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Search of human proteins with 215982791
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215982791 myosin VA isoform 1 [Homo sapiens]
(1855 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215982791 myosin VA isoform 1 [Homo sapiens] 3676 0.0
gi|215982794 myosin VA isoform 2 [Homo sapiens] 3606 0.0
gi|122937345 myosin VB [Homo sapiens] 2295 0.0
gi|153945715 myosin VC [Homo sapiens] 1787 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 617 e-176
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 608 e-173
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 603 e-172
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 601 e-171
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 597 e-170
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 596 e-170
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 596 e-170
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 594 e-169
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 594 e-169
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 593 e-169
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 593 e-169
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 592 e-169
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 590 e-168
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 586 e-167
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 585 e-166
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 582 e-166
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 582 e-166
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 582 e-166
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 582 e-166
gi|122937512 myosin VIIB [Homo sapiens] 572 e-162
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 564 e-160
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 542 e-153
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 541 e-153
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 534 e-151
gi|154354979 myosin X [Homo sapiens] 531 e-150
gi|194328685 myosin IB isoform 1 [Homo sapiens] 520 e-147
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 3676 bits (9532), Expect = 0.0
Identities = 1855/1855 (100%), Positives = 1855/1855 (100%)
Query: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
Query: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG
Sbjct: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
Query: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
Sbjct: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
Query: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR
Sbjct: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
Query: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD
Sbjct: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN
Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE
Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 481 QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
Sbjct: 481 QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
Query: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS
Sbjct: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600
Query: 601 PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660
PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC
Sbjct: 601 PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660
Query: 661 IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL 720
IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
Sbjct: 661 IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL 720
Query: 721 SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW 780
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW
Sbjct: 721 SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW 780
Query: 781 LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA
Sbjct: 781 LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
Query: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM 900
TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
Sbjct: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM 900
Query: 901 AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE 960
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE
Sbjct: 901 AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE 960
Query: 961 TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET 1020
TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET
Sbjct: 961 TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET 1020
Query: 1021 EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN 1080
EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
Sbjct: 1021 EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN 1080
Query: 1081 LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT 1140
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT
Sbjct: 1081 LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT 1140
Query: 1141 EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE
Sbjct: 1141 EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
Query: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD 1260
LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
Sbjct: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD 1260
Query: 1261 VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNR 1320
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNR
Sbjct: 1261 VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNR 1320
Query: 1321 SSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR 1380
SSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR
Sbjct: 1321 SSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR 1380
Query: 1381 QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI
Sbjct: 1381 QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
Query: 1441 GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV 1500
GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV
Sbjct: 1441 GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV 1500
Query: 1501 AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN 1560
AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN
Sbjct: 1501 AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN 1560
Query: 1561 TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI 1620
TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI
Sbjct: 1561 TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI 1620
Query: 1621 LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM 1680
LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM
Sbjct: 1621 LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM 1680
Query: 1681 DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA 1740
DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA
Sbjct: 1681 DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA 1740
Query: 1741 KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF 1800
KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF
Sbjct: 1741 KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF 1800
Query: 1801 IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 1855
IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV
Sbjct: 1801 IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 1855
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 3606 bits (9350), Expect = 0.0
Identities = 1828/1855 (98%), Positives = 1828/1855 (98%), Gaps = 27/1855 (1%)
Query: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
Query: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG
Sbjct: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
Query: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
Sbjct: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
Query: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR
Sbjct: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
Query: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD
Sbjct: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN
Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE
Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 481 QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
Sbjct: 481 QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
Query: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS
Sbjct: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600
Query: 601 PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660
PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC
Sbjct: 601 PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660
Query: 661 IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL 720
IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
Sbjct: 661 IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL 720
Query: 721 SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW 780
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW
Sbjct: 721 SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW 780
Query: 781 LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA
Sbjct: 781 LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
Query: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM 900
TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
Sbjct: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM 900
Query: 901 AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE 960
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE
Sbjct: 901 AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE 960
Query: 961 TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET 1020
TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET
Sbjct: 961 TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET 1020
Query: 1021 EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN 1080
EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
Sbjct: 1021 EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN 1080
Query: 1081 LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT 1140
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT
Sbjct: 1081 LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT 1140
Query: 1141 EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE
Sbjct: 1141 EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
Query: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD 1260
LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
Sbjct: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD 1260
Query: 1261 VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNR 1320
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKET
Sbjct: 1261 VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKET-- 1318
Query: 1321 SSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR 1380
NRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR
Sbjct: 1319 -------------------------NRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR 1353
Query: 1381 QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI
Sbjct: 1354 QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1413
Query: 1441 GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV 1500
GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV
Sbjct: 1414 GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV 1473
Query: 1501 AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN 1560
AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN
Sbjct: 1474 AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN 1533
Query: 1561 TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI 1620
TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI
Sbjct: 1534 TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI 1593
Query: 1621 LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM 1680
LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM
Sbjct: 1594 LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM 1653
Query: 1681 DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA 1740
DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA
Sbjct: 1654 DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA 1713
Query: 1741 KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF 1800
KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF
Sbjct: 1714 KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF 1773
Query: 1801 IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 1855
IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV
Sbjct: 1774 IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 1828
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 2295 bits (5946), Expect = 0.0
Identities = 1170/1868 (62%), Positives = 1456/1868 (77%), Gaps = 33/1868 (1%)
Query: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
M+ ELY++ RVWIPDP+EVW+SAEL KDYK GDK L L LE+ LEY +D + +LP
Sbjct: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60
Query: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
LRNPDILVGENDLTALSYLHEPAVLHNL+VRF++S IYTYCGIVLVAINPYEQLPIYG
Sbjct: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120
Query: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
+D+I YSGQNMGDMDPHIFAVAEEAYKQMARDE+NQSIIVSGESGAGKTVSAKYAMRYF
Sbjct: 121 QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180
Query: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
ATV GSASE N+EEKVLAS+PIME+IGNAKTTRNDNSSRFGKYI+IGFDKRY IIGANMR
Sbjct: 181 ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
Query: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
TYLLEKSRVVFQA++ERNYHIFYQLCA+A LPEFK L L +A++F YT QGG IEGVD
Sbjct: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCI 359
DA++ TRQA TLLG+ ESHQM IF+I+A ILHLG+V RD DSC+I P+ L
Sbjct: 301 DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360
Query: 360 FCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNV 419
FC L+GV++ +M HWLCHRKL T +ETY+K +S Q NAR+ALAKHIYA+LF WIV+++
Sbjct: 361 FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420
Query: 420 NQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479
N+ALH+++KQHSFIGVLDIYGFETFE+NSFEQFCINYANEKLQQQFN HVFKLEQEEYMK
Sbjct: 421 NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
Query: 480 EQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
EQIPWTLIDFYDNQPCI+LIE+KLGILDLLDEECK+PKGTD WAQKLY+ H + F+
Sbjct: 481 EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQ 539
Query: 540 KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599
KPR+SN AFII HFADKVEY +GFLEKN+DTV+EEQI +LK+SKF ++ +LF DD+
Sbjct: 540 KPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDK--- 596
Query: 600 SPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVR 659
P AT+ G+ ++ + + KEHKKTVGHQFR SLHLLMETLNATTPHYVR
Sbjct: 597 DPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVR 656
Query: 660 CIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDV 719
CIKPND K PF FD KRAVQQLRACGVLETIRISAAG+PSRW Y +FF+RYRVL+K++++
Sbjct: 657 CIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKREL 716
Query: 720 L-SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIR 778
+D+K C++VLE LI D DK+QFG+TKIFFRAGQVAYLEKLRADK R A I IQKT+R
Sbjct: 717 ANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVR 776
Query: 779 GWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRR 838
GWL + KY R++ A +T+QRY RG+ AR A+ LRR +AA ++QK++RM R+ Y+ R
Sbjct: 777 GWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836
Query: 839 AATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRR 898
A +V+Q++ R R YR++L EHKA IQK VRGW+AR H++R A I +QC FR
Sbjct: 837 RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896
Query: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
+ A+RELK L+IEARS E K+L++GMENK++QLQRK+DEQNK++K L E+L+ Y
Sbjct: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956
Query: 959 SETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQ 1018
E E+L+ +L Q S E L LQEE+ LR +L++ SE+K +E+ R K
Sbjct: 957 MEVERLKKELVHYQQSPGE-----DTSLRLQEEVESLRTELQRAHSERKILEDAHSREKD 1011
Query: 1019 ETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
E + V++L++EN LLK EKE LN++I+ Q+K+ E + + E + EL+ +ER RY
Sbjct: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKELE--EERSRY 1067
Query: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE----YIFSSEIAEME 1134
QNL+ E+S+LE+RYD+L++EMT++ PGH+R S SS ES+ I +SEI + E
Sbjct: 1068 QNLVKEYSQLEQRYDNLRDEMTIIKQT--PGHRRNPSNQSSLESDSNYPSISTSEIGDTE 1125
Query: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP 1194
D + EE +K +DM++FLKLQKRV ELEQE++ +Q +L+++E+Q SK + E P
Sbjct: 1126 DALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQ--DSKKVQAEPP 1183
Query: 1195 QI-----RGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP-AYRVL 1248
Q A+L Y SLKRQELESENKKLKN+LNELRKA+++++ ++ G+P +Y +L
Sbjct: 1184 QTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLL 1243
Query: 1249 MEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEI 1308
+ QL EEL+VRKEEVLILR+Q+VS + + ++ + +K D+ +
Sbjct: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303
Query: 1309 AQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALR 1368
+AY G+ +TN S D+ LNEDGEL L Y+GLKQ RLLE+QLQ+Q HE E E L+
Sbjct: 1304 IEAYHGVCQTN-SKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLK 1362
Query: 1369 GEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRK 1428
++++LKEE ++QQQ Q L L PEA++E +Q EI+RLTNENLDL E +EK +K RK
Sbjct: 1363 AQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK 1422
Query: 1429 LKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLV 1488
LKKQLK++ KK +LE Q S + E R V + RKEKDFQGMLEY KEDE L+
Sbjct: 1423 LKKQLKIYMKKAQDLEAAQALAQSERK-RHELNRQVTVQRKEKDFQGMLEYHKEDEALLI 1481
Query: 1489 KNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRG 1548
+NL+ +LKP+ ++ +P LPAYIL+MC+RHADY NDD KV SLLTSTIN IKKVLKK
Sbjct: 1482 RNLVTDLKPQMLS-GTVPCLPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHN 1540
Query: 1549 DDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQ 1608
DDFE SFWLSNTCR LHCLKQYSG+EGFM NT++QNEHCL NFDL EYRQVLSDL+IQ
Sbjct: 1541 DDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQ 1600
Query: 1609 IYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD-EGTYTLDSILRQ 1667
IYQQL+++ E +LQPMIVS MLE+E+IQG+SGVKPTG RKR+SS+AD + +Y L++I+RQ
Sbjct: 1601 IYQQLIKIAEGVLQPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQ 1660
Query: 1668 LNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLE 1727
+N+FH+VMC G+DPE+I QV KQ+FY+I A+TLNNLLLRKD+CSWS GMQ+RYN+SQLE
Sbjct: 1661 MNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLE 1720
Query: 1728 EWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYT 1787
EWLR +NL SGA +T+EPLIQAAQLLQ+KKKT +DAEAICS+C +L+T QIVK+LNLYT
Sbjct: 1721 EWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYT 1780
Query: 1788 PVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASL 1847
P+NEFEERV+V+FIRTIQ +L++R D QLL+DAKH+FPV FPFNPSSL +++I IPA L
Sbjct: 1781 PLNEFEERVTVAFIRTIQAQLQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACL 1840
Query: 1848 GLGFISRV 1855
L F++ V
Sbjct: 1841 NLEFLNEV 1848
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 1787 bits (4629), Expect = 0.0
Identities = 965/1901 (50%), Positives = 1293/1901 (68%), Gaps = 205/1901 (10%)
Query: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
MA +ELYT++ RVWIPDPEEVWKSAE+ KDY+ GDKVL L LE+G +L+Y ++P++ LP
Sbjct: 1 MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPES--LP 58
Query: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
LRNPDILVGENDLTALSYLHEPAVLHNLR+RF +SKLIYTY GI+LVA+NPY+QLPIYG
Sbjct: 59 PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118
Query: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
+ II+AYSGQNMGDMDPHIFAVAEEAYKQMAR+ RNQSIIVSGESGAGKTVSA+YAMRYF
Sbjct: 119 DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178
Query: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
ATVS S S A+VE+KVLASNPI E++GNAKTTRNDNSSRFGKY EI FD++ +IIGANM
Sbjct: 179 ATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
Query: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
TYLLEKSRVVFQ+E ERNYHIFYQLCASA+ EFK L+LG+A+ FNYT+ GG+ VIEGV+
Sbjct: 239 TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
D EM T++ TLLG E QM +F+ILA ILHLGNV T+ + ++ L +F
Sbjct: 299 DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVF 358
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
C+L+G++ + WLC+RK+ T++ET +KP+++ QA NARDALAK IYA LF++IV+ +N
Sbjct: 359 CELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERIN 418
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
QAL + KQH+FIGVLDIYGFETF++NSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE
Sbjct: 419 QALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 478
Query: 481 QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540
IPWTLIDFYDNQP I+LIE+K+GIL+LLDEEC +P GTD+ W QKLYN +N+ LFEK
Sbjct: 479 DIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEK 538
Query: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS 600
PR+SN +F+IQHFADKVEY+CEGFLEKN+DTV++ +++L++SKF + FQ++ S
Sbjct: 539 PRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPS 598
Query: 601 PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC 660
P + + ++ + KP +K + TVG +FR+SL+LLMETLNATTPHYVRC
Sbjct: 599 PFGSMITVKS--AKQVIKPN-------SKHFRTTVGSKFRSSLYLLMETLNATTPHYVRC 649
Query: 661 IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM-KQKDV 719
IKPND K PF FD KR VQQLRACGVLETIRISA +PSRWTY EF+SRY +LM KQ+
Sbjct: 650 IKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELS 709
Query: 720 LSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRG 779
SD+K+ CK VL +LI D ++YQFGKTKIFFRAGQVAYLEKLR DKLR +C+ +QK +RG
Sbjct: 710 FSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRG 769
Query: 780 WLLRKKYLRMRKAAITMQRYVRGYQA---RCYAKFLRRTKAATIIQKYWRMYVVRRRYKI 836
WL RKK+LR R+AA+ +Q+Y RG Q A L+ AA IIQK+ R Y+VR Y++
Sbjct: 770 WLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQL 829
Query: 837 RRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCF 896
R ATI +Q+Y RGFLAR RYRK+L EHKAVI+QK R WLAR ++ ++ +Q +
Sbjct: 830 IRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTY 889
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956
R + +LQ+K+++QNK+ LVEKLT+L +
Sbjct: 890 R-------------------------------VQRLQKKLEDQNKENHGLVEKLTSLAAL 918
Query: 957 YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRY 1016
+ EK++ KL +LE+ + ++ EE RY
Sbjct: 919 RAGDVEKIQ----------------------------KLEAELEKAATHRRNYEEKGKRY 950
Query: 1017 KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDER- 1075
+ E+ ++ L++ N+ L+ +KE + ++ +E TE +++K+ TKQL D+ E
Sbjct: 951 RDAVEEKLAKLQKHNSELETQKEQIQLKL----QEKTEELKEKMDNLTKQLFDDVQKEER 1006
Query: 1076 ----------LRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
L+ Q+ + L+E LK+E + H+ + H +D
Sbjct: 1007 QRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDG---------- 1056
Query: 1126 FSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR 1185
+E+A + +T EK++ L + + ++K V + +K+ M++++ +Q+L
Sbjct: 1057 LKAEVARLSK-QVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLE 1112
Query: 1186 SKAKEEERPQIRGAELE-----------YESLKR-----------------QELESENKK 1217
S E+ R ++ +LE YE LK+ +E+E+ N K
Sbjct: 1113 SYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFK 1172
Query: 1218 ---LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLV 1274
L E+N L+K E++ + R + +LTS + + K+++ S+L
Sbjct: 1173 VVHLSQEINHLQKLFREENDIN------ESIRHEVTRLTSENMMIPDFKQQI----SELE 1222
Query: 1275 SQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGE 1334
QK+ ++ + L E +KMK K L+E + H E+
Sbjct: 1223 KQKQDLEIR-----------LNEQAEKMKGK---------LEELSNQ----LHRSQEE-- 1256
Query: 1335 LWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPE 1394
EG ++ L++Q H E E L +IQ ++E ++ ++ Q E
Sbjct: 1257 -----EGTQR------KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKK------QFETE 1299
Query: 1395 ARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPG 1454
+ ++ + + E +RLT EN DL E+L+ +D+ ++KL+ Q+K +K IG+
Sbjct: 1300 SEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKAN---------- 1349
Query: 1455 QIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILF 1514
V+ K++ GML+YK+EDE KL++NLIL+LKPRGV VN+IPGLPA+ILF
Sbjct: 1350 --------DVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILF 1401
Query: 1515 MCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGE 1574
MCVR+AD LND ++SL+ STIN IK+V+K+ +DFE +SFWLSNTC FL+CLKQYSGE
Sbjct: 1402 MCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGE 1461
Query: 1575 EGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHET 1634
E FMKHN+ +QN++CL NFDL+EYRQ+LSD+AI+IY Q + ++E +QP+IV GMLE+E+
Sbjct: 1462 EEFMKHNSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYES 1521
Query: 1635 IQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFY 1694
+QG+SG+KPTG RKR+SSI D YT+ S+L+QL+ F++ MCQ+G+DPEL++Q VKQ+F+
Sbjct: 1522 LQGISGLKPTGFRKRSSSIDDTDGYTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFF 1581
Query: 1695 IIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLL 1754
+IGA+TLN+L LRKDMCS KGMQIR N+S LEEWL+DKNL NS AKETLEPL QAA LL
Sbjct: 1582 LIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDKNLQNSLAKETLEPLSQAAWLL 1641
Query: 1755 QVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDS 1814
QVKK TD DA+ I C +L+ QI+K+LN YTP+++FE+RV+ SF+R +Q L R+DS
Sbjct: 1642 QVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFEKRVTPSFVRKVQALLNSREDS 1701
Query: 1815 PQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 1855
QL++D K++F VTFPF PS ALE IQIP+S LGF++R+
Sbjct: 1702 SQLMLDTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLNRL 1742
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 617 bits (1592), Expect = e-176
Identities = 452/1500 (30%), Positives = 752/1500 (50%), Gaps = 151/1500 (10%)
Query: 14 WIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEND 73
++PD +E + A++L + G KV+ E GK + D ++ NP D
Sbjct: 38 FVPDDKEEFVKAKILS--REGGKVIA-ETENGKTVTVKEDQVLQQ-----NPPKFDKIED 89
Query: 74 LTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMG 133
+ L++LHEPAVL NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 90 MAMLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRS 148
Query: 134 DMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG-------- 185
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFA+++
Sbjct: 149 EAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKD 208
Query: 186 --SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
+A++ +E++++ +NP +E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 209 NANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
Query: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDA 302
LEKSRV+FQ + ERNYHIFYQ+ ++ K ML + N ++ + QG V +DD+
Sbjct: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVAS-IDDS 327
Query: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
+E+ T A +LG + + G++++ I+H GN+ F + + P E
Sbjct: 328 EELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAY 387
Query: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
LMG++ ++ LCH ++ E K S Q + ALAK +Y K+FNW+V +N
Sbjct: 388 LMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINAT 447
Query: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
L + + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 448 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 507
Query: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
WT IDF D Q CI+LIE +GI+ +L+EEC PK TD T+ KLY+ HL K F+KP
Sbjct: 508 EWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKP 567
Query: 542 R----LSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
R F + H+A V+Y G+LEKNKD + E + + + S K++ LF
Sbjct: 568 RNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYAT 627
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
A + S S G G+ +TV R +L+ LM L T PH+
Sbjct: 628 ADTGDSGKSKG----------------GKKKGSSFQTVSALHRENLNKLMTNLRTTHPHF 671
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL---- 713
VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F RYR+L
Sbjct: 672 VRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVA 731
Query: 714 MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRI 773
+ + + RK T + +L L +D ++Y+FG TK+FF+AG + LE++R ++L R+
Sbjct: 732 IPEGQFIDSRKGT-EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRM 790
Query: 774 QKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVV 830
Q RG L+R KK + R A + +Q +R + K ++ Y+++ +
Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG---------VKNWPWMKLYFKIKPL 841
Query: 831 RRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHA 888
+ + + + + + ++ L ++ R+ E K V + + K +
Sbjct: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE----------KNDL-- 889
Query: 889 IIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVE 948
++ + E L ++ K I +E K+ ++ +++++ + L
Sbjct: 890 ---------QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 940
Query: 949 KLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTRS 1004
K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + +
Sbjct: 941 KKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK 996
Query: 1005 EKKCIEE---HADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM--TETMEKK 1059
EKK ++E A Q E V++L + L+Q+ + L + Q+ K E ++K
Sbjct: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1056
Query: 1060 L---VEETKQLELDLNDERLRYQNLL--NEFSRLEERYDDLKEEMTLMVHVP---KPGHK 1111
L ++ T++ +DL +++L+ + L EF + ++ +++E L + + K
Sbjct: 1057 LEGDLKLTQESIMDLENDKLQLEEKLKKKEFD-INQQNSKIEDEQVLALQLQKKLKENQA 1115
Query: 1112 RTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEP-SEKKVPLDMSLFLKLQKRV 1162
R + E+E +++ E+E+I R EE V ++M+ +KR
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN-----KKRE 1170
Query: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
E ++ ++ +++ + E + K + G +++ +Q+LE E + K EL
Sbjct: 1171 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1230
Query: 1223 NELRKALSE--------KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLV 1274
+++ + + + A YRV +E+ + ++ ++ +L
Sbjct: 1231 DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290
Query: 1275 SQ---KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Q KEA+ + + ++ T +ED+++ + E +A L +S+ D L E
Sbjct: 1291 RQLEEKEALISQLTRGKLS-YTQQMEDLKRQLE--EEGKAKNALAHALQSARHDCDLLRE 1347
Query: 1332 DGELWLVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQN 1388
E E + R+L S++ + +E +A E++ K++ LAQ
Sbjct: 1348 QYE--EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK-------LAQR 1398
Query: 1389 LQLPPEARIEA------SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
LQ EA +EA SL+ RL NE DLM +E+ + L K+ + F K + E
Sbjct: 1399 LQDAEEA-VEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1457
Score = 74.3 bits (181), Expect = 1e-12
Identities = 121/585 (20%), Positives = 244/585 (41%), Gaps = 87/585 (14%)
Query: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTN-------LEGIYN 958
++L+ + + + + + ++ L+R+++E+ K L L + L Y
Sbjct: 1291 RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYE 1350
Query: 959 SETEKLRSDLERLQLSEEEAKVATGRV------LSLQEEIAKLRKDLEQTRSEK------ 1006
ETE +++L+R+ LS+ ++VA R + EE+ + +K L Q +
Sbjct: 1351 EETEA-KAELQRV-LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEA 1408
Query: 1007 ---KC--IEEHADRYKQETEQLVSNLKEENTLLK--QEKEALNHRIVQQAKEMTETMEKK 1059
KC +E+ R + E E L+ +++ N +K+ +I+ + K+ E + +
Sbjct: 1409 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 1468
Query: 1060 LV---EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDST 1116
L +E + L +L + Y+ L + +L+EE++ + G K
Sbjct: 1469 LESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNV--- 1525
Query: 1117 HSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDEL 1176
+E E + E ++ S EE +E + + L+ Q E Q K ++ +L
Sbjct: 1526 ---HELEKVRKQLEVEKLELQSALEE-AEASLEHEEGKILRAQ---LEFNQIKAEIERKL 1578
Query: 1177 DRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPE 1236
K+E++ ++K + L+ E+ R E+ KK++ +LNE+ LS A
Sbjct: 1579 AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSH--ANR 1636
Query: 1237 VTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILL 1296
+ A + L L +LD +A++ DD + ++ ++
Sbjct: 1637 MAAEAQKQVKSLQSLLKDTQIQLD-----------------DAVRANDD---LKENIAIV 1676
Query: 1297 EDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ---L 1353
E + + E+ + +++T RS L EL E E +LL SQ L
Sbjct: 1677 ERRNNLL-QAELEELRAVVEQTERSRKLAEQELIETSE----------RVQLLHSQNTSL 1725
Query: 1354 QSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNL--------QLPPEARIEASLQHEI 1405
+QK+ E++ L+ E++ +E ++ + + +L E A L+
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1785
Query: 1406 TRLTNENLDLMEQLEKQDKTVRK-LKKQLKVFAKKIGELEVGQME 1449
+ DL +L++ ++ K KKQL+ ++ ELE G++E
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE-GELE 1829
Score = 64.3 bits (155), Expect = 1e-09
Identities = 76/350 (21%), Positives = 157/350 (44%), Gaps = 41/350 (11%)
Query: 892 LQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKL- 950
LQ A E ++ KI +E + ++ +E K+ + ++++ ++++ +V+ L
Sbjct: 1542 LQSALEEAEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 951 TNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010
T+L+ S E LR ++++ E ++ + E K K L+ + +
Sbjct: 1601 TSLDAETRSRNEVLRVK-KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1659
Query: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070
+ A R + ++ ++ ++ N LL+ E E L +V+Q + + E++L+E +++++L
Sbjct: 1660 DDAVRANDDLKENIAIVERRNNLLQAELEELR-AVVEQTERSRKLAEQELIETSERVQL- 1717
Query: 1071 LNDERLRYQN--LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSS 1128
L QN L+N+ ++E L+ E+ + ++ E +
Sbjct: 1718 -----LHSQNTSLINQKKKMESDLTQLQSEV----------EEAVQECRNAEEKAKKAIT 1762
Query: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKA 1188
+ A M + E K D S L+ K+ +EQ + +Q LD E+ L+
Sbjct: 1763 DAAMMAE---------ELKKEQDTSAHLERMKK--NMEQTIKDLQHRLDEAEQIALKGGK 1811
Query: 1189 KEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVT 1238
K+ ++ + R ELE ELE+E K+ + +RK SE+ E+T
Sbjct: 1812 KQLQKLEARVRELE------GELEAEQKRNAESVKGMRK--SERRIKELT 1853
Score = 47.4 bits (111), Expect = 1e-04
Identities = 57/311 (18%), Positives = 138/311 (44%), Gaps = 47/311 (15%)
Query: 909 KIEARSVERYKKLHIGMENKIMQLQRKV--DEQNKDYKCLVEKLTNLEGIYNSETEKLRS 966
++ A + ++ K L +++ +QL V ++ K+ +VE+ NL +E E+LR+
Sbjct: 1636 RMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL---LQAELEELRA 1692
Query: 967 DLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSN 1026
+E+ +E K+A ++ E + L ++KK +E + + E E+ V
Sbjct: 1693 VVEQ---TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQE 1749
Query: 1027 LKEENTLLKQEKEALNHRIV--------QQAKEMTETMEKKLVEETKQLELDLND-ERLR 1077
+ ++ K+A+ + Q E M+K + + K L+ L++ E++
Sbjct: 1750 CRNAE---EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1806
Query: 1078 YQNLLNEFSRLEERYDDLKEEMTL--------MVHVPKPGHKRTDSTHSSNESEYIFSSE 1129
+ + +LE R +L+ E+ + + K + + T+ + E +
Sbjct: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK----KN 1862
Query: 1130 IAEMEDIPSRTE----------EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK 1179
+ ++D+ + + E +E++ ++S F K+Q + E E+ + + ++++
Sbjct: 1863 LLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK- 1921
Query: 1180 EEQVLRSKAKE 1190
LR+K+++
Sbjct: 1922 ----LRAKSRD 1928
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 608 bits (1569), Expect = e-173
Identities = 445/1462 (30%), Positives = 729/1462 (49%), Gaps = 135/1462 (9%)
Query: 64 NPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDI 123
NP D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y ++
Sbjct: 81 NPPKFDKIEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEV 139
Query: 124 INAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATV 183
+ AY G+ + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT+
Sbjct: 140 VAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATI 199
Query: 184 SGSAS----------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYR 233
+ + + +E++++ +NP++E+ GNAKT RNDNSSRFGK+I I F +
Sbjct: 200 AVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGK 259
Query: 234 IIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGG 292
+ A++ TYLLEKSRV FQ ER+YHIFYQ+ ++ K +L + N +F + QG
Sbjct: 260 LASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDFPFVSQG- 318
Query: 293 SPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPP 352
+ +DD++E+ T A +LG S ++GI+++ ++H GN+ F + + P
Sbjct: 319 EVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPD 378
Query: 353 KHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLF 412
E LMG++ EM LC ++ E K + Q TN+ ALAK +Y K+F
Sbjct: 379 GTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMF 438
Query: 413 NWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKL 472
W+V +NQ L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F L
Sbjct: 439 LWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVL 498
Query: 473 EQEEYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
EQEEY KE I W IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ H
Sbjct: 499 EQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQH 558
Query: 532 LNKCALFEKPR-LSNKA---FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKM 587
L K F+KP+ KA F + H+A V+Y G+L+KNKD + E + + + S K+
Sbjct: 559 LGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKL 618
Query: 588 LPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLM 647
L LF + A + S S + G+ +TV FR +L+ LM
Sbjct: 619 LSFLFSNYAGAETGDSGGSK---------------KGGKKKGSSFQTVSAVFRENLNKLM 663
Query: 648 ETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFF 707
L +T PH+VRC+ PN+ K P D + QLR GVLE IRI GFPSR Y +F
Sbjct: 664 TNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFK 723
Query: 708 SRYRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRAD 764
RYR+L + D K + +L + +D+++++FG TK+FF+AG + LE++R +
Sbjct: 724 QRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDE 783
Query: 765 KLRAACIRIQKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATII 821
KL Q RG+L+R KK + R + +Q +R + K +
Sbjct: 784 KLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFM---------NVKHWPWM 834
Query: 822 QKYWRMYVVRRRYKIRRAATIVLQSYLR--GFLARNRYRKILREHKAVIIQKRVRGWLAR 879
++++ + + + + + + + R LAR+ R+ E K V + +
Sbjct: 835 NLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQE------- 887
Query: 880 THYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQ 939
K + ++ + E + L E K I +E K+ +L +++E+
Sbjct: 888 ---KNDL-----------QLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEE 933
Query: 940 NKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKL 995
+ LV K NLE + L+ D++ L+L+ E+E +V +L EE+ L
Sbjct: 934 EEMNSELVAKKRNLE----DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989
Query: 996 RKDLEQTRSEKKCIEEHADRY---KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM 1052
+++ + EKK ++E + Q E V+ L + N L+Q+ + L + Q+ K
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049
Query: 1053 T--ETMEKKLVEETKQLE---LDLNDERLRYQNLLN----EFSRLEERYDDLKEEMTLMV 1103
E ++KL + K + +DL +++ + + L E S+L+ + DD +
Sbjct: 1050 ADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQ 1109
Query: 1104 HVPKPGHKRTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEPS-EKKVPLDMSL 1154
K R + E+E+ ++I E+E+I R EE S ++M+
Sbjct: 1110 KKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMN- 1168
Query: 1155 FLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE 1214
+KR E ++ ++ +++ + E + K+ + G +++ +Q+LE E
Sbjct: 1169 ----KKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKE 1224
Query: 1215 NKKLKNELNELR---KALSE-KSAPEVTAPGA----PAYRVLMEQLTSVSEELDVRKEEV 1266
+LK E++++ +ALS+ KS E T + EQ T + +L+++K +
Sbjct: 1225 KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARL 1284
Query: 1267 LILRSQL---VSQKEAI--QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRS 1321
+L V +KE++ Q K +T L+ + + K + A A+ L+ +
Sbjct: 1285 QTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH-ALQSSRHD 1343
Query: 1322 SALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQ 1381
L + E+ E L++A S++ + +E +A E++ K++ ++
Sbjct: 1344 CDLLREQYEEEQE---AKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 1382 QQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQ-------DKTVRKLKKQLK 1434
Q +N + ASL+ RL E DLM LE+ DK R K L
Sbjct: 1401 LQEAEENTETANSKC--ASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLA 1458
Query: 1435 VFAKKI----GELEVGQMENIS 1452
+ +K+ ELE Q E+ S
Sbjct: 1459 EWKQKLDESQAELEAAQKESRS 1480
Score = 85.5 bits (210), Expect = 4e-16
Identities = 134/635 (21%), Positives = 255/635 (40%), Gaps = 112/635 (17%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ K+E + +++A+ ++ + + + KI +LQ +++E +E+ E +
Sbjct: 1084 LKKKEFELSQLQAK-IDDEQVHSLQFQKKIKELQARIEE--------LEEEIEAEHTLRA 1134
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 1135 KIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194
Query: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMT------------- 1053
++ AD + EQ + NL+ L++EK L I A +
Sbjct: 1195 TLRKKQADSVAELGEQ-IDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTC 1253
Query: 1054 ETME------KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102
T+E K E+ QL DLN ++ R Q E S E + L ++T L
Sbjct: 1254 RTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313
Query: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK-- 1160
+ + + + T + N + S + + + + EE E K L +L +
Sbjct: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVA 1373
Query: 1161 ------------RVTELEQEKQVMQDELDRKEEQVLRSKAK----EEERPQIRGA----- 1199
R ELE+ K+ + L EE + +K E+ + +++G
Sbjct: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLM 1433
Query: 1200 -ELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP------------AYR 1246
+LE L+ + + L E ++ L E A A AY
Sbjct: 1434 RDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYE 1493
Query: 1247 VLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTM-----TDSTILLEDVQK 1301
+++QL ++ E +EE+ L Q+ + +Q + + +D + LE+V+
Sbjct: 1494 EVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553
Query: 1302 MKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHE 1361
+ E + L+ + S LD + +D E+ + ++A L+S L ++ RS
Sbjct: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRN 1613
Query: 1362 NEA---EALRGEIQSLKEE---NNRQQ------------QLLAQNLQLPPEARIEASLQH 1403
+ + + G++ ++ + +NRQ QL L L R L+
Sbjct: 1614 DALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673
Query: 1404 EITRLTNENLDLMEQLE------KQDKTVRKLKKQ 1432
++ + N L+E+LE +Q + R+L +Q
Sbjct: 1674 QLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQ 1708
Score = 52.4 bits (124), Expect = 4e-06
Identities = 88/464 (18%), Positives = 205/464 (44%), Gaps = 60/464 (12%)
Query: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965
+KL +E +K + ++ +++ +E + L + NL+ + TE++
Sbjct: 1462 QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIA 1521
Query: 966 SDLERLQLSEEEAKVATGRVLSLQ--------------EEIAKLRKDLEQTRSE--KKCI 1009
+ LQ +E+ K+ LQ +I +++ +L Q +SE +K I
Sbjct: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI 1581
Query: 1010 E--EHADRYKQETEQ--------LVSNLKEENTLLKQEKEA---LNHRIVQ---QAKEMT 1053
E E ++ K+ +++ L + ++ N L+ +K+ LN +Q ++M
Sbjct: 1582 EKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMA 1641
Query: 1054 ETME--KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHK 1111
ET + + + + K +L L+D ++L + + +E R L EE+ M K +
Sbjct: 1642 ETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEM----KVALE 1697
Query: 1112 RTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFL--------------- 1156
+T+ T +E E + +S+ ++ + + ++KK+ D++
Sbjct: 1698 QTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEE 1757
Query: 1157 KLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENK 1216
K +K +T+ + ++ E D K E+ ++ E E L + + + +
Sbjct: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1817
Query: 1217 KLKNELNELRKALS-EKSAPEVTAPGAPAYRVLMEQLTSVSEE--LDVRKEEVLI--LRS 1271
KL+N + EL L E+ GA Y ++++T +EE ++ + + L+ L++
Sbjct: 1818 KLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQA 1877
Query: 1272 QLVSQK-EAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYI 1313
++ S K +A + ++ NT ++ + ++++ ++ +IA++ +
Sbjct: 1878 KVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921
Score = 43.5 bits (101), Expect = 0.002
Identities = 55/267 (20%), Positives = 117/267 (43%), Gaps = 31/267 (11%)
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956
R + EL+++K+ ER ++L E +++ +V + L+ LE
Sbjct: 1681 RNGLLLEELEEMKVALEQTERTRRLS---EQELLDASDRVQLLHSQNTSLINTKKKLEAD 1737
Query: 957 YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAK----------LRKDLEQTRSEK 1006
++ + ++ + +EE+AK A + EE+ K ++K+LEQT +
Sbjct: 1738 IAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1797
Query: 1007 KCIEEHADRY-----KQETEQLVSNLKE-ENTLLKQEKEALNHRIVQQAKEMTETMEKKL 1060
+ + A++ K++ ++L + ++E EN L ++K +A + E+K+
Sbjct: 1798 QHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRG------AEALKGAHKYERKV 1851
Query: 1061 VEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-----TLMVHVPKPGHKRTDS 1115
E T Q E D + LR Q+L+++ + Y EE T + + H+ ++
Sbjct: 1852 KEMTYQAEED-HKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEA 1910
Query: 1116 THSSNESEYIFSSEIAEMEDIPSRTEE 1142
++ +E + A+ D+ S+ E
Sbjct: 1911 AERADIAESQVNKLRAKSRDVGSQKME 1937
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 603 bits (1555), Expect = e-172
Identities = 438/1442 (30%), Positives = 730/1442 (50%), Gaps = 129/1442 (8%)
Query: 64 NPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDI 123
NP D+ L++L+EPAVL+NL+ R+ S +IYTY G+ V +NPY+ LP+Y ++
Sbjct: 81 NPPKFDRIEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPYKWLPVYNPEV 139
Query: 124 INAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATV 183
+ Y G+ + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT+
Sbjct: 140 VEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI 199
Query: 184 SG---------SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRI 234
+ S + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++
Sbjct: 200 AATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKL 259
Query: 235 IGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTK-QGGS 293
A++ TYLLEKSRV FQ + ER+YHIFYQ+ ++ K PE L L + ++Y G
Sbjct: 260 ASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIELLLITTNPYDYPFISQGE 318
Query: 294 PVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPK 353
++ +DDA+E+ T A +LG + + G++++ ++H GN+ F + + P
Sbjct: 319 ILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDG 378
Query: 354 HEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFN 413
E LMG++ ++ LC ++ E K + Q +A +AL+K +Y KLF
Sbjct: 379 TEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFL 438
Query: 414 WIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLE 473
W+V +NQ L + + + FIGVLDI GFE FE NS EQ CIN+ NEKLQQ FN H+F LE
Sbjct: 439 WMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLE 498
Query: 474 QEEYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
QEEY KE I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL
Sbjct: 499 QEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHL 558
Query: 533 NKCALFEKPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKML 588
K F+KP++ + F + H+A V+Y G+LEKNKD + E + + + S ++L
Sbjct: 559 GKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLL 618
Query: 589 PELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLME 648
L+ A T+ SG+ + + KG Q TV FR +L+ LM
Sbjct: 619 AHLY-----ATFATADADSGKKKVAKK-----KGSSFQ-------TVSALFRENLNKLMS 661
Query: 649 TLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFS 708
L T PH+VRCI PN+ K P + + QLR GVLE IRI GFP+R Y +F
Sbjct: 662 NLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQ 721
Query: 709 RYRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADK 765
RYRVL + D K+ C+ +L + +D +Y+FG TK+FF+AG + LE++R D+
Sbjct: 722 RYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDR 781
Query: 766 LRAACIRIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
L R Q RG+L+R ++ +M R++ +Q +R + K ++
Sbjct: 782 LAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFM---------NVKHWPWMK 832
Query: 823 KYWRMYVVRRRYKIRRAATIVLQSY--LRGFLARNRY-RKILREHKAVIIQKRVRGWLAR 879
++++ + + + + + + + + LA++ RK L E ++Q++ L
Sbjct: 833 LFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEK--NDLQL 890
Query: 880 THYKRSMHAIIYLQCCFRRMMAKRELK-KLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938
S + + + C + + AK +L+ K+K E ++++ + K +L+ + E
Sbjct: 891 QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 950
Query: 939 QNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKD 998
KD L L +E ++ K+++ E L +E T +LQE + D
Sbjct: 951 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010
Query: 999 LEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRI---------V 1046
L+ + + + + +Q+ E L S+L++E L L++ K L + +
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
Query: 1047 QQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVP 1106
+ K+ + KK E QL+ + DE+ + L+ R ++L+EE+
Sbjct: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI------- 1123
Query: 1107 KPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP---SEKKVPLDMSLFLKLQKRVT 1163
+ T + S+Y E+E++ R EE + ++ L+ +KR
Sbjct: 1124 -EAERATRAKTEKQRSDY-----ARELEELSERLEEAGGVTSTQIELN-------KKREA 1170
Query: 1164 ELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELN 1223
E + ++ +++ + E V + K + G +++ +Q+LE E + K E++
Sbjct: 1171 EFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID 1230
Query: 1224 ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV---SEELDVRKEEVLILRSQL------- 1273
+L ++ +S + A R L +QL+ +EE+ E+ +S+L
Sbjct: 1231 DLSSSM--ESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 1288
Query: 1274 ---VSQKEAI--QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSAL--DY 1326
+ +KE+I Q K T T L+ + ++K + A A+ L+ + L +
Sbjct: 1289 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH-ALQSSRHDCDLLREQ 1347
Query: 1327 HELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLA 1386
+E ++G+ L L +AN S++ + +E +A E++ K++ LA
Sbjct: 1348 YEEEQEGKAEL-QRALSKAN----SEVAQWRTKYETDAIQRTEELEEAKKK-------LA 1395
Query: 1387 QNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
Q LQ E ++E ASL+ RL E DLM +E+ + L K+ + F K +
Sbjct: 1396 QRLQ-DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVL 1454
Query: 1441 GE 1442
E
Sbjct: 1455 AE 1456
Score = 78.2 bits (191), Expect = 7e-14
Identities = 137/624 (21%), Positives = 264/624 (42%), Gaps = 84/624 (13%)
Query: 915 VERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKL---RSDLERL 971
++ +++ +E + + + ++D+ + + + + NLE I + ++L R E +
Sbjct: 1208 IDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267
Query: 972 QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEEN 1031
Q S E R LQ E +L + LE+ S + + Q+TE+L L+EEN
Sbjct: 1268 QRSLSELTTQKSR---LQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 1324
Query: 1032 -----------------TLLKQEKE--------------ALNHRIVQ-QAKEMTETMEK- 1058
LL+++ E N + Q + K T+ +++
Sbjct: 1325 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1384
Query: 1059 -KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKPGHKRTDST 1116
+L E K+L L D + + + + + LE+ L+ E+ LMV V +R +S
Sbjct: 1385 EELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-----ERANSL 1439
Query: 1117 HSS-NESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDE 1175
++ ++ + F +AE + + E + L+ SL + + TEL + K ++
Sbjct: 1440 AAALDKKQRNFDKVLAEWK------TKCEESQAELEASL-KESRSLSTELFKLKNAYEEA 1492
Query: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235
LD+ E +K E+E + ++ ELE K+++ E +++ AL E A
Sbjct: 1493 LDQLETVKRENKNLEQEIADLT-EQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA- 1550
Query: 1236 EVTAPGAPAYRVLMEQLTSVSEELD----VRKEEVLILRSQLVSQKEAIQPKDDKNTMTD 1291
+ A R+ +E LT V E+D + EE+ L+ E +Q D +
Sbjct: 1551 ALEHEEAKILRIQLE-LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 1609
Query: 1292 STILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE-DGELWLVYEGLKQANRLLE 1350
+ + K K +G++ + I L NR +A L G+L L A R E
Sbjct: 1610 NEAIR---LKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 1666
Query: 1351 SQLQSQKRSHENEAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITR 1407
L+ Q E A L+ E++ L+ E+ R ++L Q L L R++
Sbjct: 1667 -DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL-LDSNERVQL-------- 1716
Query: 1408 LTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIP 1467
L +N L+ +K + + +L+ +++ ++ E + I+ ++ E +
Sbjct: 1717 LHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEEL------ 1770
Query: 1468 RKEKDFQGMLEYKKEDEQKLVKNL 1491
+KE+D LE K++ ++ VK+L
Sbjct: 1771 KKEQDTSAHLERMKKNLEQTVKDL 1794
Score = 63.5 bits (153), Expect = 2e-09
Identities = 113/501 (22%), Positives = 221/501 (44%), Gaps = 94/501 (18%)
Query: 901 AKRELKKLKIEARSVE-RYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLT-----NLE 954
++ EL+ E+RS+ KL E + QL+ V +NK+ + + LT N +
Sbjct: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLET-VKRENKNLEQEIADLTEQIAENGK 1522
Query: 955 GIYNSETEKLRSDLER--LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEK-K 1007
I+ E + + +LE+ +QL+ EEA+ A ++L +Q E+ +++ ++++ +EK +
Sbjct: 1523 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582
Query: 1008 CIEEHADRYKQETEQLVSNL------KEENTLLKQEKEA-LNHRIVQQA---KEMTETME 1057
IE+ Y++ E + S L + E LK++ E LN +Q + ++ ET++
Sbjct: 1583 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLK 1642
Query: 1058 --KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK---EEMTLMVHVPKPGHK- 1111
+ + + K +L L+D ++L + + +E R + L+ EE+ + + K
Sbjct: 1643 HLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKL 1702
Query: 1112 ------------------RTDSTHSSNESEYIFSSEIAEMEDIP--SRTEEPSEKKVPLD 1151
T H+ + E +E+ED +R E KK D
Sbjct: 1703 AEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 1762
Query: 1152 MSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
++ + L++ LEQ + +Q LD E+ L+ K+ ++ + R E
Sbjct: 1763 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1822
Query: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE-- 1258
LE+ ELE E KK + LRK Y +++LT SEE
Sbjct: 1823 LEF------ELEGEQKKNTESVKGLRK-----------------YERRVKELTYQSEEDR 1859
Query: 1259 LDVRKEEVLI--LRSQLVSQKEAIQPKDDKNT--MTDSTILLEDVQKMKDKGEIAQAYIG 1314
+V + + L+ L+ ++ S K + D++ +T ++++ +++ +IA++ +
Sbjct: 1860 KNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVN 1919
Query: 1315 -LKETNR---SSALDYHELNE 1331
L+ R SS + HE E
Sbjct: 1920 KLRAKTRDFTSSRMVVHESEE 1940
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 601 bits (1550), Expect = e-171
Identities = 456/1502 (30%), Positives = 748/1502 (49%), Gaps = 155/1502 (10%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
V++PD ++ + A+++ + G KV E GK + D ++ NP
Sbjct: 37 VFVPDDKQEFVKAKIVS--REGGKVTA-ETEYGKTVTVKEDQVMQQ-----NPPKFDKIE 88
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L++LHEPAVL+NL+ R+ S +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 89 DMAMLTFLHEPAVLYNLKDRY-GSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG------- 185
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFA ++
Sbjct: 148 SEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKK 207
Query: 186 --SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
S + +E++++ +NP +E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 208 DQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
Query: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDA 302
LEKSRV+FQ + ER+YHIFYQ+ ++ K ML + N ++ + QG + V +DDA
Sbjct: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVAS-IDDA 326
Query: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
+E+ T A +LG + + ++++ I+H GN+ F + + P E
Sbjct: 327 EELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAY 386
Query: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
LMG++ ++ LCH ++ E K + Q A ALAK +Y ++FNW+V +N
Sbjct: 387 LMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINAT 446
Query: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
L + + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 447 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 506
Query: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
WT IDF D Q CI+LIE +GI+ +L+EEC PK TD T+ KL++ HL K A F+KP
Sbjct: 507 EWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
Query: 542 R-LSNKA---FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
R + K F + H+A V+Y G+L+KNKD + E + + + S K+L LF +
Sbjct: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFAN--- 623
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
+ P+ + K KG Q TV R +L+ LM L +T PH+
Sbjct: 624 -------YAGADAPIEKGKGKAKKGSSFQ-------TVSALHRENLNKLMTNLRSTHPHF 669
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK-- 715
VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F RYR+L
Sbjct: 670 VRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAA 729
Query: 716 -QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQ 774
+ D ++ + +L L +D ++Y+FG TK+FF+AG + LE++R ++L RIQ
Sbjct: 730 IPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQ 789
Query: 775 KTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVR 831
RG L R KK L R + + +Q +R + K ++ Y+++ +
Sbjct: 790 AQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMG---------VKNWPWMKLYFKIKPLL 840
Query: 832 RRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAI 889
+ + + + + + L+ L ++ R+ E K V + + K +
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQE----------KNDL--- 887
Query: 890 IYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEK 949
++ + E L ++ K I +E K+ ++ +++++ + L K
Sbjct: 888 --------QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK 939
Query: 950 LTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
LE E +L+ D++ L+L+ E+E +V +L EE+A L + + + E
Sbjct: 940 KRKLE----DECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
Query: 1006 KKCIEE---HADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM--TETMEKKL 1060
KK ++E A Q E V+ L + L+Q+ + L + Q+ K E ++KL
Sbjct: 996 KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1055
Query: 1061 ---VEETKQLELDLN------DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHK 1111
++ T++ +DL DERL+ ++ E + L R +D + + + K
Sbjct: 1056 EGDLKLTQESIMDLENDKQQLDERLKKKDF--ELNALNARIEDEQALGSQLQKKLKELQA 1113
Query: 1112 RTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEP-SEKKVPLDMSLFLKLQKRV 1162
R + E+E +++ E+E+I R EE V ++M+ +KR
Sbjct: 1114 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN-----KKRE 1168
Query: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
E ++ ++ +++ + E + K + G +++ +Q+LE E + K EL
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQ---------- 1272
+++ + + + A R L +Q+ + + + V L SQ
Sbjct: 1229 DDVTSNMEQ--IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGE 1286
Query: 1273 ---LVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHEL 1329
+ +KEA+ + + +T T LED+++ + E +A L +S+ D L
Sbjct: 1287 LSRQLDEKEALISQLTRGKLT-YTQQLEDLKRQLE--EEVKAKNALAHALQSARHDCDLL 1343
Query: 1330 NEDGELWLVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLA 1386
E E E + R+L S++ + +E +A E++ K++ LA
Sbjct: 1344 REQYE--EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK-------LA 1394
Query: 1387 QNLQLPPEARIEA------SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
Q LQ EA +EA SL+ RL NE DLM +E+ + L K+ + F K +
Sbjct: 1395 QRLQEAEEA-VEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 1453
Query: 1441 GE 1442
E
Sbjct: 1454 AE 1455
Score = 75.1 bits (183), Expect = 6e-13
Identities = 132/643 (20%), Positives = 261/643 (40%), Gaps = 114/643 (17%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ K++ + + AR +E + L ++ K+ +LQ +++E +E+ E +
Sbjct: 1080 LKKKDFELNALNAR-IEDEQALGSQLQKKLKELQARIEE--------LEEELEAERTARA 1130
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EKLRSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
Query: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKEAL---------NHRIVQQAK----EMT 1053
++HAD + EQ + NL+ L++EK N + +AK +M
Sbjct: 1191 ALRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMC 1249
Query: 1054 ETMEKKL------VEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-----KEEMTLM 1102
T+E ++ EET++ DL +R + Q E SR + + L + ++T
Sbjct: 1250 RTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYT 1309
Query: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRV 1162
+ + + + N + S + + + + EE +E K L L K
Sbjct: 1310 QQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVL----SKAN 1365
Query: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
+E+ Q + + + ++ E++ +K K +R Q +E + K LE +L+NE+
Sbjct: 1366 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI 1425
Query: 1223 NELRKALSEKSAP------------EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILR 1270
+L + +A ++ A Y +L S +E E+ L+
Sbjct: 1426 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLK 1485
Query: 1271 SQLVSQKEAIQP--KDDKNTMTDSTILLE-------------------DVQKMKDKGEIA 1309
+ E ++ +++KN + + L E + +KM+ + +
Sbjct: 1486 NAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 1310 QAYIGLKETNRS---SALDYHELNEDGELWLVY--EGLKQANR-------LLESQLQSQK 1357
+A L+ + L+++++ + E L E ++QA R L++ L ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAET 1605
Query: 1358 RSHE-------------NEAE-----ALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEA 1399
RS NE E A R ++ K+ + Q L +QL R
Sbjct: 1606 RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAND 1665
Query: 1400 SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
L+ I + N L +LE+ V + ++ K+ +++ E
Sbjct: 1666 DLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Score = 55.8 bits (133), Expect = 4e-07
Identities = 100/527 (18%), Positives = 215/527 (40%), Gaps = 95/527 (18%)
Query: 918 YKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE 977
+ K+ + K + Q +++ K+ + L +L L+ Y E L + + +EE
Sbjct: 1449 FDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEE 1508
Query: 978 AKVATGRVLSLQE---EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLL 1034
T ++ S + E+ K+RK LE + E + E A+ + E + + E +
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 1035 KQEKEALNHRIVQQAKEMTETMEKKL-VEETKQLELDLNDERLRYQNLLNEFSRLEERYD 1093
K E E ++ ++ +EM + L V ++ Q LD + R R NE R++++ +
Sbjct: 1569 KAEIE---RKLAEKDEEMEQAKRNHLRVVDSLQTSLDA-ETRSR-----NEALRVKKKME 1619
Query: 1094 DLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMS 1153
EM + + +H+ +R ++K+V
Sbjct: 1620 GDLNEMEIQL------------SHA-------------------NRMAAEAQKQV----- 1643
Query: 1154 LFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELES 1213
K + L ++ Q+ D+ R + + + A E R + AELE ++ E
Sbjct: 1644 ------KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
Query: 1214 ENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL 1273
K + EL E + + ++L Q TS+ + ++ L++++
Sbjct: 1698 SRKLAEQELIETSERV----------------QLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 1274 VSQKEAIQ-----PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHE 1328
+EA+Q + K +TD+ ++ E+++K +D + +K+ + D
Sbjct: 1742 ---EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKNMEQTIKDLQH 1795
Query: 1329 LNEDGELWLVYEGLKQANRL------LESQLQSQKRSHENEAEALRGEIQSLKE-----E 1377
++ E + G KQ +L LE++L+++++ + + +R + +KE E
Sbjct: 1796 RLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTE 1855
Query: 1378 NNRQQQLLAQNLQLPPEARIEASLQ--HEITRLTNENLDLMEQLEKQ 1422
+R+ L Q+L + +++A + E N NL +++ +
Sbjct: 1856 EDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 597 bits (1539), Expect = e-170
Identities = 464/1530 (30%), Positives = 728/1530 (47%), Gaps = 200/1530 (13%)
Query: 12 RVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNP--DILV 69
RVW+PD ++ + AE+ K G +V + E KD + L + EL + P D+L
Sbjct: 76 RVWVPDEQDAYVEAEV-KSEATGGRVTV----ETKDQKV-LMVREAELQPMNPPRFDLL- 128
Query: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129
D+ +++L+E +VLHNLR R+ +IYTY G+ V INPY+ LP+Y ++ AY G
Sbjct: 129 --EDMAMMTHLNEASVLHNLRQRYA-RWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKG 185
Query: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG---- 185
+ D PHI+AVA+ AY M R+ NQS++++GESGAGKTV+ K ++YFA V+
Sbjct: 186 KRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG 245
Query: 186 ---------SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIG 236
+ + +E++++ +NP ME+ GNAKT RNDNSSRFGK+I I F ++
Sbjct: 246 PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLAS 305
Query: 237 ANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPV 295
A++ +YLLEKSRV+FQ ER+YH++YQ+ + K ML L N ++++ QG V
Sbjct: 306 ADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITV 365
Query: 296 IEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHE 355
+ ++D +E+ T A +LG S + ++I+ +LH GN+ F + + E
Sbjct: 366 -DNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTE 424
Query: 356 PLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWI 415
LMGV ++ L H ++ E K S Q A ALAK Y +LF W+
Sbjct: 425 SADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWL 484
Query: 416 VDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
V +NQ L + + + FIGVLDI GFE FE NSFEQ CIN+ NEKLQQ FN H+F LEQE
Sbjct: 485 VSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQE 544
Query: 476 EYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNK 534
EY +E I W IDF D QPCI+LIE LGIL +L+EEC PK +D ++ KLY+ H K
Sbjct: 545 EYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHAGK 604
Query: 535 CALFEKPRLSNKA-----FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
F++PR K F + H+A V Y G+LEKNKD + E + + + S+ ++L
Sbjct: 605 SPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLA 664
Query: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649
L+++ + S T P K + + A +TV + +L+ LM
Sbjct: 665 TLYENYAGSCS------------TEPPKSGVKEKRKKAAS--FQTVSQLHKENLNKLMTN 710
Query: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709
L AT PH+VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F R
Sbjct: 711 LRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQR 770
Query: 710 YRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKL 766
YR+L D D ++ + +L L LD +YQFG TK+FF+AG + LE+LR +L
Sbjct: 771 YRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRL 830
Query: 767 RAACIRIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQK 823
+Q RG L+R +Y R+ R A T+Q +R + A K + ++
Sbjct: 831 AKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNA---------VKNWSWMKL 881
Query: 824 YWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYK 883
+++M + R + L++ LRG +RG LA K
Sbjct: 882 FFKMKPLLRSAQAEEELA-ALRAELRG----------------------LRGALAAAEAK 918
Query: 884 R----SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQ 939
R H I + + + E L K + +E K+ +L +++++
Sbjct: 919 RQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDE 978
Query: 940 NKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQL----SEEEAKVATGRVLSLQEEIAKL 995
+ L + LE E +L+ D++ L+L +E+E + +V +L EE+A L
Sbjct: 979 EEVNADLAARRRKLE----DECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAAL 1034
Query: 996 RKDLEQTRSEKKCIEEHAD---------------------RYKQETEQLVSNLKEENTLL 1034
+ + + EKK ++E R +Q+ E L +L++E L
Sbjct: 1035 DESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLR 1094
Query: 1035 KQEKEA---------LNHRIVQQAKEMTETMEKKLVE---ETKQLELDLNDERLRYQNLL 1082
+ A L V A + + +E+KL + E QL L + DE+L +
Sbjct: 1095 MDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQ 1154
Query: 1083 NEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEE 1142
+ L+ R ++L+EE+ + R + + E+E++ R EE
Sbjct: 1155 KKIKELQARAEELEEEL----EAERAARARVEKQR---------AEAARELEELSERLEE 1201
Query: 1143 PSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELE 1202
+KR EL + ++ +++ R E V + K+ E G +++
Sbjct: 1202 AGGASAGQREG----CRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVD 1257
Query: 1203 YESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVR 1262
RQ+LE E +L+ E+++L A + ++ A R +QL+ E ++
Sbjct: 1258 SLQRVRQKLEKEKSELRMEVDDL--AANVETLTRAKASAEKLCRTYEDQLS----EAKIK 1311
Query: 1263 KEEVLILRSQLVSQKEAIQPKDDK--NTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNR 1320
EE+ + +Q+ +Q + + + + L+ + + K A A L+E R
Sbjct: 1312 VEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGK-----ALAAQSLEELRR 1366
Query: 1321 SSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSL------ 1374
+L E+ + L A + L + HE EAEA + E+Q L
Sbjct: 1367 -------QLEEESK---AKSALAHAVQALRHDCDLLREQHEEEAEA-QAELQRLLSKANA 1415
Query: 1375 ----------------KEENNRQQQLLAQNLQLPPEARIEA------SLQHEITRLTNEN 1412
EE ++ LA LQ E +EA SL+ RL E+
Sbjct: 1416 EVAQWRSKYEADAIQRTEELEEAKKKLALRLQ-EAEEGVEAANAKCSSLEKAKLRLQTES 1474
Query: 1413 LDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
D+ +LE+ L K+ + + + E
Sbjct: 1475 EDVTLELERATSAAAALDKKQRHLERALEE 1504
Score = 76.3 bits (186), Expect = 3e-13
Identities = 126/577 (21%), Positives = 240/577 (41%), Gaps = 88/577 (15%)
Query: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVD---EQNKDYKCLVEKLTNLE 954
+ +A + L++L+ R +E K + + + L+ D EQ+++ +L L
Sbjct: 1354 KALAAQSLEELR---RQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLL 1410
Query: 955 GIYNSETEKLRSDLER--LQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
N+E + RS E +Q +EE + L LQE + +E ++ +E+
Sbjct: 1411 SKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEA----EEGVEAANAKCSSLEKA 1466
Query: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNH--RIVQQAKEMTETMEKKLVEETKQLELD 1070
R + E+E + L+ + + H R +++ + E M+++L E ++
Sbjct: 1467 KLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQREL-EAAQRESRG 1525
Query: 1071 LNDE--RLRY---------QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSS 1119
L E RLR+ + L E L+E DL ++++L S S
Sbjct: 1526 LGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSL-------------SGKSI 1572
Query: 1120 NESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK 1179
E E + E +I + EE +E + L+ + L++Q EL Q K + +L K
Sbjct: 1573 QELEKTKKALEGEKSEIQAALEE-AEGALELEETKTLRIQ---LELSQVKAEVDRKLAEK 1628
Query: 1180 EEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239
+E+ + + + A L+ E+ R E KK++ +LN+L L + A
Sbjct: 1629 DEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688
Query: 1240 PGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDV 1299
A R++ QL +E ++E L ++L Q +A++ + +++L ++
Sbjct: 1689 QAAT--RLMQAQL----KEEQAGRDEEQRLAAELHEQAQALERR--------ASLLAAEL 1734
Query: 1300 QKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ---LQSQ 1356
++++ L++ RS L EL E E LL SQ L +Q
Sbjct: 1735 EELR---------AALEQGERSRRLAEQELLEATE----------RLNLLHSQNTGLLNQ 1775
Query: 1357 KRSHENEAEALRGEIQSLKEENNRQQQLLAQNL--------QLPPEARIEASLQHEITRL 1408
K+ E + L GE++ +E ++ + + +L E A L+ L
Sbjct: 1776 KKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTL 1835
Query: 1409 TNENLDLMEQLEKQDK-TVRKLKKQLKVFAKKIGELE 1444
+L +LE+ ++ +R KKQ++ K+ ELE
Sbjct: 1836 EQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELE 1872
Score = 54.3 bits (129), Expect = 1e-06
Identities = 70/329 (21%), Positives = 149/329 (45%), Gaps = 28/329 (8%)
Query: 1119 SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDR 1178
S ++E ++ AE+ + K+ L+ + + + + +L + Q QD L
Sbjct: 891 SAQAEEELAALRAELRGLRGALAAAEAKRQELEET-HVSITQEKNDLALQLQAEQDNLAD 949
Query: 1179 KEEQ---VLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235
EE+ +++SK + E + + LE E +L + +KL++E EL+K + +
Sbjct: 950 AEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKL- 1008
Query: 1236 EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTIL 1295
A + ++ +++EE+ E V ++L +K+A+Q +
Sbjct: 1009 -TLAKAEKEKQATENKVKNLTEEMAALDESV----ARLTKEKKALQEAHQQ--------A 1055
Query: 1296 LEDVQKMKDK-GEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQ 1354
L D+Q +D+ + +A + L++ L ++ +L + E +A R LE L
Sbjct: 1056 LGDLQAEEDRVSALTKAKLRLEQQVEDLECS---LEQEKKLRMDTE---RAKRKLEGDL- 1108
Query: 1355 SQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLD 1414
K + E+ A+A + + Q ++ + +L +L++ E + A +Q +I L +
Sbjct: 1109 --KLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE 1166
Query: 1415 LMEQLEKQDKTVRKLKKQLKVFAKKIGEL 1443
L E+LE + +++KQ A+++ EL
Sbjct: 1167 LEEELEAERAARARVEKQRAEAARELEEL 1195
Score = 52.8 bits (125), Expect = 3e-06
Identities = 78/335 (23%), Positives = 143/335 (42%), Gaps = 61/335 (18%)
Query: 912 ARSVERYKKLHIGMENKIMQLQRKVDEQ--NKDYKCLVEKLTNLEGIYNSETEKLRSDLE 969
A +E K L I +E + Q++ +VD + KD +C NL + E L++ L+
Sbjct: 1599 ALELEETKTLRIQLE--LSQVKAEVDRKLAEKDEEC-----ANLRRNHQRAVESLQASLD 1651
Query: 970 RLQLSEEEA----KVATGRVLSLQEEIAKLRKDLEQTRSEKKCI-----EEHADRYKQET 1020
+ EA K G + L+ ++ + + ++ + + EE A R E
Sbjct: 1652 AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGR--DEE 1709
Query: 1021 EQLVSNLKEENTLLKQEKEALNHRI------VQQAKEMTETMEKKLVEETKQLELDLNDE 1074
++L + L E+ L++ L + ++Q + E++L+E T++L L
Sbjct: 1710 QRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNL----- 1764
Query: 1075 RLRYQN--LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAE 1132
L QN LLN+ +LE L E V + +R ++ + ++
Sbjct: 1765 -LHSQNTGLLNQKKKLEADLAQLSGE------VEEAAQERREAEEKAKKA---------- 1807
Query: 1133 MEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEE 1192
+ D EE +++ D S L+ K+ LEQ + +Q L+ E+ LR K+ +
Sbjct: 1808 ITDAAMMAEELKKEQ---DTSAHLERMKKT--LEQTVRELQARLEEAEQAALRGGKKQVQ 1862
Query: 1193 RPQIRGAELEYESLKRQELESENKKLKNELNELRK 1227
+ + + ELE EL++E KK L +RK
Sbjct: 1863 KLEAKVRELE------AELDAEQKKHAEALKGVRK 1891
Score = 42.0 bits (97), Expect = 0.006
Identities = 69/345 (20%), Positives = 137/345 (39%), Gaps = 30/345 (8%)
Query: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967
L E R+ +L ME + L+ ++ + + T L E + R +
Sbjct: 1650 LDAETRARNEALRLKKKMEGDLNDLELQLGHATRQ-ATEAQAATRLMQAQLKEEQAGRDE 1708
Query: 968 LERLQLS-EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSN 1026
+RL E+A+ R L E+ +LR LEQ ++ E+ E + ++
Sbjct: 1709 EQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQEL----LEATERLNL 1764
Query: 1027 LKEENTLLKQEKEALNHRIVQQAKEMTETMEKK--LVEETKQLELD---LNDERLRYQNL 1081
L +NT L +K+ L + Q + E+ E +++ E+ K+ D + +E + Q+
Sbjct: 1765 LHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDT 1824
Query: 1082 LNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTE 1141
R+++ + E+ + + R + +++ E+E
Sbjct: 1825 SAHLERMKKTLEQTVRELQARLEEAEQAALR-----GGKKQVQKLEAKVRELE----AEL 1875
Query: 1142 EPSEKKVPLDMSLFLKLQKRVTEL-----EQEKQV--MQDELDRKEEQVLRSKAKEEERP 1194
+ +KK + K ++RV EL E K + MQD +D+ + +V K + EE
Sbjct: 1876 DAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAE 1935
Query: 1195 QIRGAELEYESLKRQELESENKK---LKNELNELRKALSEKSAPE 1236
Q L + EL+ ++ + + N+LR + P+
Sbjct: 1936 QQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDALGPK 1980
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 596 bits (1536), Expect = e-170
Identities = 464/1487 (31%), Positives = 745/1487 (50%), Gaps = 120/1487 (8%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P ++ +++A + ++ GD+V++ +E GK + D K NP
Sbjct: 36 VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V +NPY+ LPIY E I++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
+M PHI+A+A+ AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 187 -ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
+ +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE
Sbjct: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305
KSR + QA +ER +HIFY + A AK L L +N+ + G P+ DD +
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDD-EMF 326
Query: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364
T +A ++G SE Q+ I ++++ +L LGN+ F R+ D ++P + C LM
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV-CHLM 385
Query: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
G++ + + ++ + K +K QA A +ALAK Y +LF WI+ VN+AL
Sbjct: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
Query: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483
+Q SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
Query: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
W IDF D QPCI LIE + G+L LLDEEC PK TD ++ +KL T F+
Sbjct: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQGSHPKFQ 564
Query: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
KP+ L +K F I H+A KV+Y +L KN D + + +L +S K + +L++D ++
Sbjct: 565 KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
+ + L + +K KG +TVG ++ L LM TL TTP++
Sbjct: 625 IVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTLRNTTPNF 675
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
VRCI PN K D ++QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
Query: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
D KQ C +++ L LD + Y+ G++KIFFR G +A+LE+ R K+ + Q
Sbjct: 736 IPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 795
Query: 776 TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY------- 828
RG+L RK + + R+ +T + + Q C A R ++WR++
Sbjct: 796 MCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLFTKVKPLL 845
Query: 829 -VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
V R+ +++ + ++ R A N +++ ++H + +K + + +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 888 AIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRKVDEQNKD 942
A + R K+EL+++ ++EAR E R ++L K+ Q ++EQ ++
Sbjct: 906 A---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLDLEEQLEE 961
Query: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQT 1002
+ +KL + ++ +KL ++ L + ++ K++ R L L+E I+ L +L +
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDLTTNLAEE 1018
Query: 1003 RSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETM------ 1056
+ K + + ++++ +L LK+E +QE E L ++ A + E +
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
Query: 1057 --EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG 1109
E K+ K+ EL L+DE + N L + LE DL+E++
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
Query: 1110 HKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
K+ + E E S + E R +E + K LD + +V E
Sbjct: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQE 1196
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQELESENK 1216
+ Q+ +EL + EQ R+KA E+E + G EL +QE+E + K
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQEVEHKKK 1255
Query: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQ 1276
KL+ ++ EL+ S+ A L ++ SV+ L+ + + + L + S
Sbjct: 1256 KLEAQVQELQSKCSD--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 1277 KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELW 1336
+Q T + E QK+ ++ Q E R+S D +L+E+ E
Sbjct: 1314 SSQLQD-------TQELLQEETRQKLNVSTKLRQL-----EEERNSLQD--QLDEEME-- 1357
Query: 1337 LVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQNLQLPPEA 1395
+ L++ L QL K+ ++ A +++L+E R Q+++ Q +A
Sbjct: 1358 -AKQNLERHISTLNIQLSDSKKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKA 1412
Query: 1396 RIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
L+ RL E DL+ L+ Q + V L+K+ + F + + E
Sbjct: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Score = 91.7 bits (226), Expect = 6e-18
Identities = 144/668 (21%), Positives = 271/668 (40%), Gaps = 92/668 (13%)
Query: 901 AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940
AK+E+ KK K+EA+ E K G + +K+ +LQ +V+
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 941 --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985
KD L +L + + + ET +KL + QL EE EAK R
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 986 LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
+S L +++ +K L+ S + +EE R+++E E L EE + E +R
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1424
Query: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
+ Q+ ++ ++ + +QL +L ++ ++ LL E + +Y D ++
Sbjct: 1425 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159
+ ++ + E E AEMED+ S ++ + L+ S L+
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1538
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198
++ E++ + + ++DEL E+ LR + EE+R Q++
Sbjct: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
Query: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
ELE E +R + KKL+ +L +L L SA + R L Q+
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1656
Query: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311
EL D R I + ++K+A + D + + E +K D K E+A+
Sbjct: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
Query: 1312 YIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEI 1371
+ +AL + + + + E L++ +E+ + + R +AE L E+
Sbjct: 1717 LAS--SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVRKATQQAEQLSNEL 1773
Query: 1372 ----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQ 1422
+ ++ + +QQL QN +L E +++ + I L + L EQ+E++
Sbjct: 1774 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1833
Query: 1423 DKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1482
+ + K LK KK+ E+ + + + E N + K + LE +E
Sbjct: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEE 1891
Query: 1483 DEQKLVKN 1490
+ Q++ N
Sbjct: 1892 ESQRINAN 1899
Score = 74.7 bits (182), Expect = 8e-13
Identities = 122/587 (20%), Positives = 246/587 (41%), Gaps = 61/587 (10%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
M ++ + ++ +E++K+ ++ ++ ++++N D + L +
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
+ +KL + ++ LQ + + A L +++ KL+ ++E E A + ++
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
L S L++ LL++E ++ LN T ++L EE L+ L++E
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
QNL S L + D K+++ V + G KR + +Y E A D
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1416
Query: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
+T+ ++++ D+ + L Q+++ ++KQ D+L +E+ + A E +R +
Sbjct: 1417 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
Query: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA------------PGAP 1243
E E ++L E + K EL K L + V++
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
Query: 1244 AYRVLMEQLTSVSEEL--DVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTI- 1294
A ME++ + EEL +++ E LR ++ Q + +Q +D++N +
Sbjct: 1536 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595
Query: 1295 --LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ 1352
L E +++D+ + K+ D EL D + E +KQ R L++Q
Sbjct: 1596 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQL-RKLQAQ 1653
Query: 1353 LQSQKRSHENEAEALRGEIQSLKEENNRQQQ-------LLAQNLQLPPEARIEASLQHEI 1405
++ +R E +A A R EI + +EN ++ + L ++L AR +A L+ E
Sbjct: 1654 MKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE- 1711
Query: 1406 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENIS 1452
L E + R+L+ ++ +++ E E G ME +S
Sbjct: 1712 -ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE-EQGNMEAMS 1756
Score = 68.9 bits (167), Expect = 4e-11
Identities = 96/464 (20%), Positives = 191/464 (41%), Gaps = 56/464 (12%)
Query: 989 QEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQ 1048
QEE + ++D Q E+ ++ A+ +E EQ S L EE LL+++ +A + +
Sbjct: 850 QEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELYAE 905
Query: 1049 AKEMTETMEKK---LVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105
A+EM + K L E ++E L +E R Q L E ++ ++ DL+E++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL------ 959
Query: 1106 PKPGHKRTDSTHSSNESEYIFS-SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
+ ++ + E + + ++I ++ED ++ + K L ++ T
Sbjct: 960 -----EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
L +E++ K + + + K K E L+ E RQELE +KL+ + ++
Sbjct: 1015 LAEEEE--------KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1066
Query: 1225 LRKALSEKSAP--EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282
+ +++ A E+ A L L + +E+ +K L +L +Q
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-AQKNNALKKIRELEGHISDLQE 1125
Query: 1283 KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN--EDGELWLVYE 1340
D + + ++ +D GE +A E S EL + E+ ++ +
Sbjct: 1126 DLDSERAARN----KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1181
Query: 1341 GLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1400
L + R E+Q+Q ++ H E L +++ K R +A+
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK--------------------RAKAN 1221
Query: 1401 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
L L EN DL +L + ++++ + K ++ EL+
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Score = 67.0 bits (162), Expect = 2e-10
Identities = 92/385 (23%), Positives = 162/385 (42%), Gaps = 53/385 (13%)
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHI-GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955
+R +A KKL+ + + +E I G E I QL RK+ Q KD++ LE
Sbjct: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQ------RELED 1663
Query: 956 IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR 1015
S E + E +E++AK ++ LQE++A + +Q EK
Sbjct: 1664 ARASRDEIFATAKE----NEKKAKSLEADLMQLQEDLAAAERARKQADLEK--------- 1710
Query: 1016 YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------KKLVEETKQ 1066
++ E+L S+L N L+ EK L RI Q +E+ E ME +K ++ +Q
Sbjct: 1711 -EELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 1067 LELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIF 1126
L +L ER Q + +LE + +L+ ++ M K K T +
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA---------L 1819
Query: 1127 SSEIAEMEDIPSRTEEPSEKKVPLDMSL---FLKLQKRVTELEQEKQVMQDELDRKE--- 1180
++IA++E+ + E+ + +K SL KL++ + ++E E+++ + ++ E
Sbjct: 1820 EAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 1181 ---EQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEV 1237
+Q+ R + EE Q A + E N+ + E+N L+ L +
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSF 1936
Query: 1238 TAPGAPAYRVLMEQLTSVSEELDVR 1262
R ++E EE D R
Sbjct: 1937 VPSRRSGGRRVIENADGSEEETDTR 1961
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%)
Query: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Q+ Q+E +Q K+D ++QK K++ + A+ NE
Sbjct: 846 QVTRQEEEMQAKED------------ELQKTKERQQKAE-------------------NE 874
Query: 1332 DGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1391
EL + L + LL+ QLQ++ + EAE +R + + K+E ++ L +L
Sbjct: 875 LKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMRVRLAAKKQE--LEEILHEMEARL 931
Query: 1392 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
E LQ E ++ + LDL EQLE+++ +KL+ + KI +LE
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 596 bits (1536), Expect = e-170
Identities = 464/1487 (31%), Positives = 745/1487 (50%), Gaps = 120/1487 (8%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P ++ +++A + ++ GD+V++ +E GK + D K NP
Sbjct: 36 VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V +NPY+ LPIY E I++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
+M PHI+A+A+ AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 187 -ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
+ +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE
Sbjct: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305
KSR + QA +ER +HIFY + A AK L L +N+ + G P+ DD +
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDD-EMF 326
Query: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364
T +A ++G SE Q+ I ++++ +L LGN+ F R+ D ++P + C LM
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV-CHLM 385
Query: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
G++ + + ++ + K +K QA A +ALAK Y +LF WI+ VN+AL
Sbjct: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
Query: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483
+Q SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
Query: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
W IDF D QPCI LIE + G+L LLDEEC PK TD ++ +KL T F+
Sbjct: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQGSHPKFQ 564
Query: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
KP+ L +K F I H+A KV+Y +L KN D + + +L +S K + +L++D ++
Sbjct: 565 KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
+ + L + +K KG +TVG ++ L LM TL TTP++
Sbjct: 625 IVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTLRNTTPNF 675
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
VRCI PN K D ++QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
Query: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
D KQ C +++ L LD + Y+ G++KIFFR G +A+LE+ R K+ + Q
Sbjct: 736 IPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 795
Query: 776 TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY------- 828
RG+L RK + + R+ +T + + Q C A R ++WR++
Sbjct: 796 MCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLFTKVKPLL 845
Query: 829 -VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
V R+ +++ + ++ R A N +++ ++H + +K + + +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 888 AIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRKVDEQNKD 942
A + R K+EL+++ ++EAR E R ++L K+ Q ++EQ ++
Sbjct: 906 A---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLDLEEQLEE 961
Query: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQT 1002
+ +KL + ++ +KL ++ L + ++ K++ R L L+E I+ L +L +
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDLTTNLAEE 1018
Query: 1003 RSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETM------ 1056
+ K + + ++++ +L LK+E +QE E L ++ A + E +
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
Query: 1057 --EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG 1109
E K+ K+ EL L+DE + N L + LE DL+E++
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
Query: 1110 HKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
K+ + E E S + E R +E + K LD + +V E
Sbjct: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQE 1196
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQELESENK 1216
+ Q+ +EL + EQ R+KA E+E + G EL +QE+E + K
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQEVEHKKK 1255
Query: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQ 1276
KL+ ++ EL+ S+ A L ++ SV+ L+ + + + L + S
Sbjct: 1256 KLEAQVQELQSKCSD--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 1277 KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELW 1336
+Q T + E QK+ ++ Q E R+S D +L+E+ E
Sbjct: 1314 SSQLQD-------TQELLQEETRQKLNVSTKLRQL-----EEERNSLQD--QLDEEME-- 1357
Query: 1337 LVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQNLQLPPEA 1395
+ L++ L QL K+ ++ A +++L+E R Q+++ Q +A
Sbjct: 1358 -AKQNLERHISTLNIQLSDSKKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKA 1412
Query: 1396 RIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
L+ RL E DL+ L+ Q + V L+K+ + F + + E
Sbjct: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Score = 91.7 bits (226), Expect = 6e-18
Identities = 144/668 (21%), Positives = 271/668 (40%), Gaps = 92/668 (13%)
Query: 901 AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940
AK+E+ KK K+EA+ E K G + +K+ +LQ +V+
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 941 --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985
KD L +L + + + ET +KL + QL EE EAK R
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 986 LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
+S L +++ +K L+ S + +EE R+++E E L EE + E +R
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1424
Query: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
+ Q+ ++ ++ + +QL +L ++ ++ LL E + +Y D ++
Sbjct: 1425 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159
+ ++ + E E AEMED+ S ++ + L+ S L+
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1538
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198
++ E++ + + ++DEL E+ LR + EE+R Q++
Sbjct: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
Query: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
ELE E +R + KKL+ +L +L L SA + R L Q+
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1656
Query: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311
EL D R I + ++K+A + D + + E +K D K E+A+
Sbjct: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
Query: 1312 YIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEI 1371
+ +AL + + + + E L++ +E+ + + R +AE L E+
Sbjct: 1717 LAS--SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVRKATQQAEQLSNEL 1773
Query: 1372 ----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQ 1422
+ ++ + +QQL QN +L E +++ + I L + L EQ+E++
Sbjct: 1774 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1833
Query: 1423 DKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1482
+ + K LK KK+ E+ + + + E N + K + LE +E
Sbjct: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEE 1891
Query: 1483 DEQKLVKN 1490
+ Q++ N
Sbjct: 1892 ESQRINAN 1899
Score = 74.7 bits (182), Expect = 8e-13
Identities = 122/587 (20%), Positives = 246/587 (41%), Gaps = 61/587 (10%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
M ++ + ++ +E++K+ ++ ++ ++++N D + L +
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
+ +KL + ++ LQ + + A L +++ KL+ ++E E A + ++
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
L S L++ LL++E ++ LN T ++L EE L+ L++E
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
QNL S L + D K+++ V + G KR + +Y E A D
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1416
Query: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
+T+ ++++ D+ + L Q+++ ++KQ D+L +E+ + A E +R +
Sbjct: 1417 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
Query: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA------------PGAP 1243
E E ++L E + K EL K L + V++
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
Query: 1244 AYRVLMEQLTSVSEEL--DVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTI- 1294
A ME++ + EEL +++ E LR ++ Q + +Q +D++N +
Sbjct: 1536 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595
Query: 1295 --LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ 1352
L E +++D+ + K+ D EL D + E +KQ R L++Q
Sbjct: 1596 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQL-RKLQAQ 1653
Query: 1353 LQSQKRSHENEAEALRGEIQSLKEENNRQQQ-------LLAQNLQLPPEARIEASLQHEI 1405
++ +R E +A A R EI + +EN ++ + L ++L AR +A L+ E
Sbjct: 1654 MKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE- 1711
Query: 1406 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENIS 1452
L E + R+L+ ++ +++ E E G ME +S
Sbjct: 1712 -ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE-EQGNMEAMS 1756
Score = 68.9 bits (167), Expect = 4e-11
Identities = 96/464 (20%), Positives = 191/464 (41%), Gaps = 56/464 (12%)
Query: 989 QEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQ 1048
QEE + ++D Q E+ ++ A+ +E EQ S L EE LL+++ +A + +
Sbjct: 850 QEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELYAE 905
Query: 1049 AKEMTETMEKK---LVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105
A+EM + K L E ++E L +E R Q L E ++ ++ DL+E++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL------ 959
Query: 1106 PKPGHKRTDSTHSSNESEYIFS-SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
+ ++ + E + + ++I ++ED ++ + K L ++ T
Sbjct: 960 -----EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
L +E++ K + + + K K E L+ E RQELE +KL+ + ++
Sbjct: 1015 LAEEEE--------KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1066
Query: 1225 LRKALSEKSAP--EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282
+ +++ A E+ A L L + +E+ +K L +L +Q
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-AQKNNALKKIRELEGHISDLQE 1125
Query: 1283 KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN--EDGELWLVYE 1340
D + + ++ +D GE +A E S EL + E+ ++ +
Sbjct: 1126 DLDSERAARN----KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1181
Query: 1341 GLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1400
L + R E+Q+Q ++ H E L +++ K R +A+
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK--------------------RAKAN 1221
Query: 1401 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
L L EN DL +L + ++++ + K ++ EL+
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Score = 65.1 bits (157), Expect = 6e-10
Identities = 92/354 (25%), Positives = 157/354 (44%), Gaps = 52/354 (14%)
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHI-GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955
+R +A KKL+ + + +E I G E I QL RK+ Q KD++ LE
Sbjct: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQ------RELED 1663
Query: 956 IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR 1015
S E + E +E++AK ++ LQE++A + +Q EK
Sbjct: 1664 ARASRDEIFATAKE----NEKKAKSLEADLMQLQEDLAAAERARKQADLEK--------- 1710
Query: 1016 YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------KKLVEETKQ 1066
++ E+L S+L N L+ EK L RI Q +E+ E ME +K ++ +Q
Sbjct: 1711 -EELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 1067 LELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIF 1126
L +L ER Q + +LE + +L+ ++ M K K T +
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA---------L 1819
Query: 1127 SSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK-EEQVLR 1185
++IA++E+ + E+ + +K SL K K++ E+ ++Q E +RK EQ
Sbjct: 1820 EAKIAQLEE---QVEQEAREKQAATKSLKQK-DKKLKEI-----LLQVEDERKMAEQYKE 1870
Query: 1186 SKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239
K R + +LE + Q + + +KL+ EL+E ++ +E EV A
Sbjct: 1871 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES-NEAMGREVNA 1923
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%)
Query: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Q+ Q+E +Q K+D ++QK K++ + A+ NE
Sbjct: 846 QVTRQEEEMQAKED------------ELQKTKERQQKAE-------------------NE 874
Query: 1332 DGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1391
EL + L + LL+ QLQ++ + EAE +R + + K+E ++ L +L
Sbjct: 875 LKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMRVRLAAKKQE--LEEILHEMEARL 931
Query: 1392 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
E LQ E ++ + LDL EQLE+++ +KL+ + KI +LE
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 594 bits (1532), Expect = e-169
Identities = 435/1453 (29%), Positives = 731/1453 (50%), Gaps = 164/1453 (11%)
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKR 148
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ +
Sbjct: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
Query: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
+ +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 209 EITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
YLLEKSRVVFQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG V +D
Sbjct: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS-ID 327
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 328 DQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
L ++ ++ LC+ ++ E K + Q +NA ALAK +Y K+F W+V +N
Sbjct: 388 AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARIN 447
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Query: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL K A F+
Sbjct: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567
Query: 540 KPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
KP++ + F + H+A V+Y G+LEKNKD + E + + + S K L +LF
Sbjct: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF--- 624
Query: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655
SG A + G+ +TV FR +L+ LM L +T P
Sbjct: 625 -----------SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673
Query: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715
H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 674 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733
Query: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R DKL R
Sbjct: 734 SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793
Query: 773 IQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV 829
Q RG+L R +Y RM R+A +Q +R + K ++ ++++
Sbjct: 794 TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFM---------NVKHWPWMKLFFKIKP 844
Query: 830 VRRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
+ + + + + + + ++ LA++ ++ E K V + K K +
Sbjct: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKE----------KNDL- 893
Query: 888 AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLV 947
++ + E + L ++ K I +E KI ++ + +++ + L
Sbjct: 894 ----------QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
Query: 948 EKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003
K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + +
Sbjct: 944 AKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999
Query: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063
EKK ++E ++Q + L + + NTL K + ++ QQ ++ ++E++
Sbjct: 1000 KEKKALQE---AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEGSLEQE---- 1047
Query: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123
K+L +DL ER + + L + +E D++ E + K + S E E
Sbjct: 1048 -KKLRMDL--ERAK-RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 1124 YIFSSEI-AEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDR---- 1178
++ +++++ +R EE E+++ + + K +K+ ++L +E + + + L+
Sbjct: 1104 QALGIQLQKKIKELQARIEE-LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162
Query: 1179 KEEQVLRSKAKEEE----RPQIRGAELEYESLK------------------------RQE 1210
Q+ +K +E E R + A L++E+ +Q+
Sbjct: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222
Query: 1211 LESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILR 1270
LE E ++K E+++L A + ++ + R L +QL+ EL ++EE L
Sbjct: 1223 LEKEKSEMKMEIDDL--ASNVETVSKAKGNLEKMCRTLEDQLS----ELKSKEEEQQRLI 1276
Query: 1271 SQLVSQKEAIQPK--------DDKNTMTD-----STILLEDVQKMKDK-GEIAQAYIGLK 1316
+ L +Q+ +Q + D+K + + ++++K + E +A L
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 1317 ETNRSSALDYHELNEDGELWLVYEG-LKQANRLLESQLQSQKRSHENEAEALRGEIQSLK 1375
+SS D L E E + L++A +++ + +E +A E++ K
Sbjct: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
Query: 1376 EENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1429
++ LAQ LQ E +E ASL+ RL NE DLM +E+ + L
Sbjct: 1397 KK-------LAQRLQ-AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448
Query: 1430 KKQLKVFAKKIGE 1442
K+ + F K + E
Sbjct: 1449 DKKQRNFDKILAE 1461
Score = 100 bits (248), Expect = 2e-20
Identities = 180/793 (22%), Positives = 324/793 (40%), Gaps = 106/793 (13%)
Query: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903
Q+ RGFLAR Y++++ +A+ IQ +R ++ H+ M ++ + ++
Sbjct: 795 QARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWP-WMKLFFKIKPLLKSAETEK 853
Query: 904 ELKKLKIE--------ARSVERYKKLHIGM-----ENKIMQLQRKVDEQ---NKDYKC-- 945
E+ +K E A+S + K+L M E +QLQ + + + + + +C
Sbjct: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
Query: 946 LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
L++ LE K++ ER + EE T + L++E ++L+KD++
Sbjct: 914 LIKTKIQLEA-------KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
+E+ K TE V NL EE L + L T EKK ++E
Sbjct: 967 LAKVEKE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAH 1009
Query: 1066 QLEL-DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSN 1120
Q L DL E + L +LE++ DD L++E L + + + K +
Sbjct: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
Query: 1121 ESEYIFSSEIAEMEDIPSRTE---EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177
ES +E ++++ + E + K+ + +L ++LQK++ EL+ + +++E++
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Query: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS 1230
+ S+AK E++ ELE S + +E NKK + E ++R+ L
Sbjct: 1130 AER----ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1185
Query: 1231 ------EKSAPEVTAPGAPAYRVLMEQ---LTSVSEELDVRKEEVLILRSQLVSQKEAIQ 1281
E +A + A + L EQ L V ++L+ K E+ + L S E +
Sbjct: 1186 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
Query: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341
K N L + + ++K K E Q I N +A E GE +
Sbjct: 1246 -KAKGNLEKMCRTLEDQLSELKSKEEEQQRLI-----NDLTAQRGRLQTESGE----FSR 1295
Query: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401
L SQL K++ + E L+ ++ EE + + LA LQ +R + L
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQL----EEEIKAKNALAHALQ---SSRHDCDL 1348
Query: 1402 QHEITRLTNEN-LDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDE 1459
E E+ +L L K + V + + + + A ++ ELE + + Q +E
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Query: 1460 PIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAV--------NLIPGLPAY 1511
+ VN LE K+ Q V++L+L+++ A N L +
Sbjct: 1409 HVEAVNAK------CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462
Query: 1512 ILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQY 1571
HA+ ++ RSL T + IK ++ D ET+ N + + L +
Sbjct: 1463 KQKCEETHAELEASQKEARSLGTE-LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1521
Query: 1572 SGEEGFMKHNTSR 1584
E G H +
Sbjct: 1522 IAEGGKRIHELEK 1534
Score = 79.3 bits (194), Expect = 3e-14
Identities = 128/572 (22%), Positives = 246/572 (43%), Gaps = 106/572 (18%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ K+E + ++++ +E + L I ++ KI +LQ +++E +E+ E +
Sbjct: 1086 LKKKEFEISNLQSK-IEDEQALGIQLQKKIKELQARIEE--------LEEEIEAERASRA 1136
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAK----EMT 1053
++HAD + EQ + NL+ L++EK A N V +AK +M
Sbjct: 1197 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255
Query: 1054 ETMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102
T+E +L E E ++L DL +R R Q EFSR + + L +++
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315
Query: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRV 1162
+ + + + + N + S + + + + EE E K L +L K
Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL----SKAN 1371
Query: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
TE+ Q + + + ++ E++ +K K +R Q +E + K LE ++L+NE+
Sbjct: 1372 TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
Query: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL-VSQKEAIQ 1281
+L + +A A L ++ + + L K++ ++L SQKEA
Sbjct: 1432 EDLMLDVERTNA---------ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEA-- 1480
Query: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341
++ T+ + ++ D+ E LK N++ + +L E + EG
Sbjct: 1481 ----RSLGTELFKIKNAYEESLDQLET------LKRENKNLQQEISDLTEQ-----IAEG 1525
Query: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401
K+ + +L+ K+ E E + E+Q+ EE EASL
Sbjct: 1526 GKRIH-----ELEKIKKQVEQE----KCELQAALEE-------------------AEASL 1557
Query: 1402 QHEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433
+HE ++ L+L + + D+ + + +++
Sbjct: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1589
Score = 56.6 bits (135), Expect = 2e-07
Identities = 103/477 (21%), Positives = 204/477 (42%), Gaps = 92/477 (19%)
Query: 904 ELKKLKIEARSV-ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNL---EGIYNS 959
EL+ + EARS+ K+ E + QL+ + +NK+ + + LT G
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLET-LKRENKNLQQEISDLTEQIAEGGKRIH 1530
Query: 960 ETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEKKCIEE 1011
E EK++ +E+ LQ + EEA+ + G++L +Q E+ +++ ++++ +EK +E
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK---DE 1587
Query: 1012 HADRYKQETEQLVSNL----------KEENTLLKQEKEA--------LNHRIVQQAKEMT 1053
D+ K+ ++V ++ + + LK++ E LNH A+ +
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
Query: 1054 ETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPG 1109
+ + + Q+ LD + LR Q L E + ER +L EE+ + +
Sbjct: 1648 NYRNTQGILKDTQIHLD---DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704
Query: 1110 HK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEEPSEKKV 1148
K R H+ N S E S EMEDI +R E KK
Sbjct: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
Query: 1149 PLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIR 1197
D ++ + L++ +EQ + +Q LD E+ L+ K+ ++ + R
Sbjct: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824
Query: 1198 GAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSE 1257
ELE E+ESE K+ + LRK E+ E+T + ++ +L + +
Sbjct: 1825 VRELE------GEVESEQKRNAEAVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVD 1875
Query: 1258 ELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYI 1313
+L + + +++A + ++ NT + L ++++ +++ +IA++ +
Sbjct: 1876 KLQAKVKSY---------KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
Score = 54.3 bits (129), Expect = 1e-06
Identities = 76/339 (22%), Positives = 136/339 (40%), Gaps = 38/339 (11%)
Query: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967
L E RS +L ME + +++ +++ N+ + N +GI L
Sbjct: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666
Query: 968 LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027
L + +E+ + R LQ EI +LR LEQT +K E+ + + V L
Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLL 1722
Query: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078
+NT L K+ L I Q EM + ++ KK + + + +L E+
Sbjct: 1723 HTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782
Query: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138
+L +E+ DL+ + + G K+ + + E+E
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK---------LEARVRELEG--- 1830
Query: 1139 RTEEPSEKKVPLDMSLFL-KLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKE 1190
E SE+K + L K ++RV EL E K ++ QD +D+ + +V K +
Sbjct: 1831 --EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 1888
Query: 1191 EERPQIRGAELEYESLKRQELESENKKL---KNELNELR 1226
EE + L + ELE ++ ++++N+LR
Sbjct: 1889 EEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 594 bits (1532), Expect = e-169
Identities = 435/1453 (29%), Positives = 731/1453 (50%), Gaps = 164/1453 (11%)
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKR 148
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ +
Sbjct: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
Query: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
+ +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 209 EITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
YLLEKSRVVFQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG V +D
Sbjct: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS-ID 327
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 328 DQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
L ++ ++ LC+ ++ E K + Q +NA ALAK +Y K+F W+V +N
Sbjct: 388 AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARIN 447
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Query: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL K A F+
Sbjct: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567
Query: 540 KPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
KP++ + F + H+A V+Y G+LEKNKD + E + + + S K L +LF
Sbjct: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF--- 624
Query: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655
SG A + G+ +TV FR +L+ LM L +T P
Sbjct: 625 -----------SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673
Query: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715
H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 674 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733
Query: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R DKL R
Sbjct: 734 SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793
Query: 773 IQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV 829
Q RG+L R +Y RM R+A +Q +R + K ++ ++++
Sbjct: 794 TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFM---------NVKHWPWMKLFFKIKP 844
Query: 830 VRRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
+ + + + + + + ++ LA++ ++ E K V + K K +
Sbjct: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKE----------KNDL- 893
Query: 888 AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLV 947
++ + E + L ++ K I +E KI ++ + +++ + L
Sbjct: 894 ----------QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
Query: 948 EKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003
K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + +
Sbjct: 944 AKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999
Query: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063
EKK ++E ++Q + L + + NTL K + ++ QQ ++ ++E++
Sbjct: 1000 KEKKALQE---AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEGSLEQE---- 1047
Query: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123
K+L +DL ER + + L + +E D++ E + K + S E E
Sbjct: 1048 -KKLRMDL--ERAK-RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 1124 YIFSSEI-AEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDR---- 1178
++ +++++ +R EE E+++ + + K +K+ ++L +E + + + L+
Sbjct: 1104 QALGIQLQKKIKELQARIEE-LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162
Query: 1179 KEEQVLRSKAKEEE----RPQIRGAELEYESLK------------------------RQE 1210
Q+ +K +E E R + A L++E+ +Q+
Sbjct: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222
Query: 1211 LESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILR 1270
LE E ++K E+++L A + ++ + R L +QL+ EL ++EE L
Sbjct: 1223 LEKEKSEMKMEIDDL--ASNVETVSKAKGNLEKMCRTLEDQLS----ELKSKEEEQQRLI 1276
Query: 1271 SQLVSQKEAIQPK--------DDKNTMTD-----STILLEDVQKMKDK-GEIAQAYIGLK 1316
+ L +Q+ +Q + D+K + + ++++K + E +A L
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 1317 ETNRSSALDYHELNEDGELWLVYEG-LKQANRLLESQLQSQKRSHENEAEALRGEIQSLK 1375
+SS D L E E + L++A +++ + +E +A E++ K
Sbjct: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
Query: 1376 EENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1429
++ LAQ LQ E +E ASL+ RL NE DLM +E+ + L
Sbjct: 1397 KK-------LAQRLQ-AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448
Query: 1430 KKQLKVFAKKIGE 1442
K+ + F K + E
Sbjct: 1449 DKKQRNFDKILAE 1461
Score = 100 bits (248), Expect = 2e-20
Identities = 180/793 (22%), Positives = 324/793 (40%), Gaps = 106/793 (13%)
Query: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903
Q+ RGFLAR Y++++ +A+ IQ +R ++ H+ M ++ + ++
Sbjct: 795 QARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWP-WMKLFFKIKPLLKSAETEK 853
Query: 904 ELKKLKIE--------ARSVERYKKLHIGM-----ENKIMQLQRKVDEQ---NKDYKC-- 945
E+ +K E A+S + K+L M E +QLQ + + + + + +C
Sbjct: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
Query: 946 LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
L++ LE K++ ER + EE T + L++E ++L+KD++
Sbjct: 914 LIKTKIQLEA-------KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
+E+ K TE V NL EE L + L T EKK ++E
Sbjct: 967 LAKVEKE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAH 1009
Query: 1066 QLEL-DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSN 1120
Q L DL E + L +LE++ DD L++E L + + + K +
Sbjct: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
Query: 1121 ESEYIFSSEIAEMEDIPSRTE---EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177
ES +E ++++ + E + K+ + +L ++LQK++ EL+ + +++E++
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Query: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS 1230
+ S+AK E++ ELE S + +E NKK + E ++R+ L
Sbjct: 1130 AER----ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1185
Query: 1231 ------EKSAPEVTAPGAPAYRVLMEQ---LTSVSEELDVRKEEVLILRSQLVSQKEAIQ 1281
E +A + A + L EQ L V ++L+ K E+ + L S E +
Sbjct: 1186 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
Query: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341
K N L + + ++K K E Q I N +A E GE +
Sbjct: 1246 -KAKGNLEKMCRTLEDQLSELKSKEEEQQRLI-----NDLTAQRGRLQTESGE----FSR 1295
Query: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401
L SQL K++ + E L+ ++ EE + + LA LQ +R + L
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQL----EEEIKAKNALAHALQ---SSRHDCDL 1348
Query: 1402 QHEITRLTNEN-LDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDE 1459
E E+ +L L K + V + + + + A ++ ELE + + Q +E
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Query: 1460 PIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAV--------NLIPGLPAY 1511
+ VN LE K+ Q V++L+L+++ A N L +
Sbjct: 1409 HVEAVNAK------CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462
Query: 1512 ILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQY 1571
HA+ ++ RSL T + IK ++ D ET+ N + + L +
Sbjct: 1463 KQKCEETHAELEASQKEARSLGTE-LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1521
Query: 1572 SGEEGFMKHNTSR 1584
E G H +
Sbjct: 1522 IAEGGKRIHELEK 1534
Score = 79.3 bits (194), Expect = 3e-14
Identities = 128/572 (22%), Positives = 246/572 (43%), Gaps = 106/572 (18%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ K+E + ++++ +E + L I ++ KI +LQ +++E +E+ E +
Sbjct: 1086 LKKKEFEISNLQSK-IEDEQALGIQLQKKIKELQARIEE--------LEEEIEAERASRA 1136
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAK----EMT 1053
++HAD + EQ + NL+ L++EK A N V +AK +M
Sbjct: 1197 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255
Query: 1054 ETMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102
T+E +L E E ++L DL +R R Q EFSR + + L +++
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315
Query: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRV 1162
+ + + + + N + S + + + + EE E K L +L K
Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL----SKAN 1371
Query: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
TE+ Q + + + ++ E++ +K K +R Q +E + K LE ++L+NE+
Sbjct: 1372 TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
Query: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL-VSQKEAIQ 1281
+L + +A A L ++ + + L K++ ++L SQKEA
Sbjct: 1432 EDLMLDVERTNA---------ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEA-- 1480
Query: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341
++ T+ + ++ D+ E LK N++ + +L E + EG
Sbjct: 1481 ----RSLGTELFKIKNAYEESLDQLET------LKRENKNLQQEISDLTEQ-----IAEG 1525
Query: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401
K+ + +L+ K+ E E + E+Q+ EE EASL
Sbjct: 1526 GKRIH-----ELEKIKKQVEQE----KCELQAALEE-------------------AEASL 1557
Query: 1402 QHEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433
+HE ++ L+L + + D+ + + +++
Sbjct: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1589
Score = 56.6 bits (135), Expect = 2e-07
Identities = 103/477 (21%), Positives = 204/477 (42%), Gaps = 92/477 (19%)
Query: 904 ELKKLKIEARSV-ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNL---EGIYNS 959
EL+ + EARS+ K+ E + QL+ + +NK+ + + LT G
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLET-LKRENKNLQQEISDLTEQIAEGGKRIH 1530
Query: 960 ETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEKKCIEE 1011
E EK++ +E+ LQ + EEA+ + G++L +Q E+ +++ ++++ +EK +E
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK---DE 1587
Query: 1012 HADRYKQETEQLVSNL----------KEENTLLKQEKEA--------LNHRIVQQAKEMT 1053
D+ K+ ++V ++ + + LK++ E LNH A+ +
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
Query: 1054 ETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPG 1109
+ + + Q+ LD + LR Q L E + ER +L EE+ + +
Sbjct: 1648 NYRNTQGILKDTQIHLD---DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704
Query: 1110 HK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEEPSEKKV 1148
K R H+ N S E S EMEDI +R E KK
Sbjct: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
Query: 1149 PLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIR 1197
D ++ + L++ +EQ + +Q LD E+ L+ K+ ++ + R
Sbjct: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824
Query: 1198 GAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSE 1257
ELE E+ESE K+ + LRK E+ E+T + ++ +L + +
Sbjct: 1825 VRELE------GEVESEQKRNAEAVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVD 1875
Query: 1258 ELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYI 1313
+L + + +++A + ++ NT + L ++++ +++ +IA++ +
Sbjct: 1876 KLQAKVKSY---------KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
Score = 54.3 bits (129), Expect = 1e-06
Identities = 76/339 (22%), Positives = 136/339 (40%), Gaps = 38/339 (11%)
Query: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967
L E RS +L ME + +++ +++ N+ + N +GI L
Sbjct: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666
Query: 968 LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027
L + +E+ + R LQ EI +LR LEQT +K E+ + + V L
Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLL 1722
Query: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078
+NT L K+ L I Q EM + ++ KK + + + +L E+
Sbjct: 1723 HTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782
Query: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138
+L +E+ DL+ + + G K+ + + E+E
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK---------LEARVRELEG--- 1830
Query: 1139 RTEEPSEKKVPLDMSLFL-KLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKE 1190
E SE+K + L K ++RV EL E K ++ QD +D+ + +V K +
Sbjct: 1831 --EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 1888
Query: 1191 EERPQIRGAELEYESLKRQELESENKKL---KNELNELR 1226
EE + L + ELE ++ ++++N+LR
Sbjct: 1889 EEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 593 bits (1528), Expect = e-169
Identities = 464/1494 (31%), Positives = 745/1494 (49%), Gaps = 127/1494 (8%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P ++ +++A + ++ GD+V++ +E GK + D K NP
Sbjct: 36 VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V +NPY+ LPIY E I++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA----- 187
+M PHI+A+A+ AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 188 ---------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGAN 238
+ +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN
Sbjct: 208 TSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 267
Query: 239 MRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEG 298
+ TYLLEKSR + QA +ER +HIFY + A AK L L +N+ + G P+
Sbjct: 268 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 327
Query: 299 VDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPL 357
DD + T +A ++G SE Q+ I ++++ +L LGN+ F R+ D ++P
Sbjct: 328 QDD-EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQ 386
Query: 358 CIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVD 417
+ C LMG++ + + ++ + K +K QA A +ALAK Y +LF WI+
Sbjct: 387 KV-CHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 418 NVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEE 476
VN+AL +Q SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 477 YMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
Y +E I W IDF D QPCI LIE + G+L LLDEEC PK TD ++ +KL T
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQ 564
Query: 533 NKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPE 590
F+KP+ L +K F I H+A KV+Y +L KN D + + +L +S K + +
Sbjct: 565 GSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVAD 624
Query: 591 LFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETL 650
L++D ++ + + L + +K KG +TVG ++ L LM TL
Sbjct: 625 LWKDVDRIVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTL 675
Query: 651 NATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRY 710
TTP++VRCI PN K D ++QLR GVLE IRI GFP+R +QEF RY
Sbjct: 676 RNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 735
Query: 711 RVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRA 768
+L D KQ C +++ L LD + Y+ G++KIFFR G +A+LE+ R K+
Sbjct: 736 EILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITD 795
Query: 769 ACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY 828
+ Q RG+L RK + + R+ +T + + Q C A R ++WR++
Sbjct: 796 VIMAFQAMCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLF 845
Query: 829 --------VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLART 880
V R+ +++ + ++ R A N +++ ++H + +K + +
Sbjct: 846 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 905
Query: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRK 935
+ A + R K+EL+++ ++EAR E R ++L K+ Q
Sbjct: 906 ETELYAEA---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLD 961
Query: 936 VDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKL 995
++EQ ++ + +KL + ++ +KL ++ L + ++ K++ R L L+E I+ L
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDL 1018
Query: 996 RKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTET 1055
+L + + K + + ++++ +L LK+E +QE E L ++ A + E
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQ 1077
Query: 1056 M--------EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLM 1102
+ E K+ K+ EL L+DE + N L + LE DL+E++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 1103 VHVPKPGHKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK 1157
K+ + E E S + E R +E + K LD
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RS 1196
Query: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQ 1209
+ +V E+ Q+ +EL + EQ R+KA E+E + G EL +Q
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQ 1255
Query: 1210 ELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLIL 1269
E+E + KKL+ ++ EL+ S+ A L ++ SV+ L+ + + + L
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSD--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 1270 RSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHEL 1329
+ S +Q T + E QK+ ++ Q E R+S D +L
Sbjct: 1314 AKDVASLSSQLQD-------TQELLQEETRQKLNVSTKLRQL-----EEERNSLQD--QL 1359
Query: 1330 NEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQN 1388
+E+ E + L++ L QL K+ ++ A +++L+E R Q+++
Sbjct: 1360 DEEME---AKQNLERHISTLNIQLSDSKKKLQDFAST----VEALEEGKKRFQKEIENLT 1412
Query: 1389 LQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Q +A L+ RL E DL+ L+ Q + V L+K+ + F + + E
Sbjct: 1413 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Score = 91.7 bits (226), Expect = 6e-18
Identities = 144/668 (21%), Positives = 271/668 (40%), Gaps = 92/668 (13%)
Query: 901 AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940
AK+E+ KK K+EA+ E K G + +K+ +LQ +V+
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 941 --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985
KD L +L + + + ET +KL + QL EE EAK R
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 986 LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
+S L +++ +K L+ S + +EE R+++E E L EE + E +R
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1431
Query: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
+ Q+ ++ ++ + +QL +L ++ ++ LL E + +Y D ++
Sbjct: 1432 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1486
Query: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159
+ ++ + E E AEMED+ S ++ + L+ S L+
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1545
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198
++ E++ + + ++DEL E+ LR + EE+R Q++
Sbjct: 1546 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1605
Query: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
ELE E +R + KKL+ +L +L L SA + R L Q+
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1663
Query: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311
EL D R I + ++K+A + D + + E +K D K E+A+
Sbjct: 1664 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723
Query: 1312 YIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEI 1371
+ +AL + + + + E L++ +E+ + + R +AE L E+
Sbjct: 1724 LAS--SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVRKATQQAEQLSNEL 1780
Query: 1372 ----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQ 1422
+ ++ + +QQL QN +L E +++ + I L + L EQ+E++
Sbjct: 1781 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1840
Query: 1423 DKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1482
+ + K LK KK+ E+ + + + E N + K + LE +E
Sbjct: 1841 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEE 1898
Query: 1483 DEQKLVKN 1490
+ Q++ N
Sbjct: 1899 ESQRINAN 1906
Score = 74.7 bits (182), Expect = 8e-13
Identities = 122/587 (20%), Positives = 246/587 (41%), Gaps = 61/587 (10%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
M ++ + ++ +E++K+ ++ ++ ++++N D + L +
Sbjct: 1204 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1259
Query: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
+ +KL + ++ LQ + + A L +++ KL+ ++E E A + ++
Sbjct: 1260 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
L S L++ LL++E ++ LN T ++L EE L+ L++E
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
QNL S L + D K+++ V + G KR + +Y E A D
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1423
Query: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
+T+ ++++ D+ + L Q+++ ++KQ D+L +E+ + A E +R +
Sbjct: 1424 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1482
Query: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA------------PGAP 1243
E E ++L E + K EL K L + V++
Sbjct: 1483 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1542
Query: 1244 AYRVLMEQLTSVSEEL--DVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTI- 1294
A ME++ + EEL +++ E LR ++ Q + +Q +D++N +
Sbjct: 1543 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1602
Query: 1295 --LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ 1352
L E +++D+ + K+ D EL D + E +KQ R L++Q
Sbjct: 1603 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQL-RKLQAQ 1660
Query: 1353 LQSQKRSHENEAEALRGEIQSLKEENNRQQQ-------LLAQNLQLPPEARIEASLQHEI 1405
++ +R E +A A R EI + +EN ++ + L ++L AR +A L+ E
Sbjct: 1661 MKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE- 1718
Query: 1406 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENIS 1452
L E + R+L+ ++ +++ E E G ME +S
Sbjct: 1719 -ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE-EQGNMEAMS 1763
Score = 68.9 bits (167), Expect = 4e-11
Identities = 96/464 (20%), Positives = 191/464 (41%), Gaps = 56/464 (12%)
Query: 989 QEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQ 1048
QEE + ++D Q E+ ++ A+ +E EQ S L EE LL+++ +A + +
Sbjct: 857 QEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELYAE 912
Query: 1049 AKEMTETMEKK---LVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105
A+EM + K L E ++E L +E R Q L E ++ ++ DL+E++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL------ 966
Query: 1106 PKPGHKRTDSTHSSNESEYIFS-SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
+ ++ + E + + ++I ++ED ++ + K L ++ T
Sbjct: 967 -----EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
L +E++ K + + + K K E L+ E RQELE +KL+ + ++
Sbjct: 1022 LAEEEE--------KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1073
Query: 1225 LRKALSEKSAP--EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282
+ +++ A E+ A L L + +E+ +K L +L +Q
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-AQKNNALKKIRELEGHISDLQE 1132
Query: 1283 KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN--EDGELWLVYE 1340
D + + ++ +D GE +A E S EL + E+ ++ +
Sbjct: 1133 DLDSERAARN----KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1188
Query: 1341 GLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1400
L + R E+Q+Q ++ H E L +++ K R +A+
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK--------------------RAKAN 1228
Query: 1401 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
L L EN DL +L + ++++ + K ++ EL+
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Score = 67.0 bits (162), Expect = 2e-10
Identities = 92/385 (23%), Positives = 162/385 (42%), Gaps = 53/385 (13%)
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHI-GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955
+R +A KKL+ + + +E I G E I QL RK+ Q KD++ LE
Sbjct: 1618 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQ------RELED 1670
Query: 956 IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR 1015
S E + E +E++AK ++ LQE++A + +Q EK
Sbjct: 1671 ARASRDEIFATAKE----NEKKAKSLEADLMQLQEDLAAAERARKQADLEK--------- 1717
Query: 1016 YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------KKLVEETKQ 1066
++ E+L S+L N L+ EK L RI Q +E+ E ME +K ++ +Q
Sbjct: 1718 -EELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 1067 LELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIF 1126
L +L ER Q + +LE + +L+ ++ M K K T +
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA---------L 1826
Query: 1127 SSEIAEMEDIPSRTEEPSEKKVPLDMSL---FLKLQKRVTELEQEKQVMQDELDRKE--- 1180
++IA++E+ + E+ + +K SL KL++ + ++E E+++ + ++ E
Sbjct: 1827 EAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 1181 ---EQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEV 1237
+Q+ R + EE Q A + E N+ + E+N L+ L +
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSF 1943
Query: 1238 TAPGAPAYRVLMEQLTSVSEELDVR 1262
R ++E EE D R
Sbjct: 1944 VPSRRSGGRRVIENADGSEEETDTR 1968
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%)
Query: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Q+ Q+E +Q K+D ++QK K++ + A+ NE
Sbjct: 853 QVTRQEEEMQAKED------------ELQKTKERQQKAE-------------------NE 881
Query: 1332 DGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1391
EL + L + LL+ QLQ++ + EAE +R + + K+E ++ L +L
Sbjct: 882 LKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMRVRLAAKKQE--LEEILHEMEARL 938
Query: 1392 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
E LQ E ++ + LDL EQLE+++ +KL+ + KI +LE
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 593 bits (1528), Expect = e-169
Identities = 464/1494 (31%), Positives = 745/1494 (49%), Gaps = 127/1494 (8%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P ++ +++A + ++ GD+V++ +E GK + D K NP
Sbjct: 36 VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V +NPY+ LPIY E I++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA----- 187
+M PHI+A+A+ AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 188 ---------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGAN 238
+ +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN
Sbjct: 208 TSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 267
Query: 239 MRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEG 298
+ TYLLEKSR + QA +ER +HIFY + A AK L L +N+ + G P+
Sbjct: 268 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 327
Query: 299 VDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPL 357
DD + T +A ++G SE Q+ I ++++ +L LGN+ F R+ D ++P
Sbjct: 328 QDD-EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQ 386
Query: 358 CIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVD 417
+ C LMG++ + + ++ + K +K QA A +ALAK Y +LF WI+
Sbjct: 387 KV-CHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 418 NVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEE 476
VN+AL +Q SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 477 YMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
Y +E I W IDF D QPCI LIE + G+L LLDEEC PK TD ++ +KL T
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQ 564
Query: 533 NKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPE 590
F+KP+ L +K F I H+A KV+Y +L KN D + + +L +S K + +
Sbjct: 565 GSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVAD 624
Query: 591 LFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETL 650
L++D ++ + + L + +K KG +TVG ++ L LM TL
Sbjct: 625 LWKDVDRIVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTL 675
Query: 651 NATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRY 710
TTP++VRCI PN K D ++QLR GVLE IRI GFP+R +QEF RY
Sbjct: 676 RNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 735
Query: 711 RVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRA 768
+L D KQ C +++ L LD + Y+ G++KIFFR G +A+LE+ R K+
Sbjct: 736 EILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITD 795
Query: 769 ACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY 828
+ Q RG+L RK + + R+ +T + + Q C A R ++WR++
Sbjct: 796 VIMAFQAMCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLF 845
Query: 829 --------VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLART 880
V R+ +++ + ++ R A N +++ ++H + +K + +
Sbjct: 846 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 905
Query: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRK 935
+ A + R K+EL+++ ++EAR E R ++L K+ Q
Sbjct: 906 ETELYAEA---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLD 961
Query: 936 VDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKL 995
++EQ ++ + +KL + ++ +KL ++ L + ++ K++ R L L+E I+ L
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDL 1018
Query: 996 RKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTET 1055
+L + + K + + ++++ +L LK+E +QE E L ++ A + E
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQ 1077
Query: 1056 M--------EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLM 1102
+ E K+ K+ EL L+DE + N L + LE DL+E++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 1103 VHVPKPGHKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK 1157
K+ + E E S + E R +E + K LD
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RS 1196
Query: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQ 1209
+ +V E+ Q+ +EL + EQ R+KA E+E + G EL +Q
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQ 1255
Query: 1210 ELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLIL 1269
E+E + KKL+ ++ EL+ S+ A L ++ SV+ L+ + + + L
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSD--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 1270 RSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHEL 1329
+ S +Q T + E QK+ ++ Q E R+S D +L
Sbjct: 1314 AKDVASLSSQLQD-------TQELLQEETRQKLNVSTKLRQL-----EEERNSLQD--QL 1359
Query: 1330 NEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQN 1388
+E+ E + L++ L QL K+ ++ A +++L+E R Q+++
Sbjct: 1360 DEEME---AKQNLERHISTLNIQLSDSKKKLQDFAST----VEALEEGKKRFQKEIENLT 1412
Query: 1389 LQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Q +A L+ RL E DL+ L+ Q + V L+K+ + F + + E
Sbjct: 1413 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Score = 91.7 bits (226), Expect = 6e-18
Identities = 144/668 (21%), Positives = 271/668 (40%), Gaps = 92/668 (13%)
Query: 901 AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940
AK+E+ KK K+EA+ E K G + +K+ +LQ +V+
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 941 --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985
KD L +L + + + ET +KL + QL EE EAK R
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 986 LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
+S L +++ +K L+ S + +EE R+++E E L EE + E +R
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1431
Query: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
+ Q+ ++ ++ + +QL +L ++ ++ LL E + +Y D ++
Sbjct: 1432 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1486
Query: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159
+ ++ + E E AEMED+ S ++ + L+ S L+
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1545
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198
++ E++ + + ++DEL E+ LR + EE+R Q++
Sbjct: 1546 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1605
Query: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
ELE E +R + KKL+ +L +L L SA + R L Q+
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1663
Query: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311
EL D R I + ++K+A + D + + E +K D K E+A+
Sbjct: 1664 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723
Query: 1312 YIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEI 1371
+ +AL + + + + E L++ +E+ + + R +AE L E+
Sbjct: 1724 LAS--SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVRKATQQAEQLSNEL 1780
Query: 1372 ----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQ 1422
+ ++ + +QQL QN +L E +++ + I L + L EQ+E++
Sbjct: 1781 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1840
Query: 1423 DKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1482
+ + K LK KK+ E+ + + + E N + K + LE +E
Sbjct: 1841 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEE 1898
Query: 1483 DEQKLVKN 1490
+ Q++ N
Sbjct: 1899 ESQRINAN 1906
Score = 74.7 bits (182), Expect = 8e-13
Identities = 122/587 (20%), Positives = 246/587 (41%), Gaps = 61/587 (10%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
M ++ + ++ +E++K+ ++ ++ ++++N D + L +
Sbjct: 1204 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1259
Query: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
+ +KL + ++ LQ + + A L +++ KL+ ++E E A + ++
Sbjct: 1260 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
L S L++ LL++E ++ LN T ++L EE L+ L++E
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
QNL S L + D K+++ V + G KR + +Y E A D
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1423
Query: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
+T+ ++++ D+ + L Q+++ ++KQ D+L +E+ + A E +R +
Sbjct: 1424 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1482
Query: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA------------PGAP 1243
E E ++L E + K EL K L + V++
Sbjct: 1483 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1542
Query: 1244 AYRVLMEQLTSVSEEL--DVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTI- 1294
A ME++ + EEL +++ E LR ++ Q + +Q +D++N +
Sbjct: 1543 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1602
Query: 1295 --LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ 1352
L E +++D+ + K+ D EL D + E +KQ R L++Q
Sbjct: 1603 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQL-RKLQAQ 1660
Query: 1353 LQSQKRSHENEAEALRGEIQSLKEENNRQQQ-------LLAQNLQLPPEARIEASLQHEI 1405
++ +R E +A A R EI + +EN ++ + L ++L AR +A L+ E
Sbjct: 1661 MKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE- 1718
Query: 1406 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENIS 1452
L E + R+L+ ++ +++ E E G ME +S
Sbjct: 1719 -ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE-EQGNMEAMS 1763
Score = 68.9 bits (167), Expect = 4e-11
Identities = 96/464 (20%), Positives = 191/464 (41%), Gaps = 56/464 (12%)
Query: 989 QEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQ 1048
QEE + ++D Q E+ ++ A+ +E EQ S L EE LL+++ +A + +
Sbjct: 857 QEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELYAE 912
Query: 1049 AKEMTETMEKK---LVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105
A+EM + K L E ++E L +E R Q L E ++ ++ DL+E++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL------ 966
Query: 1106 PKPGHKRTDSTHSSNESEYIFS-SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
+ ++ + E + + ++I ++ED ++ + K L ++ T
Sbjct: 967 -----EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
L +E++ K + + + K K E L+ E RQELE +KL+ + ++
Sbjct: 1022 LAEEEE--------KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1073
Query: 1225 LRKALSEKSAP--EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282
+ +++ A E+ A L L + +E+ +K L +L +Q
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-AQKNNALKKIRELEGHISDLQE 1132
Query: 1283 KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN--EDGELWLVYE 1340
D + + ++ +D GE +A E S EL + E+ ++ +
Sbjct: 1133 DLDSERAARN----KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1188
Query: 1341 GLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1400
L + R E+Q+Q ++ H E L +++ K R +A+
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK--------------------RAKAN 1228
Query: 1401 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
L L EN DL +L + ++++ + K ++ EL+
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Score = 65.1 bits (157), Expect = 6e-10
Identities = 92/354 (25%), Positives = 157/354 (44%), Gaps = 52/354 (14%)
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHI-GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955
+R +A KKL+ + + +E I G E I QL RK+ Q KD++ LE
Sbjct: 1618 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQ------RELED 1670
Query: 956 IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR 1015
S E + E +E++AK ++ LQE++A + +Q EK
Sbjct: 1671 ARASRDEIFATAKE----NEKKAKSLEADLMQLQEDLAAAERARKQADLEK--------- 1717
Query: 1016 YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------KKLVEETKQ 1066
++ E+L S+L N L+ EK L RI Q +E+ E ME +K ++ +Q
Sbjct: 1718 -EELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 1067 LELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIF 1126
L +L ER Q + +LE + +L+ ++ M K K T +
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA---------L 1826
Query: 1127 SSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK-EEQVLR 1185
++IA++E+ + E+ + +K SL K K++ E+ ++Q E +RK EQ
Sbjct: 1827 EAKIAQLEE---QVEQEAREKQAATKSLKQK-DKKLKEI-----LLQVEDERKMAEQYKE 1877
Query: 1186 SKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239
K R + +LE + Q + + +KL+ EL+E ++ +E EV A
Sbjct: 1878 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES-NEAMGREVNA 1930
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%)
Query: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Q+ Q+E +Q K+D ++QK K++ + A+ NE
Sbjct: 853 QVTRQEEEMQAKED------------ELQKTKERQQKAE-------------------NE 881
Query: 1332 DGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1391
EL + L + LL+ QLQ++ + EAE +R + + K+E ++ L +L
Sbjct: 882 LKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMRVRLAAKKQE--LEEILHEMEARL 938
Query: 1392 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
E LQ E ++ + LDL EQLE+++ +KL+ + KI +LE
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 592 bits (1527), Expect = e-169
Identities = 454/1560 (29%), Positives = 762/1560 (48%), Gaps = 141/1560 (9%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
V++ +P+E + + + K G KV + E G L D + P NP
Sbjct: 40 VFVAEPKESYVKSTIQS--KEGGKVTV-KTEGGATLTVRED---QVFP--MNPPKYDKIE 91
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ +++LHEP VL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 92 DMAMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKR 150
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ +
Sbjct: 151 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKD 210
Query: 189 -----EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
+ +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 211 ESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270
Query: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVDDA 302
LEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG + +DD
Sbjct: 271 LEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQ 329
Query: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
+E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 330 EELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
Query: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
L ++ ++ LC+ ++ E K + Q NA ALAK +Y K+F W+V +NQ
Sbjct: 390 LQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQ 449
Query: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 450 LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509
Query: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
WT IDF D CI LIE LGI +L+EEC PK TD ++ KLY+ HL K A F+KP
Sbjct: 510 EWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569
Query: 542 RL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
++ + F + H+A V+Y G+L+KNKD + + + + + S K L LF
Sbjct: 570 KVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYAS 629
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
A + +SA + KG Q TV FR +L+ LM L +T PH+
Sbjct: 630 AEADSSAKKGAKK----------KGSSFQ-------TVSALFRENLNKLMTNLRSTHPHF 672
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 673 VRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASA 732
Query: 717 --KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQ 774
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL R Q
Sbjct: 733 IPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQ 792
Query: 775 KTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVR 831
RG+L+R +Y +M R+A +Q VR + K ++ ++++ +
Sbjct: 793 AVCRGFLMRVEYQKMLQRREALFCIQYNVRAFM---------NVKHWPWMKLFFKIKPLL 843
Query: 832 RRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAI 889
+ + + + + + + LA++ ++ E K V + K + + A
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 890 IYLQCCFRRMMAKRELK---KLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCL 946
+C + K +++ K+K E ++++ + K +L+ + E KD L
Sbjct: 904 AEERC---EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 947 VEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEK 1006
L +E ++ K+++ E + +E + +LQE + DL+ +
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 1007 KCIEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063
+ + + +Q+ + L +L++E L L++ K L + + A+E T ME +
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL-KLAQESTMDME----ND 1075
Query: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKPGHKRTDSTHSSNES 1122
+QL+ L + NL+++ + L++++ L + + G + S ++
Sbjct: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135
Query: 1123 EYIFSSEIAEMEDIPSRTEE---PSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK 1179
E S E+E+I R EE + +V L+ +KR E ++ ++ +++ +
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELN-------KKREAEFQKLRRDLEEATLQH 1188
Query: 1180 EEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239
E V + K + G +++ +Q+LE E +LK E ++L S E +
Sbjct: 1189 EAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL------SSNAEAIS 1242
Query: 1240 PGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPK--------DDKNTMTD 1291
+ L EL ++EE L + L +Q+ +Q + D+K+ +
Sbjct: 1243 KAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS 1302
Query: 1292 --------STILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLK 1343
ST +E+++ + E +A L +SS D L E E EG
Sbjct: 1303 QLSRSKQASTQQIEELKHQLE--EETKAKNALAHALQSSRHDCDLLREQYE--EEQEGKA 1358
Query: 1344 QANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE-- 1398
+ R L S++ + +E +A E++ K++ LAQ LQ E +E
Sbjct: 1359 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK-------LAQRLQ-EAEEHVEAV 1410
Query: 1399 ----ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI-----------GEL 1443
ASL+ RL NE DLM +E+ + L K+ + F K + EL
Sbjct: 1411 NAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL 1470
Query: 1444 EVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVN 1503
E Q E+ S + E + N+ + D L + ++ Q+ + +L ++ G ++
Sbjct: 1471 EASQKESRS---LSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIH 1527
Score = 84.7 bits (208), Expect = 7e-16
Identities = 127/570 (22%), Positives = 246/570 (43%), Gaps = 103/570 (18%)
Query: 902 KRELKKLKIE--ARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
K E K+ +I +E + + I ++ KI +LQ +++E ++ + E +
Sbjct: 1082 KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEA--------ERASRA 1133
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EK RSDL R ++SE EEA AT + L + E KLR+DLE+ + + +
Sbjct: 1134 KAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVA 1193
Query: 1010 ---EEHADRYKQETEQLVS------NLKEENTLLKQEKEAL--NHRIVQQAKEMTETMEK 1058
++HAD + EQ+ + L++E + LK E + L N + +AK E M +
Sbjct: 1194 ALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCR 1253
Query: 1059 KLVEETKQLEL----------DLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH---- 1104
L ++ +L+ DL +R R Q E+SR + D L +++
Sbjct: 1254 SLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQ 1313
Query: 1105 -VPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVT 1163
+ + H+ + T + N + S + + + + EE E K L +L K +
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL----SKANS 1369
Query: 1164 ELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELN 1223
E+ Q + + + ++ E++ +K K +R Q +E + K LE ++L+NE+
Sbjct: 1370 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 1429
Query: 1224 ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPK 1283
+L + +A A L ++ + + L K++ +++L EA Q K
Sbjct: 1430 DLMLDVERSNA---------ACAALDKKQRNFDKVLSEWKQKYEETQAEL----EASQ-K 1475
Query: 1284 DDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLK 1343
+ ++ T+ + ++ D+ E L+ N++ + +L E + EG K
Sbjct: 1476 ESRSLSTELFKVKNVYEESLDQLET------LRRENKNLQQEISDLTEQ-----IAEGGK 1524
Query: 1344 QANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQH 1403
Q + +L+ K+ E E + EIQ+ EE EASL+H
Sbjct: 1525 QIH-----ELEKIKKQVEQE----KCEIQAALEE-------------------AEASLEH 1556
Query: 1404 EITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433
E ++ L+L + + D+ + + +++
Sbjct: 1557 EEGKILRIQLELNQVKSEVDRKIAEKDEEI 1586
Score = 54.3 bits (129), Expect = 1e-06
Identities = 89/407 (21%), Positives = 172/407 (42%), Gaps = 79/407 (19%)
Query: 896 FRRMMAKRELKKLKIEARSVERYKKLHIGMEN--KIMQLQRKVDEQNKDYKCLVEKLTNL 953
+ A+ E + + + S E +K ++ E+ ++ L+R+ ++ L E++
Sbjct: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE- 1521
Query: 954 EGIYNSETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSE 1005
G E EK++ +E+ +Q + EEA+ + G++L +Q E+ +++ ++++ +E
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581
Query: 1006 KKCIEEHADRYKQETEQLV--------SNLKEENTLLKQEKEA----------LNHRIVQ 1047
K +E D+ K+ ++V + ++ N L+ +K+ LNH
Sbjct: 1582 K---DEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRL 1638
Query: 1048 QAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMV 1103
A+ + + + + QL LD + LR Q L E + ER +L EE+ +
Sbjct: 1639 AAESLRNYRNTQGILKETQLHLD---DALRGQEDLKEQLAIVERRANLLQAEIEELWATL 1695
Query: 1104 HVPKPGHK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEE 1142
+ K R H+ N S E S +E+E++ SR E
Sbjct: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755
Query: 1143 PSEKKVPLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEE 1191
KK D ++ + L++ LEQ + +Q LD E+ L+ K+
Sbjct: 1756 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1815
Query: 1192 ERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVT 1238
++ + R ELE E+E+E K+ + LRK E+ E+T
Sbjct: 1816 QKLEARVRELE------GEVENEQKRNAEAVKGLRK--HERRVKELT 1854
Score = 54.3 bits (129), Expect = 1e-06
Identities = 73/338 (21%), Positives = 135/338 (39%), Gaps = 36/338 (10%)
Query: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967
L E RS ++ ME + +++ +++ N+ + N +GI L
Sbjct: 1604 LDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDA 1663
Query: 968 LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027
L + +E+ + R LQ EI +L LEQT +K E+ + + V L
Sbjct: 1664 LRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQEL----LDASERVQLL 1719
Query: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078
+NT L K+ L + + Q E+ E ++ KK + + + +L E+
Sbjct: 1720 HTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS 1779
Query: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138
+L LE+ DL+ + + G K+ + + E+E
Sbjct: 1780 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK---------LEARVRELEG--- 1827
Query: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKEE 1191
E +K+ + K ++RV EL E K V+ QD +D+ + +V K + E
Sbjct: 1828 -EVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
Query: 1192 ERPQIRGAELEYESLKRQELESENKK---LKNELNELR 1226
E + A L + ELE ++ ++++N+LR
Sbjct: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLR 1924
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 590 bits (1521), Expect = e-168
Identities = 434/1463 (29%), Positives = 718/1463 (49%), Gaps = 186/1463 (12%)
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKR 148
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ +
Sbjct: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
Query: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
+ +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 209 EPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 268
Query: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
YLLEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N +F + QG + +D
Sbjct: 269 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQG-EITVPSID 327
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 328 DQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
L ++ ++ LC+ ++ E K + Q NA ALAK IY K+F W+V +N
Sbjct: 388 AYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRIN 447
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Query: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
I W IDF D CI LIE +GI +L+EEC PK TD ++ KLY HL K F+
Sbjct: 508 GIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
Query: 540 KPRLS----NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
KP+ + F + H+A V+Y G+L+KNKD + E + + + S K L LF
Sbjct: 568 KPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA 627
Query: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655
+ A + G G+ +TV FR +L+ LM L +T P
Sbjct: 628 QTAEAEGGGGKKG----------------GKKKGSSFQTVSALFRENLNKLMTNLRSTHP 671
Query: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715
H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 672 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 731
Query: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL R
Sbjct: 732 SAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITR 791
Query: 773 IQKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQ-------ARCYAKFLRRTKAATIIQ 822
Q RG+L+R +K + R++ +Q +R + + Y K K+A +
Sbjct: 792 TQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEK 851
Query: 823 KYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHY 882
+ M + K A T RK L E ++Q+
Sbjct: 852 EMANMKEEFEKTKEELAKT-------------EAKRKELEEKMVTLMQE----------- 887
Query: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942
K + ++ + E L ++ K I +E KI ++ + +++ +
Sbjct: 888 KNDL-----------QLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936
Query: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKD 998
L K LE E +L+ D++ L+L+ E+E +V +L EE+A L +
Sbjct: 937 NAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDET 992
Query: 999 LEQTRSEKKCIEE---------------------HADRYKQETEQLVSNLKEENTL---L 1034
+ + EKK ++E + +Q+ + L +L++E L L
Sbjct: 993 IAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDL 1052
Query: 1035 KQEKEAL--NHRIVQQAKEMTETMEKKLVEETKQLELDLN-------DERLRYQNLLNEF 1085
++ K L + ++ Q++ TE +++L E+ K+ E +++ DE+ L +
Sbjct: 1053 ERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKI 1112
Query: 1086 SRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP-S 1144
L+ R ++L+EE+ S ++E S E+E+I R EE
Sbjct: 1113 KELQARIEELEEEIEA-------------ERASRAKAEKQRSDLSRELEEISERLEEAGG 1159
Query: 1145 EKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYE 1204
++M+ +KR E ++ ++ +++ + E + K + G +++
Sbjct: 1160 ATSAQIEMN-----KKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSL 1214
Query: 1205 SLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKE 1264
+Q+LE E +LK E+N+L A + ++ + A R L +QL+ E+ ++E
Sbjct: 1215 QRVKQKLEKEKSELKMEINDL--ASNMETVSKAKANFEKMCRTLEDQLS----EIKTKEE 1268
Query: 1265 EVLILRSQLVSQKEAIQPK--------DDKNTMTDS--------TILLEDVQKMKDKGEI 1308
E L ++L +QK + + D+K+ M T +E++++ ++
Sbjct: 1269 EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328
Query: 1309 AQAYI--GLKETNRSSALDYHELNEDGELWL-VYEGLKQANRLLESQLQSQKRSHENEAE 1365
A++ + L+ L + E+ E + G+ +AN S++ + +E +A
Sbjct: 1329 AKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKAN----SEVAQWRTKYETDAI 1384
Query: 1366 ALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQL 1419
E++ K++ LAQ LQ E +E ASL+ RL NE DLM +
Sbjct: 1385 QRTEELEEAKKK-------LAQRLQ-DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDV 1436
Query: 1420 EKQDKTVRKLKKQLKVFAKKIGE 1442
E+ + L K+ + F K + E
Sbjct: 1437 ERSNAACIALDKKQRNFDKVLAE 1459
Score = 98.2 bits (243), Expect = 7e-20
Identities = 162/702 (23%), Positives = 296/702 (42%), Gaps = 97/702 (13%)
Query: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903
Q+ RGFL R +RK++ +++ IQ +R ++ H+ M ++ + ++
Sbjct: 793 QAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWP-WMKLYFKIKPLLKSAETEK 851
Query: 904 ELKKL------------KIEARSVERYKKLHIGMENK---IMQLQRKVDE-QNKDYKC-- 945
E+ + K EA+ E +K+ M+ K +Q+Q + D + + +C
Sbjct: 852 EMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQ 911
Query: 946 LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
L++ LE K++ ER + EE T + L++E ++L+KD++
Sbjct: 912 LIKTKIQLEA-------KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
+E+ K TE V NL EE L + L T EKK ++E
Sbjct: 965 LAKVEKE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAH 1007
Query: 1066 QLEL-DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSN 1120
Q L DL E + L ++LE++ DD L++E L + + + K +
Sbjct: 1008 QQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067
Query: 1121 ESEYIFSSEIAEM-EDIPSRTEEPS--EKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177
ES ++ ++ E + + E S + K+ + +L ++LQK++ EL+ + +++E++
Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIE 1127
Query: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS 1230
+ S+AK E++ ELE S + +E NKK + E ++R+ L
Sbjct: 1128 AER----ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 1231 EKSAP-EVTAPG-----APAYRVLMEQLTS---VSEELDVRKEEVLILRSQLVSQKEAIQ 1281
E + E TA A + L EQ+ S V ++L+ K E+ + + L S E +
Sbjct: 1184 ESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVS 1243
Query: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341
K N L + + ++K K E Q I N SA E GE +
Sbjct: 1244 -KAKANFEKMCRTLEDQLSEIKTKEEEQQRLI-----NELSAQKARLHTESGE----FSR 1293
Query: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401
+ SQL K++ + E L+ ++ EE + + LA LQ AR + L
Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQL----EEETKAKSTLAHALQ---SARHDCDL 1346
Query: 1402 QHEITRLTNE-NLDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDE 1459
E E +L + K + V + + + + A ++ ELE + + Q +E
Sbjct: 1347 LREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
Query: 1460 PIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVA 1501
+ VN LE K+ Q V++L+++++ A
Sbjct: 1407 HVEAVN------SKCASLEKTKQRLQNEVEDLMIDVERSNAA 1442
Score = 82.4 bits (202), Expect = 4e-15
Identities = 165/743 (22%), Positives = 298/743 (40%), Gaps = 172/743 (23%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ K+E + ++ + +E + L I ++ KI +LQ +++E +E+ E +
Sbjct: 1084 LKKKEFEMSNLQGK-IEDEQALAIQLQKKIKELQARIEE--------LEEEIEAERASRA 1134
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE++ + +
Sbjct: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAA 1194
Query: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE--------ALNHRIVQQAK----EMTE 1054
++HAD + EQ+ S + + L K++ E A N V +AK +M
Sbjct: 1195 ALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCR 1254
Query: 1055 TMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSR--------------------- 1087
T+E +L E E ++L +L+ ++ R EFSR
Sbjct: 1255 TLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQ 1314
Query: 1088 -LEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIF-----------SSEIAE 1132
+EE L+EE + + H + D E E +SE+A+
Sbjct: 1315 QIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQ 1374
Query: 1133 ME-----DIPSRTEEPSEKKVPLDMSL------FLKLQKRVTELEQEKQVMQDE------ 1175
D RTEE E K L L + + LE+ KQ +Q+E
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMI 1434
Query: 1176 -----------LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN---- 1220
LD+K+ + A+ +++ + AELE + + L +E K+KN
Sbjct: 1435 DVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE 1494
Query: 1221 -----------------ELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLTSVSE-ELD 1260
E+++L + ++E K E+ E TS+ E E
Sbjct: 1495 SLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEAS 1554
Query: 1261 VRKEEVLILRSQL--------VSQKEAIQPKDDKNTMTDSTILLEDVQ------------ 1300
+ EE ILR QL + +K A + ++ + ++E +Q
Sbjct: 1555 LEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRND 1614
Query: 1301 ----KMKDKGEIAQAYIGLKETNRSSALDYHEL-NEDGELWLVYEGLKQANRLLESQLQS 1355
K K +G++ + I L NR +A L N G L L A R + L+
Sbjct: 1615 ALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIR-GQDDLKE 1673
Query: 1356 QKRSHENEAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN 1412
Q E A ++ E++ L+ E R +++ Q L ++AS + L +N
Sbjct: 1674 QLAMVERRANLMQAEVEELRASLERTERGRKMAEQEL-------LDAS--ERVQLLHTQN 1724
Query: 1413 LDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKD 1472
L+ +K + + +++ +++ ++ E + I+ ++ E + +KE+D
Sbjct: 1725 TSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL------KKEQD 1778
Query: 1473 FQGMLEYKKEDEQKLVKNLILEL 1495
LE K++ ++ VK+L L L
Sbjct: 1779 TSAHLERMKKNMEQTVKDLQLRL 1801
Score = 68.9 bits (167), Expect = 4e-11
Identities = 108/616 (17%), Positives = 257/616 (41%), Gaps = 74/616 (12%)
Query: 877 LARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKV 936
L R Y+ A LQ + ++ + K E +++R ++L E +L +++
Sbjct: 1346 LLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEEL----EEAKKKLAQRL 1401
Query: 937 DEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKL- 995
+ + + + K +LE ++L++++E L + E + A + Q K+
Sbjct: 1402 QDAEEHVEAVNSKCASLE----KTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVL 1457
Query: 996 ----------RKDLEQTRSEKKCIEEHADRYKQETEQLVSNL---KEENTLLKQEKEALN 1042
+ +LE ++ E + + + K E+ + +L K EN L+QE L
Sbjct: 1458 AEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLT 1517
Query: 1043 HRIVQQAKEM--TETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT 1100
+I + K + E ++K+L E +L+ L + ++ + R++ + +K E+
Sbjct: 1518 EQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEID 1577
Query: 1101 LMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK 1160
+ E + + + + +E + S + + L+++K
Sbjct: 1578 RKI------------AEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDA-----LRIKK 1620
Query: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAK-----EEERPQIRGAELEYESLKRQ--ELES 1213
++ E ++ + +R+ + LR+ ++ + + A + LK Q +E
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 1214 ENKKLKNELNELRKALSE-----KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
++ E+ ELR +L K A + + ++L Q TS+ + ++
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 1269 LRSQL--VSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDY 1326
++ ++ + Q+ + K +TD+ ++ E+++K +D + +K+ + D
Sbjct: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKNMEQTVKDL 1797
Query: 1327 HELNEDGELWLVYEGLKQANRL------LESQLQSQKRSHENEAEALRGEIQSLKE---- 1376
++ E + G KQ +L LES+++S+++ + + LR + +KE
Sbjct: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
Query: 1377 -ENNRQQQLLAQNLQLPPEARIEASLQ--HEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433
E +R+ L Q+L + +++A + E +N NL +L+ + + + K++
Sbjct: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHE---LEEAKERA 1914
Query: 1434 KVFAKKIGELEVGQME 1449
+ ++ +L V E
Sbjct: 1915 DIAESQVNKLRVKSRE 1930
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 586 bits (1511), Expect = e-167
Identities = 439/1452 (30%), Positives = 709/1452 (48%), Gaps = 164/1452 (11%)
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKR 148
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFAT---------- 182
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT
Sbjct: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
Query: 183 -VSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
V+ + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 209 EVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
YLLEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG + +D
Sbjct: 269 YLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSID 327
Query: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 328 DQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
Query: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
L ++ ++ LC+ ++ E K + Q NA ALAK +Y K+F W+V +N
Sbjct: 388 AYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRIN 447
Query: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Query: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY HL K F+
Sbjct: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
Query: 540 KPRLS----NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
KP+ + F + H+A V+Y G+L+KNKD + E + + + S K L LF
Sbjct: 568 KPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF--- 624
Query: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHK-KTVGHQFRNSLHLLMETLNATT 654
T A+ G+ G K +TV FR +L+ LM L +T
Sbjct: 625 --------------VGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTH 670
Query: 655 PHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM 714
PH+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 671 PHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLN 730
Query: 715 KQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACI 771
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL
Sbjct: 731 ASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLIT 790
Query: 772 RIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQ-------ARCYAKFLRRTKAATII 821
R Q RG+L R +Y +M R++ +Q VR + + Y K K+A
Sbjct: 791 RTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETE 850
Query: 822 QKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTH 881
++ M + K A T RK L E ++Q+
Sbjct: 851 KEMANMKEEFEKTKEELAKT-------------EAKRKELEEKMVTLMQE---------- 887
Query: 882 YKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNK 941
K + ++ + E L ++ K I +E KI ++ + +++ +
Sbjct: 888 -KNDL-----------QLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 935
Query: 942 DYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRK 997
L K LE E +L+ D++ L+L+ E+E +V +L EE+A L +
Sbjct: 936 INAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 991
Query: 998 DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQ---------------EKEALN 1042
+ + EKK ++E ++Q + L + + NTL K E+E
Sbjct: 992 TIAKLTKEKKALQE---AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKI 1048
Query: 1043 HRIVQQAKEMTETMEKKLVEETKQLELDLN--DERLRYQNLLNEFSRLEERYDD------ 1094
+++AK E K E T +E D DE+L+ + E S L+ + +D
Sbjct: 1049 RMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF--EMSGLQSKIEDEQALGM 1106
Query: 1095 --LKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP-SEKKVPLD 1151
K+ L + + + S ++E S E+E+I R EE ++
Sbjct: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
Query: 1152 MSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQEL 1211
M+ +KR E ++ ++ +++ + E + K + G +++ +Q+L
Sbjct: 1167 MN-----KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
Query: 1212 ESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRS 1271
E E ++K E+++L A + ++ + R L +QL+ E+ ++EE L +
Sbjct: 1222 EKEKSEMKMEIDDL--ASNMETVSKAKGNLEKMCRALEDQLS----EIKTKEEEQQRLIN 1275
Query: 1272 QLVSQKEAIQPK--------DDKNTMTD-----STILLEDVQKMKDK-GEIAQAYIGLKE 1317
L +Q+ +Q + D+K+T+ + ++++K + E +A L
Sbjct: 1276 DLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAH 1335
Query: 1318 TNRSSALDYHELNEDGELWLVYEG-LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKE 1376
+SS D L E E + L++A S++ + +E +A E++ K+
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
Query: 1377 ENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKLK 1430
+ LAQ LQ E +E ASL+ RL NE DLM +E+ + L
Sbjct: 1396 K-------LAQRLQ-DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALD 1447
Query: 1431 KQLKVFAKKIGE 1442
K+ + F K + E
Sbjct: 1448 KKQRNFDKILAE 1459
Score = 97.4 bits (241), Expect = 1e-19
Identities = 175/792 (22%), Positives = 320/792 (40%), Gaps = 104/792 (13%)
Query: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903
Q+ RGFLAR Y+K++ +++ IQ VR ++ H+ M ++ + ++
Sbjct: 793 QAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWP-WMKLYFKIKPLLKSAETEK 851
Query: 904 ELKKL------------KIEARSVERYKKLHIGMENK---IMQLQRKVDE-QNKDYKC-- 945
E+ + K EA+ E +K+ M+ K +Q+Q + D + + +C
Sbjct: 852 EMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQ 911
Query: 946 LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
L++ LE K++ ER + EE T + L++E ++L+KD++
Sbjct: 912 LIKTKIQLEA-------KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
+E+ K TE V NL EE L + L T EKK ++E
Sbjct: 965 LAKVEKE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAH 1007
Query: 1066 QLEL-DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSN 1120
Q L DL E + L +LE++ DD L++E + + + + K +
Sbjct: 1008 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067
Query: 1121 ESEYIFSSEIAEMEDIPSRTE---EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177
ES ++ ++++ + E + K+ + +L ++LQK++ EL+ + +++E++
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Query: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS 1230
+ S+AK E++ ELE S + +E NKK + E ++R+ L
Sbjct: 1128 AER----ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 1231 ------EKSAPEVTAPGAPAYRVLMEQ---LTSVSEELDVRKEEVLILRSQLVSQKEAIQ 1281
E +A + A + L EQ L V ++L+ K E+ + L S E +
Sbjct: 1184 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 1243
Query: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341
K N L + + ++K K E Q I N +A E GE Y
Sbjct: 1244 -KAKGNLEKMCRALEDQLSEIKTKEEEQQRLI-----NDLTAQRARLQTESGE----YSR 1293
Query: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401
L SQL K++ + E L+ ++ EE + + LA LQ +R + L
Sbjct: 1294 QLDEKDTLVSQLSRGKQAFTQQIEELKRQL----EEEIKAKSALAHALQ---SSRHDCDL 1346
Query: 1402 QHEITRLTNE-NLDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDE 1459
E E +L + K + V + + + + A ++ ELE + + Q +E
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
Query: 1460 PIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLI-------PGLPAYI 1512
+ VN LE K+ Q V++L+++++ A + + A
Sbjct: 1407 HVEAVNAK------CASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460
Query: 1513 LFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYS 1572
C L QK L++ + IK ++ D ET+ N + + L +
Sbjct: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520
Query: 1573 GEEGFMKHNTSR 1584
E G H +
Sbjct: 1521 AEGGKRIHELEK 1532
Score = 75.1 bits (183), Expect = 6e-13
Identities = 125/567 (22%), Positives = 235/567 (41%), Gaps = 96/567 (16%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ K+E + ++++ +E + L + ++ KI +LQ +++E +E+ E +
Sbjct: 1084 LKKKEFEMSGLQSK-IEDEQALGMQLQKKIKELQARIEE--------LEEEIEAERASRA 1134
Query: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + +
Sbjct: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194
Query: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAKEMTETME 1057
++HAD + EQ + NL+ L++EK A N V +AK E M
Sbjct: 1195 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMC 1253
Query: 1058 KKLV----------EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPK 1107
+ L EE ++L DL +R R Q E+SR + D L +++
Sbjct: 1254 RALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLS------- 1306
Query: 1108 PGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQ 1167
+ F+ +I E++ E+++ +L LQ + +
Sbjct: 1307 -------------RGKQAFTQQIEELK-------RQLEEEIKAKSALAHALQSSRHDCDL 1346
Query: 1168 EKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKR-QELESENKKLKNELNELR 1226
++ ++E + K E E Q R + E ++++R +ELE KKL L +
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWR-TKYETDAIQRTEELEEAKKKLAQRLQD-- 1403
Query: 1227 KALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDK 1286
+E+ V A A L + L E+++I V + A DK
Sbjct: 1404 ---AEEHVEAVNAKCA--------SLEKTKQRLQNEVEDLMID----VERTNAACAALDK 1448
Query: 1287 NTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQAN 1346
IL E QK ++ A+ KE+ S + N E E LK+ N
Sbjct: 1449 KQRNFDKILAEWKQKCEETH--AELEASQKESRSLSTELFKIKNAYEESLDQLETLKREN 1506
Query: 1347 RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEIT 1406
+ L+ ++ + + E++ +K++ +++ L L+ EASL+HE
Sbjct: 1507 KNLQQEISDLTEQIAEGGKRIH-ELEKIKKQVEQEKSELQAALE-----EAEASLEHEEG 1560
Query: 1407 RLTNENLDLMEQLEKQDKTVRKLKKQL 1433
++ L+L + + D+ + + +++
Sbjct: 1561 KILRIQLELNQVKSEVDRKIAEKDEEI 1587
Score = 59.3 bits (142), Expect = 3e-08
Identities = 86/378 (22%), Positives = 157/378 (41%), Gaps = 75/378 (19%)
Query: 915 VERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS 974
+E K+ + ++ +I L ++ E K + +L ++ E +L++ LE + S
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKIKKQVEQEKSELQAALEEAEAS 1554
Query: 975 EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL------- 1027
E + G++L +Q E+ +++ ++++ +EK +E D+ K+ ++V ++
Sbjct: 1555 LEHEE---GKILRIQLELNQVKSEVDRKIAEK---DEEIDQMKRNHIRIVESMQSTLDAE 1608
Query: 1028 ---KEENTLLKQEKEA--------LNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERL 1076
+ + LK++ E LNH A+ + + + + QL LD + L
Sbjct: 1609 IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLD---DAL 1665
Query: 1077 RYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPGHK-----------RTDSTHSSNE 1121
R Q L E + ER +L EE+ + + K R H+ N
Sbjct: 1666 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1725
Query: 1122 S--------EYIFSSEIAEMEDI--PSRTEEPSEKKVPLDMSLFLK-----------LQK 1160
S E S EMEDI +R E KK D ++ + L++
Sbjct: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
Query: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN 1220
LEQ + +Q LD E+ L+ K+ ++ + R ELE E+ESE K+
Sbjct: 1786 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE------GEVESEQKRNVE 1839
Query: 1221 ELNELRKALSEKSAPEVT 1238
+ LRK E+ E+T
Sbjct: 1840 AVKGLRK--HERKVKELT 1855
Score = 52.4 bits (124), Expect = 4e-06
Identities = 72/338 (21%), Positives = 132/338 (39%), Gaps = 36/338 (10%)
Query: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967
L E RS +L ME + +++ +++ N+ + N + I L
Sbjct: 1605 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDA 1664
Query: 968 LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027
L + +E+ + R LQ EI +LR LEQT +K E+ + + V L
Sbjct: 1665 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLL 1720
Query: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078
+NT L K+ L I Q EM + ++ KK + + + +L E+
Sbjct: 1721 HTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1780
Query: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138
+L LE+ DL+ + + G K+ A + ++
Sbjct: 1781 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ------------IQKLEARVRELEG 1828
Query: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKEE 1191
E ++ V L K +++V EL E K ++ QD +D+ + +V K + E
Sbjct: 1829 EVESEQKRNVEAVKGL-RKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1887
Query: 1192 ERPQIRGAELEYESLKRQELESENKKL---KNELNELR 1226
E + L + ELE ++ ++++N+LR
Sbjct: 1888 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLR 1925
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 585 bits (1508), Expect = e-166
Identities = 460/1515 (30%), Positives = 747/1515 (49%), Gaps = 188/1515 (12%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P + ++ A L ++ G++ ++ +E GK ++ + D K NP
Sbjct: 32 VWVPSDKSGFEPASLKEEV--GEEAIVELVENGKKVKVNKDDIQK-----MNPPKFSKVE 84
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNL+ R+ S LIYTY G+ V INPY+ LPIY E+I+ Y G+
Sbjct: 85 DMAELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKR 143
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS----AS 188
+M PHI+A+ + AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 144 HEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD 203
Query: 189 EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248
+ +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLEKSR
Sbjct: 204 QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
Query: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308
+ QA+EER +HIFY L + A L L + + + G I G D T
Sbjct: 264 AIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL-SNGHVTIPGQQDKDMFQET 322
Query: 309 RQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLMGVD 367
+A ++GI E QMG+ R+++G+L LGN+ F R+ D ++P + L+G++
Sbjct: 323 MEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKV-SHLLGIN 381
Query: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427
+ + ++ + K +K QA A +ALAK Y ++F W+V +N+AL
Sbjct: 382 VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
Query: 428 KQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL 486
+Q SFIG+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E I W
Sbjct: 442 RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
Query: 487 IDF-YDNQPCINLIESKL---GILDLLDEECKMPKGTDDTWAQKL---YNTHLNKCALFE 539
IDF D QPCI+LIE GIL LLDEEC PK TD ++ +K+ TH F+
Sbjct: 502 IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTH----PKFQ 557
Query: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
KP+ L +KA F I H+A KV+Y+ + +L KN D + + +L S K + EL++D ++
Sbjct: 558 KPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
I T L K R G +TVG ++ L LM TL T P++
Sbjct: 618 IIGLDQVAGMSETALPGA----FKTRKGMF-----RTVGQLYKEQLAKLMATLRNTNPNF 668
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQK 717
VRCI PN K D + QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 669 VRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNS 728
Query: 718 --DVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
D KQ C +++ L LD + Y+ G++K+FFRAG +A+LE+ R K+ I Q
Sbjct: 729 IPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQA 788
Query: 776 TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYK 835
RG+L RK + + ++ M K L+R AA + + W+ + + + K
Sbjct: 789 CCRGYLARKAFAKRQQQLTAM-------------KVLQRNCAAYLKLRNWQWWRLFTKVK 835
Query: 836 IRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCC 895
+LQ ++R + +E + V ++++ Q
Sbjct: 836 ------PLLQ------VSRQEEEMMAKEEELVKVREK--------------------QLA 863
Query: 896 FRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKC-LVEKLTNLE 954
+ + E + ++ A ++ ++L Q + ++ + ++ + L K LE
Sbjct: 864 AENRLTEMETLQSQLMAEKLQLQEQL---------QAETELCAEAEELRARLTAKKQELE 914
Query: 955 GIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHAD 1014
I + ++ + ER Q + E K + L+E++ + ++ + EK + A
Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK--VTTEAK 972
Query: 1015 RYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE 1074
K E EQ++ L+++N L +EK+ L RI + +TE EK +K L N
Sbjct: 973 LKKLEEEQII--LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK-----SKSLAKLKNKH 1025
Query: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEM- 1133
+L R E++ +L++ + DST S++ + ++IAE+
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKL---------EGDSTDLSDQIAEL-QAQIAELK 1075
Query: 1134 -------EDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRS 1186
E++ + E+ +M+L K++ ELE + +Q++L+ E+ R+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMAL-----KKIRELESQISELQEDLE--SERASRN 1128
Query: 1187 KAKEEER---PQIRGAELEYE-----SLKRQELESENKKLKNELNELRKALSEKS----- 1233
KA++++R ++ + E E + +QEL S K + E+N L+K L E++
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS---KREQEVNILKKTLEEEAKTHEA 1185
Query: 1234 -APEVTAPGAPAYRVLMEQLTS---VSEELDVRKEEVLILRSQLVSQ-KEAIQPK-DDKN 1287
E+ + A L EQL V L+ K+ + R +L ++ K +Q K D ++
Sbjct: 1186 QIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEH 1245
Query: 1288 TMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANR 1347
L+++Q ++GE + + K T LD N G
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD----NVTG-------------- 1287
Query: 1348 LLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITR 1407
L SQ S+ + AL ++Q +E L E R + SL ++ +
Sbjct: 1288 -LLSQSDSKSSKLTKDFSALESQLQDTQE-------------LLQEENRQKLSLSTKLKQ 1333
Query: 1408 LTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIP 1467
+ +E EQLE++++ L+KQ+ ++ +++ +++ + +E R
Sbjct: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKR----- 1388
Query: 1468 RKEKDFQGMLEYKKE 1482
+ +KD +G+ + +E
Sbjct: 1389 KLQKDLEGLSQRHEE 1403
Score = 87.0 bits (214), Expect = 2e-16
Identities = 120/562 (21%), Positives = 242/562 (43%), Gaps = 63/562 (11%)
Query: 925 MENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS------ETEKLRSDLERLQLSEEEA 978
+E+++ Q + E+N+ L KL +E NS E E+ + +LE+ Q++ A
Sbjct: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK-QIATLHA 1364
Query: 979 KVA---------TGRVLSLQEEIAKLRKDLE--QTRSEKKC-----IEEHADRYKQETEQ 1022
+VA G + + +E KL+KDLE R E+K +E+ R +QE +
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
Query: 1023 LVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQ 1079
L+ +L + L+++++ + + ++ +T+ K EE + E + ++ +
Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEE-----KTISAKYAEERDRAEAEAREKETKAL 1479
Query: 1080 NLLNEFSRLEERYDDL----KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
+L E+ +L K+ T M + S H +S+ ++ EM+
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
E+ + + L + LQ + E++ Q ++ + K++Q++R + E +
Sbjct: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
Query: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLT 1253
+ R++LE + K L+ ++ K E K ++ A R L +
Sbjct: 1600 DERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA 1659
Query: 1254 SVSEELDVRKEEVLILRS---QLVSQKE--AIQPKDDKNTMTDSTILLEDVQKMKDKGEI 1308
S E L KE L+S +++ +E A + + + L +++ KG +
Sbjct: 1660 SREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGAL 1719
Query: 1309 AQAYIGLKETNRSSA----LDYHELNEDGELWLVYEGLKQANRLLESQLQSQ---KRSHE 1361
A L+E R A L+ E G L+ + LK+AN ++ Q+ + +RSH
Sbjct: 1720 A-----LEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID-QINTDLNLERSHA 1773
Query: 1362 NEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEK 1421
+ E R ++ E N++ ++ Q + E +++ + IT L + L EQL+
Sbjct: 1774 QKNENARQQL----ERQNKELKVKLQEM----EGTVKSKYKASITALEAKIAQLEEQLDN 1825
Query: 1422 QDKTVRKLKKQLKVFAKKIGEL 1443
+ K + KQ++ KK+ ++
Sbjct: 1826 ETKERQAACKQVRRTEKKLKDV 1847
Score = 60.8 bits (146), Expect = 1e-08
Identities = 70/340 (20%), Positives = 146/340 (42%), Gaps = 44/340 (12%)
Query: 903 RELKKLKIEARSVERYKKLHIGMENKI----MQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
R++++++ E + + + + K+ L+ +D NK+ +++L L+
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQ---- 1644
Query: 959 SETEKLRSDLERLQLSEEE----AKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHAD 1014
++ + +L+ + S EE AK ++ S++ E+ +L+++L K+ ++ D
Sbjct: 1645 AQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 1015 RYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETK 1065
E ++N + L +EK L RI Q +E+ E KK +
Sbjct: 1705 ELADE----IANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1760
Query: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Q+ DLN ER Q N +LE + +LK ++ M K +K + +
Sbjct: 1761 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITA--------- 1811
Query: 1126 FSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR 1185
++IA++E+ E E++ Q R TE + + ++Q + +R+ + +
Sbjct: 1812 LEAKIAQLEE--QLDNETKERQAACK-------QVRRTEKKLKDVLLQVDDERRNAEQYK 1862
Query: 1186 SKA-KEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
+A K R + +LE + Q + +KL+ EL +
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELED 1902
Score = 44.3 bits (103), Expect = 0.001
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 895 CFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVD---------EQNKDYKC 945
C R + R ++ +I A++ E KKL ME +++QLQ ++ +Q +D
Sbjct: 1650 CMRELDDTRASRE-EILAQAKENEKKLK-SMEAEMIQLQEELAAAERAKRQAQQERDE-- 1705
Query: 946 LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005
L +++ N G E+ R R+ EEE + G + + + K ++Q ++
Sbjct: 1706 LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTD 1765
Query: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
HA + + +Q L+ +N LK + + + + + K +E K+
Sbjct: 1766 LNLERSHAQKNENARQQ----LERQNKELKVKLQEMEGTVKSKYKASITALEAKIA---- 1817
Query: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDL 1095
QLE L++E Q + R E++ D+
Sbjct: 1818 QLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 41.6 bits (96), Expect = 0.007
Identities = 30/164 (18%), Positives = 78/164 (47%), Gaps = 21/164 (12%)
Query: 877 LARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVE-----RYKKLHIGMENKIMQ 931
L R+H +++ +A R +R+ K+LK++ + +E +YK +E KI Q
Sbjct: 1768 LERSHAQKNENA---------RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQ 1818
Query: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEE 991
L+ ++D + K+ + +++ E ++ + + +++A A+ R+ L+ +
Sbjct: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ 1878
Query: 992 IAKLRKDLEQTRSEKKCIE-------EHADRYKQETEQLVSNLK 1028
+ + ++ ++ + ++ ++ E AD +E L + L+
Sbjct: 1879 LEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/160 (20%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 905 LKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKL 964
LKK ++ + L K +++++ QNK+ K KL +EG S+ +
Sbjct: 1752 LKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV---KLQEMEGTVKSKYKAS 1808
Query: 965 RSDLE-RLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023
+ LE ++ EE+ T + +++ + K L+ + +A++YK + ++
Sbjct: 1809 ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKA 1868
Query: 1024 VSNLKEENTLLKQEKE------ALNHRIVQQAKEMTETME 1057
+ LK+ L++ +E A ++ ++ ++ TET +
Sbjct: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 582 bits (1501), Expect = e-166
Identities = 471/1515 (31%), Positives = 743/1515 (49%), Gaps = 176/1515 (11%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VWIP +++A + ++ GD+V++ E GK + D K NP
Sbjct: 36 VWIPSERHGFEAASIKEER--GDEVMVELAENGKKAMVNKDDIQK-----MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNL+ R+ S LIYTY G+ V INPY+ LPIY E+II Y G+
Sbjct: 89 DMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
+M PHI+A++E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 148 HEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKD 207
Query: 189 ---EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
+E ++L +NPI+ES GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE
Sbjct: 208 HNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305
KSR V QA++ER +HIFYQL + A L L +N+ + G P I G D
Sbjct: 268 KSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIP-IPGQQDKDNF 326
Query: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364
T +A ++G S + + ++++ +L GN+ F R+ D ++ P++ C L+
Sbjct: 327 QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM-PENTVAQKLCHLL 385
Query: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
G++ E + ++ + K +K QA A +ALAK Y +LF W+V +N+AL
Sbjct: 386 GMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALD 445
Query: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483
+Q SFIG+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 446 RTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
Query: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
W IDF D QPCI+LIE + G+L LLDEEC PK TD T+ +KL + F+
Sbjct: 506 WNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQ 564
Query: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
KPR L +KA F I H+A KV+Y+ + +L KN D + + +L S + + EL++D ++
Sbjct: 565 KPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR 624
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
+ T G T A TK K +TVG ++ SL LM TL T P++
Sbjct: 625 IVGLDQVT--GMTETAFGSAYKTK-------KGMFRTVGQLYKESLTKLMATLRNTNPNF 675
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
VRCI PN K D + QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 676 VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735
Query: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
D KQ C+ ++ L LD + Y+ G++KIFFRAG +A+LE+ R K+ I Q
Sbjct: 736 IPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQA 795
Query: 776 TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWR--------- 826
RG+L RK + + ++ + K L+R AA + ++W+
Sbjct: 796 VCRGYLARKAFAKKQQQLSAL-------------KVLQRNCAAYLKLRHWQWWRVFTKVK 842
Query: 827 --MYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884
+ V R+ +++ +L+ + ++ R+H+ ++ +K + +
Sbjct: 843 PLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE--- 899
Query: 885 SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYK 944
+ A+ E + ++ A+ E + LH L+ +V+E+ + +
Sbjct: 900 ------------TELFAEAEEMRARLAAKKQELEEILH--------DLESRVEEEEERNQ 939
Query: 945 CLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRS 1004
L + ++ E+L + Q + E A ++ ++EEI L +
Sbjct: 940 ILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIK 999
Query: 1005 EKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKE-MTETMEKKLVEE 1063
EKK +E DR + + QL ++E++A N ++ +E M +E++L +E
Sbjct: 1000 EKKLME---DRIAECSSQLA----------EEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046
Query: 1064 TK-QLELDLNDERL--RYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTD--STHS 1118
K + EL+ +L +L ++ + L+ + D+LK ++ + R D + H
Sbjct: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
Query: 1119 SNESEYI--FSSEIAEM-EDIPSR--------------TEEPSEKKVPLDMSLFLKL--- 1158
+N + + ++IAE+ ED S +EE K L+ +L
Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
Query: 1159 ---QKRVTELEQEKQVMQDELDRKEEQV-----LRSKAKEEERPQIRGAELEYESLK--R 1208
KR E+ + K+ +++E E Q+ + A EE Q+ A+ +L+ +
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
Query: 1209 QELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
Q LE++NK+L E+ L++ +E ++L + +EL + E
Sbjct: 1227 QGLETDNKELACEVKVLQQVKAESEHKR-------------KKLDAQVQELHAKVSEGDR 1273
Query: 1269 LRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQK---------------MKDKGEIAQAYI 1313
LR +L + +Q N + + + LLE+ +K ++D E+ Q
Sbjct: 1274 LRVELAEKASKLQ-----NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1328
Query: 1314 GLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ---LQSQKRSHENEAEALRGE 1370
K N SS + E E L E ++A + LE Q LQSQ + + + G
Sbjct: 1329 RQK-LNLSSRIRQLE-EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
Query: 1371 IQSLKEENN---RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVR 1427
I+SL+E + + L+Q L+ +A L+ RL E DL L+ Q +
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLE--EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
Query: 1428 KLKKQLKVFAKKIGE 1442
L+K+ K F + + E
Sbjct: 1445 NLEKKQKKFDQLLAE 1459
Score = 85.1 bits (209), Expect = 6e-16
Identities = 131/620 (21%), Positives = 264/620 (42%), Gaps = 93/620 (15%)
Query: 897 RRMMAKRELKKLKIEARSVERYKK------LHIGMENKIMQLQRKVDEQN---------- 940
+++ A+ E K+ K++A+ E + K L + + K +LQ ++D +
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 941 ----KDYKCLVEKLTNLEGIYNSET-------------EKLRSDLERLQLSEEEA-KVAT 982
KD L +L + + + ET E+ ++ L+ Q EEEA K
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
Query: 983 GRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALN 1042
+VL+LQ ++A +K ++ + +EE + ++ E L L EE L + E
Sbjct: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL-EEKALAYDKLEKTK 1422
Query: 1043 HRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLM 1102
+R+ Q+ ++T ++ + +Q+ +L ++ ++ LL E + RY + ++
Sbjct: 1423 NRLQQELDDLTVDLDHQ-----RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE 1477
Query: 1103 VHVPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK 1157
+ ++ + E E A+MED+ S ++ + L+ S
Sbjct: 1478 AREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK-RA 1536
Query: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKK 1217
L+++V E+ + + ++DEL E+ LR E Q A+ E + R E E K+
Sbjct: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRL----EVNMQAMKAQFERDLQTRDEQNEEKKR 1592
Query: 1218 LK-NELNELRKALSEKSAPEVTAPGAPA-YRVLMEQLTSVSEELDVRKEEVLILRSQLVS 1275
L ++ EL L ++ A + + ++ L + E + ++EV+ +L +
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
Query: 1276 QKEAIQPKDDKNTMTDSTILL---EDVQKMKD-KGEIAQAYIGLKETNRSSALDYHELNE 1331
Q + Q + ++ + I E +K+K + EI Q L + R+ E +E
Sbjct: 1653 QMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDE 1712
Query: 1332 ---------DGELWLVYEGLKQANRL--LESQLQSQKRSHEN----------EAEALRGE 1370
G+ L+ E + R+ LE +L+ ++ + E + + L E
Sbjct: 1713 LADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 1371 I----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEK 1421
+ + ++ +N +QQL QN +L E +++ + I+ L + L EQLE+
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 1422 Q-------DKTVRKLKKQLK 1434
+ +K VR+ +K+LK
Sbjct: 1833 EAKERAAANKLVRRTEKKLK 1852
Score = 83.6 bits (205), Expect = 2e-15
Identities = 145/626 (23%), Positives = 264/626 (42%), Gaps = 98/626 (15%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
M +R L+ + +E+ K+ +E ++ ++ NK+ C V+ L ++ +
Sbjct: 1197 MRQRHATALEELSEQLEQAKRFKANLEKN----KQGLETDNKELACEVKVLQQVK----A 1248
Query: 960 ETEKLRSDLERLQLSEEEAKVATGRVL--SLQEEIAKLRKDLEQT-----RSEKKCIEEH 1012
E+E R L+ Q+ E AKV+ G L L E+ +KL+ +L+ +EKK I+
Sbjct: 1249 ESEHKRKKLDA-QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 1013 ADRYK-----QETEQLVS-------NL--------KEENTLLKQEKE------------- 1039
D Q+T++L+ NL +E+N+L +Q++E
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 1040 ALNHRIVQQAK---------EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090
AL ++ K E E +KKL+++ + L L ++ L Y L +RL++
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427
Query: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150
DDL ++ V K+ E S+ AE D R E + +K
Sbjct: 1428 ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKETK 1484
Query: 1151 DMSLFLKLQKRVTELE----QEKQV---MQDELDRKEEQVLR----SKAKEEERPQIRGA 1199
+SL L++ + E Q KQ+ M+D + K++ K+K Q+
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
Query: 1200 ELEYESLKRQELESENKKLKNELN-ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE 1258
+ E L+ + +E+ KL+ E+N + KA E+ R+L++Q+ + E
Sbjct: 1545 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604
Query: 1259 L-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEI-AQAYIGLK 1316
L D RK+ L + S+ +K I KD + + + ++V K K + + Y
Sbjct: 1605 LEDERKQRALAVASK---KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
Query: 1317 ETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSH---ENEAEALRGEI-- 1371
E R+S + +++ E L + L+ L+ +L S +R+ E E + L EI
Sbjct: 1662 EEARASRDEIFAQSKESEKKL--KSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 1372 -----QSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLM--------EQ 1418
+L +E R + +AQ + E + L ++ R T +D +
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Query: 1419 LEKQDKTVRKLKKQLKVFAKKIGELE 1444
+K D ++L++Q K K+ ELE
Sbjct: 1780 AQKSDNARQQLERQNKELKAKLQELE 1805
Score = 65.1 bits (157), Expect = 6e-10
Identities = 95/464 (20%), Positives = 198/464 (42%), Gaps = 53/464 (11%)
Query: 935 KVDEQNKDYKCL-----VEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV---- 985
+ + + K+ K L +E+ + + + ++LR+D+E L S+++ +
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534
Query: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045
+L++++ ++R LE+ E + E+ R + + + + + + ++ E +
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 1046 VQQAKEMTETMEKK------LVEETKQLELDLNDERLRYQ-------NLLNEFSRLEERY 1092
++Q +E+ +E + V K++E+DL D + + ++ + +L+ +
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 1093 DDLKEEMTL-------MVHVPKPGHKRTDSTHSS--NESEYIFSSEIAEMEDIPSR---- 1139
D + E+ + K K+ S + E + SSE A R
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 1140 ---TEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDEL----DRKEEQVLRSKAKEEE 1192
T S K LD +L+ R+ +LE+E + Q + DR + L+ E
Sbjct: 1715 DEITNSASGKSALLDEKR--RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 1193 RPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQL 1252
R A + ++ RQ+LE +NK+LK +L EL A+ K ++A A + L EQL
Sbjct: 1773 LAAERSAAQKSDNA-RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ-LEEQL 1830
Query: 1253 TSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ-KMKD-KGEIAQ 1310
++E + L+ R++ ++ +Q +D++ +E +MK K ++ +
Sbjct: 1831 EQEAKERAAANK--LVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEE 1888
Query: 1311 AYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQ 1354
A N S EL++ E EGL + L+++L+
Sbjct: 1889 AEEEATRANASRRKLQRELDDATE---ANEGLSREVSTLKNRLR 1929
Score = 63.5 bits (153), Expect = 2e-09
Identities = 67/341 (19%), Positives = 153/341 (44%), Gaps = 47/341 (13%)
Query: 897 RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956
+R +A KK++I+ + +E + +++++ RK+ Q KDY+
Sbjct: 1611 QRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQ------------ 1658
Query: 957 YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRY 1016
E E+ R+ + + +E++ ++ SL+ EI +L+++L + ++ HA++
Sbjct: 1659 --RELEEARASRDEIFAQSKESE---KKLKSLEAEILQLQEELASSERARR----HAEQE 1709
Query: 1017 KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQL 1067
+ E ++N + L EK L RI Q +E+ E +K + L
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 1068 ELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFS 1127
+L ER Q N +LE + +LK ++ + K K T S
Sbjct: 1770 NAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISA---------LE 1820
Query: 1128 SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSK 1187
++I ++E+ + E+ ++++ + L + +K++ E+ + + + D+ +EQ+ ++
Sbjct: 1821 AKIGQLEE---QLEQEAKERAAAN-KLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKAN 1876
Query: 1188 AKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKA 1228
A+ ++ + +LE + + +KL+ EL++ +A
Sbjct: 1877 ARMKQLKR----QLEEAEEEATRANASRRKLQRELDDATEA 1913
Score = 34.3 bits (77), Expect = 1.2
Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 18/121 (14%)
Query: 1342 LKQANRLLESQLQSQKRSHENE-------AEALRGEIQSLKEENNRQQQLLAQNLQLPP- 1393
+K+ +E +L+ +R H+ AE L+ E + E + +L A+ +L
Sbjct: 864 VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEI 923
Query: 1394 ----EARIEAS------LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGEL 1443
E+R+E LQ+E ++ DL EQL++++ +KL+ + KI ++
Sbjct: 924 LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKM 983
Query: 1444 E 1444
E
Sbjct: 984 E 984
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 582 bits (1501), Expect = e-166
Identities = 381/1044 (36%), Positives = 548/1044 (52%), Gaps = 105/1044 (10%)
Query: 44 EGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYC 103
+ +D E+ + P+ +P + G D+ L L+E +L NL +R+ D LIYTY
Sbjct: 40 DDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH-LIYTYT 98
Query: 104 GIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSG 163
G +LVA+NPY+ L IY + I Y+ + +G+M PHIFA+A+ Y M R+ R+Q I+SG
Sbjct: 99 GSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISG 158
Query: 164 ESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKY 223
ESGAGKT S K +++ A +SG S +E++VL + PI+E+ GNAKT RNDNSSRFGKY
Sbjct: 159 ESGAGKTESTKLILQFLAAISGQHSW--IEQQVLEATPILEAFGNAKTIRNDNSSRFGKY 216
Query: 224 IEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNAD 283
I+I F+KR I GA + YLLEKSRV QA +ERNYH+FY + + K L LG A
Sbjct: 217 IDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQAS 276
Query: 284 NFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSR 343
++NY G EG D++E A+ R A +L +++ I ++LA ILHLGN+ + +R
Sbjct: 277 DYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEAR 336
Query: 344 ---DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNAR 400
+ D+C + L L+ V+ ++ L R L T ET P+S+ QA + R
Sbjct: 337 TFENLDACEV-LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVR 395
Query: 401 DALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVLDIYGFETFEINSFEQFCIN 455
DA K IY +LF WIVD +N A++ Q IG+LDI+GFE F +NSFEQ CIN
Sbjct: 396 DAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCIN 455
Query: 456 YANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECK 514
+ANE LQQ F HVFKLEQEEY E I W I+F DNQ +++I +K + I+ L+DEE K
Sbjct: 456 FANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESK 515
Query: 515 MPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFE 574
PKGTD T KL + H F I HFA V Y+ +GFLEKN+DT+
Sbjct: 516 FPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
Query: 575 EQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKT 634
+ I+++ SS+ K + ++FQ D + G R+P T
Sbjct: 576 DIIQLVHSSRNKFIKQIFQAD---------VAMGAETRKRSP-----------------T 609
Query: 635 VGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISA 694
+ QF+ SL LLM TL A P +VRCIKPN+FK P FD V+QLR G++ETIRI
Sbjct: 610 LSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
Query: 695 AGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFR 751
AG+P R+++ EF RYRVL+ K D + TC+ + E ++ D +Q GKTKIF +
Sbjct: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
Query: 752 AGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKF 811
LE R + I +QK IRG+ R +L+++ AA
Sbjct: 730 DHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAA------------------ 771
Query: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
T+IQ++WR + R+ Y + R + LQ+ R +YR L + + Q
Sbjct: 772 -------TLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR--LARQRIIQFQA 822
Query: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
R R +L R ++ + A++ +Q R M+A+R ++L+ E +K+ + E
Sbjct: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEE----- 877
Query: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL-QLSEEEAKVATGRVLSLQE 990
EKL ++ E R ERL QL+ E+A+ R L +E
Sbjct: 878 ----------------EKLRKEMSAKKAKEEAERKHQERLAQLAREDAE----RELKEKE 917
Query: 991 EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAK 1050
+ ++ LEQ + H+D +++ L L QE +A
Sbjct: 918 AARRKKELLEQMERARHEPVNHSDM----VDKMFGFLGTSGGLPGQEGQA------PSGF 967
Query: 1051 EMTETMEKKLVEETKQLELDLNDE 1074
E E +++VEE L L DE
Sbjct: 968 EDLERGRREMVEEDLDAALPLPDE 991
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 582 bits (1501), Expect = e-166
Identities = 381/1044 (36%), Positives = 548/1044 (52%), Gaps = 105/1044 (10%)
Query: 44 EGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYC 103
+ +D E+ + P+ +P + G D+ L L+E +L NL +R+ D LIYTY
Sbjct: 40 DDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH-LIYTYT 98
Query: 104 GIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSG 163
G +LVA+NPY+ L IY + I Y+ + +G+M PHIFA+A+ Y M R+ R+Q I+SG
Sbjct: 99 GSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISG 158
Query: 164 ESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKY 223
ESGAGKT S K +++ A +SG S +E++VL + PI+E+ GNAKT RNDNSSRFGKY
Sbjct: 159 ESGAGKTESTKLILQFLAAISGQHSW--IEQQVLEATPILEAFGNAKTIRNDNSSRFGKY 216
Query: 224 IEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNAD 283
I+I F+KR I GA + YLLEKSRV QA +ERNYH+FY + + K L LG A
Sbjct: 217 IDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQAS 276
Query: 284 NFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSR 343
++NY G EG D++E A+ R A +L +++ I ++LA ILHLGN+ + +R
Sbjct: 277 DYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEAR 336
Query: 344 ---DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNAR 400
+ D+C + L L+ V+ ++ L R L T ET P+S+ QA + R
Sbjct: 337 TFENLDACEV-LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVR 395
Query: 401 DALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVLDIYGFETFEINSFEQFCIN 455
DA K IY +LF WIVD +N A++ Q IG+LDI+GFE F +NSFEQ CIN
Sbjct: 396 DAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCIN 455
Query: 456 YANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECK 514
+ANE LQQ F HVFKLEQEEY E I W I+F DNQ +++I +K + I+ L+DEE K
Sbjct: 456 FANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESK 515
Query: 515 MPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFE 574
PKGTD T KL + H F I HFA V Y+ +GFLEKN+DT+
Sbjct: 516 FPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
Query: 575 EQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKT 634
+ I+++ SS+ K + ++FQ D + G R+P T
Sbjct: 576 DIIQLVHSSRNKFIKQIFQAD---------VAMGAETRKRSP-----------------T 609
Query: 635 VGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISA 694
+ QF+ SL LLM TL A P +VRCIKPN+FK P FD V+QLR G++ETIRI
Sbjct: 610 LSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
Query: 695 AGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFR 751
AG+P R+++ EF RYRVL+ K D + TC+ + E ++ D +Q GKTKIF +
Sbjct: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
Query: 752 AGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKF 811
LE R + I +QK IRG+ R +L+++ AA
Sbjct: 730 DHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAA------------------ 771
Query: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
T+IQ++WR + R+ Y + R + LQ+ R +YR L + + Q
Sbjct: 772 -------TLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR--LARQRIIQFQA 822
Query: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
R R +L R ++ + A++ +Q R M+A+R ++L+ E +K+ + E
Sbjct: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEE----- 877
Query: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL-QLSEEEAKVATGRVLSLQE 990
EKL ++ E R ERL QL+ E+A+ R L +E
Sbjct: 878 ----------------EKLRKEMSAKKAKEEAERKHQERLAQLAREDAE----RELKEKE 917
Query: 991 EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAK 1050
+ ++ LEQ + H+D +++ L L QE +A
Sbjct: 918 AARRKKELLEQMERARHEPVNHSDM----VDKMFGFLGTSGGLPGQEGQA------PSGF 967
Query: 1051 EMTETMEKKLVEETKQLELDLNDE 1074
E E +++VEE L L DE
Sbjct: 968 EDLERGRREMVEEDLDAALPLPDE 991
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 582 bits (1501), Expect = e-166
Identities = 381/1044 (36%), Positives = 548/1044 (52%), Gaps = 105/1044 (10%)
Query: 44 EGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYC 103
+ +D E+ + P+ +P + G D+ L L+E +L NL +R+ D LIYTY
Sbjct: 40 DDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH-LIYTYT 98
Query: 104 GIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSG 163
G +LVA+NPY+ L IY + I Y+ + +G+M PHIFA+A+ Y M R+ R+Q I+SG
Sbjct: 99 GSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISG 158
Query: 164 ESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKY 223
ESGAGKT S K +++ A +SG S +E++VL + PI+E+ GNAKT RNDNSSRFGKY
Sbjct: 159 ESGAGKTESTKLILQFLAAISGQHSW--IEQQVLEATPILEAFGNAKTIRNDNSSRFGKY 216
Query: 224 IEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNAD 283
I+I F+KR I GA + YLLEKSRV QA +ERNYH+FY + + K L LG A
Sbjct: 217 IDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQAS 276
Query: 284 NFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSR 343
++NY G EG D++E A+ R A +L +++ I ++LA ILHLGN+ + +R
Sbjct: 277 DYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEAR 336
Query: 344 ---DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNAR 400
+ D+C + L L+ V+ ++ L R L T ET P+S+ QA + R
Sbjct: 337 TFENLDACEV-LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVR 395
Query: 401 DALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVLDIYGFETFEINSFEQFCIN 455
DA K IY +LF WIVD +N A++ Q IG+LDI+GFE F +NSFEQ CIN
Sbjct: 396 DAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCIN 455
Query: 456 YANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECK 514
+ANE LQQ F HVFKLEQEEY E I W I+F DNQ +++I +K + I+ L+DEE K
Sbjct: 456 FANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESK 515
Query: 515 MPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFE 574
PKGTD T KL + H F I HFA V Y+ +GFLEKN+DT+
Sbjct: 516 FPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
Query: 575 EQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKT 634
+ I+++ SS+ K + ++FQ D + G R+P T
Sbjct: 576 DIIQLVHSSRNKFIKQIFQAD---------VAMGAETRKRSP-----------------T 609
Query: 635 VGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISA 694
+ QF+ SL LLM TL A P +VRCIKPN+FK P FD V+QLR G++ETIRI
Sbjct: 610 LSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
Query: 695 AGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFR 751
AG+P R+++ EF RYRVL+ K D + TC+ + E ++ D +Q GKTKIF +
Sbjct: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
Query: 752 AGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKF 811
LE R + I +QK IRG+ R +L+++ AA
Sbjct: 730 DHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAA------------------ 771
Query: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
T+IQ++WR + R+ Y + R + LQ+ R +YR L + + Q
Sbjct: 772 -------TLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR--LARQRIIQFQA 822
Query: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
R R +L R ++ + A++ +Q R M+A+R ++L+ E +K+ + E
Sbjct: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEE----- 877
Query: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL-QLSEEEAKVATGRVLSLQE 990
EKL ++ E R ERL QL+ E+A+ R L +E
Sbjct: 878 ----------------EKLRKEMSAKKAKEEAERKHQERLAQLAREDAE----RELKEKE 917
Query: 991 EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAK 1050
+ ++ LEQ + H+D +++ L L QE +A
Sbjct: 918 AARRKKELLEQMERARHEPVNHSDM----VDKMFGFLGTSGGLPGQEGQA------PSGF 967
Query: 1051 EMTETMEKKLVEETKQLELDLNDE 1074
E E +++VEE L L DE
Sbjct: 968 EDLERGRREMVEEDLDAALPLPDE 991
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 572 bits (1474), Expect = e-162
Identities = 335/872 (38%), Positives = 501/872 (57%), Gaps = 35/872 (4%)
Query: 27 LLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVL 86
++K+ KPG +L+ +EGK E+ + + + +P+ + G +D+ L L+E ++
Sbjct: 27 IIKEAKPGK--VLVEDDEGK--EHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMV 82
Query: 87 HNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEA 146
HNL +R+ K IYTY G +LVA+NP++ LP+Y + + Y ++MG++ PH+FA+A
Sbjct: 83 HNLLIRYQQHK-IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNC 141
Query: 147 YKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESI 206
Y M R++R+Q I+SGESGAGKT + K +++ AT+SG S +E++VL +NPI+E+
Sbjct: 142 YFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW--IEQQVLEANPILEAF 199
Query: 207 GNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLC 266
GNAKT RNDNSSRFGKYI+I F+ I GA + +LLEKSRV QA EERNYHIFY +
Sbjct: 200 GNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCML 259
Query: 267 ASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIF 326
+ ++L LG ++Y G EG++DAK+ AH R A +L S+S +
Sbjct: 260 MGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVI 319
Query: 327 RILAGILHLGNVGFTSR-----DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLA 381
++LA ILHLGNVGF + DA P + L+ V ++E+ L +
Sbjct: 320 KLLAAILHLGNVGFMASVFENLDASDVMETPAFPTV---MKLLEVQHQELRDCLIKHTIL 376
Query: 382 TATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVL 436
E + ++ QA + RDA K IY LF WIV +N A+ + Q IG+L
Sbjct: 377 IRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLL 436
Query: 437 DIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCI 496
DI+GFE FE NSFEQ CIN+ANE LQQ F HVF +EQEEY E I W I + DN+P +
Sbjct: 437 DIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTL 496
Query: 497 NLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFAD 555
+L+ K + I+ LLDEE + P+GTD T QKL + H N A + + + F I HFA
Sbjct: 497 DLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAG 556
Query: 556 KVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRT 615
+V YQ EGFLEKN+D + + + ++ SSK K L E+F + + T G + +
Sbjct: 557 EVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE------LAETKLGHGTIRQA 610
Query: 616 PAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEK 675
A + + + T+G QF+ SL LM+ L P+++RCIKPN++K P FD +
Sbjct: 611 KAGNHLFKSAD-SNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRE 669
Query: 676 RAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLE 732
++QLR G++ET+ I +GFP R+T++EF R+ VL+ + + +Q + +
Sbjct: 670 LCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITD 729
Query: 733 KLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKA 792
+ ++ GKTKIF R Q LE R+ L A + IQK +RG+ RK++LR R+A
Sbjct: 730 VWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRA 789
Query: 793 AITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFL 852
A+T+Q + RGY R K + +Q R + R+Y+ R T+ LQ+ RG+L
Sbjct: 790 AVTLQAWWRGYCNRRNFKLI--LVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYL 847
Query: 853 ARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884
R + + + V+IQ RG AR ++++
Sbjct: 848 VRQQVQ--AKRRAVVVIQAHARGMAARRNFQQ 877
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 564 bits (1453), Expect = e-160
Identities = 463/1570 (29%), Positives = 748/1570 (47%), Gaps = 214/1570 (13%)
Query: 12 RVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGE 71
+ WIPD E + AE+ G +++ +G+ L K ++ + P+ + E
Sbjct: 53 KCWIPDGENAYIEAEVKGSEDDG--TVIVETADGESLSI----KEDKIQQMNPPEFEMIE 106
Query: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131
D+ L++L+E +VLH L+ R+ +IYTY G+ V INPY+ LP+Y ++++ AY G+
Sbjct: 107 -DMAMLTHLNEASVLHTLKRRY-GQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKR 164
Query: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS--- 188
+ PHIFAVA A++ M + NQSI+ +GESGAGKTV++K+ ++YFAT++
Sbjct: 165 RSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRK 224
Query: 189 -EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKS 247
+ +E++++ +N I+E+ GNAKT RNDNSSRFGK+I + F R + ++ YLLEKS
Sbjct: 225 KQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKS 284
Query: 248 RVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAH 307
RV+FQ ERNYHIFYQ+ + K +L N +F++ G + +E +DDA+E+
Sbjct: 285 RVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLA 343
Query: 308 TRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVD 367
T QA +LG + G +++ I+H GN+ F + + E LMG++
Sbjct: 344 TEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGIN 403
Query: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427
E+ L H ++ E + + Q T A AL+K +Y ++F W+V +N+AL + +
Sbjct: 404 SSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKL 463
Query: 428 KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLI 487
+ FIG+LDI GFE E NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W I
Sbjct: 464 SRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523
Query: 488 DF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNK 546
F D Q CI+LIE +GIL +L+EEC PK TD T+ KL++ H K +KP+ K
Sbjct: 524 GFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK 583
Query: 547 A----FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPT 602
F + H+A V Y G+LEKNKD + E + V + S ++L LF E +S
Sbjct: 584 KFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF---ENYMSTD 640
Query: 603 SATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIK 662
SA G K KG Q TV + +L+ LM L +T PH+VRCI
Sbjct: 641 SAIPFGE-------KKRKKGASFQ-------TVASLHKENLNKLMTNLKSTAPHFVRCIN 686
Query: 663 PNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ---KDV 719
PN K P D +QQLR GVLE RI GFP+R Y +F RY +L + K
Sbjct: 687 PNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSK 746
Query: 720 LSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRG 779
++ + +L L +D +Y+FG TK+FF+AG + LE +R ++L Q +G
Sbjct: 747 FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQG 806
Query: 780 WLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKI 836
L+R +K L R A I +Q +R + A K ++ ++++ + + ++
Sbjct: 807 KLMRIKFQKILEERDALILIQWNIRAFMA---------VKNWPWMRLFFKIKPLVKSSEV 857
Query: 837 RRAATIVLQ--SYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQC 894
+ + + L+ L ++ +++ + K V + + + + ++ A + QC
Sbjct: 858 GEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQC 917
Query: 895 CFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLE 954
E K I +E ++ +L +V+E+ + L + LE
Sbjct: 918 ---------------------EWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLE 956
Query: 955 GIYNSETEKLRSDLERLQL----SEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010
E +L+ +++ L+ SE+E + +V +L EE+ L +D+ + K ++
Sbjct: 957 ----DECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQ 1012
Query: 1011 E----HADRYKQETEQLVS----NLKEENTL------LKQEKEAL------------NHR 1044
E D E E+L S NLK E + L+QE++A N +
Sbjct: 1013 EAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLK 1072
Query: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN-------LLNEFSRLEERYDDLKE 1097
+ +++ E E+ ++ L EE ++ EL+L+ + +N L L+ + DLKE
Sbjct: 1073 LNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKE 1132
Query: 1098 ----EMTLMVHVPKPGHKRTDSTHSSNES-EYIFSSEIAEMEDIPSRTEEPSEKKVPLDM 1152
E T + + T NE E + S +A++E ++ +E +K+ DM
Sbjct: 1133 KLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLE--ITKKQETKFQKLHRDM 1190
Query: 1153 ----------SLFLK---------LQKRVTELEQEKQVMQ----------DELDRKEEQV 1183
S LK L+ +V L+Q KQ ++ D+L + EQ+
Sbjct: 1191 EEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQM 1250
Query: 1184 LRSKAKE-------EERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSA-- 1234
R+KA EER A+L+ + +L ++ KL +E E + L EK A
Sbjct: 1251 TRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALI 1310
Query: 1235 ----------------------PEVTAPGAPAYRVLMEQ-----LTSVSEELDVRKEEVL 1267
E + A A+ + Q L EE K E+
Sbjct: 1311 NQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELH 1370
Query: 1268 ILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQK-----MKDKGEIAQAYIGLKETNRSS 1322
S++ ++ + K + N + T LED +K +++ E A + +
Sbjct: 1371 RTLSKVNAEMVQWRMKYENNVI-QRTEDLEDAKKELAIRLQEAAE-AMGVANARNASLER 1428
Query: 1323 ALDYHELNEDGELWLVYEGLKQANRLLESQLQS------QKRSHENE---AEALRGEIQS 1373
A +L L + + A RL + QLQS K+ HE +A + E+Q+
Sbjct: 1429 ARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQA 1488
Query: 1374 LKEE-----NNRQQQLLAQNLQLPPEARIEASLQHEITRLTN---ENLDLMEQLEKQDKT 1425
L E N ++ ++ Q R +LQ EI+ LTN E + ++EK K
Sbjct: 1489 LSTELLKLKNTYEESIVGQETL----RRENKNLQEEISNLTNQVREGTKNLTEMEKVKKL 1544
Query: 1426 VRKLKKQLKV 1435
+ + K +++V
Sbjct: 1545 IEEEKTEVQV 1554
Score = 70.1 bits (170), Expect = 2e-11
Identities = 121/556 (21%), Positives = 231/556 (41%), Gaps = 97/556 (17%)
Query: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985
EN ++Q +++ K+ +++ G+ N+ L +LQL +A G+V
Sbjct: 1388 ENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKV 1447
Query: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045
S A R D +Q +S K + +KQ+ E+ + L ++E +AL+ +
Sbjct: 1448 RS-----AAARLDQKQLQSGKALAD-----WKQKHEESQALLDAS----QKEVQALSTEL 1493
Query: 1046 VQQAKEMTETMEKKLV-EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
++ + T E+ +V +ET + E +NL E S L + + + +T M
Sbjct: 1494 LK----LKNTYEESIVGQETLRRE---------NKNLQEEISNLTNQVREGTKNLTEMEK 1540
Query: 1105 VPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
V K + E E++ TE E+ + L+L + E
Sbjct: 1541 VKK-----------------LIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583
Query: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
LE++ L K+E++ + K++ + L+ E+ R E+ KK++ +LNE
Sbjct: 1584 LERK-------LSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNE 1636
Query: 1225 LRKALS--EKSAPEVT-APGAPAYRV--LMEQL-------TSVSEELDVRKEEVLILRSQ 1272
+ LS + E T + G ++ L QL + + E++ V + +L+S+
Sbjct: 1637 MELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSE 1696
Query: 1273 L---------------VSQKEAIQPKDDKNTM-TDSTILLEDVQKM--------KDKGEI 1308
L +S++E ++ + N T +T LL +K+ K+ E+
Sbjct: 1697 LEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEV 1756
Query: 1309 AQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQS----QKRSHENEA 1364
Q +E + +A++ L+E EL + + R E+ Q+ QKR E E
Sbjct: 1757 VQECQNAEEKAKKAAIEAANLSE--ELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQ 1814
Query: 1365 EALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDK 1424
AL G + +++ +R ++L +L E R A Q RL +L Q E+ K
Sbjct: 1815 MALMGSRKQIQKLESRVRELEG---ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKK 1871
Query: 1425 TVRKLKKQLKVFAKKI 1440
+ +++ Q+ K+
Sbjct: 1872 NLSRMQTQMDKLQLKV 1887
Score = 63.2 bits (152), Expect = 2e-09
Identities = 120/599 (20%), Positives = 241/599 (40%), Gaps = 70/599 (11%)
Query: 868 IIQKRVRGWLARTHYKRSMH---AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIG 924
+ Q R +G L R +++ + A+I +Q R MA + +++ + K +G
Sbjct: 799 LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVG 858
Query: 925 MENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGR 984
E++ L+ E +L+ LE+ + EE K +
Sbjct: 859 -----------------------EEVAGLK----EECAQLQKALEKSEFQREELKA---K 888
Query: 985 VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
+SL +E L L+ + +EE + + QL + +KE + +++E+E +
Sbjct: 889 QVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSEL 948
Query: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLM-- 1102
+ K E E K +E LE L + ++ L E + L E+++ +
Sbjct: 949 TARGRKLEDECFELK--KEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNR 1006
Query: 1103 -VHVPKPGHKRT-DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK 1160
V + H++T D H E S ++E E E++ M+ +L K
Sbjct: 1007 AAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHK 1066
Query: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN 1220
L+ ++ M++ L+ + + K+E +++E E +L+ K+L+
Sbjct: 1067 LEGNLKLNRESMEN-LESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQT 1125
Query: 1221 ELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAI 1280
++ +L++ L + A LT +L+ R EEV ++Q E
Sbjct: 1126 QIKDLKEKLEAERTTRAKMERERA------DLTQDLADLNERLEEV---GGSSLAQLEIT 1176
Query: 1281 QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYE 1340
+ ++ K QK+ E A + ET S++L + EL E
Sbjct: 1177 KKQETK------------FQKLHRDMEEATLHF---ETT-SASLKKRHADSLAELEGQVE 1220
Query: 1341 GLKQANRLLE---SQLQSQKRSHENEAEAL-RGEIQSLKEENNRQQQLLAQNLQLPPEAR 1396
L+Q + LE S LQ + E + R + + K +++L +L +
Sbjct: 1221 NLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQ 1280
Query: 1397 IEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ 1455
+ L + T+L +E+ + + +LE+++ + +L ++ F ++I +L GQ+E + Q
Sbjct: 1281 LANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLR-GQLEKETKSQ 1338
Score = 53.9 bits (128), Expect = 1e-06
Identities = 111/634 (17%), Positives = 249/634 (39%), Gaps = 74/634 (11%)
Query: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
+ KR L VE +++ +E LQ +VD+ + + N E +
Sbjct: 1204 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTL 1263
Query: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
E+L +L + A + L E + + LE+ + + + ++
Sbjct: 1264 YEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQ 1323
Query: 1020 TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK----------QLEL 1069
E L L++E + + AL H + Q+A+ + + ++ EE + ++
Sbjct: 1324 IEDLRGQLEKET----KSQSALAHAL-QKAQRDCDLLREQYEEEQEVKAELHRTLSKVNA 1378
Query: 1070 DLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSS-----NESEY 1124
++ R++Y+N N R E+ +D K+E+ + + ++ ++S ++ +
Sbjct: 1379 EMVQWRMKYEN--NVIQRTED-LEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435
Query: 1125 IFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL 1184
++++ + S +K+ L+ K + + +Q+ + Q LD +++V
Sbjct: 1436 ELGDALSDLGKVRSAAARLDQKQ--------LQSGKALADWKQKHEESQALLDASQKEV- 1486
Query: 1185 RSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSE--KSAPEVTAPGA 1242
+A E +++ E + ++ L ENK L+ E++ L + E K+ E+
Sbjct: 1487 --QALSTELLKLKNT-YEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEM----E 1539
Query: 1243 PAYRVLMEQLTSVSEELD-----VRKEEVLILRSQL--------VSQKEAIQPKDDKNTM 1289
+++ E+ T V L+ + + E IL QL + +K + + ++ +N
Sbjct: 1540 KVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFR 1599
Query: 1290 TDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLL 1349
++ +Q D ++ + + L+ EL V E K +L
Sbjct: 1600 RKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQ 1659
Query: 1350 ------------ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARI 1397
+QL S + AE +QS E+ Q+ + +L E +
Sbjct: 1660 IQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELL 1719
Query: 1398 EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQII 1457
EA+ I +N L+ Q +K + V +++K+ + ++ E + +
Sbjct: 1720 EAT--ERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANL 1777
Query: 1458 DEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNL 1491
E + +K++D LE +E+ ++ + +L
Sbjct: 1778 SEEL------KKKQDTIAHLERTRENMEQTITDL 1805
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 542 bits (1397), Expect = e-153
Identities = 467/1489 (31%), Positives = 727/1489 (48%), Gaps = 127/1489 (8%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
Query: 189 ---EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
+E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE
Sbjct: 228 PGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287
Query: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305
KSR + QA++E ++HIFYQL A L L ++ + G P + +
Sbjct: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSSPGQERELF 345
Query: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364
T ++ +LG S + + R+++ +L GN+ R+ D T+P + C L+
Sbjct: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKL-CRLL 404
Query: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
G+ + L ++ + K +K QA A +ALAK Y +LF W+V +N+AL
Sbjct: 405 GLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD 464
Query: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483
+ +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E IP
Sbjct: 465 RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524
Query: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
WT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+ F+
Sbjct: 525 WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQ 583
Query: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
+PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++ E+++D E
Sbjct: 584 RPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG 643
Query: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
+ +S G P GRP + +TVG ++ SL LM TL+ T P +
Sbjct: 644 IVGLEQVSSLG--------DGPPGGRP---RRGMFRTVGQLYKESLSRLMATLSNTNPSF 692
Query: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
VRCI PN K + + + QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 693 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA 752
Query: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
D KQ C+ +++ L LD + Y+ G++KIFFRAG +A LE+ R K+ + Q
Sbjct: 753 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA 812
Query: 776 TIRGWLLRK---KYLRMRKAAITMQRYVRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR 831
RG+L R+ K + + A MQR Y + R + + TK ++Q + V++
Sbjct: 813 AARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQ 872
Query: 832 -RRYKIRRAATIVLQS-----YLRGFLA-----RNRYRKILREHKAVIIQ-KRVRGWLAR 879
R ++++ + QS L+G +A R R + LR + + + RG LA
Sbjct: 873 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAA 932
Query: 880 THYKRSMHAII--------YLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
K+ + ++ + C R+M + E K+L+ + +E + + G K +Q
Sbjct: 933 R--KQELELVVSELEARVGEEEECSRQM--QTEKKRLQQHIQELEAHLEAEEGARQK-LQ 987
Query: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLE-RL-----QLSEEEAKVATGRV 985
L++ E K E L LE NS+ K R LE RL Q +EEE KV +
Sbjct: 988 LEKVTTEAK--MKKFEEDLLLLED-QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1044
Query: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045
L L+ E A + ++ R E+K +E ++ K+ + S L+E+ +Q E L ++
Sbjct: 1045 LRLKYE-ATIADMEDRLRKEEKGRQE-LEKLKRRLDGESSELQEQMVEQQQRAEELRAQL 1102
Query: 1046 VQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105
++ +E+ + + E + +L ++L + L E +DL+ E
Sbjct: 1103 GRKEEELQAALARAEDEGGARAQL--------LKSLREAQAALAEAQEDLESERVARTKA 1154
Query: 1106 PKPGHKRTDSTHS-SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
K + + E E S A+ E R +E +E K L+ + + V E
Sbjct: 1155 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIH-EAAVQE 1213
Query: 1165 LEQEKQVMQDELDRKEEQVLRSK--------AKEEERPQIRGAELEYESLKRQELESENK 1216
L Q EL + EQ R K A E E ++R AEL RQE E +
Sbjct: 1214 LRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR-AELSSLQTARQEGEQRRR 1272
Query: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQ 1276
+L+ +L E++ + A A + +L +VS L+ + + + L +L S
Sbjct: 1273 RLELQLQEVQGRAGD--GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330
Query: 1277 KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELW 1336
+ L D Q++ + A+ +G +R A++ +L
Sbjct: 1331 EAQ----------------LHDAQELLQEETRAKLALG----SRVRAMEAEAAGLREQLE 1370
Query: 1337 LVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPP 1393
++A R L ++QL +R E EA AL + + R+ + L Q +L
Sbjct: 1371 EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAREAEALTQ--RLAE 1427
Query: 1394 EARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
+ L+ RL E D LE+Q + V L+K+ + F + + E
Sbjct: 1428 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1476
Score = 77.4 bits (189), Expect = 1e-13
Identities = 140/603 (23%), Positives = 243/603 (40%), Gaps = 127/603 (21%)
Query: 959 SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
S TE D + L E AK+A G RV +++ E A LR+ LE E+ E A R
Sbjct: 1328 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1383
Query: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEKKLVEETKQL 1067
Q + +S + EE L+ +EA + Q+ E TET+++ L ++L
Sbjct: 1384 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDR-LERGRRRL 1442
Query: 1068 ELDLNDERL---RYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEY 1124
+ +L+D + + + L++ + + ++D L E V +R ++ E+
Sbjct: 1443 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1502
Query: 1125 IFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK-------------------------LQ 1159
+ + E E E + + ++ L L+
Sbjct: 1503 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1562
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAELEY 1203
+VTELE E +D R E V R +A EE R Q+R AE+E
Sbjct: 1563 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1622
Query: 1204 ESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLMEQL 1252
+ ++Q + KKL+ EL EL+ ++ K ++ A +R + E
Sbjct: 1623 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1682
Query: 1253 TSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI------- 1294
TS E +E EVL L+ +L + A Q + D++ M D
Sbjct: 1683 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1742
Query: 1295 -LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QANRLL 1349
+LE+ ++++ G + Q L+E +S L LN+ +L L E L A R
Sbjct: 1743 AILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAERSF 1796
Query: 1350 ESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQQLL 1385
++ +S ++ E + + LRG I +L+ E ++++L
Sbjct: 1797 SAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERIL 1856
Query: 1386 AQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
+ L E R+ E LQ E R + L +QLEK + V++LK+QL+ ++ +
Sbjct: 1857 SGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEASRAQ 1914
Query: 1445 VGQ 1447
G+
Sbjct: 1915 AGR 1917
Score = 63.5 bits (153), Expect = 2e-09
Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%)
Query: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237
Query: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1296
Query: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1297 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1354
Query: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1355 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1410
Query: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1411 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1470
Query: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1471 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1530
Query: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
L + + KS E+ A L Q+T + +EL ++ L L +
Sbjct: 1531 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1586
Query: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
+A++ + ++ D+Q + GE + L + R + ++ E + L +
Sbjct: 1587 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1633
Query: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395
A + LE +L+ K A A +G+ +++K+ Q Q+ L + ++ +
Sbjct: 1634 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1684
Query: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450
R E Q+ + L E L L E+L D+ R+ ++ A ++ N
Sbjct: 1685 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1738
Query: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485
+S I++E R+ + G LE + E+EQ
Sbjct: 1739 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1766
Score = 53.1 bits (126), Expect = 2e-06
Identities = 83/379 (21%), Positives = 153/379 (40%), Gaps = 72/379 (18%)
Query: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIY 957
R + EL++LK + S + G E + QL++ + + ++ + E T+ E I+
Sbjct: 1636 RKKLEGELEELKAQMASAGQ------GKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1689
Query: 958 NSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
+ E SE+ K VL LQEE+A + Q + ++ +E AD
Sbjct: 1690 SQNRE-----------SEKRLKGLEAEVLRLQEELAASDRARRQAQQDR---DEMADEVA 1735
Query: 1018 QETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE 1074
+ L+E+ L L Q +E L Q E+ +KL+ + + L +L+ E
Sbjct: 1736 NGNLSKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLNDRYRKLLLQVESLTTELSAE 1793
Query: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEME 1134
R + +LE + +L+ + + HK T + S++A+ E
Sbjct: 1794 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA---------LESKLAQAE 1844
Query: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP 1194
+ + E+ + +++ L L + +KR+ E+ V+Q E +R+ LR
Sbjct: 1845 E---QLEQETRERI-LSGKLVRRAEKRLKEV-----VLQVEEERRVADQLRD-------- 1887
Query: 1195 QIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
Q+ L + LKRQ E+E + + + R L +L
Sbjct: 1888 QLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR---------------------LQRELED 1926
Query: 1255 VSEELDVRKEEVLILRSQL 1273
V+E + EV LR++L
Sbjct: 1927 VTESAESMNREVTTLRNRL 1945
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 541 bits (1393), Expect = e-153
Identities = 468/1497 (31%), Positives = 728/1497 (48%), Gaps = 135/1497 (9%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
Query: 187 ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
S +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GA
Sbjct: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
Query: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297
N+ TYLLEKSR + QA++E ++HIFYQL A L L ++ + G P
Sbjct: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
Query: 298 GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356
+ + T ++ +LG S + + R+++ +L GN+ R+ D T+P
Sbjct: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Query: 357 LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416
+ C L+G+ + L ++ + K +K QA A +ALAK Y +LF W+V
Sbjct: 406 QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
Query: 417 DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
+N+AL + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQE
Sbjct: 465 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
Query: 476 EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
EY +E IPWT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+
Sbjct: 525 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
Query: 532 LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
F++PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++
Sbjct: 585 -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
Query: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649
E+++D E + +S G P GRP + +TVG ++ SL LM T
Sbjct: 644 EIWKDVEGIVGLEQVSSLG--------DGPPGGRP---RRGMFRTVGQLYKESLSRLMAT 692
Query: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709
L+ T P +VRCI PN K + + + QLR GVLE IRI GFP+R +QEF R
Sbjct: 693 LSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQR 752
Query: 710 YRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLR 767
Y +L D KQ C+ +++ L LD + Y+ G++KIFFRAG +A LE+ R K+
Sbjct: 753 YEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVT 812
Query: 768 AACIRIQKTIRGWLLRK---KYLRMRKAAITMQRYVRGY-QARCYAKFLRRTKAATIIQK 823
+ Q RG+L R+ K + + A MQR Y + R + + TK ++Q
Sbjct: 813 DIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQV 872
Query: 824 YWRMYVVR-RRYKIRRAATIVLQS-----YLRGFLA-----RNRYRKILREHKAVIIQ-K 871
+ V++ R ++++ + QS L+G +A R R + LR + + +
Sbjct: 873 TRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAE 932
Query: 872 RVRGWLARTHYKRSMHAII--------YLQCCFRRMMAKRELKKLKIEARSVERYKKLHI 923
RG LA K+ + ++ + C R+M + E K+L+ + +E + +
Sbjct: 933 ETRGRLAAR--KQELELVVSELEARVGEEEECSRQM--QTEKKRLQQHIQELEAHLEAEE 988
Query: 924 GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLE-RL-----QLSEEE 977
G K +QL++ E K E L LE NS+ K R LE RL Q +EEE
Sbjct: 989 GARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QNSKLSKERKLLEDRLAEFSSQAAEEE 1044
Query: 978 AKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQE 1037
KV + L L+ E A + ++ R E+K +E ++ K+ + S L+E+ +Q
Sbjct: 1045 EKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE-LEKLKRRLDGESSELQEQMVEQQQR 1102
Query: 1038 KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKE 1097
E L ++ ++ +E+ + + E + +L ++L + L E +DL+
Sbjct: 1103 AEELRAQLGRKEEELQAALARAEDEGGARAQL--------LKSLREAQAALAEAQEDLES 1154
Query: 1098 EMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFL 1156
E K + + E E S A+ E R +E +E K L+ +
Sbjct: 1155 ERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
Query: 1157 KLQKRVTELEQEKQVMQDELDRKEEQVLRSK--------AKEEERPQIRGAELEYESLKR 1208
+ V EL Q EL + EQ R K A E E ++R AEL R
Sbjct: 1215 H-EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR-AELSSLQTAR 1272
Query: 1209 QELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
QE E ++L+ +L E++ + A A + +L +VS L+ + + +
Sbjct: 1273 QEGEQRRRRLELQLQEVQGRAGD--GERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1330
Query: 1269 LRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHE 1328
L +L S + L D Q++ + A+ +G +R A++
Sbjct: 1331 LSKELSSTEAQ----------------LHDAQELLQEETRAKLALG----SRVRAMEAEA 1370
Query: 1329 LNEDGELWLVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLL 1385
+L ++A R L ++QL +R E EA AL + + R+ + L
Sbjct: 1371 AGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAREAEAL 1429
Query: 1386 AQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Q +L + L+ RL E D LE+Q + V L+K+ + F + + E
Sbjct: 1430 TQ--RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1484
Score = 77.4 bits (189), Expect = 1e-13
Identities = 140/603 (23%), Positives = 243/603 (40%), Gaps = 127/603 (21%)
Query: 959 SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
S TE D + L E AK+A G RV +++ E A LR+ LE E+ E A R
Sbjct: 1336 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1391
Query: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEKKLVEETKQL 1067
Q + +S + EE L+ +EA + Q+ E TET+++ L ++L
Sbjct: 1392 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDR-LERGRRRL 1450
Query: 1068 ELDLNDERL---RYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEY 1124
+ +L+D + + + L++ + + ++D L E V +R ++ E+
Sbjct: 1451 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1510
Query: 1125 IFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK-------------------------LQ 1159
+ + E E E + + ++ L L+
Sbjct: 1511 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1570
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAELEY 1203
+VTELE E +D R E V R +A EE R Q+R AE+E
Sbjct: 1571 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1630
Query: 1204 ESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLMEQL 1252
+ ++Q + KKL+ EL EL+ ++ K ++ A +R + E
Sbjct: 1631 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1690
Query: 1253 TSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI------- 1294
TS E +E EVL L+ +L + A Q + D++ M D
Sbjct: 1691 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1750
Query: 1295 -LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QANRLL 1349
+LE+ ++++ G + Q L+E +S L LN+ +L L E L A R
Sbjct: 1751 AILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAERSF 1804
Query: 1350 ESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQQLL 1385
++ +S ++ E + + LRG I +L+ E ++++L
Sbjct: 1805 SAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERIL 1864
Query: 1386 AQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
+ L E R+ E LQ E R + L +QLEK + V++LK+QL+ ++ +
Sbjct: 1865 SGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEASRAQ 1922
Query: 1445 VGQ 1447
G+
Sbjct: 1923 AGR 1925
Score = 63.5 bits (153), Expect = 2e-09
Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%)
Query: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
Query: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1304
Query: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1305 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
Query: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1363 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1418
Query: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1419 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1478
Query: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1479 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1538
Query: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
L + + KS E+ A L Q+T + +EL ++ L L +
Sbjct: 1539 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1594
Query: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
+A++ + ++ D+Q + GE + L + R + ++ E + L +
Sbjct: 1595 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1641
Query: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395
A + LE +L+ K A A +G+ +++K+ Q Q+ L + ++ +
Sbjct: 1642 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1692
Query: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450
R E Q+ + L E L L E+L D+ R+ ++ A ++ N
Sbjct: 1693 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1746
Query: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485
+S I++E R+ + G LE + E+EQ
Sbjct: 1747 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1774
Score = 53.1 bits (126), Expect = 2e-06
Identities = 83/379 (21%), Positives = 153/379 (40%), Gaps = 72/379 (18%)
Query: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIY 957
R + EL++LK + S + G E + QL++ + + ++ + E T+ E I+
Sbjct: 1644 RKKLEGELEELKAQMASAGQ------GKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1697
Query: 958 NSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
+ E SE+ K VL LQEE+A + Q + ++ +E AD
Sbjct: 1698 SQNRE-----------SEKRLKGLEAEVLRLQEELAASDRARRQAQQDR---DEMADEVA 1743
Query: 1018 QETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE 1074
+ L+E+ L L Q +E L Q E+ +KL+ + + L +L+ E
Sbjct: 1744 NGNLSKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLNDRYRKLLLQVESLTTELSAE 1801
Query: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEME 1134
R + +LE + +L+ + + HK T + S++A+ E
Sbjct: 1802 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA---------LESKLAQAE 1852
Query: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP 1194
+ + E+ + +++ L L + +KR+ E+ V+Q E +R+ LR
Sbjct: 1853 E---QLEQETRERI-LSGKLVRRAEKRLKEV-----VLQVEEERRVADQLRD-------- 1895
Query: 1195 QIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
Q+ L + LKRQ E+E + + + R L +L
Sbjct: 1896 QLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR---------------------LQRELED 1934
Query: 1255 VSEELDVRKEEVLILRSQL 1273
V+E + EV LR++L
Sbjct: 1935 VTESAESMNREVTTLRNRL 1953
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 534 bits (1375), Expect = e-151
Identities = 470/1522 (30%), Positives = 731/1522 (48%), Gaps = 152/1522 (9%)
Query: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
Query: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
Query: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
Query: 187 ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
S +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GA
Sbjct: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
Query: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297
N+ TYLLEKSR + QA++E ++HIFYQL A L L ++ + G P
Sbjct: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
Query: 298 GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356
+ + T ++ +LG S + + R+++ +L GN+ R+ D T+P
Sbjct: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Query: 357 LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416
+ C L+G+ + L ++ + K +K QA A +ALAK Y +LF W+V
Sbjct: 406 QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
Query: 417 DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
+N+AL + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQE
Sbjct: 465 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
Query: 476 EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
EY +E IPWT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+
Sbjct: 525 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
Query: 532 LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
F++PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++
Sbjct: 585 -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
Query: 590 ELFQDD------------------------EKAISPTSATS-SGRTPLTRTPAKPTKGRP 624
E+++D+ AISP G ++ P GRP
Sbjct: 644 EIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRP 703
Query: 625 GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRAC 684
+ +TVG ++ SL LM TL+ T P +VRCI PN K + + + QLR
Sbjct: 704 ---RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCN 760
Query: 685 GVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQ 742
GVLE IRI GFP+R +QEF RY +L D KQ C+ +++ L LD + Y+
Sbjct: 761 GVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYR 820
Query: 743 FGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRY 799
G++KIFFRAG +A LE+ R K+ + Q RG+L R+ K + + A MQR
Sbjct: 821 VGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 880
Query: 800 VRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR-RRYKIRRAATIVLQS-----YLRGFL 852
Y + R + + TK ++Q + V++ R ++++ + QS L+G +
Sbjct: 881 CAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRV 940
Query: 853 A-----RNRYRKILREHKAVIIQ-KRVRGWLARTHYKRSMHAII--------YLQCCFRR 898
A R R + LR + + + RG LA K+ + ++ + C R+
Sbjct: 941 AQLEEERARLAEQLRAEAELCAEAEETRGRLAAR--KQELELVVSELEARVGEEEECSRQ 998
Query: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
M + E K+L+ + +E + + G K +QL++ E K E L LE N
Sbjct: 999 M--QTEKKRLQQHIQELEAHLEAEEGARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QN 1052
Query: 959 SETEKLRSDLE-RL-----QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
S+ K R LE RL Q +EEE KV + L L+ E A + ++ R E+K +E
Sbjct: 1053 SKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE- 1110
Query: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072
++ K+ + S L+E+ +Q E L ++ ++ +E+ + + E + +L
Sbjct: 1111 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL--- 1167
Query: 1073 DERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIA 1131
++L + L E +DL+ E K + + E E S A
Sbjct: 1168 -----LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
Query: 1132 EMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSK---- 1187
+ E R +E +E K L+ + + V EL Q EL + EQ R K
Sbjct: 1223 QQELRSKREQEVTELKKTLEEETRIH-EAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281
Query: 1188 ----AKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP 1243
A E E ++R AEL RQE E ++L+ +L E++ + A A
Sbjct: 1282 KTRLALEAEVSELR-AELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAE 1338
Query: 1244 AYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK 1303
+ +L +VS L+ + + + L +L S + L D Q++
Sbjct: 1339 KLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ----------------LHDAQELL 1382
Query: 1304 DKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLL---ESQLQSQKRSH 1360
+ A+ +G +R A++ +L ++A R L ++QL +R
Sbjct: 1383 QEETRAKLALG----SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1438
Query: 1361 ENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLE 1420
E EA AL + + R+ + L Q +L + L+ RL E D LE
Sbjct: 1439 EEEAGALEAG-EEARRRAAREAEALTQ--RLAEKTETVDRLERGRRRLQQELDDATMDLE 1495
Query: 1421 KQDKTVRKLKKQLKVFAKKIGE 1442
+Q + V L+K+ + F + + E
Sbjct: 1496 QQRQLVSTLEKKQRKFDQLLAE 1517
Score = 77.4 bits (189), Expect = 1e-13
Identities = 140/603 (23%), Positives = 243/603 (40%), Gaps = 127/603 (21%)
Query: 959 SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
S TE D + L E AK+A G RV +++ E A LR+ LE E+ E A R
Sbjct: 1369 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1424
Query: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEKKLVEETKQL 1067
Q + +S + EE L+ +EA + Q+ E TET+++ L ++L
Sbjct: 1425 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDR-LERGRRRL 1483
Query: 1068 ELDLNDERL---RYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEY 1124
+ +L+D + + + L++ + + ++D L E V +R ++ E+
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Query: 1125 IFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK-------------------------LQ 1159
+ + E E E + + ++ L L+
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
Query: 1160 KRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAELEY 1203
+VTELE E +D R E V R +A EE R Q+R AE+E
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Query: 1204 ESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLMEQL 1252
+ ++Q + KKL+ EL EL+ ++ K ++ A +R + E
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
Query: 1253 TSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI------- 1294
TS E +E EVL L+ +L + A Q + D++ M D
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
Query: 1295 -LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QANRLL 1349
+LE+ ++++ G + Q L+E +S L LN+ +L L E L A R
Sbjct: 1784 AILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAERSF 1837
Query: 1350 ESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQQLL 1385
++ +S ++ E + + LRG I +L+ E ++++L
Sbjct: 1838 SAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERIL 1897
Query: 1386 AQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
+ L E R+ E LQ E R + L +QLEK + V++LK+QL+ ++ +
Sbjct: 1898 SGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEASRAQ 1955
Query: 1445 VGQ 1447
G+
Sbjct: 1956 AGR 1958
Score = 63.5 bits (153), Expect = 2e-09
Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%)
Query: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 1219 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1278
Query: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 1279 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1337
Query: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1338 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1395
Query: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1396 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1451
Query: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1452 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1511
Query: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1512 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1571
Query: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
L + + KS E+ A L Q+T + +EL ++ L L +
Sbjct: 1572 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1627
Query: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
+A++ + ++ D+Q + GE + L + R + ++ E + L +
Sbjct: 1628 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1674
Query: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395
A + LE +L+ K A A +G+ +++K+ Q Q+ L + ++ +
Sbjct: 1675 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
Query: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450
R E Q+ + L E L L E+L D+ R+ ++ A ++ N
Sbjct: 1726 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1779
Query: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485
+S I++E R+ + G LE + E+EQ
Sbjct: 1780 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1807
Score = 53.1 bits (126), Expect = 2e-06
Identities = 83/379 (21%), Positives = 153/379 (40%), Gaps = 72/379 (18%)
Query: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIY 957
R + EL++LK + S + G E + QL++ + + ++ + E T+ E I+
Sbjct: 1677 RKKLEGELEELKAQMASAGQ------GKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
Query: 958 NSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
+ E SE+ K VL LQEE+A + Q + ++ +E AD
Sbjct: 1731 SQNRE-----------SEKRLKGLEAEVLRLQEELAASDRARRQAQQDR---DEMADEVA 1776
Query: 1018 QETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE 1074
+ L+E+ L L Q +E L Q E+ +KL+ + + L +L+ E
Sbjct: 1777 NGNLSKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLNDRYRKLLLQVESLTTELSAE 1834
Query: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEME 1134
R + +LE + +L+ + + HK T + S++A+ E
Sbjct: 1835 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA---------LESKLAQAE 1885
Query: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP 1194
+ + E+ + +++ L L + +KR+ E+ V+Q E +R+ LR
Sbjct: 1886 E---QLEQETRERI-LSGKLVRRAEKRLKEV-----VLQVEEERRVADQLRD-------- 1928
Query: 1195 QIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
Q+ L + LKRQ E+E + + + R L +L
Sbjct: 1929 QLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR---------------------LQRELED 1967
Query: 1255 VSEELDVRKEEVLILRSQL 1273
V+E + EV LR++L
Sbjct: 1968 VTESAESMNREVTTLRNRL 1986
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 531 bits (1369), Expect = e-150
Identities = 339/1063 (31%), Positives = 554/1063 (52%), Gaps = 115/1063 (10%)
Query: 7 YTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPD 66
+T+ RVW+ + + + S + +++ + G+ Y T + +P
Sbjct: 5 FTEGTRVWLRENGQHFPSTV----NSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
Query: 67 ILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIIN 125
G +D+ +L+ LH ++++NL R+ ++ IYTY G +L ++NPY+ + +Y +
Sbjct: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQ-IYTYIGSILASVNPYQPIAGLYEPATME 119
Query: 126 AYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG 185
YS +++G++ PHIFA+A E Y+ + + NQ I++SGESGAGKT S K +++ + +S
Sbjct: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
Query: 186 SASEANVEEK-------VLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGAN 238
+ E +++EK +L S+PIME+ GNAKT N+NSSRFGK++++ ++ I G
Sbjct: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
Query: 239 MRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEG 298
+ YLLEK+RVV Q ERNYHIFY L A + E + L +N++Y Q G +
Sbjct: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
Query: 299 VDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLC 358
+ D + A ++ S+ + R+LAGILHLGN+ F + + L
Sbjct: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTA---LG 356
Query: 359 IFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDN 418
+L+G+D ++ L R + E + P++ QA ++RD+LA +YA F W++
Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
Query: 419 VNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 478
+N + + IG+LDI+GFE FE+N FEQF INYANEKLQ+ FN H+F LEQ EY
Sbjct: 417 INSRIKGN-EDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYS 475
Query: 479 KEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALF 538
+E + W ID+ DN C++LIE KLG+L L++EE P+ TD T +KL++ H N +
Sbjct: 476 REGLVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANN-HFY 534
Query: 539 EKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKA 598
KPR++ F ++H+A +V+Y G LEKN+DT ++ + +L+ S+F + +LF+
Sbjct: 535 VKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSR 594
Query: 599 ISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYV 658
+ + +K + TV QF++SLH LM TL+++ P +V
Sbjct: 595 NNQDTLKCG--------------------SKHRRPTVSSQFKDSLHSLMATLSSSNPFFV 634
Query: 659 RCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKD 718
RCIKPN K P FD+ + QLR G+LET+RI AG+ R +Q+F+ RY+VLM+
Sbjct: 635 RCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA 694
Query: 719 VLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIR 778
+ D + C ++L+ ++Q GKTK+F R LEK R +++ A + I+ +
Sbjct: 695 LPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVL 754
Query: 779 GWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRR 838
G+L RK+Y ++ + IIQK +R +++RRR+ +
Sbjct: 755 GFLARKQYRKVLYCVV-------------------------IIQKNYRAFLLRRRFLHLK 789
Query: 839 AATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRR 898
A IV Q LRG +AR YR++L E KR ++
Sbjct: 790 KAAIVFQKQLRGQIARRVYRQLLAE-------------------KREQEE--------KK 822
Query: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
+ E KK + E R ER E + +L+ + +E+ + K LE +
Sbjct: 823 KQEEEEKKKREEEERERER--------ERREAELRAQQEEETR-------KQQELEALQK 867
Query: 959 SETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQ 1018
S+ E ++L R +L +++ +L L++EI L++ EQ E E + ++
Sbjct: 868 SQKE---AELTR-ELEKQKENKQVEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQE 921
Query: 1019 ETEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKL 1060
+Q + L+EE QE E+LN + E +E+ L
Sbjct: 922 RRDQELRRLEEEACRAAQEFLESLN---FDEIDECVRNIERSL 961
Score = 63.5 bits (153), Expect = 2e-09
Identities = 72/307 (23%), Positives = 134/307 (43%), Gaps = 33/307 (10%)
Query: 787 LRMRKAAITMQRYVRGYQARCYAKFLR--------RTKAATIIQKY------WRMYVVRR 832
+R+RKA ++R + + R Y +R R K +++Q Y W++ +
Sbjct: 666 VRIRKAGYAVRRPFQDFYKR-YKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTK- 723
Query: 833 RYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYL 892
+ L+ L L + R ++ H A++I+ V G+LAR Y++ ++ ++ +
Sbjct: 724 ---------VFLRESLEQKLEKRREEEV--SHAAMVIRAHVLGFLARKQYRKVLYCVVII 772
Query: 893 QCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTN 952
Q +R + +R LK A ++ + I L K +++ K + EK
Sbjct: 773 QKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKR 832
Query: 953 LEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
E E E+ ++L R Q EE K L ++ A+L ++LE+ + K+ E
Sbjct: 833 EEEERERERERREAEL-RAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQV--EE 889
Query: 1013 ADRYKQETEQLVSNLKE--ENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070
R ++E E L +KE E +L + + L R Q+ + + E + E + L D
Sbjct: 890 ILRLEKEIEDL-QRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFD 948
Query: 1071 LNDERLR 1077
DE +R
Sbjct: 949 EIDECVR 955
Score = 37.7 bits (86), Expect = 0.10
Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 1166 EQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNE--LN 1223
++EK+ ++E +K E+ R + +E ++R A+ E E+ K+QELE+ K K
Sbjct: 818 QEEKKKQEEEEKKKREEEERERERERREAELR-AQQEEETRKQQELEALQKSQKEAELTR 876
Query: 1224 ELRKALSEKSAPEV 1237
EL K K E+
Sbjct: 877 ELEKQKENKQVEEI 890
Score = 35.0 bits (79), Expect = 0.68
Identities = 21/84 (25%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 1350 ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITR-L 1408
E + + ++ E E E E+++ +EE R+Q Q L+ +++ EA L E+ +
Sbjct: 827 EEKKKREEEERERERERREAELRAQQEEETRKQ----QELEALQKSQKEAELTRELEKQK 882
Query: 1409 TNENLDLMEQLEKQDKTVRKLKKQ 1432
N+ ++ + +LEK+ + ++++K+Q
Sbjct: 883 ENKQVEEILRLEKEIEDLQRMKEQ 906
Score = 33.5 bits (75), Expect = 2.0
Identities = 41/194 (21%), Positives = 79/194 (40%), Gaps = 30/194 (15%)
Query: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKK 1217
L++R L++ V Q +L + + + + E+R Q + E E K++E E ++
Sbjct: 781 LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
Query: 1218 LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
+ ELR E++ + +E L +E ++ +E L QK
Sbjct: 841 RERREAELRAQQEEETRKQQE----------LEALQKSQKEAELTRE--------LEKQK 882
Query: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
E Q ++ + +ED+Q+MK++ E++ L++ + L E
Sbjct: 883 ENKQVEEILRLEKE----IEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEE------ 932
Query: 1338 VYEGLKQANRLLES 1351
E + A LES
Sbjct: 933 --EACRAAQEFLES 944
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 520 bits (1338), Expect = e-147
Identities = 315/871 (36%), Positives = 473/871 (54%), Gaps = 96/871 (11%)
Query: 66 DILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIIN 125
D ++G D+ L L+E ++NL+ RF D IYTY G V++++NPY LPIY + +
Sbjct: 12 DNMIGVGDMVLLEPLNEETFINNLKKRF-DHSEIYTYIGSVVISVNPYRSLPIYSPEKVE 70
Query: 126 AYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG 185
Y +N ++ PHIFA+++EAY+ + +++Q I+++GESGAGKT ++K M Y A V G
Sbjct: 71 EYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCG 130
Query: 186 SASEAN-VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLL 244
+E N V+E++L SNP++E+ GNAKT RNDNSSRFGKY++I FD + +G + YLL
Sbjct: 131 KGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLL 190
Query: 245 EKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDAK 303
EKSRVV Q ERN+H+FYQL + A L+L + +NY S + GVDDA
Sbjct: 191 EKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-DSAKVNGVDDAA 249
Query: 304 EMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRD----ADSCTIPPKHEPLCI 359
R A ++G + + ++A +L LGN+ F D I K+E L
Sbjct: 250 NFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNE-LKE 308
Query: 360 FCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNV 419
C+L G+D + R + E ++ QA ARDALAK++Y++LF+W+V+ +
Sbjct: 309 ICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRI 368
Query: 420 NQALHSAVK-QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 478
N+++ + K + +GVLDIYGFE FE NSFEQF INY NEKLQQ F K EQEEY+
Sbjct: 369 NESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428
Query: 479 KEQIPWTLIDFYDNQPCINLIESKL-GILDLLDEECKMP-KGTDDTWAQKL--------- 527
+E I WT ID+++N +LIE+ GIL +LDEEC P TD+T+ +KL
Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488
Query: 528 YNTHLNKCALF-EKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFK 586
+ + ++KC+ F L + F IQH+A KV YQ EGF++KN D ++ + + + +
Sbjct: 489 FESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHA 548
Query: 587 MLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLL 646
++ LF + G P ++ + T G QF+ S+ L
Sbjct: 549 LIKSLFPE---------------------------GNPAKINLKRPPTAGSQFKASVATL 581
Query: 647 METLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEF 706
M+ L P+Y+RCIKPND K F+E Q+R G+LE +R+ AG+ R Y+
Sbjct: 582 MKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPC 641
Query: 707 FSRYRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRA 763
RY++L KQ + + + +L + ++Y FG++KIF R + + LE LR
Sbjct: 642 LERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRK 701
Query: 764 DKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQK 823
+L IQK RGW R +L M+K+ I +I
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQI-------------------------VIAA 736
Query: 824 YWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYK 883
++R Y ++RY+ +++ +V+QSY+RG+ A RKILRE K H K
Sbjct: 737 WYRRYAQQKRYQQTKSSALVIQSYIRGWKA----RKILRELK---------------HQK 777
Query: 884 RSMHAIIYLQCCFRRMMAKRELKKLKIEARS 914
R A+ + + A+REL++LK EAR+
Sbjct: 778 RCKEAVTTIAAYWHGTQARRELRRLKEEARN 808
Score = 38.5 bits (88), Expect = 0.062
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 13/150 (8%)
Query: 858 RKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER 917
RK E A +IQK RGW RTH+ + I + +RR ++ ++ K A ++
Sbjct: 700 RKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQS 759
Query: 918 YKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE 977
Y + G + RK+ + K K E +T + ++ + R +L RL+ EE
Sbjct: 760 YIR---GWK------ARKILRELKHQKRCKEAVTTIAAYWHG--TQARRELRRLK--EEA 806
Query: 978 AKVATGRVLSLQEEIAKLRKDLEQTRSEKK 1007
V+ +K R++L++ + E +
Sbjct: 807 RNKHAIAVIWAYWLGSKARRELKRLKEEAR 836
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,370,172
Number of Sequences: 37866
Number of extensions: 2952825
Number of successful extensions: 27915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 397
Number of HSP's successfully gapped in prelim test: 1218
Number of HSP's that attempted gapping in prelim test: 13165
Number of HSP's gapped (non-prelim): 7214
length of query: 1855
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1738
effective length of database: 13,817,196
effective search space: 24014286648
effective search space used: 24014286648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.