Guide to the Human Genome
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Search of human proteins with 21389517

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389517 gammaN-crystallin [Homo sapiens]
         (182 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389517 gammaN-crystallin [Homo sapiens]                          395   e-110
gi|16936542 crystallin, beta A2 [Homo sapiens]                        109   1e-24
gi|16936540 crystallin, beta A2 [Homo sapiens]                        109   1e-24
gi|7019357 crystallin, beta A2 [Homo sapiens]                         109   1e-24
gi|12056461 crystallin, beta A3 [Homo sapiens]                        103   1e-22
gi|4503061 crystallin, beta B1 [Homo sapiens]                          99   2e-21
gi|8922120 crystallin, gamma S [Homo sapiens]                          97   8e-21
gi|10518338 crystallin, gamma C [Homo sapiens]                         95   3e-20
gi|148491074 crystallin, gamma B [Homo sapiens]                        93   1e-19
gi|13377002 crystallin, gamma D [Homo sapiens]                         92   2e-19
gi|4758074 crystallin, beta B3 [Homo sapiens]                          91   5e-19
gi|4503059 crystallin, beta A4 [Homo sapiens]                          85   3e-17
gi|148491057 crystallin, gamma A [Homo sapiens]                        83   1e-16
gi|4503063 crystallin, beta B2 [Homo sapiens]                          81   6e-16
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi...    72   2e-13
gi|62988361 absent in melanoma 1 [Homo sapiens]                        67   1e-11
gi|89886227 absent in melanoma 1-like [Homo sapiens]                   60   1e-09
gi|22748711 hypothetical protein LOC122046 [Homo sapiens]              28   4.4  
gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]          28   5.7  
gi|150378498 fragile site-associated protein [Homo sapiens]            27   9.7  

>gi|21389517 gammaN-crystallin [Homo sapiens]
          Length = 182

 Score =  395 bits (1015), Expect = e-110
 Identities = 182/182 (100%), Positives = 182/182 (100%)

Query: 1   MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ 60
           MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ
Sbjct: 1   MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ 60

Query: 61  QFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQ 120
           QFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQ
Sbjct: 61  QFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQ 120

Query: 121 SRGWVKNCVNTIKVYGDGAAWSPRSFGAEDFQLSSSLQSDQGPEEATTKPATTQPPFLTA 180
           SRGWVKNCVNTIKVYGDGAAWSPRSFGAEDFQLSSSLQSDQGPEEATTKPATTQPPFLTA
Sbjct: 121 SRGWVKNCVNTIKVYGDGAAWSPRSFGAEDFQLSSSLQSDQGPEEATTKPATTQPPFLTA 180

Query: 181 NL 182
           NL
Sbjct: 181 NL 182


>gi|16936542 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  109 bits (272), Expect = 1e-24
 Identities = 58/140 (41%), Positives = 82/140 (58%), Gaps = 9/140 (6%)

Query: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
           +TL++ + F G++  +  DC N  +RG + RV S+ VE+G WV F +PDF+GQQFILE G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 68  DYPDFFRWNSHSDH----MGSCRPV--GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
           DYP +  W+  S H    + S RPV    H +  R+ +FEG NF G   + ++D P L S
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132

Query: 122 RGWVKNCVNTIKVYGDGAAW 141
            GW    V ++KV     AW
Sbjct: 133 MGWASKDVGSLKV--SSGAW 150



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 23/60 (38%), Positives = 39/60 (65%), Gaps = 1/60 (1%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNR-VNSIHVESGAWVCFNHPDFRGQQFILE 65
           ++TL+EG +F G K ++  D  +    G+ ++ V S+ V SGAWV + +P +RG Q++LE
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166


>gi|16936540 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  109 bits (272), Expect = 1e-24
 Identities = 58/140 (41%), Positives = 82/140 (58%), Gaps = 9/140 (6%)

Query: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
           +TL++ + F G++  +  DC N  +RG + RV S+ VE+G WV F +PDF+GQQFILE G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 68  DYPDFFRWNSHSDH----MGSCRPV--GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
           DYP +  W+  S H    + S RPV    H +  R+ +FEG NF G   + ++D P L S
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132

Query: 122 RGWVKNCVNTIKVYGDGAAW 141
            GW    V ++KV     AW
Sbjct: 133 MGWASKDVGSLKV--SSGAW 150



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 23/60 (38%), Positives = 39/60 (65%), Gaps = 1/60 (1%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNR-VNSIHVESGAWVCFNHPDFRGQQFILE 65
           ++TL+EG +F G K ++  D  +    G+ ++ V S+ V SGAWV + +P +RG Q++LE
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166


>gi|7019357 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  109 bits (272), Expect = 1e-24
 Identities = 58/140 (41%), Positives = 82/140 (58%), Gaps = 9/140 (6%)

Query: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
           +TL++ + F G++  +  DC N  +RG + RV S+ VE+G WV F +PDF+GQQFILE G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 68  DYPDFFRWNSHSDH----MGSCRPV--GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
           DYP +  W+  S H    + S RPV    H +  R+ +FEG NF G   + ++D P L S
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132

Query: 122 RGWVKNCVNTIKVYGDGAAW 141
            GW    V ++KV     AW
Sbjct: 133 MGWASKDVGSLKV--SSGAW 150



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 23/60 (38%), Positives = 39/60 (65%), Gaps = 1/60 (1%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNR-VNSIHVESGAWVCFNHPDFRGQQFILE 65
           ++TL+EG +F G K ++  D  +    G+ ++ V S+ V SGAWV + +P +RG Q++LE
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166


>gi|12056461 crystallin, beta A3 [Homo sapiens]
          Length = 215

 Score =  103 bits (256), Expect = 1e-22
 Identities = 55/140 (39%), Positives = 82/140 (58%), Gaps = 8/140 (5%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           KIT+Y+ ++F G+++E    C N  +R F N V S+ VESGAW+ + H  F GQQFILE 
Sbjct: 32  KITIYDQENFQGKRMEFTSSCPNVSERSFDN-VRSLKVESGAWIGYEHTSFCGQQFILER 90

Query: 67  GDYPDFFRWNS----HSDHMGSCRPV-GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
           G+YP +  W+     H + + S RP+   + +  ++ IFE  NF G+  E  +D P LQ+
Sbjct: 91  GEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQA 150

Query: 122 RGWVKNCVNTIKVYGDGAAW 141
            GW  N V ++K+     AW
Sbjct: 151 MGWFNNEVGSMKI--QSGAW 168



 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 32/81 (39%), Positives = 51/81 (62%), Gaps = 5/81 (6%)

Query: 4   RSGKITLYEGKHFTGQKLEVFGDCDNFQDRG-FMNRVNSIHVESGAWVCFNHPDFRGQQF 62
           +  K+T++E ++F G++ E+  D  + Q  G F N V S+ ++SGAWVC+ +P +RG Q+
Sbjct: 122 KESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQY 181

Query: 63  ILE----HGDYPDFFRWNSHS 79
           ILE     GDY  +  W SH+
Sbjct: 182 ILECDHHGGDYKHWREWGSHA 202


>gi|4503061 crystallin, beta B1 [Homo sapiens]
          Length = 252

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 52/131 (39%), Positives = 81/131 (61%), Gaps = 5/131 (3%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           ++ ++E ++F G++ E  G+C N  DRGF +RV SI V +G WV F   +FRG+ FILE 
Sbjct: 60  RLVVFELENFQGRRAEFSGECSNLADRGF-DRVRSIIVSAGPWVAFEQSNFRGEMFILEK 118

Query: 67  GDYPDFFRWNS--HSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFL-EDSPFLQSRG 123
           G+YP +  W+S   SD + S RP+ M  +  ++ +FEG NF G  +E   +D+P L   G
Sbjct: 119 GEYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYG 178

Query: 124 WVKNCVNTIKV 134
           +  + V ++KV
Sbjct: 179 F-SDRVGSVKV 188



 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 1   MAQRSGKITLYEGKHFTGQKLEVFGD-CDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRG 59
           M  +  KI+L+EG +F G  +E+ GD   +    GF +RV S+ V SG WV + +P +RG
Sbjct: 144 MDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRG 203

Query: 60  QQFILEHGDYPDFFRWNSHSDHMGSCR 86
            Q++LE GD+  +  W +    M S R
Sbjct: 204 YQYLLEPGDFRHWNEWGAFQPQMQSLR 230


>gi|8922120 crystallin, gamma S [Homo sapiens]
          Length = 178

 Score = 97.1 bits (240), Expect = 8e-21
 Identities = 46/123 (37%), Positives = 73/123 (59%), Gaps = 3/123 (2%)

Query: 1   MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ 60
           M++   KIT YE K+F G++ +   DC +F    +++R NSI VE G W  +  P+F G 
Sbjct: 1   MSKTGTKITFYEDKNFQGRRYDCDCDCADFHT--YLSRCNSIKVEGGTWAVYERPNFAGY 58

Query: 61  QFILEHGDYPDFFRWNSHSDHMGSCRPVGM-HGEHFRLEIFEGCNFTGQCLEFLEDSPFL 119
            +IL  G+YP++ RW   +D + SCR V +  G  ++++IFE  +F+GQ  E  ED P +
Sbjct: 59  MYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSI 118

Query: 120 QSR 122
             +
Sbjct: 119 MEQ 121



 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 24/82 (29%), Positives = 44/82 (53%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           KI ++E   F+GQ  E   DC +  ++  M  ++S  V  G W+ +  P++RG+Q++L+ 
Sbjct: 95  KIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDK 154

Query: 67  GDYPDFFRWNSHSDHMGSCRPV 88
            +Y     W + S  + S R +
Sbjct: 155 KEYRKPIDWGAASPAVQSFRRI 176


>gi|10518338 crystallin, gamma C [Homo sapiens]
          Length = 174

 Score = 95.1 bits (235), Expect = 3e-20
 Identities = 47/117 (40%), Positives = 68/117 (58%), Gaps = 3/117 (2%)

Query: 6   GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
           GKIT YE + F G+  E   DC N Q   + +R NSI VESG W+ +  P+++GQQ++L 
Sbjct: 2   GKITFYEDRAFQGRSYETTTDCPNLQP--YFSRCNSIRVESGCWMLYERPNYQGQQYLLR 59

Query: 66  HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSR 122
            G+YPD+ +W   SD + SC  +     H RL ++E  +  G  +E  ED P +Q R
Sbjct: 60  RGEYPDYQQWMGLSDSIRSCCLIPQTVSH-RLRLYEREDHKGLMMELSEDCPSIQDR 115



 Score = 60.5 bits (145), Expect = 8e-10
 Identities = 28/84 (33%), Positives = 46/84 (54%)

Query: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64
           S ++ LYE +   G  +E+  DC + QDR  ++ + S+HV  G WV +  P++RG+Q++L
Sbjct: 87  SHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLL 146

Query: 65  EHGDYPDFFRWNSHSDHMGSCRPV 88
              +Y     W +     GS R V
Sbjct: 147 RPQEYRRCQDWGAMDAKAGSLRRV 170


>gi|148491074 crystallin, gamma B [Homo sapiens]
          Length = 175

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 44/117 (37%), Positives = 66/117 (56%), Gaps = 2/117 (1%)

Query: 6   GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
           GKIT YE + F G+  E   DC N Q   + +R NSI VESG W+ +  P+++G Q+ L 
Sbjct: 2   GKITFYEDRAFQGRSYECTTDCPNLQP--YFSRCNSIRVESGCWMIYERPNYQGHQYFLR 59

Query: 66  HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSR 122
            G+YPD+ +W   SD + SC  +  H   +R++I++     GQ  E  +D   +Q R
Sbjct: 60  RGEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDR 116



 Score = 63.9 bits (154), Expect = 7e-11
 Identities = 26/82 (31%), Positives = 49/82 (59%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           ++ +Y+     GQ  E+  DC + QDR  +  ++S++V  G+W+ +  P++RG+Q++L  
Sbjct: 90  RMKIYDRDELRGQMSELTDDCISVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRP 149

Query: 67  GDYPDFFRWNSHSDHMGSCRPV 88
           G+Y  F  W + +  +GS R V
Sbjct: 150 GEYRRFLDWGAPNAKVGSLRRV 171


>gi|13377002 crystallin, gamma D [Homo sapiens]
          Length = 174

 Score = 92.4 bits (228), Expect = 2e-19
 Identities = 47/117 (40%), Positives = 67/117 (57%), Gaps = 3/117 (2%)

Query: 6   GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
           GKITLYE + F G+  E   D  N Q   +++R NS  V+SG W+ +  P++ G Q+ L 
Sbjct: 2   GKITLYEDRGFQGRHYECSSDHPNLQP--YLSRCNSARVDSGCWMLYEQPNYSGLQYFLR 59

Query: 66  HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSR 122
            GDY D  +W   SD + SCR +   G H R+ ++E  ++ GQ +EF ED   LQ R
Sbjct: 60  RGDYADHQQWMGLSDSVRSCRLIPHSGSH-RIRLYEREDYRGQMIEFTEDCSCLQDR 115



 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 31/84 (36%), Positives = 50/84 (59%)

Query: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64
           S +I LYE + + GQ +E   DC   QDR   N ++S++V  G+WV +   ++RG+Q++L
Sbjct: 87  SHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLL 146

Query: 65  EHGDYPDFFRWNSHSDHMGSCRPV 88
             GDY  +  W + +  +GS R V
Sbjct: 147 MPGDYRRYQDWGATNARVGSLRRV 170


>gi|4758074 crystallin, beta B3 [Homo sapiens]
          Length = 211

 Score = 90.9 bits (224), Expect = 5e-19
 Identities = 47/123 (38%), Positives = 75/123 (60%), Gaps = 4/123 (3%)

Query: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64
           S K+ LYE ++F G++ E+  +C +  D   + +V SI VESG W+ F    FRG+QF+L
Sbjct: 23  SYKVILYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81

Query: 65  EHGDYPDFFRWNS--HSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDS-PFLQS 121
           E GDYP +  W++   SD + S RP+ +   H +L +FE   F+G+ +E ++D  P L +
Sbjct: 82  EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWA 141

Query: 122 RGW 124
            G+
Sbjct: 142 HGF 144



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 1/83 (1%)

Query: 7   KITLYEGKHFTGQKLEVFGD-CDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
           K+ L+E   F+G+K+E+  D   +    GF +RV S+   +G WV +  P +RG+Q++ E
Sbjct: 115 KLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174

Query: 66  HGDYPDFFRWNSHSDHMGSCRPV 88
            G+Y  +  W++    + S R +
Sbjct: 175 RGEYRHWNEWDASQPQLQSVRRI 197


>gi|4503059 crystallin, beta A4 [Homo sapiens]
          Length = 196

 Score = 85.1 bits (209), Expect = 3e-17
 Identities = 55/152 (36%), Positives = 79/152 (51%), Gaps = 9/152 (5%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           K+ +++   F G++ E   +C +  + GF   V S+ V SGAWV F H  F+GQQ+ILE 
Sbjct: 13  KMVVWDEDGFQGRRHEFTAECPSVLELGF-ETVRSLKVLSGAWVGFEHAGFQGQQYILER 71

Query: 67  GDYPDFFRWNSH----SDHMGSCRPVG-MHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
           G+YP +  W  +    ++ + S RP    +    RL IFE  NF G+  E  +D P LQ+
Sbjct: 72  GEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQA 131

Query: 122 RGWVKNCVNTIKVYGDGAAWSPRSF-GAEDFQ 152
            GW  N V +  V+    AW    F G   FQ
Sbjct: 132 MGWEGNEVGSFHVH--SGAWVCSQFPGYRGFQ 161



 Score = 68.2 bits (165), Expect = 4e-12
 Identities = 34/81 (41%), Positives = 48/81 (59%), Gaps = 5/81 (6%)

Query: 4   RSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFM-NRVNSIHVESGAWVCFNHPDFRGQQF 62
           R  ++T++E ++F G+K E+  D  + Q  G+  N V S HV SGAWVC   P +RG Q+
Sbjct: 103 RDSRLTIFEQENFLGKKGELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQY 162

Query: 63  ILE----HGDYPDFFRWNSHS 79
           +LE     GDY  F  W SH+
Sbjct: 163 VLECDHHSGDYKHFREWGSHA 183


>gi|148491057 crystallin, gamma A [Homo sapiens]
          Length = 174

 Score = 83.2 bits (204), Expect = 1e-16
 Identities = 40/110 (36%), Positives = 60/110 (54%), Gaps = 3/110 (2%)

Query: 6   GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
           GKIT YE + F G+      DC N   R + +R NSI V+SG W+ +  P+++G Q+ L 
Sbjct: 2   GKITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59

Query: 66  HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLED 115
            G YPD+  W   SD + SCR +  H    +L ++E  ++ G   E  +D
Sbjct: 60  RGKYPDYQHWMGLSDSVQSCRII-PHTSSHKLRLYERDDYRGLMSELTDD 108



 Score = 57.8 bits (138), Expect = 5e-09
 Identities = 28/84 (33%), Positives = 43/84 (51%)

Query: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64
           S K+ LYE   + G   E+  DC    +   +  + S+HV  G WV +  P++RG+Q++L
Sbjct: 87  SHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL 146

Query: 65  EHGDYPDFFRWNSHSDHMGSCRPV 88
             GDY  +  W      +GS R V
Sbjct: 147 RPGDYRRYHDWGGADAKVGSLRRV 170


>gi|4503063 crystallin, beta B2 [Homo sapiens]
          Length = 205

 Score = 80.9 bits (198), Expect = 6e-16
 Identities = 39/131 (29%), Positives = 78/131 (59%), Gaps = 5/131 (3%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           KI ++E ++F G   E+ G C N ++ G + +  S+ V++G WV +   + +G+QF+ E 
Sbjct: 18  KIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQANCKGEQFVFEK 76

Query: 67  GDYPDFFRWNS--HSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDS-PFLQSRG 123
           G+YP +  W S   +D + S RP+ +  +  ++ ++E  NFTG+ +E ++D  P   + G
Sbjct: 77  GEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHG 136

Query: 124 WVKNCVNTIKV 134
           + +  V++++V
Sbjct: 137 YQEK-VSSVRV 146



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 30/66 (45%), Positives = 45/66 (68%), Gaps = 1/66 (1%)

Query: 7   KITLYEGKHFTGQKLEVFGD-CDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65
           KI LYE  +FTG+K+E+  D   +F   G+  +V+S+ V+SG WV + +P +RG Q++LE
Sbjct: 108 KIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLE 167

Query: 66  HGDYPD 71
            GDY D
Sbjct: 168 KGDYKD 173


>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
           sapiens]
          Length = 1022

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 6/120 (5%)

Query: 8   ITLYEGKHFTGQKLEVFG-DCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           +TL+E    +G+ +++   +  + ++ GF ++  SIHV+SG WV +    F G+Q+ILE 
Sbjct: 626 VTLFESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEK 685

Query: 67  GDYPDFFRWNSHSDHMGSCRPV-----GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
           G Y  FF W   ++ + S RP+     G++     L+ F    F G+C++F E++  L S
Sbjct: 686 GKYKCFFDWGGSNNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEETSDLTS 745



 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 27/69 (39%), Positives = 38/69 (55%), Gaps = 4/69 (5%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDN----FQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQF 62
           K+ +YE  HF GQ  E     D+     ++ G  +R+ SI V  G WV +    F+GQQF
Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591

Query: 63  ILEHGDYPD 71
           +LE GD+ D
Sbjct: 592 LLEEGDFED 600



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 23/94 (24%), Positives = 48/94 (51%), Gaps = 7/94 (7%)

Query: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
           I+L+  +H  G++L +    ++  ++       S+ V+SG W+ +   +F G+Q +L   
Sbjct: 806 ISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLRPN 865

Query: 68  DYPD---FFRWNSHSDHMGSCRPVGMHGEHFRLE 98
           + P+   F RW +    +GS RP+     + R++
Sbjct: 866 EIPNWTAFSRWKT----IGSLRPMKQPAVYIRIK 895



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 4   RSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFI 63
           R GK+ +Y+  H +  K EV+ +  +     F N V  I V  G W+ +  P FRGQ+ +
Sbjct: 345 RPGKMVIYD-LHESTYKQEVYCNIPDATSWSFPNGV-LIKVVRGCWILYEKPHFRGQKCV 402

Query: 64  LEHGD 68
           LE G+
Sbjct: 403 LEEGE 407



 Score = 36.2 bits (82), Expect = 0.016
 Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 14/140 (10%)

Query: 41  SIHVESGAWVCFNHPDFRGQQFILEHGDYPDFFRWNSHSDHMGSCRPVGMHG------EH 94
           S  V+SG W+ +   +F+GQ  +LE     D   +   +  M S  P+ M G       +
Sbjct: 475 SFTVKSGVWLAYPDINFKGQATVLEE----DHGLFEISTAEMKSLHPLQMGGLKVEMPMN 530

Query: 95  FRLEIFEGCNFTGQCLEFLE--DS--PFLQSRGWVKNCVNTIKVYGDGAAWSPRSFGAED 150
            ++ I+E  +F GQ  EF E  DS   FL++ G      +   + G   A+    F  + 
Sbjct: 531 LKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQ 590

Query: 151 FQLSSSLQSDQGPEEATTKP 170
           F L      D     A + P
Sbjct: 591 FLLEEGDFEDSNACGALSSP 610


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 6/114 (5%)

Query: 4    RSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFI 63
            R   I L+      G     F D +  Q  G M +  S+ V  G W+ +  P F+G  FI
Sbjct: 1121 RVSHIDLFTEPEGLGILSSYFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFI 1180

Query: 64   LEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHF------RLEIFEGCNFTGQCLE 111
            LE G+YPD   W++ + ++GS RP+ M G         ++ ++E   F G+C+E
Sbjct: 1181 LEPGEYPDLSFWDTEAAYIGSMRPLKMGGRKVEFPTDPKVVVYEKPFFEGKCVE 1234



 Score = 63.5 bits (153), Expect = 9e-11
 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 7/126 (5%)

Query: 10   LYEGKHF--TGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
            +Y  K+F   G  ++V G   N ++ G+  +  SI+V SG WV + +PDF G+Q+IL+ G
Sbjct: 1323 MYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKG 1382

Query: 68   DYPDFFRWNSHSDHMGSCRPVGMHG-----EHFRLEIFEGCNFTGQCLEFLEDSPFLQSR 122
             Y  F  W   +  + S +P+ +          ++ +F    F G    F E +  +   
Sbjct: 1383 FYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHSQSFEETTSQIDDS 1442

Query: 123  GWVKNC 128
               K+C
Sbjct: 1443 FSTKSC 1448



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 29/90 (32%), Positives = 51/90 (56%), Gaps = 1/90 (1%)

Query: 8    ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
            I L+E + F G+K+E+  +  N +  GF  ++ S+ V  G WV + +  +RG+QF+L   
Sbjct: 1504 IILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPA 1563

Query: 68   DYPDFFRWNSHSDHMGSCRPVGMHGEHFRL 97
            + P+++ + S    +GS RP      +FRL
Sbjct: 1564 EVPNWYEF-SGCRQIGSLRPFVQKRIYFRL 1592



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 12/94 (12%)

Query: 7    KITLYEGKHFTGQKLEV-FGDCDNFQDRGFMNR-----------VNSIHVESGAWVCFNH 54
            K+ +YE   F G+ +E+  G C    + G               V S+ V  G WV +  
Sbjct: 1219 KVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEK 1278

Query: 55   PDFRGQQFILEHGDYPDFFRWNSHSDHMGSCRPV 88
            P F G Q++LE G+Y D+  W  ++  + S RP+
Sbjct: 1279 PGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPI 1312



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 7/147 (4%)

Query: 3    QRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQF 62
            +R  +I L+    F G   + F +  +  D  F  +  S  V  G+WV ++  +F G Q+
Sbjct: 1412 RRRNQIHLFSEPQFQGHS-QSFEETTSQIDDSFSTK--SCRVSGGSWVVYDGENFTGNQY 1468

Query: 63   ILEHGDYPDFFRWN-SHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
            +LE G YP              S R + +      + +FE  +F G+ +E   ++  L+S
Sbjct: 1469 VLEEGHYPCLSAMGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETVNLRS 1528

Query: 122  RGWVKNCVNTIKVYGDGAAWSPRSFGA 148
             G+    + +++V   G  W    +G+
Sbjct: 1529 LGF-NTQIRSVQVI--GGIWVTYEYGS 1552



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 4    RSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFI 63
            R GK+ +Y     + + +EVF D  +      ++ V  I V  G W+ +  P+F G    
Sbjct: 1020 RPGKVVIYSEPDVSEKCIEVFSDIQDCSSWS-LSPVILIKVVRGCWILYEQPNFEGHSIP 1078

Query: 64   LEHGD 68
            LE G+
Sbjct: 1079 LEEGE 1083


>gi|89886227 absent in melanoma 1-like [Homo sapiens]
          Length = 616

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 5/116 (4%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQD-----RGFMNRVNSIHVESGAWVCFNHPDFRGQQ 61
           +  +YE   F G+  EV  D  N Q         +  V S+ V  G WV +    FRG Q
Sbjct: 124 RAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQ 183

Query: 62  FILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSP 117
           ++LE G+YPD+  W  + + + S R +        + +FE  +F G  +E  +  P
Sbjct: 184 YLLEEGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEVSKALP 239



 Score = 57.0 bits (136), Expect = 9e-09
 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 5/126 (3%)

Query: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
           + L+E   F G  +EV     + +         +IHV SG WV +    F G+Q++LE G
Sbjct: 219 VVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKG 278

Query: 68  DYPDFFRWNSHSDHMGSCRP---VGMHGEHF--RLEIFEGCNFTGQCLEFLEDSPFLQSR 122
            Y +   W + +  + S +P   VG H  HF  ++++F   +F G    F +D   L + 
Sbjct: 279 VYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPAS 338

Query: 123 GWVKNC 128
              ++C
Sbjct: 339 FRPQSC 344



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 28/90 (31%), Positives = 50/90 (55%), Gaps = 1/90 (1%)

Query: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
           I LY  + F G+++E+  +  + Q  GF N V S+ ++ G WV   H DFRG+Q+++   
Sbjct: 400 IFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSC 459

Query: 68  DYPDFFRWNSHSDHMGSCRPVGMHGEHFRL 97
           +  ++  + S +  +GS  P+     +FRL
Sbjct: 460 EITNWLTY-SGTQRVGSLYPIKQRRVYFRL 488



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 8/121 (6%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           +I+L+  +   G+++++     N Q      +V S  V +G W+ +  P F    +ILE 
Sbjct: 29  EISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEP 88

Query: 67  GDYPDFFRWNSHSDHMGSCRP-------VGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFL 119
           G+YP    W +    +GS +P       V   GE  R  ++E   F G+  E   D   L
Sbjct: 89  GEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGEP-RAVVYEAPGFQGRSWEVSRDIYNL 147

Query: 120 Q 120
           Q
Sbjct: 148 Q 148



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 5/131 (3%)

Query: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
           KI L+    F G     F D        F  R  S  V  G+W+ F+  +F G Q IL  
Sbjct: 312 KIQLFSRPDFLGDHFS-FEDDQAALPASF--RPQSCRVHGGSWILFDETNFEGDQHILSE 368

Query: 67  GDYPDFFRWNS-HSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSRGWV 125
           G++P         S  +GS + V +H     + ++    F G+ +E   +   LQ+ G+ 
Sbjct: 369 GEFPTLTAMGCLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGF- 427

Query: 126 KNCVNTIKVYG 136
            N V ++++ G
Sbjct: 428 NNHVLSVRIKG 438


>gi|22748711 hypothetical protein LOC122046 [Homo sapiens]
          Length = 289

 Score = 28.1 bits (61), Expect = 4.4
 Identities = 20/71 (28%), Positives = 26/71 (36%), Gaps = 16/71 (22%)

Query: 63  ILEHGDYPDFFRWNSHSDH----MGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPF 118
           IL    Y D + W SHS        + R +  H  H   +I            FL   P 
Sbjct: 66  ILNQTQYSDEYTWKSHSKEDLIKTETSRGIKSHKSHLNEDI------------FLWTLPH 113

Query: 119 LQSRGWVKNCV 129
            Q  G +KNC+
Sbjct: 114 CQQTGTLKNCL 124


>gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]
          Length = 873

 Score = 27.7 bits (60), Expect = 5.7
 Identities = 15/51 (29%), Positives = 23/51 (45%)

Query: 126 KNCVNTIKVYGDGAAWSPRSFGAEDFQLSSSLQSDQGPEEATTKPATTQPP 176
           +N   T    G G + S         Q SS +++ QGP +  +K  TT+ P
Sbjct: 718 RNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSP 768


>gi|150378498 fragile site-associated protein [Homo sapiens]
          Length = 5005

 Score = 26.9 bits (58), Expect = 9.7
 Identities = 11/35 (31%), Positives = 18/35 (51%)

Query: 41   SIHVESGAWVCFNHPDFRGQQFILEHGDYPDFFRW 75
            S+H       CF+ P+FR + + L H + P+   W
Sbjct: 4657 SLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW 4691


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,056,410
Number of Sequences: 37866
Number of extensions: 375099
Number of successful extensions: 833
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 750
Number of HSP's gapped (non-prelim): 51
length of query: 182
length of database: 18,247,518
effective HSP length: 96
effective length of query: 86
effective length of database: 14,612,382
effective search space: 1256664852
effective search space used: 1256664852
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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