BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] (1175 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 2336 0.0 gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 2330 0.0 gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 2040 0.0 gi|148839292 ATPase type 13A3 [Homo sapiens] 844 0.0 gi|66932949 ATPase type 13A4 [Homo sapiens] 765 0.0 gi|66730421 ATPase type 13A5 [Homo sapiens] 763 0.0 gi|170016077 ATPase type 13A1 [Homo sapiens] 261 4e-69 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 123 1e-27 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 123 1e-27 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 123 1e-27 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 112 3e-24 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 105 2e-22 gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 97 1e-19 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 97 1e-19 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 95 4e-19 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 93 1e-18 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 93 1e-18 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 92 3e-18 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 92 3e-18 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 92 3e-18 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 92 3e-18 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 91 5e-18 gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 91 5e-18 gi|222352161 ATPase, class V, type 10D [Homo sapiens] 87 9e-17 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 85 4e-16 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 85 4e-16 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 80 1e-14 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 80 1e-14 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 80 1e-14 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 80 1e-14 >gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] Length = 1175 Score = 2336 bits (6054), Expect = 0.0 Identities = 1175/1175 (100%), Positives = 1175/1175 (100%) Query: 1 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI Sbjct: 1 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60 Query: 61 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS Sbjct: 61 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120 Query: 121 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV Sbjct: 121 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180 Query: 181 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA Sbjct: 181 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240 Query: 241 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE Sbjct: 241 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300 Query: 301 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC Sbjct: 301 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360 Query: 361 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS Sbjct: 361 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420 Query: 421 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ Sbjct: 421 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480 Query: 481 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR Sbjct: 481 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540 Query: 541 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP Sbjct: 541 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600 Query: 601 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN Sbjct: 601 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660 Query: 661 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR Sbjct: 661 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720 Query: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ Sbjct: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780 Query: 781 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL Sbjct: 781 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840 Query: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP Sbjct: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900 Query: 901 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA Sbjct: 901 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960 Query: 961 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA Sbjct: 961 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020 Query: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1080 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL Sbjct: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1080 Query: 1081 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1140 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC Sbjct: 1081 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1140 Query: 1141 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1175 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR Sbjct: 1141 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1175 >gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] Length = 1180 Score = 2330 bits (6038), Expect = 0.0 Identities = 1175/1180 (99%), Positives = 1175/1180 (99%), Gaps = 5/1180 (0%) Query: 1 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI Sbjct: 1 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60 Query: 61 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS Sbjct: 61 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120 Query: 121 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ 175 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA KRVLRYYLFQGQRYIWIETQQ Sbjct: 121 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 180 Query: 176 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 235 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY Sbjct: 181 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 240 Query: 236 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 295 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP Sbjct: 241 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 300 Query: 296 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 355 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG Sbjct: 301 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 360 Query: 356 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 415 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK Sbjct: 361 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 420 Query: 416 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 475 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC Sbjct: 421 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 480 Query: 476 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 535 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV Sbjct: 481 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 540 Query: 536 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 595 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL Sbjct: 541 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 600 Query: 596 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 655 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV Sbjct: 601 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 660 Query: 656 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 715 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG Sbjct: 661 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 720 Query: 716 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 775 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH Sbjct: 721 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 780 Query: 776 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 835 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL Sbjct: 781 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 840 Query: 836 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 895 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA Sbjct: 841 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 900 Query: 896 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 955 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD Sbjct: 901 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 960 Query: 956 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 1015 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY Sbjct: 961 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 1020 Query: 1016 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1075 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP Sbjct: 1021 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1080 Query: 1076 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ 1135 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ Sbjct: 1081 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ 1140 Query: 1136 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1175 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR Sbjct: 1141 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1180 >gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] Length = 1158 Score = 2040 bits (5284), Expect = 0.0 Identities = 1034/1073 (96%), Positives = 1034/1073 (96%), Gaps = 39/1073 (3%) Query: 1 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI Sbjct: 1 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60 Query: 61 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS Sbjct: 61 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120 Query: 121 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV Sbjct: 121 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180 Query: 181 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA Sbjct: 181 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240 Query: 241 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE Sbjct: 241 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300 Query: 301 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC Sbjct: 301 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360 Query: 361 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS Sbjct: 361 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420 Query: 421 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ Sbjct: 421 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480 Query: 481 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR Sbjct: 481 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540 Query: 541 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP Sbjct: 541 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600 Query: 601 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN Sbjct: 601 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660 Query: 661 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR Sbjct: 661 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720 Query: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ Sbjct: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780 Query: 781 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840 PASLEFLPMESPTAVNGV KVL Sbjct: 781 PASLEFLPMESPTAVNGV---------------------------------------KVL 801 Query: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP Sbjct: 802 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 861 Query: 901 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA Sbjct: 862 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 921 Query: 961 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA Sbjct: 922 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 981 Query: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1073 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN Sbjct: 982 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034 >gi|148839292 ATPase type 13A3 [Homo sapiens] Length = 1226 Score = 844 bits (2181), Expect = 0.0 Identities = 494/1196 (41%), Positives = 704/1196 (58%), Gaps = 68/1196 (5%) Query: 35 VRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD 94 + + GY S W++ + V G LLL W P W V+ + E +++ D Sbjct: 17 MEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTD 76 Query: 95 KEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHK-SEE 153 E W F +++ ++ E SP+S + + AV + ++ ++ K S+ Sbjct: 77 -EFKMW--FCAKIRVLSL-ETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQT 132 Query: 154 AKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYG 212 + +RY+ +Y W +T F + LD G SC ++ GL+ RK +YG Sbjct: 133 ESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYG 192 Query: 213 PNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYK 272 N I++ V S +LL+ E LNP+Y FQ FS+ LW D YY+YAL I ++S +SI SLY Sbjct: 193 VNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYS 252 Query: 273 TRKQSQTLRDMVKL--SMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330 RKQ L DMV ++RV VCR E E + S++LVPGD +V+P G +MPCDA L+ Sbjct: 253 IRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN 312 Query: 331 GECMVNESSLTGESIPVLKTALP------EGLGP--YCAETHRRHTLFCGTLILQARAYV 382 G C+VNES LTGES+PV KT LP +G+G Y ETH+RHTLFCGT ++Q R Y Sbjct: 313 GTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYT 372 Query: 383 GPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFIL 442 G V A+V RTGF T+KG LV SIL+P+P +FK Y+ + F+ L +A +G IY+I Sbjct: 373 GELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINS 432 Query: 443 YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKL 502 N V + I+I +LD++T+ VPPALPAAMT +YAQ RL++ GIFCI P RIN+ G+L Sbjct: 433 ILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQL 492 Query: 503 QLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPR----RLPVGPLLRALATCHALSR 558 LVCFDKTGTLTEDGLD+ G+ ++ FL PE L + +ATCH+L++ Sbjct: 493 NLVCFDKTGTLTEDGLDLWGIQRVENARFLS--PEENVCNEMLVKSQFVACMATCHSLTK 550 Query: 559 LQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL-AVMRPP---------LWEPQLQ 608 ++ GDP+DLKM E+ GW+LEE ++A +++ V+RPP +++ Sbjct: 551 IEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEME 610 Query: 609 AMEEPPV-PVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPETVPTD 667 E P + ++ +FPFSSALQRMSVV G + +AY+KG+PE +AGLC PETVP D Sbjct: 611 LFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVD 670 Query: 668 FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQT 727 F +L+ +T G+RV+ALA + L + + Q ++RD +E ++ +GL++M+N LK +T Sbjct: 671 FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQET 730 Query: 728 TPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFL 787 V++ L + IR VMVTGD++ TAV+VAR CGM+ PQ+ +II A P+ G+ A + + Sbjct: 731 PAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWH 790 Query: 788 PMES------PTAVNGVKDPDQAASYTVEPDPRSR-HLALSGPTFGIIVKHFPKLLPKVL 840 +S P+A++ P + ++E +R H A++G +F +I++HF L+PK++ Sbjct: 791 YADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLM 850 Query: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900 + GTVFARMAP+QKT+L+ LQ + Y VGMCGDGANDCGALK A GISLS+ EASV SP Sbjct: 851 LHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASP 910 Query: 901 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960 FTS SI CVP +IREGR +L TSF VFK+MALYS+ Q+ SV +LY+I +NLGD QFL Sbjct: 911 FTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLF 970 Query: 961 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020 IDL I V MS L RPP L+S +L S+L Q+++ G Q G+F Sbjct: 971 IDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQ 1030 Query: 1021 QPWFVPL---------------------NRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1059 QPW+ N T N+ NYENT VF +SSFQYLI+A A Sbjct: 1031 QPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLIVAIA 1090 Query: 1060 VSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLV 1119 SKG PFR+P Y N F+ ++ L ++ ++L P + +++ +L +V Sbjct: 1091 FSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWRVTMLIIV 1150 Query: 1120 TLNFVGAFMLESVLDQ----CLPACLRRLRPKRASKKRFKQLERELAEQP-WPPLP 1170 +N + +E +D+ CLP L K+ K ++ L +EL P WPP P Sbjct: 1151 LVNAFVSITVEESVDRWGKCCLPWALG--CRKKTPKAKYMYLAQELLVDPEWPPKP 1204 >gi|66932949 ATPase type 13A4 [Homo sapiens] Length = 1196 Score = 765 bits (1976), Expect = 0.0 Identities = 468/1162 (40%), Positives = 675/1162 (58%), Gaps = 89/1162 (7%) Query: 59 GIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDK-EDSSWQLFTVQVQTEAIGEGSL 117 GI L+F W+P W V PC+L A+T+++ D+ + SW+ + + A+ Sbjct: 44 GILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKK-VIWIYLSALN---- 98 Query: 118 EPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRV---LRYYLFQGQRYIWIETQ 174 +A G P+ + + ++ +R Q RY+W + Sbjct: 99 --------------SAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLE 144 Query: 175 QAFYQVSLLDHGRSCDDVHRS-RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233 F ++ L+ S +H+ GL+ ++Q +R+ I GPN I + V +LL+ E LN Sbjct: 145 GQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLN 204 Query: 234 PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKL--SMRVC 291 P+Y FQ FS+ LW ++ Y YA I ++S ISI L++Y R+QS L +V+ S+ V Sbjct: 205 PFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVS 264 Query: 292 VC-RPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKT 350 VC R G +E ++S LVPGD L+L LMPCDA L+ G C+V+E LTGESIPV KT Sbjct: 265 VCGRKAGVQE-LESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKT 323 Query: 351 ALP--EGLGPYCAET---HRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSS 405 LP + P+ ++ ++RH LFCGT ++QA+A V AVV +TGF TAKG LV S Sbjct: 324 PLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRS 383 Query: 406 ILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVP 465 IL+P+P+NF+ Y+ +++F+ L A +G IY++ + + P E+V +ALD++T+ VP Sbjct: 384 ILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVP 443 Query: 466 PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVP 525 PALPAA+T +YAQ RL+++GIFCI P RIN+ G+L LVCFDKTGTLT DGLD+ GVV Sbjct: 444 PALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVS 503 Query: 526 LKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEE 583 F + + LP GPL A+A+CH+L L T GDP+DLKM E+T W Sbjct: 504 CDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW----- 558 Query: 584 PAADSAFGTQVLAVMRPP----LWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWP 639 + AF + P + +P A + P +++LH+FPFSSALQRM+V+V Sbjct: 559 ---EMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEM 615 Query: 640 GATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAA 699 G + A++KG+PE VA C PETVPT F LQ YT G+RV+ALA K L A Sbjct: 616 GGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---HHA 671 Query: 700 QQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGC 759 LTR+TVE DL LGLL++ N LK +T PV++ L RIR VM+TGDNLQTA+TVAR Sbjct: 672 TTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKS 731 Query: 760 GMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAV------NGVKDPDQAASYTVEPDP 813 GMV+ + +I++ A AS+ + +E + N + D+ + E Sbjct: 732 GMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREG-- 789 Query: 814 RSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGD 873 S H AL+G +F +I +HF LLPK+L+ GT+FARM+P QK+ LV E QKL Y VGMCGD Sbjct: 790 -SYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGD 848 Query: 874 GANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMA 933 GANDCGALK A VGISLS+ EASV SPFTS +IECVP +I+EGR +L TSF +FKYMA Sbjct: 849 GANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMA 908 Query: 934 LYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLS 993 LYS+ Q++ VL+LY +L + QFL DL ITT + V M+ G L RP G L+S Sbjct: 909 LYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLIS 968 Query: 994 VPVLSSLLLQMVLVTGVQLGGYFLTLAQPWF---------------VPLNRTVAAPDNL- 1037 P+L S++ ++L + + G+ L QPW+ L + AP+ + Sbjct: 969 PPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKME 1028 Query: 1038 -----PNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVL 1092 ++ENT V+ L + + +A SKG PFR+P YTN F++ L + V + ++ Sbjct: 1029 SNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILF 1088 Query: 1093 --VPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVL--DQCLPACLRRLRPKR 1148 +P L + L T ++ ++ +++LNF+ + + E + ++ L ++R + Sbjct: 1089 ADIPELYRRLDLL--CTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIKRCFGYQ 1146 Query: 1149 ASKKRFKQLERELAEQP-WPPL 1169 SK +++ +R+LA P WPPL Sbjct: 1147 -SKSQYRIWQRDLANDPSWPPL 1167 >gi|66730421 ATPase type 13A5 [Homo sapiens] Length = 1218 Score = 763 bits (1970), Expect = 0.0 Identities = 470/1169 (40%), Positives = 659/1169 (56%), Gaps = 104/1169 (8%) Query: 62 LLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD-------KEDSSWQLFTVQVQTEAIGE 114 LL+F W+P W V PC L A+T+++ D K+ L T++ E Sbjct: 48 LLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWE 107 Query: 115 GSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQ 174 SL S +QA + + + LR Q RY+W + + Sbjct: 108 ESLVADRHSVI----NQALI------------------KPELKLRCMEVQKIRYVWNDLE 145 Query: 175 QAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233 + F +V LL+ SC D+H++ GL+ ++Q VR+ + GPN I + ++ +LLV + LN Sbjct: 146 KRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLN 205 Query: 234 PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMV----KLSMR 289 P+Y FQAF++ LWL+ Y Y++ I +++ ISI LS+Y R+QS L ++V K+ + Sbjct: 206 PFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVT 265 Query: 290 VCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLK 349 + V G EE ++S LVPGD L+LP + L PCDA L+ G C+VNE LTGESIPV K Sbjct: 266 IIVKDKGLEE--LESRLLVPGDILILPGKFSL-PCDAVLIDGSCVVNEGMLTGESIPVTK 322 Query: 350 TALP--EGLGPY---CAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVS 404 T LP E P+ E +R+H LFCGT ++Q + V AVV +TG+ TAKG LV Sbjct: 323 TPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVR 382 Query: 405 SILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVV 464 SIL+PRP+NFK Y + KF+ L+ L ++G Y++ + + VP + V AL L+TV V Sbjct: 383 SILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTV 442 Query: 465 PPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVV 524 PP LPAA+T+ +YAQ RL+++ IFCI P RIN+ G++ LVCFDKTGTLTEDGLD+ G V Sbjct: 443 PPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV 502 Query: 525 PLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEE 582 P F + +P PL A+A+CH+L L T GDP+DLKM E T W +E+ Sbjct: 503 PTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMED 562 Query: 583 EPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGAT 642 FGT V +++P +A + P + L +FPFSS+LQRMSV+ G Sbjct: 563 CIVDSCKFGTSVSNIIKPGP-----KASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGEN 617 Query: 643 QPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQL 702 Y+KG+PE+VA C ETVP +F Q L+SYT G+RV+ALA K L + +L + L Sbjct: 618 HFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLK-MGNLSEVEHL 676 Query: 703 TRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMV 762 R+ VE +L+ LGLL+M N LK +T V++ L RIR VM+TGDNLQTA+TVA+ M+ Sbjct: 677 AREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMI 736 Query: 763 APQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSR---HLA 819 P +IIV A PE PAS+ + +E+ G K+ + P H A Sbjct: 737 PPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFA 796 Query: 820 LSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 879 +SG ++ +I +HF LLPK+LV GTVFARM+P QK+ L+ E QKL Y VGMCGDGANDCG Sbjct: 797 MSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCG 856 Query: 880 ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 939 ALKAA GISLS+ EASV SPFTS +I+CVP +IREGR +L +SF VFKY+ +Y + Q Sbjct: 857 ALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQ 916 Query: 940 FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 999 FIS L+LY G+ Q+L D+ IT V + MS T L RP G LLS P+L S Sbjct: 917 FISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLS 976 Query: 1000 LLLQMVLVTGVQLGGYFLTLAQPWF--------------------VPLNR-----TVAAP 1034 + L VQ+ + QPW+ V L R P Sbjct: 977 IFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIP 1036 Query: 1035 DNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPF----LVALALLSSVLV-- 1088 ++ ++E T ++ +++ Y+ +A SKG PFR+P+YTN F L AL L +L Sbjct: 1037 GSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSD 1096 Query: 1089 ------GLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLE-SVLDQCLPACL 1141 G+ L+P T T +++L+L + F AF +E S+L L Sbjct: 1097 FQVIYRGMELIP------------TITSWRVLILVVALTQFCVAFFVEDSILQNHELWLL 1144 Query: 1142 RRLRPKRASKKRFKQLERELAE-QPWPPL 1169 + SK +++ +++LAE WPP+ Sbjct: 1145 IKREFGFYSKSQYRTWQKKLAEDSTWPPI 1173 >gi|170016077 ATPase type 13A1 [Homo sapiens] Length = 1204 Score = 261 bits (666), Expect = 4e-69 Identities = 217/730 (29%), Positives = 355/730 (48%), Gaps = 83/730 (11%) Query: 193 HRSRHGLSLQDQMVRKAI--YGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADH 250 ++S G +D +R A +G N + V + +L + A P++ FQ F + LW D Sbjct: 203 YQSNRGFQ-EDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDE 261 Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEW--VDSSELV 308 Y++Y+ +F +S + + ++Q + + ++ K+ + + + +W + S E+V Sbjct: 262 YWYYS--VFTLSML-VAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIV 318 Query: 309 PGDCLVL---PQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPY----CA 361 PGD + + PQE L+PCD L+ G C+V+E+ LTGES+P +K + E L P Sbjct: 319 PGDIVSIGRSPQEN-LVPCDVLLLRGRCIVDEAMLTGESVPQMKEPI-EDLSPDRVLDLQ 376 Query: 362 ETHRRHTLFCGTLILQ----ARAYVG-----PHVLAVVTRTGFCTAKGGLVSSILHPRPI 412 R H +F GT ++Q +A G +A V RTGF T++G L+ +IL Sbjct: 377 ADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKR 436 Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL-----YRNRVPLNEIVIRALDLVTVVVPPA 467 + F+ L V A+ Y ++I RNR L + ++T VVPP Sbjct: 437 VTANNLETFIFILFLLVFAIAAAAY-VWIEGTKDPSRNRYKL---FLECTLILTSVVPPE 492 Query: 468 LPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLK 527 LP +++ + L + ++C P RI GK+++ CFDKTGTLT D L V GV L+ Sbjct: 493 LPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLR 552 Query: 528 -GQAFLPLVPEPRRLPVGPLLRALATCHALSRLQD-TPVGDPMDLKMVESTGWVL-EEEP 584 G+ P+ P RALA+CH+L +L D T VGDP++ M+ + W L ++E Sbjct: 553 DGKEVTPVSSIPVETH-----RALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEK 607 Query: 585 AADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQP 644 + TQ L + + RF F+SAL+RMSV+ ++ Sbjct: 608 VFPRSIKTQGLKIHQ----------------------RFHFASALKRMSVLASYEKLGST 645 Query: 645 E----AYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 700 + A VKG+PE + + + P D+ + + G RV+AL K L + + A+ Sbjct: 646 DLCYIAAVKGAPETLHSMFSQ--CPPDYHHIHTEISREGARVLALGYKELGHLTH-QQAR 702 Query: 701 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 760 ++ R+ +E L +G +V+ LK + VI+ ++ R VM+TGDN TA VA+ Sbjct: 703 EVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELH 762 Query: 761 MVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLAL 820 + LI+ P + E+ ++ + + +A + L L Sbjct: 763 FIEKAHTLIL----QPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYA-------LCL 811 Query: 821 SGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGA 880 +G + P+ L +++ VFAR+AP+QK ++ L++L Y MCGDG ND GA Sbjct: 812 TGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGA 871 Query: 881 LKAADVGISL 890 LK ADVG++L Sbjct: 872 LKHADVGVAL 881 Score = 82.4 bits (202), Expect = 2e-15 Identities = 70/261 (26%), Positives = 122/261 (46%), Gaps = 43/261 (16%) Query: 894 EASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNL 953 +AS+ +PFTS ++SI+C+ VI++GRC+L T+ +FK +AL +L S +LY Sbjct: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012 Query: 954 GDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLG 1013 D Q L++ + +SR+ P L R RP + ++ + +++LQ + Sbjct: 1013 SDFQATLQGLLLAGCF-LFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFV------- 1064 Query: 1014 GYFLTLA-------------QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAV 1060 +FL+L Q FV L + P+ N+ V+ ++ + A Sbjct: 1065 -HFLSLVYLYREAQARSPEKQEQFVDLYKEFE-----PSLVNSTVYIMAMAMQMATFAIN 1118 Query: 1061 SKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVP--------GLLQGPLALRNITDTGFK 1112 KG PF L N P + +LA+ ++GL+L GL+ P+ FK Sbjct: 1119 YKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVE--------FK 1170 Query: 1113 LLLLGLVTLNFVGAFMLESVL 1133 L++ ++ L+F A + + VL Sbjct: 1171 LVIAQVLLLDFCLALLADRVL 1191 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 123 bits (308), Expect = 1e-27 Identities = 212/911 (23%), Positives = 363/911 (39%), Gaps = 127/911 (13%) Query: 179 QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233 +VS+ DH S D++HR GL+ A GPN ++ P + + L Sbjct: 38 EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 96 Query: 234 PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274 F FS+ LW+ + A I ++S++ I C S Y+ Sbjct: 97 ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 152 Query: 275 KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333 K S+ + + + + GE+ +++ E+V GD LV + G +P D ++ A C Sbjct: 153 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 211 Query: 334 MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393 V+ SSLTGES P +T P+ ET R+ F T ++ A +V T Sbjct: 212 KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 261 Query: 394 GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449 G T G + ++S L PI + +H + + ++V LG + I L L Sbjct: 262 GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 318 Query: 450 NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509 E VI + ++ VP L A +TVC R+ R+ + + G +C DK Sbjct: 319 -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 377 Query: 510 TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569 TGTLT++ M V + + + AT ALSR+ + + Sbjct: 378 TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 432 Query: 570 LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629 + + +L+ A D++ + + E +++E + + PF+S Sbjct: 433 FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 486 Query: 630 QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676 + + P ++P+ +KG+PE + C+ E + F Sbjct: 487 KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 546 Query: 677 AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734 G RV+ LP E Q T D +L +GL+ M + + + Sbjct: 547 GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 606 Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794 R I+ +MVTGD+ TA +A+G G+++ ++E + Sbjct: 607 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE---------------TVEDIAARLNIP 651 Query: 795 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854 V+ V D A D + ++ I+K+ ++ VFAR +P+QK Sbjct: 652 VSQVNPRDAKACVVHGSDLKD----MTSEQLDDILKYHTEI---------VFARTSPQQK 698 Query: 855 TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----C 910 +V Q+ V + GDG ND ALK AD+G+++ A S VS + M ++ Sbjct: 699 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDDNFAS 757 Query: 911 VPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLV 964 + + EGR D K Y+LT I + I+ I LG + L IDL Sbjct: 758 IVTGVEEGRLIFDN----LKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLG 813 Query: 965 ITTTVAVLMSRTGPALVLGRVRP----PGALLSVPVLSSLLLQMVLVTGVQLGG---YFL 1017 A+ ++ + + +P L++ ++S Q+ ++ LGG YF+ Sbjct: 814 TDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQA--LGGFFTYFV 871 Query: 1018 TLAQPWFVPLN 1028 LA+ F+P++ Sbjct: 872 ILAENGFLPIH 882 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 123 bits (308), Expect = 1e-27 Identities = 212/911 (23%), Positives = 363/911 (39%), Gaps = 127/911 (13%) Query: 179 QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233 +VS+ DH S D++HR GL+ A GPN ++ P + + L Sbjct: 7 EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 65 Query: 234 PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274 F FS+ LW+ + A I ++S++ I C S Y+ Sbjct: 66 ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 121 Query: 275 KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333 K S+ + + + + GE+ +++ E+V GD LV + G +P D ++ A C Sbjct: 122 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 180 Query: 334 MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393 V+ SSLTGES P +T P+ ET R+ F T ++ A +V T Sbjct: 181 KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 230 Query: 394 GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449 G T G + ++S L PI + +H + + ++V LG + I L L Sbjct: 231 GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 287 Query: 450 NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509 E VI + ++ VP L A +TVC R+ R+ + + G +C DK Sbjct: 288 -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 346 Query: 510 TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569 TGTLT++ M V + + + AT ALSR+ + + Sbjct: 347 TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 401 Query: 570 LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629 + + +L+ A D++ + + E +++E + + PF+S Sbjct: 402 FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 455 Query: 630 QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676 + + P ++P+ +KG+PE + C+ E + F Sbjct: 456 KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 515 Query: 677 AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734 G RV+ LP E Q T D +L +GL+ M + + + Sbjct: 516 GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 575 Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794 R I+ +MVTGD+ TA +A+G G+++ ++E + Sbjct: 576 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE---------------TVEDIAARLNIP 620 Query: 795 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854 V+ V D A D + ++ I+K+ ++ VFAR +P+QK Sbjct: 621 VSQVNPRDAKACVVHGSDLKD----MTSEQLDDILKYHTEI---------VFARTSPQQK 667 Query: 855 TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----C 910 +V Q+ V + GDG ND ALK AD+G+++ A S VS + M ++ Sbjct: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDDNFAS 726 Query: 911 VPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLV 964 + + EGR D K Y+LT I + I+ I LG + L IDL Sbjct: 727 IVTGVEEGRLIFDN----LKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLG 782 Query: 965 ITTTVAVLMSRTGPALVLGRVRP----PGALLSVPVLSSLLLQMVLVTGVQLGG---YFL 1017 A+ ++ + + +P L++ ++S Q+ ++ LGG YF+ Sbjct: 783 TDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQA--LGGFFTYFV 840 Query: 1018 TLAQPWFVPLN 1028 LA+ F+P++ Sbjct: 841 ILAENGFLPIH 851 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 123 bits (308), Expect = 1e-27 Identities = 212/911 (23%), Positives = 363/911 (39%), Gaps = 127/911 (13%) Query: 179 QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233 +VS+ DH S D++HR GL+ A GPN ++ P + + L Sbjct: 38 EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 96 Query: 234 PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274 F FS+ LW+ + A I ++S++ I C S Y+ Sbjct: 97 ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 152 Query: 275 KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333 K S+ + + + + GE+ +++ E+V GD LV + G +P D ++ A C Sbjct: 153 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 211 Query: 334 MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393 V+ SSLTGES P +T P+ ET R+ F T ++ A +V T Sbjct: 212 KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 261 Query: 394 GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449 G T G + ++S L PI + +H + + ++V LG + I L L Sbjct: 262 GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 318 Query: 450 NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509 E VI + ++ VP L A +TVC R+ R+ + + G +C DK Sbjct: 319 -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 377 Query: 510 TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569 TGTLT++ M V + + + AT ALSR+ + + Sbjct: 378 TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 432 Query: 570 LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629 + + +L+ A D++ + + E +++E + + PF+S Sbjct: 433 FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 486 Query: 630 QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676 + + P ++P+ +KG+PE + C+ E + F Sbjct: 487 KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 546 Query: 677 AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734 G RV+ LP E Q T D +L +GL+ M + + + Sbjct: 547 GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 606 Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794 R I+ +MVTGD+ TA +A+G G+++ ++E + Sbjct: 607 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE---------------TVEDIAARLNIP 651 Query: 795 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854 V+ V D A D + ++ I+K+ ++ VFAR +P+QK Sbjct: 652 VSQVNPRDAKACVVHGSDLKD----MTSEQLDDILKYHTEI---------VFARTSPQQK 698 Query: 855 TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----C 910 +V Q+ V + GDG ND ALK AD+G+++ A S VS + M ++ Sbjct: 699 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDDNFAS 757 Query: 911 VPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLV 964 + + EGR D K Y+LT I + I+ I LG + L IDL Sbjct: 758 IVTGVEEGRLIFDN----LKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLG 813 Query: 965 ITTTVAVLMSRTGPALVLGRVRP----PGALLSVPVLSSLLLQMVLVTGVQLGG---YFL 1017 A+ ++ + + +P L++ ++S Q+ ++ LGG YF+ Sbjct: 814 TDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQA--LGGFFTYFV 871 Query: 1018 TLAQPWFVPLN 1028 LA+ F+P++ Sbjct: 872 ILAENGFLPIH 882 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 112 bits (279), Expect = 3e-24 Identities = 184/793 (23%), Positives = 311/793 (39%), Gaps = 99/793 (12%) Query: 212 GPNVISIP------VKSYPQLLVDEALNPYYG----FQAFSIALWLADHYYWYALCIFLI 261 GPN ++ P VK QL +L + G F A+SI ++ + L + ++ Sbjct: 84 GPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIV 143 Query: 262 SSISI----CLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQ 317 S+ + C S Y+ K S+ + + + + GGE+ ++ E+V GD LV + Sbjct: 144 LSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGD-LVEIK 202 Query: 318 EGGLMPCDAALVAGE-CMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLIL 376 G +P D L++ + C V+ SSLTGES P ++ P+ ET R+ F T + Sbjct: 203 GGDRVPADLRLISAQGCKVDNSSLTGESEPQSRS--PDFTHENPLET--RNICFFSTNCV 258 Query: 377 QARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLAL-LGT 435 + A +V TG T G + S F+ ++V+A+ LG Sbjct: 259 EGTAR------GIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGV 312 Query: 436 IYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLR 495 + L L E +I + ++ VP L A +TVC R+ R+ + Sbjct: 313 TFFALSLLLGYGWL-EAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEA 371 Query: 496 INLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHA 555 + G +C DKTGTLT++ M V + + ++ T Sbjct: 372 VETLGSTSTICSDKTGTLTQNR---MTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFM 428 Query: 556 LSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPV 615 L+R+ + + D K + + + D++ + + E ++ E Sbjct: 429 LARI--AGLCNRADFKANQEILPIAKRATTGDASESALLKFI------EQSYSSVAEMRE 480 Query: 616 PVSVLHRFPFSSALQ-RMSVVVAWPGATQPEAYVKGSPELVAGLCNP-----------ET 663 + PF+S + +MS+ + + +KG+PE + C+ + Sbjct: 481 KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE 540 Query: 664 VPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVE---GDLSLLGLLVMR 720 + F G RV+ LP+ S D + +L +GL+ M Sbjct: 541 MKEAFQNAYLELGGLGERVLGFCFLNLPS--SFSKGFPFNTDEINFPMDNLCFVGLISMI 598 Query: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780 + + + R I+ +MVTGD+ TA +A+G G II T Sbjct: 599 DPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVG--------IISEGTETAEEV 650 Query: 781 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840 A L+ +P+ A AA V + + I+++ P++ Sbjct: 651 AARLK-IPISKVDA--------SAAKAIVVHGAELKD--IQSKQLDQILQNHPEI----- 694 Query: 841 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900 VFAR +P+QK +V Q+L V + GDG ND ALK AD+GI++ S VS Sbjct: 695 ----VFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMG-ISGSDVSK 749 Query: 901 FTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTIN 950 + M ++ + + EGR D K +Y+LT I + I+ I Sbjct: 750 QAADMILLDDNFASIVTGVEEGRLIFDN----LKKSIMYTLTSNIPEITPFLMFIILGIP 805 Query: 951 TNLGDLQFLAIDL 963 LG + L IDL Sbjct: 806 LPLGTITILCIDL 818 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 105 bits (263), Expect = 2e-22 Identities = 196/871 (22%), Positives = 350/871 (40%), Gaps = 122/871 (14%) Query: 212 GPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLS-- 269 GPN ++ P K P+++ + L G FSI LW+ W A I S S L+ Sbjct: 91 GPNSLT-PPKQTPEIV--KFLKQMVG--GFSILLWVGAFLCWIAYGIQYSSDKSASLNNV 145 Query: 270 -----------------LYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDC 312 Y+ K + + K+ + + E++ + S +LV GD Sbjct: 146 YLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGD- 204 Query: 313 LVLPQEGGLMPCDAALVAGE-CMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFC 371 +V + G +P D +++ + C V+ SSLTGES P P +E + L Sbjct: 205 IVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQ----------PRSSEFTHENPLET 254 Query: 372 GTLILQARAYVGPHVLAVVTRTGFCTAKG---GLVSSILHPR-PINFKFYKHSMKFVAAL 427 + + + V +V TG T G L S + + + PI + +H + VA + Sbjct: 255 KNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEI-EHFVHIVAGV 313 Query: 428 SV-LALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQ 486 +V + +L I ++ + Y+ + + +I + ++ VP L A +TV R+ ++ Sbjct: 314 AVSIGILFFIIAVSLKYQ----VLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKK 369 Query: 487 GIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPL 546 + + G ++C DKTGTLT++ + V + Q F+ E V Sbjct: 370 NCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLW-FDNQIFVADTSEDHSNQV--F 426 Query: 547 LRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL---AVMRPPLW 603 ++ T +LS++ + + + K + ++++ D A T +L V+ + Sbjct: 427 DQSSRTWASLSKI--ITLCNRAEFKPGQENVPIMKKAVIGD-ASETALLKFSEVILGDVM 483 Query: 604 EPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLC---- 659 E + + + +P + ++F S + M P + +KG+PE + C Sbjct: 484 EIRKRNRKVAEIPFNSTNKFQLS--IHEMDD----PHGKRFLMVMKGAPERILEKCSTIM 537 Query: 660 -NPETVPTDFAQMLQSYTA------AGYRVVALASKPLPT--VPSLEAAQQLTRDTVEGD 710 N E P D + +TA G RV+ LP P + + + Sbjct: 538 INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSN 597 Query: 711 LSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLII 770 L +GLL M + + + R I+ +MVTGD+ TA +A+ G+++ Sbjct: 598 LCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSE--- 654 Query: 771 VHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVK 830 ++E + AV V D A+ + + +S I+ Sbjct: 655 ------------TVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKD----MSSEQLDEILA 698 Query: 831 HFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISL 890 ++ Q VFAR +P+QK +V Q+ V + GDG ND ALK AD+GI++ Sbjct: 699 NY---------QEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAM 749 Query: 891 SQAEASVVSPFTSSMA---SIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFIS----- 942 A + + + + + EGR D K YSLT+ I+ Sbjct: 750 GIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDN----LKKTIAYSLTKNIAELCPF 805 Query: 943 -VLILYTINTNLGDLQFLAIDL--VITTTVAVLMSRTGPALVLGRVRPPG--ALLSVP-- 995 + I+ + +G + L IDL I ++A+ + ++ + R L++ P Sbjct: 806 LIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLA 865 Query: 996 VLSSLLLQMVLVTGVQLGGYFLTLAQPWFVP 1026 V S L + ++ G L YF AQ F+P Sbjct: 866 VYSYLHIGLMQALGAFL-VYFTVYAQEGFLP 895 >gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens] Length = 1243 Score = 96.7 bits (239), Expect = 1e-19 Identities = 151/733 (20%), Positives = 281/733 (38%), Gaps = 91/733 (12%) Query: 296 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 355 G EEE D + GD L LP G +AA A +VN G ++ ++ + Sbjct: 293 GEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDG-NVDASQSKAKQQ 351 Query: 356 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVV----TRTGFCTAKGGLVSSILHPRP 411 G E + G + +A + +V+ T+ K GLV S + Sbjct: 352 DGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAI--TV 409 Query: 412 INFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAA 471 I Y FV ++ L +++ Y + I + ++ V VP LP A Sbjct: 410 IILVLYFTVDTFV--VNKKPWLPECTPVYVQY-----FVKFFIIGVTVLVVAVPEGLPLA 462 Query: 472 MTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAF 531 +T+ Y+ ++ + H G +C DKTGTLT + + V V G Sbjct: 463 VTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV--VQAYVGDVH 520 Query: 532 LPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFG 591 +P+P + + L A++ T + P E G L + + G Sbjct: 521 YKEIPDPSSINT-KTMELLINAIAINSAYTTKILPP------EKEG-ALPRQVGNKTECG 572 Query: 592 TQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGS 651 + +EP M E + + F+S + MS V+ P + Y KG+ Sbjct: 573 LLGFVLDLKQDYEPVRSQMPEE----KLYKVYTFNSVRKSMSTVIKLPDESF-RMYSKGA 627 Query: 652 PELVAGLC-------------NPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEA 698 E+V C P ++++ G R + +A + P+ P + Sbjct: 628 SEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW 687 Query: 699 AQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARG 758 + + + +L+ + ++ + + ++P+ I+ +R I MVTGDN+ TA +A Sbjct: 688 DNE---NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIK 744 Query: 759 CGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHL 818 CG++ P E + + R + E + P+ R L Sbjct: 745 CGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI----------------WPKLRVL 788 Query: 819 ALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 878 A S PT KH LV+G + + +++ V + GDG ND Sbjct: 789 ARSSPT----DKH-------TLVKGIIDSTHTEQRQV------------VAVTGDGTNDG 825 Query: 879 GALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLT 938 ALK ADVG ++ A V + + + + +++ + S+ K++ Sbjct: 826 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 885 Query: 939 QFISVLILY-----TINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLS 993 ++V++ + T ++ L +Q L ++L++ T ++ ++ P L +P G + Sbjct: 886 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGR--N 943 Query: 994 VPVLSSLLLQMVL 1006 P++S +++ +L Sbjct: 944 KPLISRTMMKNIL 956 Score = 38.5 bits (88), Expect = 0.038 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 7/96 (7%) Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315 +C+ L+++ + + KQ + L+ ++ + V R G+ + +E+V GD + Sbjct: 162 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVVR-AGQVVQIPVAEIVVGD-IAQ 215 Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350 + G L+P D + G + ++ESSLTGES V K+ Sbjct: 216 VKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS 251 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 96.7 bits (239), Expect = 1e-19 Identities = 220/998 (22%), Positives = 380/998 (38%), Gaps = 167/998 (16%) Query: 189 CDDVHRSRHGLSLQDQMVRKAIYGPNVI----SIPV-KSYPQLLVDEALNPYYGFQAFSI 243 C D+H GLS R+ +G N S PV K Y +D+ NP S Sbjct: 70 CVDLHT---GLSEFSVTQRRLAHGWNEFVADNSEPVWKKY----LDQFKNPLILLLLGSA 122 Query: 244 ALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVD 303 + + Y A+ I + + ++ + + ++L ++ K+ C C G+ + + Sbjct: 123 LVSVLTKEYEDAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPECNCLREGKLQHLL 182 Query: 304 SSELVPGDCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALP-EGLGPYCA 361 + ELVPGD + L G +P D L + +V+ESS TGE+ P KT P G G Sbjct: 183 ARELVPGDVVSL-SIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDL-- 239 Query: 362 ETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSM 421 T + +F GTL+ R VV TG +++ G V ++ + SM Sbjct: 240 -TTLSNIVFMGTLVQYGRGQ------GVVIGTGE-SSQFGEVFKMMQAEETPKTPLQKSM 291 Query: 422 KFVAALSVLALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480 + L G I I ++ + L + + L +P LP + V + Sbjct: 292 DRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGV 351 Query: 481 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKG-QAFLPLVPEPR 539 R+ ++ + + G ++C DKTGTLT + + V +V G +A + V Sbjct: 352 LRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDG 411 Query: 540 RLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMR 599 + V L + + + VG ++ V + + + G + M+ Sbjct: 412 QGTVC----LLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMK 467 Query: 600 PPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAY-VKGSPELVAGL 658 L + + + + +P FSS + M+V + Q + Y +KG+ E V Sbjct: 468 MDLSDIKNSYIRKKEIP--------FSSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRY 519 Query: 659 C---NPETVPTDFAQMLQSYT--------AAGYRVVALASKPLPTVPSLEAAQQLTRDTV 707 C N +P +S+ + G RV+ALAS P Sbjct: 520 CTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGP-----------------E 562 Query: 708 EGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEH 767 G L+ LGL+ + + + +Q L + + M+TGD L+TA+ + R G+ Sbjct: 563 LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLC----- 617 Query: 768 LIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGI 827 L+ + E +V + D+ +V F Sbjct: 618 -------------NGKLQAMSGEEVDSVEKGELADRVGKVSV--------------FFRT 650 Query: 828 IVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVG 887 KH K++ + G + V M GDG ND ALK+AD+G Sbjct: 651 SPKHKLKIIKALQESGAI----------------------VAMTGDGVNDAVALKSADIG 688 Query: 888 ISLSQAEASVVSPFTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLTQFISV 943 I++ Q + VS ++M ++ + + EG+ F K + L+ IS Sbjct: 689 IAMGQT-GTDVSKEAANMILVDDDFSAIMNAVEEGK----GIFYNIKNFVRFQLSTSISA 743 Query: 944 LILYTINT------NLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVL 997 L L T++T L +Q L I++++ A + P +PP ++ + Sbjct: 744 LSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLG-VEPVDKDAFRQPPRSVRDTILS 802 Query: 998 SSLLLQMVLVTGVQLGGYFLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILA 1057 +L+L++++ + + G TL W P++ + T + + F + L Sbjct: 803 RALILKILMSAAIIISG---TLFIFW-------KEMPEDRASTPRTTTMTFTCFVFFDLF 852 Query: 1058 AAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVLVPGLLQGPLALRNI--TDTGFKLLL 1115 A++ + L + FL L SVL G + G LA+ I F+ Sbjct: 853 NALT--CRSQTKLIFEIGFLRNHMFLYSVL-------GSILGQLAVIYIPPLQRVFQTEN 903 Query: 1116 LGLVTLNFV-----GAFMLESVLDQCLPACLRRLRPKR 1148 LG + L F+ F+L +L C C PKR Sbjct: 904 LGALDLLFLTGLASSVFILSELLKLCEKYC---CSPKR 938 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 94.7 bits (234), Expect = 4e-19 Identities = 117/571 (20%), Positives = 225/571 (39%), Gaps = 77/571 (13%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 400 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 459 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V V G +P+P + + L A++ T + P Sbjct: 460 TTNRMTV--VQAYVGDVHYKEIPDPSSINT-KTMELLINAIAINSAYTTKILPP------ 510 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMS 633 E G L + + G + +EP M E + + F+S + MS Sbjct: 511 EKEG-ALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEE----KLYKVYTFNSVRKSMS 565 Query: 634 VVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAAGY 680 V+ P + Y KG+ E+V C P ++++ G Sbjct: 566 TVIKLPDESF-RMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGL 624 Query: 681 RVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIR 740 R + +A + P+ P + + + + +L+ + ++ + + ++P+ I+ +R I Sbjct: 625 RTICVAYRDFPSSPEPDWDNE---NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGIT 681 Query: 741 AVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKD 800 MVTGDN+ TA +A CG++ P E + + R + E + Sbjct: 682 VRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI----- 736 Query: 801 PDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCE 860 P+ R LA S PT KH LV+G + + +++ Sbjct: 737 -----------WPKLRVLARSSPT----DKH-------TLVKGIIDSTHTEQRQV----- 769 Query: 861 LQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRC 920 V + GDG ND ALK ADVG ++ A V + + + + +++ Sbjct: 770 -------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMW 822 Query: 921 SLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAVLMSR 975 + S+ K++ ++V++ + T ++ L +Q L ++L++ T ++ ++ Sbjct: 823 GRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALAT 882 Query: 976 TGPALVLGRVRPPGALLSVPVLSSLLLQMVL 1006 P L +P G + P++S +++ +L Sbjct: 883 EPPTETLLLRKPYGR--NKPLISRTMMKNIL 911 Score = 38.5 bits (88), Expect = 0.038 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 7/96 (7%) Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315 +C+ L+++ + + KQ + L+ ++ + V R G+ + +E+V GD + Sbjct: 162 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVVR-AGQVVQIPVAEIVVGD-IAQ 215 Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350 + G L+P D + G + ++ESSLTGES V K+ Sbjct: 216 VKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS 251 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 93.2 bits (230), Expect = 1e-18 Identities = 133/621 (21%), Positives = 246/621 (39%), Gaps = 92/621 (14%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 419 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 478 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V V G +P P L +L L +++ T + P Sbjct: 479 TTNRMTV--VQSYLGDTHYKEIPAPSAL-TPKILDLLVHAISINSAYTTKILPP------ 529 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQ--LQAMEEPPVPVSVLHR-FPFSSALQ 630 E+E A G + + + + + Q + E +P L++ + F+S + Sbjct: 530 -------EKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ-IPEDKLYKVYTFNSVRK 581 Query: 631 RMSVVVAWPGATQPEAYVKGSPELVAGLCN-------------PETVPTDFAQMLQSYTA 677 MS V+ P + KG+ E++ C P ++++ Sbjct: 582 SMSTVIRMPDGGF-RLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMAC 640 Query: 678 AGYRVVALASKPLPTVPSLEAAQQLTRDT---VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734 G R + +A + A Q+ D V GDL+ + ++ + + ++P+ I+ Sbjct: 641 DGLRTICIAYR------DFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKC 694 Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794 +R I MVTGDN+ TA +A CG++ P E + + R + E Sbjct: 695 QRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDK 754 Query: 795 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854 V P+ R LA S PT KH LV+G + + +++ Sbjct: 755 V----------------WPKLRVLARSSPT----DKH-------TLVKGIIDSTTGEQRQ 787 Query: 855 TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMV 914 V + GDG ND ALK ADVG ++ A V + + + + + Sbjct: 788 V------------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSI 835 Query: 915 IREGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTV 969 ++ + S+ K++ ++V++ + T ++ L +Q L ++L++ T Sbjct: 836 VKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFA 895 Query: 970 AVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGV-QLGGYF-LTLAQPWFVPL 1027 ++ ++ P L +P G P++S +++ +L V QL F L F + Sbjct: 896 SLALATEPPTESLLLRKPYGR--DKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDI 953 Query: 1028 NRTVAAPDNLPNYEN-TVVFS 1047 + AP + P E+ T++F+ Sbjct: 954 DSGRNAPLHSPPSEHYTIIFN 974 Score = 39.3 bits (90), Expect = 0.022 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%) Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315 +C+ L+++ + + KQ + L+ ++ + V R G+ V + LV GD + Sbjct: 165 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-NGQLLQVPVAALVVGD-IAQ 218 Query: 316 PQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTA 351 + G L+P D L+ A + ++ESSLTGES V K+A Sbjct: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSA 255 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 93.2 bits (230), Expect = 1e-18 Identities = 133/621 (21%), Positives = 246/621 (39%), Gaps = 92/621 (14%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 419 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 478 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V V G +P P L +L L +++ T + P Sbjct: 479 TTNRMTV--VQSYLGDTHYKEIPAPSAL-TPKILDLLVHAISINSAYTTKILPP------ 529 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQ--LQAMEEPPVPVSVLHR-FPFSSALQ 630 E+E A G + + + + + Q + E +P L++ + F+S + Sbjct: 530 -------EKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ-IPEDKLYKVYTFNSVRK 581 Query: 631 RMSVVVAWPGATQPEAYVKGSPELVAGLCN-------------PETVPTDFAQMLQSYTA 677 MS V+ P + KG+ E++ C P ++++ Sbjct: 582 SMSTVIRMPDGGF-RLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMAC 640 Query: 678 AGYRVVALASKPLPTVPSLEAAQQLTRDT---VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734 G R + +A + A Q+ D V GDL+ + ++ + + ++P+ I+ Sbjct: 641 DGLRTICIAYR------DFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKC 694 Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794 +R I MVTGDN+ TA +A CG++ P E + + R + E Sbjct: 695 QRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDK 754 Query: 795 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQK 854 V P+ R LA S PT KH LV+G + + +++ Sbjct: 755 V----------------WPKLRVLARSSPT----DKH-------TLVKGIIDSTTGEQRQ 787 Query: 855 TELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMV 914 V + GDG ND ALK ADVG ++ A V + + + + + Sbjct: 788 V------------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSI 835 Query: 915 IREGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTV 969 ++ + S+ K++ ++V++ + T ++ L +Q L ++L++ T Sbjct: 836 VKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFA 895 Query: 970 AVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGV-QLGGYF-LTLAQPWFVPL 1027 ++ ++ P L +P G P++S +++ +L V QL F L F + Sbjct: 896 SLALATEPPTESLLLRKPYGR--DKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDI 953 Query: 1028 NRTVAAPDNLPNYEN-TVVFS 1047 + AP + P E+ T++F+ Sbjct: 954 DSGRNAPLHSPPSEHYTIIFN 974 Score = 39.3 bits (90), Expect = 0.022 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%) Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315 +C+ L+++ + + KQ + L+ ++ + V R G+ V + LV GD + Sbjct: 165 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-NGQLLQVPVAALVVGD-IAQ 218 Query: 316 PQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTA 351 + G L+P D L+ A + ++ESSLTGES V K+A Sbjct: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSA 255 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 92.0 bits (227), Expect = 3e-18 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%) Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250 ++GL+ + R+A +G N I K Y + + NP S + + H Sbjct: 43 QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98 Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310 + A+ I + I + ++ + + ++L ++ KL C C G+ E + +LVPG Sbjct: 99 QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158 Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369 D + L G +P D L A + ++ESSLTGE+ P K P+ R + Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217 Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429 F GTL+ +A VV TG ++ G V ++ + SM + Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270 Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487 G I I ++ + + E+ ++ L +P LP +TV R+ +++ Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330 Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547 I P+ + G ++C DKTGTLT++ + V + G L E + Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384 Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607 + + + V ++ V + + G + M+ L Q Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444 Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661 + + +PFSS + M+V V +PE ++KG+ E V C Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496 Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714 +T+ + Q +AG RV+ALAS P G L+ L Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539 Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771 GL+ ++ P T V +A L + + M+TGD+ +TAV +A G+ Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586 Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831 + + Q S E + ++ + P A Y P RH Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624 Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891 K +++ LQK V M GDG ND ALKAAD+G+++ Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662 Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946 Q V + + + I EG+ + +F F+ + IS+ L Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722 Query: 947 YTINTNLGDLQFLAIDLVI 965 L +Q L I++++ Sbjct: 723 MNFPNPLNAMQILWINIIM 741 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 92.0 bits (227), Expect = 3e-18 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%) Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250 ++GL+ + R+A +G N I K Y + + NP S + + H Sbjct: 43 QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98 Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310 + A+ I + I + ++ + + ++L ++ KL C C G+ E + +LVPG Sbjct: 99 QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158 Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369 D + L G +P D L A + ++ESSLTGE+ P K P+ R + Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217 Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429 F GTL+ +A VV TG ++ G V ++ + SM + Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270 Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487 G I I ++ + + E+ ++ L +P LP +TV R+ +++ Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330 Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547 I P+ + G ++C DKTGTLT++ + V + G L E + Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384 Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607 + + + V ++ V + + G + M+ L Q Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444 Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661 + + +PFSS + M+V V +PE ++KG+ E V C Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496 Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714 +T+ + Q +AG RV+ALAS P G L+ L Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539 Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771 GL+ ++ P T V +A L + + M+TGD+ +TAV +A G+ Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586 Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831 + + Q S E + ++ + P A Y P RH Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624 Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891 K +++ LQK V M GDG ND ALKAAD+G+++ Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662 Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946 Q V + + + I EG+ + +F F+ + IS+ L Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722 Query: 947 YTINTNLGDLQFLAIDLVI 965 L +Q L I++++ Sbjct: 723 MNFPNPLNAMQILWINIIM 741 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 92.0 bits (227), Expect = 3e-18 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%) Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250 ++GL+ + R+A +G N I K Y + + NP S + + H Sbjct: 43 QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98 Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310 + A+ I + I + ++ + + ++L ++ KL C C G+ E + +LVPG Sbjct: 99 QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158 Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369 D + L G +P D L A + ++ESSLTGE+ P K P+ R + Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217 Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429 F GTL+ +A VV TG ++ G V ++ + SM + Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270 Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487 G I I ++ + + E+ ++ L +P LP +TV R+ +++ Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330 Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547 I P+ + G ++C DKTGTLT++ + V + G L E + Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384 Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607 + + + V ++ V + + G + M+ L Q Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444 Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661 + + +PFSS + M+V V +PE ++KG+ E V C Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496 Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714 +T+ + Q +AG RV+ALAS P G L+ L Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539 Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771 GL+ ++ P T V +A L + + M+TGD+ +TAV +A G+ Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586 Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831 + + Q S E + ++ + P A Y P RH Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624 Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891 K +++ LQK V M GDG ND ALKAAD+G+++ Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662 Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946 Q V + + + I EG+ + +F F+ + IS+ L Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722 Query: 947 YTINTNLGDLQFLAIDLVI 965 L +Q L I++++ Sbjct: 723 MNFPNPLNAMQILWINIIM 741 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 92.0 bits (227), Expect = 3e-18 Identities = 175/799 (21%), Positives = 300/799 (37%), Gaps = 129/799 (16%) Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250 ++GL+ + R+A +G N I K Y + + NP S + + H Sbjct: 43 QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98 Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310 + A+ I + I + ++ + + ++L ++ KL C C G+ E + +LVPG Sbjct: 99 QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158 Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369 D + L G +P D L A + ++ESSLTGE+ P K P+ R + Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217 Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429 F GTL+ +A VV TG ++ G V ++ + SM + Sbjct: 218 FMGTLVRCGKA------KGVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270 Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487 G I I ++ + + E+ ++ L +P LP +TV R+ +++ Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330 Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547 I P+ + G ++C DKTGTLT++ + V + G L E + Sbjct: 331 IVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384 Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607 + + + V ++ V + + G + M+ L Q Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444 Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNP---- 661 + + +PFSS + M+V V +PE ++KG+ E V C Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496 Query: 662 -ETVPTD------FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714 +T+ + Q +AG RV+ALAS P G L+ L Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539 Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771 GL+ ++ P T V +A L + + M+TGD+ +TAV +A G+ Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586 Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKH 831 + + Q S E + ++ + P A Y P RH Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLSQIV-PKVAVFYRASP----RH-------------- 624 Query: 832 FPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLS 891 K +++ LQK V M GDG ND ALKAAD+G+++ Sbjct: 625 ----------------------KMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMG 662 Query: 892 QAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--SFSVFKYMALYSLTQFISVLIL 946 Q V + + + I EG+ + +F F+ + IS+ L Sbjct: 663 QTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722 Query: 947 YTINTNLGDLQFLAIDLVI 965 L +Q L I++++ Sbjct: 723 MNFPNPLNAMQILWINIIM 741 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 91.3 bits (225), Expect = 5e-18 Identities = 132/619 (21%), Positives = 252/619 (40%), Gaps = 87/619 (14%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 421 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V V + VPEP +P +L L T +++ + + P Sbjct: 481 TMNRMTV--VQAYINEKHYKKVPEPEAIPPN-ILSYLVTGISVNCAYTSKILPP------ 531 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAME-EPPVPVSVLHR-FPFSSALQR 631 E+E G + + L + + + +P L++ + F+S + Sbjct: 532 -------EKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKS 584 Query: 632 MSVVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAA 678 MS V+ + + KG+ E++ C P +++ + Sbjct: 585 MSTVLKNSDGSY-RIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643 Query: 679 GYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTR 738 G R + LA + P E D V G L+ + ++ + + ++P+ I+ +R Sbjct: 644 GLRTICLAFRDFPAGEP-EPEWDNENDIVTG-LTCIAVVGIEDPVRPEVPDAIKKCQRAG 701 Query: 739 IRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGV 798 I MVTGDN+ TA +A CG++ P E +FL +E + Sbjct: 702 ITVRMVTGDNINTARAIATKCGILHPGE------------------DFLCLEGKDFNRRI 743 Query: 799 K-DPDQAASYTVEPD-PRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856 + + + ++ P+ R LA S PT KH LV+G + + ++ +++ Sbjct: 744 RNEKGEIEQERIDKIWPKLRVLARSSPTD----KH-------TLVKGIIDSTVSDQRQV- 791 Query: 857 LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916 V + GDG ND ALK ADVG ++ A V + + + + +++ Sbjct: 792 -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840 Query: 917 EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971 + S+ K++ ++V++ + T ++ L +Q L ++L++ T ++ Sbjct: 841 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900 Query: 972 LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTG-VQLGGYF-LTLAQPWFVPLNR 1029 ++ P L +P G + P++S +++ +L QL F L A F ++ Sbjct: 901 ALATEPPTESLLLRKPYGR--NKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDS 958 Query: 1030 TVAAPDNLPNYEN-TVVFS 1047 AP + P E+ T+VF+ Sbjct: 959 GRNAPLHAPPSEHYTIVFN 977 Score = 38.5 bits (88), Expect = 0.038 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 7/96 (7%) Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315 +C+ L+++ + + KQ + L+ ++ + V R GG+ + +++ GD + Sbjct: 164 VCVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-GGQVIQIPVADITVGD-IAQ 217 Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350 + G L+P D L+ G + ++ESSLTGES V K+ Sbjct: 218 VKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS 253 >gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sapiens] Length = 1220 Score = 91.3 bits (225), Expect = 5e-18 Identities = 132/619 (21%), Positives = 252/619 (40%), Gaps = 87/619 (14%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 421 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V V + VPEP +P +L L T +++ + + P Sbjct: 481 TMNRMTV--VQAYINEKHYKKVPEPEAIPPN-ILSYLVTGISVNCAYTSKILPP------ 531 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAME-EPPVPVSVLHR-FPFSSALQR 631 E+E G + + L + + + +P L++ + F+S + Sbjct: 532 -------EKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKS 584 Query: 632 MSVVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAA 678 MS V+ + + KG+ E++ C P +++ + Sbjct: 585 MSTVLKNSDGSY-RIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643 Query: 679 GYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTR 738 G R + LA + P E D V G L+ + ++ + + ++P+ I+ +R Sbjct: 644 GLRTICLAFRDFPAGEP-EPEWDNENDIVTG-LTCIAVVGIEDPVRPEVPDAIKKCQRAG 701 Query: 739 IRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGV 798 I MVTGDN+ TA +A CG++ P E +FL +E + Sbjct: 702 ITVRMVTGDNINTARAIATKCGILHPGE------------------DFLCLEGKDFNRRI 743 Query: 799 K-DPDQAASYTVEPD-PRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856 + + + ++ P+ R LA S PT KH LV+G + + ++ +++ Sbjct: 744 RNEKGEIEQERIDKIWPKLRVLARSSPTD----KH-------TLVKGIIDSTVSDQRQV- 791 Query: 857 LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916 V + GDG ND ALK ADVG ++ A V + + + + +++ Sbjct: 792 -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840 Query: 917 EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971 + S+ K++ ++V++ + T ++ L +Q L ++L++ T ++ Sbjct: 841 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900 Query: 972 LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTG-VQLGGYF-LTLAQPWFVPLNR 1029 ++ P L +P G + P++S +++ +L QL F L A F ++ Sbjct: 901 ALATEPPTESLLLRKPYGR--NKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDS 958 Query: 1030 TVAAPDNLPNYEN-TVVFS 1047 AP + P E+ T+VF+ Sbjct: 959 GRNAPLHAPPSEHYTIVFN 977 Score = 38.5 bits (88), Expect = 0.038 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 7/96 (7%) Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315 +C+ L+++ + + KQ + L+ ++ + V R GG+ + +++ GD + Sbjct: 164 VCVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-GGQVIQIPVADITVGD-IAQ 217 Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350 + G L+P D L+ G + ++ESSLTGES V K+ Sbjct: 218 VKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS 253 >gi|222352161 ATPase, class V, type 10D [Homo sapiens] Length = 1426 Score = 87.0 bits (214), Expect = 9e-17 Identities = 87/323 (26%), Positives = 139/323 (43%), Gaps = 48/323 (14%) Query: 614 PVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGL---CNPETVPTDFAQ 670 P+ +LH PF S +RMSVVV P + Q Y KG+ ++ L +P+ + Q Sbjct: 761 PLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQ 820 Query: 671 M---------LQSYTAAGYRVVALASKPLPTVP-------------SLEAAQQLTRDT-- 706 M L Y G R + +A K + S++ ++L ++ Sbjct: 821 MIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAM 880 Query: 707 -VEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQ 765 +E L+LLG + + L+ I+AL + I+ M+TGD +TAV +A C ++ P Sbjct: 881 RLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPD 940 Query: 766 EHLIIVHATHPER-GQPASLEFLPMESPTAVNGVKDPDQAA---SYTVEPDPRS----RH 817 + L I++ + G S ++ T P+Q + P PR Sbjct: 941 DKLFILNTQSKDACGMLMSTILKELQKKTQAL----PEQVSLSEDLLQPPVPRDSGLRAG 996 Query: 818 LALSGPTFGI-----IVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQK-LQYCVGMC 871 L ++G T + K F +L Q V R P QK+E+V ++ LQ Sbjct: 997 LIITGKTLEFALQESLQKQFLELTS--WCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAI 1054 Query: 872 GDGANDCGALKAADVGISLSQAE 894 GDGAND ++ AD+GI +S E Sbjct: 1055 GDGANDVSMIQVADIGIGVSGQE 1077 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 85.1 bits (209), Expect = 4e-16 Identities = 121/575 (21%), Positives = 234/575 (40%), Gaps = 86/575 (14%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 411 IIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 470 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V+ QA++ + R++P + L ++ D V Sbjct: 471 TMNRMTVV-------QAYIGGI-HYRQIPSPDVF--------LPKVLDLIVNGISINSAY 514 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWE--PQLQAMEEPPVPVSVLHR-FPFSSALQ 630 S E+E G + + + + QA+ VP L++ + F+S + Sbjct: 515 TSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE-VPEEKLYKVYTFNSVRK 573 Query: 631 RMSVVVAWPGATQPEAYVKGSPELVAGLCNP------ETVP------TDFAQ-MLQSYTA 677 MS V+ P Y KG+ E++ CN E VP D + +++ Sbjct: 574 SMSTVIRNPNGGF-RMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632 Query: 678 AGYRVVALASKPLP-TVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRR 736 G R + +A + T PS + ++ + L+ + ++ + + ++P+ I ++ Sbjct: 633 DGLRTICIAYRDFDDTEPSWDNENEILTE-----LTCIAVVGIEDPVRPEVPDAIAKCKQ 687 Query: 737 TRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVN 796 I MVTGDN+ TA +A CG++ P + + + R N Sbjct: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNR--------------LIRN 733 Query: 797 GVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856 + +Q + P + R LA S PT KH LV+G + + + ++ Sbjct: 734 EKGEVEQEKLDKIWP--KLRVLARSSPTD----KH-------TLVKGIIDSTVGEHRQV- 779 Query: 857 LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916 V + GDG ND ALK ADVG ++ A V + + + + +++ Sbjct: 780 -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 828 Query: 917 EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971 + S+ K++ ++V++ + T ++ L +Q L ++L++ T ++ Sbjct: 829 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL 888 Query: 972 LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVL 1006 ++ P L + RP G + P++S +++ +L Sbjct: 889 ALATEPPTESLLKRRPYGR--NKPLISRTMMKNIL 921 Score = 34.7 bits (78), Expect = 0.55 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Query: 271 YKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330 + KQ + L+ ++ + + R G+ + +E+V GD + + G L+P D L+ Sbjct: 171 WSKEKQFRGLQCRIEQEQKFSIIR-NGQLIQLPVAEIVVGD-IAQVKYGDLLPADGILIQ 228 Query: 331 G-ECMVNESSLTGESIPVLKT 350 G + ++ESSLTGES V K+ Sbjct: 229 GNDLKIDESSLTGESDHVKKS 249 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 85.1 bits (209), Expect = 4e-16 Identities = 121/575 (21%), Positives = 234/575 (40%), Gaps = 86/575 (14%) Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513 I + ++ V VP LP A+T+ Y+ ++ + H G +C DKTGTL Sbjct: 411 IIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 470 Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573 T + + V+ QA++ + R++P + L ++ D V Sbjct: 471 TMNRMTVV-------QAYIGGI-HYRQIPSPDVF--------LPKVLDLIVNGISINSAY 514 Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWE--PQLQAMEEPPVPVSVLHR-FPFSSALQ 630 S E+E G + + + + QA+ VP L++ + F+S + Sbjct: 515 TSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE-VPEEKLYKVYTFNSVRK 573 Query: 631 RMSVVVAWPGATQPEAYVKGSPELVAGLCNP------ETVP------TDFAQ-MLQSYTA 677 MS V+ P Y KG+ E++ CN E VP D + +++ Sbjct: 574 SMSTVIRNPNGGF-RMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632 Query: 678 AGYRVVALASKPLP-TVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRR 736 G R + +A + T PS + ++ + L+ + ++ + + ++P+ I ++ Sbjct: 633 DGLRTICIAYRDFDDTEPSWDNENEILTE-----LTCIAVVGIEDPVRPEVPDAIAKCKQ 687 Query: 737 TRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVN 796 I MVTGDN+ TA +A CG++ P + + + R N Sbjct: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNR--------------LIRN 733 Query: 797 GVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTE 856 + +Q + P + R LA S PT KH LV+G + + + ++ Sbjct: 734 EKGEVEQEKLDKIWP--KLRVLARSSPTD----KH-------TLVKGIIDSTVGEHRQV- 779 Query: 857 LVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIR 916 V + GDG ND ALK ADVG ++ A V + + + + +++ Sbjct: 780 -----------VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 828 Query: 917 EGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLVITTTVAV 971 + S+ K++ ++V++ + T ++ L +Q L ++L++ T ++ Sbjct: 829 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL 888 Query: 972 LMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVL 1006 ++ P L + RP G + P++S +++ +L Sbjct: 889 ALATEPPTESLLKRRPYGR--NKPLISRTMMKNIL 921 Score = 34.7 bits (78), Expect = 0.55 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Query: 271 YKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330 + KQ + L+ ++ + + R G+ + +E+V GD + + G L+P D L+ Sbjct: 171 WSKEKQFRGLQCRIEQEQKFSIIR-NGQLIQLPVAEIVVGD-IAQVKYGDLLPADGILIQ 228 Query: 331 G-ECMVNESSLTGESIPVLKT 350 G + ++ESSLTGES V K+ Sbjct: 229 GNDLKIDESSLTGESDHVKKS 249 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 79.7 bits (195), Expect = 1e-14 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%) Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356 + + ++VPGD +V G +P D L+ + V++S LTGES+ V K A+P+ Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196 Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412 P +++ LF GT I +A + V TG T G + S + + P P+ Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249 Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463 K + + A+SV+ + + +I R V +I A+ L Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306 Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521 +P LPA +T C R+ R+ + G ++C DKTGTLT + + V M Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366 Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563 VV + G + P +P R L LAT AL Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426 Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621 + + K+ E+T L + F T + A+ R ++ + L Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479 Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665 R F+ R MSV P + +VKG+PE V C+ V P Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539 Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719 T Q+L G R +ALA++ P +E E DL+ +G + M Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599 Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766 + +P+ I + IR VM+TGDN TAV + R G+ E Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%) Query: 846 FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903 FAR+ P K+ +V LQ M GDG ND ALK A++GI++ A A + Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735 Query: 904 SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961 S + + + EGR +Y+ ++ + + + + + + L +Q L + Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795 Query: 962 DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021 +LV A + P L + P ++S L L GV +G + A Sbjct: 796 NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853 Query: 1022 PWFV 1025 WFV Sbjct: 854 WWFV 857 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 79.7 bits (195), Expect = 1e-14 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%) Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356 + + ++VPGD +V G +P D L+ + V++S LTGES+ V K A+P+ Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196 Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412 P +++ LF GT I +A + V TG T G + S + + P P+ Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249 Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463 K + + A+SV+ + + +I R V +I A+ L Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306 Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521 +P LPA +T C R+ R+ + G ++C DKTGTLT + + V M Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366 Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563 VV + G + P +P R L LAT AL Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426 Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621 + + K+ E+T L + F T + A+ R ++ + L Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479 Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665 R F+ R MSV P + +VKG+PE V C+ V P Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539 Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719 T Q+L G R +ALA++ P +E E DL+ +G + M Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599 Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766 + +P+ I + IR VM+TGDN TAV + R G+ E Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%) Query: 846 FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903 FAR+ P K+ +V LQ M GDG ND ALK A++GI++ A A + Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735 Query: 904 SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961 S + + + EGR +Y+ ++ + + + + + + L +Q L + Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795 Query: 962 DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021 +LV A + P L + P ++S L L GV +G + A Sbjct: 796 NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853 Query: 1022 PWFV 1025 WFV Sbjct: 854 WWFV 857 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 79.7 bits (195), Expect = 1e-14 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%) Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356 + + ++VPGD +V G +P D L+ + V++S LTGES+ V K A+P+ Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196 Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412 P +++ LF GT I +A + V TG T G + S + + P P+ Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249 Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463 K + + A+SV+ + + +I R V +I A+ L Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306 Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521 +P LPA +T C R+ R+ + G ++C DKTGTLT + + V M Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366 Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563 VV + G + P +P R L LAT AL Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426 Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621 + + K+ E+T L + F T + A+ R ++ + L Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479 Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665 R F+ R MSV P + +VKG+PE V C+ V P Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539 Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719 T Q+L G R +ALA++ P +E E DL+ +G + M Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599 Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766 + +P+ I + IR VM+TGDN TAV + R G+ E Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%) Query: 846 FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903 FAR+ P K+ +V LQ M GDG ND ALK A++GI++ A A + Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735 Query: 904 SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961 S + + + EGR +Y+ ++ + + + + + + L +Q L + Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795 Query: 962 DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021 +LV A + P L + P ++S L L GV +G + A Sbjct: 796 NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853 Query: 1022 PWFV 1025 WFV Sbjct: 854 WWFV 857 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 79.7 bits (195), Expect = 1e-14 Identities = 132/527 (25%), Positives = 205/527 (38%), Gaps = 82/527 (15%) Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356 + + ++VPGD +V G +P D L+ + V++S LTGES+ V K A+P+ Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196 Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412 P +++ LF GT I +A + V TG T G + S + + P P+ Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249 Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463 K + + A+SV+ + + +I R V +I A+ L Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306 Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521 +P LPA +T C R+ R+ + G ++C DKTGTLT + + V M Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366 Query: 522 GVV-------------PLKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563 VV + G + P +P R L LAT AL Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426 Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621 + + K+ E+T L + F T + A+ R ++ + L Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479 Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665 R F+ R MSV P + +VKG+PE V C+ V P Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539 Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPL-PTVPSLEAAQQLTRDTVEGDLSLLGLLVM 719 T Q+L G R +ALA++ P +E E DL+ +G + M Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599 Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQE 766 + +P+ I + IR VM+TGDN TAV + R G+ E Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTE 646 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%) Query: 846 FARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQ--AEASVVSPFTS 903 FAR+ P K+ +V LQ M GDG ND ALK A++GI++ A A + Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735 Query: 904 SMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI--LYTINTNLGDLQFLAI 961 S + + + EGR +Y+ ++ + + + + + + L +Q L + Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWV 795 Query: 962 DLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQ 1021 +LV A + P L + P ++S L L GV +G + A Sbjct: 796 NLVTDGLPATALGFNPPDLDIMEKLPRSP--REALISGWLFFRYLAIGVYVGLATVAAAT 853 Query: 1022 PWFV 1025 WFV Sbjct: 854 WWFV 857 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,926,801 Number of Sequences: 37866 Number of extensions: 2156170 Number of successful extensions: 5454 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 62 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 5153 Number of HSP's gapped (non-prelim): 197 length of query: 1175 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1062 effective length of database: 13,968,660 effective search space: 14834716920 effective search space used: 14834716920 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.