Search of human proteins with 21040247

Search of human proteins with 21040247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21040247 StAR-related lipid transfer (START) domain
containing 4 [Homo sapiens]
         (205 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21040247 StAR-related lipid transfer (START) domain containin...   432   e-121
gi|32526915 StAR-related lipid transfer protein 5 [Homo sapiens]      132   3e-31
gi|21040261 START domain containing protein 6 [Homo sapiens]          112   3e-25
gi|31543657 StAR-related lipid transfer (START) domain containin...    69   3e-12
gi|56243551 steroidogenic acute regulatory protein isoform 1 [Ho...    52   5e-07
gi|56117848 steroidogenic acute regulatory protein isoform 2 [Ho...    46   3e-05
gi|151301035 START domain containing 7 [Homo sapiens]                  33   0.17 
gi|156151415 phosphatidylcholine transfer protein isoform 1 [Hom...    29   2.4  
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo...    29   3.2  
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]             27   9.3  
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...    27   9.3  
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    27   9.3  
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]                27   9.3  

>gi|21040247 StAR-related lipid transfer (START) domain containing 4
           [Homo sapiens]
          Length = 205

 Score =  432 bits (1111), Expect = e-121
 Identities = 205/205 (100%), Positives = 205/205 (100%)

Query: 1   MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVID 60
           MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVID
Sbjct: 1   MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVID 60

Query: 61  DLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFS 120
           DLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFS
Sbjct: 61  DLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFS 120

Query: 121 YTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGM 180
           YTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGM
Sbjct: 121 YTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGM 180

Query: 181 IPQSAVDTAMASTLTNFYGDLRKAL 205
           IPQSAVDTAMASTLTNFYGDLRKAL
Sbjct: 181 IPQSAVDTAMASTLTNFYGDLRKAL 205


>gi|32526915 StAR-related lipid transfer protein 5 [Homo sapiens]
          Length = 213

 Score =  132 bits (331), Expect = 3e-31
 Identities = 66/203 (32%), Positives = 112/203 (55%), Gaps = 6/203 (2%)

Query: 8   ASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSII 67
           A  +  +   ++QY   +   W++ ++   V+V  +PS EF G LY+ +G++   +  + 
Sbjct: 7   AQMSEAVAEKMLQYRR-DTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGTLEEVW 65

Query: 68  DHIRP--GPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGY 125
           D ++P  G  R+ WD  +T  +I+++  +  CV R +T      +ISPR+FVD      Y
Sbjct: 66  DCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLVLVKRY 125

Query: 126 KEGLLSCG---ISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIP 182
           ++G +S     +       +P FVRG+NHPCG FC PL   P ++ L  +  TDL G +P
Sbjct: 126 EDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDLSGYLP 185

Query: 183 QSAVDTAMASTLTNFYGDLRKAL 205
           Q+ VD+    ++T FY +L+KA+
Sbjct: 186 QNVVDSFFPRSMTRFYANLQKAV 208


>gi|21040261 START domain containing protein 6 [Homo sapiens]
          Length = 220

 Score =  112 bits (279), Expect = 3e-25
 Identities = 58/195 (29%), Positives = 103/195 (52%), Gaps = 4/195 (2%)

Query: 6   DVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYS 65
           D  + A +    ++ Y+  +   W+V K +K +TV  K S +F+G LY+ +G+I +    
Sbjct: 2   DFKAIAQQTAQEVLGYNR-DTSGWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAK 60

Query: 66  IIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGY 125
           + D +     R+ WD  +   +++   + +  +    T       ISPR+F+D  Y   Y
Sbjct: 61  LSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRY 120

Query: 126 KEGL-LSCGISLDWDEKRPE--FVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIP 182
           +  + +    S+D+ E  P   ++RGYNHPCG+ C P+++NP  S L  ++QT++RG + 
Sbjct: 121 EGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLS 180

Query: 183 QSAVDTAMASTLTNF 197
            S ++  M S L NF
Sbjct: 181 PSIIEKTMPSNLVNF 195


>gi|31543657 StAR-related lipid transfer (START) domain containing 3
           [Homo sapiens]
          Length = 445

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 37/129 (28%), Positives = 66/129 (51%), Gaps = 2/129 (1%)

Query: 79  WDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDW 138
           W+  +T+  IL+  E+N  +    +AG    ++SPR+FV+       ++  LS GI+   
Sbjct: 310 WNKTVTACQILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVRRIERRRDRYLSSGIATSH 369

Query: 139 DEKRP--EFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTN 196
             K P  ++VRG N P G+  +    NP        + TDL+G +P+  +  ++A+T+  
Sbjct: 370 SAKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLAATMFE 429

Query: 197 FYGDLRKAL 205
           F   LR+ +
Sbjct: 430 FAFHLRQRI 438


>gi|56243551 steroidogenic acute regulatory protein isoform 1 [Homo
           sapiens]
          Length = 285

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 35/180 (19%), Positives = 80/180 (44%), Gaps = 15/180 (8%)

Query: 41  WRKPSEEFNG------------YLYKAQGVIDDLVYSIIDH-IRPGPCRLDWDSLMTSLD 87
           W+K S++ NG             +++ + V+D  +  + +  +       +W+  +  + 
Sbjct: 96  WKKESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIK 155

Query: 88  ILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDWDE--KRPEF 145
           +L+   ++  +     A    N++ PR+FV            +  G++ D+    ++   
Sbjct: 156 VLQKIGKDTFITHELAAEAAGNLVGPRDFVSVRCAKRRGSTCVLAGMATDFGNMPEQKGV 215

Query: 146 VRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKAL 205
           +R  + P      PL  +P+++ LT  +  DL+G +P+S ++  ++ T  +F   LRK L
Sbjct: 216 IRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKSIINQVLSQTQVDFANHLRKRL 275


>gi|56117848 steroidogenic acute regulatory protein isoform 2 [Homo
           sapiens]
          Length = 267

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 7/167 (4%)

Query: 41  WRKPSEEFNGYLYKAQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMR 100
           W+K S++ NG    ++ V D      ++ +   P    ++ L+  ++ +  +  N   ++
Sbjct: 96  WKKESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIK 155

Query: 101 YTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDWDE--KRPEFVRGYNHPCGWFCV 158
                 L  I  PR+FV            +  G++ D+    ++   +R  + P      
Sbjct: 156 V-----LQKIGGPRDFVSVRCAKRRGSTCVLAGMATDFGNMPEQKGVIRAEHGPTCMVLH 210

Query: 159 PLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKAL 205
           PL  +P+++ LT  +  DL+G +P+S ++  ++ T  +F   LRK L
Sbjct: 211 PLAGSPSKTKLTWLLSIDLKGWLPKSIINQVLSQTQVDFANHLRKRL 257


>gi|151301035 START domain containing 7 [Homo sapiens]
          Length = 370

 Score = 33.1 bits (74), Expect = 0.17
 Identities = 16/67 (23%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 25  EEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSIIDHIR-PGPCRLDWDSLM 83
           +E +W +    K   +WR+P    + Y Y+  G   D+      +++     R  WD+L+
Sbjct: 137 KEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALV 196

Query: 84  TSLDILE 90
             L+++E
Sbjct: 197 IKLEVIE 203


>gi|156151415 phosphatidylcholine transfer protein isoform 1 [Homo
          sapiens]
          Length = 214

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 17/79 (21%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 19 IQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSII-DHIRPGPCRL 77
          +Q  ++    W++  +T  ++++R   ++   Y YK  GV++D   +++ D       R 
Sbjct: 20 LQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRK 79

Query: 78 DWDSLMTSLDILENFEENC 96
           WD  +  L     +E+ C
Sbjct: 80 QWDQYVKEL-----YEQEC 93


>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
           sapiens]
          Length = 776

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 14/65 (21%), Positives = 29/65 (44%)

Query: 14  LKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSIIDHIRPG 73
           +   ++QY + EE + R      +V +    S   +G++Y+ +  I   V + +D I   
Sbjct: 453 MSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGN 512

Query: 74  PCRLD 78
            C  +
Sbjct: 513 DCTFE 517


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score = 27.3 bits (59), Expect = 9.3
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 55  AQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENC 96
           +Q    D  +S  + + PG C+++  SL T   +  NF  NC
Sbjct: 816 SQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNC 857


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
           sapiens]
          Length = 2134

 Score = 27.3 bits (59), Expect = 9.3
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 55  AQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENC 96
           +Q    D  +S  + + PG C+++  SL T   +  NF  NC
Sbjct: 838 SQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNC 879


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
           sapiens]
          Length = 2134

 Score = 27.3 bits (59), Expect = 9.3
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 55  AQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENC 96
           +Q    D  +S  + + PG C+++  SL T   +  NF  NC
Sbjct: 838 SQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNC 879


>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
          Length = 661

 Score = 27.3 bits (59), Expect = 9.3
 Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 5/78 (6%)

Query: 42  RKPSEEFNGYLYKAQGVIDDLVYSIID--HIRPG---PCRLDWDSLMTSLDILENFEENC 96
           ++ +E F+G +   + +  D +    D  HIR        L+   +++  ++ EN ++  
Sbjct: 70  KRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIV 129

Query: 97  CVMRYTTAGQLWNIISPR 114
            +M Y + G+L++ IS R
Sbjct: 130 IIMEYASKGELYDYISER 147


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,945,296
Number of Sequences: 37866
Number of extensions: 341536
Number of successful extensions: 657
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 642
Number of HSP's gapped (non-prelim): 13
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.