Search of human proteins with 213972619

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
         (1175 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]               2336   0.0  
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]                2330   0.0  
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]               2040   0.0  
gi|148839292 ATPase type 13A3 [Homo sapiens]                          844   0.0  
gi|66932949 ATPase type 13A4 [Homo sapiens]                           765   0.0  
gi|66730421 ATPase type 13A5 [Homo sapiens]                           763   0.0  
gi|170016077 ATPase type 13A1 [Homo sapiens]                          261   4e-69
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...   123   1e-27
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...   123   1e-27
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]   123   1e-27
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...   112   3e-24
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]   105   2e-22
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap...    97   1e-19
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...    97   1e-19
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...    95   4e-19
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...    93   1e-18
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...    93   1e-18
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...    92   3e-18
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...    92   3e-18
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...    92   3e-18
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...    92   3e-18
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...    91   5e-18
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa...    91   5e-18
gi|222352161 ATPase, class V, type 10D [Homo sapiens]                  87   9e-17
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...    85   4e-16
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...    85   4e-16
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...    80   1e-14
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...    80   1e-14
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...    80   1e-14
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...    80   1e-14

>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
          Length = 1175

 Score = 2336 bits (6054), Expect = 0.0
 Identities = 1175/1175 (100%), Positives = 1175/1175 (100%)

Query: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60
            MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
Sbjct: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60

Query: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120
            PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
Sbjct: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120

Query: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180
            PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
Sbjct: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180

Query: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240
            SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
Sbjct: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240

Query: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300
            FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
Sbjct: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300

Query: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360
            WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
Sbjct: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360

Query: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420
            AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
Sbjct: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420

Query: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480
            MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
Sbjct: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480

Query: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540
            SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
Sbjct: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540

Query: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600
            LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
Sbjct: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600

Query: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660
            PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
Sbjct: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660

Query: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720
            PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
Sbjct: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720

Query: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780
            NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
Sbjct: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780

Query: 781  PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840
            PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
Sbjct: 781  PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840

Query: 841  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900
            VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
Sbjct: 841  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900

Query: 901  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960
            FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
Sbjct: 901  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960

Query: 961  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020
            IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
Sbjct: 961  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020

Query: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1080
            QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
Sbjct: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1080

Query: 1081 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1140
            ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
Sbjct: 1081 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1140

Query: 1141 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1175
            LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
Sbjct: 1141 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1175


>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
          Length = 1180

 Score = 2330 bits (6038), Expect = 0.0
 Identities = 1175/1180 (99%), Positives = 1175/1180 (99%), Gaps = 5/1180 (0%)

Query: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60
            MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
Sbjct: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60

Query: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120
            PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
Sbjct: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120

Query: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ 175
            PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA     KRVLRYYLFQGQRYIWIETQQ
Sbjct: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 180

Query: 176  AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 235
            AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
Sbjct: 181  AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 240

Query: 236  YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 295
            YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
Sbjct: 241  YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 300

Query: 296  GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 355
            GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
Sbjct: 301  GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 360

Query: 356  LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 415
            LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
Sbjct: 361  LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 420

Query: 416  FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 475
            FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
Sbjct: 421  FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 480

Query: 476  TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 535
            TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
Sbjct: 481  TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 540

Query: 536  PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 595
            PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
Sbjct: 541  PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 600

Query: 596  AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 655
            AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
Sbjct: 601  AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 660

Query: 656  AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 715
            AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
Sbjct: 661  AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 720

Query: 716  LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 775
            LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
Sbjct: 721  LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 780

Query: 776  PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 835
            PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
Sbjct: 781  PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 840

Query: 836  LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 895
            LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
Sbjct: 841  LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 900

Query: 896  SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 955
            SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
Sbjct: 901  SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 960

Query: 956  LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 1015
            LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
Sbjct: 961  LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 1020

Query: 1016 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1075
            FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
Sbjct: 1021 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1080

Query: 1076 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ 1135
            FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
Sbjct: 1081 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ 1140

Query: 1136 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1175
            CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
Sbjct: 1141 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1180


>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
          Length = 1158

 Score = 2040 bits (5284), Expect = 0.0
 Identities = 1034/1073 (96%), Positives = 1034/1073 (96%), Gaps = 39/1073 (3%)

Query: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60
            MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
Sbjct: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60

Query: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120
            PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
Sbjct: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120

Query: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180
            PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
Sbjct: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180

Query: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240
            SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
Sbjct: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240

Query: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300
            FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
Sbjct: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300

Query: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360
            WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
Sbjct: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360

Query: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420
            AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
Sbjct: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420

Query: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480
            MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
Sbjct: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480

Query: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540
            SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
Sbjct: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540

Query: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600
            LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
Sbjct: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600

Query: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660
            PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
Sbjct: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660

Query: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720
            PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
Sbjct: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720

Query: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780
            NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
Sbjct: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780

Query: 781  PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840
            PASLEFLPMESPTAVNGV                                       KVL
Sbjct: 781  PASLEFLPMESPTAVNGV---------------------------------------KVL 801

Query: 841  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900
            VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
Sbjct: 802  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 861

Query: 901  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960
            FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
Sbjct: 862  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 921

Query: 961  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020
            IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
Sbjct: 922  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 981

Query: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1073
            QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN
Sbjct: 982  QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034


>gi|148839292 ATPase type 13A3 [Homo sapiens]
          Length = 1226

 Score =  844 bits (2181), Expect = 0.0
 Identities = 494/1196 (41%), Positives = 704/1196 (58%), Gaps = 68/1196 (5%)

Query: 35   VRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD 94
            + + GY  S W++    + V    G  LLL  W P W V+       +   E +++   D
Sbjct: 17   MEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTD 76

Query: 95   KEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHK-SEE 153
             E   W  F  +++  ++ E     SP+S +    +  AV  +     ++  ++ K S+ 
Sbjct: 77   -EFKMW--FCAKIRVLSL-ETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQT 132

Query: 154  AKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYG 212
              + +RY+     +Y W +T   F  +  LD G SC  ++     GL+      RK +YG
Sbjct: 133  ESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYG 192

Query: 213  PNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYK 272
             N I++ V S  +LL+ E LNP+Y FQ FS+ LW  D YY+YAL I ++S +SI  SLY 
Sbjct: 193  VNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYS 252

Query: 273  TRKQSQTLRDMVKL--SMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330
             RKQ   L DMV    ++RV VCR   E E + S++LVPGD +V+P  G +MPCDA L+ 
Sbjct: 253  IRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN 312

Query: 331  GECMVNESSLTGESIPVLKTALP------EGLGP--YCAETHRRHTLFCGTLILQARAYV 382
            G C+VNES LTGES+PV KT LP      +G+G   Y  ETH+RHTLFCGT ++Q R Y 
Sbjct: 313  GTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYT 372

Query: 383  GPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFIL 442
            G  V A+V RTGF T+KG LV SIL+P+P +FK Y+ +  F+  L  +A +G IY+I   
Sbjct: 373  GELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINS 432

Query: 443  YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKL 502
              N V +  I+I +LD++T+ VPPALPAAMT   +YAQ RL++ GIFCI P RIN+ G+L
Sbjct: 433  ILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQL 492

Query: 503  QLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPR----RLPVGPLLRALATCHALSR 558
             LVCFDKTGTLTEDGLD+ G+  ++   FL   PE       L     +  +ATCH+L++
Sbjct: 493  NLVCFDKTGTLTEDGLDLWGIQRVENARFLS--PEENVCNEMLVKSQFVACMATCHSLTK 550

Query: 559  LQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL-AVMRPP---------LWEPQLQ 608
            ++    GDP+DLKM E+ GW+LEE    ++A   +++  V+RPP             +++
Sbjct: 551  IEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEME 610

Query: 609  AMEEPPV-PVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPETVPTD 667
              E P    + ++ +FPFSSALQRMSVV    G  + +AY+KG+PE +AGLC PETVP D
Sbjct: 611  LFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVD 670

Query: 668  FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQT 727
            F  +L+ +T  G+RV+ALA + L +  +    Q ++RD +E ++  +GL++M+N LK +T
Sbjct: 671  FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQET 730

Query: 728  TPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFL 787
              V++ L +  IR VMVTGD++ TAV+VAR CGM+ PQ+ +II  A  P+ G+ A + + 
Sbjct: 731  PAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWH 790

Query: 788  PMES------PTAVNGVKDPDQAASYTVEPDPRSR-HLALSGPTFGIIVKHFPKLLPKVL 840
              +S      P+A++    P +    ++E    +R H A++G +F +I++HF  L+PK++
Sbjct: 791  YADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLM 850

Query: 841  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900
            + GTVFARMAP+QKT+L+  LQ + Y VGMCGDGANDCGALK A  GISLS+ EASV SP
Sbjct: 851  LHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASP 910

Query: 901  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960
            FTS   SI CVP +IREGR +L TSF VFK+MALYS+ Q+ SV +LY+I +NLGD QFL 
Sbjct: 911  FTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLF 970

Query: 961  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020
            IDL I   V   MS       L   RPP  L+S  +L S+L Q+++  G Q  G+F    
Sbjct: 971  IDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQ 1030

Query: 1021 QPWFVPL---------------------NRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1059
            QPW+                        N T     N+ NYENT VF +SSFQYLI+A A
Sbjct: 1031 QPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLIVAIA 1090

Query: 1060 VSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLV 1119
             SKG PFR+P Y N  F+ ++  L   ++ ++L P      +         +++ +L +V
Sbjct: 1091 FSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWRVTMLIIV 1150

Query: 1120 TLNFVGAFMLESVLDQ----CLPACLRRLRPKRASKKRFKQLERELAEQP-WPPLP 1170
             +N   +  +E  +D+    CLP  L     K+  K ++  L +EL   P WPP P
Sbjct: 1151 LVNAFVSITVEESVDRWGKCCLPWALG--CRKKTPKAKYMYLAQELLVDPEWPPKP 1204


>gi|66932949 ATPase type 13A4 [Homo sapiens]
          Length = 1196

 Score =  765 bits (1976), Expect = 0.0
 Identities = 468/1162 (40%), Positives = 675/1162 (58%), Gaps = 89/1162 (7%)

Query: 59   GIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDK-EDSSWQLFTVQVQTEAIGEGSL 117
            GI  L+F W+P W V     PC+L  A+T+++   D+ +  SW+   + +   A+     
Sbjct: 44   GILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKK-VIWIYLSALN---- 98

Query: 118  EPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRV---LRYYLFQGQRYIWIETQ 174
                          +A G  P+       +   +   ++    +R    Q  RY+W   +
Sbjct: 99   --------------SAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLE 144

Query: 175  QAFYQVSLLDHGRSCDDVHRS-RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
              F ++  L+   S   +H+    GL+ ++Q +R+ I GPN I + V    +LL+ E LN
Sbjct: 145  GQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLN 204

Query: 234  PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKL--SMRVC 291
            P+Y FQ FS+ LW ++ Y  YA  I ++S ISI L++Y  R+QS  L  +V+   S+ V 
Sbjct: 205  PFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVS 264

Query: 292  VC-RPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKT 350
            VC R  G +E ++S  LVPGD L+L     LMPCDA L+ G C+V+E  LTGESIPV KT
Sbjct: 265  VCGRKAGVQE-LESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKT 323

Query: 351  ALP--EGLGPYCAET---HRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSS 405
             LP  +   P+  ++   ++RH LFCGT ++QA+A     V AVV +TGF TAKG LV S
Sbjct: 324  PLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRS 383

Query: 406  ILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVP 465
            IL+P+P+NF+ Y+ +++F+  L   A +G IY++ +   +  P  E+V +ALD++T+ VP
Sbjct: 384  ILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVP 443

Query: 466  PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVP 525
            PALPAA+T   +YAQ RL+++GIFCI P RIN+ G+L LVCFDKTGTLT DGLD+ GVV 
Sbjct: 444  PALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVS 503

Query: 526  LKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEE 583
                 F  +      + LP GPL  A+A+CH+L  L  T  GDP+DLKM E+T W     
Sbjct: 504  CDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW----- 558

Query: 584  PAADSAFGTQVLAVMRPP----LWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWP 639
               + AF      +   P    + +P   A + P   +++LH+FPFSSALQRM+V+V   
Sbjct: 559  ---EMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEM 615

Query: 640  GATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAA 699
            G  +  A++KG+PE VA  C PETVPT F   LQ YT  G+RV+ALA K L        A
Sbjct: 616  GGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---HHA 671

Query: 700  QQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGC 759
              LTR+TVE DL  LGLL++ N LK +T PV++ L   RIR VM+TGDNLQTA+TVAR  
Sbjct: 672  TTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKS 731

Query: 760  GMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAV------NGVKDPDQAASYTVEPDP 813
            GMV+  + +I++ A        AS+ +  +E    +      N +   D+ +    E   
Sbjct: 732  GMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREG-- 789

Query: 814  RSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGD 873
             S H AL+G +F +I +HF  LLPK+L+ GT+FARM+P QK+ LV E QKL Y VGMCGD
Sbjct: 790  -SYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGD 848

Query: 874  GANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMA 933
            GANDCGALK A VGISLS+ EASV SPFTS   +IECVP +I+EGR +L TSF +FKYMA
Sbjct: 849  GANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMA 908

Query: 934  LYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLS 993
            LYS+ Q++ VL+LY    +L + QFL  DL ITT + V M+  G    L   RP G L+S
Sbjct: 909  LYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLIS 968

Query: 994  VPVLSSLLLQMVLVTGVQLGGYFLTLAQPWF---------------VPLNRTVAAPDNL- 1037
             P+L S++  ++L   + + G+ L   QPW+                 L  +  AP+ + 
Sbjct: 969  PPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKME 1028

Query: 1038 -----PNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVL 1092
                  ++ENT V+ L +   + +A   SKG PFR+P YTN  F++ L +   V + ++ 
Sbjct: 1029 SNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILF 1088

Query: 1093 --VPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVL--DQCLPACLRRLRPKR 1148
              +P L +    L   T   ++  ++ +++LNF+ + + E  +  ++ L   ++R    +
Sbjct: 1089 ADIPELYRRLDLL--CTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIKRCFGYQ 1146

Query: 1149 ASKKRFKQLERELAEQP-WPPL 1169
             SK +++  +R+LA  P WPPL
Sbjct: 1147 -SKSQYRIWQRDLANDPSWPPL 1167


>gi|66730421 ATPase type 13A5 [Homo sapiens]
          Length = 1218

 Score =  763 bits (1970), Expect = 0.0
 Identities = 470/1169 (40%), Positives = 659/1169 (56%), Gaps = 104/1169 (8%)

Query: 62   LLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD-------KEDSSWQLFTVQVQTEAIGE 114
            LL+F W+P W V     PC L  A+T+++   D       K+     L T++       E
Sbjct: 48   LLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWE 107

Query: 115  GSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQ 174
             SL     S      +QA +                  + +  LR    Q  RY+W + +
Sbjct: 108  ESLVADRHSVI----NQALI------------------KPELKLRCMEVQKIRYVWNDLE 145

Query: 175  QAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
            + F +V LL+   SC D+H++   GL+ ++Q VR+ + GPN I + ++   +LLV + LN
Sbjct: 146  KRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLN 205

Query: 234  PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMV----KLSMR 289
            P+Y FQAF++ LWL+  Y  Y++ I +++ ISI LS+Y  R+QS  L ++V    K+ + 
Sbjct: 206  PFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVT 265

Query: 290  VCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLK 349
            + V   G EE  ++S  LVPGD L+LP +  L PCDA L+ G C+VNE  LTGESIPV K
Sbjct: 266  IIVKDKGLEE--LESRLLVPGDILILPGKFSL-PCDAVLIDGSCVVNEGMLTGESIPVTK 322

Query: 350  TALP--EGLGPY---CAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVS 404
            T LP  E   P+     E +R+H LFCGT ++Q +      V AVV +TG+ TAKG LV 
Sbjct: 323  TPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVR 382

Query: 405  SILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVV 464
            SIL+PRP+NFK Y  + KF+  L+ L ++G  Y++ +   + VP  + V  AL L+TV V
Sbjct: 383  SILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTV 442

Query: 465  PPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVV 524
            PP LPAA+T+  +YAQ RL+++ IFCI P RIN+ G++ LVCFDKTGTLTEDGLD+ G V
Sbjct: 443  PPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV 502

Query: 525  PLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEE 582
            P     F         + +P  PL  A+A+CH+L  L  T  GDP+DLKM E T W +E+
Sbjct: 503  PTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMED 562

Query: 583  EPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGAT 642
                   FGT V  +++P       +A + P   +  L +FPFSS+LQRMSV+    G  
Sbjct: 563  CIVDSCKFGTSVSNIIKPGP-----KASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGEN 617

Query: 643  QPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQL 702
                Y+KG+PE+VA  C  ETVP +F Q L+SYT  G+RV+ALA K L  + +L   + L
Sbjct: 618  HFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLK-MGNLSEVEHL 676

Query: 703  TRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMV 762
             R+ VE +L+ LGLL+M N LK +T  V++ L   RIR VM+TGDNLQTA+TVA+   M+
Sbjct: 677  AREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMI 736

Query: 763  APQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSR---HLA 819
             P   +IIV A  PE   PAS+ +  +E+     G K+       +  P        H A
Sbjct: 737  PPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFA 796

Query: 820  LSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 879
            +SG ++ +I +HF  LLPK+LV GTVFARM+P QK+ L+ E QKL Y VGMCGDGANDCG
Sbjct: 797  MSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCG 856

Query: 880  ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 939
            ALKAA  GISLS+ EASV SPFTS   +I+CVP +IREGR +L +SF VFKY+ +Y + Q
Sbjct: 857  ALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQ 916

Query: 940  FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 999
            FIS L+LY      G+ Q+L  D+ IT  V + MS T     L   RP G LLS P+L S
Sbjct: 917  FISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLS 976

Query: 1000 LLLQMVLVTGVQLGGYFLTLAQPWF--------------------VPLNR-----TVAAP 1034
            + L       VQ+  +     QPW+                    V L R         P
Sbjct: 977  IFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIP 1036

Query: 1035 DNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPF----LVALALLSSVLV-- 1088
             ++ ++E T ++ +++  Y+ +A   SKG PFR+P+YTN  F    L AL L   +L   
Sbjct: 1037 GSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSD 1096

Query: 1089 ------GLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLE-SVLDQCLPACL 1141
                  G+ L+P            T T +++L+L +    F  AF +E S+L       L
Sbjct: 1097 FQVIYRGMELIP------------TITSWRVLILVVALTQFCVAFFVEDSILQNHELWLL 1144

Query: 1142 RRLRPKRASKKRFKQLERELAE-QPWPPL 1169
             +      SK +++  +++LAE   WPP+
Sbjct: 1145 IKREFGFYSKSQYRTWQKKLAEDSTWPPI 1173


>gi|170016077 ATPase type 13A1 [Homo sapiens]
          Length = 1204

 Score =  261 bits (666), Expect = 4e-69
 Identities = 217/730 (29%), Positives = 355/730 (48%), Gaps = 83/730 (11%)

Query: 193 HRSRHGLSLQDQMVRKAI--YGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++S  G   +D  +R A   +G N   + V  + +L  + A  P++ FQ F + LW  D 
Sbjct: 203 YQSNRGFQ-EDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDE 261

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEW--VDSSELV 308
           Y++Y+  +F +S + +       ++Q + + ++ K+  +  + +     +W  + S E+V
Sbjct: 262 YWYYS--VFTLSML-VAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIV 318

Query: 309 PGDCLVL---PQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPY----CA 361
           PGD + +   PQE  L+PCD  L+ G C+V+E+ LTGES+P +K  + E L P       
Sbjct: 319 PGDIVSIGRSPQEN-LVPCDVLLLRGRCIVDEAMLTGESVPQMKEPI-EDLSPDRVLDLQ 376

Query: 362 ETHRRHTLFCGTLILQ----ARAYVG-----PHVLAVVTRTGFCTAKGGLVSSILHPRPI 412
              R H +F GT ++Q     +A  G        +A V RTGF T++G L+ +IL     
Sbjct: 377 ADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKR 436

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL-----YRNRVPLNEIVIRALDLVTVVVPPA 467
                  +  F+  L V A+    Y ++I       RNR  L    +    ++T VVPP 
Sbjct: 437 VTANNLETFIFILFLLVFAIAAAAY-VWIEGTKDPSRNRYKL---FLECTLILTSVVPPE 492

Query: 468 LPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLK 527
           LP  +++    +   L +  ++C  P RI   GK+++ CFDKTGTLT D L V GV  L+
Sbjct: 493 LPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLR 552

Query: 528 -GQAFLPLVPEPRRLPVGPLLRALATCHALSRLQD-TPVGDPMDLKMVESTGWVL-EEEP 584
            G+   P+   P         RALA+CH+L +L D T VGDP++  M+ +  W L ++E 
Sbjct: 553 DGKEVTPVSSIPVETH-----RALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEK 607

Query: 585 AADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQP 644
               +  TQ L + +                      RF F+SAL+RMSV+ ++      
Sbjct: 608 VFPRSIKTQGLKIHQ----------------------RFHFASALKRMSVLASYEKLGST 645

Query: 645 E----AYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 700
           +    A VKG+PE +  + +    P D+  +    +  G RV+AL  K L  +   + A+
Sbjct: 646 DLCYIAAVKGAPETLHSMFSQ--CPPDYHHIHTEISREGARVLALGYKELGHLTH-QQAR 702

Query: 701 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 760
           ++ R+ +E  L  +G +V+   LK  +  VI+ ++    R VM+TGDN  TA  VA+   
Sbjct: 703 EVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELH 762

Query: 761 MVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLAL 820
            +     LI+     P   +    E+  ++    +   +   +A +           L L
Sbjct: 763 FIEKAHTLIL----QPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYA-------LCL 811

Query: 821 SGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGA 880
           +G     +    P+ L +++    VFAR+AP+QK  ++  L++L Y   MCGDG ND GA
Sbjct: 812 TGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGA 871

Query: 881 LKAADVGISL 890
           LK ADVG++L
Sbjct: 872 LKHADVGVAL 881



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 70/261 (26%), Positives = 122/261 (46%), Gaps = 43/261 (16%)

Query: 894  EASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNL 953
            +AS+ +PFTS ++SI+C+  VI++GRC+L T+  +FK +AL +L    S  +LY      
Sbjct: 953  DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012

Query: 954  GDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLG 1013
             D Q     L++     + +SR+ P   L R RP   + ++  + +++LQ  +       
Sbjct: 1013 SDFQATLQGLLLAGCF-LFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFV------- 1064

Query: 1014 GYFLTLA-------------QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAV 1060
             +FL+L              Q  FV L +        P+  N+ V+ ++    +   A  
Sbjct: 1065 -HFLSLVYLYREAQARSPEKQEQFVDLYKEFE-----PSLVNSTVYIMAMAMQMATFAIN 1118

Query: 1061 SKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVP--------GLLQGPLALRNITDTGFK 1112
             KG PF   L  N P + +LA+    ++GL+L          GL+  P+         FK
Sbjct: 1119 YKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVE--------FK 1170

Query: 1113 LLLLGLVTLNFVGAFMLESVL 1133
            L++  ++ L+F  A + + VL
Sbjct: 1171 LVIAQVLLLDFCLALLADRVL 1191


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
          Length = 1023

 Score =  123 bits (308), Expect = 1e-27
 Identities = 212/911 (23%), Positives = 363/911 (39%), Gaps = 127/911 (13%)

Query: 179  QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
            +VS+ DH  S D++HR        GL+        A  GPN ++ P  +   +     L 
Sbjct: 38   EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 96

Query: 234  PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274
                F  FS+ LW+     + A  I                 ++S++ I   C S Y+  
Sbjct: 97   ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 152

Query: 275  KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333
            K S+ +     +  +  +    GE+  +++ E+V GD LV  + G  +P D  ++ A  C
Sbjct: 153  KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 211

Query: 334  MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393
             V+ SSLTGES P  +T  P+       ET  R+  F  T  ++  A        +V  T
Sbjct: 212  KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 261

Query: 394  GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449
            G  T  G +  ++S L     PI  +  +H +  +  ++V   LG  + I  L      L
Sbjct: 262  GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 318

Query: 450  NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509
             E VI  + ++   VP  L A +TVC      R+ R+     +   +   G    +C DK
Sbjct: 319  -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 377

Query: 510  TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569
            TGTLT++    M V  +     +               +  AT  ALSR+    + +   
Sbjct: 378  TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 432

Query: 570  LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629
             +  +    +L+   A D++    +  +      E    +++E     + +   PF+S  
Sbjct: 433  FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 486

Query: 630  QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676
            +    +   P  ++P+    +KG+PE +   C+            E +   F        
Sbjct: 487  KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 546

Query: 677  AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
              G RV+      LP     E  Q  T D      +L  +GL+ M +  +      +   
Sbjct: 547  GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 606

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794
            R   I+ +MVTGD+  TA  +A+G G+++                   ++E +       
Sbjct: 607  RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE---------------TVEDIAARLNIP 651

Query: 795  VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854
            V+ V   D  A      D +     ++      I+K+  ++         VFAR +P+QK
Sbjct: 652  VSQVNPRDAKACVVHGSDLKD----MTSEQLDDILKYHTEI---------VFARTSPQQK 698

Query: 855  TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----C 910
              +V   Q+    V + GDG ND  ALK AD+G+++  A  S VS   + M  ++     
Sbjct: 699  LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDDNFAS 757

Query: 911  VPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLV 964
            +   + EGR   D      K    Y+LT  I       + I+  I   LG +  L IDL 
Sbjct: 758  IVTGVEEGRLIFDN----LKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLG 813

Query: 965  ITTTVAVLMSRTGPALVLGRVRP----PGALLSVPVLSSLLLQMVLVTGVQLGG---YFL 1017
                 A+ ++       + + +P       L++  ++S    Q+ ++    LGG   YF+
Sbjct: 814  TDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQA--LGGFFTYFV 871

Query: 1018 TLAQPWFVPLN 1028
             LA+  F+P++
Sbjct: 872  ILAENGFLPIH 882


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens]
          Length = 992

 Score =  123 bits (308), Expect = 1e-27
 Identities = 212/911 (23%), Positives = 363/911 (39%), Gaps = 127/911 (13%)

Query: 179  QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
            +VS+ DH  S D++HR        GL+        A  GPN ++ P  +   +     L 
Sbjct: 7    EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 65

Query: 234  PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274
                F  FS+ LW+     + A  I                 ++S++ I   C S Y+  
Sbjct: 66   ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 121

Query: 275  KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333
            K S+ +     +  +  +    GE+  +++ E+V GD LV  + G  +P D  ++ A  C
Sbjct: 122  KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 180

Query: 334  MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393
             V+ SSLTGES P  +T  P+       ET  R+  F  T  ++  A        +V  T
Sbjct: 181  KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 230

Query: 394  GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449
            G  T  G +  ++S L     PI  +  +H +  +  ++V   LG  + I  L      L
Sbjct: 231  GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 287

Query: 450  NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509
             E VI  + ++   VP  L A +TVC      R+ R+     +   +   G    +C DK
Sbjct: 288  -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 346

Query: 510  TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569
            TGTLT++    M V  +     +               +  AT  ALSR+    + +   
Sbjct: 347  TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 401

Query: 570  LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629
             +  +    +L+   A D++    +  +      E    +++E     + +   PF+S  
Sbjct: 402  FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 455

Query: 630  QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676
            +    +   P  ++P+    +KG+PE +   C+            E +   F        
Sbjct: 456  KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 515

Query: 677  AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
              G RV+      LP     E  Q  T D      +L  +GL+ M +  +      +   
Sbjct: 516  GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 575

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794
            R   I+ +MVTGD+  TA  +A+G G+++                   ++E +       
Sbjct: 576  RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE---------------TVEDIAARLNIP 620

Query: 795  VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854
            V+ V   D  A      D +     ++      I+K+  ++         VFAR +P+QK
Sbjct: 621  VSQVNPRDAKACVVHGSDLKD----MTSEQLDDILKYHTEI---------VFARTSPQQK 667

Query: 855  TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----C 910
              +V   Q+    V + GDG ND  ALK AD+G+++  A  S VS   + M  ++     
Sbjct: 668  LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDDNFAS 726

Query: 911  VPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLV 964
            +   + EGR   D      K    Y+LT  I       + I+  I   LG +  L IDL 
Sbjct: 727  IVTGVEEGRLIFDN----LKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLG 782

Query: 965  ITTTVAVLMSRTGPALVLGRVRP----PGALLSVPVLSSLLLQMVLVTGVQLGG---YFL 1017
                 A+ ++       + + +P       L++  ++S    Q+ ++    LGG   YF+
Sbjct: 783  TDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQA--LGGFFTYFV 840

Query: 1018 TLAQPWFVPLN 1028
             LA+  F+P++
Sbjct: 841  ILAENGFLPIH 851


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score =  123 bits (308), Expect = 1e-27
 Identities = 212/911 (23%), Positives = 363/911 (39%), Gaps = 127/911 (13%)

Query: 179  QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
            +VS+ DH  S D++HR        GL+        A  GPN ++ P  +   +     L 
Sbjct: 38   EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 96

Query: 234  PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274
                F  FS+ LW+     + A  I                 ++S++ I   C S Y+  
Sbjct: 97   ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 152

Query: 275  KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333
            K S+ +     +  +  +    GE+  +++ E+V GD LV  + G  +P D  ++ A  C
Sbjct: 153  KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 211

Query: 334  MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393
             V+ SSLTGES P  +T  P+       ET  R+  F  T  ++  A        +V  T
Sbjct: 212  KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 261

Query: 394  GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449
            G  T  G +  ++S L     PI  +  +H +  +  ++V   LG  + I  L      L
Sbjct: 262  GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 318

Query: 450  NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509
             E VI  + ++   VP  L A +TVC      R+ R+     +   +   G    +C DK
Sbjct: 319  -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 377

Query: 510  TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569
            TGTLT++    M V  +     +               +  AT  ALSR+    + +   
Sbjct: 378  TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 432

Query: 570  LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629
             +  +    +L+   A D++    +  +      E    +++E     + +   PF+S  
Sbjct: 433  FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 486

Query: 630  QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676
            +    +   P  ++P+    +KG+PE +   C+            E +   F        
Sbjct: 487  KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 546

Query: 677  AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
              G RV+      LP     E  Q  T D      +L  +GL+ M +  +      +   
Sbjct: 547  GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 606

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794
            R   I+ +MVTGD+  TA  +A+G G+++                   ++E +       
Sbjct: 607  RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE---------------TVEDIAARLNIP 651

Query: 795  VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854
            V+ V   D  A      D +     ++      I+K+  ++         VFAR +P+QK
Sbjct: 652  VSQVNPRDAKACVVHGSDLKD----MTSEQLDDILKYHTEI---------VFARTSPQQK 698

Query: 855  TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----C 910
              +V   Q+    V + GDG ND  ALK AD+G+++  A  S VS   + M  ++     
Sbjct: 699  LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDDNFAS 757

Query: 911  VPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLV 964
            +   + EGR   D      K    Y+LT  I       + I+  I   LG +  L IDL 
Sbjct: 758  IVTGVEEGRLIFDN----LKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLG 813

Query: 965  ITTTVAVLMSRTGPALVLGRVRP----PGALLSVPVLSSLLLQMVLVTGVQLGG---YFL 1017
                 A+ ++       + + +P       L++  ++S    Q+ ++    LGG   YF+
Sbjct: 814  TDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQA--LGGFFTYFV 871

Query: 1018 TLAQPWFVPLN 1028
             LA+  F+P++
Sbjct: 872  ILAENGFLPIH 882


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score =  112 bits (279), Expect = 3e-24
 Identities = 184/793 (23%), Positives = 311/793 (39%), Gaps = 99/793 (12%)

Query: 212 GPNVISIP------VKSYPQLLVDEALNPYYG----FQAFSIALWLADHYYWYALCIFLI 261
           GPN ++ P      VK   QL    +L  + G    F A+SI ++  +      L + ++
Sbjct: 84  GPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIV 143

Query: 262 SSISI----CLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQ 317
            S+ +    C S Y+  K S+ +     +  +  +   GGE+  ++  E+V GD LV  +
Sbjct: 144 LSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGD-LVEIK 202

Query: 318 EGGLMPCDAALVAGE-CMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLIL 376
            G  +P D  L++ + C V+ SSLTGES P  ++  P+       ET  R+  F  T  +
Sbjct: 203 GGDRVPADLRLISAQGCKVDNSSLTGESEPQSRS--PDFTHENPLET--RNICFFSTNCV 258

Query: 377 QARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLAL-LGT 435
           +  A        +V  TG  T  G + S                  F+  ++V+A+ LG 
Sbjct: 259 EGTAR------GIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGV 312

Query: 436 IYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLR 495
            +    L      L E +I  + ++   VP  L A +TVC      R+ R+     +   
Sbjct: 313 TFFALSLLLGYGWL-EAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEA 371

Query: 496 INLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHA 555
           +   G    +C DKTGTLT++    M V  +     +               ++  T   
Sbjct: 372 VETLGSTSTICSDKTGTLTQNR---MTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFM 428

Query: 556 LSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPV 615
           L+R+    + +  D K  +    + +     D++    +  +      E    ++ E   
Sbjct: 429 LARI--AGLCNRADFKANQEILPIAKRATTGDASESALLKFI------EQSYSSVAEMRE 480

Query: 616 PVSVLHRFPFSSALQ-RMSVVVAWPGATQPEAYVKGSPELVAGLCNP-----------ET 663
               +   PF+S  + +MS+ +    +      +KG+PE +   C+            + 
Sbjct: 481 KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE 540

Query: 664 VPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVE---GDLSLLGLLVMR 720
           +   F          G RV+      LP+  S         D +     +L  +GL+ M 
Sbjct: 541 MKEAFQNAYLELGGLGERVLGFCFLNLPS--SFSKGFPFNTDEINFPMDNLCFVGLISMI 598

Query: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780
           +  +      +   R   I+ +MVTGD+  TA  +A+G G        II   T      
Sbjct: 599 DPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IISEGTETAEEV 650

Query: 781 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840
            A L+ +P+    A         AA   V      +   +       I+++ P++     
Sbjct: 651 AARLK-IPISKVDA--------SAAKAIVVHGAELKD--IQSKQLDQILQNHPEI----- 694

Query: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900
               VFAR +P+QK  +V   Q+L   V + GDG ND  ALK AD+GI++     S VS 
Sbjct: 695 ----VFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMG-ISGSDVSK 749

Query: 901 FTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTIN 950
             + M  ++     +   + EGR   D      K   +Y+LT  I       + I+  I 
Sbjct: 750 QAADMILLDDNFASIVTGVEEGRLIFDN----LKKSIMYTLTSNIPEITPFLMFIILGIP 805

Query: 951 TNLGDLQFLAIDL 963
             LG +  L IDL
Sbjct: 806 LPLGTITILCIDL 818


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score =  105 bits (263), Expect = 2e-22
 Identities = 196/871 (22%), Positives = 350/871 (40%), Gaps = 122/871 (14%)

Query: 212  GPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLS-- 269
            GPN ++ P K  P+++  + L    G   FSI LW+     W A  I   S  S  L+  
Sbjct: 91   GPNSLT-PPKQTPEIV--KFLKQMVG--GFSILLWVGAFLCWIAYGIQYSSDKSASLNNV 145

Query: 270  -----------------LYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDC 312
                              Y+  K +  +    K+  +  +     E++ + S +LV GD 
Sbjct: 146  YLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGD- 204

Query: 313  LVLPQEGGLMPCDAALVAGE-CMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFC 371
            +V  + G  +P D  +++ + C V+ SSLTGES P           P  +E    + L  
Sbjct: 205  IVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQ----------PRSSEFTHENPLET 254

Query: 372  GTLILQARAYVGPHVLAVVTRTGFCTAKG---GLVSSILHPR-PINFKFYKHSMKFVAAL 427
              +   +   +   V  +V  TG  T  G    L S + + + PI  +  +H +  VA +
Sbjct: 255  KNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEI-EHFVHIVAGV 313

Query: 428  SV-LALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQ 486
            +V + +L  I ++ + Y+    + + +I  + ++   VP  L A +TV       R+ ++
Sbjct: 314  AVSIGILFFIIAVSLKYQ----VLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKK 369

Query: 487  GIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPL 546
                 +   +   G   ++C DKTGTLT++ + V  +     Q F+    E     V   
Sbjct: 370  NCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLW-FDNQIFVADTSEDHSNQV--F 426

Query: 547  LRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL---AVMRPPLW 603
             ++  T  +LS++    + +  + K  +    ++++    D A  T +L    V+   + 
Sbjct: 427  DQSSRTWASLSKI--ITLCNRAEFKPGQENVPIMKKAVIGD-ASETALLKFSEVILGDVM 483

Query: 604  EPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLC---- 659
            E + +  +   +P +  ++F  S  +  M      P   +    +KG+PE +   C    
Sbjct: 484  EIRKRNRKVAEIPFNSTNKFQLS--IHEMDD----PHGKRFLMVMKGAPERILEKCSTIM 537

Query: 660  -NPETVPTDFAQMLQSYTA------AGYRVVALASKPLPT--VPSLEAAQQLTRDTVEGD 710
             N E  P D +     +TA       G RV+      LP    P   +      +    +
Sbjct: 538  INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSN 597

Query: 711  LSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLII 770
            L  +GLL M +  +      +   R   I+ +MVTGD+  TA  +A+  G+++       
Sbjct: 598  LCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSE--- 654

Query: 771  VHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVK 830
                        ++E +      AV  V   D  A+     + +     +S      I+ 
Sbjct: 655  ------------TVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKD----MSSEQLDEILA 698

Query: 831  HFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISL 890
            ++         Q  VFAR +P+QK  +V   Q+    V + GDG ND  ALK AD+GI++
Sbjct: 699  NY---------QEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAM 749

Query: 891  SQAEASVVSPFTSSMA---SIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFIS----- 942
              A +         +    +   +   + EGR   D      K    YSLT+ I+     
Sbjct: 750  GIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDN----LKKTIAYSLTKNIAELCPF 805

Query: 943  -VLILYTINTNLGDLQFLAIDL--VITTTVAVLMSRTGPALVLGRVRPPG--ALLSVP-- 995
             + I+  +   +G +  L IDL   I  ++A+   +    ++  + R      L++ P  
Sbjct: 806  LIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLA 865

Query: 996  VLSSLLLQMVLVTGVQLGGYFLTLAQPWFVP 1026
            V S L + ++   G  L  YF   AQ  F+P
Sbjct: 866  VYSYLHIGLMQALGAFL-VYFTVYAQEGFLP 895


>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
          Length = 1243

 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 151/733 (20%), Positives = 281/733 (38%), Gaps = 91/733 (12%)

Query: 296  GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 355
            G EEE  D   +  GD L LP   G    +AA  A   +VN     G ++   ++   + 
Sbjct: 293  GEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDG-NVDASQSKAKQQ 351

Query: 356  LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVV----TRTGFCTAKGGLVSSILHPRP 411
             G    E     +   G    + +A +     +V+    T+      K GLV S +    
Sbjct: 352  DGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAI--TV 409

Query: 412  INFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAA 471
            I    Y     FV  ++    L     +++ Y       +  I  + ++ V VP  LP A
Sbjct: 410  IILVLYFTVDTFV--VNKKPWLPECTPVYVQY-----FVKFFIIGVTVLVVAVPEGLPLA 462

Query: 472  MTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAF 531
            +T+   Y+  ++ +      H       G    +C DKTGTLT + + V  V    G   
Sbjct: 463  VTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV--VQAYVGDVH 520

Query: 532  LPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFG 591
               +P+P  +     +  L    A++    T +  P      E  G  L  +    +  G
Sbjct: 521  YKEIPDPSSINT-KTMELLINAIAINSAYTTKILPP------EKEG-ALPRQVGNKTECG 572

Query: 592  TQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGS 651
                 +     +EP    M E      +   + F+S  + MS V+  P  +    Y KG+
Sbjct: 573  LLGFVLDLKQDYEPVRSQMPEE----KLYKVYTFNSVRKSMSTVIKLPDESF-RMYSKGA 627

Query: 652  PELVAGLC-------------NPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEA 698
             E+V   C              P        ++++     G R + +A +  P+ P  + 
Sbjct: 628  SEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW 687

Query: 699  AQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARG 758
              +   + +  +L+ + ++ + + ++P+    I+  +R  I   MVTGDN+ TA  +A  
Sbjct: 688  DNE---NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIK 744

Query: 759  CGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHL 818
            CG++ P E  + +      R        +  E    +                 P+ R L
Sbjct: 745  CGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI----------------WPKLRVL 788

Query: 819  ALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 878
            A S PT     KH        LV+G + +    +++             V + GDG ND 
Sbjct: 789  ARSSPT----DKH-------TLVKGIIDSTHTEQRQV------------VAVTGDGTNDG 825

Query: 879  GALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLT 938
             ALK ADVG ++  A   V    +  + + +    +++      +   S+ K++      
Sbjct: 826  PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 885

Query: 939  QFISVLILY-----TINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLS 993
              ++V++ +     T ++ L  +Q L ++L++ T  ++ ++   P   L   +P G   +
Sbjct: 886  NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGR--N 943

Query: 994  VPVLSSLLLQMVL 1006
             P++S  +++ +L
Sbjct: 944  KPLISRTMMKNIL 956



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 7/96 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   +  +E+V GD +  
Sbjct: 162 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVVR-AGQVVQIPVAEIVVGD-IAQ 215

Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350
            + G L+P D   + G +  ++ESSLTGES  V K+
Sbjct: 216 VKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS 251


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
            sapiens]
          Length = 946

 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 220/998 (22%), Positives = 380/998 (38%), Gaps = 167/998 (16%)

Query: 189  CDDVHRSRHGLSLQDQMVRKAIYGPNVI----SIPV-KSYPQLLVDEALNPYYGFQAFSI 243
            C D+H    GLS      R+  +G N      S PV K Y    +D+  NP       S 
Sbjct: 70   CVDLHT---GLSEFSVTQRRLAHGWNEFVADNSEPVWKKY----LDQFKNPLILLLLGSA 122

Query: 244  ALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVD 303
             + +    Y  A+ I     + + ++  +  +  ++L ++ K+    C C   G+ + + 
Sbjct: 123  LVSVLTKEYEDAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPECNCLREGKLQHLL 182

Query: 304  SSELVPGDCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALP-EGLGPYCA 361
            + ELVPGD + L   G  +P D  L    + +V+ESS TGE+ P  KT  P  G G    
Sbjct: 183  ARELVPGDVVSL-SIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDL-- 239

Query: 362  ETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSM 421
             T   + +F GTL+   R         VV  TG  +++ G V  ++          + SM
Sbjct: 240  -TTLSNIVFMGTLVQYGRGQ------GVVIGTGE-SSQFGEVFKMMQAEETPKTPLQKSM 291

Query: 422  KFVAALSVLALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480
              +     L   G I  I ++ +     L  +    + L    +P  LP  + V  +   
Sbjct: 292  DRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGV 351

Query: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKG-QAFLPLVPEPR 539
             R+ ++ +       +   G   ++C DKTGTLT + + V  +V   G +A +  V    
Sbjct: 352  LRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDG 411

Query: 540  RLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMR 599
            +  V      L +   +    +  VG  ++   V +   + +         G  +   M+
Sbjct: 412  QGTVC----LLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMK 467

Query: 600  PPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAY-VKGSPELVAGL 658
              L + +   + +  +P        FSS  + M+V  +     Q + Y +KG+ E V   
Sbjct: 468  MDLSDIKNSYIRKKEIP--------FSSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRY 519

Query: 659  C---NPETVPTDFAQMLQSYT--------AAGYRVVALASKPLPTVPSLEAAQQLTRDTV 707
            C   N   +P       +S+         + G RV+ALAS P                  
Sbjct: 520  CTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGP-----------------E 562

Query: 708  EGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEH 767
             G L+ LGL+ + +  +      +Q L  + +   M+TGD L+TA+ + R  G+      
Sbjct: 563  LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLC----- 617

Query: 768  LIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGI 827
                            L+ +  E   +V   +  D+    +V               F  
Sbjct: 618  -------------NGKLQAMSGEEVDSVEKGELADRVGKVSV--------------FFRT 650

Query: 828  IVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVG 887
              KH  K++  +   G +                      V M GDG ND  ALK+AD+G
Sbjct: 651  SPKHKLKIIKALQESGAI----------------------VAMTGDGVNDAVALKSADIG 688

Query: 888  ISLSQAEASVVSPFTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLTQFISV 943
            I++ Q   + VS   ++M  ++     +   + EG+      F   K    + L+  IS 
Sbjct: 689  IAMGQT-GTDVSKEAANMILVDDDFSAIMNAVEEGK----GIFYNIKNFVRFQLSTSISA 743

Query: 944  LILYTINT------NLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVL 997
            L L T++T       L  +Q L I++++    A  +    P       +PP ++    + 
Sbjct: 744  LSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLG-VEPVDKDAFRQPPRSVRDTILS 802

Query: 998  SSLLLQMVLVTGVQLGGYFLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILA 1057
             +L+L++++   + + G   TL   W          P++  +   T   + + F +  L 
Sbjct: 803  RALILKILMSAAIIISG---TLFIFW-------KEMPEDRASTPRTTTMTFTCFVFFDLF 852

Query: 1058 AAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPGLLQGPLALRNI--TDTGFKLLL 1115
             A++     +  L   + FL     L SVL       G + G LA+  I      F+   
Sbjct: 853  NALT--CRSQTKLIFEIGFLRNHMFLYSVL-------GSILGQLAVIYIPPLQRVFQTEN 903

Query: 1116 LGLVTLNFV-----GAFMLESVLDQCLPACLRRLRPKR 1148
            LG + L F+       F+L  +L  C   C     PKR
Sbjct: 904  LGALDLLFLTGLASSVFILSELLKLCEKYC---CSPKR 938


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
          Length = 1198

 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 117/571 (20%), Positives = 225/571 (39%), Gaps = 77/571 (13%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 400  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 459

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V    G      +P+P  +     +  L    A++    T +  P      
Sbjct: 460  TTNRMTV--VQAYVGDVHYKEIPDPSSINT-KTMELLINAIAINSAYTTKILPP------ 510

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMS 633
            E  G  L  +    +  G     +     +EP    M E      +   + F+S  + MS
Sbjct: 511  EKEG-ALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEE----KLYKVYTFNSVRKSMS 565

Query: 634  VVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAAGY 680
             V+  P  +    Y KG+ E+V   C              P        ++++     G 
Sbjct: 566  TVIKLPDESF-RMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGL 624

Query: 681  RVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIR 740
            R + +A +  P+ P  +   +   + +  +L+ + ++ + + ++P+    I+  +R  I 
Sbjct: 625  RTICVAYRDFPSSPEPDWDNE---NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGIT 681

Query: 741  AVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKD 800
              MVTGDN+ TA  +A  CG++ P E  + +      R        +  E    +     
Sbjct: 682  VRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI----- 736

Query: 801  PDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCE 860
                        P+ R LA S PT     KH        LV+G + +    +++      
Sbjct: 737  -----------WPKLRVLARSSPT----DKH-------TLVKGIIDSTHTEQRQV----- 769

Query: 861  LQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRC 920
                   V + GDG ND  ALK ADVG ++  A   V    +  + + +    +++    
Sbjct: 770  -------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMW 822

Query: 921  SLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAVLMSR 975
              +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  ++ ++ 
Sbjct: 823  GRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALAT 882

Query: 976  TGPALVLGRVRPPGALLSVPVLSSLLLQMVL 1006
              P   L   +P G   + P++S  +++ +L
Sbjct: 883  EPPTETLLLRKPYGR--NKPLISRTMMKNIL 911



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 7/96 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   +  +E+V GD +  
Sbjct: 162 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVVR-AGQVVQIPVAEIVVGD-IAQ 215

Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350
            + G L+P D   + G +  ++ESSLTGES  V K+
Sbjct: 216 VKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS 251


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
            sapiens]
          Length = 1220

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 133/621 (21%), Positives = 246/621 (39%), Gaps = 92/621 (14%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 419  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 478

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V    G      +P P  L    +L  L    +++    T +  P      
Sbjct: 479  TTNRMTV--VQSYLGDTHYKEIPAPSAL-TPKILDLLVHAISINSAYTTKILPP------ 529

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQ--LQAMEEPPVPVSVLHR-FPFSSALQ 630
                   E+E A     G +    +   + + +   Q + E  +P   L++ + F+S  +
Sbjct: 530  -------EKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ-IPEDKLYKVYTFNSVRK 581

Query: 631  RMSVVVAWPGATQPEAYVKGSPELVAGLCN-------------PETVPTDFAQMLQSYTA 677
             MS V+  P       + KG+ E++   C              P        ++++    
Sbjct: 582  SMSTVIRMPDGGF-RLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMAC 640

Query: 678  AGYRVVALASKPLPTVPSLEAAQQLTRDT---VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G R + +A +         A Q+   D    V GDL+ + ++ + + ++P+    I+  
Sbjct: 641  DGLRTICIAYR------DFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKC 694

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794
            +R  I   MVTGDN+ TA  +A  CG++ P E  + +      R        +  E    
Sbjct: 695  QRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDK 754

Query: 795  VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854
            V                 P+ R LA S PT     KH        LV+G + +    +++
Sbjct: 755  V----------------WPKLRVLARSSPT----DKH-------TLVKGIIDSTTGEQRQ 787

Query: 855  TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMV 914
                         V + GDG ND  ALK ADVG ++  A   V    +  + + +    +
Sbjct: 788  V------------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSI 835

Query: 915  IREGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTV 969
            ++      +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  
Sbjct: 836  VKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFA 895

Query: 970  AVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGV-QLGGYF-LTLAQPWFVPL 1027
            ++ ++   P   L   +P G     P++S  +++ +L   V QL   F L      F  +
Sbjct: 896  SLALATEPPTESLLLRKPYGR--DKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDI 953

Query: 1028 NRTVAAPDNLPNYEN-TVVFS 1047
            +    AP + P  E+ T++F+
Sbjct: 954  DSGRNAPLHSPPSEHYTIIFN 974



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   V  + LV GD +  
Sbjct: 165 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-NGQLLQVPVAALVVGD-IAQ 218

Query: 316 PQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTA 351
            + G L+P D  L+ A +  ++ESSLTGES  V K+A
Sbjct: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSA 255


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
            sapiens]
          Length = 1173

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 133/621 (21%), Positives = 246/621 (39%), Gaps = 92/621 (14%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 419  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 478

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V    G      +P P  L    +L  L    +++    T +  P      
Sbjct: 479  TTNRMTV--VQSYLGDTHYKEIPAPSAL-TPKILDLLVHAISINSAYTTKILPP------ 529

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQ--LQAMEEPPVPVSVLHR-FPFSSALQ 630
                   E+E A     G +    +   + + +   Q + E  +P   L++ + F+S  +
Sbjct: 530  -------EKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ-IPEDKLYKVYTFNSVRK 581

Query: 631  RMSVVVAWPGATQPEAYVKGSPELVAGLCN-------------PETVPTDFAQMLQSYTA 677
             MS V+  P       + KG+ E++   C              P        ++++    
Sbjct: 582  SMSTVIRMPDGGF-RLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMAC 640

Query: 678  AGYRVVALASKPLPTVPSLEAAQQLTRDT---VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G R + +A +         A Q+   D    V GDL+ + ++ + + ++P+    I+  
Sbjct: 641  DGLRTICIAYR------DFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKC 694

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794
            +R  I   MVTGDN+ TA  +A  CG++ P E  + +      R        +  E    
Sbjct: 695  QRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDK 754

Query: 795  VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854
            V                 P+ R LA S PT     KH        LV+G + +    +++
Sbjct: 755  V----------------WPKLRVLARSSPT----DKH-------TLVKGIIDSTTGEQRQ 787

Query: 855  TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMV 914
                         V + GDG ND  ALK ADVG ++  A   V    +  + + +    +
Sbjct: 788  V------------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSI 835

Query: 915  IREGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTV 969
            ++      +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  
Sbjct: 836  VKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFA 895

Query: 970  AVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGV-QLGGYF-LTLAQPWFVPL 1027
            ++ ++   P   L   +P G     P++S  +++ +L   V QL   F L      F  +
Sbjct: 896  SLALATEPPTESLLLRKPYGR--DKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDI 953

Query: 1028 NRTVAAPDNLPNYEN-TVVFS 1047
            +    AP + P  E+ T++F+
Sbjct: 954  DSGRNAPLHSPPSEHYTIIFN 974



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   V  + LV GD +  
Sbjct: 165 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-NGQLLQVPVAALVVGD-IAQ 218

Query: 316 PQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTA 351
            + G L+P D  L+ A +  ++ESSLTGES  V K+A
Sbjct: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSA 255


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+ +   G   ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
            +T+         + Q      +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831
              + +  Q  S E +       ++ +  P  A  Y   P    RH              
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624

Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891
                                 K +++  LQK    V M GDG ND  ALKAAD+G+++ 
Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662

Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946
           Q    V       +      + +   I EG+   +   +F  F+     +    IS+  L
Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722

Query: 947 YTINTNLGDLQFLAIDLVI 965
                 L  +Q L I++++
Sbjct: 723 MNFPNPLNAMQILWINIIM 741


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+ +   G   ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
            +T+         + Q      +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831
              + +  Q  S E +       ++ +  P  A  Y   P    RH              
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624

Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891
                                 K +++  LQK    V M GDG ND  ALKAAD+G+++ 
Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662

Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946
           Q    V       +      + +   I EG+   +   +F  F+     +    IS+  L
Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722

Query: 947 YTINTNLGDLQFLAIDLVI 965
                 L  +Q L I++++
Sbjct: 723 MNFPNPLNAMQILWINIIM 741


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+ +   G   ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
            +T+         + Q      +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831
              + +  Q  S E +       ++ +  P  A  Y   P    RH              
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624

Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891
                                 K +++  LQK    V M GDG ND  ALKAAD+G+++ 
Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662

Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946
           Q    V       +      + +   I EG+   +   +F  F+     +    IS+  L
Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722

Query: 947 YTINTNLGDLQFLAIDLVI 965
                 L  +Q L I++++
Sbjct: 723 MNFPNPLNAMQILWINIIM 741


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+ +   G   ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
            +T+         + Q      +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831
              + +  Q  S E +       ++ +  P  A  Y   P    RH              
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624

Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891
                                 K +++  LQK    V M GDG ND  ALKAAD+G+++ 
Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662

Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946
           Q    V       +      + +   I EG+   +   +F  F+     +    IS+  L
Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722

Query: 947 YTINTNLGDLQFLAIDLVI 965
                 L  +Q L I++++
Sbjct: 723 MNFPNPLNAMQILWINIIM 741


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
            sapiens]
          Length = 1176

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 132/619 (21%), Positives = 252/619 (40%), Gaps = 87/619 (14%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 421  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V     +     VPEP  +P   +L  L T  +++    + +  P      
Sbjct: 481  TMNRMTV--VQAYINEKHYKKVPEPEAIPPN-ILSYLVTGISVNCAYTSKILPP------ 531

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAME-EPPVPVSVLHR-FPFSSALQR 631
                   E+E       G +    +   L + +    +    +P   L++ + F+S  + 
Sbjct: 532  -------EKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKS 584

Query: 632  MSVVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAA 678
            MS V+     +    + KG+ E++   C              P         +++   + 
Sbjct: 585  MSTVLKNSDGSY-RIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643

Query: 679  GYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTR 738
            G R + LA +  P     E       D V G L+ + ++ + + ++P+    I+  +R  
Sbjct: 644  GLRTICLAFRDFPAGEP-EPEWDNENDIVTG-LTCIAVVGIEDPVRPEVPDAIKKCQRAG 701

Query: 739  IRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGV 798
            I   MVTGDN+ TA  +A  CG++ P E                  +FL +E       +
Sbjct: 702  ITVRMVTGDNINTARAIATKCGILHPGE------------------DFLCLEGKDFNRRI 743

Query: 799  K-DPDQAASYTVEPD-PRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856
            + +  +     ++   P+ R LA S PT     KH        LV+G + + ++ +++  
Sbjct: 744  RNEKGEIEQERIDKIWPKLRVLARSSPTD----KH-------TLVKGIIDSTVSDQRQV- 791

Query: 857  LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916
                       V + GDG ND  ALK ADVG ++  A   V    +  + + +    +++
Sbjct: 792  -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840

Query: 917  EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971
                  +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  ++
Sbjct: 841  AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900

Query: 972  LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTG-VQLGGYF-LTLAQPWFVPLNR 1029
             ++   P   L   +P G   + P++S  +++ +L     QL   F L  A   F  ++ 
Sbjct: 901  ALATEPPTESLLLRKPYGR--NKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDS 958

Query: 1030 TVAAPDNLPNYEN-TVVFS 1047
               AP + P  E+ T+VF+
Sbjct: 959  GRNAPLHAPPSEHYTIVFN 977



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 7/96 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R GG+   +  +++  GD +  
Sbjct: 164 VCVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-GGQVIQIPVADITVGD-IAQ 217

Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350
            + G L+P D  L+ G +  ++ESSLTGES  V K+
Sbjct: 218 VKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS 253


>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
            sapiens]
          Length = 1220

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 132/619 (21%), Positives = 252/619 (40%), Gaps = 87/619 (14%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 421  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V     +     VPEP  +P   +L  L T  +++    + +  P      
Sbjct: 481  TMNRMTV--VQAYINEKHYKKVPEPEAIPPN-ILSYLVTGISVNCAYTSKILPP------ 531

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAME-EPPVPVSVLHR-FPFSSALQR 631
                   E+E       G +    +   L + +    +    +P   L++ + F+S  + 
Sbjct: 532  -------EKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKS 584

Query: 632  MSVVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAA 678
            MS V+     +    + KG+ E++   C              P         +++   + 
Sbjct: 585  MSTVLKNSDGSY-RIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643

Query: 679  GYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTR 738
            G R + LA +  P     E       D V G L+ + ++ + + ++P+    I+  +R  
Sbjct: 644  GLRTICLAFRDFPAGEP-EPEWDNENDIVTG-LTCIAVVGIEDPVRPEVPDAIKKCQRAG 701

Query: 739  IRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGV 798
            I   MVTGDN+ TA  +A  CG++ P E                  +FL +E       +
Sbjct: 702  ITVRMVTGDNINTARAIATKCGILHPGE------------------DFLCLEGKDFNRRI 743

Query: 799  K-DPDQAASYTVEPD-PRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856
            + +  +     ++   P+ R LA S PT     KH        LV+G + + ++ +++  
Sbjct: 744  RNEKGEIEQERIDKIWPKLRVLARSSPTD----KH-------TLVKGIIDSTVSDQRQV- 791

Query: 857  LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916
                       V + GDG ND  ALK ADVG ++  A   V    +  + + +    +++
Sbjct: 792  -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840

Query: 917  EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971
                  +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  ++
Sbjct: 841  AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900

Query: 972  LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTG-VQLGGYF-LTLAQPWFVPLNR 1029
             ++   P   L   +P G   + P++S  +++ +L     QL   F L  A   F  ++ 
Sbjct: 901  ALATEPPTESLLLRKPYGR--NKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDS 958

Query: 1030 TVAAPDNLPNYEN-TVVFS 1047
               AP + P  E+ T+VF+
Sbjct: 959  GRNAPLHAPPSEHYTIVFN 977



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 7/96 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R GG+   +  +++  GD +  
Sbjct: 164 VCVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-GGQVIQIPVADITVGD-IAQ 217

Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350
            + G L+P D  L+ G +  ++ESSLTGES  V K+
Sbjct: 218 VKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS 253


>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
          Length = 1426

 Score = 87.0 bits (214), Expect = 9e-17
 Identities = 87/323 (26%), Positives = 139/323 (43%), Gaps = 48/323 (14%)

Query: 614  PVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGL---CNPETVPTDFAQ 670
            P+   +LH  PF S  +RMSVVV  P + Q   Y KG+  ++  L    +P+    +  Q
Sbjct: 761  PLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQ 820

Query: 671  M---------LQSYTAAGYRVVALASKPLPTVP-------------SLEAAQQLTRDT-- 706
            M         L  Y   G R + +A K +                 S++  ++L  ++  
Sbjct: 821  MIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAM 880

Query: 707  -VEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQ 765
             +E  L+LLG   + + L+      I+AL +  I+  M+TGD  +TAV +A  C ++ P 
Sbjct: 881  RLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPD 940

Query: 766  EHLIIVHATHPER-GQPASLEFLPMESPTAVNGVKDPDQAA---SYTVEPDPRS----RH 817
            + L I++    +  G   S     ++  T       P+Q +        P PR       
Sbjct: 941  DKLFILNTQSKDACGMLMSTILKELQKKTQAL----PEQVSLSEDLLQPPVPRDSGLRAG 996

Query: 818  LALSGPTFGI-----IVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQK-LQYCVGMC 871
            L ++G T        + K F +L      Q  V  R  P QK+E+V  ++  LQ      
Sbjct: 997  LIITGKTLEFALQESLQKQFLELTS--WCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAI 1054

Query: 872  GDGANDCGALKAADVGISLSQAE 894
            GDGAND   ++ AD+GI +S  E
Sbjct: 1055 GDGANDVSMIQVADIGIGVSGQE 1077


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
            sapiens]
          Length = 1170

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 121/575 (21%), Positives = 234/575 (40%), Gaps = 86/575 (14%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 411  IIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 470

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V+       QA++  +   R++P   +         L ++ D  V         
Sbjct: 471  TMNRMTVV-------QAYIGGI-HYRQIPSPDVF--------LPKVLDLIVNGISINSAY 514

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWE--PQLQAMEEPPVPVSVLHR-FPFSSALQ 630
             S     E+E       G +    +   + +     QA+    VP   L++ + F+S  +
Sbjct: 515  TSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE-VPEEKLYKVYTFNSVRK 573

Query: 631  RMSVVVAWPGATQPEAYVKGSPELVAGLCNP------ETVP------TDFAQ-MLQSYTA 677
             MS V+  P       Y KG+ E++   CN       E VP       D  + +++    
Sbjct: 574  SMSTVIRNPNGGF-RMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632

Query: 678  AGYRVVALASKPLP-TVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRR 736
             G R + +A +    T PS +   ++  +     L+ + ++ + + ++P+    I   ++
Sbjct: 633  DGLRTICIAYRDFDDTEPSWDNENEILTE-----LTCIAVVGIEDPVRPEVPDAIAKCKQ 687

Query: 737  TRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVN 796
              I   MVTGDN+ TA  +A  CG++ P +  + +      R                 N
Sbjct: 688  AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNR--------------LIRN 733

Query: 797  GVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856
               + +Q     + P  + R LA S PT     KH        LV+G + + +   ++  
Sbjct: 734  EKGEVEQEKLDKIWP--KLRVLARSSPTD----KH-------TLVKGIIDSTVGEHRQV- 779

Query: 857  LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916
                       V + GDG ND  ALK ADVG ++  A   V    +  + + +    +++
Sbjct: 780  -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 828

Query: 917  EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971
                  +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  ++
Sbjct: 829  AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL 888

Query: 972  LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVL 1006
             ++   P   L + RP G   + P++S  +++ +L
Sbjct: 889  ALATEPPTESLLKRRPYGR--NKPLISRTMMKNIL 921



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 271 YKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330
           +   KQ + L+  ++   +  + R  G+   +  +E+V GD +   + G L+P D  L+ 
Sbjct: 171 WSKEKQFRGLQCRIEQEQKFSIIR-NGQLIQLPVAEIVVGD-IAQVKYGDLLPADGILIQ 228

Query: 331 G-ECMVNESSLTGESIPVLKT 350
           G +  ++ESSLTGES  V K+
Sbjct: 229 GNDLKIDESSLTGESDHVKKS 249


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
            sapiens]
          Length = 1205

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 121/575 (21%), Positives = 234/575 (40%), Gaps = 86/575 (14%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 411  IIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 470

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V+       QA++  +   R++P   +         L ++ D  V         
Sbjct: 471  TMNRMTVV-------QAYIGGI-HYRQIPSPDVF--------LPKVLDLIVNGISINSAY 514

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWE--PQLQAMEEPPVPVSVLHR-FPFSSALQ 630
             S     E+E       G +    +   + +     QA+    VP   L++ + F+S  +
Sbjct: 515  TSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE-VPEEKLYKVYTFNSVRK 573

Query: 631  RMSVVVAWPGATQPEAYVKGSPELVAGLCNP------ETVP------TDFAQ-MLQSYTA 677
             MS V+  P       Y KG+ E++   CN       E VP       D  + +++    
Sbjct: 574  SMSTVIRNPNGGF-RMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632

Query: 678  AGYRVVALASKPLP-TVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRR 736
             G R + +A +    T PS +   ++  +     L+ + ++ + + ++P+    I   ++
Sbjct: 633  DGLRTICIAYRDFDDTEPSWDNENEILTE-----LTCIAVVGIEDPVRPEVPDAIAKCKQ 687

Query: 737  TRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVN 796
              I   MVTGDN+ TA  +A  CG++ P +  + +      R                 N
Sbjct: 688  AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNR--------------LIRN 733

Query: 797  GVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856
               + +Q     + P  + R LA S PT     KH        LV+G + + +   ++  
Sbjct: 734  EKGEVEQEKLDKIWP--KLRVLARSSPTD----KH-------TLVKGIIDSTVGEHRQV- 779

Query: 857  LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916
                       V + GDG ND  ALK ADVG ++  A   V    +  + + +    +++
Sbjct: 780  -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 828

Query: 917  EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971
                  +   S+ K++        ++V++ +     T ++ L  +Q L ++L++ T  ++
Sbjct: 829  AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL 888

Query: 972  LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVL 1006
             ++   P   L + RP G   + P++S  +++ +L
Sbjct: 889  ALATEPPTESLLKRRPYGR--NKPLISRTMMKNIL 921



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 271 YKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330
           +   KQ + L+  ++   +  + R  G+   +  +E+V GD +   + G L+P D  L+ 
Sbjct: 171 WSKEKQFRGLQCRIEQEQKFSIIR-NGQLIQLPVAEIVVGD-IAQVKYGDLLPADGILIQ 228

Query: 331 G-ECMVNESSLTGESIPVLKT 350
           G +  ++ESSLTGES  V K+
Sbjct: 229 GNDLKIDESSLTGESDHVKKS 249


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++   P    +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%)

Query: 846  FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903
            FAR+ P  K+ +V  LQ       M GDG ND  ALK A++GI++    A A   +    
Sbjct: 676  FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735

Query: 904  SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961
            S  +   +   + EGR          +Y+   ++ + + + +  +  +   L  +Q L +
Sbjct: 736  SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795

Query: 962  DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021
            +LV     A  +    P L +    P        ++S  L    L  GV +G   +  A 
Sbjct: 796  NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853

Query: 1022 PWFV 1025
             WFV
Sbjct: 854  WWFV 857


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++   P    +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%)

Query: 846  FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903
            FAR+ P  K+ +V  LQ       M GDG ND  ALK A++GI++    A A   +    
Sbjct: 676  FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735

Query: 904  SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961
            S  +   +   + EGR          +Y+   ++ + + + +  +  +   L  +Q L +
Sbjct: 736  SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795

Query: 962  DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021
            +LV     A  +    P L +    P        ++S  L    L  GV +G   +  A 
Sbjct: 796  NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853

Query: 1022 PWFV 1025
             WFV
Sbjct: 854  WWFV 857


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++   P    +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%)

Query: 846  FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903
            FAR+ P  K+ +V  LQ       M GDG ND  ALK A++GI++    A A   +    
Sbjct: 676  FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735

Query: 904  SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961
            S  +   +   + EGR          +Y+   ++ + + + +  +  +   L  +Q L +
Sbjct: 736  SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795

Query: 962  DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021
            +LV     A  +    P L +    P        ++S  L    L  GV +G   +  A 
Sbjct: 796  NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853

Query: 1022 PWFV 1025
             WFV
Sbjct: 854  WWFV 857


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++   P    +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%)

Query: 846  FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903
            FAR+ P  K+ +V  LQ       M GDG ND  ALK A++GI++    A A   +    
Sbjct: 676  FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735

Query: 904  SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961
            S  +   +   + EGR          +Y+   ++ + + + +  +  +   L  +Q L +
Sbjct: 736  SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795

Query: 962  DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021
            +LV     A  +    P L +    P        ++S  L    L  GV +G   +  A 
Sbjct: 796  NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853

Query: 1022 PWFV 1025
             WFV
Sbjct: 854  WWFV 857


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,926,801
Number of Sequences: 37866
Number of extensions: 2156170
Number of successful extensions: 5454
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 5153
Number of HSP's gapped (non-prelim): 197
length of query: 1175
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1062
effective length of database: 13,968,660
effective search space: 14834716920
effective search space used: 14834716920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.