLLV 153
T D + V
Sbjct: 84 LTTDAICV 91
>gi|187937176 NACHT, leucine rich repeat and PYD containing 7
isoform 3 [Homo sapiens]
Length = 1037
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 190 VERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSD-FQILKTTLTH 248
++++ + + P + Y+D+ L I + +H + W +L + D + K L +
Sbjct: 706 LQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQY 765
Query: 249 RKTGIPCLTPSELEAFLY 266
+ G C TP + F Y
Sbjct: 766 LRLGGHCATPEQWAEFFY 783
>gi|75709196 NACHT, leucine rich repeat and PYD containing 7 isoform
2 [Homo sapiens]
Length = 980
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 190 VERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSD-FQILKTTLTH 248
++++ + + P + Y+D+ L I + +H + W +L + D + K L +
Sbjct: 706 LQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQY 765
Query: 249 RKTGIPCLTPSELEAFLY 266
+ G C TP + F Y
Sbjct: 766 LRLGGHCATPEQWAEFFY 783
>gi|46049100 NACHT, leucine rich repeat and PYD containing 7 isoform
1 [Homo sapiens]
Length = 1009
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 190 VERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSD-FQILKTTLTH 248
++++ + + P + Y+D+ L I + +H + W +L + D + K L +
Sbjct: 678 LQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQY 737
Query: 249 RKTGIPCLTPSELEAFLY 266
+ G C TP + F Y
Sbjct: 738 LRLGGHCATPEQWAEFFY 755
>gi|30410041 late cornified envelope 3B [Homo sapiens]
Length = 95
Score = 29.3 bits (64), Expect = 5.7
Identities = 12/28 (42%), Positives = 13/28 (46%)
Query: 41 CIALTHVLCRPRRGCCGRRRSASPACLS 68
C+ C PR GCCG S CLS
Sbjct: 29 CLPPASSCCAPRPGCCGGPSSEGGCCLS 56
>gi|32481209 mitogen-activated protein kinase-activated protein
kinase 2 isoform 2 [Homo sapiens]
Length = 400
Score = 29.3 bits (64), Expect = 5.7
Identities = 11/29 (37%), Positives = 15/29 (51%)
Query: 230 PEKLLSMSDFQILKTTLTHRKTGIPCLTP 258
P +L ++DF K T +H PC TP
Sbjct: 199 PNAILKLTDFGFAKETTSHNSLTTPCYTP 227
>gi|10863901 mitogen-activated protein kinase-activated protein
kinase 2 isoform 1 [Homo sapiens]
Length = 370
Score = 29.3 bits (64), Expect = 5.7
Identities = 11/29 (37%), Positives = 15/29 (51%)
Query: 230 PEKLLSMSDFQILKTTLTHRKTGIPCLTP 258
P +L ++DF K T +H PC TP
Sbjct: 199 PNAILKLTDFGFAKETTSHNSLTTPCYTP 227
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 28.9 bits (63), Expect = 7.5
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 183 SIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQIL 242
S+ SL+ ++V++ + Q H +S H++ + ++ S Q L
Sbjct: 1564 SVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSL 1623
Query: 243 KTTLTHRKTGIPCLTPSEL------EAFLYNFSQPGGLTGPL 278
KT + P L+P+ +FLYN+ G GPL
Sbjct: 1624 KTIASSE----PSLSPAACWIDVLGRSFLYNYEYLGPRLGPL 1661
>gi|226437571 abhydrolase domain containing 14A [Homo sapiens]
Length = 271
Score = 28.9 bits (63), Expect = 7.5
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 297 TPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQ 356
TPTL+L+GE D L + + R +P L GH PQ+ H + AFL
Sbjct: 212 TPTLILYGELDHILARESLRQL--RHLPNHSVVK-LRNAGHACYLHKPQDFHLVLLAFLD 268
Query: 357 DL 358
L
Sbjct: 269 HL 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.142 0.463
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,139,577
Number of Sequences: 37866
Number of extensions: 714785
Number of successful extensions: 1686
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1651
Number of HSP's gapped (non-prelim): 36
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.