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Search of human proteins with 21389545
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389545 sterile alpha motif domain containing 8 [Homo
sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389545 sterile alpha motif domain containing 8 [Homo sapiens] 682 0.0
gi|29789379 sphingomyelin synthase 1 [Homo sapiens] 180 2e-45
gi|210147409 sphingomyelin synthase 2 [Homo sapiens] 162 5e-40
gi|210147407 sphingomyelin synthase 2 [Homo sapiens] 162 5e-40
gi|22749271 sphingomyelin synthase 2 [Homo sapiens] 162 5e-40
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ... 40 0.002
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 40 0.002
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 40 0.003
gi|170784854 PTPRF interacting protein, binding protein 2 (lipri... 37 0.024
gi|18079216 CASK interacting protein 1 [Homo sapiens] 34 0.15
gi|7706091 bifunctional apoptosis regulator [Homo sapiens] 31 1.3
gi|38016914 SAM domain- and HD domain-containing protein 1 [Homo... 31 1.7
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 31 1.7
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 31 1.7
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 31 1.7
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 30 2.2
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens] 30 3.8
gi|9256612 protocadherin beta 2 precursor [Homo sapiens] 29 6.5
>gi|21389545 sterile alpha motif domain containing 8 [Homo sapiens]
Length = 326
Score = 682 bits (1761), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIK 60
MAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIK
Sbjct: 1 MAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIK 60
Query: 61 VLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSMTPFISALQSTDWLCNGELSHDCD 120
VLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSMTPFISALQSTDWLCNGELSHDCD
Sbjct: 61 VLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSMTPFISALQSTDWLCNGELSHDCD 120
Query: 121 GPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDM 180
GPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDM
Sbjct: 121 GPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDM 180
Query: 181 QTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVF 240
QTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVF
Sbjct: 181 QTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVF 240
Query: 241 LLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSG 300
LLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSG
Sbjct: 241 LLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSG 300
Query: 301 HTVVLTMLNFFVTECKYLFSASMRIR 326
HTVVLTMLNFFVTECKYLFSASMRIR
Sbjct: 301 HTVVLTMLNFFVTECKYLFSASMRIR 326
>gi|29789379 sphingomyelin synthase 1 [Homo sapiens]
Length = 413
Score = 180 bits (456), Expect = 2e-45
Identities = 108/314 (34%), Positives = 166/314 (52%), Gaps = 33/314 (10%)
Query: 12 WTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLS 71
W+ K VA WL + EY + L G L+ LT+ D + PPL +V D + +L
Sbjct: 7 WSPKKVADWLLENAMPEYCEPL---EHFTGQDLINLTQEDFKKPPL-CRVSSDNGQRLLD 62
Query: 72 VRKLQKI----------HIDVLEEMGYNSDSPMGSMTPFISALQSTDWLCNGELSHDCDG 121
+ + K+ H + +G + +P GS + I + + NG
Sbjct: 63 MIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKIKP----NGMPNGYRKEMIKI 118
Query: 122 PITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQ 181
P+ +L QY E+ KT L+ +Y F T+ ++ +VHERVP +
Sbjct: 119 PMPELERSQYPM--------------EWGKTFLAFLYALSCFVLTTVMISVVHERVPPKE 164
Query: 182 TYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFL 241
PPLPD F D R+ WAF++ E+ GMIL +WL+ LL K++SI+ RR ++GT++L
Sbjct: 165 VQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYL 224
Query: 242 LRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHT-CGDYMFSG 300
RC TM+VT+L VPG H C+ K++G +L R + +G G+++TG H CGDY++SG
Sbjct: 225 YRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNMCGDYLYSG 284
Query: 301 HTVVLTMLNFFVTE 314
HTV+LT+ F+ E
Sbjct: 285 HTVMLTLTYLFIKE 298
>gi|210147409 sphingomyelin synthase 2 [Homo sapiens]
Length = 365
Score = 162 bits (409), Expect = 5e-40
Identities = 74/168 (44%), Positives = 111/168 (66%), Gaps = 1/168 (0%)
Query: 148 EYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVC 207
E+WKT ++ IY T+ ++ +VHERVP + PPLPD F D + R+ WAF+++E+
Sbjct: 75 EWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEIN 134
Query: 208 GMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYG 267
G+IL +W+ L +++SI+ RR C ++GT++L RC TM+VT+L VPG H QC K+ G
Sbjct: 135 GIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNG 194
Query: 268 SVWEKLHRAFAIWSGFGMTLTGVH-TCGDYMFSGHTVVLTMLNFFVTE 314
K+ R + SG G+++TG H CGD++FSGHTV LT+ F+ E
Sbjct: 195 DSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKE 242
>gi|210147407 sphingomyelin synthase 2 [Homo sapiens]
Length = 365
Score = 162 bits (409), Expect = 5e-40
Identities = 74/168 (44%), Positives = 111/168 (66%), Gaps = 1/168 (0%)
Query: 148 EYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVC 207
E+WKT ++ IY T+ ++ +VHERVP + PPLPD F D + R+ WAF+++E+
Sbjct: 75 EWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEIN 134
Query: 208 GMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYG 267
G+IL +W+ L +++SI+ RR C ++GT++L RC TM+VT+L VPG H QC K+ G
Sbjct: 135 GIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNG 194
Query: 268 SVWEKLHRAFAIWSGFGMTLTGVH-TCGDYMFSGHTVVLTMLNFFVTE 314
K+ R + SG G+++TG H CGD++FSGHTV LT+ F+ E
Sbjct: 195 DSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKE 242
>gi|22749271 sphingomyelin synthase 2 [Homo sapiens]
Length = 365
Score = 162 bits (409), Expect = 5e-40
Identities = 74/168 (44%), Positives = 111/168 (66%), Gaps = 1/168 (0%)
Query: 148 EYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVC 207
E+WKT ++ IY T+ ++ +VHERVP + PPLPD F D + R+ WAF+++E+
Sbjct: 75 EWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEIN 134
Query: 208 GMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYG 267
G+IL +W+ L +++SI+ RR C ++GT++L RC TM+VT+L VPG H QC K+ G
Sbjct: 135 GIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNG 194
Query: 268 SVWEKLHRAFAIWSGFGMTLTGVH-TCGDYMFSGHTVVLTMLNFFVTE 314
K+ R + SG G+++TG H CGD++FSGHTV LT+ F+ E
Sbjct: 195 DSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKE 242
>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
sapiens]
Length = 1170
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 9 IRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRL 68
+ W T+ VA WL+ EY DI +H + G LL L DL+ L + +G +KR+
Sbjct: 1098 VHLWGTEEVAAWLEHLSLCEYKDIF-TRHDIRGSELLHLERRDLKD--LGVTKVGHMKRI 1154
Query: 69 MLSVRKLQK 77
+ +++L +
Sbjct: 1155 LCGIKELSR 1163
>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
Length = 1214
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 9 IRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRL 68
+ W T+ VA WL+ EY DI +H + G LL L DL+ L + +G +KR+
Sbjct: 1142 VHLWGTEEVAAWLEHLSLCEYKDIF-TRHDIRGSELLHLERRDLKD--LGVTKVGHMKRI 1198
Query: 69 MLSVRKLQK 77
+ +++L +
Sbjct: 1199 LCGIKELSR 1207
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 9 IRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRL 68
+++W T+ VA WL EY DI +H + G LL L DL+ L I +G +KR+
Sbjct: 1148 VQKWGTEEVAAWLDLLNLGEYKDIFI-RHDIRGAELLHLERRDLKD--LGIPKVGHVKRI 1204
Query: 69 MLSVRKL 75
+ +++L
Sbjct: 1205 LQGIKEL 1211
>gi|170784854 PTPRF interacting protein, binding protein 2 (liprin
beta 2) [Homo sapiens]
Length = 876
Score = 37.0 bits (84), Expect = 0.024
Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 11 RWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLML 70
+W+T+ V WL+D G +YV I + G TLLT T D+ L IK K+L+L
Sbjct: 557 QWSTERVCAWLEDFGLAQYV-IFARQWVSSGHTLLTATPQDMEK-ELGIKHPLHRKKLVL 614
Query: 71 SVRKL 75
+V+ +
Sbjct: 615 AVKAI 619
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 34.3 bits (77), Expect = 0.15
Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 10/78 (12%)
Query: 7 LCIRRWTTKH----VAVWLKDEGFFEYVDILCNK--HRLDGITLLTLTEYDLRSPPLEIK 60
L I W +H +AVWL G +Y +L + +D IT +T DL+ + I
Sbjct: 532 LSIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFIT--DITWEDLQE--IGIT 587
Query: 61 VLGDIKRLMLSVRKLQKI 78
LG K+LML+VRKL ++
Sbjct: 588 KLGHQKKLMLAVRKLAEL 605
>gi|7706091 bifunctional apoptosis regulator [Homo sapiens]
Length = 450
Score = 31.2 bits (69), Expect = 1.3
Identities = 17/74 (22%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 9 IRRWTTKHVAVWLKDEGFFE--YVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIK 66
+ +WT + V +WL+ G + Y + ++ R++G LLTLTE + P I+ +
Sbjct: 179 VAKWTAEEVVLWLEQLGPWASLYRERFLSE-RVNGRLLLTLTEEEFSKTPYTIENSSHRR 237
Query: 67 RLMLSVRKLQKIHI 80
+++ + +++ + +
Sbjct: 238 AILMELERVKALGV 251
>gi|38016914 SAM domain- and HD domain-containing protein 1 [Homo
sapiens]
Length = 626
Score = 30.8 bits (68), Expect = 1.7
Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 10 RRWTTKHVAVWLKDEGFFEYVDILCN--KHRLDGITLLTLTEYDLRSPPLEIKVLGDIKR 67
+ W + V +L+ GF E V +L N ++ + G L L E R L + LG+ K+
Sbjct: 43 KTWGPEQVCSFLRRGGFEEPV-LLKNIRENEITGALLPCLDES--RFENLGVSSLGERKK 99
Query: 68 LMLSVRKLQKIHIDVLE 84
L+ +++L +IH+D ++
Sbjct: 100 LLSYIQRLVQIHVDTMK 116
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 30.8 bits (68), Expect = 1.7
Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Query: 46 TLTE-YDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSM 97
T+TE Y+ S + +I+RL + + KLQ +H L EM +N + M M
Sbjct: 889 TMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEM 941
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 30.8 bits (68), Expect = 1.7
Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Query: 46 TLTE-YDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSM 97
T+TE Y+ S + +I+RL + + KLQ +H L EM +N + M M
Sbjct: 914 TMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEM 966
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 30.8 bits (68), Expect = 1.7
Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Query: 46 TLTE-YDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSM 97
T+TE Y+ S + +I+RL + + KLQ +H L EM +N + M M
Sbjct: 914 TMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEM 966
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 30.4 bits (67), Expect = 2.2
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 11 RWTTKHVAVWLKDEGFFEYVDILCNKHRL-DGITLLTLTEYDLRSPPLEIKVLGDIKRLM 69
+WT + V WL ++G Y++ KH + G TLL ++ DL L IK K+L
Sbjct: 640 KWTKEQVCNWLMEQGLGSYLN--SGKHWIASGQTLLQASQQDLEK-ELGIKHSLHRKKLQ 696
Query: 70 LSVRKL 75
L+++ L
Sbjct: 697 LALQAL 702
>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
Length = 958
Score = 29.6 bits (65), Expect = 3.8
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 110 LCNGELSHDCDGPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFI 169
L N +S D DL + + Y+NG + RL PE + + S Y+F+ + I
Sbjct: 440 LGNNRISMIQDRAFGDLTNLRRLYLNGNR---IERLSPELFYGLQSLQYLFLQYNLIREI 496
Query: 170 MVIVHERVPDMQ 181
+ VP++Q
Sbjct: 497 QSGTFDPVPNLQ 508
>gi|9256612 protocadherin beta 2 precursor [Homo sapiens]
Length = 798
Score = 28.9 bits (63), Expect = 6.5
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 45 LTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSMTPFISAL 104
LTLT D SPP L I+ ++ + +L E+ DSP+GS +SA
Sbjct: 212 LTLTALDGGSPPRSGTALVRIE--VVDINDNVPEFAKLLYEVQIPEDSPVGSQVAIVSA- 268
Query: 105 QSTDWLCNGELSH 117
+ D NGE+S+
Sbjct: 269 RDLDIGTNGEISY 281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.142 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,932,071
Number of Sequences: 37866
Number of extensions: 548852
Number of successful extensions: 1485
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1463
Number of HSP's gapped (non-prelim): 25
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.