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Search of human proteins with 21361378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
(918 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens] 1895 0.0
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens] 1895 0.0
gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens] 431 e-120
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun... 429 e-120
gi|44662838 aminomethyltransferase [Homo sapiens] 70 7e-12
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom... 60 7e-09
gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo s... 47 8e-05
gi|60499001 pipecolic acid oxidase [Homo sapiens] 39 0.022
gi|239753433 PREDICTED: hypothetical protein XP_002345652 [Homo ... 32 2.1
gi|112382257 InaD-like [Homo sapiens] 32 2.7
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 32 2.7
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 32 2.7
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 32 2.7
gi|8923900 cytidine monophospho-N-acetylneuraminic acid syntheta... 31 4.6
gi|146134388 YLP motif containing 1 [Homo sapiens] 31 4.6
gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens] 31 6.1
>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
Length = 918
Score = 1895 bits (4908), Expect = 0.0
Identities = 918/918 (100%), Positives = 918/918 (100%)
Query: 1 MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS
Sbjct: 1 MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
Query: 61 RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120
RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD
Sbjct: 61 RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120
Query: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180
VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH
Sbjct: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180
Query: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240
VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI
Sbjct: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240
Query: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300
RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER
Sbjct: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300
Query: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360
IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH
Sbjct: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360
Query: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420
IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC
Sbjct: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420
Query: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480
GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG
Sbjct: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480
Query: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540
RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR
Sbjct: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540
Query: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600
LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR
Sbjct: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600
Query: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660
PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI
Sbjct: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660
Query: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720
TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH
Sbjct: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720
Query: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780
LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW
Sbjct: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780
Query: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE
Sbjct: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
Query: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ
Sbjct: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
Query: 901 AHLKSPFDPNNKRVKGIY 918
AHLKSPFDPNNKRVKGIY
Sbjct: 901 AHLKSPFDPNNKRVKGIY 918
>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
Length = 918
Score = 1895 bits (4908), Expect = 0.0
Identities = 918/918 (100%), Positives = 918/918 (100%)
Query: 1 MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS
Sbjct: 1 MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
Query: 61 RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120
RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD
Sbjct: 61 RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120
Query: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180
VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH
Sbjct: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180
Query: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240
VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI
Sbjct: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240
Query: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300
RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER
Sbjct: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300
Query: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360
IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH
Sbjct: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360
Query: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420
IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC
Sbjct: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420
Query: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480
GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG
Sbjct: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480
Query: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540
RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR
Sbjct: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540
Query: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600
LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR
Sbjct: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600
Query: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660
PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI
Sbjct: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660
Query: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720
TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH
Sbjct: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720
Query: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780
LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW
Sbjct: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780
Query: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE
Sbjct: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
Query: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ
Sbjct: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
Query: 901 AHLKSPFDPNNKRVKGIY 918
AHLKSPFDPNNKRVKGIY
Sbjct: 901 AHLKSPFDPNNKRVKGIY 918
>gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens]
Length = 866
Score = 431 bits (1108), Expect = e-120
Identities = 279/845 (33%), Positives = 433/845 (51%), Gaps = 66/845 (7%)
Query: 67 ANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELL 126
A V+IGGG +G YHLAK GM VLLE+ LT+G+TWH AGL P + ++ +
Sbjct: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG-INLKKI 108
Query: 127 AHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAE 186
+ + +LEEETG G+ Q G + +A+ R+DE+K M+ + E +++ P +
Sbjct: 109 HYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEK 168
Query: 187 TKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDD 246
+ ++PL+N++ + LY P DG +DP LA A GA + PVT ++ +D
Sbjct: 169 IQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228
Query: 247 FGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQ- 305
VET GS++ +VN AG WA VG+M G++ PL+ + H YVVT I ++
Sbjct: 229 -----TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKA 283
Query: 306 ---NMPNVRDHDASVYLRLQGDALSVGGYEANPIF-----W--EEVSDKFAFGLFDLDWE 355
+P +RD + S YLR + D L G YE+ W V F LF+ D +
Sbjct: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLD 343
Query: 356 VFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMM 415
+HI+ A+ VPVL+K I + V GP +++PD P++G +R +++ GF G++
Sbjct: 344 RIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGY-GII 402
Query: 416 LGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHD 475
GG G+ L+ WI+HG P D+ D R+ T ++ ++ ESY N V +P +
Sbjct: 403 HAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT--QYTEAKARESYGFNNIVGYPKE 460
Query: 476 EPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHED 535
E AGR +R + L C GWE+P WF+ G +D
Sbjct: 461 ERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPG------------------QD 502
Query: 536 YAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFS 595
YR +F + + E AV D+S FGKF + G D+ + D LF
Sbjct: 503 TQYRP------SFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLF- 555
Query: 596 ADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQH 655
A+V G T + ML +G ++LTVS +P + L G H
Sbjct: 556 ANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGE-------------FLLITGSGSELH 602
Query: 656 NWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLL 715
+ I ++ + +++LG++ + GP +R +LQ++ DLS++ F F K L
Sbjct: 603 DLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSL 662
Query: 716 RAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEK 775
+ + V A+R+S+ GELGWEL+ + V +Y A+M AG + G+ N G A+++L +EK
Sbjct: 663 KVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEK 722
Query: 776 GYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTM-EDKV 834
+R W ++ D +PLEAGL + KL P F+G++AL+Q +A GL+RRLVC T+ D V
Sbjct: 723 AFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDV 782
Query: 835 PMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMG 894
G E+IW NG+VVG+ + ++I K++A+ Y+ PV L V +E +G
Sbjct: 783 DPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYV------PVQLSEV-GQQVEVELLG 835
Query: 895 VTYGA 899
Y A
Sbjct: 836 KNYPA 840
>gi|194306651 pyruvate dehydrogenase phosphatase regulatory subunit
[Homo sapiens]
Length = 879
Score = 429 bits (1102), Expect = e-120
Identities = 284/889 (31%), Positives = 451/889 (50%), Gaps = 68/889 (7%)
Query: 37 EKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLL 96
+++ P + + ++ A+ S LP+ A VV+ GGG G YHL+K+G VLL
Sbjct: 13 QRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLL 72
Query: 97 ERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIA 156
E+ RL +G+T AG+L R +E ++ ++ ++ +LE+ETG+ TG+ + G +F+A
Sbjct: 73 EQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYY-QLEQETGIQTGYTRTGSIFLA 131
Query: 157 SNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGT 216
+ RL KR+ + G+ S ++SP + L+ L+NV DL G ++VP D + A
Sbjct: 132 QTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADV 191
Query: 217 CTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWAS 276
LA AAS G Q+ + V + V +V GVET G I+ VNCAG WA
Sbjct: 192 ALALASAASQNGVQIYDRTSVLHVMVKKG-----QVTGVETDKGQIECQYFVNCAGQWAY 246
Query: 277 AVG--RMAGVKVPLVAMHHAYVVTERIEGI--QNMPNVRDHDASVYLR-LQGDALSVGGY 331
+G V +PL A H Y++T +E + P + D D +Y+R QG LS GG+
Sbjct: 247 ELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGILS-GGF 305
Query: 332 EANPI-FWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDH 390
E NP + E ++ DW+ F + + R+P LE I V PE+FTPD
Sbjct: 306 EKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDM 365
Query: 391 KPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLT 450
+ +MGE+P ++G+F+ G NSAG+ GGG G+ LA W++HG P +++ D++RF +L
Sbjct: 366 RCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF-GALQ 424
Query: 451 DHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGW 510
++R R E Y + P + GR +R PL++ L QG + E+HG+ERP +
Sbjct: 425 SSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKY 484
Query: 511 FHPRGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEY--TFAFPPHHDTIKKECLACRGAA 568
F P + LLA E TF P D ++ E C+ A
Sbjct: 485 FVPPD-----------------------KDLLALEQSKTFYKPDWFDIVESEVKCCKEAV 521
Query: 569 AVFDMSYFGKFYL--VGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRL 626
V DMS F KF + G A + +LFS D+ P G V+T MLN GG E+D +++RL
Sbjct: 522 CVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARL 581
Query: 627 APSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQ 686
+++ H W+ + + + S L D + +++
Sbjct: 582 -------------NKRSFFMISPTDQQVHCWAWLKKHM-PKDSNLLLEDVTWKYTALNLI 627
Query: 687 GPASRAILQEVLDADLSNEAFPFSTHKLLRAA-GHLVRAMRLSFVGELGWELHIPKASCV 745
GP + +L E+ A ++ + FP K + + +R M ++ GE G+ L+IP +
Sbjct: 628 GPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYAL 687
Query: 746 PVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPV 805
VY VM+ G K+G+ NAGY A+ SL IEK + W D+ +PLE G KL+ +
Sbjct: 688 HVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGM 747
Query: 806 PFLGREALEQQRAAGLRRRLVCFTMEDK------VPMFGLEAIWRNGQVVGHVRRADFGF 859
F+GR+AL QQ+ G+ +RL F ++D P +G E I+RNGQ VG + + +
Sbjct: 748 DFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWG-EPIYRNGQYVGKTTSSAYSY 806
Query: 860 AIDKTIAYGYIHDPSGGP-----VSLDFVKSGDYALERMGVTYGAQAHL 903
++++ + G++H+ S V+ DF+ G+Y ++ G + A+A L
Sbjct: 807 SLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGYRFQAKAKL 855
>gi|44662838 aminomethyltransferase [Homo sapiens]
Length = 403
Score = 70.5 bits (171), Expect = 7e-12
Identities = 85/371 (22%), Positives = 149/371 (40%), Gaps = 45/371 (12%)
Query: 553 HHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR-PPGSTVYTCML 611
+ D+ L R ++FD+S+ + ++G D K + L D++ P +
Sbjct: 61 YRDSHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFT 120
Query: 612 NHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQC 671
N GG DL V+ + EG Y ++ G W ++QD+ +
Sbjct: 121 NEAGGILDDLIVTNTS------------EGHLYVVSNAGC-----WEKDLALMQDKVREL 163
Query: 672 QLIDSSEDLGM-------ISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGHL-VR 723
Q + D+G+ +++QGP + +LQ + DL PF T ++ G R
Sbjct: 164 Q--NQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRK--LPFMTSAVMEVFGVSGCR 219
Query: 724 AMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLIN-AGYRAIDSLSIEKGYRHWHA 782
R + GE G E+ +P A V + A++ K+ + AG A DSL +E G +
Sbjct: 220 VTRCGYTGEDGVEISVPVAGAVHLATAIL----KNPEVKLAGLAARDSLRLEAGLCLYGN 275
Query: 783 DLRPDDSPLEAGLAFTC--KLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
D+ +P+E L++T + ++ + F G + + Q ++RR V E
Sbjct: 276 DIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPMRAHSP 335
Query: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
+ G +G V ++ K +A GY V ++ + G L +
Sbjct: 336 ILNMEGTKIGTVTSGCPSPSLKKNVAMGY--------VPCEYSRPGTMLLVEVRRKQQMA 387
Query: 901 AHLKSPFDPNN 911
K PF P N
Sbjct: 388 VVSKMPFVPTN 398
>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
sapiens]
Length = 486
Score = 60.5 bits (145), Expect = 7e-09
Identities = 95/429 (22%), Positives = 173/429 (40%), Gaps = 46/429 (10%)
Query: 57 QGPSRPLPSTANVVVIGGGSLGCQTLYHLAKL----GMSGAVLLERERLTS--GTTWHTA 110
Q S P ++VV++GGG LG Y L KL G +++ER+ S T
Sbjct: 54 QDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVG 113
Query: 111 GLLWQLR-PSDVEVELL-AHTRRVVSRELE--EETGLHTGWIQNGGLFIASNRQRLDEYK 166
G+ Q P ++++ L A R ++ L + L + +G L +AS + +
Sbjct: 114 GICQQFSLPENIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLASEKDAA-AME 172
Query: 167 RLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHD-GTMDPAGTCTTLARAAS 225
+ + + G + ++SP + + +P +N + + Y D G DP L R
Sbjct: 173 SNVKVQRQEGAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQ 232
Query: 226 ARGA-----QVIENCPVTGIRVWTDDFGV--RRVAGVET------QHGSIQTPCVVNCAG 272
+ G +V + + TDD V +R+ V ++ ++ V+N AG
Sbjct: 233 SLGVLFCQGEVTRFVSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAG 292
Query: 273 VWASAVGRMAGV-----------KVPLVAMHHAYVVTERIEGIQ-NMPNVRDHDASVYLR 320
W++ + +AGV K+P+ V +G P V D + + R
Sbjct: 293 AWSAQIAALAGVGEGPPGTLQGTKLPVEPRKRYVYVWHCPQGPGLETPLVADTSGAYFRR 352
Query: 321 LQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEGAIN-RVPVLEKTGIKST 379
+ +GG +P EE ++D + F + + RVP E ++S
Sbjct: 353 EGLGSNYLGG--RSPTEQEEPDP----ANLEVDHDFFQDKVWPHLALRVPAFETLKVQSA 406
Query: 380 VCGPESF-TPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEK-DM 437
G + T D ++G P + + GF+ G+ G G+ +A ++ GR + D+
Sbjct: 407 WAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGRFQTIDL 466
Query: 438 HGYDIRRFH 446
+ RF+
Sbjct: 467 SPFLFTRFY 475
>gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo
sapiens]
Length = 463
Score = 47.0 bits (110), Expect = 8e-05
Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 36/258 (13%)
Query: 51 GTSVVAQGPSRPL--------PSTANVVVIGGGSLGCQTLYHLAKLGMSGAV-LLERER- 100
G A G RPL S+ ++V++GGG +G + L S ++ +LE+E+
Sbjct: 25 GACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKD 84
Query: 101 LTSGTTWHTAGLLWQ---LRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIAS 157
L T H +G++ +P ++ +L ++ E ++ G+ + Q G L +A
Sbjct: 85 LAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLY-EYCQQKGI--SYKQCGKLIVAV 141
Query: 158 NRQRLDEYKRLMSLGKAYGVES-HVLSPAETKTLYP----LMNVDDLYGTLYVPHDGTMD 212
++ + + L G GV ++ + K P LM +D PH G +D
Sbjct: 142 EQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAID-------CPHTGIVD 194
Query: 213 PAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVE-------TQHGSIQTP 265
+ A+ G V+ N V GI + + R + G++ T+ I+
Sbjct: 195 YRQVALSFAQDFQEAGGSVLTNFEVKGIEM-AKESPSRSIDGMQYPIVIKNTKGEEIRCQ 253
Query: 266 CVVNCAGVWASAVGRMAG 283
VV CAG+++ + ++G
Sbjct: 254 YVVTCAGLYSDRISELSG 271
>gi|60499001 pipecolic acid oxidase [Homo sapiens]
Length = 390
Score = 38.9 bits (89), Expect = 0.022
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 68 NVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERL--TSGTTWHTAGLLWQLRPSDVEVEL 125
+ +VIG G GC T YHLAK +LLE+ L + G++ + ++ + D +
Sbjct: 9 DAIVIGAGIQGCFTAYHLAK-HRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRM 67
Query: 126 LAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPA 185
+ H + +LE E G T + GL + ++ E K + + VE LS
Sbjct: 68 M-HECYQIWAQLEHEAG--TQLHRQTGLLLLGMKEN-QELKTIQANLSRQRVEHQCLSSE 123
Query: 186 ETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTD 245
E K +P N+ G + G +D +G +A A + + +
Sbjct: 124 ELKQRFP--NIRLPRGEV-----GLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVV 176
Query: 246 DFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPL 288
+ + V+T S Q +V AG W + + R G+++PL
Sbjct: 177 EINPGLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPL 219
>gi|239753433 PREDICTED: hypothetical protein XP_002345652 [Homo
sapiens]
Length = 302
Score = 32.3 bits (72), Expect = 2.1
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 56 AQGP-SRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLW 114
A GP + P+P+ A +IGG L L LG+ V+L RERL+ T G L
Sbjct: 47 ATGPLAVPIPAPAPAALIGGSQKVLVILVGLLLLGID-IVILSRERLSKAPP--TPGALS 103
Query: 115 QLRPSDVEVELLAHTRRVVSRELEEETG-LHTGWIQNG 151
P + E T ++ L E+TG + T W Q G
Sbjct: 104 SPLPQLLLAEQEPGTPSSTAQGLWEKTGHVITSWPQAG 141
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 32.0 bits (71), Expect = 2.7
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 615 GGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSH-ITTVLQDQKSQCQL 673
GG S + V + P A GD + L +GG Q S + VL++ + ++
Sbjct: 264 GGKTSGVVVRTIVPGGLADRDGRLQTGD-HILKIGGTNVQGMTSEQVAQVLRNCGNSVRM 322
Query: 674 IDSSEDLGMISIQGPASRAI---LQEVLDADLSNEAFPFSTH--KLLRAAGHLVRAMRLS 728
+ + + G IS+ PA A+ L V +++ F T+ +L+R G +++ +
Sbjct: 323 LVARDPAGDISVTPPAPAALPVALPTVASKGPGSDSSLFETYNVELVRKDG---QSLGIR 379
Query: 729 FVGELGWELHIPKASCVPVYRAVMAAGAKHG---LINAGYRAIDSLSIEKGYRH 779
VG +G H +AS + V + + A H +N A+D ++I+ H
Sbjct: 380 IVGYVGTS-HTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANH 432
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 32.0 bits (71), Expect = 2.7
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Query: 81 TLYHLAKLGMSGA--VLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHT-----RRVV 133
TL+HL L V++ RE+L H A L LRP DV+ E L T VV
Sbjct: 730 TLHHLRMLDFRSDQFVIIRREKLIQD---HMAKLQLNLRPVDVDPECLRWTPVIVSNSVV 786
Query: 134 SRELEEE 140
S E EEE
Sbjct: 787 SEEEEEE 793
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 32.0 bits (71), Expect = 2.7
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Query: 81 TLYHLAKLGMSGA--VLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHT-----RRVV 133
TL+HL L V++ RE+L H A L LRP DV+ E L T VV
Sbjct: 730 TLHHLRMLDFRSDQFVIIRREKLIQD---HMAKLQLNLRPVDVDPECLRWTPVIVSNSVV 786
Query: 134 SRELEEE 140
S E EEE
Sbjct: 787 SEEEEEE 793
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 32.0 bits (71), Expect = 2.7
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Query: 81 TLYHLAKLGMSGA--VLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHT-----RRVV 133
TL+HL L V++ RE+L H A L LRP DV+ E L T VV
Sbjct: 730 TLHHLRMLDFRSDQFVIIRREKLIQD---HMAKLQLNLRPVDVDPECLRWTPVIVSNSVV 786
Query: 134 SRELEEE 140
S E EEE
Sbjct: 787 SEEEEEE 793
>gi|8923900 cytidine monophospho-N-acetylneuraminic acid synthetase
[Homo sapiens]
Length = 434
Score = 31.2 bits (69), Expect = 4.6
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 25/106 (23%)
Query: 1 MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
M S+ + + ++PR P+RG P QR + GQG +G
Sbjct: 1 MDSVEKGAATSVSNPRGRPSRGRPP---------------KLQRNSRGGQG-----RGVE 40
Query: 61 RPLPSTANVVVIGGGSLG--CQTLYHLAKLGMSGAVLLERERLTSG 104
+P P A +++ GGS G + + HLA + + G VL R L SG
Sbjct: 41 KP-PHLAALILARGGSKGIPLKNIKHLAGVPLIGWVL--RAALDSG 83
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 31.2 bits (69), Expect = 4.6
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 14 HPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIG 73
HP P + GP ++ P ++ ++PY + QG + PS+P+ + ++ V
Sbjct: 686 HP---PLQSAGPSEQVNSKAPLSKSALPYS-SFSSDQGLGESSAAPSQPITAVKDMPVRS 741
Query: 74 GGSL 77
GG L
Sbjct: 742 GGLL 745
>gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens]
Length = 630
Score = 30.8 bits (68), Expect = 6.1
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)
Query: 46 LKEGQGTSVVAQGPSRPLPSTANVV---VIGGGSLGCQTLYHLAKLGMSGAVLLERERLT 102
L+ +G + Q P RPLP A ++ V G G L TL L L E L+
Sbjct: 399 LEVNKGHEMSPQAPRRPLPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELS 458
Query: 103 SGTTWHTAGLLWQLRPSDVE 122
S +W +RP D++
Sbjct: 459 S----VPPSSIWAVRPQDLD 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,568,574
Number of Sequences: 37866
Number of extensions: 1797608
Number of successful extensions: 3565
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3528
Number of HSP's gapped (non-prelim): 21
length of query: 918
length of database: 18,247,518
effective HSP length: 111
effective length of query: 807
effective length of database: 14,044,392
effective search space: 11333824344
effective search space used: 11333824344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.