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Search of human proteins with 212276088
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|212276088 leucine rich repeat (in FLII) interacting protein
1 isoform 2 [Homo sapiens]
(394 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|212276088 leucine rich repeat (in FLII) interacting protein 1... 749 0.0
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 541 e-154
gi|212276104 leucine rich repeat (in FLII) interacting protein 1... 463 e-130
gi|212276070 leucine rich repeat (in FLII) interacting protein 1... 447 e-125
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 433 e-121
gi|8923224 leucine rich repeat (in FLII) interacting protein 2 i... 422 e-118
gi|197276647 leucine rich repeat (in FLII) interacting protein 2... 410 e-115
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 296 2e-80
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 67 4e-11
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 65 1e-10
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 65 1e-10
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 65 1e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 64 2e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 64 2e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 64 2e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 64 2e-10
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 64 2e-10
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 64 2e-10
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 64 2e-10
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 64 2e-10
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 64 3e-10
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 64 3e-10
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 64 3e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 63 5e-10
gi|156104908 myosin heavy chain 6 [Homo sapiens] 62 7e-10
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 62 9e-10
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 62 9e-10
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 62 9e-10
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l... 62 1e-09
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 62 1e-09
>gi|212276088 leucine rich repeat (in FLII) interacting protein 1
isoform 2 [Homo sapiens]
Length = 394
Score = 749 bits (1934), Expect = 0.0
Identities = 394/394 (100%), Positives = 394/394 (100%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV
Sbjct: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE
Sbjct: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL
Sbjct: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN
Sbjct: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR
Sbjct: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Query: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ
Sbjct: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 541 bits (1394), Expect = e-154
Identities = 309/434 (71%), Positives = 323/434 (74%), Gaps = 86/434 (19%)
Query: 47 RQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK- 105
R VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK
Sbjct: 207 RASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKE 266
Query: 106 -----------------------DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 142
DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM
Sbjct: 267 LNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 326
Query: 143 LLELE-----------------------------------------EQLAESRRQYEEKN 161
LLELE E++ E RQ ++K
Sbjct: 327 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQKQ 386
Query: 162 KE---------------------FEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILN 200
ER+K ++ + +++E + +E L+KHGIILN
Sbjct: 387 ASSIREISDLQETIEWKDKKIGALERQKEFFDSVRSERDDLREEVVMLKEELKKHGIILN 446
Query: 201 SEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKK 260
SEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKK
Sbjct: 447 SEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKK 506
Query: 261 LKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITAL 320
LKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITAL
Sbjct: 507 LKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITAL 566
Query: 321 EQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRL 380
EQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRL
Sbjct: 567 EQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRL 626
Query: 381 EKMKANRSALLSQQ 394
EKMKANRSALLSQQ
Sbjct: 627 EKMKANRSALLSQQ 640
Score = 59.3 bits (142), Expect = 6e-09
Identities = 34/48 (70%), Positives = 40/48 (83%), Gaps = 1/48 (2%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEK 58
E D L+ A++ AEARLAAKRAARAEAREIRMKELERQQKE+ + +K
Sbjct: 22 EDDALNQIARE-AEARLAAKRAARAEAREIRMKELERQQKEIYQVQKK 68
>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
isoform 5 [Homo sapiens]
Length = 752
Score = 463 bits (1192), Expect = e-130
Identities = 256/345 (74%), Positives = 276/345 (80%), Gaps = 12/345 (3%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV
Sbjct: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE
Sbjct: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL
Sbjct: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
R +E ++ + +R+ + + + +D +++ D+ V +
Sbjct: 241 G---------RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTE 291
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIE 345
Q S E+ V +SQ+ S EN ++E
Sbjct: 292 DQKSSEDTAPFLGTLAGATYEEQV---QSQILESSSLPENTVQVE 333
Score = 33.5 bits (75), Expect = 0.34
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Query: 17 PEAQKLAEARLAAKRAARAEAREIRMKELERQQKEV-EERPEKDFTEKGSRNMPGLSAAT 75
P+ + + K EA E KE+ EV + E++ E G R+ +
Sbjct: 405 PQELETSTGHSLEKEFTNQEAAE--PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 462
Query: 76 LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS------NAQLDNEK 129
S GT ++DT+ ++K+ E ++ +A+ S N + N+K
Sbjct: 463 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 522
Query: 130 TNFMYQVDTLKDMLLELEEQLAE-SRRQYEEKNKEFERE 167
V+TLKD+ EL Q + S + EE+ K +R+
Sbjct: 523 KKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 561
>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
isoform 4 [Homo sapiens]
Length = 784
Score = 447 bits (1149), Expect = e-125
Identities = 256/377 (67%), Positives = 276/377 (73%), Gaps = 44/377 (11%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 89 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 148
GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE
Sbjct: 121 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
Query: 149 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 208
QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE
Sbjct: 181 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 240
Query: 209 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEER 268
TSDTLNNVGYQGPTKMTKEELNALKSTGDGTL R +E ++ + +R
Sbjct: 241 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG---------RASEVEVKNEIVANVGKR 291
Query: 269 QKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLE 328
+ + + + +D +++ D+ V + Q S E+ V +
Sbjct: 292 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQV---Q 348
Query: 329 SQVSRYKSAAENAEKIE 345
SQ+ S EN ++E
Sbjct: 349 SQILESSSLPENTVQVE 365
Score = 33.5 bits (75), Expect = 0.34
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Query: 17 PEAQKLAEARLAAKRAARAEAREIRMKELERQQKEV-EERPEKDFTEKGSRNMPGLSAAT 75
P+ + + K EA E KE+ EV + E++ E G R+ +
Sbjct: 437 PQELETSTGHSLEKEFTNQEAAE--PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 494
Query: 76 LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS------NAQLDNEK 129
S GT ++DT+ ++K+ E ++ +A+ S N + N+K
Sbjct: 495 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 554
Query: 130 TNFMYQVDTLKDMLLELEEQLAE-SRRQYEEKNKEFERE 167
V+TLKD+ EL Q + S + EE+ K +R+
Sbjct: 555 KKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 593
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 433 bits (1114), Expect = e-121
Identities = 256/401 (63%), Positives = 276/401 (68%), Gaps = 68/401 (16%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 89 GDTSISIDTEASIREIK------------------------DSLAEVEEKYKKAMVSNAQ 124
GDTSISIDTEASIREIK DSLAEVEEKYKKAMVSNAQ
Sbjct: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
Query: 125 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 184
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
Query: 185 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRL 244
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL
Sbjct: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG--- 297
Query: 245 KKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQIS 304
R +E ++ + +R+ + + + +D +++ D+ V + Q S
Sbjct: 298 ------RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKS 351
Query: 305 DLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIE 345
E+ V +SQ+ S EN ++E
Sbjct: 352 SEDTAPFLGTLAGATYEEQV---QSQILESSSLPENTVQVE 389
Score = 33.5 bits (75), Expect = 0.34
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Query: 17 PEAQKLAEARLAAKRAARAEAREIRMKELERQQKEV-EERPEKDFTEKGSRNMPGLSAAT 75
P+ + + K EA E KE+ EV + E++ E G R+ +
Sbjct: 461 PQELETSTGHSLEKEFTNQEAAE--PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 518
Query: 76 LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS------NAQLDNEK 129
S GT ++DT+ ++K+ E ++ +A+ S N + N+K
Sbjct: 519 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 578
Query: 130 TNFMYQVDTLKDMLLELEEQLAE-SRRQYEEKNKEFERE 167
V+TLKD+ EL Q + S + EE+ K +R+
Sbjct: 579 KKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 617
>gi|8923224 leucine rich repeat (in FLII) interacting protein 2
isoform 2 [Homo sapiens]
Length = 400
Score = 422 bits (1084), Expect = e-118
Identities = 228/387 (58%), Positives = 297/387 (76%), Gaps = 5/387 (1%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE++E+ +K + E +R
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPS 76
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNE 128
SA+ L G SSRRGSGDTS ID + S+ E+++SL+EVEEKYKKAMVSNAQLDNE
Sbjct: 77 SRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNE 136
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQR 188
K N +YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH S+LQ + E+KE L+QR
Sbjct: 137 KNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQR 196
Query: 189 EEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLV 248
+E++EKHG+++ + NG+ S + T +++E L+S G+G LD+RL+KL
Sbjct: 197 DELIEKHGLVIIPDGTPNGDVS---HEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLA 253
Query: 249 DERECLLEQIKKLKGQL-EERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLK 307
E+E LL QI+KLK QL EERQK + D + L+NG+D+ +++QRDANRQIS+ K
Sbjct: 254 GEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYK 313
Query: 308 FKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTE 367
FKL+K+EQ+IT LEQ++ RLE QV RYK+AAENAEK+EDELKAEKRKLQRELR+ALDK E
Sbjct: 314 FKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEKVEDELKAEKRKLQRELRTALDKIE 373
Query: 368 ELEVSNGHLVKRLEKMKANRSALLSQQ 394
E+E++N HL KRLEKMKANR+ALL+QQ
Sbjct: 374 EMEMTNSHLAKRLEKMKANRTALLAQQ 400
>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
isoform 3 [Homo sapiens]
Length = 424
Score = 410 bits (1055), Expect = e-115
Identities = 229/411 (55%), Positives = 298/411 (72%), Gaps = 29/411 (7%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE++E+ +K + E +R
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPS 76
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDTEASI------------------------REI 104
SA+ L G SSRRGSGDTS ID + S+ +E+
Sbjct: 77 SRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKEL 136
Query: 105 KDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEF 164
K+SL+EVEEKYKKAMVSNAQLDNEK N +YQVDTLKD++ E EEQ+AE R+ EEK+KE
Sbjct: 137 KESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKEL 196
Query: 165 EREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKM 224
ER+KH S+LQ + E+KE L+QR+E++EKHG+++ + NG+ S + T +
Sbjct: 197 ERQKHMCSVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVS---HEPVAGAITVV 253
Query: 225 TKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEE-RQKIGKLDNLRSEDDV 283
++E L+S G+G LD+RL+KL E+E LL QI+KLK QLEE RQK + D +
Sbjct: 254 SQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAG 313
Query: 284 LENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEK 343
L+NG+D+ +++QRDANRQIS+ KFKL+K+EQ+IT LEQ++ RLE QV RYK+AAENAEK
Sbjct: 314 LQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEK 373
Query: 344 IEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
+EDELKAEKRKLQRELR+ALDK EE+E++N HL KRLEKMKANR+ALL+QQ
Sbjct: 374 VEDELKAEKRKLQRELRTALDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ 424
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 296 bits (758), Expect = 2e-80
Identities = 192/450 (42%), Positives = 262/450 (58%), Gaps = 97/450 (21%)
Query: 35 AEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS 94
+E +I + +L ++ +++ +++T SRN SA+ L G SSRRGSGDTS
Sbjct: 279 SEVDDISIPDLSSLDEKSDKQYAENYTRPSSRN----SASATTPLSGNSSRRGSGDTSSL 334
Query: 95 IDTEASI------------------------REIKDSLAEVEEKYKKAMVSNAQLDNEKT 130
ID + S+ +E+K+SL+EVEEKYKKAMVSNAQLDNEK
Sbjct: 335 IDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKN 394
Query: 131 NFMYQVDTLKDMLLELEEQ-------------------------------LAESRRQYEE 159
N +YQVDTLKD++ E EEQ L E RQ +E
Sbjct: 395 NLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDE 454
Query: 160 KNKEFEREKHAHSILQFQFAEVKEAL-----------KQRE---------EML------- 192
+E +R + + + +++E L KQ+E +ML
Sbjct: 455 LIEEKQRMQQKIDTMTKEVFDLQETLLWKDKKIGALEKQKEYIACLRNERDMLREELADL 514
Query: 193 -------EKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLK 245
EKHG+++ + NG+ S + T +++E L+S G+G LD+RL+
Sbjct: 515 QETVKTGEKHGLVIIPDGTPNGDVS---HEPVAGAITVVSQEAAQVLESAGEGPLDVRLR 571
Query: 246 KLVDERECLLEQIKKLKGQLEE-RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQIS 304
KL E+E LL QI+KLK QLEE RQK + D + L+NG+D+ +++QRDANRQIS
Sbjct: 572 KLAGEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQIS 631
Query: 305 DLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALD 364
+ KFKL+K+EQ+IT LEQ++ RLE QV RYK+AAENAEK+EDELKAEKRKLQRELR+ALD
Sbjct: 632 EYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEKVEDELKAEKRKLQRELRTALD 691
Query: 365 KTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
K EE+E++N HL KRLEKMKANR+ALL+QQ
Sbjct: 692 KIEEMEMTNSHLAKRLEKMKANRTALLAQQ 721
Score = 56.6 bits (135), Expect = 4e-08
Identities = 39/94 (41%), Positives = 51/94 (54%), Gaps = 17/94 (18%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE----------------V 52
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE +
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKEYSLHSFDRKWGQIQKWL 76
Query: 53 EERPEKDFTEKGSRNMPGLSAATLASLGGTSSRR 86
E+ ++ + S + P L S+ S R
Sbjct: 77 EDSERARYSHRSSHHRPYLGVEDALSIRSVGSHR 110
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 66.6 bits (161), Expect = 4e-11
Identities = 66/280 (23%), Positives = 128/280 (45%), Gaps = 26/280 (9%)
Query: 117 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 176
K ++ +A+ + E N + + K+ L + E + R++ EEK +EK+ LQ
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAK----RKELEEKMVTLMQEKND---LQL 893
Query: 177 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTG 236
Q ++L EE ++ ++ ++I + + +EE+NA +
Sbjct: 894 QVQAEADSLADAEERCDQ---LIKTKIQLEAKIKEVTERAE-------DEEEINAELTAK 943
Query: 237 DGTLD---IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVM 293
L+ LKK +D+ E L +++K K E + K + + D+ + T
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK-NLTEEMAGLDETIAKLTK-EKK 1001
Query: 294 DLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKR 353
LQ + + DL+ + E ++ L + I+LE QV + + E +KI +L+ KR
Sbjct: 1002 ALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKR 1057
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KL+ +L+ A + T ++E L ++L+K + S L S+
Sbjct: 1058 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSK 1097
Score = 59.3 bits (142), Expect = 6e-09
Identities = 75/424 (17%), Positives = 184/424 (43%), Gaps = 61/424 (14%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+T +++D L ++ + R+ +RA R ++++ + E +++ +
Sbjct: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEK 1083
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
+K M GL + + ++ + + I+E++ + E+EE+ +
Sbjct: 1084 LKKKEFEMSGLQSKI------------EDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLEL--------------EEQLAESRRQYEEKNKEFE- 165
S A+ + ++++ +++ + + L E E + + RR EE + E
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 166 -----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNV--GY 218
R+KHA S+ + E + L++ ++ LEK + EI +T++
Sbjct: 1192 TAATLRKKHADSVA--ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 1249
Query: 219 QGPTKMTKEELNALKSTGD----------------GTLDIRLKKLVDERECLLEQIKKLK 262
+ + +++L+ +K+ + T + +DE++ L+ Q+ +
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLS--R 1307
Query: 263 GQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITA-LE 321
G+ Q+I +L + E+++ H + ++R DL + + EQE A L+
Sbjct: 1308 GKQAFTQQIEELKR-QLEEEIKAKSALAHAL----QSSRHDCDLLREQYEEEQEAKAELQ 1362
Query: 322 QNVIRLESQVSRYKSAAE-NAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRL 380
+ + + S+V+++++ E +A + +EL+ K+KL + L+ A + E + L K
Sbjct: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422
Query: 381 EKMK 384
++++
Sbjct: 1423 QRLQ 1426
Score = 58.5 bits (140), Expect = 1e-08
Identities = 76/342 (22%), Positives = 147/342 (42%), Gaps = 40/342 (11%)
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI------DTEASIREIKDSLAEVEEK 114
TEK NM T L T ++R + + D + ++ DSLA+ EE+
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 115 YKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 174
+ + + QL+ + + +V + E+ +L +R+ E++ E +++ +
Sbjct: 909 CDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 175 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEE--LNAL 232
+ + K A + + + L + L+ IA + L Q + EE +N L
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 233 KSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHV 292
I+L++ VD+ E LEQ KK++ LE ++ L + + + T
Sbjct: 1025 TKA-----KIKLEQQVDDLEGSLEQEKKIRMDLERAKR-----KLEGDLKLAQEST---- 1070
Query: 293 MDLQRDANRQISDLKFKLAKSEQEITALEQNV-----IRLESQVSRYKSAAENAEKIEDE 347
MD++ D + L KL K E E++ L+ + + ++ Q + K E++E+E
Sbjct: 1071 MDIENDKQQ----LDEKLKKKEFEMSGLQSKIEDEQALGMQLQ-KKIKELQARIEELEEE 1125
Query: 348 LKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
++AE+ + + D + ELE + +RLE+ SA
Sbjct: 1126 IEAERASRAKAEKQRSDLSRELE----EISERLEEAGGATSA 1163
Score = 54.3 bits (129), Expect = 2e-07
Identities = 59/316 (18%), Positives = 139/316 (43%), Gaps = 25/316 (7%)
Query: 83 SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 142
+ R+ GD ++ + S +I++ +++EK KK + E + +++ + +
Sbjct: 1055 AKRKLEGDLKLA---QESTMDIENDKQQLDEKLKKK-------EFEMSGLQSKIEDEQAL 1104
Query: 143 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSE 202
++L++++ E + + EE +E E E+ + + + Q +++ L++ E LE+ G +++
Sbjct: 1105 GMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1164
Query: 203 IATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQI---K 259
I N + + + +L + T KK D L EQI +
Sbjct: 1165 IEMNKKREAEFQKM---------RRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1215
Query: 260 KLKGQLEERQKIGKL--DNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEI 317
++K +LE+ + K+ D+L S + + ++ + R Q+S++K K + ++ I
Sbjct: 1216 RVKQKLEKEKSEMKMEIDDLASNMETVSKAKG-NLEKMCRALEDQLSEIKTKEEEQQRLI 1274
Query: 318 TALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLV 377
L RL+++ Y + + + +L K+ +++ + EE + L
Sbjct: 1275 NDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALA 1334
Query: 378 KRLEKMKANRSALLSQ 393
L+ + + L Q
Sbjct: 1335 HALQSSRHDCDLLREQ 1350
Score = 49.3 bits (116), Expect = 6e-06
Identities = 77/367 (20%), Positives = 165/367 (44%), Gaps = 37/367 (10%)
Query: 41 RMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 100
R+ ELE+ +K+VE+ EK + + A+L G R + + +
Sbjct: 1526 RIHELEKIKKQVEQ--EKSELQAALEE----AEASLEHEEGKILRIQLELNQVKSEVDRK 1579
Query: 101 IREIKDSLAEVEEKYKKAMVS-NAQLDNEKTNFMYQVDTLKDM---LLELEEQLAESRRQ 156
I E + + +++ + + + S + LD E + + K M L E+E QL + R
Sbjct: 1580 IAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1639
Query: 157 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREE------MLEKHGIILNSEIATNGETS 210
E + + ++ +IL+ + +AL+ +E+ M+E+ +L +EI E
Sbjct: 1640 AAEALRNY---RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIE---ELR 1693
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE---- 266
TL + K+ ++EL L + L++ ++ L I +++G++E
Sbjct: 1694 ATLEQT--ERSRKIAEQELLDASERVQ-LLHTQNTSLINTKKKLETDISQIQGEMEDIIQ 1750
Query: 267 ------ERQKIGKLDN-LRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQ-EIT 318
E+ K D + +E+ E T H+ ++++ + + DL+ +L ++EQ +
Sbjct: 1751 EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALK 1810
Query: 319 ALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVK 378
++ + +LE++V + E+ +K E RK +R+++ +TEE + L
Sbjct: 1811 GGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQD 1870
Query: 379 RLEKMKA 385
++K++A
Sbjct: 1871 LVDKLQA 1877
Score = 48.9 bits (115), Expect = 8e-06
Identities = 90/445 (20%), Positives = 165/445 (37%), Gaps = 106/445 (23%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTS 83
E + A+RA+RA+A + R +L R+ +E+ ER E E G +
Sbjct: 1123 EEEIEAERASRAKAEKQR-SDLSRELEEISERLE----EAGGATSAQIEMNKKREAEFQK 1177
Query: 84 SRRGSGDTSISIDTEASIREIK--DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD---- 137
RR + ++ + A+ K DS+AE+ E+ +L+ EK+ ++D
Sbjct: 1178 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1237
Query: 138 ----------TLKDMLLELEEQLAESRRQYEEKNK-----------------EFEREKHA 170
L+ M LE+QL+E + + EE+ + E+ R+
Sbjct: 1238 NMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE 1297
Query: 171 HSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVG---------YQGP 221
L Q + K+A Q+ E L++ L EI + L + Y+
Sbjct: 1298 KDTLVSQLSRGKQAFTQQIEELKRQ---LEEEIKAKSALAHALQSSRHDCDLLREQYEEE 1354
Query: 222 TKMTKEELNALKSTGDGTLDIRLKKLVD---ERECLLEQIKKLKGQLEERQKI-----GK 273
+ E A+ R K D E L E KKL +L++ ++ K
Sbjct: 1355 QEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAK 1414
Query: 274 LDNLRSEDDVLENGTDMHVMDL-------------QRDANRQISDLKFKLAKSEQEITAL 320
+L L+N + ++D+ QR+ ++ +++ K K ++ E+ A
Sbjct: 1415 CASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS 1474
Query: 321 EQNVIRLESQVSRYKSAAENA-----------------------------------EKIE 345
++ L +++ + K+A E + EKI+
Sbjct: 1475 QKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1534
Query: 346 DELKAEKRKLQRELRSALDKTEELE 370
+++ EK +LQ L A E E
Sbjct: 1535 KQVEQEKSELQAALEEAEASLEHEE 1559
Score = 48.5 bits (114), Expect = 1e-05
Identities = 88/429 (20%), Positives = 182/429 (42%), Gaps = 92/429 (21%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPG 70
EID L+ + +++A+ ++ RA E ++ E++ +++E ++R D T + +R
Sbjct: 1231 EIDDLASNMETVSKAKGNLEKMCRA--LEDQLSEIKTKEEE-QQRLINDLTAQRAR---- 1283
Query: 71 LSAATLASLGGTSSRR-GSGDT---SISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLD 126
L + G SR+ DT +S +A ++I++ ++EE+ K + + L
Sbjct: 1284 -----LQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIK----AKSALA 1334
Query: 127 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE--REKHAHSILQF--QFAEVK 182
+ + + D L++ E +E AE +R + N E R K+ +Q + E K
Sbjct: 1335 HALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAK 1394
Query: 183 EALKQREEMLEKHGIILNSEIATNGETSDTLNNV-------------------------- 216
+ L QR + E+H +N++ A+ +T L N
Sbjct: 1395 KKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454
Query: 217 ------------------GYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQI 258
Q ++ EL +K+ + +LD +L+ L E + L ++I
Sbjct: 1455 KILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD-QLETLKRENKNLQQEI 1513
Query: 259 KKLKGQLEERQK-IGKLDNLRSEDD--------VLENGT------DMHVMDLQRDANRQI 303
L Q+ E K I +L+ ++ + + LE + ++ +Q + N+
Sbjct: 1514 SDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVK 1573
Query: 304 SDLKFKLAKSEQEITALEQNVIR--------LESQVSRYKSAAENAEKIEDELKAEKRKL 355
S++ K+A+ ++EI +++N IR L++++ A +K+E +L + +L
Sbjct: 1574 SEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQL 1633
Query: 356 QRELRSALD 364
R A +
Sbjct: 1634 NHANRMAAE 1642
Score = 31.6 bits (70), Expect = 1.3
Identities = 31/172 (18%), Positives = 76/172 (44%), Gaps = 11/172 (6%)
Query: 22 LAEARLAAKRAARAEAREIRMKELERQQKEVE---ERPEKDFTEKGSRNMPGLSAATLAS 78
+ EAR A ++A +A M E +++++ ER +K+ + L A +
Sbjct: 1749 IQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1808
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
L G G I EA +RE++ + +++ +A+ + + + YQ +
Sbjct: 1809 LKG-------GKKQIQ-KLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE 1860
Query: 139 LKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREE 190
+ +L L++ + + + + + ++ E + ++ +F ++ L++ EE
Sbjct: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEE 1912
Score = 31.2 bits (69), Expect = 1.7
Identities = 69/316 (21%), Positives = 130/316 (41%), Gaps = 46/316 (14%)
Query: 13 DCLSPEAQKLAEARLAAKRA--ARAEAREIR--MKELERQQKEVEERPEKDFTEKGSRNM 68
D L + + + +RA +AE E+R +++ ER +K + E+ D +E+
Sbjct: 1663 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRK-IAEQELLDASERVQ--- 1718
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNE 128
L SL T + + + I + E I+E +++ EEK KKA+ A + E
Sbjct: 1719 --LLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNA----EEKAKKAITDAAMMAEE 1772
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQR 188
LK +EQ + + +KN E + H + + + +K KQ
Sbjct: 1773 ----------LK------KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1816
Query: 189 EEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDI-RLKKL 247
++ LE L E+ E+ N +G K ++ T + +I RL+ L
Sbjct: 1817 QK-LEARVRELEGEV----ESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDL 1871
Query: 248 VDERECLLEQIKKLKGQLEERQKI--GKLDNLRSEDDVLENGTDMHVMDLQRDANRQISD 305
VD+ + ++ K+ + EE+ + K ++ E + E D+ A Q++
Sbjct: 1872 VDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADI--------AESQVNK 1923
Query: 306 LKFKLAKSEQEITALE 321
L+ K + +I + E
Sbjct: 1924 LRVKSREVHTKIISEE 1939
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 64.7 bits (156), Expect = 1e-10
Identities = 87/407 (21%), Positives = 175/407 (42%), Gaps = 63/407 (15%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPG 70
E D LS E Q L + E + LE +K + + TE+G++++PG
Sbjct: 1748 EKDSLSEEVQDLKH---------QIEGNVSKQANLEATEKHDNQT---NVTEEGTQSIPG 1795
Query: 71 -------LSAATLASLGGTSSRRGSGDTSISIDTEA---------SIREIKDSLAEVEEK 114
LS +T + + S + ++S D + I ++K+ +A +EE+
Sbjct: 1796 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE 1855
Query: 115 YKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 174
+K + L+NEK + Q+ T L L+E++ + ++ +E R
Sbjct: 1856 KQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSR-------- 1907
Query: 175 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNV-GYQGPTKMTKEELNALK 233
++KE ++ ++ LE+ ++N NG + +V Q ++ + E+
Sbjct: 1908 ---VTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMK--- 1959
Query: 234 STGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVM 293
LKK V E E +Q+ K K ++E + L+ ++ E G H
Sbjct: 1960 ---------NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQK--EPGNKSHAK 2008
Query: 294 DLQ---RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
+LQ ++ +++ L+ + +++I+ALE+ V LE + + E ++ +
Sbjct: 2009 ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2068
Query: 351 EKRKLQRELRS---ALDKTE-ELEVSNGHLVKRLEKMKANRSALLSQ 393
++K Q EL S LD T+ E +K +++++N+ ++ SQ
Sbjct: 2069 HRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ 2115
Score = 54.7 bits (130), Expect = 1e-07
Identities = 90/431 (20%), Positives = 182/431 (42%), Gaps = 74/431 (17%)
Query: 34 RAEAREIRMKELERQQK------EVEERPEKDFTEKGSRNMPGLSAATL------ASLGG 81
+A+ +EI +++E + K E+ ++ E+ F + N GL +L A +
Sbjct: 1308 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHA 1367
Query: 82 TSSRRGSGDTSISIDTEASIREIKDSLAEVEE---------KYKKAMVSN--AQLDNEKT 130
S ++ + + I +RE++ L E+++ Y +S A L +T
Sbjct: 1368 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT 1427
Query: 131 NFMYQVDTLKDMLLELEEQ--------------LAESRRQYEEKNKEFEREKHAHSILQF 176
+ Q D +K + +LE Q L E +++ EE +E ++ LQ
Sbjct: 1428 EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1487
Query: 177 QFAEVKEALKQREEMLEKHGII-------------LNSEIATNGETSDT-------LNNV 216
KEALK+ + + E+ + + S+++ + DT L
Sbjct: 1488 ALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1547
Query: 217 GYQGPTKMTKEEL-NALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQ--LEERQKIGK 273
+ T+M + L N S+ +L + L+ L +++E L+++I+ LK E + K
Sbjct: 1548 RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEK 1607
Query: 274 LDNLRSEDDVL----ENGTD-----MHVMDLQRDANRQI-SDLKFKLAKSEQEITALEQN 323
L+ E ++L EN ++ HV++ R +++ L+ A ++ L++
Sbjct: 1608 HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1667
Query: 324 VIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEE----LEVSNGHLVKR 379
+E + + A++ ++ EL+ E +L+ E+ A D +E L SN + +
Sbjct: 1668 EQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEE 1727
Query: 380 LEKMKANRSAL 390
LE++K L
Sbjct: 1728 LERVKMEYETL 1738
Score = 54.3 bits (129), Expect = 2e-07
Identities = 67/316 (21%), Positives = 142/316 (44%), Gaps = 32/316 (10%)
Query: 93 ISIDTEASIREIKDSLAEVEEKYKKAMVSNAQL-----DNEKTNFMYQVDTLKDMLLELE 147
+ +++ + K++LA+ E KKA A D + D LK + EL+
Sbjct: 2048 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLK-LKKELQ 2106
Query: 148 EQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEI---A 204
+ Q ++K+++ ER + + AE K LK+++ M EK + ++
Sbjct: 2107 SNKESVKSQMKQKDEDLER--------RLEQAEEKH-LKEKKNMQEKLDALRREKVHLEE 2157
Query: 205 TNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQ 264
T GE TLN + + +E L++ T + L D+R+ ++++ KK + +
Sbjct: 2158 TIGEIQVTLNKKDKE--VQQLQENLDSTV-TQLAAFTKSMSSLQDDRDRVIDEAKKWERK 2214
Query: 265 LEERQKIGKLDNLRSEDD---VLENGT---DMHVMDLQRDANRQISDLKFKLAKSEQEIT 318
+ + K + +R ++D VL++ +H+ +L+ + +R D + +K++ E+
Sbjct: 2215 FSDAIQ-SKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQ 2273
Query: 319 ALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVK 378
++ L+ + S E + + E KL+ EL+S D+ +L S ++
Sbjct: 2274 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNS----LE 2329
Query: 379 RLEKMKANRSALLSQQ 394
+ ++ K N ++ QQ
Sbjct: 2330 KCKEQKGNLEGIIRQQ 2345
Score = 51.6 bits (122), Expect = 1e-06
Identities = 78/385 (20%), Positives = 161/385 (41%), Gaps = 46/385 (11%)
Query: 36 EAREIRMKELERQQK--EVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSI 93
E +I + LE ++ E + + E +K + G + L+ L T S +
Sbjct: 2248 EELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNEL 2307
Query: 94 SIDTEASIREIKDSLAEVEEKYKKA---------MVSNAQLDNEKTNFMY-QVDTLKDML 143
+ E+ ++ +KD L ++ +K ++ + D + + F Y Q++T
Sbjct: 2308 A-KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQAS 2366
Query: 144 LELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA----LKQREEML---EKHG 196
EL +L E E+K K +Q AE+++ +K+ E +L E+
Sbjct: 2367 RELTSRLHEEINMKEQKIISLLSGKE--EAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2424
Query: 197 IILNSE----IATNGETSDTLN-----NVGYQGPTKMTKEELNALKSTGDGT------LD 241
I+L E + + +TL N+ + + +++L++ D L+
Sbjct: 2425 IVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE 2484
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEE--RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDA 299
R ++ E++ L+++ +L+E R +D+L SE+ L+ + DL +
Sbjct: 2485 ERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2544
Query: 300 NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQREL 359
+ S K L Q+ LE +LE ++ + A E+ + + L+ EK+ L +E+
Sbjct: 2545 TIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEI 2604
Query: 360 RSALDKTEELEVSNGHLVKRLEKMK 384
E L+VS L +++ ++
Sbjct: 2605 -------ESLKVSISQLTRQVTALQ 2622
Score = 50.8 bits (120), Expect = 2e-06
Identities = 79/415 (19%), Positives = 160/415 (38%), Gaps = 67/415 (16%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAA 74
LS +K E + + R + +I+ + +Q E + + ++ T + +
Sbjct: 2324 LSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQK 2383
Query: 75 TLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMY 134
++ L G + + I+E+++ L++ EE+ N + ++ M
Sbjct: 2384 IISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLME 2443
Query: 135 QVDTLKDMLLELEEQLAESRRQYEEKNKEFER---------EKHAHSILQF-----QFAE 180
+ T+K ++ + QL + + +R E+H IL+ + A
Sbjct: 2444 TLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAA 2503
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
LK+ L H LNSE N +E+LN + + D
Sbjct: 2504 ENNKLKEEIRGLRSHMDDLNSE------------NAKLDAELIQYREDLNQVITIKDSQQ 2551
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
L+ + + + L + KL+ +L+E ++ ++LR + L+ + ++D +
Sbjct: 2552 KQLLEVQLQQNKELENKYAKLEEKLKESEEAN--EDLRRSFNALQ--------EEKQDLS 2601
Query: 301 RQISDLKFKLAKSEQEITAL----------------EQNVIRL---------------ES 329
++I LK +++ +++TAL E+ V RL E
Sbjct: 2602 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2661
Query: 330 QVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMK 384
V K AA+ +IED+LK E + L + ++TE E L + L +M+
Sbjct: 2662 LVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEME 2716
Score = 49.7 bits (117), Expect = 5e-06
Identities = 81/399 (20%), Positives = 153/399 (38%), Gaps = 35/399 (8%)
Query: 18 EAQKLAEARLAAK-RAARAEAREIRMKELERQQKEVEERPEK--DFTEKGSRNMPGLS-- 72
EA + + L K R+ A +E K+L+ ++E+EE EK F + + + L
Sbjct: 1637 EAVRQEKQELYGKLRSTEANKKETE-KQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEE 1695
Query: 73 ----AATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNE 128
A + G T+ S + + + +K + +K++ M L E
Sbjct: 1696 NDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEE 1755
Query: 129 KTNFMYQVD--TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV-KEAL 185
+ +Q++ K LE E+ EE + E L E++
Sbjct: 1756 VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESV 1815
Query: 186 KQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLK 245
+ N ++ + + D +NN Y KE + L+ + +
Sbjct: 1816 PSAKS--------ANPAVSKDFSSHDEINN--YLQQIDQLKERIAGLEEEKQKNKEFS-Q 1864
Query: 246 KLVDERECLLEQIKKLKGQL----EERQKIGKLDNLRSED----DVLENGTDMHVMDLQR 297
L +E+ LL QI G+L EE K+ L+ E+ L+ + DL+
Sbjct: 1865 TLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEE 1924
Query: 298 DANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQR 357
Q+++L + Q++T + LES++ K E+ + +L EK K++
Sbjct: 1925 RLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVES 1984
Query: 358 ELRSA-LDKTE--ELEVSNGHLVKRLEKMKANRSALLSQ 393
E+R L+K + + E N K L+++ + + Q
Sbjct: 1985 EIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQ 2023
Score = 46.6 bits (109), Expect = 4e-05
Identities = 79/384 (20%), Positives = 161/384 (41%), Gaps = 41/384 (10%)
Query: 36 EAREIRMKELERQQKEVEERPE--KDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSI 93
+A+EI K L+ + KE+ + ++F + N SA T S + S+
Sbjct: 702 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNS---SAFTALSEERDQLLSQVKELSM 758
Query: 94 SIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT---LKDMLLE-LEEQ 149
+ A +++++ +LAE E + + S DN T ++ + KD+ +E L+ +
Sbjct: 759 VTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNE 818
Query: 150 LAESRRQYEEK------------NKEFEREKHAHSI--LQFQFAEVKEALKQREEMLEKH 195
L + + Q+ E+ NKE E + A + + + E+ +AL Q+E + K
Sbjct: 819 LDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM 878
Query: 196 GIIL---NSEIATNGETSDTLNNVGYQGPTKMTKE--ELNALKSTGDGTLDIRLKKLVDE 250
+L ++ T +T + + + MT++ +LN K + L + +K L ++
Sbjct: 879 DQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFS----LGVEIKTLKEQ 934
Query: 251 RECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKL 310
L + K Q+EE ++ L+ D + + +LQ + DL K
Sbjct: 935 LNLLSRAEEAKKEQVEEDNEVSS--GLKQNYDEMSPAGQISKEELQHEF-----DLLKK- 986
Query: 311 AKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
++EQ L+ +I + + R E ++DE K E + E + E E
Sbjct: 987 -ENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1045
Query: 371 VSNGHLVKRLEKMKANRSALLSQQ 394
S + + ++++ +S++
Sbjct: 1046 YSEKCVTSKCQEIEIYLKQTISEK 1069
Score = 46.6 bits (109), Expect = 4e-05
Identities = 57/268 (21%), Positives = 112/268 (41%), Gaps = 26/268 (9%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQY 157
E + E+ L E+E+K N L + +F + +L++ E+L E +R+Y
Sbjct: 2702 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2761
Query: 158 EEKNKEFEREKHAHSILQFQFAEVKE---ALKQREEMLEKHGIILNSEIATNGETSDTLN 214
+ KE + K + + + A + E ++ EE H LN ++ + E L+
Sbjct: 2762 DASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLS 2821
Query: 215 NVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKL 274
+ ++ N ++S + L +ER+ L +++K + E +Q+
Sbjct: 2822 S--------QLEDSYNQVQSFSKA-----MASLQNERDHLWNELEKFRKSEEGKQRSAAQ 2868
Query: 275 DNLRSEDDVLENGTDMHVMDLQRDANRQISDLK---FKLAKSEQEITALEQNVIRLESQV 331
S + LQ D +R + +LK + + QEIT L L++Q+
Sbjct: 2869 P---STSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHP----LKAQL 2921
Query: 332 SRYKSAAENAEKIEDELKAEKRKLQREL 359
Y+ + + +++EL+ E Q EL
Sbjct: 2922 QEYQDKTKAFQIMQEELRQENLSWQHEL 2949
Score = 44.3 bits (103), Expect = 2e-04
Identities = 87/400 (21%), Positives = 167/400 (41%), Gaps = 68/400 (17%)
Query: 20 QKLAEARLAAKRAARAEAREI-RMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
Q+ + RLA E ++I R K+++ QQK+ + E+ + + + + A L S
Sbjct: 47 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTS 106
Query: 79 L----------GGT-------SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYK--KAM 119
L GGT S + S S + E I +IK L E EE +A
Sbjct: 107 LNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQ 166
Query: 120 VSNAQLDN--EKTNFMYQVDTLKDMLLELEE-----QLAESRRQYEEKNKEFEREKHAHS 172
++ AQ + + + M + +K L E EE Q S+ Q E+ ++ REK A
Sbjct: 167 LTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARF 226
Query: 173 ILQFQF---------------AEVKEALKQREEMLEKH-----GIILNSEIATNGETSDT 212
Q + E+++ L+ + LE+H G ++ T+
Sbjct: 227 ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAE 286
Query: 213 LNNVGYQGPTKMTKEELNALKSTGDGTLD---IRLKKL---VDERECLLEQIKK-LKGQL 265
N + + E N L++T + + I L+K+ V ER+ +++ + L
Sbjct: 287 QRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLL 346
Query: 266 EERQKIGKLD-NLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITAL---- 320
E+ ++ G+ L S LE H +++ + +S L K+ QE+ +
Sbjct: 347 EQFEQAGQAQAELESRYSALEQ---KHKAEMEEKTSHILS-----LQKTGQELQSACDAL 398
Query: 321 -EQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQREL 359
+QN L+ + + +A+ +++ED+L+ + +++ + L
Sbjct: 399 KDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFL 438
Score = 39.7 bits (91), Expect = 0.005
Identities = 74/386 (19%), Positives = 157/386 (40%), Gaps = 49/386 (12%)
Query: 26 RLAAKRAARAEAREIRMKELERQQKE-VEERPEKDFTEKGSRNMPGLSAATLASLGGTSS 84
+L KRA A+ + KE+++ + E + K F E ++ P L +SL
Sbjct: 579 QLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFP-LMPNEESSLPAVEK 637
Query: 85 RRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLL 144
+ S + E S+ + L ++ K++ + + + +++ LK +L
Sbjct: 638 EQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQD---ELERLKSQIL 694
Query: 145 ELEEQLAESRRQYE----EKNKEF--------------EREKHAHSILQFQFAEVKEALK 186
ELE +++ YE EK KE + A + L + ++ +K
Sbjct: 695 ELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVK 754
Query: 187 QREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPT---KMTKEELNALKSTGDGTLDIR 243
+ + E + ++ N ++ + Y+ T + E++++L S + D++
Sbjct: 755 ELSMVTELRAQV--KQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSL-SIEAKSKDVK 811
Query: 244 LKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDM-HVMDLQRDANRQ 302
++ L +E + + Q + + Q +L N E +VLE + H+ + ++
Sbjct: 812 IEVLQNELDDVQLQFSEQSTLIRSLQ--SQLQN--KESEVLEGAERVRHISSKVEELSQA 867
Query: 303 ISDLKFKLAKSEQ-------EITALEQNVIRLESQVSRY------KSAAENAEK--IEDE 347
+S + ++ K +Q ++ L+Q + + QV+ K N EK + E
Sbjct: 868 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVE 927
Query: 348 LKAEKRKLQRELRSALDKTEELEVSN 373
+K K +L R+ K E++E N
Sbjct: 928 IKTLKEQLNLLSRAEEAKKEQVEEDN 953
Score = 38.9 bits (89), Expect = 0.008
Identities = 74/332 (22%), Positives = 137/332 (41%), Gaps = 42/332 (12%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQY 157
+ +I E + E+ + MV QL+ EK + ++ TLK+ L L + Q
Sbjct: 893 QQTIEEKDQQVTEISFSMTEKMV---QLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQV 949
Query: 158 EEKNK-------EFEREKHAHSI----LQFQFAEVKEALKQREEMLEKHGIILNSEIATN 206
EE N+ ++ A I LQ +F +K+ +QR+ L+ I +
Sbjct: 950 EEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRV 1009
Query: 207 GETSDTLNNV---------------GYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDER 251
+ L N+ G K KE ++ ++I LK+ + E+
Sbjct: 1010 SRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEK 1069
Query: 252 ECLLEQIKK-LKGQLEERQKIGKLDNLRSEDDVLENGTD-MHVMDLQRDANRQISD--LK 307
E L+ I+K L+ +L ++ L ++ + L++ T+ + ++ + N+ I +
Sbjct: 1070 EVELQHIRKDLEEKLAAEEQFQAL--VKQMNQTLQDKTNQIDLLQAEISENQAIIQKLIT 1127
Query: 308 FKLAKSEQEITAL--EQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDK 365
S+ + AL E VI S E EKI L+ EK +LQ++L+ AL
Sbjct: 1128 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKIL-ALEKEKEQLQKKLQEALTS 1186
Query: 366 TEEL----EVSNGHLVKRLEKMKANRSALLSQ 393
+ + + HL + L++ K + + L Q
Sbjct: 1187 RKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1218
Score = 36.2 bits (82), Expect = 0.053
Identities = 53/258 (20%), Positives = 100/258 (38%), Gaps = 19/258 (7%)
Query: 147 EEQLAESRRQYEEKNKEFEREKH-------AHSILQFQFAEVKEALKQREEMLEKHGIIL 199
EEQL++ + E+ E E+ KH S LQ Q + + + + +++
Sbjct: 129 EEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMM 188
Query: 200 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIK 259
++ E TL Q + +++ K D + +++ DE LL+ +
Sbjct: 189 KQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREK---DARFETQVRLHEDE---LLQLVT 242
Query: 260 KLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD---ANRQISDLKFKLAKSEQE 316
+ + E +QK+ L E + G V LQ++ A ++ L +L + E E
Sbjct: 243 QADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAE 302
Query: 317 ITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHL 376
L V E++ K E E E K LQ E+ L++ E+ + L
Sbjct: 303 HNTLRNTV---ETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAEL 359
Query: 377 VKRLEKMKANRSALLSQQ 394
R ++ A + ++
Sbjct: 360 ESRYSALEQKHKAEMEEK 377
Score = 29.6 bits (65), Expect = 4.9
Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 83 SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 142
+S G ++ +TE ++ DSL E+ +K + QL++ + + + +TL
Sbjct: 3013 TSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQ----QLNSNFSQLLEEKNTLSIQ 3068
Query: 143 LLELEEQLAESRRQY 157
L + + L E+++ Y
Sbjct: 3069 LCDTSQSLRENQQHY 3083
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 64.7 bits (156), Expect = 1e-10
Identities = 67/280 (23%), Positives = 124/280 (44%), Gaps = 26/280 (9%)
Query: 117 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 176
K ++ +A+ + E + KD L + E + R++ EEK +EK+ LQ
Sbjct: 840 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAK----RKELEEKMVTLLKEKND---LQL 892
Query: 177 QFAEVKEALKQREEMLE---KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK 233
Q ++L EE E K+ I L ++I E ++ + + K K E +
Sbjct: 893 QVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952
Query: 234 STGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVM 293
LKK +D+ E L +++K K E + K + + D+ +
Sbjct: 953 ----------LKKDIDDLELTLAKVEKEKHATENKVK-NLTEEMAGLDETIAK-LSKEKK 1000
Query: 294 DLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKR 353
LQ + + DL+ + E ++ L + +LE QV + + E +K+ +L+ KR
Sbjct: 1001 ALQETHQQTLDDLQAE----EDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKR 1056
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KL+ +L+ A + T ++E L ++LEK + S L+S+
Sbjct: 1057 KLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096
Score = 58.9 bits (141), Expect = 8e-09
Identities = 71/395 (17%), Positives = 165/395 (41%), Gaps = 40/395 (10%)
Query: 29 AKRAARAEAREIRMKELERQQKEVEE------RPEKDFTEKGSRNMPGLSA----ATLAS 78
AK A E ++K L + ++E + +K E + + L A + +
Sbjct: 965 AKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILT 1024
Query: 79 LGGTSSRRGSGDTSISIDTEASIR-EIKDSLAEVEEKYKKAMVSNAQLDNEK-------- 129
T + D S++ E +R +++ + ++E K A S ++N+K
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084
Query: 130 ------TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKE 183
+N + +++ + + ++L++++ E + + EE +E E E+ + + + Q +++
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144
Query: 184 ALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIR 243
L++ E LE+ G ++++ N + + + +L + +
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKL---------RRDLEEATLQHEAMVAAL 1195
Query: 244 LKKLVDERECLLEQI---KKLKGQLEERQKIGKL--DNLRSEDDVLENGTDMHVMDLQRD 298
KK D L EQI +++K +LE+ + K+ D+L S + + ++ + R
Sbjct: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKG-NLEKMCRS 1254
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
Q+S+LK K + ++ I L RL+++ Y + + + +L K+ ++
Sbjct: 1255 LEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQ 1314
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+ + EE + L L+ + + L Q
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQ 1349
Score = 56.6 bits (135), Expect = 4e-08
Identities = 66/299 (22%), Positives = 136/299 (45%), Gaps = 24/299 (8%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
D + ++ DSLA+ EE+ ++ + + QL+ + + +V + E+ +L +R
Sbjct: 889 DLQLQVQSEADSLADAEERCEQLIKNKIQLEAK----IKEVTERAEEEEEINAELTAKKR 944
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
+ E++ E +++ + + + K A + + + L + L+ IA + L
Sbjct: 945 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQE 1004
Query: 216 VGYQGPTKMTKEE--LNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGK 273
Q + EE +N L +L++ VD+ E LEQ KKL+ LE ++ +
Sbjct: 1005 THQQTLDDLQAEEDKVNILTKA-----KTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1059
Query: 274 LDNLRSEDDVLENGTDMHVMDLQRDANR-QISDLKFKLAKSEQEITALEQNVIRLESQVS 332
D +++ ++ D +D + + +IS+L K+ + L++ + L++++
Sbjct: 1060 GDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 1119
Query: 333 RYKSAAENAEKIEDE----LKAEKRK--LQRELRSALDKTEELEVSNGHLVKRLEKMKA 385
E E+IE E KAEK++ L REL ++ EE + V+ +K +A
Sbjct: 1120 ------ELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
Score = 55.5 bits (132), Expect = 8e-08
Identities = 96/444 (21%), Positives = 174/444 (39%), Gaps = 91/444 (20%)
Query: 6 AAQSREIDC--LSPEAQKLAEARLAAKRAARAEAREI-------------RMKELERQQK 50
A QS DC L + ++ E + +RA E+ R +ELE +K
Sbjct: 1335 ALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1394
Query: 51 EVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASI--------- 101
++ +R ++ + N A ASL T R + + +D E S
Sbjct: 1395 KLAQRLQEAEEHVEAVN------AKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKK 1448
Query: 102 -REIKDSLAEVEEKYKKAMVSNAQLDNEKTNF--------------MYQVDTLKDMLLEL 146
R L+E ++KY++ E + + Q++TL+ L
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNL 1508
Query: 147 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE-KHGIILNSEIAT 205
++++++ Q E K+ + ++ + E++ AL++ E LE + G IL ++
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 206 NGETSDTLNNVGYQGPTKMTKEELNALK-------STGDGTLDIRLKKLVDERECLLEQI 258
N S+ + + EE++ LK T TLD ++ R L
Sbjct: 1569 NQVKSEVDRKIAEK------DEEIDQLKRNHTRVVETMQSTLDAEIR----SRNDALRVK 1618
Query: 259 KKLKGQLEE---------RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFK 309
KK++G L E R L N R+ +L+ T +H+ DA R DLK +
Sbjct: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKE-TQLHL----DDALRGQEDLKEQ 1673
Query: 310 LAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEEL 369
LA E+ L+ + L + + + E + KI ++ EL A ++ + L
Sbjct: 1674 LAIVERRANLLQAEIEELWATLEQ----TERSRKIAEQ----------ELLDASERVQLL 1719
Query: 370 EVSNGHLVKRLEKMKANRSALLSQ 393
N L+ +K++ + S L S+
Sbjct: 1720 HTQNTSLINTKKKLENDVSQLQSE 1743
Score = 54.3 bits (129), Expect = 2e-07
Identities = 76/418 (18%), Positives = 174/418 (41%), Gaps = 58/418 (13%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+T +++D L ++ + R+ +RA R ++++ + E +++ +
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
EK + L + + ++ I + I+E++ + E+ E+ +
Sbjct: 1083 LEKKEFEISNLISKI------------EDEQAVEIQLQKKIKELQARIEELGEEIEAERA 1130
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLEL--------------EEQLAESRRQYEEKNKEFE- 165
S A+ + ++++ +++ + + L E E + + RR EE + E
Sbjct: 1131 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEA 1190
Query: 166 -----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQG 220
R+KHA S+ + E + L++ ++ LEK SE+ ET D +N
Sbjct: 1191 MVAALRKKHADSMAEL--GEQIDNLQRVKQKLEKE----KSELKM--ETDDLSSNAEAIS 1242
Query: 221 PTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSE 280
K E++ +S D +++ K+ +E++ L+ + + +L+ + G+ E
Sbjct: 1243 KAKGNLEKM--CRSLEDQVSELKTKE--EEQQRLINDLTAQRARLQT--EAGEYSRQLDE 1296
Query: 281 DDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAEN 340
D L + + ++ + +QI +LK +L + + AL + + E
Sbjct: 1297 KDALVS----QLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 341 AEKIEDELKAEKRKLQRELRS--------ALDKTEELEVSNGHLVKRLEKMKANRSAL 390
++ + EL+ K E+ A+ +TEELE + L +RL++ + + A+
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAV 1410
Score = 49.7 bits (117), Expect = 5e-06
Identities = 60/274 (21%), Positives = 112/274 (40%), Gaps = 54/274 (19%)
Query: 97 TEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ 156
TE S + + L + E+ + N L N K V L+ E+EE + ESR
Sbjct: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQS---EVEEVIQESRNA 1754
Query: 157 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNV 216
E+ K + +A EE+ ++ +TS L +
Sbjct: 1755 EEKAKKA-----------------ITDAAMMAEELKKEQ------------DTSAHLERM 1785
Query: 217 GYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDN 276
K ++ + L+ D + LK + + L ++++L+G++E QK
Sbjct: 1786 -----KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQK------ 1834
Query: 277 LRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKS 336
R+ + V G H R++ +L ++ + + + L+ V +L+++V YK
Sbjct: 1835 -RNAEAV--KGLRKH--------ERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKR 1883
Query: 337 AAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
AE AE+ + ++ RKLQ EL A ++ + E
Sbjct: 1884 QAEEAEEQSNANLSKFRKLQHELEEAEERADIAE 1917
Score = 48.1 bits (113), Expect = 1e-05
Identities = 85/379 (22%), Positives = 160/379 (42%), Gaps = 64/379 (16%)
Query: 44 ELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIRE 103
ELE QKE + F K TL + S T + I E
Sbjct: 1469 ELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE 1528
Query: 104 IKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKE 163
++ +VE++ + A L+ + + ++ + + LEL + +E R+ EK++E
Sbjct: 1529 LEKIKKQVEQEKCEIQ---AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1585
Query: 164 FEREKHAH--------SILQFQFAEVKEALKQREEM---LEKHGIILNSEIATNGETSDT 212
++ K H S L + +AL+ +++M L + I LN N +++
Sbjct: 1586 IDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH---ANRLAAES 1642
Query: 213 LNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQ--IKKLKGQLEERQK 270
L N Y+ + KE L G D++ + + ER L Q I++L LE+ ++
Sbjct: 1643 LRN--YRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTER 1700
Query: 271 IGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQ 330
K+ +E ++L+ + ++ Q N + + K KL E +V +L+S+
Sbjct: 1701 SRKI----AEQELLDASERVQLLHTQ---NTSLINTKKKL----------ENDVSQLQSE 1743
Query: 331 VSRYKSAAENAEK-----------IEDELKAE----------KRKLQ---RELRSALDKT 366
V + NAE+ + +ELK E K+ L+ ++L+ LD+
Sbjct: 1744 VEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1803
Query: 367 EELEVSNGHLVKRLEKMKA 385
E+L + G K+++K++A
Sbjct: 1804 EQLALKGGK--KQIQKLEA 1820
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/301 (20%), Positives = 134/301 (44%), Gaps = 16/301 (5%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD-TLKDMLLELEEQ---LA 151
+ + I ++K + V E + + + + N+ +++ L +M ++L A
Sbjct: 1581 EKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAA 1640
Query: 152 ESRRQYEEKNKEF-EREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEI----ATN 206
ES R Y E + H L+ Q E LK++ ++E+ +L +EI AT
Sbjct: 1641 ESLRNYRNTQGILKETQLHLDDALRGQ-----EDLKEQLAIVERRANLLQAEIEELWATL 1695
Query: 207 GETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE 266
+T + + + +L ++T +L+ V + + +E++ + E
Sbjct: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755
Query: 267 ERQKIGKLDN-LRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQ-EITALEQNV 324
E+ K D + +E+ E T H+ ++++ + + DL+ +L ++EQ + ++ +
Sbjct: 1756 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1815
Query: 325 IRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMK 384
+LE++V + EN +K E RK +R ++ +TEE + L ++K++
Sbjct: 1816 QKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQ 1875
Query: 385 A 385
A
Sbjct: 1876 A 1876
Score = 46.6 bits (109), Expect = 4e-05
Identities = 75/410 (18%), Positives = 174/410 (42%), Gaps = 67/410 (16%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
+ Q +EA A R E +LE + KEV ER E+
Sbjct: 891 QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEE------------------- 931
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD 137
+ I+ + A R+++D +E+++ ++ A+++ EK +V
Sbjct: 932 ------------EEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 979
Query: 138 TLKDMLLELEE---QLAESRRQYEEKNK------EFEREK-----HAHSILQFQFAEVKE 183
L + + L+E +L++ ++ +E ++ + E +K A + L+ Q +++
Sbjct: 980 NLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEG 1039
Query: 184 ALKQREEM---LEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELN----ALKSTG 236
+L+Q +++ LE+ L ++ E++ + N Q K+ K+E K
Sbjct: 1040 SLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIED 1099
Query: 237 DGTLDIRLKKLVDERECLLEQI-KKLKGQLEERQKIGK--LDNLRSEDDVLE-----NGT 288
+ ++I+L+K + E + +E++ ++++ + R K K D R +++ E G
Sbjct: 1100 EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1159
Query: 289 DMHVMDLQRDANRQISDLKFKLAKS----EQEITALEQNVIRLESQVSRYKSAAENAEKI 344
++L + + L+ L ++ E + AL + + ++ +N +++
Sbjct: 1160 TSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK---KHADSMAELGEQIDNLQRV 1216
Query: 345 EDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
+ +L+ EK +L+ E E + + G+L K ++ S L +++
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE 1266
Score = 30.8 bits (68), Expect = 2.2
Identities = 38/195 (19%), Positives = 81/195 (41%), Gaps = 19/195 (9%)
Query: 11 EIDCLSPEAQK-LAEARLAAKRAARAEAREIRMKELERQQKEVE---ERPEKDFTEKGSR 66
++ L E ++ + E+R A ++A +A M E +++++ ER +K+ +
Sbjct: 1736 DVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1795
Query: 67 NMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLD 126
L A +L G G I EA +RE++ + +++ +A+ + +
Sbjct: 1796 LQHRLDEAEQLALKG-------GKKQIQ-KLEARVRELEGEVENEQKRNAEAVKGLRKHE 1847
Query: 127 NEKTNFMYQVD-------TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFA 179
YQ + L+D++ +L+ ++ +RQ EE ++ LQ +
Sbjct: 1848 RRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELE 1907
Query: 180 EVKEALKQREEMLEK 194
E +E E + K
Sbjct: 1908 EAEERADIAESQVNK 1922
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 64.7 bits (156), Expect = 1e-10
Identities = 81/365 (22%), Positives = 148/365 (40%), Gaps = 24/365 (6%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTS 83
EA AA R A++ + EL Q ++ +K EK M LAS T
Sbjct: 1190 EATAAALRKKHADS----VAELGEQIDSLQRVKQKLEKEKSELKM---EINDLASNMETV 1242
Query: 84 SRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML 143
S+ + + E + EIK E + + A+L E F Q+D M+
Sbjct: 1243 SKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMV 1302
Query: 144 LELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEI 203
+L +Q EE ++ E E A S L + E E+ E
Sbjct: 1303 SQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE-------EQ 1355
Query: 204 ATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKG 263
E ++ + TK E +A++ T + L+ KKL + E ++ +
Sbjct: 1356 EAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEHVEAVNS 1413
Query: 264 QLEERQKIGKLDNLRSEDDVLE----NGTDMHVMDLQRDANRQISDLKFKLAKSEQEITA 319
+ +K + ED +++ N + + QR+ ++ +++ K K +++ E+ A
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
Query: 320 LEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKR 379
++ L +++ + K+A E + + LK E + LQ+E+ D TE++ H +
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEIS---DLTEQIAEGGKH-IHE 1529
Query: 380 LEKMK 384
LEK+K
Sbjct: 1530 LEKVK 1534
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/277 (23%), Positives = 124/277 (44%), Gaps = 26/277 (9%)
Query: 117 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 176
K ++ +A+ + E N + + K+ L + E + R++ EEK +EK+ LQ
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAK----RKELEEKMVTLMQEKND---LQL 893
Query: 177 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTG 236
Q +AL EE ++ ++ ++I + + +EE+NA +
Sbjct: 894 QVQAEADALADAEERCDQ---LIKTKIQLEAKIKEVTERAE-------DEEEINAELTAK 943
Query: 237 DGTLD---IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVM 293
L+ LKK +D+ E L +++K K E + K + + D+ + T
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK-NLTEEMAGLDETIAKLTK-EKK 1001
Query: 294 DLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKR 353
LQ + + DL+ + E ++ L + +LE QV + + E +K+ +L+ KR
Sbjct: 1002 ALQEAHQQTLDDLQME----EDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKR 1057
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSAL 390
KL+ +L+ A + T + E L ++L+K + S L
Sbjct: 1058 KLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNL 1094
Score = 60.1 bits (144), Expect = 3e-09
Identities = 75/424 (17%), Positives = 183/424 (43%), Gaps = 61/424 (14%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+T +++D L ++ + + +RA R ++++ + E +++ +
Sbjct: 1024 LTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEK 1083
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
+K M L + +++I + I+E++ + E+EE+ +
Sbjct: 1084 LKKKEFEMSNLQGKI------------EDEQALAIQLQKKIKELQARIEELEEEIEAERA 1131
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLEL--------------EEQLAESRRQYEEKNKEFE- 165
S A+ + ++++ +++ + + L E E + + RR EE + E
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEA 1191
Query: 166 -----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLN--NVGY 218
R+KHA S+ + E ++L++ ++ LEK L EI +T++ +
Sbjct: 1192 TAAALRKKHADSVA--ELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANF 1249
Query: 219 QGPTKMTKEELNALKSTGD----------------GTLDIRLKKLVDERECLLEQIKKLK 262
+ + +++L+ +K+ + T + +DE++ ++ Q+ +
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLS--R 1307
Query: 263 GQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITA-LE 321
G+ Q+I +L + E++ T H + + R DL + + EQE A L+
Sbjct: 1308 GKQAFTQQIEELKR-QLEEETKAKSTLAHAL----QSARHDCDLLREQYEEEQEAKAELQ 1362
Query: 322 QNVIRLESQVSRYKSAAE-NAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRL 380
+ + + S+V+++++ E +A + +EL+ K+KL + L+ A + E + L K
Sbjct: 1363 RGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK 1422
Query: 381 EKMK 384
++++
Sbjct: 1423 QRLQ 1426
Score = 57.4 bits (137), Expect = 2e-08
Identities = 68/337 (20%), Positives = 148/337 (43%), Gaps = 30/337 (8%)
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI------DTEASIREIKDSLAEVEEK 114
TEK NM T L T ++R + + D + ++ D+LA+ EE+
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 115 YKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 174
+ + + QL+ + + +V + E+ +L +R+ E++ E +++ +
Sbjct: 909 CDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 175 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNAL 232
+ + K A + + + L + L+ IA + L Q +M ++++N L
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
Query: 233 KSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHV 292
+L++ VD+ E LEQ KKL LE ++ + D +++ ++ D
Sbjct: 1025 TKA-----KTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTEND--- 1076
Query: 293 MDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEK 352
++ N ++ +F+++ + +I + I+L+ ++ K E++E+E++AE+
Sbjct: 1077 ---KQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKI---KELQARIEELEEEIEAER 1130
Query: 353 RKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
+ + D + ELE + +RLE+ SA
Sbjct: 1131 ASRAKAEKQRSDLSRELE----EISERLEEAGGATSA 1163
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/251 (22%), Positives = 112/251 (44%), Gaps = 18/251 (7%)
Query: 137 DTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK----QREEML 192
D LK+ L +E + + + EE ER + + + + + E ++ Q ++
Sbjct: 1669 DDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLI 1728
Query: 193 EKHGIILNSEIATNGETSDTLN---NVGYQGPTKMTKEELNA--LKSTGDGTLDI-RLKK 246
+ GE D + N + +T + A LK D + + R+KK
Sbjct: 1729 NTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1788
Query: 247 ----LVDERECLLEQIKKL--KGQLEERQKI-GKLDNLRSEDDVLENGTDMHVMDLQRDA 299
V + + L++ ++L KG ++ QK+ ++ L SE + E ++ + R
Sbjct: 1789 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVES-EQKHNVEAVKGLRKH 1847
Query: 300 NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQREL 359
R++ +L ++ + + I L+ V +L+++V YK AE AE+ + A+ RKLQ EL
Sbjct: 1848 ERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHEL 1907
Query: 360 RSALDKTEELE 370
A ++ + E
Sbjct: 1908 EEAKERADIAE 1918
Score = 50.4 bits (119), Expect = 3e-06
Identities = 73/334 (21%), Positives = 149/334 (44%), Gaps = 52/334 (15%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML-----------LEL 146
+ I ++ + +AE + + QLD+EK+ ++ + L LEL
Sbjct: 1510 QQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLEL 1569
Query: 147 EEQLAESRRQYEEKNKEFEREKHAH--------SILQFQFAEVKEALKQREEM---LEKH 195
+ +E R+ EK++E ++ K H S L + +AL+ +++M L +
Sbjct: 1570 NQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEM 1629
Query: 196 GIILNSEIATNGETSDTLNNV-GYQGPTKMTKEEL-NALKSTGDGTLDIRLKKLVDEREC 253
I LN N + ++ L N+ QG K T+ L +A++ G L +L +
Sbjct: 1630 EIQLNH---ANRQAAEALRNLRNTQGILKDTQLHLDDAIR--GQDDLKEQLAMVERRANL 1684
Query: 254 LLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKS 313
+ ++++L+ LE ++ K+ +E ++L+ + ++ Q N + + K KL
Sbjct: 1685 MQAEVEELRASLERTERGRKM----AEQELLDASERVQLLHTQ---NTSLINTKKKLETD 1737
Query: 314 EQEITA-LEQNVIRLESQVSRYKSAAENAEKIEDELKAE----------KRKLQ---REL 359
+I +E V + + K A +A + +ELK E K+ ++ ++L
Sbjct: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797
Query: 360 RSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+ LD+ E+L + G K+++K++A L S+
Sbjct: 1798 QLRLDEAEQLALKGGK--KQIQKLEARVRELESE 1829
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 240 LDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDA 299
L ++K L+ E E + + ++++ K + R E LE + +M + D
Sbjct: 836 LYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKE---LEEKM-VTLMQEKNDL 891
Query: 300 NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQREL 359
Q+ LA +E+ L + I+LE+++ AE+ E+I EL A+KRKL+ E
Sbjct: 892 QLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 951
Query: 360 RSALDKTEELEVSNGHLVKRLEKMK 384
++LE++ + ++EK K
Sbjct: 952 SELKKDIDDLELT----LAKVEKEK 972
Score = 30.0 bits (66), Expect = 3.8
Identities = 42/182 (23%), Positives = 74/182 (40%), Gaps = 20/182 (10%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVE---ERPEKDFTEKGSRNMPGLSAATLASLG 80
EAR A ++A +A M E +++++ ER +K+ + L A +L
Sbjct: 1751 EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALK 1810
Query: 81 GTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKT-NFMYQVD-- 137
G G I EA +RE+ +S E E+K+ V + + YQ +
Sbjct: 1811 G-------GKKQIQ-KLEARVREL-ESEVESEQKHNVEAVKGLRKHERRVKELTYQTEED 1861
Query: 138 -----TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 192
L+D++ +L+ ++ +RQ EE ++ LQ + E KE E +
Sbjct: 1862 RKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV 1921
Query: 193 EK 194
K
Sbjct: 1922 NK 1923
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 64.3 bits (155), Expect = 2e-10
Identities = 99/454 (21%), Positives = 187/454 (41%), Gaps = 82/454 (18%)
Query: 15 LSPEAQKLAE-ARLAAKRAARAEAREIRMKELERQQKEVEERPEK------DFTEKGSRN 67
L+ E +K +L K + E+R+K+ E+ ++E+E+ K DF E+ + +
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA-D 1073
Query: 68 MPGLSAATLASLGGTSSRRGSG----DTSISIDTEA--SIREIKDSLAEVEEKYKKAMVS 121
+ A L + D I+ A IRE++ +++++E +
Sbjct: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLE---------------------LEEQLAESRRQYEEK 160
+ + +K + +++ LK L + L++ L E R +E +
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 161 NKEFEREKHAHSILQF-----QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
+E R+KHA ++ + QF K L + ++ LEK L E+ G+ + +
Sbjct: 1194 VQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 216 VGYQGPTKMTKEELNALKSTGD---GTLDIRLKKLVDERECLLEQIKKLKG--------- 263
+ ++ +EL + S G+ L+ ++ KL +E E + + + +G
Sbjct: 1253 KKKKLEAQV--QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 264 --------------QLEERQKIG---KLDNLRSEDDVLENGTDMHV---MDLQRDA---N 300
Q E RQK+ KL L E + L++ D + +L+R N
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+SD K KL + ALE+ R + ++ E D+L+ K +LQ+EL
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
D +L+ + LV LEK + LL+++
Sbjct: 1431 ---DLVVDLD-NQRQLVSNLEKKQRKFDQLLAEE 1460
Score = 61.6 bits (148), Expect = 1e-09
Identities = 79/373 (21%), Positives = 163/373 (43%), Gaps = 41/373 (10%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAA 74
L + Q+L +++ + ARAE + ++ + Q EVE +G A
Sbjct: 1257 LEAQVQEL-QSKCSDGERARAELND----KVHKLQNEVESVTGMLNEAEGKAIKLAKDVA 1311
Query: 75 TLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS-----------NA 123
+L+S + +T ++ +R++++ ++++ + M + N
Sbjct: 1312 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371
Query: 124 QLDNEKT---NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
QL + K +F V+ L++ ++++ +QYEEK +++ + + LQ + +
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD 1431
Query: 181 VKEALKQREEM---LEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGD 237
+ L + ++ LEK + +A S + + + ++E AL
Sbjct: 1432 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL----- 1486
Query: 238 GTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
+L L++ ++ +E L K LK ++E D + S+DDV G ++H ++ +
Sbjct: 1487 -SLARALEEALEAKEELERTNKMLKAEME--------DLVSSKDDV---GKNVHELEKSK 1534
Query: 298 DA-NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK-L 355
A Q+ ++K +L + E E+ A E +RLE + K E + DE EKR+ L
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 356 QRELRSALDKTEE 368
QR+L + E+
Sbjct: 1595 QRQLHEYETELED 1607
Score = 59.7 bits (143), Expect = 4e-09
Identities = 83/369 (22%), Positives = 160/369 (43%), Gaps = 65/369 (17%)
Query: 33 ARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASL-GGTSSRRGSGDT 91
AR E E + ++L+RQ E E E + R L+AA L G D+
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDE------RKQRALAAAAKKKLEGDLKDLELQADS 1635
Query: 92 SISIDTEA--SIREIKDSLAEVEEKYKKAMVSNAQL-----DNEKTNFMYQVDTLKDMLL 144
+I EA +R+++ + + + + + A S ++ +NEK + +L+ L+
Sbjct: 1636 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK-----KAKSLEADLM 1690
Query: 145 ELEEQLAESRRQYEEKNKEFER--EKHAHSI------------LQFQFAEVKEALKQREE 190
+L+E LA + R ++ + E E E+ A S+ L+ + A+++E L++ +
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 191 MLE----------KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
+E + L++E+AT E S N + + +EL + +G +
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELAT--ERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
+ K + E + Q+++ Q E R+K +L+ +D L ++
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKSLKQKDKKL------------KEIL 1855
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+ D + K+A+ +E + ++V + K E AE+ + A +RKLQREL
Sbjct: 1856 LQVEDER-KMAEQYKE------QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 361 SALDKTEEL 369
A + E +
Sbjct: 1909 EATESNEAM 1917
Score = 58.9 bits (141), Expect = 8e-09
Identities = 100/444 (22%), Positives = 184/444 (41%), Gaps = 76/444 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGL 71
E + L + +L A+ AEA E+R++ ELE E+E R E++ ++G +
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEE-EDRGQQLQAER 945
Query: 72 S--AATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKA-------- 118
A + L + + ++ EA I++++D + ++++ K
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 119 -----MVSNAQLDNEKT-NFMYQVDTLKDMLLELEEQL---AESRRQYEEKNKEFERE-- 167
+ +N + EK N + + M+ ELE +L +SR++ E+ ++ E +
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 168 --KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA-----------TNGETSDTLN 214
+ LQ Q AE+K L ++EE L+ L+ EIA G SD
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 215 NVGYQGPTKMTK--------EELNALKSTGDGTLDI----------RLKKLVDERECLLE 256
++ + + EEL ALK+ + TLD R +++ ++ L E
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 257 QIKKLKGQLEE-RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQI-----SDLKFKL 310
+ + + Q++E RQK + ++ +++ E D N+Q +DL +L
Sbjct: 1186 ETRSHEAQVQEMRQK-----HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1240
Query: 311 AKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
Q +E +LE+QV +S + E+ EL + KLQ E+ S E E
Sbjct: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 371 VSNGHLVKRLEKMKANRSALLSQQ 394
G +K + + + S L Q
Sbjct: 1301 ---GKAIKLAKDVASLSSQLQDTQ 1321
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/301 (22%), Positives = 130/301 (43%), Gaps = 43/301 (14%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE---QLAESR 154
E +++ K+ + E + K+ ++QL EK Q+ ++ E EE +LA +
Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 155 RQYEEKNKEFE----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 210
++ EE E E E+ LQ + ++ + + EE LE+ E A +
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE-------EEAARQKLQ 970
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL-EERQ 269
L V + K ++E+ + D + KL ER+ L E+I L L EE +
Sbjct: 971 --LEKVTAEAKIKKLEDEILVM--------DDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
Query: 270 KIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLES 329
K L L+++ + + IS+L+ +L K E+ LE+ +LE
Sbjct: 1021 KAKNLTKLKNKHESM------------------ISELEVRLKKEEKSRQELEKLKRKLEG 1062
Query: 330 QVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
S + + + ELK + K + EL++AL + ++ + +K++ +++ + S
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1122
Query: 390 L 390
L
Sbjct: 1123 L 1123
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/293 (23%), Positives = 126/293 (43%), Gaps = 43/293 (14%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
D E + E+ D + +++ + + + + + V +L L + +E L E R
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
Q + + + + + LQ Q E EA ++ LE+H LN +++ +
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEA----KQNLERHISTLNIQLSDS--------- 1376
Query: 216 VGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLD 275
K++L ST ++ L + ++ ++I+ L Q EE K D
Sbjct: 1377 ----------KKKLQDFAST--------VEALEEGKKRFQKEIENLTQQYEE--KAAAYD 1416
Query: 276 NLRSEDDVLENGTDMHVMDLQRDANRQ-ISDLKFKLAKSEQEITALEQNVIRLESQVSRY 334
L + L+ D V+DL D RQ +S+L+ K K +Q + A E+N+ S+Y
Sbjct: 1417 KLEKTKNRLQQELDDLVVDL--DNQRQLVSNLEKKQRKFDQ-LLAEEKNIS------SKY 1467
Query: 335 KSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANR 387
+ AE E + + L R L AL+ EELE +N L +E + +++
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Score = 54.3 bits (129), Expect = 2e-07
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 26/380 (6%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + ++ + A AEARE K L + E K+
Sbjct: 1442 LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ ++ + ++S + S E + E+K L E+E++ +
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA-LETQMEEMKTQLEELEDELQATED 1560
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
+ +L+ N + L +EQ E RRQ + + E+E E + A
Sbjct: 1561 AKLRLE---VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
K+ L+ + LE L ++ A G Q K + EL +++ D +
Sbjct: 1618 AKKKLEGDLKDLE-----LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD-EI 1671
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
K+ + + L + +L+ L ++ K +L E+ E + + + +D
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1731
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEK-------- 352
R+ L+ ++A+ E+E LE+ +E+ R + A + AE++ +EL E+
Sbjct: 1732 RR---LEARIAQLEEE---LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 353 --RKLQRELRSALDKTEELE 370
++L+R+ + K E+E
Sbjct: 1786 ARQQLERQNKELRSKLHEME 1805
Score = 52.4 bits (124), Expect = 7e-07
Identities = 62/284 (21%), Positives = 122/284 (42%), Gaps = 44/284 (15%)
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHS-------ILQFQFAEV 181
K + QV ++ + E++L +++ + ++ E + + HS +LQ Q
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLD 241
E + EEM + L + ++ ++ +EE
Sbjct: 900 TELYAEAEEMRVR-----------LAAKKQELEEILHEMEARLEEEE------------- 935
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEE----RQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
R ++L ER+ + +Q+ L+ QLEE RQK+ +L+ + +E + + ++ VMD Q
Sbjct: 936 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL-QLEKVTAEAKIKKLEDEILVMDDQN 994
Query: 298 D--------ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELK 349
+ +ISDL LA+ E++ L + + ES +S + + EK EL+
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 350 AEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KRKL+ + ++ +L+ L +L K + A L++
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Score = 50.4 bits (119), Expect = 3e-06
Identities = 75/406 (18%), Positives = 167/406 (41%), Gaps = 42/406 (10%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
++++ LS + Q E R + ++R E ER + + E + + R++
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDT-EASIREIKDSLAEVEEKYKKAMVSNAQLDN 127
L+ + S++ D + +++ E + + + + ++Y++ + +L+
Sbjct: 1367 STLNIQL------SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Query: 128 EKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQ 187
K ++D D++++L+ Q + E+K ++F++ + ++A+ ++ +
Sbjct: 1421 TKNRLQQELD---DLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 1476
Query: 188 REEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKL 247
E + L + E + L KM K E+ L S+ D + + +L
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTN-----KMLKAEMEDLVSSKDD-VGKNVHEL 1530
Query: 248 VDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDV-LENGTDMHVM------DLQ---- 296
+ L Q++++K QLEE + D L++ +D L +M + DLQ
Sbjct: 1531 EKSKRALETQMEEMKTQLEELE-----DELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 297 ------RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
R RQ+ + + +L ++ +LE + + A++A K +E
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 351 EKRKLQRELRSALDKTEELEVSNGHL---VKRLEKMKANRSALLSQ 393
+ RKLQ +++ + E+ S + K EK + A L Q
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1691
Score = 35.8 bits (81), Expect = 0.069
Identities = 47/211 (22%), Positives = 90/211 (42%), Gaps = 36/211 (17%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSR 66
A S + + +A++L+ LA +R+ A+ E ++LERQ KE+ + + S+
Sbjct: 1754 AMSDRVRKATQQAEQLSN-ELATERST-AQKNESARQQLERQNKELRSKLHEMEGAVKSK 1811
Query: 67 NMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLD 126
+T+A+L EA I ++++ + + + + A S Q D
Sbjct: 1812 -----FKSTIAAL------------------EAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 127 NEKTNFMYQVDTLKDMLLELEEQ-------LAESRRQYEEKNKEFEREKHAHSILQFQFA 179
+ + QV+ + M + +EQ + + +RQ EE +E +R LQ +
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETS 210
E E+ E + + L S++ ETS
Sbjct: 1909 EATES----NEAMGREVNALKSKLRRGNETS 1935
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 64.3 bits (155), Expect = 2e-10
Identities = 99/454 (21%), Positives = 187/454 (41%), Gaps = 82/454 (18%)
Query: 15 LSPEAQKLAE-ARLAAKRAARAEAREIRMKELERQQKEVEERPEK------DFTEKGSRN 67
L+ E +K +L K + E+R+K+ E+ ++E+E+ K DF E+ + +
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA-D 1080
Query: 68 MPGLSAATLASLGGTSSRRGSG----DTSISIDTEA--SIREIKDSLAEVEEKYKKAMVS 121
+ A L + D I+ A IRE++ +++++E +
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLE---------------------LEEQLAESRRQYEEK 160
+ + +K + +++ LK L + L++ L E R +E +
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 161 NKEFEREKHAHSILQF-----QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
+E R+KHA ++ + QF K L + ++ LEK L E+ G+ + +
Sbjct: 1201 VQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1259
Query: 216 VGYQGPTKMTKEELNALKSTGD---GTLDIRLKKLVDERECLLEQIKKLKG--------- 263
+ ++ +EL + S G+ L+ ++ KL +E E + + + +G
Sbjct: 1260 KKKKLEAQV--QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 264 --------------QLEERQKIG---KLDNLRSEDDVLENGTDMHV---MDLQRDA---N 300
Q E RQK+ KL L E + L++ D + +L+R N
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+SD K KL + ALE+ R + ++ E D+L+ K +LQ+EL
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
D +L+ + LV LEK + LL+++
Sbjct: 1438 ---DLVVDLD-NQRQLVSNLEKKQRKFDQLLAEE 1467
Score = 61.6 bits (148), Expect = 1e-09
Identities = 79/373 (21%), Positives = 163/373 (43%), Gaps = 41/373 (10%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAA 74
L + Q+L +++ + ARAE + ++ + Q EVE +G A
Sbjct: 1264 LEAQVQEL-QSKCSDGERARAELND----KVHKLQNEVESVTGMLNEAEGKAIKLAKDVA 1318
Query: 75 TLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS-----------NA 123
+L+S + +T ++ +R++++ ++++ + M + N
Sbjct: 1319 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378
Query: 124 QLDNEKT---NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
QL + K +F V+ L++ ++++ +QYEEK +++ + + LQ + +
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD 1438
Query: 181 VKEALKQREEM---LEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGD 237
+ L + ++ LEK + +A S + + + ++E AL
Sbjct: 1439 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL----- 1493
Query: 238 GTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
+L L++ ++ +E L K LK ++E D + S+DDV G ++H ++ +
Sbjct: 1494 -SLARALEEALEAKEELERTNKMLKAEME--------DLVSSKDDV---GKNVHELEKSK 1541
Query: 298 DA-NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK-L 355
A Q+ ++K +L + E E+ A E +RLE + K E + DE EKR+ L
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 356 QRELRSALDKTEE 368
QR+L + E+
Sbjct: 1602 QRQLHEYETELED 1614
Score = 59.7 bits (143), Expect = 4e-09
Identities = 83/369 (22%), Positives = 160/369 (43%), Gaps = 65/369 (17%)
Query: 33 ARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASL-GGTSSRRGSGDT 91
AR E E + ++L+RQ E E E + R L+AA L G D+
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDE------RKQRALAAAAKKKLEGDLKDLELQADS 1642
Query: 92 SISIDTEA--SIREIKDSLAEVEEKYKKAMVSNAQL-----DNEKTNFMYQVDTLKDMLL 144
+I EA +R+++ + + + + + A S ++ +NEK + +L+ L+
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK-----KAKSLEADLM 1697
Query: 145 ELEEQLAESRRQYEEKNKEFER--EKHAHSI------------LQFQFAEVKEALKQREE 190
+L+E LA + R ++ + E E E+ A S+ L+ + A+++E L++ +
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757
Query: 191 MLE----------KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
+E + L++E+AT E S N + + +EL + +G +
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELAT--ERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
+ K + E + Q+++ Q E R+K +L+ +D L ++
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKSLKQKDKKL------------KEIL 1862
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+ D + K+A+ +E + ++V + K E AE+ + A +RKLQREL
Sbjct: 1863 LQVEDER-KMAEQYKE------QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1915
Query: 361 SALDKTEEL 369
A + E +
Sbjct: 1916 EATESNEAM 1924
Score = 58.9 bits (141), Expect = 8e-09
Identities = 100/444 (22%), Positives = 184/444 (41%), Gaps = 76/444 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGL 71
E + L + +L A+ AEA E+R++ ELE E+E R E++ ++G +
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEE-EDRGQQLQAER 952
Query: 72 S--AATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKA-------- 118
A + L + + ++ EA I++++D + ++++ K
Sbjct: 953 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Query: 119 -----MVSNAQLDNEKT-NFMYQVDTLKDMLLELEEQL---AESRRQYEEKNKEFERE-- 167
+ +N + EK N + + M+ ELE +L +SR++ E+ ++ E +
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 168 --KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA-----------TNGETSDTLN 214
+ LQ Q AE+K L ++EE L+ L+ EIA G SD
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 215 NVGYQGPTKMTK--------EELNALKSTGDGTLDI----------RLKKLVDERECLLE 256
++ + + EEL ALK+ + TLD R +++ ++ L E
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 257 QIKKLKGQLEE-RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQI-----SDLKFKL 310
+ + + Q++E RQK + ++ +++ E D N+Q +DL +L
Sbjct: 1193 ETRSHEAQVQEMRQK-----HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1247
Query: 311 AKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
Q +E +LE+QV +S + E+ EL + KLQ E+ S E E
Sbjct: 1248 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1307
Query: 371 VSNGHLVKRLEKMKANRSALLSQQ 394
G +K + + + S L Q
Sbjct: 1308 ---GKAIKLAKDVASLSSQLQDTQ 1328
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/301 (22%), Positives = 130/301 (43%), Gaps = 43/301 (14%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE---QLAESR 154
E +++ K+ + E + K+ ++QL EK Q+ ++ E EE +LA +
Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 155 RQYEEKNKEFE----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 210
++ EE E E E+ LQ + ++ + + EE LE+ E A +
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE-------EEAARQKLQ 977
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL-EERQ 269
L V + K ++E+ + D + KL ER+ L E+I L L EE +
Sbjct: 978 --LEKVTAEAKIKKLEDEILVM--------DDQNNKLSKERKLLEERISDLTTNLAEEEE 1027
Query: 270 KIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLES 329
K L L+++ + + IS+L+ +L K E+ LE+ +LE
Sbjct: 1028 KAKNLTKLKNKHESM------------------ISELEVRLKKEEKSRQELEKLKRKLEG 1069
Query: 330 QVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
S + + + ELK + K + EL++AL + ++ + +K++ +++ + S
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1129
Query: 390 L 390
L
Sbjct: 1130 L 1130
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/293 (23%), Positives = 126/293 (43%), Gaps = 43/293 (14%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
D E + E+ D + +++ + + + + + V +L L + +E L E R
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
Q + + + + + LQ Q E EA ++ LE+H LN +++ +
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEA----KQNLERHISTLNIQLSDS--------- 1383
Query: 216 VGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLD 275
K++L ST ++ L + ++ ++I+ L Q EE K D
Sbjct: 1384 ----------KKKLQDFAST--------VEALEEGKKRFQKEIENLTQQYEE--KAAAYD 1423
Query: 276 NLRSEDDVLENGTDMHVMDLQRDANRQ-ISDLKFKLAKSEQEITALEQNVIRLESQVSRY 334
L + L+ D V+DL D RQ +S+L+ K K +Q + A E+N+ S+Y
Sbjct: 1424 KLEKTKNRLQQELDDLVVDL--DNQRQLVSNLEKKQRKFDQ-LLAEEKNIS------SKY 1474
Query: 335 KSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANR 387
+ AE E + + L R L AL+ EELE +N L +E + +++
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1527
Score = 54.3 bits (129), Expect = 2e-07
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 26/380 (6%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + ++ + A AEARE K L + E K+
Sbjct: 1449 LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1508
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ ++ + ++S + S E + E+K L E+E++ +
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA-LETQMEEMKTQLEELEDELQATED 1567
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
+ +L+ N + L +EQ E RRQ + + E+E E + A
Sbjct: 1568 AKLRLE---VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
K+ L+ + LE L ++ A G Q K + EL +++ D +
Sbjct: 1625 AKKKLEGDLKDLE-----LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD-EI 1678
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
K+ + + L + +L+ L ++ K +L E+ E + + + +D
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1738
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEK-------- 352
R+ L+ ++A+ E+E LE+ +E+ R + A + AE++ +EL E+
Sbjct: 1739 RR---LEARIAQLEEE---LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 353 --RKLQRELRSALDKTEELE 370
++L+R+ + K E+E
Sbjct: 1793 ARQQLERQNKELRSKLHEME 1812
Score = 52.4 bits (124), Expect = 7e-07
Identities = 62/284 (21%), Positives = 122/284 (42%), Gaps = 44/284 (15%)
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHS-------ILQFQFAEV 181
K + QV ++ + E++L +++ + ++ E + + HS +LQ Q
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLD 241
E + EEM + L + ++ ++ +EE
Sbjct: 907 TELYAEAEEMRVR-----------LAAKKQELEEILHEMEARLEEEE------------- 942
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEE----RQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
R ++L ER+ + +Q+ L+ QLEE RQK+ +L+ + +E + + ++ VMD Q
Sbjct: 943 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL-QLEKVTAEAKIKKLEDEILVMDDQN 1001
Query: 298 D--------ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELK 349
+ +ISDL LA+ E++ L + + ES +S + + EK EL+
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 350 AEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KRKL+ + ++ +L+ L +L K + A L++
Sbjct: 1062 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Score = 50.4 bits (119), Expect = 3e-06
Identities = 75/406 (18%), Positives = 167/406 (41%), Gaps = 42/406 (10%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
++++ LS + Q E R + ++R E ER + + E + + R++
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDT-EASIREIKDSLAEVEEKYKKAMVSNAQLDN 127
L+ + S++ D + +++ E + + + + ++Y++ + +L+
Sbjct: 1374 STLNIQL------SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Query: 128 EKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQ 187
K ++D D++++L+ Q + E+K ++F++ + ++A+ ++ +
Sbjct: 1428 TKNRLQQELD---DLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 1483
Query: 188 REEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKL 247
E + L + E + L KM K E+ L S+ D + + +L
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTN-----KMLKAEMEDLVSSKDD-VGKNVHEL 1537
Query: 248 VDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDV-LENGTDMHVM------DLQ---- 296
+ L Q++++K QLEE + D L++ +D L +M + DLQ
Sbjct: 1538 EKSKRALETQMEEMKTQLEELE-----DELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 297 ------RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
R RQ+ + + +L ++ +LE + + A++A K +E
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 351 EKRKLQRELRSALDKTEELEVSNGHL---VKRLEKMKANRSALLSQ 393
+ RKLQ +++ + E+ S + K EK + A L Q
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1698
Score = 35.8 bits (81), Expect = 0.069
Identities = 47/211 (22%), Positives = 90/211 (42%), Gaps = 36/211 (17%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSR 66
A S + + +A++L+ LA +R+ A+ E ++LERQ KE+ + + S+
Sbjct: 1761 AMSDRVRKATQQAEQLSN-ELATERST-AQKNESARQQLERQNKELRSKLHEMEGAVKSK 1818
Query: 67 NMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLD 126
+T+A+L EA I ++++ + + + + A S Q D
Sbjct: 1819 -----FKSTIAAL------------------EAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 127 NEKTNFMYQVDTLKDMLLELEEQ-------LAESRRQYEEKNKEFEREKHAHSILQFQFA 179
+ + QV+ + M + +EQ + + +RQ EE +E +R LQ +
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1915
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETS 210
E E+ E + + L S++ ETS
Sbjct: 1916 EATES----NEAMGREVNALKSKLRRGNETS 1942
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 64.3 bits (155), Expect = 2e-10
Identities = 99/454 (21%), Positives = 187/454 (41%), Gaps = 82/454 (18%)
Query: 15 LSPEAQKLAE-ARLAAKRAARAEAREIRMKELERQQKEVEERPEK------DFTEKGSRN 67
L+ E +K +L K + E+R+K+ E+ ++E+E+ K DF E+ + +
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA-D 1080
Query: 68 MPGLSAATLASLGGTSSRRGSG----DTSISIDTEA--SIREIKDSLAEVEEKYKKAMVS 121
+ A L + D I+ A IRE++ +++++E +
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLE---------------------LEEQLAESRRQYEEK 160
+ + +K + +++ LK L + L++ L E R +E +
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 161 NKEFEREKHAHSILQF-----QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
+E R+KHA ++ + QF K L + ++ LEK L E+ G+ + +
Sbjct: 1201 VQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1259
Query: 216 VGYQGPTKMTKEELNALKSTGD---GTLDIRLKKLVDERECLLEQIKKLKG--------- 263
+ ++ +EL + S G+ L+ ++ KL +E E + + + +G
Sbjct: 1260 KKKKLEAQV--QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 264 --------------QLEERQKIG---KLDNLRSEDDVLENGTDMHV---MDLQRDA---N 300
Q E RQK+ KL L E + L++ D + +L+R N
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+SD K KL + ALE+ R + ++ E D+L+ K +LQ+EL
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
D +L+ + LV LEK + LL+++
Sbjct: 1438 ---DLVVDLD-NQRQLVSNLEKKQRKFDQLLAEE 1467
Score = 61.6 bits (148), Expect = 1e-09
Identities = 79/373 (21%), Positives = 163/373 (43%), Gaps = 41/373 (10%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAA 74
L + Q+L +++ + ARAE + ++ + Q EVE +G A
Sbjct: 1264 LEAQVQEL-QSKCSDGERARAELND----KVHKLQNEVESVTGMLNEAEGKAIKLAKDVA 1318
Query: 75 TLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS-----------NA 123
+L+S + +T ++ +R++++ ++++ + M + N
Sbjct: 1319 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378
Query: 124 QLDNEKT---NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
QL + K +F V+ L++ ++++ +QYEEK +++ + + LQ + +
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD 1438
Query: 181 VKEALKQREEM---LEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGD 237
+ L + ++ LEK + +A S + + + ++E AL
Sbjct: 1439 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL----- 1493
Query: 238 GTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
+L L++ ++ +E L K LK ++E D + S+DDV G ++H ++ +
Sbjct: 1494 -SLARALEEALEAKEELERTNKMLKAEME--------DLVSSKDDV---GKNVHELEKSK 1541
Query: 298 DA-NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK-L 355
A Q+ ++K +L + E E+ A E +RLE + K E + DE EKR+ L
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 356 QRELRSALDKTEE 368
QR+L + E+
Sbjct: 1602 QRQLHEYETELED 1614
Score = 59.7 bits (143), Expect = 4e-09
Identities = 83/369 (22%), Positives = 160/369 (43%), Gaps = 65/369 (17%)
Query: 33 ARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASL-GGTSSRRGSGDT 91
AR E E + ++L+RQ E E E + R L+AA L G D+
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDE------RKQRALAAAAKKKLEGDLKDLELQADS 1642
Query: 92 SISIDTEA--SIREIKDSLAEVEEKYKKAMVSNAQL-----DNEKTNFMYQVDTLKDMLL 144
+I EA +R+++ + + + + + A S ++ +NEK + +L+ L+
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK-----KAKSLEADLM 1697
Query: 145 ELEEQLAESRRQYEEKNKEFER--EKHAHSI------------LQFQFAEVKEALKQREE 190
+L+E LA + R ++ + E E E+ A S+ L+ + A+++E L++ +
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757
Query: 191 MLE----------KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
+E + L++E+AT E S N + + +EL + +G +
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELAT--ERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
+ K + E + Q+++ Q E R+K +L+ +D L ++
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKSLKQKDKKL------------KEIL 1862
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+ D + K+A+ +E + ++V + K E AE+ + A +RKLQREL
Sbjct: 1863 LQVEDER-KMAEQYKE------QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1915
Query: 361 SALDKTEEL 369
A + E +
Sbjct: 1916 EATESNEAM 1924
Score = 58.9 bits (141), Expect = 8e-09
Identities = 100/444 (22%), Positives = 184/444 (41%), Gaps = 76/444 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGL 71
E + L + +L A+ AEA E+R++ ELE E+E R E++ ++G +
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEE-EDRGQQLQAER 952
Query: 72 S--AATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKA-------- 118
A + L + + ++ EA I++++D + ++++ K
Sbjct: 953 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Query: 119 -----MVSNAQLDNEKT-NFMYQVDTLKDMLLELEEQL---AESRRQYEEKNKEFERE-- 167
+ +N + EK N + + M+ ELE +L +SR++ E+ ++ E +
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 168 --KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA-----------TNGETSDTLN 214
+ LQ Q AE+K L ++EE L+ L+ EIA G SD
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 215 NVGYQGPTKMTK--------EELNALKSTGDGTLDI----------RLKKLVDERECLLE 256
++ + + EEL ALK+ + TLD R +++ ++ L E
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 257 QIKKLKGQLEE-RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQI-----SDLKFKL 310
+ + + Q++E RQK + ++ +++ E D N+Q +DL +L
Sbjct: 1193 ETRSHEAQVQEMRQK-----HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1247
Query: 311 AKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
Q +E +LE+QV +S + E+ EL + KLQ E+ S E E
Sbjct: 1248 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1307
Query: 371 VSNGHLVKRLEKMKANRSALLSQQ 394
G +K + + + S L Q
Sbjct: 1308 ---GKAIKLAKDVASLSSQLQDTQ 1328
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/301 (22%), Positives = 130/301 (43%), Gaps = 43/301 (14%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE---QLAESR 154
E +++ K+ + E + K+ ++QL EK Q+ ++ E EE +LA +
Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 155 RQYEEKNKEFE----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 210
++ EE E E E+ LQ + ++ + + EE LE+ E A +
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE-------EEAARQKLQ 977
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL-EERQ 269
L V + K ++E+ + D + KL ER+ L E+I L L EE +
Sbjct: 978 --LEKVTAEAKIKKLEDEILVM--------DDQNNKLSKERKLLEERISDLTTNLAEEEE 1027
Query: 270 KIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLES 329
K L L+++ + + IS+L+ +L K E+ LE+ +LE
Sbjct: 1028 KAKNLTKLKNKHESM------------------ISELEVRLKKEEKSRQELEKLKRKLEG 1069
Query: 330 QVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
S + + + ELK + K + EL++AL + ++ + +K++ +++ + S
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1129
Query: 390 L 390
L
Sbjct: 1130 L 1130
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/293 (23%), Positives = 126/293 (43%), Gaps = 43/293 (14%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
D E + E+ D + +++ + + + + + V +L L + +E L E R
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
Q + + + + + LQ Q E EA ++ LE+H LN +++ +
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEA----KQNLERHISTLNIQLSDS--------- 1383
Query: 216 VGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLD 275
K++L ST ++ L + ++ ++I+ L Q EE K D
Sbjct: 1384 ----------KKKLQDFAST--------VEALEEGKKRFQKEIENLTQQYEE--KAAAYD 1423
Query: 276 NLRSEDDVLENGTDMHVMDLQRDANRQ-ISDLKFKLAKSEQEITALEQNVIRLESQVSRY 334
L + L+ D V+DL D RQ +S+L+ K K +Q + A E+N+ S+Y
Sbjct: 1424 KLEKTKNRLQQELDDLVVDL--DNQRQLVSNLEKKQRKFDQ-LLAEEKNIS------SKY 1474
Query: 335 KSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANR 387
+ AE E + + L R L AL+ EELE +N L +E + +++
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1527
Score = 54.3 bits (129), Expect = 2e-07
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 26/380 (6%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + ++ + A AEARE K L + E K+
Sbjct: 1449 LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1508
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ ++ + ++S + S E + E+K L E+E++ +
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA-LETQMEEMKTQLEELEDELQATED 1567
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
+ +L+ N + L +EQ E RRQ + + E+E E + A
Sbjct: 1568 AKLRLE---VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
K+ L+ + LE L ++ A G Q K + EL +++ D +
Sbjct: 1625 AKKKLEGDLKDLE-----LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD-EI 1678
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
K+ + + L + +L+ L ++ K +L E+ E + + + +D
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1738
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEK-------- 352
R+ L+ ++A+ E+E LE+ +E+ R + A + AE++ +EL E+
Sbjct: 1739 RR---LEARIAQLEEE---LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 353 --RKLQRELRSALDKTEELE 370
++L+R+ + K E+E
Sbjct: 1793 ARQQLERQNKELRSKLHEME 1812
Score = 52.4 bits (124), Expect = 7e-07
Identities = 62/284 (21%), Positives = 122/284 (42%), Gaps = 44/284 (15%)
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHS-------ILQFQFAEV 181
K + QV ++ + E++L +++ + ++ E + + HS +LQ Q
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLD 241
E + EEM + L + ++ ++ +EE
Sbjct: 907 TELYAEAEEMRVR-----------LAAKKQELEEILHEMEARLEEEE------------- 942
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEE----RQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
R ++L ER+ + +Q+ L+ QLEE RQK+ +L+ + +E + + ++ VMD Q
Sbjct: 943 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL-QLEKVTAEAKIKKLEDEILVMDDQN 1001
Query: 298 D--------ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELK 349
+ +ISDL LA+ E++ L + + ES +S + + EK EL+
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 350 AEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KRKL+ + ++ +L+ L +L K + A L++
Sbjct: 1062 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Score = 50.4 bits (119), Expect = 3e-06
Identities = 75/406 (18%), Positives = 167/406 (41%), Gaps = 42/406 (10%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
++++ LS + Q E R + ++R E ER + + E + + R++
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1373
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDT-EASIREIKDSLAEVEEKYKKAMVSNAQLDN 127
L+ + S++ D + +++ E + + + + ++Y++ + +L+
Sbjct: 1374 STLNIQL------SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Query: 128 EKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQ 187
K ++D D++++L+ Q + E+K ++F++ + ++A+ ++ +
Sbjct: 1428 TKNRLQQELD---DLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 1483
Query: 188 REEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKL 247
E + L + E + L KM K E+ L S+ D + + +L
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTN-----KMLKAEMEDLVSSKDD-VGKNVHEL 1537
Query: 248 VDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDV-LENGTDMHVM------DLQ---- 296
+ L Q++++K QLEE + D L++ +D L +M + DLQ
Sbjct: 1538 EKSKRALETQMEEMKTQLEELE-----DELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 297 ------RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
R RQ+ + + +L ++ +LE + + A++A K +E
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 351 EKRKLQRELRSALDKTEELEVSNGHL---VKRLEKMKANRSALLSQ 393
+ RKLQ +++ + E+ S + K EK + A L Q
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1698
Score = 33.5 bits (75), Expect = 0.34
Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 35/192 (18%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSR 66
A S + + +A++L+ LA +R+ A+ E ++LERQ KE+ + + S+
Sbjct: 1761 AMSDRVRKATQQAEQLSN-ELATERST-AQKNESARQQLERQNKELRSKLHEMEGAVKSK 1818
Query: 67 NMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLD 126
+T+A+L EA I ++++ + + + + A S Q D
Sbjct: 1819 -----FKSTIAAL------------------EAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 127 NEKTNFMYQVDTLKDMLLELEEQ-------LAESRRQYEEKNKEFEREKHAHSILQFQFA 179
+ + QV+ + M + +EQ + + +RQ EE +E +R LQ
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ---R 1912
Query: 180 EVKEALKQREEM 191
E+ EA + E M
Sbjct: 1913 ELDEATESNEAM 1924
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 64.3 bits (155), Expect = 2e-10
Identities = 99/454 (21%), Positives = 187/454 (41%), Gaps = 82/454 (18%)
Query: 15 LSPEAQKLAE-ARLAAKRAARAEAREIRMKELERQQKEVEERPEK------DFTEKGSRN 67
L+ E +K +L K + E+R+K+ E+ ++E+E+ K DF E+ + +
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA-D 1073
Query: 68 MPGLSAATLASLGGTSSRRGSG----DTSISIDTEA--SIREIKDSLAEVEEKYKKAMVS 121
+ A L + D I+ A IRE++ +++++E +
Sbjct: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLE---------------------LEEQLAESRRQYEEK 160
+ + +K + +++ LK L + L++ L E R +E +
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 161 NKEFEREKHAHSILQF-----QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
+E R+KHA ++ + QF K L + ++ LEK L E+ G+ + +
Sbjct: 1194 VQEM-RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH 1252
Query: 216 VGYQGPTKMTKEELNALKSTGD---GTLDIRLKKLVDERECLLEQIKKLKG--------- 263
+ ++ +EL + S G+ L+ ++ KL +E E + + + +G
Sbjct: 1253 KKKKLEAQV--QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 264 --------------QLEERQKIG---KLDNLRSEDDVLENGTDMHV---MDLQRDA---N 300
Q E RQK+ KL L E + L++ D + +L+R N
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+SD K KL + ALE+ R + ++ E D+L+ K +LQ+EL
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
D +L+ + LV LEK + LL+++
Sbjct: 1431 ---DLVVDLD-NQRQLVSNLEKKQRKFDQLLAEE 1460
Score = 61.6 bits (148), Expect = 1e-09
Identities = 79/373 (21%), Positives = 163/373 (43%), Gaps = 41/373 (10%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAA 74
L + Q+L +++ + ARAE + ++ + Q EVE +G A
Sbjct: 1257 LEAQVQEL-QSKCSDGERARAELND----KVHKLQNEVESVTGMLNEAEGKAIKLAKDVA 1311
Query: 75 TLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS-----------NA 123
+L+S + +T ++ +R++++ ++++ + M + N
Sbjct: 1312 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371
Query: 124 QLDNEKT---NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
QL + K +F V+ L++ ++++ +QYEEK +++ + + LQ + +
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD 1431
Query: 181 VKEALKQREEM---LEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGD 237
+ L + ++ LEK + +A S + + + ++E AL
Sbjct: 1432 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL----- 1486
Query: 238 GTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
+L L++ ++ +E L K LK ++E D + S+DDV G ++H ++ +
Sbjct: 1487 -SLARALEEALEAKEELERTNKMLKAEME--------DLVSSKDDV---GKNVHELEKSK 1534
Query: 298 DA-NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK-L 355
A Q+ ++K +L + E E+ A E +RLE + K E + DE EKR+ L
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 356 QRELRSALDKTEE 368
QR+L + E+
Sbjct: 1595 QRQLHEYETELED 1607
Score = 59.7 bits (143), Expect = 4e-09
Identities = 83/369 (22%), Positives = 160/369 (43%), Gaps = 65/369 (17%)
Query: 33 ARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASL-GGTSSRRGSGDT 91
AR E E + ++L+RQ E E E + R L+AA L G D+
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDE------RKQRALAAAAKKKLEGDLKDLELQADS 1635
Query: 92 SISIDTEA--SIREIKDSLAEVEEKYKKAMVSNAQL-----DNEKTNFMYQVDTLKDMLL 144
+I EA +R+++ + + + + + A S ++ +NEK + +L+ L+
Sbjct: 1636 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK-----KAKSLEADLM 1690
Query: 145 ELEEQLAESRRQYEEKNKEFER--EKHAHSI------------LQFQFAEVKEALKQREE 190
+L+E LA + R ++ + E E E+ A S+ L+ + A+++E L++ +
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 191 MLE----------KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
+E + L++E+AT E S N + + +EL + +G +
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELAT--ERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
+ K + E + Q+++ Q E R+K +L+ +D L ++
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKSLKQKDKKL------------KEIL 1855
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
Q+ D + K+A+ +E + ++V + K E AE+ + A +RKLQREL
Sbjct: 1856 LQVEDER-KMAEQYKE------QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 361 SALDKTEEL 369
A + E +
Sbjct: 1909 EATESNEAM 1917
Score = 58.9 bits (141), Expect = 8e-09
Identities = 100/444 (22%), Positives = 184/444 (41%), Gaps = 76/444 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGL 71
E + L + +L A+ AEA E+R++ ELE E+E R E++ ++G +
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEE-EDRGQQLQAER 945
Query: 72 S--AATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKA-------- 118
A + L + + ++ EA I++++D + ++++ K
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 119 -----MVSNAQLDNEKT-NFMYQVDTLKDMLLELEEQL---AESRRQYEEKNKEFERE-- 167
+ +N + EK N + + M+ ELE +L +SR++ E+ ++ E +
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 168 --KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA-----------TNGETSDTLN 214
+ LQ Q AE+K L ++EE L+ L+ EIA G SD
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 215 NVGYQGPTKMTK--------EELNALKSTGDGTLDI----------RLKKLVDERECLLE 256
++ + + EEL ALK+ + TLD R +++ ++ L E
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 257 QIKKLKGQLEE-RQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQI-----SDLKFKL 310
+ + + Q++E RQK + ++ +++ E D N+Q +DL +L
Sbjct: 1186 ETRSHEAQVQEMRQK-----HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1240
Query: 311 AKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
Q +E +LE+QV +S + E+ EL + KLQ E+ S E E
Sbjct: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 371 VSNGHLVKRLEKMKANRSALLSQQ 394
G +K + + + S L Q
Sbjct: 1301 ---GKAIKLAKDVASLSSQLQDTQ 1321
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/301 (22%), Positives = 130/301 (43%), Gaps = 43/301 (14%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE---QLAESR 154
E +++ K+ + E + K+ ++QL EK Q+ ++ E EE +LA +
Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 155 RQYEEKNKEFE----REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 210
++ EE E E E+ LQ + ++ + + EE LE+ E A +
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE-------EEAARQKLQ 970
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL-EERQ 269
L V + K ++E+ + D + KL ER+ L E+I L L EE +
Sbjct: 971 --LEKVTAEAKIKKLEDEILVM--------DDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
Query: 270 KIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLES 329
K L L+++ + + IS+L+ +L K E+ LE+ +LE
Sbjct: 1021 KAKNLTKLKNKHESM------------------ISELEVRLKKEEKSRQELEKLKRKLEG 1062
Query: 330 QVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
S + + + ELK + K + EL++AL + ++ + +K++ +++ + S
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD 1122
Query: 390 L 390
L
Sbjct: 1123 L 1123
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/293 (23%), Positives = 126/293 (43%), Gaps = 43/293 (14%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
D E + E+ D + +++ + + + + + V +L L + +E L E R
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
Q + + + + + LQ Q E EA ++ LE+H LN +++ +
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEA----KQNLERHISTLNIQLSDS--------- 1376
Query: 216 VGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLD 275
K++L ST ++ L + ++ ++I+ L Q EE K D
Sbjct: 1377 ----------KKKLQDFAST--------VEALEEGKKRFQKEIENLTQQYEE--KAAAYD 1416
Query: 276 NLRSEDDVLENGTDMHVMDLQRDANRQ-ISDLKFKLAKSEQEITALEQNVIRLESQVSRY 334
L + L+ D V+DL D RQ +S+L+ K K +Q + A E+N+ S+Y
Sbjct: 1417 KLEKTKNRLQQELDDLVVDL--DNQRQLVSNLEKKQRKFDQ-LLAEEKNIS------SKY 1467
Query: 335 KSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANR 387
+ AE E + + L R L AL+ EELE +N L +E + +++
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Score = 54.3 bits (129), Expect = 2e-07
Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 26/380 (6%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + ++ + A AEARE K L + E K+
Sbjct: 1442 LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ ++ + ++S + S E + E+K L E+E++ +
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA-LETQMEEMKTQLEELEDELQATED 1560
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
+ +L+ N + L +EQ E RRQ + + E+E E + A
Sbjct: 1561 AKLRLE---VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
K+ L+ + LE L ++ A G Q K + EL +++ D +
Sbjct: 1618 AKKKLEGDLKDLE-----LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD-EI 1671
Query: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
K+ + + L + +L+ L ++ K +L E+ E + + + +D
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1731
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEK-------- 352
R+ L+ ++A+ E+E LE+ +E+ R + A + AE++ +EL E+
Sbjct: 1732 RR---LEARIAQLEEE---LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 353 --RKLQRELRSALDKTEELE 370
++L+R+ + K E+E
Sbjct: 1786 ARQQLERQNKELRSKLHEME 1805
Score = 52.4 bits (124), Expect = 7e-07
Identities = 62/284 (21%), Positives = 122/284 (42%), Gaps = 44/284 (15%)
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHS-------ILQFQFAEV 181
K + QV ++ + E++L +++ + ++ E + + HS +LQ Q
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLD 241
E + EEM + L + ++ ++ +EE
Sbjct: 900 TELYAEAEEMRVR-----------LAAKKQELEEILHEMEARLEEEE------------- 935
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEE----RQKIGKLDNLRSEDDVLENGTDMHVMDLQR 297
R ++L ER+ + +Q+ L+ QLEE RQK+ +L+ + +E + + ++ VMD Q
Sbjct: 936 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL-QLEKVTAEAKIKKLEDEILVMDDQN 994
Query: 298 D--------ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELK 349
+ +ISDL LA+ E++ L + + ES +S + + EK EL+
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 350 AEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KRKL+ + ++ +L+ L +L K + A L++
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Score = 50.4 bits (119), Expect = 3e-06
Identities = 75/406 (18%), Positives = 167/406 (41%), Gaps = 42/406 (10%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
++++ LS + Q E R + ++R E ER + + E + + R++
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI 1366
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDT-EASIREIKDSLAEVEEKYKKAMVSNAQLDN 127
L+ + S++ D + +++ E + + + + ++Y++ + +L+
Sbjct: 1367 STLNIQL------SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Query: 128 EKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQ 187
K ++D D++++L+ Q + E+K ++F++ + ++A+ ++ +
Sbjct: 1421 TKNRLQQELD---DLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 1476
Query: 188 REEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKL 247
E + L + E + L KM K E+ L S+ D + + +L
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTN-----KMLKAEMEDLVSSKDD-VGKNVHEL 1530
Query: 248 VDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDV-LENGTDMHVM------DLQ---- 296
+ L Q++++K QLEE + D L++ +D L +M + DLQ
Sbjct: 1531 EKSKRALETQMEEMKTQLEELE-----DELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 297 ------RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
R RQ+ + + +L ++ +LE + + A++A K +E
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 351 EKRKLQRELRSALDKTEELEVSNGHL---VKRLEKMKANRSALLSQ 393
+ RKLQ +++ + E+ S + K EK + A L Q
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1691
Score = 33.5 bits (75), Expect = 0.34
Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 35/192 (18%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSR 66
A S + + +A++L+ LA +R+ A+ E ++LERQ KE+ + + S+
Sbjct: 1754 AMSDRVRKATQQAEQLSN-ELATERST-AQKNESARQQLERQNKELRSKLHEMEGAVKSK 1811
Query: 67 NMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLD 126
+T+A+L EA I ++++ + + + + A S Q D
Sbjct: 1812 -----FKSTIAAL------------------EAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 127 NEKTNFMYQVDTLKDMLLELEEQ-------LAESRRQYEEKNKEFEREKHAHSILQFQFA 179
+ + QV+ + M + +EQ + + +RQ EE +E +R LQ
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ---R 1905
Query: 180 EVKEALKQREEM 191
E+ EA + E M
Sbjct: 1906 ELDEATESNEAM 1917
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 63.9 bits (154), Expect = 2e-10
Identities = 88/407 (21%), Positives = 179/407 (43%), Gaps = 37/407 (9%)
Query: 8 QSREIDCLSPEAQKLAEARLAAKR-AARAEAREIRMKELERQQKEVEERPEKDFTEKG-- 64
++R + L EA+ AEA R AAR + E+ + ELE + E EE + TEK
Sbjct: 914 RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 973
Query: 65 SRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQ 124
+++ L A A G + + TEA +++ ++ L +E++ K
Sbjct: 974 QQHIQELEAHLEAEEGARQKLQLE-----KVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1028
Query: 125 LDNEKTNFMYQ-------VDTLKDMLLELEEQLA--ESRRQYEEKNK-EFEREKHAHSIL 174
L++ F Q V +L + L+ E +A E R + EEK + E E+ K L
Sbjct: 1029 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRR---L 1085
Query: 175 QFQFAEVKEALKQREEMLEK-HGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK 233
+ +E++E + ++++ E+ + E + + G + + E A
Sbjct: 1086 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAAL 1145
Query: 234 STGDGTLD---IRLKKLVDERECLLEQIKKLKGQLEER-QKIGKLDNLRSEDD------- 282
+ L+ + K +R L E+++ L+G+LE+ LRS+ +
Sbjct: 1146 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1205
Query: 283 -VLENGTDMH---VMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAA 338
LE T +H V +L++ + + +L +L ++ + A E+ + LE++VS ++
Sbjct: 1206 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAEL 1265
Query: 339 ENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKA 385
+ + E + +R+L+ +L+ + + E + ++L++ +A
Sbjct: 1266 SSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 1312
Score = 62.8 bits (151), Expect = 5e-10
Identities = 83/368 (22%), Positives = 159/368 (43%), Gaps = 39/368 (10%)
Query: 34 RAEAREIRMKELERQQKEVE-ERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 92
R EA E R ++L +Q ++ E ER E+ R L+ A L G + S
Sbjct: 1608 RDEAGEERRRQLAKQLRDAEVERDEE-------RKQRTLAVAARKKLEGELEELKAQMAS 1660
Query: 93 ISIDTEASIREIKDSLAEVEEKYKKA---MVSNAQLDNEKTNFMYQVDTLKDMLLELEEQ 149
E ++++++ A+++E +++ S ++ ++ ++ L+ +L L+E+
Sbjct: 1661 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
Query: 150 LAES---RRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 206
LA S RRQ ++ E E ++ + E K L+ R LE+ L E + +
Sbjct: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEE---LEEEQSNS 1777
Query: 207 GETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE 266
+D + Q + T EL+A +S K R+ L QI++L+G+L
Sbjct: 1778 ELLNDRYRKLLLQVESLTT--ELSAERSFS--------AKAESGRQQLERQIQELRGRLG 1827
Query: 267 E---------RQKIGKLDN-LRSEDDVLENGTDMHVMD--LQRDANRQISDLKFKLAKSE 314
E + I L++ L ++ LE T ++ L R A +++ ++ ++ +
Sbjct: 1828 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1887
Query: 315 QEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNG 374
+ L + + +V + K E AE+ +A +R+LQREL + E +
Sbjct: 1888 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1947
Query: 375 HLVKRLEK 382
L RL +
Sbjct: 1948 TLRNRLRR 1955
Score = 55.5 bits (132), Expect = 8e-08
Identities = 63/267 (23%), Positives = 113/267 (42%), Gaps = 35/267 (13%)
Query: 123 AQLDNEKTNFMYQVDTLKDMLLELEE---QLAESRRQYEEKNKEFEREKHAHSILQFQFA 179
AQL+ E+ Q+ ++ E EE +LA +++ E E E Q
Sbjct: 908 AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQ 967
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 239
K+ L+Q + LE H E L V + K +E+L L+
Sbjct: 968 TEKKRLQQHIQELEAH-----LEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS-- 1020
Query: 240 LDIRLKKLVDERECLLEQIKKLKGQL-EERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD 298
KL ER+ L +++ + Q EE +K+ L+ LR L+ +
Sbjct: 1021 ------KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLR----------------LKYE 1058
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
A I+D++ +L K E+ LE+ RL+ + S + ++ +EL+A+ + + E
Sbjct: 1059 AT--IADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEE 1116
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKA 385
L++AL + E+ + L+K L + +A
Sbjct: 1117 LQAALARAEDEGGARAQLLKSLREAQA 1143
Score = 47.4 bits (111), Expect = 2e-05
Identities = 94/445 (21%), Positives = 178/445 (40%), Gaps = 98/445 (22%)
Query: 24 EARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
E RL + R E +++ + EL+ Q E ++R E+ + G R L AA
Sbjct: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG-RKEEELQAALA- 1122
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD 137
R + S+RE + +LAE +E + V+ + + ++ + +++
Sbjct: 1123 --------RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELE 1174
Query: 138 TLK--------------DMLLELEEQLAESRRQYEEKNKEFE------REKHAHSILQFQ 177
L+ ++ + E+++ E ++ EE+ + E R++H ++ +
Sbjct: 1175 ALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQAL--GE 1232
Query: 178 FAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK---S 234
AE E ++ + EK + L +E++ +L +G + + EL +
Sbjct: 1233 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1292
Query: 235 TGDG-----------------------------TLDIRLKKLVDERECLLEQIKKLKGQL 265
GDG + IRL K + E L ++L Q
Sbjct: 1293 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL-QE 1351
Query: 266 EERQKI---GKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLA----KSEQEIT 318
E R K+ ++ + +E L + +R A R++ + +L+ + E+E
Sbjct: 1352 ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARER-AGRELQTAQAQLSEWRRRQEEEAG 1410
Query: 319 ALEQNVIRLESQVSRYKSAAEN-------AEKIE--DELKAEKRKLQRELRSALDKTEEL 369
ALE + +R ++A E AEK E D L+ +R+LQ+EL D T +L
Sbjct: 1411 ALE------AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDL 1461
Query: 370 EVSNGHLVKRLEKMKANRSALLSQQ 394
E LV LEK + LL+++
Sbjct: 1462 E-QQRQLVSTLEKKQRKFDQLLAEE 1485
Score = 46.6 bits (109), Expect = 4e-05
Identities = 78/392 (19%), Positives = 152/392 (38%), Gaps = 80/392 (20%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + + + A AE RE + L + EE+ ++
Sbjct: 1467 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREE 1526
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ +R + A L+S D S+ E++ + E+
Sbjct: 1527 LERQNRALRAELEALLSSKD---------------DVGKSVHELERACRVAEQAANDLRA 1571
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFA- 179
+L++E T +D L LE + + Q+E ++ + A + Q A
Sbjct: 1572 QVTELEDELT-------AAEDAKLRLEVTVQALKTQHE---RDLQGRDEAGEERRRQLAK 1621
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNA-LKSTGDG 238
++++A +R+E ++ + + + GE EEL A + S G G
Sbjct: 1622 QLRDAEVERDEERKQRTLAVAARKKLEGEL-----------------EELKAQMASAGQG 1664
Query: 239 TLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD 298
+E ++Q++K++ Q++E + +V E T + Q
Sbjct: 1665 ------------KEEAVKQLRKMQAQMKELWR-----------EVEETRTSREEIFSQ-- 1699
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
NR+ SE+ + LE V+RL+ +++ A A++ DE+ E
Sbjct: 1700 -NRE----------SEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1748
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKANRSAL 390
+ L++ +LE G L + LE+ ++N L
Sbjct: 1749 KAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1780
Score = 42.4 bits (98), Expect = 7e-04
Identities = 96/460 (20%), Positives = 182/460 (39%), Gaps = 95/460 (20%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVE------ERPEKDFTEKGSRNM 68
L E +L A L++ + AR E + R + LE Q +EV+ ER + EK R
Sbjct: 1254 LEAEVSEL-RAELSSLQTARQEGEQ-RRRRLELQLQEVQGRAGDGERARAEAAEKLQR-- 1309
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKAMVSNAQ- 124
+ A L ++ G + S +S + TEA + + ++ L E E + K A+ S +
Sbjct: 1310 ---AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE-ETRAKLALGSRVRA 1365
Query: 125 LDNEKTNFMYQVDTLKDM-------LLELEEQLAESRRQYEEKNKEFE----------RE 167
++ E Q++ L + QL+E RR+ EE+ E RE
Sbjct: 1366 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1425
Query: 168 KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKE 227
A + + E + L++ L++ ++ + TL + + +E
Sbjct: 1426 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1485
Query: 228 ELNALKSTGDGTLDIRLKKLVDEREC-------LLEQIKKLKGQLEERQKIGKLDN---L 277
+ L++ + R + ERE LE+ ++ + +LE + + + + L
Sbjct: 1486 KAAVLRAVEERE---RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1542
Query: 278 RSEDDVLENGTDMHVMDLQ-RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKS 336
S+DDV G +H ++ R A + +DL+ ++ + E E+TA E +RLE V K+
Sbjct: 1543 SSKDDV---GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1599
Query: 337 AAEN----------------------------------------AEKIE---DELKAEKR 353
E +K+E +ELKA+
Sbjct: 1600 QHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA 1659
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+ A+ + +++ L + +E+ + +R + SQ
Sbjct: 1660 SAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1699
Score = 40.0 bits (92), Expect = 0.004
Identities = 76/380 (20%), Positives = 149/380 (39%), Gaps = 40/380 (10%)
Query: 10 REIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMP 69
RE EAQ+ E+ A+ A + R++ +ELE + E+E+ + ++ R+
Sbjct: 1139 REAQAALAEAQEDLESERVARTKAEKQRRDLG-EELEALRGELEDTLDSTNAQQELRSKR 1197
Query: 70 GLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKD----SLAEVEEKYKKAMVSNAQL 125
L + +T I EA+++E++ +L E+ E+ ++A
Sbjct: 1198 EQEVTEL-------KKTLEEETRIH---EAAVQELRQRHGQALGELAEQLEQARRGKGAW 1247
Query: 126 DNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEAL 185
+ + +V L+ L L+ E ++ + + + + AE E L
Sbjct: 1248 EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKL 1307
Query: 186 KQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNALKSTGDGT---- 239
++ + LE LN + S L++ Q ++ +EE A + G
Sbjct: 1308 QRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAME 1367
Query: 240 -----LDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMD 294
L +L++ RE +++ + QL E ++ E LE G +
Sbjct: 1368 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRR-----RQEEEAGALEAGEEA---- 1418
Query: 295 LQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK 354
+R A R+ L +LA+ + + LE+ RL+ ++ E ++ L+ ++RK
Sbjct: 1419 -RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRK 1477
Query: 355 ----LQRELRSALDKTEELE 370
L E + L EE E
Sbjct: 1478 FDQLLAEEKAAVLRAVEERE 1497
Score = 35.0 bits (79), Expect = 0.12
Identities = 89/408 (21%), Positives = 168/408 (41%), Gaps = 71/408 (17%)
Query: 19 AQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
A + A L + A ARE +EL+ Q ++ E + E G+
Sbjct: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGA-----------LE 1413
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
G + RR + + A E D L + ++ + +A +D E+ + V T
Sbjct: 1414 AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQEL-DDATMDLEQQRQL--VST 1470
Query: 139 LKDMLLELEEQLAESR----RQYEEKNKEF----EREKHAHSILQFQFAEVKEALKQREE 190
L+ + ++ LAE + R EE+ + ERE A S+ + ++E + REE
Sbjct: 1471 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR----ALEEEQEAREE 1526
Query: 191 MLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNALKSTGDGTLDIRLKKLV 248
LE+ L +E+ + D + ++ ++ ++ N L++ L+ L
Sbjct: 1527 -LERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT-ELEDELTAAE 1584
Query: 249 DERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANR------- 301
D + L ++ LK Q ER G+ + E+ + + +++RD R
Sbjct: 1585 DAKLRLEVTVQALKTQ-HERDLQGRDE--AGEERRRQLAKQLRDAEVERDEERKQRTLAV 1641
Query: 302 --------QISDLKFKLAKSEQ-------EITALEQNVIRL-----ESQVSRYKSAAEN- 340
++ +LK ++A + Q ++ ++ + L E++ SR + ++N
Sbjct: 1642 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1701
Query: 341 -AEKIEDELKAEKRKLQREL-------RSALDKTEEL--EVSNGHLVK 378
+EK L+AE +LQ EL R A +E+ EV+NG+L K
Sbjct: 1702 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSK 1749
Score = 33.9 bits (76), Expect = 0.26
Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Query: 270 KIGKLDNLRSEDDVLENGTD--MHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRL 327
K+ L + +D+VL+ V +LQ+ + R++ +L+ ++A+ LE+ RL
Sbjct: 865 KVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEERARL 917
Query: 328 ESQVSRYKSAAENAEKIEDELKAEKRKLQ---RELRSALDKTEE----LEVSNGHLVKRL 380
Q+ AE+ L A K++L+ EL + + + EE ++ L + +
Sbjct: 918 AEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHI 977
Query: 381 EKMKANRSA 389
++++A+ A
Sbjct: 978 QELEAHLEA 986
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 63.9 bits (154), Expect = 2e-10
Identities = 88/407 (21%), Positives = 179/407 (43%), Gaps = 37/407 (9%)
Query: 8 QSREIDCLSPEAQKLAEARLAAKR-AARAEAREIRMKELERQQKEVEERPEKDFTEKG-- 64
++R + L EA+ AEA R AAR + E+ + ELE + E EE + TEK
Sbjct: 906 RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 965
Query: 65 SRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQ 124
+++ L A A G + + TEA +++ ++ L +E++ K
Sbjct: 966 QQHIQELEAHLEAEEGARQKLQLE-----KVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1020
Query: 125 LDNEKTNFMYQ-------VDTLKDMLLELEEQLA--ESRRQYEEKNK-EFEREKHAHSIL 174
L++ F Q V +L + L+ E +A E R + EEK + E E+ K L
Sbjct: 1021 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRR---L 1077
Query: 175 QFQFAEVKEALKQREEMLEK-HGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK 233
+ +E++E + ++++ E+ + E + + G + + E A
Sbjct: 1078 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAAL 1137
Query: 234 STGDGTLD---IRLKKLVDERECLLEQIKKLKGQLEER-QKIGKLDNLRSEDD------- 282
+ L+ + K +R L E+++ L+G+LE+ LRS+ +
Sbjct: 1138 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1197
Query: 283 -VLENGTDMH---VMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAA 338
LE T +H V +L++ + + +L +L ++ + A E+ + LE++VS ++
Sbjct: 1198 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAEL 1257
Query: 339 ENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKA 385
+ + E + +R+L+ +L+ + + E + ++L++ +A
Sbjct: 1258 SSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 1304
Score = 62.8 bits (151), Expect = 5e-10
Identities = 83/368 (22%), Positives = 159/368 (43%), Gaps = 39/368 (10%)
Query: 34 RAEAREIRMKELERQQKEVE-ERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 92
R EA E R ++L +Q ++ E ER E+ R L+ A L G + S
Sbjct: 1600 RDEAGEERRRQLAKQLRDAEVERDEE-------RKQRTLAVAARKKLEGELEELKAQMAS 1652
Query: 93 ISIDTEASIREIKDSLAEVEEKYKKA---MVSNAQLDNEKTNFMYQVDTLKDMLLELEEQ 149
E ++++++ A+++E +++ S ++ ++ ++ L+ +L L+E+
Sbjct: 1653 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712
Query: 150 LAES---RRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 206
LA S RRQ ++ E E ++ + E K L+ R LE+ L E + +
Sbjct: 1713 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEE---LEEEQSNS 1769
Query: 207 GETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE 266
+D + Q + T EL+A +S K R+ L QI++L+G+L
Sbjct: 1770 ELLNDRYRKLLLQVESLTT--ELSAERSFS--------AKAESGRQQLERQIQELRGRLG 1819
Query: 267 E---------RQKIGKLDN-LRSEDDVLENGTDMHVMD--LQRDANRQISDLKFKLAKSE 314
E + I L++ L ++ LE T ++ L R A +++ ++ ++ +
Sbjct: 1820 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1879
Query: 315 QEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNG 374
+ L + + +V + K E AE+ +A +R+LQREL + E +
Sbjct: 1880 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1939
Query: 375 HLVKRLEK 382
L RL +
Sbjct: 1940 TLRNRLRR 1947
Score = 55.5 bits (132), Expect = 8e-08
Identities = 63/267 (23%), Positives = 113/267 (42%), Gaps = 35/267 (13%)
Query: 123 AQLDNEKTNFMYQVDTLKDMLLELEE---QLAESRRQYEEKNKEFEREKHAHSILQFQFA 179
AQL+ E+ Q+ ++ E EE +LA +++ E E E Q
Sbjct: 900 AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQ 959
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 239
K+ L+Q + LE H E L V + K +E+L L+
Sbjct: 960 TEKKRLQQHIQELEAH-----LEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS-- 1012
Query: 240 LDIRLKKLVDERECLLEQIKKLKGQL-EERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD 298
KL ER+ L +++ + Q EE +K+ L+ LR L+ +
Sbjct: 1013 ------KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLR----------------LKYE 1050
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
A I+D++ +L K E+ LE+ RL+ + S + ++ +EL+A+ + + E
Sbjct: 1051 AT--IADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEE 1108
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKA 385
L++AL + E+ + L+K L + +A
Sbjct: 1109 LQAALARAEDEGGARAQLLKSLREAQA 1135
Score = 47.4 bits (111), Expect = 2e-05
Identities = 94/445 (21%), Positives = 178/445 (40%), Gaps = 98/445 (22%)
Query: 24 EARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
E RL + R E +++ + EL+ Q E ++R E+ + G R L AA
Sbjct: 1057 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG-RKEEELQAALA- 1114
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD 137
R + S+RE + +LAE +E + V+ + + ++ + +++
Sbjct: 1115 --------RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELE 1166
Query: 138 TLK--------------DMLLELEEQLAESRRQYEEKNKEFE------REKHAHSILQFQ 177
L+ ++ + E+++ E ++ EE+ + E R++H ++ +
Sbjct: 1167 ALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQAL--GE 1224
Query: 178 FAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK---S 234
AE E ++ + EK + L +E++ +L +G + + EL +
Sbjct: 1225 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1284
Query: 235 TGDG-----------------------------TLDIRLKKLVDERECLLEQIKKLKGQL 265
GDG + IRL K + E L ++L Q
Sbjct: 1285 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL-QE 1343
Query: 266 EERQKI---GKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLA----KSEQEIT 318
E R K+ ++ + +E L + +R A R++ + +L+ + E+E
Sbjct: 1344 ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARER-AGRELQTAQAQLSEWRRRQEEEAG 1402
Query: 319 ALEQNVIRLESQVSRYKSAAEN-------AEKIE--DELKAEKRKLQRELRSALDKTEEL 369
ALE + +R ++A E AEK E D L+ +R+LQ+EL D T +L
Sbjct: 1403 ALE------AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDL 1453
Query: 370 EVSNGHLVKRLEKMKANRSALLSQQ 394
E LV LEK + LL+++
Sbjct: 1454 E-QQRQLVSTLEKKQRKFDQLLAEE 1477
Score = 46.6 bits (109), Expect = 4e-05
Identities = 78/392 (19%), Positives = 152/392 (38%), Gaps = 80/392 (20%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + + + A AE RE + L + EE+ ++
Sbjct: 1459 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREE 1518
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ +R + A L+S D S+ E++ + E+
Sbjct: 1519 LERQNRALRAELEALLSSKD---------------DVGKSVHELERACRVAEQAANDLRA 1563
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFA- 179
+L++E T +D L LE + + Q+E ++ + A + Q A
Sbjct: 1564 QVTELEDELT-------AAEDAKLRLEVTVQALKTQHE---RDLQGRDEAGEERRRQLAK 1613
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNA-LKSTGDG 238
++++A +R+E ++ + + + GE EEL A + S G G
Sbjct: 1614 QLRDAEVERDEERKQRTLAVAARKKLEGEL-----------------EELKAQMASAGQG 1656
Query: 239 TLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD 298
+E ++Q++K++ Q++E + +V E T + Q
Sbjct: 1657 ------------KEEAVKQLRKMQAQMKELWR-----------EVEETRTSREEIFSQ-- 1691
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
NR+ SE+ + LE V+RL+ +++ A A++ DE+ E
Sbjct: 1692 -NRE----------SEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1740
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKANRSAL 390
+ L++ +LE G L + LE+ ++N L
Sbjct: 1741 KAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1772
Score = 42.4 bits (98), Expect = 7e-04
Identities = 96/460 (20%), Positives = 182/460 (39%), Gaps = 95/460 (20%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVE------ERPEKDFTEKGSRNM 68
L E +L A L++ + AR E + R + LE Q +EV+ ER + EK R
Sbjct: 1246 LEAEVSEL-RAELSSLQTARQEGEQ-RRRRLELQLQEVQGRAGDGERARAEAAEKLQR-- 1301
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKAMVSNAQ- 124
+ A L ++ G + S +S + TEA + + ++ L E E + K A+ S +
Sbjct: 1302 ---AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE-ETRAKLALGSRVRA 1357
Query: 125 LDNEKTNFMYQVDTLKDM-------LLELEEQLAESRRQYEEKNKEFE----------RE 167
++ E Q++ L + QL+E RR+ EE+ E RE
Sbjct: 1358 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1417
Query: 168 KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKE 227
A + + E + L++ L++ ++ + TL + + +E
Sbjct: 1418 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477
Query: 228 ELNALKSTGDGTLDIRLKKLVDEREC-------LLEQIKKLKGQLEERQKIGKLDN---L 277
+ L++ + R + ERE LE+ ++ + +LE + + + + L
Sbjct: 1478 KAAVLRAVEERE---RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1534
Query: 278 RSEDDVLENGTDMHVMDLQ-RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKS 336
S+DDV G +H ++ R A + +DL+ ++ + E E+TA E +RLE V K+
Sbjct: 1535 SSKDDV---GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1591
Query: 337 AAEN----------------------------------------AEKIE---DELKAEKR 353
E +K+E +ELKA+
Sbjct: 1592 QHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA 1651
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+ A+ + +++ L + +E+ + +R + SQ
Sbjct: 1652 SAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1691
Score = 40.0 bits (92), Expect = 0.004
Identities = 76/380 (20%), Positives = 149/380 (39%), Gaps = 40/380 (10%)
Query: 10 REIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMP 69
RE EAQ+ E+ A+ A + R++ +ELE + E+E+ + ++ R+
Sbjct: 1131 REAQAALAEAQEDLESERVARTKAEKQRRDLG-EELEALRGELEDTLDSTNAQQELRSKR 1189
Query: 70 GLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKD----SLAEVEEKYKKAMVSNAQL 125
L + +T I EA+++E++ +L E+ E+ ++A
Sbjct: 1190 EQEVTEL-------KKTLEEETRIH---EAAVQELRQRHGQALGELAEQLEQARRGKGAW 1239
Query: 126 DNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEAL 185
+ + +V L+ L L+ E ++ + + + + AE E L
Sbjct: 1240 EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKL 1299
Query: 186 KQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNALKSTGDGT---- 239
++ + LE LN + S L++ Q ++ +EE A + G
Sbjct: 1300 QRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAME 1359
Query: 240 -----LDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMD 294
L +L++ RE +++ + QL E ++ E LE G +
Sbjct: 1360 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRR-----RQEEEAGALEAGEEA---- 1410
Query: 295 LQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK 354
+R A R+ L +LA+ + + LE+ RL+ ++ E ++ L+ ++RK
Sbjct: 1411 -RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRK 1469
Query: 355 ----LQRELRSALDKTEELE 370
L E + L EE E
Sbjct: 1470 FDQLLAEEKAAVLRAVEERE 1489
Score = 35.0 bits (79), Expect = 0.12
Identities = 89/408 (21%), Positives = 168/408 (41%), Gaps = 71/408 (17%)
Query: 19 AQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
A + A L + A ARE +EL+ Q ++ E + E G+
Sbjct: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGA-----------LE 1405
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
G + RR + + A E D L + ++ + +A +D E+ + V T
Sbjct: 1406 AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQEL-DDATMDLEQQRQL--VST 1462
Query: 139 LKDMLLELEEQLAESR----RQYEEKNKEF----EREKHAHSILQFQFAEVKEALKQREE 190
L+ + ++ LAE + R EE+ + ERE A S+ + ++E + REE
Sbjct: 1463 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR----ALEEEQEAREE 1518
Query: 191 MLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNALKSTGDGTLDIRLKKLV 248
LE+ L +E+ + D + ++ ++ ++ N L++ L+ L
Sbjct: 1519 -LERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT-ELEDELTAAE 1576
Query: 249 DERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANR------- 301
D + L ++ LK Q ER G+ + E+ + + +++RD R
Sbjct: 1577 DAKLRLEVTVQALKTQ-HERDLQGRDE--AGEERRRQLAKQLRDAEVERDEERKQRTLAV 1633
Query: 302 --------QISDLKFKLAKSEQ-------EITALEQNVIRL-----ESQVSRYKSAAEN- 340
++ +LK ++A + Q ++ ++ + L E++ SR + ++N
Sbjct: 1634 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1693
Query: 341 -AEKIEDELKAEKRKLQREL-------RSALDKTEEL--EVSNGHLVK 378
+EK L+AE +LQ EL R A +E+ EV+NG+L K
Sbjct: 1694 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSK 1741
Score = 33.9 bits (76), Expect = 0.26
Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Query: 270 KIGKLDNLRSEDDVLENGTD--MHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRL 327
K+ L + +D+VL+ V +LQ+ + R++ +L+ ++A+ LE+ RL
Sbjct: 857 KVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEERARL 909
Query: 328 ESQVSRYKSAAENAEKIEDELKAEKRKLQ---RELRSALDKTEE----LEVSNGHLVKRL 380
Q+ AE+ L A K++L+ EL + + + EE ++ L + +
Sbjct: 910 AEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHI 969
Query: 381 EKMKANRSA 389
++++A+ A
Sbjct: 970 QELEAHLEA 978
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 63.9 bits (154), Expect = 2e-10
Identities = 88/407 (21%), Positives = 179/407 (43%), Gaps = 37/407 (9%)
Query: 8 QSREIDCLSPEAQKLAEARLAAKR-AARAEAREIRMKELERQQKEVEERPEKDFTEKG-- 64
++R + L EA+ AEA R AAR + E+ + ELE + E EE + TEK
Sbjct: 947 RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006
Query: 65 SRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQ 124
+++ L A A G + + TEA +++ ++ L +E++ K
Sbjct: 1007 QQHIQELEAHLEAEEGARQKLQLE-----KVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1061
Query: 125 LDNEKTNFMYQ-------VDTLKDMLLELEEQLA--ESRRQYEEKNK-EFEREKHAHSIL 174
L++ F Q V +L + L+ E +A E R + EEK + E E+ K L
Sbjct: 1062 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRR---L 1118
Query: 175 QFQFAEVKEALKQREEMLEK-HGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK 233
+ +E++E + ++++ E+ + E + + G + + E A
Sbjct: 1119 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAAL 1178
Query: 234 STGDGTLD---IRLKKLVDERECLLEQIKKLKGQLEER-QKIGKLDNLRSEDD------- 282
+ L+ + K +R L E+++ L+G+LE+ LRS+ +
Sbjct: 1179 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238
Query: 283 -VLENGTDMH---VMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAA 338
LE T +H V +L++ + + +L +L ++ + A E+ + LE++VS ++
Sbjct: 1239 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAEL 1298
Query: 339 ENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKA 385
+ + E + +R+L+ +L+ + + E + ++L++ +A
Sbjct: 1299 SSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 1345
Score = 62.8 bits (151), Expect = 5e-10
Identities = 83/368 (22%), Positives = 159/368 (43%), Gaps = 39/368 (10%)
Query: 34 RAEAREIRMKELERQQKEVE-ERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 92
R EA E R ++L +Q ++ E ER E+ R L+ A L G + S
Sbjct: 1641 RDEAGEERRRQLAKQLRDAEVERDEE-------RKQRTLAVAARKKLEGELEELKAQMAS 1693
Query: 93 ISIDTEASIREIKDSLAEVEEKYKKA---MVSNAQLDNEKTNFMYQVDTLKDMLLELEEQ 149
E ++++++ A+++E +++ S ++ ++ ++ L+ +L L+E+
Sbjct: 1694 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
Query: 150 LAES---RRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 206
LA S RRQ ++ E E ++ + E K L+ R LE+ L E + +
Sbjct: 1754 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEE---LEEEQSNS 1810
Query: 207 GETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE 266
+D + Q + T EL+A +S K R+ L QI++L+G+L
Sbjct: 1811 ELLNDRYRKLLLQVESLTT--ELSAERSFS--------AKAESGRQQLERQIQELRGRLG 1860
Query: 267 E---------RQKIGKLDN-LRSEDDVLENGTDMHVMD--LQRDANRQISDLKFKLAKSE 314
E + I L++ L ++ LE T ++ L R A +++ ++ ++ +
Sbjct: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
Query: 315 QEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNG 374
+ L + + +V + K E AE+ +A +R+LQREL + E +
Sbjct: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
Query: 375 HLVKRLEK 382
L RL +
Sbjct: 1981 TLRNRLRR 1988
Score = 55.5 bits (132), Expect = 8e-08
Identities = 63/267 (23%), Positives = 113/267 (42%), Gaps = 35/267 (13%)
Query: 123 AQLDNEKTNFMYQVDTLKDMLLELEE---QLAESRRQYEEKNKEFEREKHAHSILQFQFA 179
AQL+ E+ Q+ ++ E EE +LA +++ E E E Q
Sbjct: 941 AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQ 1000
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 239
K+ L+Q + LE H E L V + K +E+L L+
Sbjct: 1001 TEKKRLQQHIQELEAH-----LEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS-- 1053
Query: 240 LDIRLKKLVDERECLLEQIKKLKGQL-EERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD 298
KL ER+ L +++ + Q EE +K+ L+ LR L+ +
Sbjct: 1054 ------KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLR----------------LKYE 1091
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
A I+D++ +L K E+ LE+ RL+ + S + ++ +EL+A+ + + E
Sbjct: 1092 AT--IADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEE 1149
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKA 385
L++AL + E+ + L+K L + +A
Sbjct: 1150 LQAALARAEDEGGARAQLLKSLREAQA 1176
Score = 47.4 bits (111), Expect = 2e-05
Identities = 94/445 (21%), Positives = 178/445 (40%), Gaps = 98/445 (22%)
Query: 24 EARLAAKRAARAEAREIRMK------ELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
E RL + R E +++ + EL+ Q E ++R E+ + G R L AA
Sbjct: 1098 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG-RKEEELQAALA- 1155
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD 137
R + S+RE + +LAE +E + V+ + + ++ + +++
Sbjct: 1156 --------RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELE 1207
Query: 138 TLK--------------DMLLELEEQLAESRRQYEEKNKEFE------REKHAHSILQFQ 177
L+ ++ + E+++ E ++ EE+ + E R++H ++ +
Sbjct: 1208 ALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQAL--GE 1265
Query: 178 FAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK---S 234
AE E ++ + EK + L +E++ +L +G + + EL +
Sbjct: 1266 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1325
Query: 235 TGDG-----------------------------TLDIRLKKLVDERECLLEQIKKLKGQL 265
GDG + IRL K + E L ++L Q
Sbjct: 1326 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL-QE 1384
Query: 266 EERQKI---GKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLA----KSEQEIT 318
E R K+ ++ + +E L + +R A R++ + +L+ + E+E
Sbjct: 1385 ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARER-AGRELQTAQAQLSEWRRRQEEEAG 1443
Query: 319 ALEQNVIRLESQVSRYKSAAEN-------AEKIE--DELKAEKRKLQRELRSALDKTEEL 369
ALE + +R ++A E AEK E D L+ +R+LQ+EL D T +L
Sbjct: 1444 ALE------AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDL 1494
Query: 370 EVSNGHLVKRLEKMKANRSALLSQQ 394
E LV LEK + LL+++
Sbjct: 1495 E-QQRQLVSTLEKKQRKFDQLLAEE 1518
Score = 46.6 bits (109), Expect = 4e-05
Identities = 78/392 (19%), Positives = 152/392 (38%), Gaps = 80/392 (20%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+ S + R+ D L E + + + A AE RE + L + EE+ ++
Sbjct: 1500 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREE 1559
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
E+ +R + A L+S D S+ E++ + E+
Sbjct: 1560 LERQNRALRAELEALLSSKD---------------DVGKSVHELERACRVAEQAANDLRA 1604
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFA- 179
+L++E T +D L LE + + Q+E ++ + A + Q A
Sbjct: 1605 QVTELEDELT-------AAEDAKLRLEVTVQALKTQHE---RDLQGRDEAGEERRRQLAK 1654
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNA-LKSTGDG 238
++++A +R+E ++ + + + GE EEL A + S G G
Sbjct: 1655 QLRDAEVERDEERKQRTLAVAARKKLEGEL-----------------EELKAQMASAGQG 1697
Query: 239 TLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRD 298
+E ++Q++K++ Q++E + +V E T + Q
Sbjct: 1698 ------------KEEAVKQLRKMQAQMKELWR-----------EVEETRTSREEIFSQ-- 1732
Query: 299 ANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRE 358
NR+ SE+ + LE V+RL+ +++ A A++ DE+ E
Sbjct: 1733 -NRE----------SEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1781
Query: 359 LRSALDKTEELEVSNGHLVKRLEKMKANRSAL 390
+ L++ +LE G L + LE+ ++N L
Sbjct: 1782 KAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1813
Score = 42.4 bits (98), Expect = 7e-04
Identities = 96/460 (20%), Positives = 182/460 (39%), Gaps = 95/460 (20%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVE------ERPEKDFTEKGSRNM 68
L E +L A L++ + AR E + R + LE Q +EV+ ER + EK R
Sbjct: 1287 LEAEVSEL-RAELSSLQTARQEGEQ-RRRRLELQLQEVQGRAGDGERARAEAAEKLQR-- 1342
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISID---TEASIREIKDSLAEVEEKYKKAMVSNAQ- 124
+ A L ++ G + S +S + TEA + + ++ L E E + K A+ S +
Sbjct: 1343 ---AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE-ETRAKLALGSRVRA 1398
Query: 125 LDNEKTNFMYQVDTLKDM-------LLELEEQLAESRRQYEEKNKEFE----------RE 167
++ E Q++ L + QL+E RR+ EE+ E RE
Sbjct: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1458
Query: 168 KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKE 227
A + + E + L++ L++ ++ + TL + + +E
Sbjct: 1459 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518
Query: 228 ELNALKSTGDGTLDIRLKKLVDEREC-------LLEQIKKLKGQLEERQKIGKLDN---L 277
+ L++ + R + ERE LE+ ++ + +LE + + + + L
Sbjct: 1519 KAAVLRAVEERE---RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1575
Query: 278 RSEDDVLENGTDMHVMDLQ-RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKS 336
S+DDV G +H ++ R A + +DL+ ++ + E E+TA E +RLE V K+
Sbjct: 1576 SSKDDV---GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1632
Query: 337 AAEN----------------------------------------AEKIE---DELKAEKR 353
E +K+E +ELKA+
Sbjct: 1633 QHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA 1692
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+ A+ + +++ L + +E+ + +R + SQ
Sbjct: 1693 SAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1732
Score = 40.0 bits (92), Expect = 0.004
Identities = 76/380 (20%), Positives = 149/380 (39%), Gaps = 40/380 (10%)
Query: 10 REIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMP 69
RE EAQ+ E+ A+ A + R++ +ELE + E+E+ + ++ R+
Sbjct: 1172 REAQAALAEAQEDLESERVARTKAEKQRRDLG-EELEALRGELEDTLDSTNAQQELRSKR 1230
Query: 70 GLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKD----SLAEVEEKYKKAMVSNAQL 125
L + +T I EA+++E++ +L E+ E+ ++A
Sbjct: 1231 EQEVTEL-------KKTLEEETRIH---EAAVQELRQRHGQALGELAEQLEQARRGKGAW 1280
Query: 126 DNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEAL 185
+ + +V L+ L L+ E ++ + + + + AE E L
Sbjct: 1281 EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKL 1340
Query: 186 KQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNALKSTGDGT---- 239
++ + LE LN + S L++ Q ++ +EE A + G
Sbjct: 1341 QRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAME 1400
Query: 240 -----LDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMD 294
L +L++ RE +++ + QL E ++ E LE G +
Sbjct: 1401 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRR-----RQEEEAGALEAGEEA---- 1451
Query: 295 LQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK 354
+R A R+ L +LA+ + + LE+ RL+ ++ E ++ L+ ++RK
Sbjct: 1452 -RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRK 1510
Query: 355 ----LQRELRSALDKTEELE 370
L E + L EE E
Sbjct: 1511 FDQLLAEEKAAVLRAVEERE 1530
Score = 35.0 bits (79), Expect = 0.12
Identities = 89/408 (21%), Positives = 168/408 (41%), Gaps = 71/408 (17%)
Query: 19 AQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
A + A L + A ARE +EL+ Q ++ E + E G+
Sbjct: 1398 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGA-----------LE 1446
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
G + RR + + A E D L + ++ + +A +D E+ + V T
Sbjct: 1447 AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQEL-DDATMDLEQQRQL--VST 1503
Query: 139 LKDMLLELEEQLAESR----RQYEEKNKEF----EREKHAHSILQFQFAEVKEALKQREE 190
L+ + ++ LAE + R EE+ + ERE A S+ + ++E + REE
Sbjct: 1504 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR----ALEEEQEAREE 1559
Query: 191 MLEKHGIILNSEIATNGETSDTLNNVGYQ--GPTKMTKEELNALKSTGDGTLDIRLKKLV 248
LE+ L +E+ + D + ++ ++ ++ N L++ L+ L
Sbjct: 1560 -LERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT-ELEDELTAAE 1617
Query: 249 DERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANR------- 301
D + L ++ LK Q ER G+ + E+ + + +++RD R
Sbjct: 1618 DAKLRLEVTVQALKTQ-HERDLQGRDE--AGEERRRQLAKQLRDAEVERDEERKQRTLAV 1674
Query: 302 --------QISDLKFKLAKSEQ-------EITALEQNVIRL-----ESQVSRYKSAAEN- 340
++ +LK ++A + Q ++ ++ + L E++ SR + ++N
Sbjct: 1675 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1734
Query: 341 -AEKIEDELKAEKRKLQREL-------RSALDKTEEL--EVSNGHLVK 378
+EK L+AE +LQ EL R A +E+ EV+NG+L K
Sbjct: 1735 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSK 1782
Score = 33.9 bits (76), Expect = 0.26
Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Query: 270 KIGKLDNLRSEDDVLENGTD--MHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRL 327
K+ L + +D+VL+ V +LQ+ + R++ +L+ ++A+ LE+ RL
Sbjct: 898 KVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEERARL 950
Query: 328 ESQVSRYKSAAENAEKIEDELKAEKRKLQ---RELRSALDKTEE----LEVSNGHLVKRL 380
Q+ AE+ L A K++L+ EL + + + EE ++ L + +
Sbjct: 951 AEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHI 1010
Query: 381 EKMKANRSA 389
++++A+ A
Sbjct: 1011 QELEAHLEA 1019
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 63.9 bits (154), Expect = 2e-10
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 42/351 (11%)
Query: 41 RMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGT--SSRRGSGDTSISIDTE 98
+MK L R + EE +G R + A L T S + D ++ + E
Sbjct: 884 KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943
Query: 99 ASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYE 158
+D+LA+ EE+ + S QL+ + +++ + E+ LA RR+ E
Sbjct: 944 ------QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEE----EVNADLAARRRKLE 993
Query: 159 EKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGY 218
++ E +++ + + + K+A + + + L + L+ +A + L
Sbjct: 994 DECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQ 1053
Query: 219 Q--GPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDN 276
Q G + ++ ++AL +RL++ V++ EC LEQ KKL+ E ++ + D
Sbjct: 1054 QALGDLQAEEDRVSALTKA-----KLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDL 1108
Query: 277 LRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITAL-----EQNVIRLESQV 331
+++ V DA + L+ KL K + E++ L ++ ++ + Q
Sbjct: 1109 KLTQESVA-------------DAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQ- 1154
Query: 332 SRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEK 382
+ K AE++E+EL+AE+ R + + ELE L +RLE+
Sbjct: 1155 KKIKELQARAEELEEELEAERAARARVEKQRAEAARELE----ELSERLEE 1201
Score = 56.2 bits (134), Expect = 5e-08
Identities = 101/482 (20%), Positives = 180/482 (37%), Gaps = 100/482 (20%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMK-----ELERQQKEVE-- 53
+T AA + L+ E + L EA A +AE + LE+Q +++E
Sbjct: 1027 LTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECS 1086
Query: 54 ---ERPEKDFTEKGSRNMPGLSAATLASLGGTS--------------------SRRGSGD 90
E+ + TE+ R + G T S+ + S R +
Sbjct: 1087 LEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDE 1146
Query: 91 TSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLEL---- 146
+ + I+E++ E+EE+ + + A+++ ++ +++ L + L E
Sbjct: 1147 QLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGAS 1206
Query: 147 ----------EEQLAESRRQYEEKNKEFE------REKHAHSILQFQFAEVKEALKQREE 190
E +L RR+ EE E R K A + E ++L++ +
Sbjct: 1207 AGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAA--ELGEQVDSLQRVRQ 1264
Query: 191 MLEKHGIILNSEIATNGETSDTLNNV------------GYQGPTKMTKEELN---ALKST 235
LEK L E+ +TL K+ EEL A ST
Sbjct: 1265 KLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADAST 1324
Query: 236 GDGTLDI---RLKKLVDERECLLEQ-----------IKKLKGQLEERQKIGK-----LDN 276
G L L +L++E+ECL+ Q +++L+ QLEE K +
Sbjct: 1325 QRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQA 1384
Query: 277 LRSEDDVL------ENGTDMHVMDLQRDANRQISDLKFK-----LAKSEQEITALEQNVI 325
LR + D+L E + L AN +++ + K + ++E+ A ++ +
Sbjct: 1385 LRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLAL 1444
Query: 326 RL---ESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEK 382
RL E V + + EK + L+ E + EL A L+ HL + LE+
Sbjct: 1445 RLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEE 1504
Query: 383 MK 384
+
Sbjct: 1505 RR 1506
Score = 52.8 bits (125), Expect = 5e-07
Identities = 62/295 (21%), Positives = 119/295 (40%), Gaps = 61/295 (20%)
Query: 99 ASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQ---LAESRR 155
A +R ++ +LA E K ++ ++ + EK + Q+ +D L + EE+ L +S+
Sbjct: 903 AELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKV 962
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNN 215
Q E K KE + E L+ EE+ N+++A
Sbjct: 963 QLEGKVKE-----------------LSERLEDEEEV--------NADLAAR--------- 988
Query: 216 VGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLD 275
+ ++E LK D L + L K E++ ++K L ++ + +
Sbjct: 989 ------RRKLEDECTELKKDIDD-LKLTLAKAEKEKQATENKVKNLTEEMAALDE--SVA 1039
Query: 276 NLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYK 335
L E L+ + DLQ + +R ++AL + +RLE QV +
Sbjct: 1040 RLTKEKKALQEAHQQALGDLQAEEDR---------------VSALTKAKLRLEQQVEDLE 1084
Query: 336 SAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSAL 390
+ E +K+ + + KRKL+ +L+ + + L ++L+K + S L
Sbjct: 1085 CSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Score = 50.8 bits (120), Expect = 2e-06
Identities = 86/431 (19%), Positives = 175/431 (40%), Gaps = 67/431 (15%)
Query: 19 AQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
AQ L E R + ++A++ + R ++ ++ E + LS A A
Sbjct: 1358 AQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKAN-AE 1416
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
+ S+ + + + E + +++ L E EE + A + L EK Q ++
Sbjct: 1417 VAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSL--EKAKLRLQTES 1474
Query: 139 LKDMLLELEEQ-----------------LAESRRQYEEKNKEFE--------------RE 167
+D+ LELE L E RRQ EE +E E R
Sbjct: 1475 -EDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRL 1533
Query: 168 KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKE 227
+H H + E E LK+ + L++ L +++ +G++ L + + K
Sbjct: 1534 RHGHE----EALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKT--KKALEGEKS 1587
Query: 228 ELNALKSTGDGTLDIRLKKLVDERECLLEQIK-----KLKGQLEERQKIGK-----LDNL 277
E+ A +G L++ K + + L Q+K KL + EE + + +++L
Sbjct: 1588 EIQAALEEAEGALELEETKTL-RIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESL 1646
Query: 278 RSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSA 337
++ D E + L++ ++DL+ +L + ++ T + +++Q+ ++
Sbjct: 1647 QASLDA-ETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAG 1705
Query: 338 AENAEKIEDELKAEKRKLQR----------ELRSALDKTEE----LEVSNGHLVKRLEKM 383
+ +++ EL + + L+R ELR+AL++ E E +RL +
Sbjct: 1706 RDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLL 1765
Query: 384 KANRSALLSQQ 394
+ + LL+Q+
Sbjct: 1766 HSQNTGLLNQK 1776
Score = 37.0 bits (84), Expect = 0.031
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRM--KELERQQKEVE--ERPEKDFTEKGSRNMPG 70
LS E ++ A+ R A+ A+ + M +EL+++Q ER +K +
Sbjct: 1786 LSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQAR 1845
Query: 71 LSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKT 130
L A A+L G G + EA +RE++ L ++K+ +A+ + +
Sbjct: 1846 LEEAEQAALRG-------GKKQVQ-KLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 1897
Query: 131 NFMYQVD-------TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKE 183
YQ + ++D++ +L+ ++ +RQ+EE ++ + Q + + +E
Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957
Query: 184 ALKQREEMLEK 194
E K
Sbjct: 1958 RADMAETQANK 1968
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 63.5 bits (153), Expect = 3e-10
Identities = 80/377 (21%), Positives = 165/377 (43%), Gaps = 48/377 (12%)
Query: 20 QKLAEARLAAKRAARAEAREIRMK--ELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
+ LAE +R R+ R K E++ +K++++ EK +G + S L
Sbjct: 620 EALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLK 679
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQ------------- 124
+ + G S E ++ + K+ ++E + KKA + +
Sbjct: 680 EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQH 739
Query: 125 LDNEKTNF-------MYQVDTLKDMLLELEEQ-------LAESRRQYEEKNKEFEREKHA 170
L+ E T + +VD L ++L E+E + +AE RQ +++NK+ KH
Sbjct: 740 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHK 799
Query: 171 HSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQG-PTKMTKEEL 229
+ + + A++ E ++RE+ L L + + + L + +E +
Sbjct: 800 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 859
Query: 230 NALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQ-----KIGKLDNLRSE---- 280
A + + + ++++L+ E + ++++ +K +L Q K L NLR+E
Sbjct: 860 LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH 919
Query: 281 -DDVLENGTDMHVMDL-QRDANRQISDLKFKLAKSEQEITALEQNVIRLESQV-----SR 333
++VLE + + + ++DAN + +L K+++E+ AL++ RL Q+ +R
Sbjct: 920 LEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNR 979
Query: 334 YKSAAENAEKIEDELKA 350
K A+N E +D K+
Sbjct: 980 MKLMADNYE--DDHFKS 994
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/326 (22%), Positives = 150/326 (46%), Gaps = 41/326 (12%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
+T+ ++ ++++LAE E ++ Q D ++ ++D K L +L+E+++ +
Sbjct: 610 NTDTALTTLEEALAEKERTIERL---KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG 666
Query: 156 QYEEKNKEF-EREKHAHSI-------------LQFQFAEVKEALKQREEMLEK-HGIILN 200
EK + ++HA S+ L+ + KE + E L+K H L
Sbjct: 667 DLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAAL- 725
Query: 201 SEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKK 260
E + E SD + ++ + K+E + ++ D L+I LK++ +E+ ++I +
Sbjct: 726 -EARASPEMSDRIQHL--EREITRYKDESSKAQAEVDRLLEI-LKEVENEKNDKDKKIAE 781
Query: 261 LKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQR------DANRQISDLKFKLAKSE 314
L+ Q++++ K K+ NL+ ++ V + + + + +R D+++Q+ D L K +
Sbjct: 782 LERQVKDQNK--KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKKD 836
Query: 315 QEITALE-------QNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTE 367
I LE Q E +++ +SA NAEK +EL K+++EL S K
Sbjct: 837 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 896
Query: 368 ELEVSNGHLVKRLEKMKANRSALLSQ 393
+ S L ++A R L +
Sbjct: 897 STQQSLAEKETHLTNLRAERRKHLEE 922
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/397 (21%), Positives = 166/397 (41%), Gaps = 70/397 (17%)
Query: 23 AEARLAAKRAARAEAREIRMKE----LERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
A+ + AA +A +R++E L ++ K++++ E+ T+ G + L
Sbjct: 512 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH-------DLKD 564
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
+ R+ + + + +R+ + ++ ++E+ K D T
Sbjct: 565 MLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT------- 617
Query: 139 LKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML-----E 193
LEE LAE R E ++ +R++ + + + LK++ +L E
Sbjct: 618 -------LEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 670
Query: 194 KHGIILN-----SEIATNGETSD----TLNNVGYQGPTKMTKEELNALKSTGDGTLDIRL 244
K +L+ S +A++G D TL Q + K E + LK + L+ R
Sbjct: 671 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME-SQLKKAHEAALEARA 729
Query: 245 K-KLVDERECLLEQIKKLKGQLEERQ-KIGKLDNLRSEDDVLENGTDMHVMDLQR---DA 299
++ D + L +I + K + + Q ++ +L + E + +N D + +L+R D
Sbjct: 730 SPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQ 789
Query: 300 NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSA--AENAEKIEDELKAEKRKLQR 357
N+++++LK K QV + KSA E A + ED L ++LQ
Sbjct: 790 NKKVANLKHK-------------------EQVEKKKSAQMLEEARRREDNLNDSSQQLQD 830
Query: 358 ELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
LR D+ EELE ++ ++ A R +L+Q+
Sbjct: 831 SLRKKDDRIEELE----EALRESVQITAEREMVLAQE 863
Score = 54.3 bits (129), Expect = 2e-07
Identities = 101/437 (23%), Positives = 182/437 (41%), Gaps = 78/437 (17%)
Query: 25 ARLAAKRAARAEAREIRM-KELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASL---G 80
A L + R A R KEL +K +EE + T+K + N S L +
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK 319
Query: 81 GTSSRRGSGD---TSISIDTEASIREIKDSLAEVEEKYKKAM-------VSNAQLDNEKT 130
G S++ D T + E + + +SL E +EK + NA D+ KT
Sbjct: 320 GLSAKATEEDHERTRRLAEAEMHVHHL-ESLLEQKEKENSMLREEMHRRFENAP-DSAKT 377
Query: 131 NFMYQVDTLKDM--------LLELEEQL-------AESRRQYEEKNKEFEREKHAHSILQ 175
+ V +KD L +LEE++ A S + EE+ K+ E + ++
Sbjct: 378 KALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK 437
Query: 176 FQFAEVKEALKQRE---EMLEKHGIILNSEIA-----------------TNGET-----S 210
+ ++KE L +E E L+K L +EI T ET S
Sbjct: 438 NKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLL-EQIKKLKGQLEER- 268
D+ ++ + KE+ A+ T L +RL +E+E +L ++ K+++ EE+
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRL----EEKETMLNKKTKQIQDMAEEKG 553
Query: 269 QKIGKLDNLRSEDDVLENGTDM------HVMDLQRDANRQISDLKFKL-------AKSEQ 315
+ G++ +L+ DV E ++ ++ + RD +Q+S LK ++ ++
Sbjct: 554 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDT 613
Query: 316 EITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGH 375
+T LE+ + E + R K E ++ E E + E +++L+ +K L+
Sbjct: 614 ALTTLEEALAEKERTIERLK---EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 670
Query: 376 LVKRLEKMKANRSALLS 392
L +K + S+L S
Sbjct: 671 KEASLLDLKEHASSLAS 687
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 63.5 bits (153), Expect = 3e-10
Identities = 80/377 (21%), Positives = 165/377 (43%), Gaps = 48/377 (12%)
Query: 20 QKLAEARLAAKRAARAEAREIRMK--ELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
+ LAE +R R+ R K E++ +K++++ EK +G + S L
Sbjct: 592 EALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLK 651
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQ------------- 124
+ + G S E ++ + K+ ++E + KKA + +
Sbjct: 652 EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQH 711
Query: 125 LDNEKTNF-------MYQVDTLKDMLLELEEQ-------LAESRRQYEEKNKEFEREKHA 170
L+ E T + +VD L ++L E+E + +AE RQ +++NK+ KH
Sbjct: 712 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHK 771
Query: 171 HSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQG-PTKMTKEEL 229
+ + + A++ E ++RE+ L L + + + L + +E +
Sbjct: 772 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 831
Query: 230 NALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQ-----KIGKLDNLRSE---- 280
A + + + ++++L+ E + ++++ +K +L Q K L NLR+E
Sbjct: 832 LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH 891
Query: 281 -DDVLENGTDMHVMDL-QRDANRQISDLKFKLAKSEQEITALEQNVIRLESQV-----SR 333
++VLE + + + ++DAN + +L K+++E+ AL++ RL Q+ +R
Sbjct: 892 LEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNR 951
Query: 334 YKSAAENAEKIEDELKA 350
K A+N E +D K+
Sbjct: 952 MKLMADNYE--DDHFKS 966
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/326 (22%), Positives = 150/326 (46%), Gaps = 41/326 (12%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
+T+ ++ ++++LAE E ++ Q D ++ ++D K L +L+E+++ +
Sbjct: 582 NTDTALTTLEEALAEKERTIERL---KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG 638
Query: 156 QYEEKNKEF-EREKHAHSI-------------LQFQFAEVKEALKQREEMLEK-HGIILN 200
EK + ++HA S+ L+ + KE + E L+K H L
Sbjct: 639 DLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAAL- 697
Query: 201 SEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKK 260
E + E SD + ++ + K+E + ++ D L+I LK++ +E+ ++I +
Sbjct: 698 -EARASPEMSDRIQHL--EREITRYKDESSKAQAEVDRLLEI-LKEVENEKNDKDKKIAE 753
Query: 261 LKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQR------DANRQISDLKFKLAKSE 314
L+ Q++++ K K+ NL+ ++ V + + + + +R D+++Q+ D L K +
Sbjct: 754 LERQVKDQNK--KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKKD 808
Query: 315 QEITALE-------QNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTE 367
I LE Q E +++ +SA NAEK +EL K+++EL S K
Sbjct: 809 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 868
Query: 368 ELEVSNGHLVKRLEKMKANRSALLSQ 393
+ S L ++A R L +
Sbjct: 869 STQQSLAEKETHLTNLRAERRKHLEE 894
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/397 (21%), Positives = 166/397 (41%), Gaps = 70/397 (17%)
Query: 23 AEARLAAKRAARAEAREIRMKE----LERQQKEVEERPEKDFTEKGSRNMPGLSAATLAS 78
A+ + AA +A +R++E L ++ K++++ E+ T+ G + L
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH-------DLKD 536
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDT 138
+ R+ + + + +R+ + ++ ++E+ K D T
Sbjct: 537 MLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT------- 589
Query: 139 LKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML-----E 193
LEE LAE R E ++ +R++ + + + LK++ +L E
Sbjct: 590 -------LEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 642
Query: 194 KHGIILN-----SEIATNGETSD----TLNNVGYQGPTKMTKEELNALKSTGDGTLDIRL 244
K +L+ S +A++G D TL Q + K E + LK + L+ R
Sbjct: 643 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME-SQLKKAHEAALEARA 701
Query: 245 K-KLVDERECLLEQIKKLKGQLEERQ-KIGKLDNLRSEDDVLENGTDMHVMDLQR---DA 299
++ D + L +I + K + + Q ++ +L + E + +N D + +L+R D
Sbjct: 702 SPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQ 761
Query: 300 NRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSA--AENAEKIEDELKAEKRKLQR 357
N+++++LK K QV + KSA E A + ED L ++LQ
Sbjct: 762 NKKVANLKHK-------------------EQVEKKKSAQMLEEARRREDNLNDSSQQLQD 802
Query: 358 ELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQQ 394
LR D+ EELE ++ ++ A R +L+Q+
Sbjct: 803 SLRKKDDRIEELE----EALRESVQITAEREMVLAQE 835
Score = 36.6 bits (83), Expect = 0.040
Identities = 71/371 (19%), Positives = 143/371 (38%), Gaps = 32/371 (8%)
Query: 36 EAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI 95
+AR+ + +L+ Q KEV E D K ++++ S+ S + ++
Sbjct: 145 QARDNTIMDLQTQLKEVLR--ENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRK 202
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNE-----KTNFMYQVD----TLKDMLLEL 146
D + I K+ V+E+ + ++ L +E N ++Q D T + + EL
Sbjct: 203 DEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAEL 262
Query: 147 -EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIAT 205
EE ++E + KE + ++ + K+ L R+E ++K +L S+ +
Sbjct: 263 TEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLS 322
Query: 206 NGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL 265
T + +M L +L L++ E L E++ +
Sbjct: 323 AKATEEDHERTRRLAEAEMHVHHLESL-----------LEQKEKENSMLREEMHRRFENA 371
Query: 266 EERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVI 325
+ K L + D + + + DL+ + S+ + E+E+ +E V
Sbjct: 372 PDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQME--VY 429
Query: 326 RLESQVSRYK--SAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKM 383
R S+ + K + + + EL A + KL+ D + +EV +K
Sbjct: 430 RSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEV-----LKESLTA 484
Query: 384 KANRSALLSQQ 394
K R+A+L +
Sbjct: 485 KEQRAAILQTE 495
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 63.5 bits (153), Expect = 3e-10
Identities = 71/318 (22%), Positives = 142/318 (44%), Gaps = 32/318 (10%)
Query: 108 LAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE-- 165
++++EE+ KK + +L+ K + L+D + EL+ Q+ E + Q +K +E +
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1095
Query: 166 ---------REKHAHSI---LQFQFAEVK---EALKQREEMLEKHGIILNSEI-ATNGET 209
+ +A + LQ Q AE++ E+ K EK L+ E+ A E
Sbjct: 1096 LARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Query: 210 SDTLNNVGYQGP--TKMTKEELNALKSTGDGT-------LDIRLK--KLVDERECLLEQI 258
DTL+ Q TK +E K+ + T D+R + ++E LEQ
Sbjct: 1156 EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA 1215
Query: 259 KKLKGQLEERQKIGKLDN--LRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQE 316
K+ K LE+ ++ + DN L E VL+ ++ + Q+ +L K+++ ++
Sbjct: 1216 KRFKANLEKNKQGLETDNKELACEVKVLQQ-VKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
Query: 317 ITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHL 376
L + +L++++ + E AEK + + L+ +L+ + +E +L
Sbjct: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
Query: 377 VKRLEKMKANRSALLSQQ 394
R+ +++ +++L QQ
Sbjct: 1335 SSRIRQLEEEKNSLQEQQ 1352
Score = 62.8 bits (151), Expect = 5e-10
Identities = 82/424 (19%), Positives = 178/424 (41%), Gaps = 55/424 (12%)
Query: 13 DCLSPEAQKLAEARLAAKRAARAEAR-EIRMKELERQQKEVEERPEKDFTEKGSRNMPGL 71
D ++ + +LAE AK A+ + E+ + +LE + K+ E+ ++ EK R + G
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQE--LEKAKRKLDGE 1063
Query: 72 SAATLASLGGTSSR--------------------RGSGDTSISIDTEASIREIKDSLAEV 111
+ + ++ RG +T + +RE++ +AE+
Sbjct: 1064 TTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAEL 1123
Query: 112 EEKYKKAMVSNAQLDNEKTNFMYQVDTLK--------------DMLLELEEQLAESRRQY 157
+E ++ S + + +K + +++ LK ++ + E+++AE ++
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 158 EEKNKEFERE----KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTL 213
EE+ K E + + H+ + +E E K+ + LEK+ L ++ L
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 214 NNVGYQGPTKMTK-----EELNALKSTGD------GTLDIRLKKLVDERECLLEQIKKLK 262
V + K K +EL+A S GD +L+ +D LLE+ +K K
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK-K 1302
Query: 263 GQLEERQKIGKLDNLRSEDDVLENGT--DMHVMDLQRDANRQISDLKFKLAKSEQEITAL 320
G + L+ ++L+ T +++ R + + L+ + + E+ L
Sbjct: 1303 GIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNL 1362
Query: 321 EQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRL 380
E+ V+ L+SQ++ K ++ + L+ K+KL ++ + + EE ++ L K
Sbjct: 1363 EKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTK 1422
Query: 381 EKMK 384
+++
Sbjct: 1423 NRLQ 1426
Score = 60.1 bits (144), Expect = 3e-09
Identities = 87/449 (19%), Positives = 181/449 (40%), Gaps = 73/449 (16%)
Query: 13 DCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLS 72
D S E+Q L + + R+++LE ++ ++E+ E++ E+ +N+
Sbjct: 1309 DAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE--EEARKNLEKQV 1366
Query: 73 AATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLA---EVEEK---YKKAMVSNAQLD 126
A + L T + +I EA + +KD+ A +EEK Y K + +L
Sbjct: 1367 LALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ 1426
Query: 127 NEKTNFMYQVDTLKDMLLELEEQ-------LAESRR---QYEEKNKEFEREKHAHSILQF 176
E + +D + + LE++ LAE + +Y E+ E E
Sbjct: 1427 QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKAL 1486
Query: 177 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLN-NVGYQGPTKMTKEE------- 228
A E + +E E+ L +++ + D + NV +K E+
Sbjct: 1487 SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546
Query: 229 ----------------------LNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE 266
+ A+K+ + L R ++ +++ L++Q+++L+ +LE
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELE 1606
Query: 267 ERQKIGKL------------DNLRSEDDVLENGTDMHVMDLQR------DANRQISDLK- 307
+ +K L +L ++ + D + L++ D R++ + +
Sbjct: 1607 DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARA 1666
Query: 308 -----FKLAK-SEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRS 361
F +K SE+++ +LE +++L+ +++ + A +AE+ DEL E +
Sbjct: 1667 SRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSA 1726
Query: 362 ALDKTEELEVSNGHLVKRLEKMKANRSAL 390
LD+ LE L + LE+ ++N L
Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELL 1755
Score = 57.4 bits (137), Expect = 2e-08
Identities = 65/298 (21%), Positives = 129/298 (43%), Gaps = 30/298 (10%)
Query: 101 IREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEK 160
+R+++ + + + + ++A S ++ + ++ +L+ +L+L+E+LA S R +
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERA--RR 1704
Query: 161 NKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQG 220
+ E ER++ A I A K AL + LE L E+ + LN+ +
Sbjct: 1705 HAEQERDELADEITNS--ASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK- 1761
Query: 221 PTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQ----------- 269
T + + LNA + +K + R+ L Q K+LK +L+E +
Sbjct: 1762 -TTLQVDTLNAELAAERSAA----QKSDNARQQLERQNKELKAKLQELEGAVKSKFKATI 1816
Query: 270 -----KIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNV 324
KIG+L+ + E + E L R +++ ++ ++ + ++ +
Sbjct: 1817 SALEAKIGQLEE-QLEQEAKERAA---ANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872
Query: 325 IRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEK 382
+ +++ + K E AE+ A +RKLQREL A + E L L RL +
Sbjct: 1873 EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Score = 52.0 bits (123), Expect = 9e-07
Identities = 79/339 (23%), Positives = 131/339 (38%), Gaps = 69/339 (20%)
Query: 105 KDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEF 164
++ L +E+ K +++ E + +++ LLE + LAE + E E
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGE----LEEMERKHQQLLEEKNILAEQLQAETELFAEA 906
Query: 165 EREKHAHSILQFQFAEVKEALKQR-EEMLEKHGIILNSEIATNGETSD------------ 211
E + + + + E+ L+ R EE E++ I+ N + D
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 212 ---TLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDER--EC---LLEQIKKLK- 262
L V + K +EE+ L+ + I+ KKL+++R EC L E+ +K K
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLED--QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKN 1024
Query: 263 ------------GQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQ---RDANRQISDLK 307
LEER K K + R E + + D DLQ + QI +LK
Sbjct: 1025 LAKIRNKQEVMISDLEERLK--KEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 308 FKLAKSEQE---------------------ITALEQNVIRLESQVSRYKSAAENAEKIED 346
+LAK E+E + L+ + L+ K++ AEK +
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142
Query: 347 ELKAEKRKLQRELRSALDKT---EELEVSNGHLVKRLEK 382
+L E L+ EL LD T +EL V L+K
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKK 1181
Score = 45.8 bits (107), Expect = 7e-05
Identities = 62/304 (20%), Positives = 115/304 (37%), Gaps = 71/304 (23%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE---QLAESR 154
+ + ++K+ +VE + ++ + QL EK Q+ ++ E EE +LA +
Sbjct: 858 DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
Query: 155 RQYEE----KNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 210
++ EE E E+ + ILQ + +++ ++ EE L++
Sbjct: 918 QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE---------EGARQK 968
Query: 211 DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL-EERQ 269
L V + K +EE+ L+ K + E++ + ++I + QL EE +
Sbjct: 969 LQLEKVTAEAKIKKMEEEILLLEDQNS--------KFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 270 KIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLES 329
K L +R++ +V+ ISDL+ +L K E
Sbjct: 1021 KAKNLAKIRNKQEVM------------------ISDLEERLKKEE--------------- 1047
Query: 330 QVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
K EL+ KRKL E D+ EL+ L +L K +
Sbjct: 1048 -------------KTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
Query: 390 LLSQ 393
L++
Sbjct: 1095 ALAR 1098
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 62.8 bits (151), Expect = 5e-10
Identities = 92/424 (21%), Positives = 198/424 (46%), Gaps = 56/424 (13%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKE-----VEERPEKDFTEKGSRNMPGLS 72
E ++L+ +L K A+ ++++ LE Q KE E + + D T++ + L
Sbjct: 439 EQRQLSSEKLMDKEQQVADL-QLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ 497
Query: 73 AATLASLGGTSSR-----RGSGDTSISIDT-EASIREIKDSLAEVEEKYKKAMVSNAQLD 126
+T A L + R GD I EA +++ K++++ +E K ++ + + Q
Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLE-KEREDLYAKIQAG 556
Query: 127 NEKTNFMYQVD----TLKDMLLELEEQL---AESRRQYEEKNKEFEREKHAH-------- 171
+T + Q+ TL++ + +L E+L +ES +Q +E + +E+ AH
Sbjct: 557 EGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 172 -------SILQFQFAEVKEALKQREEMLE-KHGIILNSEIATNGETSDTLNNVGY-QGPT 222
+ L Q E KE + Q + ++ K ++L++E A + +D N++ Q
Sbjct: 617 LSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNAL 676
Query: 223 KMTKEELNALKSTGDGTLDIRLKKLVDERECL------LEQIKKLKGQLEERQKI--GKL 274
+ ++ELN + + LD KL D++E L++ K+ LE++ + G++
Sbjct: 677 QDKQQELNKITTQ----LDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 275 DNLRSEDDVLENGTDMHVMDLQRDANRQIS-DLKFKLAKSEQEITALEQNVIRLESQVSR 333
L ++ ++ + + DLQ+ RQ++ DL+ + + +++ ++ V + +
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQ--RQLNTDLELRATELSKQLEMEKEIVSSTRLDLQK 790
Query: 334 YKSAAENAEKIEDELKAEKRKLQRELRSALDKT----EELEVSNGHLVKRLEKMKANRSA 389
A E+ ++ + + EK+ L+++ + +T EEL V L+K+K + A
Sbjct: 791 KSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEA 850
Query: 390 LLSQ 393
L+++
Sbjct: 851 LMTE 854
Score = 57.0 bits (136), Expect = 3e-08
Identities = 95/441 (21%), Positives = 194/441 (43%), Gaps = 88/441 (19%)
Query: 1 MTSPAAAQSREIDCLSPEAQKL------AEARLAAKRAARAEARE---IRMKELERQQKE 51
M + + RE + L E +KL +EA ++ R+ A+ + + ++EL++ +
Sbjct: 237 MDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSS 296
Query: 52 VEE-------------RPEKDFTE-KGSRNMPGLSAATLASL--------GGTSSRRGSG 89
V E + E+D+T+ + N +S + + SR +
Sbjct: 297 VNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS 356
Query: 90 DTSIS-IDTEAS-----IREIKDSLAEVEEKYKKAMVSNAQLDNEK-------TNFMYQV 136
+TS+ I E S +++K+ L+EVE KY+ QL ++ ++
Sbjct: 357 ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI 416
Query: 137 DTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHG 196
+ L LLE E QL E+ + +E+ ++ EK + Q A+++ L + EE L++
Sbjct: 417 NQLHSKLLETERQLGEAHGRLKEQ-RQLSSEKLMDK--EQQVADLQLKLSRLEEQLKE-- 471
Query: 197 IILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLE 256
++ + E L+ TK +E AL+ + +L++ ++ E +L
Sbjct: 472 -----KVTNSTELQHQLDK------TKQQHQEQQALQQ----STTAKLREAQNDLEQVLR 516
Query: 257 QIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQE 316
QI ++ QKI L+ L + ++ ++ +++ +R+ DL K+ E E
Sbjct: 517 QIG------DKDQKIQNLEAL-----LQKSKENISLLEKERE------DLYAKIQAGEGE 559
Query: 317 ---ITALEQNVIRLESQVS----RYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEEL 369
+ L++ L+ QV+ + K+ +E+ ++ ++ L + ++ + LR+A D+ L
Sbjct: 560 TAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSL 619
Query: 370 EVSNGHLVKRLEKMKANRSAL 390
E S L +L + K S L
Sbjct: 620 ETSVNELNSQLNESKEKVSQL 640
Score = 48.5 bits (114), Expect = 1e-05
Identities = 69/295 (23%), Positives = 118/295 (40%), Gaps = 15/295 (5%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQY 157
E+ + + L VEEK A N+ N + LK LE+ A+ +Q
Sbjct: 1039 ESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQL 1098
Query: 158 EEKNKEFEREKHAHSILQFQFAEVKEALKQREEM---LEKHGIILNSEIATNGETSDTLN 214
+E+ K + + S+ + + K L + EE+ EK LN E+ S L
Sbjct: 1099 QERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL-----KSHKLE 1153
Query: 215 NVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDE----RECLLEQIKKLKGQLEERQK 270
++ K K+ L K G D LK V++ ++ L +Q+KK + +L +++
Sbjct: 1154 SIKEITNLKDAKQLLIQQKLELQGKAD-SLKAAVEQEKRNQQILKDQVKKEEEEL-KKEF 1211
Query: 271 IGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQ 330
I K L SE E G H + + QI+ L L ++E + ++ V LE Q
Sbjct: 1212 IEKEAKLHSEIKEKEVGMKKH-EENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQ 1270
Query: 331 VSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKA 385
+ E + E+R L + E+L+ L ++L+ A
Sbjct: 1271 TDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTA 1325
Score = 47.0 bits (110), Expect = 3e-05
Identities = 74/349 (21%), Positives = 146/349 (41%), Gaps = 60/349 (17%)
Query: 95 IDTEASIREIKDSLAEVEEKYKKA---MVSNAQLDNEKT-NFMYQVDTLKDMLLELEEQL 150
+ ++ I ++ L E E + +A + QL +EK + QV L+ L LEEQL
Sbjct: 410 LQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQL 469
Query: 151 AESRRQYEEKNKEFEREKHAH----SILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 206
E E + ++ K H ++ Q A+++EA E++L + G
Sbjct: 470 KEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLE 529
Query: 207 GETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLE 266
+ N+ + +E+L A G+G + L +L ++ L EQ+ +L +L+
Sbjct: 530 ALLQKSKENISL---LEKEREDLYAKIQAGEGETAV-LNQLQEKNHTLQEQVTQLTEKLK 585
Query: 267 ERQKIGKLDNLRSEDDVLENGTDMH-----VMDLQ---RDANRQISDLKFKLAKSEQEIT 318
+ + K D V E + V+ L+ + N Q+++ K K+++ + +I
Sbjct: 586 NQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIK 645
Query: 319 ALEQNVIRLES-------QVSRYKSAAENA-------------------EKIED------ 346
A + ++ E+ + + A+NA K++D
Sbjct: 646 AKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCS 705
Query: 347 ELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLE----KMKANRSALL 391
+L++ ++ + + S KTEELE +K+LE ++KA++ L
Sbjct: 706 QLESHLKEYKEKYLSLEQKTEELEGQ----IKKLEADSLEVKASKEQAL 750
Score = 45.4 bits (106), Expect = 9e-05
Identities = 55/293 (18%), Positives = 129/293 (44%), Gaps = 36/293 (12%)
Query: 105 KDSLAEVEEKYKKAMVSNAQL-------DNEKTNFMYQVDTLKDMLLELEEQLAESRRQY 157
K+ ++ ++ Y+K+ + QL ++E + ++++ L +E L +R Q
Sbjct: 1011 KEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQI 1070
Query: 158 EEKNKEFEREKHAHSILQFQFAEVKEALKQREEML---EKHGIILNSEIATNGETSDTLN 214
+NK + K A + L+ A+ ++ L++R + L +K + E+ +
Sbjct: 1071 GNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE 1130
Query: 215 NVGYQGPTKMTK--EELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKG--------- 263
+ + ++TK EEL + K + L D ++ L++Q +L+G
Sbjct: 1131 EIKCRQEKEITKLNEELKSHKLESIK----EITNLKDAKQLLIQQKLELQGKADSLKAAV 1186
Query: 264 QLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQ-------E 316
+ E+R + D ++ E++ L+ ++ + + +I + + + K E+ +
Sbjct: 1187 EQEKRNQQILKDQVKKEEEELKK----EFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQ 1242
Query: 317 ITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEEL 369
ITAL +N+ ++ + + EK D+L+ E L+ +++ D+ L
Sbjct: 1243 ITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRAL 1295
Score = 45.1 bits (105), Expect = 1e-04
Identities = 75/384 (19%), Positives = 162/384 (42%), Gaps = 52/384 (13%)
Query: 34 RAEAREIRMKELERQQKEVEERPEK-DFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 92
R + E + EL Q E +E+ + D K + L +A A + + DT+
Sbjct: 615 RVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTEL--LLSAEAAKTAQRADLQNHLDTA 672
Query: 93 ISI--DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQL 150
+ D + + +I L +V K + +QL++ + + +L+ ELE Q+
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 151 A-------ESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEM-------LEKHG 196
E + E+ ++ ++++ ++ L+ + E+ + L+ +E+ L+K
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 197 IILNS--EIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECL 254
L S + T E + ++ ++ TK + L + T+ L+K+ E+E L
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVT-ELQKVKMEKEAL 851
Query: 255 LEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN-------------- 300
+ ++ +K +L + L N +SE + ++DL++
Sbjct: 852 MTELSTVKDKLSKVSD--SLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTL 909
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA---------- 350
++ +LK L K ++ L+ + ++ Q+ + ++ + EK E +L+
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSE 969
Query: 351 EKRK----LQRELRSALDKTEELE 370
+K+K LQ EL+ A+ + ELE
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELE 993
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 62.4 bits (150), Expect = 7e-10
Identities = 89/421 (21%), Positives = 170/421 (40%), Gaps = 69/421 (16%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTS 83
E L A+R ARA+ ++R +L R+ +E+ ER E E G +
Sbjct: 1121 EEELEAERTARAKVEKLR-SDLSRELEEISERLE----EAGGATSVQIEMNKKREAEFQK 1175
Query: 84 SRRGSGDTSISIDTEASIREIK--DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD---- 137
RR + ++ + A+ K DS+AE+ E+ +L+ EK+ F ++D
Sbjct: 1176 MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTS 1235
Query: 138 ----------TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQ 187
L+ + LE+Q E R + EE + + LQ + E+ L++
Sbjct: 1236 NMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE 1295
Query: 188 REEMLEK--HGII--------LNSEIATNGETSDTLNNV-------------GYQGPTKM 224
+E ++ + G + L ++ G+ + L + Y+ T+
Sbjct: 1296 KEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEA 1355
Query: 225 TKEELNALKSTGDGTLDIRLK---KLVDERECLLEQIKKLKGQLEERQKI-----GKLDN 276
E L R K + E L E KKL +L++ ++ K +
Sbjct: 1356 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS 1415
Query: 277 LRSEDDVLENGTDMHVMDL-------------QRDANRQISDLKFKLAKSEQEITALEQN 323
L L+N + ++D+ QR+ ++ +++ K K +S+ E+ + ++
Sbjct: 1416 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKE 1475
Query: 324 VIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKM 383
L +++ + K+A E + + + K E + LQ E+ D TE+L G V LEK+
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS---DLTEQLG-EGGKNVHELEKV 1531
Query: 384 K 384
+
Sbjct: 1532 R 1532
Score = 60.1 bits (144), Expect = 3e-09
Identities = 63/272 (23%), Positives = 124/272 (45%), Gaps = 32/272 (11%)
Query: 117 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 176
K ++ +A+ + E + +K+ L + E + R++ EEK +EK+ LQ
Sbjct: 839 KPLLKSAETEKEMATMKEEFGRIKETLEKSEAR----RKELEEKMVSLLQEKND---LQL 891
Query: 177 QFAEVKEALKQREE---MLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK 233
Q ++ L EE L K+ I L +++ E + +EE+NA
Sbjct: 892 QVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED-------------EEEMNAEL 938
Query: 234 STGDGTLD---IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDM 290
+ L+ LKK +D+ E L +++K K E + K + + D+++ T
Sbjct: 939 TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK-NLTEEMAGLDEIIAKLTK- 996
Query: 291 HVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
LQ + + DL+ + E ++ +L ++ ++LE QV + + E +K+ +L+
Sbjct: 997 EKKALQEAHQQALDDLQVE----EDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLER 1052
Query: 351 EKRKLQRELRSALDKTEELEVSNGHLVKRLEK 382
KRKL+ +L+ + +LE L ++L+K
Sbjct: 1053 AKRKLEGDLKLTQESIMDLENDKLQLEEKLKK 1084
Score = 60.1 bits (144), Expect = 3e-09
Identities = 84/338 (24%), Positives = 149/338 (44%), Gaps = 61/338 (18%)
Query: 94 SIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDN-------EKTNFMYQVDTLKDMLLEL 146
S +TE + +K+ ++E +K+ +L+ EK + QV +D L +
Sbjct: 844 SAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDA 903
Query: 147 EE---QLAESRRQYEEKNKEF------EREKHAHSI-----LQFQFAEVKEALKQREEML 192
EE QL +++ Q E K KE E E +A L+ + +E+K+ + E L
Sbjct: 904 EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTL 963
Query: 193 EKHGIILNSEIATNGETSDTLNNVGYQGP--TKMTKEELNALKSTGDGTLD--------- 241
K + + AT + + + K+TKE+ AL+ LD
Sbjct: 964 AK---VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK-KALQEAHQQALDDLQVEEDKV 1019
Query: 242 -------IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMD 294
++L++ VD+ E LEQ KK++ LE ++ + E D+ T +MD
Sbjct: 1020 NSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKR-------KLEGDL--KLTQESIMD 1070
Query: 295 LQRDANRQISDLKFKLAKSEQEITALE-QNVIRLESQVSRYKSAAENAEKIEDELKAEK- 352
L+ D + LK K Q+ + +E + V+ L+ Q + K E++E+EL+AE+
Sbjct: 1071 LENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQ-KKLKENQARIEELEEELEAERT 1129
Query: 353 -----RKLQRELRSALDK-TEELEVSNGHLVKRLEKMK 384
KL+ +L L++ +E LE + G ++E K
Sbjct: 1130 ARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167
Score = 52.0 bits (123), Expect = 9e-07
Identities = 64/292 (21%), Positives = 125/292 (42%), Gaps = 40/292 (13%)
Query: 90 DTSISIDTEASIRE-IKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 148
DT I +D + +K+++A VE + N L E V+ + E+
Sbjct: 1654 DTQIQLDDAVRANDDLKENIAIVERR-------NNLLQAELEELRAVVEQTERSRKLAEQ 1706
Query: 149 QLAESRRQ----YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK------HGII 198
+L E+ + + + ++K S L +EV+EA+++ EK +
Sbjct: 1707 ELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAM 1766
Query: 199 LNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQI 258
+ E+ +TS L + K ++ + L+ D I LK + + L ++
Sbjct: 1767 MAEELKKEQDTSAHLERM-----KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARV 1821
Query: 259 KKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEIT 318
++L+G+LE QK N + M R + R+I +L ++ + ++ +
Sbjct: 1822 RELEGELEAEQK--------------RNAESVKGM---RKSERRIKELTYQTEEDKKNLL 1864
Query: 319 ALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELE 370
L+ V +L+ +V YK AE AE+ + ++ RK+Q EL A ++ + E
Sbjct: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAE 1916
Score = 47.0 bits (110), Expect = 3e-05
Identities = 74/314 (23%), Positives = 127/314 (40%), Gaps = 55/314 (17%)
Query: 103 EIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNK 162
EI+D + +VE A A LD ++ NF ++ LAE +++YEE
Sbjct: 1426 EIEDLMVDVERSNAAA----AALDKKQRNF--------------DKILAEWKQKYEESQS 1467
Query: 163 EFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPT 222
E E + L + ++K A EE LE E SD +G G
Sbjct: 1468 ELESSQKEARSLSTELFKLKNAY---EESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524
Query: 223 KMTKEELNALKSTGDGTLDIRLKKLVDERECLL--EQIKKLKGQLEERQKIGKLD-NLRS 279
E++ + L+ ++E E L E+ K L+ QLE Q +++ L
Sbjct: 1525 VHELEKVRKQLEVE----KLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1580
Query: 280 EDDVLENGTDMHVMDLQRDANRQISDLKFKL---AKSEQEI----TALEQNVIRLESQVS 332
+D+ +E +R+ R + L+ L +S E+ +E ++ +E Q+S
Sbjct: 1581 KDEEMEQA--------KRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLS 1632
Query: 333 RYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEEL-------EVSNGHLVKRLEKMKA 385
A A+K L++ + Q +L A+ ++L E N L LE+++A
Sbjct: 1633 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1692
Query: 386 -----NRSALLSQQ 394
RS L++Q
Sbjct: 1693 VVEQTERSRKLAEQ 1706
Score = 35.8 bits (81), Expect = 0.069
Identities = 53/229 (23%), Positives = 103/229 (44%), Gaps = 45/229 (19%)
Query: 160 KNKEFEREKHAHSILQFQFAEVKEALKQ----REEMLEKHGIILNSEIATNGETSDTLNN 215
K+ E E+E + ++ +F +KE L++ R+E+ EK +L + N+
Sbjct: 843 KSAETEKEM---ATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEK-----------ND 888
Query: 216 VGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLD 275
+ Q + ++ LN + R +L+ + L ++K++ +LE+ +++
Sbjct: 889 LQLQ--VQAEQDNLNDAEE--------RCDQLIKNKIQLEAKVKEMNERLEDEEEMNA-- 936
Query: 276 NLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYK 335
L ++ LE+ +L++D I DL+ LAK E+E A E V L +++
Sbjct: 937 ELTAKKRKLED----ECSELKKD----IDDLELTLAKVEKEKHATENKVKNLTEEMA--- 985
Query: 336 SAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMK 384
++I +L EK+ LQ + ALD + E L K K++
Sbjct: 986 ----GLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLE 1030
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 62.0 bits (149), Expect = 9e-10
Identities = 97/436 (22%), Positives = 177/436 (40%), Gaps = 83/436 (19%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
E + + A+L K A E R++ E+Q++E+E+ K E S ++ A A
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRK--LEGDSTDLSDQIAELQA 1069
Query: 78 SLGGTSSRRGSGDTSIS-----IDTEAS--------IREIKDSLAEVEEKYKKAMVSNAQ 124
+ + + + ++ EA+ IRE++ ++E++E + S +
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
Query: 125 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 184
+ +K + +++ LK ELE+ L + Q E ++K RE+ + + + E K
Sbjct: 1130 AEKQKRDLGEELEALKT---ELEDTLDSTAAQQELRSK---REQEVNILKKTLEEEAKTH 1183
Query: 185 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGD---GTLD 241
Q +EM +KH + E ++ L TK K L K T + G L
Sbjct: 1184 EAQIQEMRQKHSQAVE-------ELAEQLEQ------TKRVKANLEKAKQTLENERGELA 1230
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEERQ-KIGKLDNLRSE--DDV------LENGTDM-- 290
+K L+ + + KK++ QL+E Q K + + +R+E D V L+N T +
Sbjct: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS 1290
Query: 291 ---------------------HVMDLQRDANRQISDLKFKLAKSEQEITA---------- 319
+L ++ NRQ L KL + E E +
Sbjct: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
Query: 320 ----LEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGH 375
LE+ + L +QV+ K E++ + + KRKLQ++L + EE +
Sbjct: 1351 AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDK 1410
Query: 376 LVKRLEKMKANRSALL 391
L K +++ LL
Sbjct: 1411 LEKTKTRLQQELDDLL 1426
Score = 58.5 bits (140), Expect = 1e-08
Identities = 79/381 (20%), Positives = 167/381 (43%), Gaps = 43/381 (11%)
Query: 39 EIRMKELERQQKEVE------ERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 92
E + K++E Q +E++ ER + +K ++ L T G S+ S +
Sbjct: 1244 EHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT-----GLLSQSDSKSSK 1298
Query: 93 ISIDTEASIREIKDSLAEVEEKYKKAMVSNA---QLDNEKTNFMYQVDTLKDMLLELEEQ 149
++ D A +++D+ ++E+ ++ + + Q+++EK +F Q++ ++ LE+Q
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Query: 150 LAESRRQYEEKNKEFERE----KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIAT 205
+A Q + K+ E + A + + +++ ++ EE + + + ++
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
Query: 206 NGETSDTLNNVGYQGPTKMTKEE--------LNALKSTGDGTLDIRLKKLVDEREC---- 253
E D L ++ +Q + E+ L K+ + R + + RE
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
Query: 254 -----LLEQIKKLKGQLEERQKIGKL---DNLRSEDDVLENGTDMHVMDLQRDA-NRQIS 304
LE+ + K +LE K + D + S+DDV G +H ++ + A +Q+
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDV---GKSVHELEKSKRALEQQVE 1535
Query: 305 DLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRK-LQRELRSAL 363
++K +L + E E+ A E +RLE + K+ E + DE EK+K L R++R
Sbjct: 1536 EMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME 1595
Query: 364 DKTEELEVSNGHLVKRLEKMK 384
+ E+ V +K++
Sbjct: 1596 AELEDERKQRSMAVAARKKLE 1616
Score = 58.2 bits (139), Expect = 1e-08
Identities = 74/370 (20%), Positives = 161/370 (43%), Gaps = 44/370 (11%)
Query: 41 RMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 100
++K++E ++ E+ E++ E+ N+ A A + ++ D+ ++T
Sbjct: 1330 KLKQVEDEKNSFREQLEEE--EEAKHNLEKQIATLHAQVA--DMKKKMEDSVGCLETAEE 1385
Query: 101 I-REIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEE 159
+ R+++ L + +++++ + + +L+ KT ++D D+L++L+ Q +S E+
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD---DLLVDLDHQ-RQSACNLEK 1441
Query: 160 KNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ 219
K K+F++ + ++AE ++ + E + L + E L + Q
Sbjct: 1442 KQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQ 1501
Query: 220 GPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRS 279
T+M E+L + K + + +L + L +Q++++K QLEE + D L++
Sbjct: 1502 FRTEM--EDLMSSKDD----VGKSVHELEKSKRALEQQVEEMKTQLEELE-----DELQA 1550
Query: 280 EDDV---LENGTDMHVMDLQRDA---NRQISDLKFKLAKSEQEITA-------------- 319
+D LE +RD + Q + K +L + +E+ A
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVA 1610
Query: 320 ----LEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGH 375
LE ++ LE+ + + A K +L+A+ + REL EE+
Sbjct: 1611 ARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
Query: 376 LVKRLEKMKA 385
K+L+ M+A
Sbjct: 1671 NEKKLKSMEA 1680
Score = 52.0 bits (123), Expect = 9e-07
Identities = 70/293 (23%), Positives = 131/293 (44%), Gaps = 22/293 (7%)
Query: 102 REIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKN 161
R+ ++ +A+ EE K V QL E N + +++TL+ L+ + QL E + E
Sbjct: 842 RQEEEMMAKEEELVK---VREKQLAAE--NRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
Query: 162 KEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGP 221
E E + + + + E+ L+ R E E+ L +E + L +
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 222 TKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKL---KGQLEERQKIGKLD-NL 277
+ K +L + T + +LKKL +E+ L +Q KL K LE+R I + NL
Sbjct: 957 SARQKLQLEKV------TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDR--IAEFTTNL 1008
Query: 278 RSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSA 337
E++ ++ + L+ I+DL+ +L + E++ LE+ +LE +
Sbjct: 1009 TEEEEKSKS-----LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQ 1063
Query: 338 AENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSAL 390
+ ELK + K + EL++AL + EE +K++ ++++ S L
Sbjct: 1064 IAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISEL 1116
Score = 50.8 bits (120), Expect = 2e-06
Identities = 81/392 (20%), Positives = 158/392 (40%), Gaps = 48/392 (12%)
Query: 18 EAQKLAEARLAAKRA-------ARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPG 70
+A+ E L A +A R E E + K+L RQ +E+E E E+ R+M
Sbjct: 1553 DAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED---ERKQRSMAV 1609
Query: 71 LSAATL--------ASLGGTSSRRGSGDTSI---SIDTEASIREIKDSLAEVEEKYKKAM 119
+ L A + + R + + +RE+ D+ A EE +A
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 120 VSNAQLDNEKTNFMYQVDTLKDMLLELEEQLA---ESRRQYEEKNKEFEREKHAHSILQF 176
+NEK ++ +++ +++L+E+LA ++RQ +++ E E S
Sbjct: 1670 ------ENEK-----KLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
Query: 177 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTG 236
E K L+ R LE+ L E +D L Q +LN +S
Sbjct: 1719 LALEEKRRLEARIAQLEEE---LEEEQGNTELINDRLKKANLQ--IDQINTDLNLERSHA 1773
Query: 237 DGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQ 296
+ R ++L + + L ++++++G ++ + K + L ++ LE D + Q
Sbjct: 1774 QKNENAR-QQLERQNKELKVKLQEMEGTVKSKYK-ASITALEAKIAQLEEQLDNETKERQ 1831
Query: 297 ------RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKA 350
R +++ D+ ++ + + + +++ + K E AE+ A
Sbjct: 1832 AACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA 1891
Query: 351 EKRKLQRELRSALDKTEELEVSNGHLVKRLEK 382
+RKLQREL A + + + L +L +
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
Score = 47.8 bits (112), Expect = 2e-05
Identities = 73/406 (17%), Positives = 174/406 (42%), Gaps = 36/406 (8%)
Query: 8 QSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEER--PEKDFTEKGS 65
Q E+ E K+ E +LAA+ R E +L ++ +++E+ E + +
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAEN--RLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE 900
Query: 66 RNMPGLSAAT--LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNA 123
L+A L + R + +A ++++ ++ E+EE+ ++ +
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 124 QLDNEKTNFMYQVDTLKDMLLELEEQ---LAESRRQYEEKNKEF-----EREKHAHSILQ 175
+L EK ++ L++ + LE+Q LA+ ++ E++ EF E E+ + S+ +
Sbjct: 961 KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK 1020
Query: 176 FQ------FAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVG-YQGPTKMTKEE 228
+ +++E L++ E+ ++ + + G+++D + + Q K +
Sbjct: 1021 LKNKHEAMITDLEERLRREEKQRQE---LEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 229 LNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGT 288
L + L R+++ ++ L++I++L+ Q+ E Q ED E +
Sbjct: 1078 LAKKEEELQAAL-ARVEEEAAQKNMALKKIRELESQISELQ----------EDLESERAS 1126
Query: 289 DMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKI-EDE 347
+RD ++ LK +L + A ++ + E +V+ K E K E +
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186
Query: 348 LKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
++ ++K + + ++ E+ + +L K + ++ R L ++
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Score = 46.6 bits (109), Expect = 4e-05
Identities = 83/396 (20%), Positives = 171/396 (43%), Gaps = 52/396 (13%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLA 77
E K EA++ R ++A E ++LE Q K V+ EK ++ N G A +
Sbjct: 1178 EEAKTHEAQIQEMRQKHSQAVEELAEQLE-QTKRVKANLEK--AKQTLENERGELANEVK 1234
Query: 78 SLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD 137
L +G GD+ E ++++ L E++ K+ + +L ++ T ++D
Sbjct: 1235 VL-----LQGKGDS------EHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD 1283
Query: 138 TLKDMLLE--------------LEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKE 183
+ +L + LE QL +++ +E+N R+K + S Q + K
Sbjct: 1284 NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN----RQKLSLSTKLKQVEDEKN 1339
Query: 184 ALKQREEMLEKHGIILNSEIAT-NGETSDTLNNVGYQGPTKMTKEELNA-LKSTGDGTLD 241
+ +++ E E+ L +IAT + + +D + T EE+ L+ +G
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEG--- 1396
Query: 242 IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANR 301
L + +E+ ++++K K +L++ +LD+L + D + + ++ Q+ ++
Sbjct: 1397 --LSQRHEEKVAAYDKLEKTKTRLQQ-----ELDDLLVDLDH-QRQSACNLEKKQKKFDQ 1448
Query: 302 QISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRS 361
+++ K AK +E E E++ A E A + + EL+ ++ + E+
Sbjct: 1449 LLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Query: 362 ALDKTE-------ELEVSNGHLVKRLEKMKANRSAL 390
+ + ELE S L +++E+MK L
Sbjct: 1509 LMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/273 (19%), Positives = 115/273 (42%), Gaps = 28/273 (10%)
Query: 135 QVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK 194
+V L + + EE +A+ + + K+ E + Q + E L+ +E++ +
Sbjct: 833 KVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE 892
Query: 195 HGIILNSEIATNGETS--DTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERE 252
+ +E T+ L + + ++ +EE R + L E++
Sbjct: 893 TELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE-------------RCQHLQAEKK 939
Query: 253 CLLEQIKKLKGQLEE----RQKI--------GKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
+ + I++L+ QLEE RQK+ KL L E +LE+ + + ++
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILED-QNCKLAKEKKLLE 998
Query: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELR 360
+I++ L + E++ +L + + E+ ++ + EK EL+ +RKL+ +
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 361 SALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
D+ EL+ L +L K + A L++
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 62.0 bits (149), Expect = 9e-10
Identities = 65/280 (23%), Positives = 125/280 (44%), Gaps = 26/280 (9%)
Query: 117 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 176
K ++ +A+ + E + +KD L + E + R++ EEK +EK+ LQ
Sbjct: 843 KPLLKSAETEKEMATMKEEFQKIKDELAKSEAK----RKELEEKMVTLLKEKND---LQL 895
Query: 177 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTG 236
Q E L EE ++ ++ ++I + + +EE+NA +
Sbjct: 896 QVQAEAEGLADAEERCDQ---LIKTKIQLEAKIKEVTERAE-------DEEEINAELTAK 945
Query: 237 DGTLD---IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVM 293
L+ LKK +D+ E L +++K K E + K + + D+ + T
Sbjct: 946 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK-NLTEEMAGLDETIAKLTK-EKK 1003
Query: 294 DLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKR 353
LQ + + DL+ + E ++ L + I+LE QV + + E +K+ +L+ KR
Sbjct: 1004 ALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KL+ +L+ A + ++E L ++L+K + S L S+
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Score = 60.1 bits (144), Expect = 3e-09
Identities = 82/430 (19%), Positives = 194/430 (45%), Gaps = 73/430 (16%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKE-----LERQQKEVEER 55
+T +++D L ++ + R+ +RA R ++++ + +E ++++++E+
Sbjct: 1026 LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK 1085
Query: 56 PEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKY 115
+K E +++L + + ++ I + I+E++ + E+EE+
Sbjct: 1086 LKKKEFE-------------ISNL----QSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 116 KKAMVSNAQLDNEKTNFMYQVDTLKDMLLEL--------------EEQLAESRRQYEEKN 161
+ S A+ + ++++ +++ + + L E E + + RR EE
Sbjct: 1129 EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT 1188
Query: 162 KEFE------REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEI---ATNGETSDT 212
+ E R+KHA S+ + E + L++ ++ LEK + EI A+N ET
Sbjct: 1189 LQHEATAATLRKKHADSVA--ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSK 1246
Query: 213 LNNVGYQGPTKMTKEELNALKSTGD-------------GTLDI---RLKKLVDERECLLE 256
+ + +++L+ LKS + G L + +DE+E L+
Sbjct: 1247 AKG-NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVS 1305
Query: 257 QIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQE 316
Q+ +G+ Q+I +L + E+++ H + ++R DL + + EQE
Sbjct: 1306 QLS--RGKQAFTQQIEELKR-QLEEEIKAKNALAHAL----QSSRHDCDLLREQYEEEQE 1358
Query: 317 ITA-LEQNVIRLESQVSRYKSAAE-NAEKIEDELKAEKRKLQRELRSALDKTEELEVSNG 374
A L++ + + ++V+++++ E +A + +EL+ K+KL + L++A + E +
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418
Query: 375 HLVKRLEKMK 384
L K ++++
Sbjct: 1419 SLEKTKQRLQ 1428
Score = 57.8 bits (138), Expect = 2e-08
Identities = 78/397 (19%), Positives = 174/397 (43%), Gaps = 30/397 (7%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEVEERPE-KDFTEK 63
A ++ L+ E L E A+L ++ A EA + + +L+ ++ +V + K E+
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQ 1035
Query: 64 GSRNMPGL--SAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS 121
++ G L + R+ GD ++ + SI +I++ +++EK KK
Sbjct: 1036 QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA---QESIMDIENEKQQLDEKLKKK--- 1089
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 181
+ E +N +++ + + ++L++++ E + + EE +E E E+ + + + Q +++
Sbjct: 1090 ----EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLD 241
L++ E LE+ G +++I N + + + +L + T
Sbjct: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKM---------RRDLEEATLQHEATAA 1196
Query: 242 IRLKKLVDERECLLEQI---KKLKGQLEERQKIGKL--DNLRSEDDVLENGTDMHVMDLQ 296
KK D L EQI +++K +LE+ + K+ D+L S + + ++ +
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG-NLEKMC 1255
Query: 297 RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQ 356
R Q+S+LK K + ++ I L RL+++ + + E + +L K+
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315
Query: 357 RELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+++ + EE + L L+ + + L Q
Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352
Score = 53.9 bits (128), Expect = 2e-07
Identities = 82/353 (23%), Positives = 145/353 (41%), Gaps = 69/353 (19%)
Query: 46 ERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS--IDTEASIRE 103
E ++KE+EE+ EK L A G + D I I EA I+E
Sbjct: 873 EAKRKELEEKMVTLLKEKND-----LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKE 927
Query: 104 IKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKE 163
+ + + EE NA+L +K + LK + +LE LA +
Sbjct: 928 VTERAEDEEE-------INAELTAKKRKLEDECSELKKDIDDLELTLA-----------K 969
Query: 164 FEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTK 223
E+EKHA +VK ++ + E + + A TL+++ +
Sbjct: 970 VEKEKHATE------NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL------Q 1017
Query: 224 MTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDV 283
++++N L I+L++ VD+ E LEQ KKL+ LE ++ + D +++ +
Sbjct: 1018 AEEDKVNTLTKA-----KIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESI 1072
Query: 284 LENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNV-------IRLESQVSRYKS 336
+ D + L KL K E EI+ L+ + I+L+ ++ K
Sbjct: 1073 M-------------DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKI---KE 1116
Query: 337 AAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
E++E+E++AE+ + + D + ELE + +RLE+ SA
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELE----EISERLEEAGGATSA 1165
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/311 (21%), Positives = 137/311 (44%), Gaps = 33/311 (10%)
Query: 90 DTSISIDTEASIRE-IKDSLAEVEEKYK--KAMVSNAQLDNEKTNFMYQVDTLKDMLLEL 146
DT I +D +E +K+ LA VE + +A + + E+T ++ + LL+
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKI--AEQELLDA 1715
Query: 147 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK---HGIILNSEI 203
E++ Q ++ + S +Q + ++ + + EE +K ++ E+
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL 1775
Query: 204 ATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKG 263
+TS L + K ++ + L+ D + LK + + L ++++L+G
Sbjct: 1776 KKEQDTSAHLERM-----KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 1830
Query: 264 QLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQN 323
++E QK R+ + V G H R++ +L ++ + + I L+
Sbjct: 1831 EVESEQK-------RNAEAV--KGLRKH--------ERRVKELTYQTEEDRKNILRLQDL 1873
Query: 324 VIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKM 383
V +L+++V YK AE AE+ + A+ RKLQ EL A E +++ + K K
Sbjct: 1874 VDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEA---EERADIAESQVNKLRVKS 1930
Query: 384 KANRSALLSQQ 394
+ + ++S++
Sbjct: 1931 REVHTKVISEE 1941
Score = 50.4 bits (119), Expect = 3e-06
Identities = 89/444 (20%), Positives = 169/444 (38%), Gaps = 104/444 (23%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTS 83
E + A+RA+RA+A + R +L R+ +E+ ER E E G +
Sbjct: 1125 EEEIEAERASRAKAEKQR-SDLSRELEEISERLE----EAGGATSAQIEMNKKREAEFQK 1179
Query: 84 SRRGSGDTSISIDTEASIREIK--DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD---- 137
RR + ++ + A+ K DS+AE+ E+ +L+ EK+ ++D
Sbjct: 1180 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 138 ----------TLKDMLLELEEQLAESRRQYEEKNK-----------------EFEREKHA 170
L+ M LE+QL+E + + EE+ + EF R+
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE 1299
Query: 171 HSILQFQFAEVKEALKQREEMLEK-------------HGI--------ILNSEIATNGET 209
L Q + K+A Q+ E L++ H + +L + E+
Sbjct: 1300 KEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQES 1359
Query: 210 SDTLNNVGYQGPTKM----TKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL 265
L + T++ TK E +A++ T + L+ KKL + E ++ + +
Sbjct: 1360 KAELQRALSKANTEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQAAEEHVEAVNAKC 1417
Query: 266 EERQKIGKLDNLRSEDDVLE----NGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALE 321
+K + ED +L+ N + QR+ ++ +++ K K ++ E+ A +
Sbjct: 1418 ASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1477
Query: 322 QNVIRLESQVSRYKSAAENA-----------------------------------EKIED 346
+ L +++ + K+A E + EKI+
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537
Query: 347 ELKAEKRKLQRELRSALDKTEELE 370
+++ EK +LQ L A E E
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEE 1561
Score = 47.8 bits (112), Expect = 2e-05
Identities = 85/437 (19%), Positives = 178/437 (40%), Gaps = 84/437 (19%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPG 70
EID L+ + +++A+ ++ R E ++ EL+ +++E ++R D T + R
Sbjct: 1233 EIDDLASNVETVSKAKGNLEKMCRT--LEDQLSELKSKEEE-QQRLINDLTAQRGR---- 1285
Query: 71 LSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKT 130
L + G SR+ ++ + + E++ + ++ + + L +
Sbjct: 1286 -----LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 131 NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE--REKHAHSILQF--QFAEVKEALK 186
+ + D L++ E +E AE +R + N E R K+ +Q + E K+ L
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 187 QREEMLEKHGIILNSEIATNGETSDTLNN------------------------------V 216
QR + E+H +N++ A+ +T L N
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 217 GYQGPTKMTKEELNA--------------LKSTGDGTLDIRLKKLVDERECLLEQIKKLK 262
++ + T EL A +K+ + +LD +L+ L E + L ++I L
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD-QLETLKRENKNLQQEISDLT 1519
Query: 263 GQLEERQK-IGKLDNLRSEDD--------VLENGT------DMHVMDLQRDANRQISDLK 307
Q+ E K I +L+ ++ + + LE + ++ +Q + N+ S++
Sbjct: 1520 EQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1579
Query: 308 FKLAKSEQEITALEQNVIR--------LESQVSRYKSAAENAEKIEDELKAEKRKLQREL 359
K+A+ ++EI L++N IR L++++ A +K+E +L + +L
Sbjct: 1580 RKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHAN 1639
Query: 360 RSALDKTEELEVSNGHL 376
R A + + G L
Sbjct: 1640 RMAAEALRNYRNTQGIL 1656
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 62.0 bits (149), Expect = 9e-10
Identities = 65/280 (23%), Positives = 125/280 (44%), Gaps = 26/280 (9%)
Query: 117 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 176
K ++ +A+ + E + +KD L + E + R++ EEK +EK+ LQ
Sbjct: 843 KPLLKSAETEKEMATMKEEFQKIKDELAKSEAK----RKELEEKMVTLLKEKND---LQL 895
Query: 177 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTG 236
Q E L EE ++ ++ ++I + + +EE+NA +
Sbjct: 896 QVQAEAEGLADAEERCDQ---LIKTKIQLEAKIKEVTERAE-------DEEEINAELTAK 945
Query: 237 DGTLD---IRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVM 293
L+ LKK +D+ E L +++K K E + K + + D+ + T
Sbjct: 946 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK-NLTEEMAGLDETIAKLTK-EKK 1003
Query: 294 DLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKR 353
LQ + + DL+ + E ++ L + I+LE QV + + E +K+ +L+ KR
Sbjct: 1004 ALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 354 KLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
KL+ +L+ A + ++E L ++L+K + S L S+
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Score = 60.1 bits (144), Expect = 3e-09
Identities = 82/430 (19%), Positives = 194/430 (45%), Gaps = 73/430 (16%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKE-----LERQQKEVEER 55
+T +++D L ++ + R+ +RA R ++++ + +E ++++++E+
Sbjct: 1026 LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK 1085
Query: 56 PEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKY 115
+K E +++L + + ++ I + I+E++ + E+EE+
Sbjct: 1086 LKKKEFE-------------ISNL----QSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 116 KKAMVSNAQLDNEKTNFMYQVDTLKDMLLEL--------------EEQLAESRRQYEEKN 161
+ S A+ + ++++ +++ + + L E E + + RR EE
Sbjct: 1129 EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT 1188
Query: 162 KEFE------REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEI---ATNGETSDT 212
+ E R+KHA S+ + E + L++ ++ LEK + EI A+N ET
Sbjct: 1189 LQHEATAATLRKKHADSVA--ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSK 1246
Query: 213 LNNVGYQGPTKMTKEELNALKSTGD-------------GTLDI---RLKKLVDERECLLE 256
+ + +++L+ LKS + G L + +DE+E L+
Sbjct: 1247 AKG-NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVS 1305
Query: 257 QIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQE 316
Q+ +G+ Q+I +L + E+++ H + ++R DL + + EQE
Sbjct: 1306 QLS--RGKQAFTQQIEELKR-QLEEEIKAKNALAHAL----QSSRHDCDLLREQYEEEQE 1358
Query: 317 ITA-LEQNVIRLESQVSRYKSAAE-NAEKIEDELKAEKRKLQRELRSALDKTEELEVSNG 374
A L++ + + ++V+++++ E +A + +EL+ K+KL + L++A + E +
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418
Query: 375 HLVKRLEKMK 384
L K ++++
Sbjct: 1419 SLEKTKQRLQ 1428
Score = 57.8 bits (138), Expect = 2e-08
Identities = 78/397 (19%), Positives = 174/397 (43%), Gaps = 30/397 (7%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEVEERPE-KDFTEK 63
A ++ L+ E L E A+L ++ A EA + + +L+ ++ +V + K E+
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQ 1035
Query: 64 GSRNMPGL--SAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS 121
++ G L + R+ GD ++ + SI +I++ +++EK KK
Sbjct: 1036 QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA---QESIMDIENEKQQLDEKLKKK--- 1089
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 181
+ E +N +++ + + ++L++++ E + + EE +E E E+ + + + Q +++
Sbjct: 1090 ----EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLD 241
L++ E LE+ G +++I N + + + +L + T
Sbjct: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKM---------RRDLEEATLQHEATAA 1196
Query: 242 IRLKKLVDERECLLEQI---KKLKGQLEERQKIGKL--DNLRSEDDVLENGTDMHVMDLQ 296
KK D L EQI +++K +LE+ + K+ D+L S + + ++ +
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG-NLEKMC 1255
Query: 297 RDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQ 356
R Q+S+LK K + ++ I L RL+++ + + E + +L K+
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315
Query: 357 RELRSALDKTEELEVSNGHLVKRLEKMKANRSALLSQ 393
+++ + EE + L L+ + + L Q
Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352
Score = 53.9 bits (128), Expect = 2e-07
Identities = 82/353 (23%), Positives = 145/353 (41%), Gaps = 69/353 (19%)
Query: 46 ERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS--IDTEASIRE 103
E ++KE+EE+ EK L A G + D I I EA I+E
Sbjct: 873 EAKRKELEEKMVTLLKEKND-----LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKE 927
Query: 104 IKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKE 163
+ + + EE NA+L +K + LK + +LE LA +
Sbjct: 928 VTERAEDEEE-------INAELTAKKRKLEDECSELKKDIDDLELTLA-----------K 969
Query: 164 FEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTK 223
E+EKHA +VK ++ + E + + A TL+++ +
Sbjct: 970 VEKEKHATE------NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL------Q 1017
Query: 224 MTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDV 283
++++N L I+L++ VD+ E LEQ KKL+ LE ++ + D +++ +
Sbjct: 1018 AEEDKVNTLTKA-----KIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESI 1072
Query: 284 LENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNV-------IRLESQVSRYKS 336
+ D + L KL K E EI+ L+ + I+L+ ++ K
Sbjct: 1073 M-------------DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKI---KE 1116
Query: 337 AAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSA 389
E++E+E++AE+ + + D + ELE + +RLE+ SA
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELE----EISERLEEAGGATSA 1165
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/311 (21%), Positives = 137/311 (44%), Gaps = 33/311 (10%)
Query: 90 DTSISIDTEASIRE-IKDSLAEVEEKYK--KAMVSNAQLDNEKTNFMYQVDTLKDMLLEL 146
DT I +D +E +K+ LA VE + +A + + E+T ++ + LL+
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKI--AEQELLDA 1715
Query: 147 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK---HGIILNSEI 203
E++ Q ++ + S +Q + ++ + + EE +K ++ E+
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL 1775
Query: 204 ATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKG 263
+TS L + K ++ + L+ D + LK + + L ++++L+G
Sbjct: 1776 KKEQDTSAHLERM-----KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 1830
Query: 264 QLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQN 323
++E QK R+ + V G H R++ +L ++ + + I L+
Sbjct: 1831 EVESEQK-------RNAEAV--KGLRKH--------ERRVKELTYQTEEDRKNILRLQDL 1873
Query: 324 VIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKM 383
V +L+++V YK AE AE+ + A+ RKLQ EL A E +++ + K K
Sbjct: 1874 VDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEA---EERADIAESQVNKLRVKS 1930
Query: 384 KANRSALLSQQ 394
+ + ++S++
Sbjct: 1931 REVHTKVISEE 1941
Score = 50.4 bits (119), Expect = 3e-06
Identities = 89/444 (20%), Positives = 169/444 (38%), Gaps = 104/444 (23%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTS 83
E + A+RA+RA+A + R +L R+ +E+ ER E E G +
Sbjct: 1125 EEEIEAERASRAKAEKQR-SDLSRELEEISERLE----EAGGATSAQIEMNKKREAEFQK 1179
Query: 84 SRRGSGDTSISIDTEASIREIK--DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD---- 137
RR + ++ + A+ K DS+AE+ E+ +L+ EK+ ++D
Sbjct: 1180 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 138 ----------TLKDMLLELEEQLAESRRQYEEKNK-----------------EFEREKHA 170
L+ M LE+QL+E + + EE+ + EF R+
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE 1299
Query: 171 HSILQFQFAEVKEALKQREEMLEK-------------HGI--------ILNSEIATNGET 209
L Q + K+A Q+ E L++ H + +L + E+
Sbjct: 1300 KEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQES 1359
Query: 210 SDTLNNVGYQGPTKM----TKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQL 265
L + T++ TK E +A++ T + L+ KKL + E ++ + +
Sbjct: 1360 KAELQRALSKANTEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQAAEEHVEAVNAKC 1417
Query: 266 EERQKIGKLDNLRSEDDVLE----NGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALE 321
+K + ED +L+ N + QR+ ++ +++ K K ++ E+ A +
Sbjct: 1418 ASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1477
Query: 322 QNVIRLESQVSRYKSAAENA-----------------------------------EKIED 346
+ L +++ + K+A E + EKI+
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537
Query: 347 ELKAEKRKLQRELRSALDKTEELE 370
+++ EK +LQ L A E E
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEE 1561
Score = 47.8 bits (112), Expect = 2e-05
Identities = 85/437 (19%), Positives = 178/437 (40%), Gaps = 84/437 (19%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPG 70
EID L+ + +++A+ ++ R E ++ EL+ +++E ++R D T + R
Sbjct: 1233 EIDDLASNVETVSKAKGNLEKMCRT--LEDQLSELKSKEEE-QQRLINDLTAQRGR---- 1285
Query: 71 LSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKT 130
L + G SR+ ++ + + E++ + ++ + + L +
Sbjct: 1286 -----LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 131 NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE--REKHAHSILQF--QFAEVKEALK 186
+ + D L++ E +E AE +R + N E R K+ +Q + E K+ L
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 187 QREEMLEKHGIILNSEIATNGETSDTLNN------------------------------V 216
QR + E+H +N++ A+ +T L N
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 217 GYQGPTKMTKEELNA--------------LKSTGDGTLDIRLKKLVDERECLLEQIKKLK 262
++ + T EL A +K+ + +LD +L+ L E + L ++I L
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD-QLETLKRENKNLQQEISDLT 1519
Query: 263 GQLEERQK-IGKLDNLRSEDD--------VLENGT------DMHVMDLQRDANRQISDLK 307
Q+ E K I +L+ ++ + + LE + ++ +Q + N+ S++
Sbjct: 1520 EQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1579
Query: 308 FKLAKSEQEITALEQNVIR--------LESQVSRYKSAAENAEKIEDELKAEKRKLQREL 359
K+A+ ++EI L++N IR L++++ A +K+E +L + +L
Sbjct: 1580 RKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHAN 1639
Query: 360 RSALDKTEELEVSNGHL 376
R A + + G L
Sbjct: 1640 RMAAEALRNYRNTQGIL 1656
>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 61.6 bits (148), Expect = 1e-09
Identities = 69/362 (19%), Positives = 150/362 (41%), Gaps = 37/362 (10%)
Query: 43 KELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASI- 101
+E + + ++ K++ +K S +P + + G + SG D+
Sbjct: 3 EETQHNKLAAAKKKLKEYWQKNSPRVPAGANRNRKTNGSVPEKATSGGCQPPGDSATGFH 62
Query: 102 REIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKN 161
RE S A +++ LD+ ++ LK+ + L++Q + Q EE+
Sbjct: 63 REGPTSSATLKDLESPCQERAVVLDSRSV----EISQLKNTIKSLKQQKKQVEHQLEEEK 118
Query: 162 KEFEREKHAHSILQFQFA--------------EVKEALKQREEMLEKHGIILNSEIATNG 207
K +++ A +L+ Q +K +L+ EE + + L + G
Sbjct: 119 KANNKKQKAKRVLEVQIQTLNIQKGKLNTDLYHMKRSLRYFEEKSKDLAVCLQHSLQRKG 178
Query: 208 ETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEE 267
E L+NV K++ N L S + +L++ + E L Q+ +LK ++
Sbjct: 179 ELESVLSNV-----MATQKKKANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQ 233
Query: 268 RQKIGKLDNLRSEDDVLEN--GTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVI 325
Q D+ E+ G R +++I LK + + + + LE+++
Sbjct: 234 VQ--------LERDECAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLS 285
Query: 326 RLESQVSRYKSAAENAEKIEDELKAEKRKLQR---ELRSALDKTEELEVSNGHLVKRLEK 382
+L++Q++ A E EL+ +++L+R EL++ + K + + + N +R+++
Sbjct: 286 KLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQE 345
Query: 383 MK 384
+
Sbjct: 346 QE 347
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 61.6 bits (148), Expect = 1e-09
Identities = 79/377 (20%), Positives = 172/377 (45%), Gaps = 40/377 (10%)
Query: 8 QSREIDC--LSPEAQKLAEA--------RLAAKRAARA-EAREIRMKELERQQKEVE--- 53
+S+E +C L E QKL + RLAA++AA+ E + LE Q++++
Sbjct: 307 KSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGL 366
Query: 54 --ERPEKDFTEKGSRNMPGLSA-ATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAE 110
++ + D ++ R + L +++A TS+R+ + +S++ ++R++++S E
Sbjct: 367 LLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEE--LSLELSEALRKLENSDKE 424
Query: 111 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 170
+ K + ++++ +Q + +LEE L E+ + E+K ++ ++ K
Sbjct: 425 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEH 484
Query: 171 HSILQFQFAEVKEALKQREEMLEKHGIILNSE----------IATNGETSDTLNNVGYQG 220
+++ + +++ K++++ L+++ L E +T E+S N Q
Sbjct: 485 EKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQV 544
Query: 221 PTKMTKEELNALKSTGDGTLDIRL-KKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRS 279
+ KE AL+ +L +L K L E+ L I K R+ D+L
Sbjct: 545 IQDLNKE--IALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQ 602
Query: 280 EDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAE 339
+ L HV + + ++ + K A+ E+EI A E+ + +L +++ + + +
Sbjct: 603 ALEKLN-----HVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQ 657
Query: 340 NAEKIEDELKAEKRKLQ 356
+E E+ A +KL+
Sbjct: 658 ESEL---EVHAFDKKLE 671
Score = 44.3 bits (103), Expect = 2e-04
Identities = 66/322 (20%), Positives = 139/322 (43%), Gaps = 41/322 (12%)
Query: 101 IREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML---LELEEQLAESRRQY 157
++E KDS E+Y+ +V + +++ E + + + +KDM+ L+L E+
Sbjct: 166 LQEQKDSQCLHVEEYQN-LVKDLRVELEAVSEQKR-NIMKDMMKLELDLHGLREETSAHI 223
Query: 158 EEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVG 217
E K+K+ + LQ +F E ++ ++++ L++ +L E L V
Sbjct: 224 ERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQ-------ELEKKLTQV- 275
Query: 218 YQGPTKMTKEELNALKSTGDGT-LDIRLKKLVDER----EC--LLEQIKKLKGQLEERQK 270
+ K+E K T L++ +K+ ++ EC L +++KLK LEE ++
Sbjct: 276 ---QNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQ 332
Query: 271 IGKLD----------------NLRSEDDVLENGT--DMHVMDLQRDANRQISDLKFKLAK 312
+L +L L+ G D D ++ R++ L+ + +
Sbjct: 333 QERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSM 392
Query: 313 SEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVS 372
+E+E T+ + V L ++S EN++K + +L+ + ++ LD+ +
Sbjct: 393 AEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHRE 452
Query: 373 NGHLVKRLEKMKANRSALLSQQ 394
G + +LE+ + LL +
Sbjct: 453 QGSIKCKLEEDLQEATKLLEDK 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.315
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,528,609
Number of Sequences: 37866
Number of extensions: 549537
Number of successful extensions: 8894
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 306
Number of HSP's successfully gapped in prelim test: 768
Number of HSP's that attempted gapping in prelim test: 4429
Number of HSP's gapped (non-prelim): 3478
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.