Guide to the Human Genome
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Search of human proteins with 216547715

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|216547715 basic helix-loop-helix domain containing, class B,
9 [Homo sapiens]
         (547 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|216547715 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|216547682 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|216547672 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|216547663 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|216547655 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|216547646 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|216547639 basic helix-loop-helix domain containing, class B, ...  1100   0.0  
gi|39930463 basic helix-loop-helix domain containing, class B, 9...  1100   0.0  
gi|150378528 G protein-coupled receptor associated sorting prote...   236   5e-62
gi|150378489 G protein-coupled receptor associated sorting prote...   236   5e-62
gi|103472136 G protein-coupled receptor associated sorting prote...   236   5e-62
gi|51702248 G protein-coupled receptor associated sorting protei...   231   2e-60
gi|19923967 G protein-coupled receptor associated sorting protei...   231   2e-60
gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens]    213   5e-55
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...   181   2e-45
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]    122   8e-28
gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]    122   8e-28
gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]     122   8e-28
gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens]     119   9e-27
gi|238776793 SVH protein isoform b [Homo sapiens]                     112   7e-25
gi|31377663 SVH protein isoform a [Homo sapiens]                      112   7e-25
gi|7662162 ALEX2 protein [Homo sapiens]                                95   2e-19
gi|29540562 ALEX2 protein [Homo sapiens]                               95   2e-19
gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo s...    84   3e-16
gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo s...    84   4e-16
gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo s...    84   4e-16
gi|238776797 SVH protein isoform e [Homo sapiens]                      83   6e-16
gi|169217162 PREDICTED: similar to armadillo repeat containing, ...    60   4e-09
gi|169216354 PREDICTED: similar to armadillo repeat containing, ...    60   4e-09
gi|169216627 PREDICTED: similar to armadillo repeat containing, ...    60   4e-09

>gi|216547715 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|216547682 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|216547672 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|216547663 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|216547655 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|216547646 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|216547639 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|39930463 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score = 1100 bits (2845), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120
           VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
Sbjct: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN 120

Query: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180
           SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
Sbjct: 121 SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE 180

Query: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
           GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240

Query: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300
           ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR 300

Query: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360
           IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
Sbjct: 301 IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF 360

Query: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420
           INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
Sbjct: 361 INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP 420

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
           GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
Sbjct: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540
           MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
Sbjct: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV 540

Query: 541 KEIIETM 547
           KEIIETM
Sbjct: 541 KEIIETM 547


>gi|150378528 G protein-coupled receptor associated sorting protein 1
            [Homo sapiens]
          Length = 1395

 Score =  236 bits (601), Expect = 5e-62
 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%)

Query: 2    AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56
            A T+ + R  A  EK+  + +  GA  E    +R  A + +K+  K   +   +      
Sbjct: 795  AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849

Query: 57   -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109
             E    +   V  E+K G   E  T+G       + + +AG+   E   S  + E    +
Sbjct: 850  EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909

Query: 110  WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142
            WFW G                  EE  + SWFW+ ++A     + +T   KPE      +
Sbjct: 910  WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969

Query: 143  GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199
            G+   AE+        G++C  R+ A+E+E   ++G+WFW GD+  F+ NP PV R +  
Sbjct: 970  GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027

Query: 200  QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252
                   E +   RP+ W EVT+     P      P++  FR   P EA+     +    
Sbjct: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085

Query: 253  EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312
              N    P         +     QP PE  F  DP  +++ EIR  +R +E    +  +C
Sbjct: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142

Query: 313  PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371
             C + E  + SEEFE+L+ L++   DP IH+I++IAMG+ +   F ++FI + GVV+LIE
Sbjct: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202

Query: 372  SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428
            +LL++PS  +R    + +I + PP  +     I+ ++  +C+ET+++ ++SP Q SG+++
Sbjct: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260

Query: 429  LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488
            +  LTT   +H +VANY S    LL++GN KTR  VLK+LLN+SEN    +++++ +A++
Sbjct: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320

Query: 489  ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547
                +FN++E   N+   +AIF NI  +I+K ++   D  +   L++ F +V++  + +
Sbjct: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%)

Query: 5   KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63
           K + RA+A T+++A  +A+A A++EA      +  T   A  ++    +A  E    V  
Sbjct: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431

Query: 64  NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112
             ++             T   + S P+T G+ +GD    A  E TS     EA +++   
Sbjct: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490

Query: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171
           A +E  I  SWFW GEE       +         + A  +E   G  C+ R+ +EEEE  
Sbjct: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548

Query: 172 NVIGNWFWEGDDTSFD 187
            VIG WFW G+    +
Sbjct: 549 -VIGPWFWSGEQVDIE 563



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49
           AG +   RA+ + +++A I    G+            E  A    RP+ K  A+A+A T 
Sbjct: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381

Query: 50  SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109
                    K  +K K  A  K+ A SE + L   +G +   A +ES+ +   +EA  ++
Sbjct: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425

Query: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161
                +E+ I SWFW  EEA  G   S+K+    D   IG  +    E+     GA+   
Sbjct: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485

Query: 162 RSGAEEEEEENVIGNWFWEGDDTS 185
            S    ++E+ +IG+WFW G++ +
Sbjct: 486 ESILAADDEQVIIGSWFWAGEEVN 509



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MA  +  T ++++T ++  I + +G+E E+  V  P    R K    +G + D  +  + 
Sbjct: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285

Query: 61  VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111
            SK +V  E+  G+  E         GK A      +AG E+ +      K EA  D   
Sbjct: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345

Query: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168
            + +     S FW  EE  N+FS    K E  A+    EE +  A A  K  + +EEE  
Sbjct: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404

Query: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195
                                    E+E++IG+WFW  ++ S        SR
Sbjct: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%)

Query: 90  PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140
           P  G    S   + E   ++WFW+ +    EA I SW W  EE+     G       ++ 
Sbjct: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746

Query: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188
            I      +E E  + A  +  S  E EE + +IG+WFW G++   +P
Sbjct: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47
           A  KNK++       K    A  GA  ++     PV++ + +A              K +
Sbjct: 50  ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109

Query: 48  TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97
             S+T+ +A      +   V+K K ++E +E       S P+        F P   ++  
Sbjct: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169

Query: 98  SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147
           ++         T K EA  ++ F W   + +++S FW+G+E    F   N   +    + 
Sbjct: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227

Query: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192
               E    A+   RS   +E         E+E+V   WFW  D T+       DPN + 
Sbjct: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282

Query: 193 VSRIVKPQPVY 203
            SR    + VY
Sbjct: 283 -SRFRSKKEVY 292



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%)

Query: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156
           C   AG  +W    EE    +NSWFW         S K  KPE  IG+ + A E     G
Sbjct: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734

Query: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195
              K +   EEE    +I +WFW+ D+   +   +  SR
Sbjct: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%)

Query: 97  TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148
           T   C+ E   D    A EE  I  SWFW   EA      NS S+  DK E  I      
Sbjct: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649

Query: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179
           EE  ++   G  C+  +GAEE                           EEEE+++ +WFW
Sbjct: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54
           M G + ++ AQ K EKK   +   GA  E +   VVRP  +T+A+    A+ K  SK   
Sbjct: 1   MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60

Query: 55  VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104
            A  K  +     A  K  A + P +  K        P+ G E  S T +N         
Sbjct: 61  GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120

Query: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158
              TD+   A        +     E  N    SF  +    + G Q      E    G+ 
Sbjct: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175

Query: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190
           C PR  +++E   N    W        FW GD+ +   +P
Sbjct: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215


>gi|150378489 G protein-coupled receptor associated sorting protein 1
            [Homo sapiens]
          Length = 1395

 Score =  236 bits (601), Expect = 5e-62
 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%)

Query: 2    AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56
            A T+ + R  A  EK+  + +  GA  E    +R  A + +K+  K   +   +      
Sbjct: 795  AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849

Query: 57   -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109
             E    +   V  E+K G   E  T+G       + + +AG+   E   S  + E    +
Sbjct: 850  EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909

Query: 110  WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142
            WFW G                  EE  + SWFW+ ++A     + +T   KPE      +
Sbjct: 910  WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969

Query: 143  GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199
            G+   AE+        G++C  R+ A+E+E   ++G+WFW GD+  F+ NP PV R +  
Sbjct: 970  GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027

Query: 200  QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252
                   E +   RP+ W EVT+     P      P++  FR   P EA+     +    
Sbjct: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085

Query: 253  EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312
              N    P         +     QP PE  F  DP  +++ EIR  +R +E    +  +C
Sbjct: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142

Query: 313  PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371
             C + E  + SEEFE+L+ L++   DP IH+I++IAMG+ +   F ++FI + GVV+LIE
Sbjct: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202

Query: 372  SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428
            +LL++PS  +R    + +I + PP  +     I+ ++  +C+ET+++ ++SP Q SG+++
Sbjct: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260

Query: 429  LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488
            +  LTT   +H +VANY S    LL++GN KTR  VLK+LLN+SEN    +++++ +A++
Sbjct: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320

Query: 489  ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547
                +FN++E   N+   +AIF NI  +I+K ++   D  +   L++ F +V++  + +
Sbjct: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%)

Query: 5   KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63
           K + RA+A T+++A  +A+A A++EA      +  T   A  ++    +A  E    V  
Sbjct: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431

Query: 64  NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112
             ++             T   + S P+T G+ +GD    A  E TS     EA +++   
Sbjct: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490

Query: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171
           A +E  I  SWFW GEE       +         + A  +E   G  C+ R+ +EEEE  
Sbjct: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548

Query: 172 NVIGNWFWEGDDTSFD 187
            VIG WFW G+    +
Sbjct: 549 -VIGPWFWSGEQVDIE 563



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49
           AG +   RA+ + +++A I    G+            E  A    RP+ K  A+A+A T 
Sbjct: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381

Query: 50  SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109
                    K  +K K  A  K+ A SE + L   +G +   A +ES+ +   +EA  ++
Sbjct: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425

Query: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161
                +E+ I SWFW  EEA  G   S+K+    D   IG  +    E+     GA+   
Sbjct: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485

Query: 162 RSGAEEEEEENVIGNWFWEGDDTS 185
            S    ++E+ +IG+WFW G++ +
Sbjct: 486 ESILAADDEQVIIGSWFWAGEEVN 509



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MA  +  T ++++T ++  I + +G+E E+  V  P    R K    +G + D  +  + 
Sbjct: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285

Query: 61  VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111
            SK +V  E+  G+  E         GK A      +AG E+ +      K EA  D   
Sbjct: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345

Query: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168
            + +     S FW  EE  N+FS    K E  A+    EE +  A A  K  + +EEE  
Sbjct: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404

Query: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195
                                    E+E++IG+WFW  ++ S        SR
Sbjct: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%)

Query: 90  PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140
           P  G    S   + E   ++WFW+ +    EA I SW W  EE+     G       ++ 
Sbjct: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746

Query: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188
            I      +E E  + A  +  S  E EE + +IG+WFW G++   +P
Sbjct: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47
           A  KNK++       K    A  GA  ++     PV++ + +A              K +
Sbjct: 50  ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109

Query: 48  TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97
             S+T+ +A      +   V+K K ++E +E       S P+        F P   ++  
Sbjct: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169

Query: 98  SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147
           ++         T K EA  ++ F W   + +++S FW+G+E    F   N   +    + 
Sbjct: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227

Query: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192
               E    A+   RS   +E         E+E+V   WFW  D T+       DPN + 
Sbjct: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282

Query: 193 VSRIVKPQPVY 203
            SR    + VY
Sbjct: 283 -SRFRSKKEVY 292



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%)

Query: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156
           C   AG  +W    EE    +NSWFW         S K  KPE  IG+ + A E     G
Sbjct: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734

Query: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195
              K +   EEE    +I +WFW+ D+   +   +  SR
Sbjct: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%)

Query: 97  TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148
           T   C+ E   D    A EE  I  SWFW   EA      NS S+  DK E  I      
Sbjct: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649

Query: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179
           EE  ++   G  C+  +GAEE                           EEEE+++ +WFW
Sbjct: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54
           M G + ++ AQ K EKK   +   GA  E +   VVRP  +T+A+    A+ K  SK   
Sbjct: 1   MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60

Query: 55  VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104
            A  K  +     A  K  A + P +  K        P+ G E  S T +N         
Sbjct: 61  GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120

Query: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158
              TD+   A        +     E  N    SF  +    + G Q      E    G+ 
Sbjct: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175

Query: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190
           C PR  +++E   N    W        FW GD+ +   +P
Sbjct: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215


>gi|103472136 G protein-coupled receptor associated sorting protein 1
            [Homo sapiens]
          Length = 1395

 Score =  236 bits (601), Expect = 5e-62
 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%)

Query: 2    AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56
            A T+ + R  A  EK+  + +  GA  E    +R  A + +K+  K   +   +      
Sbjct: 795  AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849

Query: 57   -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109
             E    +   V  E+K G   E  T+G       + + +AG+   E   S  + E    +
Sbjct: 850  EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909

Query: 110  WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142
            WFW G                  EE  + SWFW+ ++A     + +T   KPE      +
Sbjct: 910  WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969

Query: 143  GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199
            G+   AE+        G++C  R+ A+E+E   ++G+WFW GD+  F+ NP PV R +  
Sbjct: 970  GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027

Query: 200  QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252
                   E +   RP+ W EVT+     P      P++  FR   P EA+     +    
Sbjct: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085

Query: 253  EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312
              N    P         +     QP PE  F  DP  +++ EIR  +R +E    +  +C
Sbjct: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142

Query: 313  PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371
             C + E  + SEEFE+L+ L++   DP IH+I++IAMG+ +   F ++FI + GVV+LIE
Sbjct: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202

Query: 372  SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428
            +LL++PS  +R    + +I + PP  +     I+ ++  +C+ET+++ ++SP Q SG+++
Sbjct: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260

Query: 429  LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488
            +  LTT   +H +VANY S    LL++GN KTR  VLK+LLN+SEN    +++++ +A++
Sbjct: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320

Query: 489  ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547
                +FN++E   N+   +AIF NI  +I+K ++   D  +   L++ F +V++  + +
Sbjct: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%)

Query: 5   KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63
           K + RA+A T+++A  +A+A A++EA      +  T   A  ++    +A  E    V  
Sbjct: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431

Query: 64  NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112
             ++             T   + S P+T G+ +GD    A  E TS     EA +++   
Sbjct: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490

Query: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171
           A +E  I  SWFW GEE       +         + A  +E   G  C+ R+ +EEEE  
Sbjct: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548

Query: 172 NVIGNWFWEGDDTSFD 187
            VIG WFW G+    +
Sbjct: 549 -VIGPWFWSGEQVDIE 563



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49
           AG +   RA+ + +++A I    G+            E  A    RP+ K  A+A+A T 
Sbjct: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381

Query: 50  SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109
                    K  +K K  A  K+ A SE + L   +G +   A +ES+ +   +EA  ++
Sbjct: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425

Query: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161
                +E+ I SWFW  EEA  G   S+K+    D   IG  +    E+     GA+   
Sbjct: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485

Query: 162 RSGAEEEEEENVIGNWFWEGDDTS 185
            S    ++E+ +IG+WFW G++ +
Sbjct: 486 ESILAADDEQVIIGSWFWAGEEVN 509



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           MA  +  T ++++T ++  I + +G+E E+  V  P    R K    +G + D  +  + 
Sbjct: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285

Query: 61  VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111
            SK +V  E+  G+  E         GK A      +AG E+ +      K EA  D   
Sbjct: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345

Query: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168
            + +     S FW  EE  N+FS    K E  A+    EE +  A A  K  + +EEE  
Sbjct: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404

Query: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195
                                    E+E++IG+WFW  ++ S        SR
Sbjct: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%)

Query: 90  PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140
           P  G    S   + E   ++WFW+ +    EA I SW W  EE+     G       ++ 
Sbjct: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746

Query: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188
            I      +E E  + A  +  S  E EE + +IG+WFW G++   +P
Sbjct: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47
           A  KNK++       K    A  GA  ++     PV++ + +A              K +
Sbjct: 50  ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109

Query: 48  TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97
             S+T+ +A      +   V+K K ++E +E       S P+        F P   ++  
Sbjct: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169

Query: 98  SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147
           ++         T K EA  ++ F W   + +++S FW+G+E    F   N   +    + 
Sbjct: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227

Query: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192
               E    A+   RS   +E         E+E+V   WFW  D T+       DPN + 
Sbjct: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282

Query: 193 VSRIVKPQPVY 203
            SR    + VY
Sbjct: 283 -SRFRSKKEVY 292



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%)

Query: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156
           C   AG  +W    EE    +NSWFW         S K  KPE  IG+ + A E     G
Sbjct: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734

Query: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195
              K +   EEE    +I +WFW+ D+   +   +  SR
Sbjct: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%)

Query: 97  TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148
           T   C+ E   D    A EE  I  SWFW   EA      NS S+  DK E  I      
Sbjct: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649

Query: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179
           EE  ++   G  C+  +GAEE                           EEEE+++ +WFW
Sbjct: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54
           M G + ++ AQ K EKK   +   GA  E +   VVRP  +T+A+    A+ K  SK   
Sbjct: 1   MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60

Query: 55  VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104
            A  K  +     A  K  A + P +  K        P+ G E  S T +N         
Sbjct: 61  GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120

Query: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158
              TD+   A        +     E  N    SF  +    + G Q      E    G+ 
Sbjct: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175

Query: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190
           C PR  +++E   N    W        FW GD+ +   +P
Sbjct: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215


>gi|51702248 G protein-coupled receptor associated sorting protein 2
           [Homo sapiens]
          Length = 838

 Score =  231 bits (588), Expect = 2e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442

Query: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500

Query: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556

Query: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616

Query: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674

Query: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734

Query: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794

Query: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138

Query: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198

Query: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258

Query: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 64/281 (22%), Positives = 105/281 (37%), Gaps = 65/281 (23%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--------------ATGVVRP--------VA 38
           M G + +  AQAK EKKA  +  AG ERE              AT   RP         A
Sbjct: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60

Query: 39  KTRAKAKAKTGSKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAG----- 93
           + + +A+A +G++     ++   ++ K  A+   GA   PKT  +A+G    K       
Sbjct: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGA--RPKTDARAVGGARSKTDAKAIP 118

Query: 94  ----NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAE 149
                +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   
Sbjct: 119 GARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNV 178

Query: 150 ELEPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FW 179
           + E   G                      C  R  A  EE  N  G W          FW
Sbjct: 179 DAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFW 237

Query: 180 EGDDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219
            G++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 238 TGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392

Query: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216
              + S +      S I + +P  E         W+E
Sbjct: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426


>gi|19923967 G protein-coupled receptor associated sorting protein 2
           [Homo sapiens]
          Length = 838

 Score =  231 bits (588), Expect = 2e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442

Query: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500

Query: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556

Query: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616

Query: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674

Query: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734

Query: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794

Query: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138

Query: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198

Query: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258

Query: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 64/281 (22%), Positives = 105/281 (37%), Gaps = 65/281 (23%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--------------ATGVVRP--------VA 38
           M G + +  AQAK EKKA  +  AG ERE              AT   RP         A
Sbjct: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60

Query: 39  KTRAKAKAKTGSKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAG----- 93
           + + +A+A +G++     ++   ++ K  A+   GA   PKT  +A+G    K       
Sbjct: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGA--RPKTDARAVGGARSKTDAKAIP 118

Query: 94  ----NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAE 149
                +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   
Sbjct: 119 GARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNV 178

Query: 150 ELEPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FW 179
           + E   G                      C  R  A  EE  N  G W          FW
Sbjct: 179 DAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFW 237

Query: 180 EGDDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219
            G++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 238 TGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392

Query: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216
              + S +      S I + +P  E         W+E
Sbjct: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426


>gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens]
          Length = 558

 Score =  213 bits (541), Expect = 5e-55
 Identities = 169/553 (30%), Positives = 272/553 (49%), Gaps = 67/553 (12%)

Query: 10  AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV------SK 63
           A A+   K   +A A AE +   V +  A   A  +  T +  +A+A  + V      +K
Sbjct: 26  ATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTK 85

Query: 64  NKVVAETKEGALSE----PKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATI 119
            +V+ ETK   L+E    P+T  KAM            S+  K+E    A      EA I
Sbjct: 86  TRVMVETKTKPLAERSIVPQTKSKAMP-------MSRVSTVTKSEVKVVAVI----EANI 134

Query: 120 NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179
            S           ++  +DK   G++    E E + G        + +E+EEN+  +WFW
Sbjct: 135 RS-----------YAKSHDKANTGSRPDRRE-ETSIGMK------SSDEDEENIC-SWFW 175

Query: 180 EGDDTS----FDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRS 235
            G++ S    F P  +   ++ KP P  +I EK +P     +TI     A + A      
Sbjct: 176 TGEEPSVGSWFWPEEETSLQVYKPLP--KIQEKPKPTHKPTLTIKQKVIAWSRA------ 227

Query: 236 QAPSEASPPSYIVLASAEENACSLPVA---TACRPSRNTRSCSQPIPECRFDSDPCIQTI 292
                     YIVL   E    SLP     T       T    +P+ +      P  QT+
Sbjct: 228 ---------RYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTL 278

Query: 293 DEIRRQIRIREVNGIKPFACPCKMECY-MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVH 351
            EI++QIR RE  G  P AC CK   + ++ +EF+KLV+LLK T DP IH+IA + MG+ 
Sbjct: 279 AEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGIS 338

Query: 352 NVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCK 410
             +PF Q+ I++VG+  +IE+L++ P+ +     +  ++  S   E  +  E ++  +CK
Sbjct: 339 PAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCK 398

Query: 411 ETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLN 470
             +S PLNSP Q +GLK+LG L+  F  HY++ +Y  +   LL+ G+ KT+  VLK+   
Sbjct: 399 GIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458

Query: 471 MSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLS 529
           +S+N    R++I+ K L++L   FN+ E+KAN+++ + IF NI    + K  +   +  +
Sbjct: 459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFT 518

Query: 530 YNTLMAIFREVKE 542
            + L++IF+E K+
Sbjct: 519 KSELISIFQEAKQ 531



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 33/158 (20%)

Query: 4   TKNKTRAQAKTEKKAAIQAKAG----------AEREATGVVRPVAKTR--AKAKAKTGSK 51
           T+ +  A+A+ + ++  QAKAG            REA  V R V K     K +    +K
Sbjct: 34  TQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETK 93

Query: 52  TDAVAEMKAV------------------SKNKVVAETKEGALSEPKTLGKAMGDFTPKAG 93
           T  +AE   V                  S+ KVVA  +    S  K+  KA     P   
Sbjct: 94  TKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRR 153

Query: 94  NEST---SSTCKNEAGTDAWFWAGEEATINSWFWNGEE 128
            E++    S+ ++E    +WFW GEE ++ SWFW  EE
Sbjct: 154 EETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEE 191


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score =  181 bits (459), Expect = 2e-45
 Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)

Query: 14   TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
            TE+KA I ++   + EAT   R  A        +  A+ KA +GS  +++ VA M +   
Sbjct: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900

Query: 64   NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
             +  A  + GA +E      A       AG  +   T   E+G   W W G+  T+ S  
Sbjct: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957

Query: 124  WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
              GEEAG    T      +   V  +EL   +  D           EE  + + FW   E
Sbjct: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001

Query: 181  GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
              +T    + K  S          I +K       ++  W  A        G  + +  +
Sbjct: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053

Query: 241  ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
            ++P      A A++++ S  +     P     S    +   E +F   S+      DE R
Sbjct: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108

Query: 297  RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
            +Q R  E    +P++C CK E  MD  + EKL+ +++ T DP +H+IA  A+     + +
Sbjct: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166

Query: 357  AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
            + E +  VG +++IESLL+ P P +R+K +  LN  S   E  RK++ ++  +C++T+++
Sbjct: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226

Query: 416  PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
            PLNS  Q +GL+++  LT    + ++V NY SE   LL+ G+ +T++ VL +LLN S+NP
Sbjct: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286

Query: 476  TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
            +  +D++   A  +L  IF++KE K N+++ +++F NI  H  R+      D  S N+L 
Sbjct: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346

Query: 535  AIFREVK 541
             +F+  K
Sbjct: 2347 FLFQRPK 2353



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 5   KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
           K K R    T  K  A +  KA    ++ G   P  + +A+ KAK   KT    +MK  +
Sbjct: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640

Query: 63  KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
           + +   +T   AL + +  G+   + T KAG ++    C
Sbjct: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
           MA +K +    +K + K    A  KAGA  + TG V+P     ++ +   G+K       
Sbjct: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824

Query: 59  KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
             V  + V   T + A   P+ +  + G+  P A N+   + ++  K EAG  A      
Sbjct: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882

Query: 116 EATINS 121
           +A  NS
Sbjct: 883 QAVANS 888



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
           +A ++ +    AK + KA + A  KA A   ATG V+P A   +  +   G+K       
Sbjct: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904

Query: 59  KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
            AVSK     +T+  A  +P+ +  + G+  P A N+
Sbjct: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)

Query: 1    MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
            + G KNK R  +     A  +A+AGA  +  G  +P A   ++++   G++        A
Sbjct: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106

Query: 61   VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
            V K    A T+  A  +P+ +  + G+  P A ++S S+                     
Sbjct: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164

Query: 100  TCKNEAGTDAWFWAGEEATINSWFWNG 126
            T ++E G+        +  I+ ++WNG
Sbjct: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)

Query: 10   AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
            A+ K +  + + +KAGA  +  G  +P     ++ +   G++        A+SK    AE
Sbjct: 976  ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031

Query: 70   TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
               G +   + + +    G+  P A N+   ++++  K EAG D    A  +A  NS
Sbjct: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)

Query: 1    MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
            + G KNK +          + +KAGA  +  G  +P     ++ +   G++         
Sbjct: 933  LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986

Query: 61   VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
            VSK     +T   A  +P+ +  +  +  P A N+   ++++  K EAG
Sbjct: 987  VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 16/63 (25%), Positives = 31/63 (49%)

Query: 7   KTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKV 66
           KT+ Q +   +   ++  GAE E       + +  ++AKA  G++ +  +E K V+   V
Sbjct: 158 KTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLV 217

Query: 67  VAE 69
           + E
Sbjct: 218 MTE 220



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 2/90 (2%)

Query: 4   TKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSK 63
           T    +  A  + +A IQ +  A+++A   V   A+   +      SK    A+M+A ++
Sbjct: 436 TNAMCKVGAGADVRACIQPQTVAKKQAE--VTSGARVDGRGNTNVISKAITGADMRAAAQ 493

Query: 64  NKVVAETKEGALSEPKTLGKAMGDFTPKAG 93
            + VA T   A+S+ K   +   +   KAG
Sbjct: 494 PQAVASTHAEAMSDAKVKNRGNPNAMTKAG 523



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV 61
           A  KN+    A T+  A    +A ++ EA    R  ++      AK G  TD    M + 
Sbjct: 508 AKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTD----MLSC 563

Query: 62  SKNKVVAETKEGALSEPKTLGKAMGDFTPKAG 93
           ++ ++VA  +   LS+ K   +   +  PK G
Sbjct: 564 TQPQLVASVQADTLSDGKIKVRGNVNTMPKEG 595



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 57/227 (25%), Positives = 85/227 (37%), Gaps = 50/227 (22%)

Query: 1    MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKT--GS 50
            M G    + + A  E +A+I + +GA  +A G++R  A        K+ A A+A+   G 
Sbjct: 1211 MDGDWENSVSWADDENEASIGSWSGASDKA-GIIRSWAVACDETSVKSWAGARAENVVGI 1269

Query: 51   KTDAVAEMKAVSKNKVVAETKEGALSEPKTLG--------KAMGDFTPKAGNESTSST-C 101
             T A A  +A        +T EG  +  K  G        +A G     AGN++      
Sbjct: 1270 GTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWA 1329

Query: 102  KNEAGTDAW--------FWAGEEATINSWF----------WNGEEAGNSFSTKN-----D 138
              +A   +W         W GEEA   SW           W G  AGN  S        D
Sbjct: 1330 AGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVD 1389

Query: 139  KPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTS 185
            +   G+     +    +G   KPR     E++ +  G+W   G   S
Sbjct: 1390 QAGGGSWAGTSD---QSGGGSKPRF----EDQASGEGSWAGAGGQAS 1429



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA----KAKTGSKTDAVA 56
           + G +++T A  + E K   Q + GAE  A        +T+A A    +A + +K    A
Sbjct: 142 VVGVQSQTLAINEAEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGA 201

Query: 57  EMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSST 100
           E +  S++KVVA T    ++E  TL +        A  E+ + T
Sbjct: 202 EPETQSESKVVAGTL--VMTEAVTLTEVKAKAREVAMKEAVTQT 243



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 8/95 (8%)

Query: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
           + G KNK R            +KAGA  +  G  +P A   ++ +   G+K         
Sbjct: 893 LPGAKNKVRGNWNAV------SKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNV 946

Query: 61  VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
           VSK     +T     ++P+ L  +  +  P A N+
Sbjct: 947 VSKAGAREDTV--GSTQPQVLASSQRETLPGARNK 979



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 25/91 (27%), Positives = 33/91 (36%), Gaps = 18/91 (19%)

Query: 2   AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAV 61
           A T+ K       EK+  I      + E   V R VAK                  M A 
Sbjct: 276 AMTQTKAETHILAEKETEINRVMVTQSETLAVPREVAK------------------MGAT 317

Query: 62  SKNKVVAETKEGALSEPKTLGKAMGDFTPKA 92
           +K  +V ETK  AL E  ++ K   +  P A
Sbjct: 318 NKTGIVDETKTRALEETVSVAKTQSEARPGA 348


>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score =  122 bits (306), Expect = 8e-28
 Identities = 65/218 (29%), Positives = 132/218 (60%), Gaps = 1/218 (0%)

Query: 302 REVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFI 361
           R    ++  A P   +  +  +E +K++ L++ +  P I + A IA+G +  + F ++ I
Sbjct: 100 RARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDII 159

Query: 362 NEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSP 420
            ++G + ++  +L+   P +++K +I LN  S + E QR++++++  +C +T++  LNS 
Sbjct: 160 RDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSS 219

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
            Q +GL++L  +T    + +++AN  S+ F L S+GN +T+  VLKLLLN++ENP   R+
Sbjct: 220 VQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRE 279

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR 518
           ++  +  ++L  +FN+KE K  ++  + IF NI ++ +
Sbjct: 280 LLRAQVPSSLGSLFNKKENKEVILKLLVIFENINDNFK 317


>gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score =  122 bits (306), Expect = 8e-28
 Identities = 65/218 (29%), Positives = 132/218 (60%), Gaps = 1/218 (0%)

Query: 302 REVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFI 361
           R    ++  A P   +  +  +E +K++ L++ +  P I + A IA+G +  + F ++ I
Sbjct: 100 RARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDII 159

Query: 362 NEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSP 420
            ++G + ++  +L+   P +++K +I LN  S + E QR++++++  +C +T++  LNS 
Sbjct: 160 RDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSS 219

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
            Q +GL++L  +T    + +++AN  S+ F L S+GN +T+  VLKLLLN++ENP   R+
Sbjct: 220 VQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRE 279

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR 518
           ++  +  ++L  +FN+KE K  ++  + IF NI ++ +
Sbjct: 280 LLRAQVPSSLGSLFNKKENKEVILKLLVIFENINDNFK 317


>gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score =  122 bits (306), Expect = 8e-28
 Identities = 65/218 (29%), Positives = 132/218 (60%), Gaps = 1/218 (0%)

Query: 302 REVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFI 361
           R    ++  A P   +  +  +E +K++ L++ +  P I + A IA+G +  + F ++ I
Sbjct: 100 RARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDII 159

Query: 362 NEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSP 420
            ++G + ++  +L+   P +++K +I LN  S + E QR++++++  +C +T++  LNS 
Sbjct: 160 RDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSS 219

Query: 421 GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD 480
            Q +GL++L  +T    + +++AN  S+ F L S+GN +T+  VLKLLLN++ENP   R+
Sbjct: 220 VQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRE 279

Query: 481 MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR 518
           ++  +  ++L  +FN+KE K  ++  + IF NI ++ +
Sbjct: 280 LLRAQVPSSLGSLFNKKENKEVILKLLVIFENINDNFK 317


>gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens]
          Length = 453

 Score =  119 bits (297), Expect = 9e-27
 Identities = 68/232 (29%), Positives = 134/232 (57%), Gaps = 2/232 (0%)

Query: 310 FACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTL 369
           F  P K++  + + + +K++++L+ T DP I ++A + +G +  + F Q  I E+G V +
Sbjct: 192 FNFPYKIDDILSAPDLQKVLNILERTNDPFIQEVALVTLGNNAAYSFNQNAIRELGGVPI 251

Query: 370 IESLLSFPSPEMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428
           I  L+    P +R+KT   LN  S + E Q KI+ ++  +C +TM   L+S  Q +GL++
Sbjct: 252 IAKLIKTKDPIIREKTYNALNNLSVNAENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRL 311

Query: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488
           L  +T    + ++++  F + F LL  GN  T+  ++KL++N +ENP   R++++ K  +
Sbjct: 312 LTNMTVTNHYQHLLSYSFPDFFALLFLGNHFTKIQIMKLIINFTENPAMTRELVSCKVPS 371

Query: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIR-KGSIVVVDHLSYNTLMAIFRE 539
            L  +FN++  +  L++ + +F NI ++I+ +G        S ++L  +F+E
Sbjct: 372 ELISLFNKEWDREILLNILTLFENINDNIKNEGLASSRKEFSRSSLFFLFKE 423


>gi|238776793 SVH protein isoform b [Homo sapiens]
          Length = 308

 Score =  112 bits (281), Expect = 7e-25
 Identities = 62/200 (31%), Positives = 119/200 (59%), Gaps = 1/200 (0%)

Query: 320 MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSP 379
           +++E+ +KL+ LL+ST DP+I + A I +G +      Q  I E+G + ++ + ++  + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 380 EMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVH 438
            +++K +  LN  S + E Q KI++++  +C++  S PLNS  Q +GL +L  +T    H
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177

Query: 439 HYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKE 498
            +++ +Y ++LF +L +GN  T+  VLKLLLN+SENP     ++  +  ++   +++   
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 237

Query: 499 AKANLVSGVAIFINIKEHIR 518
           AK  L+  + +F NIK  ++
Sbjct: 238 AKEILLRVLTLFQNIKNCLK 257


>gi|31377663 SVH protein isoform a [Homo sapiens]
          Length = 343

 Score =  112 bits (281), Expect = 7e-25
 Identities = 62/200 (31%), Positives = 119/200 (59%), Gaps = 1/200 (0%)

Query: 320 MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSP 379
           +++E+ +KL+ LL+ST DP+I + A I +G +      Q  I E+G + ++ + ++  + 
Sbjct: 93  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 152

Query: 380 EMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVH 438
            +++K +  LN  S + E Q KI++++  +C++  S PLNS  Q +GL +L  +T    H
Sbjct: 153 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 212

Query: 439 HYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKE 498
            +++ +Y ++LF +L +GN  T+  VLKLLLN+SENP     ++  +  ++   +++   
Sbjct: 213 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 272

Query: 499 AKANLVSGVAIFINIKEHIR 518
           AK  L+  + +F NIK  ++
Sbjct: 273 AKEILLRVLTLFQNIKNCLK 292


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 57/236 (24%), Positives = 128/236 (54%), Gaps = 7/236 (2%)

Query: 284 DSDPCIQTIDEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKI 343
           DS+P  Q     RR + +++    +PF  P +++  +   +  K+++LL+ + DP I ++
Sbjct: 353 DSEPETQRRGRGRRPVAMQK----RPF--PYEIDEILGVRDLRKVLALLQKSDDPFIQQV 406

Query: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGD-ERQRKIE 402
           A + +  +  +   QE I ++G + +I ++++   P +++K ++ +N  S + E Q +++
Sbjct: 407 ALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQ 466

Query: 403 LHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRN 462
           +++  +  + M+  LNS  Q  GLK L  +T    + +++ N  +  F LLS G  K + 
Sbjct: 467 VYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKV 526

Query: 463 LVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR 518
            +LK+L N +ENP   + +++ +  A+   ++N       L++ + +F  I +++R
Sbjct: 527 EILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLR 582


>gi|29540562 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 57/236 (24%), Positives = 128/236 (54%), Gaps = 7/236 (2%)

Query: 284 DSDPCIQTIDEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKI 343
           DS+P  Q     RR + +++    +PF  P +++  +   +  K+++LL+ + DP I ++
Sbjct: 353 DSEPETQRRGRGRRPVAMQK----RPF--PYEIDEILGVRDLRKVLALLQKSDDPFIQQV 406

Query: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGD-ERQRKIE 402
           A + +  +  +   QE I ++G + +I ++++   P +++K ++ +N  S + E Q +++
Sbjct: 407 ALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQ 466

Query: 403 LHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRN 462
           +++  +  + M+  LNS  Q  GLK L  +T    + +++ N  +  F LLS G  K + 
Sbjct: 467 VYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKV 526

Query: 463 LVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIR 518
            +LK+L N +ENP   + +++ +  A+   ++N       L++ + +F  I +++R
Sbjct: 527 EILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLR 582


>gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo
           sapiens]
          Length = 284

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 44/143 (30%), Positives = 88/143 (61%), Gaps = 1/143 (0%)

Query: 320 MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSP 379
           +++E+ +KL+ LL+ST DP+I + A I +G +      Q  I E+G + ++ + ++  + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 380 EMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVH 438
            +++K +  LN  S + E Q KI++++  +C++  S PLNS  Q +GL++L  +T    H
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177

Query: 439 HYIVANYFSELFHLLSSGNCKTR 461
            +++ +Y ++LF +L +GN  T+
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK 200


>gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo
           sapiens]
          Length = 284

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 44/143 (30%), Positives = 87/143 (60%), Gaps = 1/143 (0%)

Query: 320 MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSP 379
           +++E+ +KL+ LL+ST DP+I + A I +G +      Q  I E+G + ++ + ++  + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 380 EMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVH 438
            ++ K +  LN  S + E Q KI++++  +C++  S PLNS  Q +GL++L  +T    H
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177

Query: 439 HYIVANYFSELFHLLSSGNCKTR 461
            +++ +Y ++LF +L +GN  T+
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK 200


>gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo
           sapiens]
          Length = 284

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 44/143 (30%), Positives = 87/143 (60%), Gaps = 1/143 (0%)

Query: 320 MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSP 379
           +++E+ +KL+ LL+ST DP+I + A I +G +      Q  I E+G + ++ + ++  + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 380 EMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVH 438
            ++ K +  LN  S + E Q KI++++  +C++  S PLNS  Q +GL++L  +T    H
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177

Query: 439 HYIVANYFSELFHLLSSGNCKTR 461
            +++ +Y ++LF +L +GN  T+
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK 200


>gi|238776797 SVH protein isoform e [Homo sapiens]
          Length = 284

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 44/143 (30%), Positives = 87/143 (60%), Gaps = 1/143 (0%)

Query: 320 MDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSP 379
           +++E+ +KL+ LL+ST DP+I + A I +G +      Q  I E+G + ++ + ++  + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 380 EMRKKTVITLNPPSGD-ERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVH 438
            +++K +  LN  S + E Q KI++++  +C++  S PLNS  Q +GL +L  +T    H
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177

Query: 439 HYIVANYFSELFHLLSSGNCKTR 461
            +++ +Y ++LF +L +GN  T+
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK 200


>gi|169217162 PREDICTED: similar to armadillo repeat containing,
           X-linked 6 [Homo sapiens]
          Length = 200

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 40/141 (28%), Positives = 77/141 (54%), Gaps = 4/141 (2%)

Query: 355 PFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMS 414
           PF+Q+  + +  +++  +    P P +R+      N  +  E Q +I++++  +C+ET+S
Sbjct: 48  PFSQDINSHLASLSMARNTSPTPDPTVREALCAPDNLNASIESQGQIKMYINEVCRETVS 107

Query: 415 FPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSEL-FHLLSSGNCKTRNLVLKLLLNMSE 473
              NS  QQ+GL +L  +T   V + ++A   S+L F L+S G+   +  VLK L+ +SE
Sbjct: 108 RCCNSFLQQAGLNLLISMT---VINNMLAKSASDLKFPLISEGSGCAKVQVLKPLMGLSE 164

Query: 474 NPTAARDMINMKALAALKLIF 494
            P  A +++  + L +   +F
Sbjct: 165 KPVLAGELVGAQMLFSFMSLF 185


>gi|169216354 PREDICTED: similar to armadillo repeat containing,
           X-linked 6, partial [Homo sapiens]
          Length = 189

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 40/141 (28%), Positives = 77/141 (54%), Gaps = 4/141 (2%)

Query: 355 PFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMS 414
           PF+Q+  + +  +++  +    P P +R+      N  +  E Q +I++++  +C+ET+S
Sbjct: 48  PFSQDINSHLASLSMARNTSPTPDPTVREALCAPDNLNASIESQGQIKMYINEVCRETVS 107

Query: 415 FPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSEL-FHLLSSGNCKTRNLVLKLLLNMSE 473
              NS  QQ+GL +L  +T   V + ++A   S+L F L+S G+   +  VLK L+ +SE
Sbjct: 108 RCCNSFLQQAGLNLLISMT---VINNMLAKSASDLKFPLISEGSGCAKVQVLKPLMGLSE 164

Query: 474 NPTAARDMINMKALAALKLIF 494
            P  A +++  + L +   +F
Sbjct: 165 KPVLAGELVGAQMLFSFMSLF 185


>gi|169216627 PREDICTED: similar to armadillo repeat containing,
           X-linked 6 [Homo sapiens]
          Length = 200

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 40/141 (28%), Positives = 77/141 (54%), Gaps = 4/141 (2%)

Query: 355 PFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMS 414
           PF+Q+  + +  +++  +    P P +R+      N  +  E Q +I++++  +C+ET+S
Sbjct: 48  PFSQDINSHLASLSMARNTSPTPDPTVREALCAPDNLNASIESQGQIKMYINEVCRETVS 107

Query: 415 FPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSEL-FHLLSSGNCKTRNLVLKLLLNMSE 473
              NS  QQ+GL +L  +T   V + ++A   S+L F L+S G+   +  VLK L+ +SE
Sbjct: 108 RCCNSFLQQAGLNLLISMT---VINNMLAKSASDLKFPLISEGSGCAKVQVLKPLMGLSE 164

Query: 474 NPTAARDMINMKALAALKLIF 494
            P  A +++  + L +   +F
Sbjct: 165 KPVLAGELVGAQMLFSFMSLF 185


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,968,400
Number of Sequences: 37866
Number of extensions: 1019646
Number of successful extensions: 3106
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 2662
Number of HSP's gapped (non-prelim): 218
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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